John Song, MD
Associate Professor, Otolaryngology

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Medical School:
  • MD, New York University School of Medicine (1991)
Undergraduate School:
  • BA, Brown University (RI) (1986)
Internship:
  • UCLA Medical Center Program (1992)
Residency:
  • UCLA Medical Center Program, Chief Resident, Otolaryngology (1997)
Languages: English
Department: Otolaryngology

Professional Titles

  • Associate Professor, Otolaryngology
  • Director of Head & Neck Surgery; Practice Director - Otolaryngology Clinic, University of Colorado Hospital

Recognition & Awards

  • Castle Connolly Top Doctors, Castle Connolly (2018)
    Also awarded in 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013, 2014, 2015, 2016, 2017
  • Marquis Who's Who in America, Marquis (2018)
    Also awarded in 2007, 2008, 2009, 2010, 2011, 2012, 2013, 2014, 2015, 2016, 2017
  • The Best Doctors in America, Best Doctors, Inc. (2018)
    Also awarded in 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013, 2014, 2015, 2016, 2017
  • Newsweek Top Cancer Doctor, Newsweek (2017)
    Also awarded in 2015, 2016
  • Honor Award, American Academy of Otolaryngology - Head & Neck Surgery (2008)

Teaching

  • Associate Professor- Director of Head and Neck Surgery (2002)
    School of Medicine, Otolaryngology

Publications

  • Chen X, Cao Y, Sedhom W, Lu L, Liu Y, Wang H, Oka M, Bornstein S, Said S, Song J, Lu SL. Distinct roles of PIK3CA in the enrichment and maintenance of cancer stem cells in head and neck squamous cell carcinoma. Mol Oncol. 2020 Jan;14(1):139-158. PubMed PMID: 31600013
  • Westrich JA, Vermeer DW, Silva A, Bonney S, Berger JN, Cicchini L, Greer RO, Song JI, Raben D, Slansky JE, Lee JH, Spanos WC, Pyeon D. CXCL14 suppresses human papillomavirus-associated head and neck cancer through antigen-specific CD8( ) T-cell responses by upregulating MHC-I expression. Oncogene. 2019 Nov;38(46):7166-7180. PubMed PMID: 31417179
  • Yang CX, Sedhom W, Song J, Lu SL. The Role of MicroRNAs in Recurrence and Metastasis of Head and Neck Squamous Cell Carcinoma. Cancers (Basel). 2019 Mar 21;11(3). PubMed PMID: 30901831
  • Ludt C, Leppert M, Jones A, Song J, Kuwayama D, Pastula DM, Poisson S. Multiple Strokes Associated With Elongation of the Hyoid Bone. Neurohospitalist. 2018 Jan;8(1):35-37. PubMed PMID: 29276562
  • Ludt C, Leppert M, Jones A, Song J, Kuwayama D, Pastula DM, Poisson S. Multiple Strokes Associated With Elongation of the Hyoid Bone. Neurohospitalist. 2018 Jan;8(1):35-37. PubMed PMID: 29276562
  • Cao Y, Green K, Quattlebaum S, Milam B, Lu L, Gao D, He H, Li N, Gao L, Hall F, Whinery M, Handley E, Ma Y, Xu T, Jin F, Xiao J, Wei M, Smith D, Bornstein S, Gross N, Pyeon D, Song J, Lu SL. Methylated genomic loci encoding microRNA as a biomarker panel in tissue and saliva for head and neck squamous cell carcinoma. Clin Epigenetics. 2018;10:43. PubMed PMID: 29636832
  • Cao Y, Liu H, Gao L, Lu L, Du L, Bai H, Li J, Said S, Wang XJ, Song J, Serkova N, Wei M, Xiao J, Lu SL. Cooperation Between Pten and Smad4 in Murine Salivary Gland Tumor Formation and Progression. Neoplasia. 2018 Aug;20(8):764-774. PubMed PMID: 29958137
  • Thomas CM, Mattingly JK, Hendrickse A, Song JI. Case Report of a Massive Retropharyngeal Goiter Resulting in Laryngeal Compression. A A Case Rep. 2017 Sep 15;9(6):178-181. PubMed PMID: 28542048
  • Bauman JE, Duvvuri U, Gooding WE, Rath TJ, Gross ND, Song J, Jimeno A, Yarbrough WG, Johnson FM, Wang L, Chiosea S, Sen M, Kass J, Johnson JT, Ferris RL, Kim S, Hirsch FR, Ellison K, Flaherty JT, Mills GB, Grandis JR. Randomized, placebo-controlled window trial of EGFR, Src, or combined blockade in head and neck cancer. JCI Insight. 2017 Mar 23;2(6):e90449. PubMed PMID: 28352657
  • Morton JJ, Bird G, Keysar SB, Astling DP, Lyons TR, Anderson RT, Glogowska MJ, Estes P, Eagles JR, Le PN, Gan G, McGettigan B, Fernandez P, Padilla-Just N, Varella-Garcia M, Song JI, Bowles DW, Schedin P, Tan AC, Roop DR, Wang XJ, Refaeli Y, Jimeno A. XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer. Oncogene. 2016 Jan 21;35(3):290-300. PubMed PMID: 25893296
  • Deleyiannis FW, Badeau AM, Leem TH, Song JI. Supercharging and augmenting venous drainage of an anterolateral thigh free flap: options and indications. Plast Reconstr Surg Glob Open. 2014 Apr;2(4):e135. PubMed PMID: 25289328
  • White RA, Neiman JM, Reddi A, Han G, Birlea S, Mitra D, Dionne L, Fernandez P, Murao K, Bian L, Keysar SB, Goldstein NB, Song N, Bornstein S, Han Z, Lu X, Wisell J, Li F, Song J, Lu SL, Jimeno A, Roop DR, Wang XJ. Epithelial stem cell mutations that promote squamous cell carcinoma metastasis. J Clin Invest. 2013 Oct 1;123(10):4390-404. PubMed PMID: 23999427
  • Keysar SB, Astling DP, Anderson RT, Vogler BW, Bowles DW, Morton JJ, Paylor JJ, Glogowska MJ, Le PN, Eagles-Soukup JR, Kako SL, Takimoto SM, Sehrt DB, Umpierrez A, Pittman MA, Macfadden SM, Helber RM, Peterson S, Hausman DF, Said S, Leem TH, Goddard JA, Arcaroli JJ, Messersmith WA, Robinson WA, Hirsch FR, Varella-Garcia M, Raben D, Wang XJ, Song JI, Tan AC, Jimeno A. A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins. Mol Oncol. 2013 Aug;7(4):776-90. PubMed PMID: 23607916
  • Keysar SB, Le PN, Anderson RT, Morton JJ, Bowles DW, Paylor JJ, Vogler BW, Thorburn J, Fernandez P, Glogowska MJ, Takimoto SM, Sehrt DB, Gan GN, Eagles-Soukup JR, Serracino H, Hirsch FR, Lucia MS, Thorburn A, Song JI, Wang XJ, Jimeno A. Hedgehog signaling alters reliance on EGF receptor signaling and mediates anti-EGFR therapeutic resistance in head and neck cancer. Cancer Res. 2013 Jun 1;73(11):3381-92. PubMed PMID: 23576557
  • Keysar SB, Astling DP, Anderson RT, Vogler BW, Bowles DW, Morton JJ, Paylor JJ, Glogowska MJ, Le PN, Eagles-Soukup JR, Kako SL, Takimoto SM, Sehrt DB, Umpierrez A, Pittman MA, Macfadden SM, Helber RM, Peterson S, Hausman DF, Said S, Leem TH, Goddard JA, Arcaroli JJ, Messersmith WA, Robinson WA, Hirsch FR, Varella-Garcia M, Raben D, Wang XJ, Song JI, Tan AC, Jimeno A. A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins. Mol Oncol. 2013 Aug;7(4):776-90. PubMed PMID: 23607916
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Professional Memberships

  • American Academy of Otolaryngology - Head & Neck Surgery, Fellow Member
  • Institute for Hospital Quality, Safety, and Efficiency, Member
  • American Medical Association, Member
  • American Head & Neck Society, Member

Practice Locations

Ear, Nose, & Throat - Anschutz
1635 Aurora Ct
Aurora, CO 80045
720-848-2820

Hospital Affiliation
  • University of Colorado Hospital
  • Children's Hospital Colorado
  • Veterans Affairs Medical Center
  • Denver Health Medical Center

Specialty Information

Specialties
  • Otolaryngology, Board Certification (2002)
  • Institute for Hospital Quality, Safety, and Efficiency (IHQSE), Certificate (0001)
Conditions & Treatments
  • Ear, Nose, and Throat (ENT) - Head and Neck Tumors
  • Ear, Nose, and Throat (ENT)
  • Ear, Nose, and Throat (ENT) - Dysphagia (Trouble Swallowing)
  • Ear, Nose, and Throat (ENT) - Hoarseness
  • Cancers - Cancer Surgery
  • Cancers - Melanoma
  • Cancers - Skin Cancer
  • Cancers - Sarcoma
  • Endocrine System (Hormones) - Thyroid Cancer
  • Surgery - Robotic Surgery
  • Cancers
  • Endocrine System (Hormones)
  • Surgery
  • Cancers - Head and Neck Cancer
Clinical Interests
I am interested in head and neck surgery, skull base surgery, thyroid and parathyroid surgery, swallowing disorders and rehabilitation after head and neck cancer.

General Information

Medical Schools:
  • MD, New York University School of Medicine (1991)
Undergraduate Schools:
  • BA, Brown University (RI) (1986)
Internships:
  • UCLA Medical Center Program (1992)
Residency Programs:
  • UCLA Medical Center Program, Chief Resident, Otolaryngology (1997)
Languages: English
Department: Otolaryngology
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