Fabia Gamboni, PhD
Research Instructor, Biochemistry & Molecular Genetics

Publications

  • Nunns GR, Vigneshwar N, Kelher MR, Stettler GR, Gera L, Reisz JA, D'Alessandro A, Ryon J, Hansen KC, Gamboni F, Moore EE, Peltz ED, Cohen MJ, Jones KL, Sauaia A, Liang X, Banerjee A, Ghasabyan A, Chandler JG, Rodawig S, Jones C, Eitel A, Hom P, Silliman CC. Succinate Activation of SUCNR1 Predisposes Severely Injured Patients to Neutrophil-Mediated ARDS. Ann Surg. 2020 Nov 18. [Epub ahead of print] PubMed PMID: 33214479
  • Jones CL, Stevens BM, Pollyea DA, Culp-Hill R, Reisz JA, Nemkov T, Gehrke S, Gamboni F, Krug A, Winters A, Pei S, Gustafson A, Ye H, Inguva A, Amaya M, Minhajuddin M, Abbott D, Becker MW, DeGregori J, Smith CA, D'Alessandro A, Jordan CT. Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells. Cell Stem Cell. 2020 Nov 5;27(5):748-764.e4. PubMed PMID: 32822582
  • D'Alessandro A, Thomas KA, Stefanoni D, Gamboni F, Shea SM, Reisz JA, Spinella PC. Metabolic phenotypes of standard and cold-stored platelets. Transfusion. 2020 Jun;60 Suppl 3:S96-S106. PubMed PMID: 31880330
  • D'Alessandro A, Thomas KA, Stefanoni D, Gamboni F, Shea SM, Reisz JA, Spinella PC. Metabolic phenotypes of standard and cold-stored platelets. Transfusion. 2019 Dec 27. [Epub ahead of print] PubMed PMID: 31880330
  • Gehrke S, Shah N, Gamboni F, Kamyszek R, Srinivasan AJ, Gray A, Landrigan M, Welsby I, D'Alessandro A. Metabolic impact of red blood cell exchange with rejuvenated red blood cells in sickle cell patients. Transfusion. 2019 Oct;59(10):3102-3112. PubMed PMID: 31385330
  • Paredes RM, Tadaki DK, Sooter A, Gamboni F, Sheppard F. Cryopreservation of human whole blood allows immunophenotyping by flow cytometry up to 30days after cell isolation. J Immunol Methods. 2018 Jan;452:32-38. PubMed PMID: 28927728
  • Marchetti C, Swartzwelter B, Gamboni F, Neff CP, Richter K, Azam T, Carta S, Tengesdal I, Nemkov T, D'Alessandro A, Henry C, Jones GS, Goodrich SA, St Laurent JP, Jones TM, Scribner CL, Barrow RB, Altman RD, Skouras DB, Gattorno M, Grau V, Janciauskiene S, Rubartelli A, Joosten LAB, Dinarello CA. OLT1177, a ß-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation. Proc Natl Acad Sci U S A. 2018 Jan 29. [Epub ahead of print] PubMed PMID: 29378952
  • Mitra S, Schiller D, Anderson C, Gamboni F, D'Alessandro A, Kelher M, Silliman CC, Banerjee A, Jones KL. Hypertonic saline attenuates the cytokine-induced pro-inflammatory signature in primary human lung epithelia. PLoS One. 2017;12(12):e0189536. PubMed PMID: 29253007
  • Kelher MR, McLaughlin NJ, Banerjee A, Elzi DJ, Gamboni F, Khan SY, Meng X, Mitra S, Silliman CC. LysoPCs induce Hck- and PKCd-mediated activation of PKC? causing p47phox phosphorylation and membrane translocation in neutrophils. J Leukoc Biol. 2017 Jan;101(1):261-273. PubMed PMID: 27531930
  • Chapman MP, Moore EE, Moore HB, Gonzalez E, Gamboni F, Chandler JG, Mitra S, Ghasabyan A, Chin TL, Sauaia A, Banerjee A, Silliman CC. Overwhelming tPA release, not PAI-1 degradation, is responsible for hyperfibrinolysis in severely injured trauma patients. J Trauma Acute Care Surg. 2016 Jan;80(1):16-25. PubMed PMID: 26491796
  • Moore HB, Moore EE, Lawson PJ, Gonzalez E, Fragoso M, Morton AP, Gamboni F, Chapman MP, Sauaia A, Banerjee A, Silliman CC. Fibrinolysis shutdown phenotype masks changes in rodent coagulation in tissue injury versus hemorrhagic shock. Surgery. 2015 Aug;158(2):386-92. PubMed PMID: 25979440
  • Wright FL, Gamboni F, Moore EE, Nydam TL, Mitra S, Silliman CC, Banerjee A. Hyperosmolarity invokes distinct anti-inflammatory mechanisms in pulmonary epithelial cells: evidence from signaling and transcription layers. PLoS One. 2014;9(12):e114129. PubMed PMID: 25479425
  • Gamboni F, Escobar GA, Moore EE, Dzieciatkowska M, Hansen KC, Mitra S, Nydam TA, Silliman CC, Banerjee A. Clathrin complexes with the inhibitor kappa B kinase signalosome: imaging the interactome. Physiol Rep. 2014 Jul 1;2(7). PubMed PMID: 24994893
  • Stringham JR, Moore EE, Gamboni F, Harr JN, Fragoso M, Chin TL, Carr CE, Silliman CC, Banerjee A. Mesenteric lymph diversion abrogates 5-lipoxygenase activation in the kidney following trauma and hemorrhagic shock. J Trauma Acute Care Surg. 2014 May;76(5):1214-21. PubMed PMID: 24747451
  • Howard K, Lo KK, Ao L, Gamboni F, Edil BH, Schulick R, Barnett CC Jr. Intercellular adhesion molecule-1 mediates murine colon adenocarcinoma invasion. J Surg Res. 2014 Mar;187(1):19-23. PubMed PMID: 24360118
  • Howard K, Lo KK, Ao L, Gamboni F, Edil BH, Schulick R, Barnett CC Jr. Intercellular adhesion molecule-1 mediates murine colon adenocarcinoma invasion. J Surg Res. 2013 Nov 8. [Epub ahead of print] PubMed PMID: 24360118
  • Bell MT, Puskas F, Agoston VA, Cleveland JC Jr, Freeman KA, Gamboni F, Herson PS, Meng X, Smith PD, Weyant MJ, Fullerton DA, Reece TB. Toll-like receptor 4-dependent microglial activation mediates spinal cord ischemia-reperfusion injury. Circulation. 2013 Sep 10;128(11 Suppl 1):S152-6. PubMed PMID: 24030400
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General Information

Department: Biochemistry & Molecular Genetics
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