James Burton, MD
Professor, Medicine-Gastroenterology

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Medical School:
  • MD, University of Washington School of Medicine (1997)
Undergraduate School:
  • BA, University of Washington (WA) (1992)
Internship:
  • Strong Memorial Hospital of the University of Rochester Program (1998)
Residency:
  • Strong Memorial Hospital of the University of Rochester Program, Internal Medicine (2000)
Fellowships:
  • Strong Memorial Hospital of the University of Rochester Program, Transplant Hepatology (2001)
  • Oregon Health & Science University, Gastroenterology (2004)
Languages: English
Department: Medicine-Gastroenterology

Professional Titles

  • Medical Director of Liver Transplantation
  • Section Head of Hepatology

Publications

  • Hughes DL, Rice JD, Burton JR, Jin Y, Peterson RA, Ambardekar AV, Pomposelli JJ, Pomfret EA, Kriss MS. Presence of any degree of coronary artery disease among liver transplant candidates is associated with increased rate of post-transplant major adverse cardiac events. Clin Transplant. 2020 Nov;34(11):e14077. PubMed PMID: 32939833
  • Burton JR Jr, Terrault NA, Goldberg DS, Bloom RD, Gilroy R, Heimbach JK, Brown RS Jr, Everson GT, Rubin E, Wiesner R, Pomfret EA. Liver and Kidney Recipient Selection of Hepatitis C Virus Viremic Donors: Meeting Consensus Report From the 2019 Controversies in Transplantation. Transplantation. 2020 Mar;104(3):476-481. PubMed PMID: 31634329
  • Burton JR Jr, Terrault NA, Goldberg DS, Bloom RD, Gilroy R, Heimbach JK, Brown RS Jr, Everson GT, Rubin E, Wiesner R, Pomfret EA. Liver and Kidney Recipient Selection of HCV-Viremic Donors - Meeting Consensus Report from the 2019 Controversies in Transplantation. Transplantation. 2019 Oct 18. [Epub ahead of print] PubMed PMID: 31634329
  • MacBrayne CE, Castillo-Mancilla J, Burton JR Jr, MaWhinney S, Wagner CB, Micke K, Fey J, Huntley RT, Larson B, Bushman LR, Kiser JJ. Small increase in dolutegravir trough, but equivalent total dolutegravir exposure with simeprevir in HIV/HCV seronegative volunteers. J Antimicrob Chemother. 2018 Jan 1;73(1):156-159. PubMed PMID: 29029135
  • Dew MA, Butt Z, Liu Q, Simpson MA, Zee J, Ladner DP, Holtzman S, Smith AR, Pomfret EA, Merion RM, Gillespie BW, Sherker AH, Fisher RA, Olthoff KM, Burton JR Jr, Terrault NA, Fox AN, DiMartini AF. Prevalence and Predictors of Patient-Reported Long-term Mental and Physical Health After Donation in the Adult-to-Adult Living-Donor Liver Transplantation Cohort Study. Transplantation. 2018 Jan;102(1):105-118. PubMed PMID: 28885494
  • Kalra A, Burton JR Jr, Forman LM. Pro: Steroids Can Be Withdrawn After Transplant in Recipients With Autoimmune Hepatitis. Liver Transpl. 2018 Aug;24(8):1109-1112. PubMed PMID: 29923302
  • Rice J, Dodge JL, Bambha KM, Bajaj JS, Reddy KR, Gralla J, Ganapathy D, Mitrani R, Reuter B, Palecki J, Acharya C, Shaw J, Burton JR, Biggins SW. Neutrophil-to-Lymphocyte Ratio Associates Independently With Mortality in Hospitalized Patients With Cirrhosis. Clin Gastroenterol Hepatol. 2018 Nov;16(11):1786-1791.e1. PubMed PMID: 29705264
  • MacBrayne CE, Castillo-Mancilla J, Burton JR Jr, MaWhinney S, Wagner CB, Micke K, Fey J, Huntley RT, Larson B, Bushman LR, Kiser JJ. Small increase in dolutegravir trough, but equivalent total dolutegravir exposure with simeprevir in HIV/HCV seronegative volunteers. J Antimicrob Chemother. 2018 Jan 1;73(1):156-159. PubMed PMID: 29029135
  • Dew MA, Butt Z, Liu Q, Simpson MA, Zee J, Ladner DP, Holtzman S, Smith AR, Pomfret EA, Merion RM, Gillespie BW, Sherker AH, Fisher RA, Olthoff KM, Burton JR Jr, Terrault NA, Fox AN, DiMartini AF. Prevalence and Predictors of Patient-Reported Long-term Mental and Physical Health After Donation in the Adult-to-Adult Living-Donor Liver Transplantation Cohort Study. Transplantation. 2018 Jan;102(1):105-118. PubMed PMID: 28885494
  • O'Leary JG, Fontana RJ, Brown K, Burton JR Jr, Firpi-Morell R, Muir A, O'Brien C, Rabinovitz M, Reddy R, Ryan R, Shprecher A, Villadiego S, Prabhakar A, Brown RS Jr. Efficacy and safety of simeprevir and sofosbuvir with and without ribavirin in subjects with recurrent genotype 1 hepatitis C postorthotopic liver transplant: the randomized GALAXY study. Transpl Int. 2017 Feb;30(2):196-208. PubMed PMID: 27896858
  • O'Leary JG, Fontana RJ, Brown K, Burton JR Jr, Firpi-Morell R, Muir A, O'Brien C, Rabinovitz M, Reddy R, Ryan R, Shprecher A, Villadiego S, Prabhakar A, Brown RS Jr. Efficacy and safety of simeprevir and sofosbuvir with and without ribavirin in subjects with recurrent genotype 1 hepatitis C postorthotopic liver transplant: the randomized GALAXY study. Transpl Int. 2017 Feb;30(2):196-208. PubMed PMID: 27896858
  • Dew MA, DiMartini AF, Ladner DP, Simpson MA, Pomfret EA, Gillespie BW, Merion RM, Zee J, Smith AR, Holtzman S, Sherker AH, Weinrieb R, Fisher RA, Emond JC, Freise CE, Burton JR Jr, Butt Z. Psychosocial Outcomes 3 to 10 Years After Donation in the Adult to Adult Living Donor Liver Transplantation Cohort Study. Transplantation. 2016 Jun;100(6):1257-69. PubMed PMID: 27152918
  • Wilkey BJ, Hanson R, Reece TB, Forman L, Burton JR Jr, Messenger JC, Kim MS, Cleveland JC Jr, Fiegel MJ, Nydam TL, Mandell MS. Transfemoral Transcatheter Aortic Valve Replacement for Mixed Aortic Valve Disease in Child's Class C Liver Disease Prior to Orthotopic Liver Transplantation: A Case Report. Semin Cardiothorac Vasc Anesth. 2016 Jun;20(2):158-62. PubMed PMID: 26620139
  • Brown RS Jr, O'Leary JG, Reddy KR, Kuo A, Morelli GJ, Burton JR Jr, Stravitz RT, Durand C, Di Bisceglie AM, Kwo P, Frenette CT, Stewart TG, Nelson DR, Fried MW, Terrault NA. Interferon-free therapy for genotype 1 hepatitis C in liver transplant recipients: Real-world experience from the hepatitis C therapeutic registry and research network. Liver Transpl. 2016 Jan;22(1):24-33. PubMed PMID: 26519873
  • Ladner DP, Dew MA, Forney S, Gillespie BW, Brown RS Jr, Merion RM, Freise CE, Hayashi PH, Hong JC, Ashworth A, Berg CL, Burton JR Jr, Shaked A, Butt Z. Long-term quality of life after liver donation in the adult to adult living donor liver transplantation cohort study (A2ALL). J Hepatol. 2015 Feb;62(2):346-53. PubMed PMID: 25195558
  • Moorehead KJ, Burton JR Jr, Everson GT, Zheng JH, Kerr BJ, Bushman LR, Wang M, Ju C, Nydam T, Kiser JJ. Intrahepatic antiviral quantification in a patient undergoing orthotopic cadaveric liver transplantation. J Antimicrob Chemother. 2015 Jan;70(1):315-7. PubMed PMID: 25213274
  • Burton JR Jr, O'Leary JG, Verna EC, Saxena V, Dodge JL, Stravitz RT, Levitsky J, Trotter JF, Everson GT, Brown RS Jr, Terrault NA. A US multicenter study of hepatitis C treatment of liver transplant recipients with protease-inhibitor triple therapy. J Hepatol. 2014 Sep;61(3):508-14. PubMed PMID: 24801415
  • Kwo PY, Mantry PS, Coakley E, Te HS, Vargas HE, Brown R Jr, Gordon F, Levitsky J, Terrault NA, Burton JR Jr, Xie W, Setze C, Badri P, Pilot-Matias T, Vilchez RA, Forns X. An interferon-free antiviral regimen for HCV after liver transplantation. N Engl J Med. 2014 Dec 18;371(25):2375-82. PubMed PMID: 25386767
  • Kiser JJ, Burton JR Jr, Everson GT. Drug-drug interactions during antiviral therapy for chronic hepatitis C. Nat Rev Gastroenterol Hepatol. 2013 Oct;10(10):596-606. PubMed PMID: 23817323
  • Biggins SW, Trotter J, Gralla J, Burton JR Jr, Bambha KM, Dodge J, Brocato M, Cheng L, McQueen M, Forman L, Chang M, Kam I, Everson G, Spritz RA, Klintmalm G, Rosen HR. Differential effects of donor and recipient IL28B and DDX58 SNPs on severity of HCV after liver transplantation. J Hepatol. 2013 May;58(5):969-76. PubMed PMID: 23333445
  • Burton JR Jr, Everson GT. Management of the transplant recipient with chronic hepatitis C. Clin Liver Dis. 2013 Feb;17(1):73-91. PubMed PMID: 23177284
  • Hammond KP, Wolfe P, Burton JR Jr, Predhomme JA, Ellis CM, Ray ML, Bushman LR, Kiser JJ. Pharmacokinetic interaction between boceprevir and etravirine in HIV/HCV seronegative volunteers. J Acquir Immune Defic Syndr. 2013 Jan 1;62(1):67-73. PubMed PMID: 23075915
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Practice Locations

UCH - Anschutz Outpatient Pavilion
1635 Aurora Ct
Aurora, CO 80045
720-848-0000

UCH - Anschutz Inpatient Pavilion
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

Hepatology Clinic - Anschutz
1635 Aurora Ct
7th Floor
Aurora, CO 80045
720-848-2280

Hospital Affiliation
  • University of Colorado Hospital

Specialty Information

Specialties
  • Internal Medicine, Board Certification (2000, 2010)
  • Gastroenterology, Board Certification (2004, 2014)
  • Transplant Hepatology, Board Certification (2006, 2016)
Conditions & Treatments
  • Digestive System - Hepatology (Liver Disorders)
  • Digestive System
  • Surgery
  • Surgery - Liver Transplant Surgery
  • Surgery - Living Liver Donation
Clinical Interests
Liver transplantation, living donor liver transplantation, hepatitis C virus infection

Care Philosophy
I am a transplant hepatologist who specializes in the care of patients with acute and chronic liver disease before and after liver transplantation. My goal is to provide outstanding care to patients with complex problems in a way that my patients and their family can understand.

General Information

Medical Schools:
  • MD, University of Washington School of Medicine (1997)
Undergraduate Schools:
  • BA, University of Washington (WA) (1992)
Internships:
  • Strong Memorial Hospital of the University of Rochester Program (1998)
Residency Programs:
  • Strong Memorial Hospital of the University of Rochester Program, Internal Medicine (2000)
Fellowships:
  • Strong Memorial Hospital of the University of Rochester Program, Transplant Hepatology (2001)
  • Oregon Health & Science University, Gastroenterology (2004)
Download CV
Languages: English
Department: Medicine-Gastroenterology
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