James Jaggers, MD
Professor, Surgery-Cardiothoracic

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Medical School:
  • MD, University of Nebraska College of Medicine (1988)
Undergraduate Schools:
  • BS, Chadron State College (NE) (1984)
  • BA, University of Nebraska Medical Center (NE) (1988)
Residency:
  • Oregon Health & Science University, Surgery (1993)
Fellowships:
  • University of Colorado, Thoracic and Cardiac (1996)
  • University of Colorado (Children's Hospital Colorado) Program, Congenital Cardiac Surgery (1996)
Languages: English
Department: Surgery-Cardiothoracic

Professional Titles

  • Professor, Surgery-Cardiothoracic
  • Barton-Elliman Chair in Pediatric Cardiothoracic Surgery
  • Co-Medical Director, The Children’s Hospital of Colorado Heart Institute
  • Section Chief Congenital Heart Surgery UC SOM

Recognition & Awards

  • Top Doctors in Denver, 5280 Magazine (2019)
  • Distinguished Alumnist, Chadron State College (2019)
  • Top Doctors in Denver, 5280 Magazine (2018)
  • Top Doctors in Denver, 5280 Magazine (2017)
  • Top Doctors in Denver, 5280 Magazine (2016)
  • Top Doctors in Denver, 5280 Magazine (2015)
  • Top Doctors in Denver, 5280 Magazine (2014)
  • Top Doctors in Denver, 5280 Magazine (2013)
    Voted a 5280 best doctor by my peers in response to the question, "Which physician would you trust to treat you and your family?"
  • Top Doctors in Denver, 5280 Magazine (2012)
  • Top Doctors in Denver, 5280 Magazine (2011)
    Voted a 5280 best doctor by my peers in response to the question, "Which physician would you trust to treat you and your family?"
  • Meritorious Service Award, AmSECT Pediatric Conference, American Society of Extracorporeal Technology (2006)
  • 1st Place, C Walton Lillehei Resident Forum Session, American Association for Thoracic Surgery (2006)

Teaching

  • Professor (2010)
    School of Medicine, Surgery
  • Program Director for Congenital Cardiac Surgery Residency (2019)
    School of Medicine, Surgery

Publications

  • Schäfer M, Younoszai A, Truong U, Browne LP, Mitchell MB, Jaggers J, Campbell DN, Hunter KS, Ivy DD, Di Maria MV. Influence of aortic stiffness on ventricular function in patients with Fontan circulation. J Thorac Cardiovasc Surg. 2018 Oct 5. [Epub ahead of print] PubMed PMID: 30396734
  • SooHoo MM, Patel SS, Jaggers J, Faubel S, Gist KM. Acute Kidney Injury Defined by Fluid Corrected Creatinine in Neonates After the Norwood Procedure. World J Pediatr Congenit Heart Surg. 2018 Sep;9(5):513-521. PubMed PMID: 30157730
  • Schäfer M, Browne LP, Truong U, Jaggers JJ, Mitchell MB, Malone L, Morgan G, Chatfield K, McLennan D, Turbendian H, Vargas D, Fonseca B, DiMaria M, Shah A, Ivy MP, Barker AJ, Hunter KS, Wilson N, Ivy DD, Campbell DN. Aortic stiffness in adolescent Turner and Marfan syndrome patients. Eur J Cardiothorac Surg. 2018 Apr 19. [Epub ahead of print] PubMed PMID: 29684119
  • Davidson JA, Urban TT, Tong S, Maddux A, Hill G, Frank BS, Watson JD, Jaggers J, Simões EAF, Wischmeyer P. Alkaline Phosphatase Activity and Endotoxemia after Infant Cardiothoracic Surgery. Shock. 2018 Apr 16. [Epub ahead of print] PubMed PMID: 29664834
  • Di Maria MV, Mulvahill M, Jaggers J, Ivy DD, Younoszai AK. Predictive value of presuperior cavopulmonary anastomosis cardiac catheterization at increased altitude. Congenit Heart Dis. 2018 Mar;13(2):311-318. PubMed PMID: 29431283
  • Jaggers J. Primum non nocere when the treatment is worse than the disease. J Thorac Cardiovasc Surg. 2018 Apr;155(4):1769-1770. PubMed PMID: 29397151
  • Sandhu A, Ruckdeschel E, Sauer WH, Collins KK, Kay J, Khanna A, Jaggers J, Campbell D, Mitchell M, Nguyen DT. Perioperative Electrophysiology Study in Tetralogy of Fallot Patients Undergoing Pulmonary Valve Replacement Will Identify Those at High Risk for Subsequent Ventricular Tachycardia. Heart Rhythm. 2018 Jan 9. [Epub ahead of print] PubMed PMID: 29330130
  • Ehrmann DE, Mulvahill M, Harendt S, Church J, Stimmler A, Vichayavilas P, Batz S, Rodgers J, DiMaria M, Jaggers J, Barrett C, Kaufman J. Toward standardization of care: The feeding readiness assessment after congenital cardiac surgery. Congenit Heart Dis. 2017 Nov 17. [Epub ahead of print] PubMed PMID: 29148256
  • Ehrmann DE, Mulvahill M, Harendt S, Church J, Stimmler A, Vichayavilas P, Batz S, Rodgers J, DiMaria M, Jaggers J, Barrett C, Kaufman J. Toward standardization of care: The feeding readiness assessment after congenital cardiac surgery. Congenit Heart Dis. 2017 Nov 17. [Epub ahead of print] PubMed PMID: 29148256
  • Davidson JA, Urban TT, Baird C, Tong S, Woodruff A, Twite M, Jaggers J, Simões EAF, Wischmeyer P. Alkaline Phosphatase in Infant Cardiopulmonary Bypass: Kinetics and Relationship to Organ Injury and Major Cardiovascular Events. J Pediatr. 2017 Nov;190:49-55.e2. PubMed PMID: 29144270
  • Deng XS, Meng X, Venardos N, Song R, Yamanaka K, Fullerton D, Jaggers J. Autophagy negatively regulates pro-osteogenic activity in human aortic valve interstitial cells. J Surg Res. 2017 Oct;218:285-291. PubMed PMID: 28985862
  • Tatman PD, Woulfe KC, Karimpour-Fard A, Jeffrey DA, Jaggers J, Cleveland JC, Nunley K, Taylor MR, Miyamoto SD, Stauffer BL, Sucharov CC. Pediatric dilated cardiomyopathy hearts display a unique gene expression profile. JCI Insight. 2017 Jul 20;2(14). [Epub ahead of print] PubMed PMID: 28724804
  • Jaggers J. New tricks for old dogs. J Thorac Cardiovasc Surg. 2017 May;153(5):1153-1154. PubMed PMID: 28283229
  • Lawson DS, Eilers D, Osorio Lujan S, Bortot M, Jaggers J. Hemolysis generation from a novel, linear positive displacement blood pump for cardiopulmonary bypass on a six kilogram piglet: a preliminary report. Perfusion. 2016 Nov 16. [Epub ahead of print] PubMed PMID: 27856841
  • Clopton RG, Friesen R, Partrick D, Wilson N, Jaggers J, Ivy DD, Schwartz LI, Ing RJ. The Anesthetic Challenges of Lung Biopsy-Associated Intrathoracic Hemorrhage in a Child With Suprasystemic Pulmonary Hypertension. Semin Cardiothorac Vasc Anesth. 2016 Nov 3. [Epub ahead of print] PubMed PMID: 27815350
  • McRobb CM, Ing RJ, Lawson DS, Jaggers J, Twite M. Retrospective analysis of eliminating modified ultrafiltration after pediatric cardiopulmonary bypass. Perfusion. 2016 Oct 5. [Epub ahead of print] PubMed PMID: 27708000
  • Ohye RG, Jaggers JJ, Sade RM. Must Surgeons in Training Programs Allow Residents to Operate on Their Patients to Satisfy Board Requirements?. Ann Thorac Surg. 2016 Jan;101(1):18-23. PubMed PMID: 26694262
  • Lawson DS, Eilers D, Osorio Lujan S, Bortot M, Jaggers J. Hemolysis generation from a novel, linear positive displacement blood pump for cardiopulmonary bypass on a six kilogram piglet: a preliminary report. Perfusion. 2016 Nov 16. [Epub ahead of print] PubMed PMID: 27856841
  • Clopton RG, Friesen R, Partrick D, Wilson N, Jaggers J, Ivy DD, Schwartz LI, Ing RJ. The Anesthetic Challenges of Lung Biopsy-Associated Intrathoracic Hemorrhage in a Child With Suprasystemic Pulmonary Hypertension. Semin Cardiothorac Vasc Anesth. 2016 Nov 3. [Epub ahead of print] PubMed PMID: 27815350
  • McRobb CM, Ing RJ, Lawson DS, Jaggers J, Twite M. Retrospective analysis of eliminating modified ultrafiltration after pediatric cardiopulmonary bypass. Perfusion. 2016 Oct 5. [Epub ahead of print] PubMed PMID: 27708000
  • Deng XS, Meng X, Song R, Fullerton D, Jaggers J. Rapamycin Decreases the Osteogenic Response in Aortic Valve Interstitial Cells Through the Stat3 Pathway. Ann Thorac Surg. 2016 Oct;102(4):1229-38. PubMed PMID: 27209607
  • Zanotti G, Gupta R, Reece TB, Campbell DN, Jaggers J, Babu A. Aortic Valve Sparing Root Replacement With Unroofing and Reconstruction of an Anomalous Right Coronary Artery. Ann Thorac Surg. 2016 May;101(5):1980-2. PubMed PMID: 27106435
  • Ohye RG, Jaggers JJ, Sade RM. Must Surgeons in Training Programs Allow Residents to Operate on Their Patients to Satisfy Board Requirements?. Ann Thorac Surg. 2016 Jan;101(1):18-23. PubMed PMID: 26694262
  • Deng XS, Meng X, Zeng Q, Fullerton D, Mitchell M, Jaggers J. Adult aortic valve interstitial cells have greater responses to toll-like receptor 4 stimulation. Ann Thorac Surg. 2015 Jan;99(1):62-71. PubMed PMID: 25442996
  • Peng E, Campbell DN, Jaggers J, Mitchell MB. Three-Sinus Repair of Elastin Arteriopathy Associated Supravalvar Pulmonary Stenosis With Bilateral Branch Pulmonary Artery Involvement. Ann Thorac Surg. 2015 Aug;100(2):741-3. PubMed PMID: 26234860
  • Peng E, Howley L, Cromblehome TM, Jaggers J. Ex-utero intrapartum treatment as a novel bridging strategy to surgery in hypoplastic left heart syndrome with intact atrial septum-cross-circulation revisited. J Thorac Cardiovasc Surg. 2014 Nov 24. [Epub ahead of print] PubMed PMID: 25595375
  • Jone PN, Bremen C, DiMaria M, Campbell DN, Jaggers J, Younoszai A, Ivy DD. Three-Dimensional Echocardiography Enhances Diagnostic Accuracy of Supramitral Ring. Echocardiography. 2014 Dec 12. [Epub ahead of print] PubMed PMID: 25496227
  • Deng XS, Meng X, Zeng Q, Fullerton D, Mitchell M, Jaggers J. Adult aortic valve interstitial cells have greater responses to toll-like receptor 4 stimulation. Ann Thorac Surg. 2015 Jan;99(1):62-71. PubMed PMID: 25442996
  • Peng E, Howley L, Cromblehome TM, Jaggers J. Ex-utero intrapartum treatment as a novel bridging strategy to surgery in hypoplastic left heart syndrome with intact atrial septum-cross-circulation revisited. J Thorac Cardiovasc Surg. 2014 Nov 24. [Epub ahead of print] PubMed PMID: 25595375
  • Jone PN, Bremen C, DiMaria M, Campbell DN, Jaggers J, Younoszai A, Ivy DD. Three-Dimensional Echocardiography Enhances Diagnostic Accuracy of Supramitral Ring. Echocardiography. 2014 Dec 12. [Epub ahead of print] PubMed PMID: 25496227
  • Goot BH, Jaggers J, Anagnost MR, Collins KK. Multivalvular Replacement and Ventricular Arrhythmias in a Female Child With Congenital Polyvalvular Disease. World J Pediatr Congenit Heart Surg. 2014 Jun 23;5(3):463-466. [Epub ahead of print] PubMed PMID: 24958053
  • Gist KM, Schuchardt EL, Moroze MK, Kaufman J, Cruz Ed, Campbell DN, Mitchell MB, Jaggers J, Collins KK, McCanta AC. Tachyarrhythmia following Norwood operation: a single-center experience. World J Pediatr Congenit Heart Surg. 2014 Apr;5(2):206-10. PubMed PMID: 24668965
  • McFerson MC, McCanta AC, Pan Z, Collins KK, Jaggers J, da Cruz EM, Kaufman J. Tachyarrhythmias After the Norwood Procedure: Relationship and Effect of Vasoactive Agents. Pediatr Cardiol. 2013 Nov 17. [Epub ahead of print] PubMed PMID: 24240783
  • McFerson MC, McCanta AC, Pan Z, Collins KK, Jaggers J, da Cruz EM, Kaufman J. Tachyarrhythmias After the Norwood Procedure: Relationship and Effect of Vasoactive Agents. Pediatr Cardiol. 2013 Nov 17. [Epub ahead of print] PubMed PMID: 24240783
  • Hauck A, da Cruz EM, Jaggers J, Jone PN. Tricuspid Atresia Associated with Truncus Arteriosus versus Aortopulmonary Window: Combining Fetal and Postnatal Echocardiography to Make the Diagnosis. Echocardiography. 2013 Sep 4. [Epub ahead of print] PubMed PMID: 24033694
  • Mejak BL, Ing RJ, McRobb C, Ellis WC, Lawson DS, Twite MD, Jaggers J. Cryoprecipitate and platelet administration during modified ultrafiltration in children less than 10 kg undergoing cardiac surgery. J Extra Corpor Technol. 2013 Jun;45(2):107-11. PubMed PMID: 23930379
  • Kaufmnan J, Twite M, Barrett C, Peyton C, Koehler J, Rannie M, Kahn MG, Schofield S, Ing RJ, Jaggers J, Hyman D, da Cruz EM. A handoff protocol from the cardiovascular operating room to cardiac ICU is associated with improvements in care beyond the immediate postoperative period. Jt Comm J Qual Patient Saf. 2013 Jul;39(7):306-11. PubMed PMID: 23888640
  • Turek JW, Andersen ND, Lawson DS, Bonadonna D, Turley RS, Peters MA, Jaggers J, Lodge AJ. Outcomes before and after implementation of a pediatric rapid-response extracorporeal membrane oxygenation program. Ann Thorac Surg. 2013 Jun;95(6):2140-6; discussion 2146-7. PubMed PMID: 23506632
  • Barrett CS, Jaggers JJ, Cook EF, Graham DA, Yarlagadda VV, Teele SA, Almond CS, Bratton SL, Seeger JD, Dalton HJ, Rycus PT, Laussen PC, Thiagarajan RR. Pediatric ECMO outcomes: comparison of centrifugal versus roller blood pumps using propensity score matching. ASAIO J. 2013 Mar-Apr;59(2):145-51. PubMed PMID: 23438777
  • Gist KM, Barrett CS, Graham DA, Crumback SL, Schuchardt EL, Erickson B, Jaggers J. Pulmonary artery interventions after Norwood procedure: does type or position of shunt predict need for intervention?. J Thorac Cardiovasc Surg. 2013 Jun;145(6):1485-92. PubMed PMID: 23398647
  • Stewart RD, Pasquali SK, Jacobs JP, Benjamin DK, Jaggers J, Cheng J, Mavroudis C, Jacobs ML. Reply: To PMID 22450074. Ann Thorac Surg. 2013 Feb;95(2):775. PubMed PMID: 23336910
  • Chen XJ, Smith PB, Jaggers J, Lodge AJ. Bioprosthetic pulmonary valve replacement: contemporary analysis of a large, single-center series of 170 cases. J Thorac Cardiovasc Surg. 2013 Dec;146(6):1461-6. PubMed PMID: 23122698
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Professional Memberships

  • American Association for Thoracic Surgery, Member
  • American College of Surgeons (ACS), Member
  • Congenital Heart Surgeons Society, Program Committee
  • International Society for Heart & Lung Transplantation, Member
  • Society of Thoracic Surgeons, Workforce on Congenital Heart Disease
  • European Association of Cardiothoracic Surgery, Member
  • World Society of Pediatric Cardiac Surgeons, Member
  • American Academy of Pediatrics (AAP), Specialty Fellow
  • American Heart Assocaition, Member
  • North Carolina Medical Society, Member
  • Southern Thoracic Surgical Association, Member
  • Society of University Surgeons, Member

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Children's Hospital Colorado - Colorado Springs
4090 Briargate Pkwy
Colorado Springs, CO 80920
719-305-1234

Saint Joseph Hospital
1375 E. 19th Avenue
Denver, CO 80218
303-812-2000

Anschutz Inpatient Pavilion 2
12505 E. 16th Ave
Aurora, CO 80045
720-848-0000

Hospital Affiliation
  • Children's Hospital Colorado
  • University of Colorado Hospital
  • Saint Joseph Hospital
Center Affiliations

Specialty Information

Specialties
  • Surgery, Board Certification (1994)
  • Thoracic and Cardiac, Board Certification (1997, 2017)
  • Congenital Cardiac Surgery, Board Certification (2017)
  • Congenital Cardiac surgery, Board Certification (2009)
Conditions & Treatments
  • Heart and Circulation - Heart Valve Diseases
  • Heart and Circulation - Heart Diseases
  • Heart and Circulation - Congenital Heart Disease
  • Surgery - Cardiothoracic Surgery
  • Surgery - Adult Cardiac Surgery
  • Surgery - Heart Transplant Surgery
  • Surgery - Open Heart Surgery
  • Surgery - Cardiothoracic - Congenital Cardiac Surgery
  • Heart and Circulation - Adult Congenital Heart Disease
  • Heart and Circulation
  • Surgery
Clinical Interests
I am interested in complex congenital heart defects in newborns and infants, adult congenital cardiac surgery, pediatric cardiac transplantation, and surgery for Marfan Syndrome.

Care Philosophy
I utilize a multidisciplinary approach to determine the least invasive procedure to solve complex conditions, while ensuring the best possible outcomes.

General Information

Medical Schools:
  • MD, University of Nebraska College of Medicine (1988)
Undergraduate Schools:
  • BS, Chadron State College (NE) (1984)
  • BA, University of Nebraska Medical Center (NE) (1988)
Residency Programs:
  • Oregon Health & Science University, Surgery (1993)
Fellowships:
  • University of Colorado, Thoracic and Cardiac (1996)
  • University of Colorado (Children's Hospital Colorado) Program, Congenital Cardiac Surgery (1996)
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Languages: English
Department: Surgery-Cardiothoracic
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