Dexiang Gao, PhD, MS
Associate Professor, Pediatrics-Endocrinology

Languages: English
Department: Pediatrics-Endocrinology


  • Borges VF, Hu J, Young C, Maggard J, Parris HJ, Gao D, Lyons TR. Semaphorin 7a is a biomarker for recurrence in postpartum breast cancer. NPJ Breast Cancer. 2020;6:56. PubMed PMID: 33088913
  • Morton JJ, Alzofon N, Keysar SB, Chimed TS, Reisinger J, Perrenoud L, Le PN, Nieto C, Gomez K, Miller B, Yeager R, Gao D, Tan AC, Somerset H, Medina T, Wang XJ, Wang JH, Robinson W, Roop DR, Gonzalez R, Jimeno A. Studying immunotherapy resistance in a melanoma autologous humanized mouse xenograft. Mol Cancer Res. 2020 Oct 21. [Epub ahead of print] PubMed PMID: 33087417
  • Boxley PJ, Smith DE, Gao D, Kessler ER, Echalier B, Bernard B, Ormond DR, Lam ET, Kavanagh BD, Flaig TW. Prostate Cancer Central Nervous System Metastasis in a Contemporary Cohort. Clin Genitourin Cancer. 2020 Aug 22. [Epub ahead of print] PubMed PMID: 33069585
  • Weiss JA, Nicklawsky A, Kagihara JA, Gao D, Fisher C, Elias A, Borges VF, Kabos P, Davis SL, Leong S, Eckhardt SG, Diamond JR. Clinical outcomes of breast cancer patients treated in phase I clinical trials at University of Colorado Cancer Center. Cancer Med. 2020 Oct 16. [Epub ahead of print] PubMed PMID: 33063469
  • Chen SMY, Li B, Nicklawsky AG, Krinsky AL, Brunetti T, Woolaver RA, Wang X, Chen Z, Young CD, Gao D, Wang XJ, Wang JH. Deletion of p53 and Hyper-Activation of PIK3CA in Keratin-15( ) Stem Cells Lead to the Development of Spontaneous Squamous Cell Carcinoma. Int J Mol Sci. 2020 Sep 9;21(18). PubMed PMID: 32916850
  • Saltzman AF, Smith DE, Gao D, Ghosh D, Amini A, Aldrink JH, Dasgupta R, Gow KW, Glick RD, Ehrlich PF, Cost NG. Reply to Letter to the Editor. J Pediatr Surg. 2020 Jun 25. [Epub ahead of print] PubMed PMID: 32684283
  • Rusthoven CG, Yamamoto M, Bernhardt D, Smith DE, Gao D, Serizawa T, Yomo S, Aiyama H, Higuchi Y, Shuto T, Akabane A, Sato Y, Niranjan A, Faramand AM, Lunsford LD, McInerney J, Tuanquin LC, Zacharia BE, Chiang V, Singh C, Yu JB, Braunstein S, Mathieu D, Touchette CJ, Lee CC, Yang HC, Aizer AA, Cagney DN, Chan MD, Kondziolka D, Bernstein K, Silverman JS, Grills IS, Siddiqui ZA, Yuan JC, Sheehan JP, Cordeiro D, Nosaki K, Seto T, Deibert CP, Verma V, Day S, Halasz LM, Warnick RE, Trifiletti DM, Palmer JD, Attia A, Li B, Cifarelli CP, Brown PD, Vargo JA, Combs SE, Kessel KA, Rieken S, Patel S, Guckenberger M, Andratschke N, Kavanagh BD, Robin TP. Evaluation of First-line Radiosurgery vs Whole-Brain Radiotherapy for Small Cell Lung Cancer Brain Metastases: The FIRE-SCLC Cohort Study. JAMA Oncol. 2020 Jul 1;6(7):1028-1037. PubMed PMID: 32496550
  • Saltzman AF, Smith DE, Gao D, Cost NG. Lymph node yield in pediatric, adolescent and young adult Renal Cell Carcinoma - How many are enough?. J Pediatr Surg. 2020 Apr 17. [Epub ahead of print] PubMed PMID: 32409174
  • Simons EA, Smith DE, Gao D, Camidge DR. Variation in Toxicity Reporting Methods for Early Phase Lung Cancer Treatment Trials at Oncology Conferences. J Thorac Oncol. 2020 Sep;15(9):1425-1433. PubMed PMID: 32353598
  • Higgins M, Smith DE, Gao D, Wilcox D, Cost NG, Saltzman AF. The impact of age at orchiopexy on testicular cancer outcomes. World J Urol. 2020 Oct;38(10):2531-2536. PubMed PMID: 31781896
  • A Kagihara, JA Weiss, A Nicklawsky, D Gao… - 2020 - AACR Abstract A76: Efficacy of immunotherapy agents in patients with metastatic breast cancer treated in phase I clinical trials
  • Paul Maroni, Elizabeth R. Kessler, Rodrigo Rodrigues-Pessoa, Andrew Nicklawsky, Thomas Flaig, Elaine Lam, Brandon Bernard, James Moore, Kyra Anderson, Dexiang Gao, Komal Raina and Rajesh Agarwal. Abstract CT207: A phase II trial using grape seed extract for prostate cancer patients with non-metastatic PSA progression after local therapy. Cancer Research
  • Ling Lv, Steve Quattlebaum, Dexiang Gao, Yu Cao, Ben Milam, Francis Hall, Derek Smith, Elyse Handley, Sophia Bornstein, Neil Gross, John Song and Shi-Long Lu. Abstract B07: Potential clinical value of methylated microRNAs in saliva-liquid biopsy for surveillance of head and neck squamous cell carcinoma. Clinical Cancer Research
  • Elias, Anthony; Spoelstra, Nicole; Vidal, Gregory A; Sams, Sharon B; ... Gao, Dexiang Phase II trial of fulvestrant plus enzalutamide in ER+/Her2- advanced breast cancer 2020 San Antonio Breast Cancer Symposium December 8-12, 2020
  • Elias, Anthony; Fornier, Monica; Vidal, Gregory A; Sams, Sharon B;...Gao, Dexiang... Phase II randomized trial of fulvestrant with or without enzalutamide in ER+/Her2- primary breast cancer (BC) oster presentation at the 2020 San Antonio Breast Cancer Symposium®, December 8-12, 2020.
  • Samson JM, Ravindran Menon D, Smith DE, Baird E, Kitano T, Gao D, Tan AC, Fujita M. Clinical implications of ALDH1A1 and ALDH1A3 mRNA expression in melanoma subtypes. Chem Biol Interact. 2019 Dec 1;314:108822. PubMed PMID: 31580832
  • Pacheco JM, Gao D, Camidge DR. Extended follow-up on KEYNOTE-024 suggests significant survival benefit for pembrolizumab in patients with PD-L1 =50%, but unanswered questions remain. Ann Transl Med. 2019 Jul;7(Suppl 3):S127. PubMed PMID: 31576334
  • Greenlee CJ, Scholes MA, Gao D, Friedman NR. Obstructive Sleep Apnea and Sleep Position: Does It Matter for Infants With a Cleft Palate?. Cleft Palate Craniofac J. 2019 Aug;56(7):890-895. PubMed PMID: 31282194
  • Saltzman AF, Smith DE, Gao D, Ghosh D, Amini A, Aldrink JH, Dasgupta R, Gow KW, Glick RD, Ehrlich PF, Cost NG. How many lymph nodes are enough? Assessing the adequacy of lymph node yield for staging in favorable histology wilms tumor. J Pediatr Surg. 2019 Nov;54(11):2331-2335. PubMed PMID: 31255328
  • Osborne DG, Domenico J, Luo Y, Reid AL, Amato C, Zhai Z, Gao D, Ziman M, Dinarello CA, Robinson WA, Fujita M. Interleukin-37 is highly expressed in regulatory T cells of melanoma patients and enhanced by melanoma cell secretome. Mol Carcinog. 2019 Sep;58(9):1670-1679. PubMed PMID: 31099111
  • Ruiz AG, Gao D, Ingram DG, Hickey F, Haemer MA, Friedman NR. Does Tonsillectomy Increase Obesity Risk in Children with Down Syndrome?. J Pediatr. 2019 Aug;211:179-184.e1. PubMed PMID: 31084917
  • Friedman NR, Ruiz AG, Gao D, Jensen A, Mitchell RB. Pediatric Obstructive Sleep-Disordered Breathing: Updated Polysomnography Practice Patterns. Otolaryngol Head Neck Surg. 2019 Sep;161(3):529-535. PubMed PMID: 31035864
  • Pham-Danis C, Gehrke S, Danis E, Rozhok AI, Daniels MW, Gao D, Collins C, Paola JTD, D'Alessandro A, DeGregori J. Urea Cycle Sustains Cellular Energetics upon EGFR Inhibition in EGFR-Mutant NSCLC. Mol Cancer Res. 2019 Jun;17(6):1351-1364. PubMed PMID: 30808730
  • Pacheco JM, Gao D, Smith D, Purcell T, Hancock M, Bunn P, Robin T, Liu A, Karam S, Gaspar L, Kavanagh B, Rusthoven C, Aisner D, Doebele R, Camidge DR. Natural History and Factors Associated with Overall Survival in Stage IV ALK-Rearranged Non-Small Cell Lung Cancer. J Thorac Oncol. 2019 Apr;14(4):691-700. PubMed PMID: 30599201
  • Ng TL, Smith DE, Mushtaq R, Patil T, Dimou A, Yang S, Liu Q, Li X, Zhou C, Jones RT, Tu MM, Yan F, Bowman IA, Liu SV, Newkirk S, Bauml J, Doebele RC, Aisner DL, Gao D, Ren S, Camidge DR. ROS1 Gene Rearrangements Are Associated With an Elevated Risk of Peridiagnosis Thromboembolic Events. J Thorac Oncol. 2019 Apr;14(4):596-605. PubMed PMID: 30543838
  • Mark JA, Campbell K, Gao D, Kramer RE. Algorithm to Predict Which Children With Chronic Abdominal Pain Are Low Suspicion for Significant Endoscopic Findings. Clin Pediatr (Phila). 2019 Jan;58(1):79-87. PubMed PMID: 30306797
  • Ng TL, Yu H, Smith DE, Boyle TA, York ER, Leedy S, Gao D, Aisner DL, Van Bokhoven A, Heasley LE, Hirsch FR, Camidge DR. Preselection of Lung Cancer Cases Using FGFR1 mRNA and Gene Copy Number for Treatment With Ponatinib. Clin Lung Cancer. 2019 Jan;20(1):e39-e51. PubMed PMID: 30297175
  • Higgins M, Smith DE, Gao D, Wilcox D, Cost NG, Saltzman AF. The impact of age at orchiopexy on testicular cancer outcomes. World J Urol. 2019 Nov 28. [Epub ahead of print] PubMed PMID: 31781896
  • Tobin RP, Jordan KR, Kapoor P, Spongberg E, Davis D, Vorwald VM, Couts KL, Gao D, Smith DE, Borgers JSW, Robinson S, Amato C, Gonzalez R, Lewis KD, Robinson WA, Borges VF, McCarter MD. IL-6 and IL-8 Are Linked With Myeloid-Derived Suppressor Cell Accumulation and Correlate With Poor Clinical Outcomes in Melanoma Patients. Front Oncol. 2019;9:1223. PubMed PMID: 31781510
  • Keysar SB, Le PN, Miller B, Jackson BC, Eagles JR, Nieto C, Kim J, Tang B, Glogowska MJ, Morton JJ, Padilla-Just N, Gomez K, Warnock E, Reisinger J, Arcaroli JJ, Messersmith WA, Wakefield LM, Gao D, Tan AC, Serracino H, Vasiliou V, Roop DR, Wang XJ, Jimeno A. Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2. J Natl Cancer Inst. 2017 Jan;109(1). PubMed PMID: 27634934
  • Yu H, Batenchuk C, Badzio A, Boyle TA, Czapiewski P, Chan DC, Lu X, Gao D, Ellison K, Kowalewski AA, Rivard CJ, Dziadziuszko R, Zhou C, Hussein M, Richards D, Wilks S, Monte M, Edenfield W, Goldschmidt J, Page R, Ulrich B, Waterhouse D, Close S, Jassem J, Kulig K, Hirsch FR. PD-L1 Expression by Two Complementary Diagnostic Assays and mRNA In Situ Hybridization in Small Cell Lung Cancer. J Thorac Oncol. 2016 Sep 14. [Epub ahead of print] PubMed PMID: 27639678
  • Bourlon MT, Gao D, Trigero S, Clemons JE, Breaker K, Lam ET, Flaig TW. Clinical significance of sunitinib-associated macrocytosis in metastatic renal cell carcinoma. Cancer Med. 2016 Oct 19. [Epub ahead of print] PubMed PMID: 27758076
  • Schade H, Sen S, Neff CP, Freed BM, Gao D, Gutman JA, Palmer BE. Programmed Death 1 Expression on CD4( ) T Cells Predicts Mortality after Allogeneic Stem Cell Transplantation. Biol Blood Marrow Transplant. 2016 Dec;22(12):2172-2179. PubMed PMID: 27519280
  • Helfrich BA, Kim J, Gao D, Chan DC, Zhang Z, Tan AC, Bunn PA Jr. Barasertib (AZD1152), a Small Molecule Aurora B Inhibitor, Inhibits the Growth of SCLC Cell Lines In Vitro and In Vivo. Mol Cancer Ther. 2016 Oct;15(10):2314-2322. PubMed PMID: 27496133
  • Noonan SA, Berry L, Lu X, Gao D, Barón AE, Chesnut P, Sheren J, Aisner DL, Merrick D, Doebele RC, Varella-Garcia M, Camidge DR. Identifying the Appropriate FISH Criteria for Defining MET Copy Number-Driven Lung Adenocarcinoma through Oncogene Overlap Analysis. J Thorac Oncol. 2016 Aug;11(8):1293-304. PubMed PMID: 27262212
  • Quackenbush KS, Bagby S, Tai WM, Messersmith WA, Schreiber A, Greene J, Kim J, Wang G, Purkey A, Pitts TM, Nguyen A, Gao D, Blatchford P, Capasso A, Schuller AG, Eckhardt SG, Arcaroli JJ. The novel tankyrase inhibitor (AZ1366) enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance. Oncotarget. 2016 May 10;7(19):28273-85. PubMed PMID: 27070088
  • Cheng Y, Gao D, Tong T. Bias and variance reduction in estimating the proportion of true-null hypotheses. Biostatistics. 2015 Jan;16(1):189-204. PubMed PMID: 24963010
  • Merrick DT, Gao D, Miller YE, Keith RL, Baron AE, Feser WJ, Kennedy TC, Blatchford P, Braudrick S, Hirsch FR, Heasley LE, Bunn PA Jr, Franklin WA. PERSISTENCE OF BRONCHIAL DYSPLASIA IS ASSOCIATED WITH DEVELOPMENT OF INVASIVE SQUAMOUS CELL CARCINOMA. Cancer Prev Res (Phila). 2015 Nov 5. [Epub ahead of print] PubMed PMID: 26542061
  • Roby BB, Mattingly J, Jensen EL, Gao D, Chan KH. Treatment of Juvenile Recurrent Parotitis of Childhood: An Analysis of Effectiveness. JAMA Otolaryngol Head Neck Surg. 2014 Dec 4. [Epub ahead of print] PubMed PMID: 25474272
  • Wynes MW, Hinz TK, Gao D, Martini M, Marek LA, Ware KE, Edwards MG, Böhm D, Perner S, Helfrich BA, Dziadziuszko R, Jassem J, Wojtylak S, Sejda A, Gozgit JM, Bunn PA Jr, Camidge DR, Tan AC, Hirsch FR, Heasley LE. FGFR1 mRNA and protein expression, not gene copy number, predict FGFR TKI sensitivity across all lung cancer histologies. Clin Cancer Res. 2014 Jun 15;20(12):3299-309. PubMed PMID: 24771645
  • Jindal S, Gao D, Bell P, Albrektsen G, Edgerton SM, Ambrosone CB, Thor AD, Borges VF, Schedin P. Postpartum breast involution reveals regression of secretory lobules mediated by tissue-remodeling. Breast Cancer Res. 2014 Mar 28;16(2):R31. PubMed PMID: 24678808
  • Jordan KR, Amaria RN, Ramirez O, Callihan EB, Gao D, Borakove M, Manthey E, Borges VF, McCarter MD. Myeloid-derived suppressor cells are associated with disease progression and decreased overall survival in advanced-stage melanoma patients. Cancer Immunol Immunother. 2013 Nov;62(11):1711-22. PubMed PMID: 24072401
  • Chan KH, Gao D, Fernandez PG, Kingdom TT, Kumpe DA. Juvenile nasopharyngeal angiofibroma: Vascular determinates for operative complications and tumor recurrence. Laryngoscope. 2013 Aug 8. [Epub ahead of print] PubMed PMID: 23929652
  • Jones TS, Jones EL, Gao D, Pearlman NW, Robinson WA, McCarter M. Management of external ear melanoma: the same or something different?. Am J Surg. 2013 Sep;206(3):307-13. PubMed PMID: 23664431
  • Callihan EB, Gao D, Jindal S, Lyons TR, Manthey E, Edgerton S, Urquhart A, Schedin P, Borges VF. Postpartum diagnosis demonstrates a high risk for metastasis and merits an expanded definition of pregnancy-associated breast cancer. Breast Cancer Res Treat. 2013 Apr;138(2):549-59. PubMed PMID: 23430224
  • Jones EL, Jones TS, Pearlman NW, Gao D, Stovall R, Gajdos C, Kounalakis N, Gonzalez R, Lewis KD, Robinson WA, McCarter MD. Long-term follow-up and survival of patients following a recurrence of melanoma after a negative sentinel lymph node biopsy result. JAMA Surg. 2013 May;148(5):456-61. PubMed PMID: 23325294
  • Freehauf C, Van Hove JL, Gao D, Bernstein L, Thomas JA. Impact of geographic access to care on compliance and metabolic control in phenylketonuria. Mol Genet Metab. 2013 Jan;108(1):13-7. PubMed PMID: 23177662
  • Brandao LN, Winges A, Christoph S, Sather S, Migdall-Wilson J, Schlegel J, McGranahan A, Gao D, Liang X, Deryckere D, Graham DK. Inhibition of MerTK increases chemosensitivity and decreases oncogenic potential in T-cell acute lymphoblastic leukemia. Blood Cancer J. 2013 Jan 25;3:e101. PubMed PMID: 23353780
  • Porter CC, Kim J, Fosmire S, Gearheart CM, van Linden A, Baturin D, Zaberezhnyy V, Patel PR, Gao D, Tan AC, DeGregori J. Integrated genomic analyses identify WEE1 as a critical mediator of cell fate and a novel therapeutic target in acute myeloid leukemia. Leukemia. 2012 Jun;26(6):1266-76. PubMed PMID: 22289989
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Practice Locations

Hospital Affiliation
  • Children's Hospital Colorado

General Information

Languages: English
Department: Pediatrics-Endocrinology