Michael Falta, PhD
Instructor, Medicine-Allergy/Clinical Immunology

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Graduate School :
  • PhD, University of Vermont (1994)
Undergraduate School:
  • BA, Hamilton College (NY) (1986)
Department: Medicine-Allergy/Clinical Immunology

Professional Titles

  • Instructor

Research Interests

I have a longstanding interest in determining the role of CD4 T cells in the immunopathology of various autoimmune and pulmonary diseases.

Publications

  • Mitchell AM, Kaiser Y, Falta MT, Munson DJ, Landry LG, Eklund A, Nakayama M, Slansky JE, Grunewald J, Fontenot AP. Shared aß TCR Usage in Lungs of Sarcoidosis Patients with Löfgren's Syndrome. J Immunol. 2017 Oct 1;199(7):2279-2290. PubMed PMID: 28827283
  • Fontenot AP, Falta MT, Kappler JW, Dai S, McKee AS. Beryllium-Induced Hypersensitivity: Genetic Susceptibility and Neoantigen Generation. J Immunol. 2016 Jan 1;196(1):22-7. PubMed PMID: 26685315
  • Falta MT, Tinega AN, Mack DG, Bowerman NA, Crawford F, Kappler JW, Pinilla C, Fontenot AP. Metal-specific CD4( ) T-cell responses induced by beryllium exposure in HLA-DP2 transgenic mice. Mucosal Immunol. 2016 Jan;9(1):218-28. PubMed PMID: 26129650
  • Munson DJ, Egelston CA, Chiotti KE, Parra ZE, Bruno TC, Moore BL, Nakano TA, Simons DL, Jimenez G, Yim JH, Rozanov DV, Falta MT, Fontenot AP, Reynolds PR, Leach SM, Borges VF, Kappler JW, Spellman PT, Lee PP, Slansky JE. Identification of shared TCR sequences from T cells in human breast cancer using emulsion RT-PCR. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8272-7. PubMed PMID: 27307436
  • Clayton GM, Wang Y, Crawford F, Novikov A, Wimberly BT, Kieft JS, Falta MT, Bowerman NA, Marrack P, Fontenot AP, Dai S, Kappler JW. Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell. 2014 Jul 3;158(1):132-42. PubMed PMID: 24995984
  • Mack DG, Falta MT, McKee AS, Martin AK, Simonian PL, Crawford F, Gordon T, Mercer RR, Hoover MD, Marrack P, Kappler JW, Tuder RM, Fontenot AP. Regulatory T cells modulate granulomatous inflammation in an HLA-DP2 transgenic murine model of beryllium-induced disease. Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8553-8. PubMed PMID: 24912188
  • Bowerman NA, Falta MT, Mack DG, Wehrmann F, Crawford F, Mroz MM, Maier LA, Kappler JW, Fontenot AP. Identification of multiple public TCR repertoires in chronic beryllium disease. J Immunol. 2014 May 15;192(10):4571-80. PubMed PMID: 24719461
  • Dai S, Falta MT, Bowerman NA, McKee AS, Fontenot AP. T cell recognition of beryllium. Curr Opin Immunol. 2013 Dec;25(6):775-80. PubMed PMID: 23978481
  • Falta MT, Pinilla C, Mack DG, Tinega AN, Crawford F, Giulianotti M, Santos R, Clayton GM, Wang Y, Zhang X, Maier LA, Marrack P, Kappler JW, Fontenot AP. Identification of beryllium-dependent peptides recognized by CD4 T cells in chronic beryllium disease. J Exp Med. 2013 Jul 1;210(7):1403-18. PubMed PMID: 23797096
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General Information

Graduate Schools:
  • PhD, University of Vermont (1994)
Undergraduate Schools:
  • BA, Hamilton College (NY) (1986)
Department: Medicine-Allergy/Clinical Immunology
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