Laurence Chan, MD, PhD, MS
Professor, Medicine-Renal Med Diseases/Hypertension

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Languages: English
Department: Medicine-Renal Med Diseases/Hypertension

Research Interests

My research interests include mechanism of allograft rejection and the safety and effectiveness of new therapeutic protocols for kidney transplantation. Application of NMR and other molecular biomarkers in allograft rejection and study of the effects of different immunosuppressive drugs on cellular metabolism.

Publications

  • Weir MR, Pearson TC, Patel A, Peddi VR, Kalil R, Scandling J, Chan L, Baliga P, Melton L, Mulgaonkar S, Waid T, Schaefer H, Youssef N, Anandagoda L, McCollum D, Lawson S, Gordon R. Long-term Follow-up of Kidney Transplant Recipients in the Spare-the-Nephron-Trial. Transplantation. 2017 Jan;101(1):157-165. PubMed PMID: 26950714
  • Modena BD, Kurian SM, Gaber LW, Waalen J, Su AI, Gelbart T, Mondala TS, Head SR, Papp S, Heilman R, Friedewald JJ, Flechner SM, Marsh CL, Sung RS, Shidban H, Chan L, Abecassis MM, Salomon DR. Gene Expression in Biopsies of Acute Rejection and Interstitial Fibrosis/Tubular Atrophy Reveals Highly Shared Mechanisms That Correlate With Worse Long-Term Outcomes. Am J Transplant. 2016 Jul;16(7):1982-98. PubMed PMID: 26990570
  • Cooper JE, Gralla J, Klem P, Chan L, Wiseman AC. High dose intravenous immunoglobulin therapy for donor-specific antibodies in kidney transplant recipients with acute and chronic graft dysfunction. Transplantation. 2014 Jun 27;97(12):1253-9. PubMed PMID: 24937199
  • Langone A, Shihab F, Pankewycz O, Doria C, Wiland A, McCague K, Chan L. Long-term dosing patterns of enteric-coated mycophenolate sodium or mycophenolate mofetil with tacrolimus after renal transplantation. Clin Transplant. 2014 Sep;28(9):961-7. PubMed PMID: 24893821
  • Tsapepas D, Langone A, Chan L, Wiland A, McCague K, Chisholm-Burns M. A longitudinal assessment of adherence with immunosuppressive therapy following kidney transplantation from the Mycophenolic Acid Observational REnal Transplant (MORE) study. Ann Transplant. 2014 Apr 17;19:174-81. PubMed PMID: 24743224
  • Narayanan M, Pankewycz O, Shihab F, Wiland A, McCague K, Chan L. Long-term outcomes in African American kidney transplant recipients under contemporary immunosuppression: a four-yr analysis of the Mycophenolic acid Observational REnal transplant (MORE) study. Clin Transplant. 2014 Feb;28(2):184-91. PubMed PMID: 24372743
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Practice Locations

Transplant Services - Anschutz
1635 Aurora Ct
7th Floor
Aurora, CO 80045
720-848-0005

UCH - Anschutz Inpatient Pavilion
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

UCH - Anschutz Outpatient Pavilion
1635 Aurora Ct
Aurora, CO 80045
720-848-0000

Hospital Affiliation
  • University of Colorado Hospital

Specialty Information

Specialties
  • Nephrology
  • Surgery
Conditions & Treatments
  • Kidneys and Urinary System
  • Kidneys and Urinary System - Kidney Disease
  • Kidneys and Urinary System - Kidney Failure

General Information

Languages: English
Department: Medicine-Renal Med Diseases/Hypertension
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