Stanley Szefler, MD
Professor, Pediatrics-Pulmonary Medicine

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Medical School:
  • MD, State University of New York - Buffalo (1975)
Undergraduate School:
  • BSc, State University of New York at Buffalo (NY) (1971)
Residency:
  • University at Buffalo School of Medicine Program, Pediatrics (1977)
Languages: English
Department: Pediatrics-Pulmonary Medicine

Professional Titles

  • Professor, Pediatrics-Pulmonary Medicine
  • Director - Pediatric Asthma Research Program
Research interests for Patients:
Dr. Szefler's major contributions are directed toward the appropriate use of long-term control therapy in asthma, including the recognition of variability in response to asthma therapy. He has identified biomarkers and asthma characteristics that can be used to predict and thus individualize asthma therapy. Dr. Szefler is the Director of the Pediatric Asthma Research Program and Research Medical Director in the Breathing Institute of the Pediatric Pulmonary Section at Children's Hospital Colorado. He is also Professor of Pediatrics at the University of Colorado Denver School of Medicine. He is also a former member of the Expert Panel for the National Heart, Lung, and Blood Institute's National Asthma Education and Prevention Program on "Guidelines for the Diagnosis and Management of Asthma" and a former member of the Global Initiative for Asthma Science Committee. From 1997 through 2018 he served as Deputy Editor for the Journal of Allergy and Clinical Immunology. He has published more than 500 scientific articles and co-edited books on severe asthma, childhood asthma and pediatric allergy and immunology and personalized medicine. He is the Principal Investigator for the Denver site of the NHLBI AsthmaNet-Pediatrics Section and Co-Principal Investigator for the NHLBI PrecISE Network. For the past thirteen years, he has directed a school-based asthma program for the Denver Public School system funded by the Colorado Department of Public Health and Environment Colorado Cancer, Cardiovascular and Pulmonary Disease Program. This program seeks to define the prevalence and severity of asthma, identify those most significantly affected, and to direct those children to state of the art asthma care. This program also developed a mentorship program for school nurses and was supported by Glaxo Smith Kline in order to set a national standard for school-based asthma management. A recent partnership with CareDOX is intended to provide an asthma module for school medical records.

Teaching

  • Professor (1982)
    School of Medicine, Pediatrics
    My area of interest is pediatric respiratory disease, especially childhood asthma.

Publications

  • Fitzpatrick AM, Bacharier LB, Guilbert TW, Jackson DJ, Szefler SJ, Beigelman A, Cabana MD, Covar R, Holguin F, Lemanske RF Jr, Martinez FD, Morgan W, Phipatanakul W, Pongracic JA, Zeiger RS, Mauger DT. Phenotypes of Recurrent Wheezing in Preschool Children: Identification by Latent Class Analysis and Utility in Prediction of Future Exacerbation. J Allergy Clin Immunol Pract. 2018 Sep 26. [Epub ahead of print] PubMed PMID: 30267890
  • Abrams EM, Becker AB, Szefler SJ. Use of Oral Corticosteroids in the Wheezy Toddler. J Pediatr. 2018 Oct;201:16-20. PubMed PMID: 30251636
  • Szefler SJ, Hoch H, Tuffli M, Gondalia R, Barrett MA, Van Sickle D, Stempel DA. Quantifying beta agonist utilization: occasions or puffs?. J Allergy Clin Immunol Pract. 2018 Sep 12. [Epub ahead of print] PubMed PMID: 30218718
  • Guilbert T, Zeiger RS, Haselkorn T, Iqbal A, Alvarez C, Mink DR, Chipps BE, Szefler SJ. Racial Disparities in Asthma-Related Health Outcomes in Children with Severe/Difficult-to-Treat Asthma. J Allergy Clin Immunol Pract. 2018 Aug 29. [Epub ahead of print] PubMed PMID: 30172020
  • Hollenbach J, Villarreal M, Simoneau T, Langton C, Mitchell H, Flores G, M Cloutier M, Szefler S. Inaccuracy of asthma-related self-reported health-care utilization data compared to Medicaid claims. J Asthma. 2018 Sep 25;:1-4. [Epub ahead of print] PubMed PMID: 30091938
  • Szefler SJ, Cloutier MM, Villarreal M, Hollenbach JP, Gleason M, Haas-Howard C, Vinick C, Calatroni A, Cicutto L, White M, Williams S, McGinn M, Langton C, Shocks D, Mitchell H, Stempel DA. Building Bridges for Asthma Care: Reducing school absence for inner-city children with health disparities. J Allergy Clin Immunol. 2018 Jul 25. [Epub ahead of print] PubMed PMID: 30055181
  • Szefler SJ. Boehringer-Ingelheim Satellite Symposium Choosing the Right Controller Therapy in Pediatric Patients with Asthma. Pediatr Pulmonol. 2018 Jun;53(S1):S171-S173. PubMed PMID: 29906344
  • Messinger AI, Deterding RR, Szefler SJ. Bringing Technology to Day-to-Day Asthma Management. Am J Respir Crit Care Med. 2018 Aug 1;198(3):291-292. PubMed PMID: 29847147
  • Szefler SJ. Dr Elliot F. Ellis: Initiating personalized asthma management in children. Ann Allergy Asthma Immunol. 2018 Jul;121(1):3-6. PubMed PMID: 29758291
  • Chipps BE, Bacharier LB, Farrar JR, Jackson DJ, Murphy KR, Phipatanakul W, Szefler SJ, Teague WG, Zeiger RS. The pediatric asthma yardstick: Practical recommendations for a sustained step-up in asthma therapy for children with inadequately controlled asthma. Ann Allergy Asthma Immunol. 2018 Jun;120(6):559-579.e11. PubMed PMID: 29653238
  • Hoch H, Kempe A, Brinton J, Szefler S. Feasibility of medication monitoring sensors in high risk asthmatic children. J Asthma. 2018 Apr 11;:1-3. [Epub ahead of print] PubMed PMID: 29641374
  • Szefler SJ. Asthma across the lifespan: Time for a paradigm shift. J Allergy Clin Immunol. 2018 Sep;142(3):773-780. PubMed PMID: 29627424
  • Szefler SJ, Chipps B. Challenges in the treatment of asthma in children and adolescents. Ann Allergy Asthma Immunol. 2018 Apr;120(4):382-388. PubMed PMID: 29625664
  • Morris CR, Mauger DT, Suh JH, Phipatanakul W, Sheehan WJ, Moy JN, Paul IM, Szefler SJ, Jackson DJ, Fitzpatrick AM. Glutathione and arginine levels: Predictors for acetaminophen-associated asthma exacerbation?. J Allergy Clin Immunol. 2018 Jul;142(1):308-311.e9. PubMed PMID: 29518418
  • Anderson WC 3rd, Szefler SJ. Controlling the Risk Domain in Pediatric Asthma through Personalized Care. Semin Respir Crit Care Med. 2018 Feb;39(1):36-44. PubMed PMID: 29427984
  • Hamelmann E, Szefler SJ. Efficacy and Safety of Tiotropium in Children and Adolescents. Drugs. 2018 Mar;78(3):327-338. PubMed PMID: 29368127
  • Vrijlandt EJLE, El Azzi G, Vandewalker M, Rupp N, Harper T, Graham L, Szefler SJ, Moroni-Zentgraf P, Sharma A, Vulcu SD, Sigmund R, Chawes B, Engel M, Bisgaard H. Safety and efficacy of tiotropium in children aged 1-5 years with persistent asthmatic symptoms: a randomised, double-blind, placebo-controlled trial. Lancet Respir Med. 2018 Feb;6(2):127-137. PubMed PMID: 29361462
  • Lang JE, Fitzpatrick AM, Mauger DT, Guilbert TW, Jackson DJ, Lemanske RF Jr, Martinez FD, Strunk RC, Zeiger RS, Phipatanakul W, Bacharier LB, Pongracic JA, Holguin F, Cabana MD, Covar RA, Raissy HH, Tang M, Szefler SJ. Overweight/obesity status in preschool children associates with worse asthma but robust improvement on inhaled corticosteroids. J Allergy Clin Immunol. 2017 Dec 8. [Epub ahead of print] PubMed PMID: 29273557
  • Chipps BE, Haselkorn T, Paknis B, Ortiz B, Bleecker ER, Kianifard F, Foreman AJ, Szefler SJ, Zeiger RS. More than a decade follow-up in patients with severe or difficult-to-treat asthma: The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) II. J Allergy Clin Immunol. 2017 Aug 7. [Epub ahead of print] PubMed PMID: 28797732
  • Szefler SJ. Author's response. Ann Allergy Asthma Immunol. 2017 Aug;119(2):194. PubMed PMID: 28801018
  • Chipps BE, Haselkorn T, Paknis B, Ortiz B, Bleecker ER, Kianifard F, Foreman AJ, Szefler SJ, Zeiger RS. More than a decade follow-up in patients with severe or difficult-to-treat asthma: The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) II. J Allergy Clin Immunol. 2017 Aug 7. [Epub ahead of print] PubMed PMID: 28797732
  • Fitzpatrick AM, Jackson DJ, Mauger D, Szefler SJ. Reply. J Allergy Clin Immunol. 2017 Aug 3. [Epub ahead of print] PubMed PMID: 28780972
  • Abrams EM, Szefler SJ, Becker AB. Does inhaled steroid therapy help emerging asthma in early childhood?. Lancet Respir Med. 2017 Aug 2. [Epub ahead of print] PubMed PMID: 28780183
  • Anderson WC 3rd, Gleason MC, Miyazawa N, Szefler SJ. Approaching Current and New Drug Therapies for Pediatric Asthma. Pediatr Clin North Am. 2017 Dec;64(6):1197-1207. PubMed PMID: 29173780
  • Snieder HM, Nickels S, Gleason M, McFarlane A, Szefler SJ, Allison MA. Stakeholder Perspectives on Optimizing Communication in a School-Centered Asthma Program. J Sch Health. 2017 Dec;87(12):941-948. PubMed PMID: 29096412
  • Fitzpatrick AM, Jackson DJ, Mauger D, Szefler SJ. Reply. J Allergy Clin Immunol. 2017 Aug 3. [Epub ahead of print] PubMed PMID: 28780972
  • Abrams EM, Szefler SJ, Becker AB. Does inhaled steroid therapy help emerging asthma in early childhood?. Lancet Respir Med. 2017 Aug 2. [Epub ahead of print] PubMed PMID: 28780183
  • Esquivel A, Busse WW, Calatroni A, Togias AG, Grindle KG, Bochkov YA, Gruchalla RS, Kattan M, Kercsmar CM, Khurana Hershey G, Kim H, Lebeau P, Liu AH, Szefler SJ, Teach SJ, West JB, Wildfire J, Pongracic JA, Gern JE. Effects of Omalizumab on Rhinovirus Infections, Illnesses and Exacerbations of Asthma. Am J Respir Crit Care Med. 2017 Jun 13. [Epub ahead of print] PubMed PMID: 28608756
  • Chipps BE, Lanier B, Milgrom H, Deschildre A, Hedlin G, Szefler SJ, Kattan M, Kianifard F, Ortiz B, Haselkorn T, Iqbal A, Rosén K, Trzaskoma B, Busse WW. Omalizumab in children with uncontrolled allergic asthma: Review of clinical trial and real-world experience. J Allergy Clin Immunol. 2017 May;139(5):1431-1444. PubMed PMID: 28477722
  • Hoch HE, Calatroni A, West JB, Liu AH, Gergen PJ, Gruchalla RS, Khurana Hershey GK, Kercsmar CM, Kim H, Lamm CI, Makhija MM, Mitchell HE, Teach SJ, Wildfire JJ, Busse WW, Szefler SJ. Can we predict fall asthma exacerbations? Validation of the seasonal asthma exacerbation index. J Allergy Clin Immunol. 2017 Feb 24. [Epub ahead of print] PubMed PMID: 28238748
  • Szefler SJ, Murphy K, Harper T 3rd, Boner A, Laki I, Engel M, El Azzi G, Moroni-Zentgraf P, Finnigan H, Hamelmann E. A phase III randomized controlled trial of tiotropium add-on therapy in children with severe symptomatic asthma. J Allergy Clin Immunol. 2017 Feb 9. [Epub ahead of print] PubMed PMID: 28189771
  • Anderson WC 3rd, Apter AJ, Dutmer CM, Searing DA, Szefler SJ. Advances in asthma in 2016: Designing individualized approaches to management. J Allergy Clin Immunol. 2017 Sep;140(3):671-680. PubMed PMID: 28709967
  • Esquivel A, Busse WW, Calatroni A, Togias AG, Grindle KG, Bochkov YA, Gruchalla RS, Kattan M, Kercsmar CM, Khurana Hershey G, Kim H, Lebeau P, Liu AH, Szefler SJ, Teach SJ, West JB, Wildfire J, Pongracic JA, Gern JE. Effects of Omalizumab on Rhinovirus Infections, Illnesses and Exacerbations of Asthma. Am J Respir Crit Care Med. 2017 Jun 13. [Epub ahead of print] PubMed PMID: 28608756
  • Chipps BE, Lanier B, Milgrom H, Deschildre A, Hedlin G, Szefler SJ, Kattan M, Kianifard F, Ortiz B, Haselkorn T, Iqbal A, Rosén K, Trzaskoma B, Busse WW. Omalizumab in children with uncontrolled allergic asthma: Review of clinical trial and real-world experience. J Allergy Clin Immunol. 2017 May;139(5):1431-1444. PubMed PMID: 28477722
  • Hamelmann E, Vogelberg C, Szefler SJ. Reply to 'Can a better patient phenotyping predict the efficacy of tiotropium in asthmatic adolescents?'. Expert Opin Pharmacother. 2017 Jun;18(8):837-838. PubMed PMID: 28399660
  • Hoch HE, Calatroni A, West JB, Liu AH, Gergen PJ, Gruchalla RS, Khurana Hershey GK, Kercsmar CM, Kim H, Lamm CI, Makhija MM, Mitchell HE, Teach SJ, Wildfire JJ, Busse WW, Szefler SJ. Can we predict fall asthma exacerbations? Validation of the seasonal asthma exacerbation index. J Allergy Clin Immunol. 2017 Feb 24. [Epub ahead of print] PubMed PMID: 28238748
  • Bacharier LB, Szefler SJ. Pediatric asthma - moving ahead faster than ever. Curr Opin Allergy Clin Immunol. 2017 Apr;17(2):96-98. PubMed PMID: 28225363
  • Szefler SJ, Murphy K, Harper T 3rd, Boner A, Laki I, Engel M, El Azzi G, Moroni-Zentgraf P, Finnigan H, Hamelmann E. A phase III randomized controlled trial of tiotropium add-on therapy in children with severe symptomatic asthma. J Allergy Clin Immunol. 2017 Feb 9. [Epub ahead of print] PubMed PMID: 28189771
  • Kakumanu S, Antos N, Szefler SJ, Lemanske RF Jr. Building school health partnerships to improve pediatric asthma care: the School-based Asthma Management Program. Curr Opin Allergy Clin Immunol. 2017 Apr;17(2):160-166. PubMed PMID: 28177950
  • Bacharier LB, Szefler SJ. Editorial: moving ahead faster than ever. Curr Opin Allergy Clin Immunol. 2017 Jan 30. [Epub ahead of print] PubMed PMID: 28141627
  • Hamelmann E, Vogelberg C, Szefler SJ. Tiotropium for the treatment of asthma in adolescents. Expert Opin Pharmacother. 2017 Feb;18(3):305-312. PubMed PMID: 28110558
  • Burbank AJ, Szefler SJ. Current and future management of the young child with early onset wheezing. Curr Opin Allergy Clin Immunol. 2017 Apr;17(2):146-152. PubMed PMID: 28092287
  • Nyenhuis SM, Krishnan JA, Berry A, Calhoun WJ, Chinchilli VM, Engle L, Grossman N, Holguin F, Israel E, Kittles RA, Kraft M, Lazarus SC, Lehman EB, Mauger DT, Moy JN, Peters SP, Phipatanakul W, Smith LJ, Sumino K, Szefler SJ, Wechsler ME, Wenzel S, White SR, Ackerman SJ. Race is associated with differences in airway inflammation in patients with asthma. J Allergy Clin Immunol. 2016 Dec 31. [Epub ahead of print] PubMed PMID: 28069248
  • Yang IV, Pedersen BS, Liu AH, O'Connor GT, Pillai D, Kattan M, Misiak RT, Gruchalla R, Szefler SJ, Khurana Hershey GK, Kercsmar C, Richards A, Stevens AD, Kolakowski CA, Makhija M, Sorkness CA, Krouse RZ, Visness C, Davidson EJ, Hennessy CE, Martin RJ, Togias A, Busse WW, Schwartz DA. The nasal methylome and childhood atopic asthma. J Allergy Clin Immunol. 2016 Oct 13. [Epub ahead of print] PubMed PMID: 27745942
  • Iribarren C, Rahmaoui A, Long AA, Szefler SJ, Bradley MS, Carrigan G, Eisner MD, Chen H, Omachi TA, Farkouh ME, Rothman KJ. Cardiovascular and cerebrovascular events among patients receiving omalizumab: Results from EXCELS, a prospective cohort study of moderate-to-severe asthma. J Allergy Clin Immunol. 2016 Sep 14. [Epub ahead of print] PubMed PMID: 27639934
  • Dhami S, Nurmatov U, Agache I, Lau S, Muraro A, Jutel M, Roberts G, Akdis C, Bonini M, Calderon M, Casale T, Cavkaytar O, Cox L, Demoly P, Flood B, Hamelmann E, Izuhara K, Kalayci Ö, Kleine-Tebbe J, Nieto A, Papadopoulos N, Pfaar O, Rosenwasser L, Ryan D, Schmidt-Weber C, Szefler S, Wahn U, van Wijk RG, Wilkinson J, Sheikh A. Erratum to: Allergen immunotherapy for allergic asthma: protocol for a systematic review. Clin Transl Allergy. 2017;7:32. PubMed PMID: 28932386
  • Spahn JD, Malka J, Szefler SJ. Current Application of Exhaled Nitric Oxide in Clinical Practice. J Allergy Clin Immunol. 2016 Sep 21. [Epub ahead of print] PubMed PMID: 27664377
  • Iribarren C, Rahmaoui A, Long AA, Szefler SJ, Bradley MS, Carrigan G, Eisner MD, Chen H, Omachi TA, Farkouh ME, Rothman KJ. Cardiovascular and cerebrovascular events among patients receiving omalizumab: Results from EXCELS, a prospective cohort study of moderate-to-severe asthma. J Allergy Clin Immunol. 2016 Sep 14. [Epub ahead of print] PubMed PMID: 27639934
  • Lemanske RF Jr, Kakumanu S, Shanovich K, Antos N, Cloutier MM, Mazyck D, Phipatanakul W, Schantz S, Szefler S, Vandlik R, Williams P. Creation and implementation of SAMPRO™: A school-based asthma management program. J Allergy Clin Immunol. 2016 Sep;138(3):711-23. PubMed PMID: 27596707
  • Stempel DA, Szefler SJ, Pedersen S, Zeiger RS, Yeakey AM, Lee LA, Liu AH, Mitchell H, Kral KM, Raphiou IH, Prillaman BA, Buaron KS, Yun Kirby S, Pascoe SJ. Safety of Adding Salmeterol to Fluticasone Propionate in Children with Asthma. N Engl J Med. 2016 Sep 1;375(9):840-9. PubMed PMID: 27579634
  • Sheehan WJ, Mauger DT, Paul IM, Moy JN, Boehmer SJ, Szefler SJ, Fitzpatrick AM, Jackson DJ, Bacharier LB, Cabana MD, Covar R, Holguin F, Lemanske RF Jr, Martinez FD, Pongracic JA, Beigelman A, Baxi SN, Benson M, Blake K, Chmiel JF, Daines CL, Daines MO, Gaffin JM, Gentile DA, Gower WA, Israel E, Kumar HV, Lang JE, Lazarus SC, Lima JJ, Ly N, Marbin J, Morgan WJ, Myers RE, Olin JT, Peters SP, Raissy HH, Robison RG, Ross K, Sorkness CA, Thyne SM, Wechsler ME, Phipatanakul W. Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma. N Engl J Med. 2016 Aug 18;375(7):619-30. PubMed PMID: 27532828
  • Liu AH, Anderson WC 3rd, Dutmer CM, Searing DA, Szefler SJ. Advances in asthma 2015: Across the lifespan. J Allergy Clin Immunol. 2016 Aug;138(2):397-404. PubMed PMID: 27497278
  • Federico MJ, Hoch HE, Anderson WC 3rd, Spahn JD, Szefler SJ. Asthma Management for Children: Risk Identification and Prevention. Adv Pediatr. 2016 Aug;63(1):103-26. PubMed PMID: 27426897
  • McGeachie MJ, Yates KP, Zhou X, Guo F, Sternberg AL, Van Natta ML, Wise RA, Szefler SJ, Sharma S, Kho AT, Cho MH, Croteau-Chonka DC, Castaldi PJ, Jain G, Sanyal A, Zhan Y, Lajoie BR, Dekker J, Stamatoyannopoulos J, Covar RA, Zeiger RS, Adkinson NF, Williams PV, Kelly HW, Grasemann H, Vonk JM, Koppelman GH, Postma DS, Raby BA, Houston I, Lu Q, Fuhlbrigge AL, Tantisira KG, Silverman EK, Tonascia J, Strunk RC, Weiss ST. Genetics and Genomics of Longitudinal Lung Function Patterns in Asthmatics. Am J Respir Crit Care Med. 2016 Jul 1. [Epub ahead of print] PubMed PMID: 27367781
  • Liptzin DR, Gleason MC, Cicutto LC, Cleveland CL, Shocks DJ, White MK, Faino AV, Szefler SJ. Developing, Implementing, and Evaluating a School-Centered Asthma Program: Step-Up Asthma Program. J Allergy Clin Immunol Pract. 2016 Sep-Oct;4(5):972-979.e1. PubMed PMID: 27283054
  • McGeachie MJ, Yates KP, Zhou X, Guo F, Sternberg AL, Van Natta ML, Wise RA, Szefler SJ, Sharma S, Kho AT, Cho MH, Croteau-Chonka DC, Castaldi PJ, Jain G, Sanyal A, Zhan Y, Lajoie BR, Dekker J, Stamatoyannopoulos J, Covar RA, Zeiger RS, Adkinson NF, Williams PV, Kelly HW, Grasemann H, Vonk JM, Koppelman GH, Postma DS, Raby BA, Houston I, Lu Q, Fuhlbrigge AL, Tantisira KG, Silverman EK, Tonascia J, Weiss ST, Strunk RC. Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma. N Engl J Med. 2016 May 12;374(19):1842-52. PubMed PMID: 27168434
  • Yang IV, Pedersen BS, Liu AH, O'Connor GT, Teach SJ, Kattan M, Misiak RT, Gruchalla R, Steinbach SF, Szefler SJ, Gill MA, Calatroni A, David G, Hennessy CE, Davidson EJ, Gergen P, Togias A, Busse WW, Schwartz DA. DNA Methylation Changes in Nasal Epithelia Are Associated with Allergic Asthma in the Inner City. Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S99-S100. PubMed PMID: 27027970
  • Kraft M, Gerber AN, Szefler SJ, Wechsler ME. Introduction to the 58th Annual Thomas L. Petty Aspen Lung Conference: Asthma 2015: Mechanisms to Personalized Medicine. Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S23-4. PubMed PMID: 27027947
  • Dunn R, Szefler SJ. Severe Asthma in Pediatric Patients. Pathophysiology and Unmet Needs. Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S103-4. PubMed PMID: 27027942
  • Hamelmann E, Bateman ED, Vogelberg C, Szefler SJ, Vandewalker M, Moroni-Zentgraf P, Avis M, Unseld A, Engel M, Boner AL. Tiotropium add-on therapy in adolescents with moderate asthma: A 1-year randomized controlled trial. J Allergy Clin Immunol. 2016 Aug;138(2):441-450.e8. PubMed PMID: 26960245
  • Szefler SJ. Examining causes of the urban (inner city) asthma epidemic: Implementing new management strategies. Allergy Asthma Proc. 2016 Jan-Feb;37(1):4-8. PubMed PMID: 26831839
  • Cicutto L, Shocks D, Gleason M, Haas-Howard C, White M, Szefler SJ. Creating District Readiness for Implementing Evidence-Based School-Centered Asthma Programs: Denver Public Schools as a Case Study. NASN Sch Nurse. 2016 Mar;31(2):112-8. PubMed PMID: 26822131
  • Hoch HE, Szefler SJ. Intermittent steroid inhalation for the treatment of childhood asthma. Expert Rev Clin Immunol. 2016;12(2):183-94. PubMed PMID: 26561351
  • Abrams EM, Szefler SJ, Becker AB. Effect of asthma therapies on the natural course of asthma. Ann Allergy Asthma Immunol. 2016 Dec;117(6):627-633. PubMed PMID: 28073701
  • Carr WW, Szefler SJ. Inhaled corticosteroids: Ocular safety and the hypothalamic-pituitary-adrenal axis. Ann Allergy Asthma Immunol. 2016 Dec;117(6):589-594. PubMed PMID: 27979014
  • Stempel DA, Szefler SJ, Pascoe SJ. Salmeterol and Fluticasone Propionate in Children with Asthma. N Engl J Med. 2016 Dec 1;375(22):e46. PubMed PMID: 27959746
  • Fitzpatrick AM, Jackson DJ, Mauger DT, Boehmer SJ, Phipatanakul W, Sheehan WJ, Moy JN, Paul IM, Bacharier LB, Cabana MD, Covar R, Holguin F, Lemanske RF Jr, Martinez FD, Pongracic JA, Beigelman A, Baxi SN, Benson M, Blake K, Chmiel JF, Daines CL, Daines MO, Gaffin JM, Gentile DA, Gower WA, Israel E, Kumar HV, Lang JE, Lazarus SC, Lima JJ, Ly N, Marbin J, Morgan W, Myers RE, Olin JT, Peters SP, Raissy HH, Robison RG, Ross K, Sorkness CA, Thyne SM, Szefler SJ. Individualized therapy for persistent asthma in young children. J Allergy Clin Immunol. 2016 Dec;138(6):1608-1618.e12. PubMed PMID: 27777180
  • Liptzin DR, Szefler SJ. Evolution of Asthma Self-Management Programs in Adolescents: From the Crisis Plan to Facebook. J Pediatr. 2016 Oct 10. PubMed PMID: 27745749
  • Gleason M, Cicutto L, Haas-Howard C, Raleigh BM, Szefler SJ. Leveraging Partnerships: Families, Schools, and Providers Working Together to Improve Asthma Management. Curr Allergy Asthma Rep. 2016 Oct;16(10):74. PubMed PMID: 27709456
  • Spahn JD, Malka J, Szefler SJ. Current Application of Exhaled Nitric Oxide in Clinical Practice. J Allergy Clin Immunol. 2016 Sep 21. [Epub ahead of print] PubMed PMID: 27664377
  • Lemanske RF Jr, Kakumanu S, Shanovich K, Antos N, Cloutier MM, Mazyck D, Phipatanakul W, Schantz S, Szefler S, Vandlik R, Williams P. Creation and implementation of SAMPRO™: A school-based asthma management program. J Allergy Clin Immunol. 2016 Sep;138(3):711-23. PubMed PMID: 27596707
  • Stempel DA, Szefler SJ, Pedersen S, Zeiger RS, Yeakey AM, Lee LA, Liu AH, Mitchell H, Kral KM, Raphiou IH, Prillaman BA, Buaron KS, Yun Kirby S, Pascoe SJ. Safety of Adding Salmeterol to Fluticasone Propionate in Children with Asthma. N Engl J Med. 2016 Sep 1;375(9):840-9. PubMed PMID: 27579634
  • Sheehan WJ, Mauger DT, Paul IM, Moy JN, Boehmer SJ, Szefler SJ, Fitzpatrick AM, Jackson DJ, Bacharier LB, Cabana MD, Covar R, Holguin F, Lemanske RF Jr, Martinez FD, Pongracic JA, Beigelman A, Baxi SN, Benson M, Blake K, Chmiel JF, Daines CL, Daines MO, Gaffin JM, Gentile DA, Gower WA, Israel E, Kumar HV, Lang JE, Lazarus SC, Lima JJ, Ly N, Marbin J, Morgan WJ, Myers RE, Olin JT, Peters SP, Raissy HH, Robison RG, Ross K, Sorkness CA, Thyne SM, Wechsler ME, Phipatanakul W. Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma. N Engl J Med. 2016 Aug 18;375(7):619-30. PubMed PMID: 27532828
  • Liu AH, Anderson WC 3rd, Dutmer CM, Searing DA, Szefler SJ. Advances in asthma 2015: Across the lifespan. J Allergy Clin Immunol. 2016 Aug;138(2):397-404. PubMed PMID: 27497278
  • Federico MJ, Hoch HE, Anderson WC 3rd, Spahn JD, Szefler SJ. Asthma Management for Children: Risk Identification and Prevention. Adv Pediatr. 2016 Aug;63(1):103-26. PubMed PMID: 27426897
  • McGeachie MJ, Yates KP, Zhou X, Guo F, Sternberg AL, Van Natta ML, Wise RA, Szefler SJ, Sharma S, Kho AT, Cho MH, Croteau-Chonka DC, Castaldi PJ, Jain G, Sanyal A, Zhan Y, Lajoie BR, Dekker J, Stamatoyannopoulos J, Covar RA, Zeiger RS, Adkinson NF, Williams PV, Kelly HW, Grasemann H, Vonk JM, Koppelman GH, Postma DS, Raby BA, Houston I, Lu Q, Fuhlbrigge AL, Tantisira KG, Silverman EK, Tonascia J, Strunk RC, Weiss ST. Genetics and Genomics of Longitudinal Lung Function Patterns in Asthmatics. Am J Respir Crit Care Med. 2016 Jul 1. [Epub ahead of print] PubMed PMID: 27367781
  • Liptzin DR, Gleason MC, Cicutto LC, Cleveland CL, Shocks DJ, White MK, Faino AV, Szefler SJ. Developing, Implementing, and Evaluating a School-Centered Asthma Program: Step-Up Asthma Program. J Allergy Clin Immunol Pract. 2016 Sep-Oct;4(5):972-979.e1. PubMed PMID: 27283054
  • McGeachie MJ, Yates KP, Zhou X, Guo F, Sternberg AL, Van Natta ML, Wise RA, Szefler SJ, Sharma S, Kho AT, Cho MH, Croteau-Chonka DC, Castaldi PJ, Jain G, Sanyal A, Zhan Y, Lajoie BR, Dekker J, Stamatoyannopoulos J, Covar RA, Zeiger RS, Adkinson NF, Williams PV, Kelly HW, Grasemann H, Vonk JM, Koppelman GH, Postma DS, Raby BA, Houston I, Lu Q, Fuhlbrigge AL, Tantisira KG, Silverman EK, Tonascia J, Weiss ST, Strunk RC. Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma. N Engl J Med. 2016 May 12;374(19):1842-52. PubMed PMID: 27168434
  • Yang IV, Pedersen BS, Liu AH, O'Connor GT, Teach SJ, Kattan M, Misiak RT, Gruchalla R, Steinbach SF, Szefler SJ, Gill MA, Calatroni A, David G, Hennessy CE, Davidson EJ, Gergen P, Togias A, Busse WW, Schwartz DA. DNA Methylation Changes in Nasal Epithelia Are Associated with Allergic Asthma in the Inner City. Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S99-S100. PubMed PMID: 27027970
  • Kraft M, Gerber AN, Szefler SJ, Wechsler ME. Introduction to the 58th Annual Thomas L. Petty Aspen Lung Conference: Asthma 2015: Mechanisms to Personalized Medicine. Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S23-4. PubMed PMID: 27027947
  • Dunn R, Szefler SJ. Severe Asthma in Pediatric Patients. Pathophysiology and Unmet Needs. Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S103-4. PubMed PMID: 27027942
  • Hamelmann E, Bateman ED, Vogelberg C, Szefler SJ, Vandewalker M, Moroni-Zentgraf P, Avis M, Unseld A, Engel M, Boner AL. Tiotropium add-on therapy in adolescents with moderate asthma: A 1-year randomized controlled trial. J Allergy Clin Immunol. 2016 Aug;138(2):441-450.e8. PubMed PMID: 26960245
  • Szefler SJ. Examining causes of the urban (inner city) asthma epidemic: Implementing new management strategies. Allergy Asthma Proc. 2016 Jan-Feb;37(1):4-8. PubMed PMID: 26831839
  • Cicutto L, Shocks D, Gleason M, Haas-Howard C, White M, Szefler SJ. Creating District Readiness for Implementing Evidence-Based School-Centered Asthma Programs: Denver Public Schools as a Case Study. NASN Sch Nurse. 2016 Mar;31(2):112-8. PubMed PMID: 26822131
  • Hoch HE, Szefler SJ. Intermittent steroid inhalation for the treatment of childhood asthma. Expert Rev Clin Immunol. 2016;12(2):183-94. PubMed PMID: 26561351
  • Teach SJ, Gill MA, Togias A, Sorkness CA, Arbes SJ Jr, Calatroni A, Wildfire JJ, Gergen PJ, Cohen RT, Pongracic JA, Kercsmar CM, Khurana Hershey GK, Gruchalla RS, Liu AH, Zoratti EM, Kattan M, Grindle KA, Gern JE, Busse WW, Szefler SJ. Preseasonal treatment with either omalizumab or an inhaled corticosteroid boost to prevent fall asthma exacerbations. J Allergy Clin Immunol. 2015 Oct 23. [Epub ahead of print] PubMed PMID: 26518090
  • Vogelberg C, Moroni-Zentgraf P, Leonaviciute-Klimantaviciene M, Sigmund R, Hamelmann E, Engel M, Szefler S. Erratum to: A randomised dose-ranging study of tiotropium Respimat® in children with symptomatic asthma despite inhaled corticosteroids. Respir Res. 2015 Oct 20;16:128. PubMed PMID: 26487277
  • Leung DY, Szefler SJ. The Editors' Choice. J Allergy Clin Immunol. 2015 Oct;136(4):872-3. PubMed PMID: 26449800
  • Leung DY, Szefler SJ. The Editors' Choice. J Allergy Clin Immunol. 2015 Sep;136(3):569-70. PubMed PMID: 26343940
  • Anderson WC 3rd, Szefler SJ. New and future strategies to improve asthma control in children. J Allergy Clin Immunol. 2015 Oct;136(4):848-59. PubMed PMID: 26318072
  • Levy BD, Noel PJ, Freemer MM, Cloutier MM, Georas SN, Jarjour NN, Ober C, Woodruff PG, Barnes KC, Bender BG, Camargo CA Jr, Chupp GL, Denlinger LC, Fahy JV, Fitzpatrick AM, Fuhlbrigge A, Gaston BM, Hartert TV, Kolls JK, Lynch SV, Moore WC, Morgan WJ, Nadeau KC, Ownby DR, Solway J, Szefler SJ, Wenzel SE, Wright RJ, Smith RA, Erzurum SC. Future Research Directions in Asthma: An NHLBI Working Group Report. Am J Respir Crit Care Med. 2015 Aug 25. [Epub ahead of print] PubMed PMID: 26305520
  • Reddel HK, Bateman ED, Becker A, Boulet LP, Cruz AA, Drazen JM, Haahtela T, Hurd SS, Inoue H, de Jongste JC, Lemanske RF Jr, Levy ML, O'Byrne PM, Paggiaro P, Pedersen SE, Pizzichini E, Soto-Quiroz M, Szefler SJ, Wong GW, FitzGerald JM. A summary of the new GINA strategy: a roadmap to asthma control. Eur Respir J. 2015 Sep;46(3):622-39. PubMed PMID: 26206872
  • Dunn RM, Lehman E, Chinchilli VM, Martin RJ, Boushey HA, Israel E, Kraft M, Lazarus SC, Lemanske RF, Lugogo NL, Peters SP, Sorkness CA, Szefler S, Wechsler ME. Impact of Age and Sex on Response to Asthma Therapy. Am J Respir Crit Care Med. 2015 Sep 1;192(5):551-8. PubMed PMID: 26068329
  • Brand PL, Mäkelä MJ, Szefler SJ, Frischer T, Price D. Monitoring asthma in childhood: symptoms, exacerbations and quality of life. Eur Respir Rev. 2015 Jun;24(136):187-93. PubMed PMID: 26028631
  • Meltzer LJ, Faino A, Szefler SJ, Strand M, Gelfand EW, Beebe DW. Experimentally manipulated sleep duration in adolescents with asthma: Feasibility and preliminary findings. Pediatr Pulmonol. 2015 Apr 14. [Epub ahead of print] PubMed PMID: 25872769
  • Vogelberg C, Moroni-Zentgraf P, Leonaviciute-Klimantaviciene M, Sigmund R, Hamelmann E, Engel M, Szefler S. A randomised dose-ranging study of tiotropium Respimat® in children with symptomatic asthma despite inhaled corticosteroids. Respir Res. 2015 Feb 7;16:20. PubMed PMID: 25851298
  • Teach SJ, Gergen PJ, Szefler SJ, Mitchell HE, Calatroni A, Wildfire J, Bloomberg GR, Kercsmar CM, Liu AH, Makhija MM, Matsui E, Morgan W, O'Connor G, Busse WW. Seasonal risk factors for asthma exacerbations among inner-city children. J Allergy Clin Immunol. 2015 Jun;135(6):1465-73.e5. PubMed PMID: 25794658
  • Gerald JK, Gerald LB, Vasquez MM, Morgan WJ, Boehmer SJ, Lemanske RF Jr, Mauger DT, Strunk RC, Szefler SJ, Zeiger RS, Bacharier LB, Bade E, Covar RA, Guilbert TW, Heidarian-Raissy H, Kelly HW, Malka-Rais J, Sorkness CA, Taussig LM, Chinchilli VM, Martinez FD. Markers of Differential Response to Inhaled Corticosteroid Treatment Among Children with Mild Persistent Asthma. J Allergy Clin Immunol Pract. 2015 Jul-Aug;3(4):540-6.e3. PubMed PMID: 25783161
  • Yang IV, Pedersen BS, Liu A, O'Connor GT, Teach SJ, Kattan M, Misiak RT, Gruchalla R, Steinbach SF, Szefler SJ, Gill MA, Calatroni A, David G, Hennessy CE, Davidson EJ, Zhang W, Gergen P, Togias A, Busse WW, Schwartz DA. DNA methylation and childhood asthma in the inner city. J Allergy Clin Immunol. 2015 Jul;136(1):69-80. PubMed PMID: 25769910
  • Pijnenburg MW, Baraldi E, Brand PL, Carlsen KH, Eber E, Frischer T, Hedlin G, Kulkarni N, Lex C, Mäkelä MJ, Mantzouranis E, Moeller A, Pavord I, Piacentini G, Price D, Rottier BL, Saglani S, Sly PD, Szefler SJ, Tonia T, Turner S, Wooler E, Lødrup Carlsen KC. Monitoring asthma in children. Eur Respir J. 2015 Apr;45(4):906-25. PubMed PMID: 25745042
  • Szefler SJ. Advances in pediatric asthma in 2014: Moving toward a population health perspective. J Allergy Clin Immunol. 2015 Mar;135(3):644-52. PubMed PMID: 25649079
  • Szefler SJ. Monitoring and adherence in asthma management. Lancet Respir Med. 2015 Mar;3(3):175-6. PubMed PMID: 25617214
  • Wang Y, Tong C, Wang Z, Wang Z, Mauger D, Tantisira KG, Israel E, Szefler SJ, Chinchilli VM, Boushey HA, Lazarus SC, Lemanske RF, Wu R. Pharmacodynamic genome-wide association study identifies new responsive loci for glucocorticoid intervention in asthma. Pharmacogenomics J. 2015 Oct;15(5):422-9. PubMed PMID: 25601762
  • Israel E, Lasky-Su J, Markezich A, Damask A, Szefler SJ, Schuemann B, Klanderman B, Sylvia J, Kazani S, Wu R, Martinez F, Boushey HA, Chinchilli VM, Mauger D, Weiss ST, Tantisira KG. Genome-wide association study of short-acting ß2-agonists. A novel genome-wide significant locus on chromosome 2 near ASB3. Am J Respir Crit Care Med. 2015 Mar 1;191(5):530-7. PubMed PMID: 25562107
  • Zemanick ET, Wagner BD, Robertson CE, Stevens MJ, Szefler SJ, Accurso FJ, Sagel SD, Harris JK. Assessment of Airway Microbiota and Inflammation in Cystic Fibrosis Using Multiple Sampling Methods. Ann Am Thorac Soc. 2014 Dec 4. [Epub ahead of print] PubMed PMID: 25474078
  • Pijnenburg MW, Szefler S. Personalized medicine in children with asthma. Paediatr Respir Rev. 2014 Nov 8. [Epub ahead of print] PubMed PMID: 25458797
  • Long A, Rothman K, Chen H, Carrigan G, Szefler S, EXCELS study authors. Reply. J Allergy Clin Immunol. 2014 Oct 29. [Epub ahead of print] PubMed PMID: 25441293
  • Dhami S, Nurmatov U, Agache I, Lau S, Muraro A, Jutel M, Roberts G, Akdis C, Bonini M, Calderon M, Casale T, Cavkaytar O, Cox L, Demoly P, Flood B, Hamelmann E, Izuhara K, Kalayci Ö, Kleine-Tebbe J, Nieto A, Papadopoulos N, Pfaar O, Rosenwasser L, Ryan D, Schmidt-Weber C, Szefler S, Wahn U, van Wijk RG, Wilkinson J, Sheikh A. Allergen immunotherapy for allergic asthma: protocol for a systematic review. Clin Transl Allergy. 2015;6:5. PubMed PMID: 26862389
  • Bender BG, Krishnan JA, Chambers DA, Cloutier MM, Riekert KA, Rand CS, Schatz M, Thomson CC, Wilson SR, Apter A, Carson SS, George M, Gerald JK, Gerald L, Goss CH, Okelo SO, Mularski RA, Nguyen HQ, Patel MR, Szefler SJ, Weiss CH, Wilson KC, Freemer M. American Thoracic Society and National Heart, Lung, and Blood Institute Implementation Research Workshop Report. Ann Am Thorac Soc. 2015 Dec;12(12):S213-21. PubMed PMID: 26653201
  • Bacharier LB, Guilbert TW, Mauger DT, Boehmer S, Beigelman A, Fitzpatrick AM, Jackson DJ, Baxi SN, Benson M, Burnham CA, Cabana M, Castro M, Chmiel JF, Covar R, Daines M, Gaffin JM, Gentile DA, Holguin F, Israel E, Kelly HW, Lazarus SC, Lemanske RF Jr, Ly N, Meade K, Morgan W, Moy J, Olin T, Peters SP, Phipatanakul W, Pongracic JA, Raissy HH, Ross K, Sheehan WJ, Sorkness C, Szefler SJ, Teague WG, Thyne S, Martinez FD. Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Clinical Trial. JAMA. 2015 Nov 17;314(19):2034-44. PubMed PMID: 26575060
  • Teach SJ, Gill MA, Togias A, Sorkness CA, Arbes SJ Jr, Calatroni A, Wildfire JJ, Gergen PJ, Cohen RT, Pongracic JA, Kercsmar CM, Khurana Hershey GK, Gruchalla RS, Liu AH, Zoratti EM, Kattan M, Grindle KA, Gern JE, Busse WW, Szefler SJ. Preseasonal treatment with either omalizumab or an inhaled corticosteroid boost to prevent fall asthma exacerbations. J Allergy Clin Immunol. 2015 Oct 23. [Epub ahead of print] PubMed PMID: 26518090
  • Vogelberg C, Moroni-Zentgraf P, Leonaviciute-Klimantaviciene M, Sigmund R, Hamelmann E, Engel M, Szefler S. Erratum to: A randomised dose-ranging study of tiotropium Respimat® in children with symptomatic asthma despite inhaled corticosteroids. Respir Res. 2015 Oct 20;16:128. PubMed PMID: 26487277
  • Anderson WC 3rd, Szefler SJ. New and future strategies to improve asthma control in children. J Allergy Clin Immunol. 2015 Oct;136(4):848-59. PubMed PMID: 26318072
  • Levy BD, Noel PJ, Freemer MM, Cloutier MM, Georas SN, Jarjour NN, Ober C, Woodruff PG, Barnes KC, Bender BG, Camargo CA Jr, Chupp GL, Denlinger LC, Fahy JV, Fitzpatrick AM, Fuhlbrigge A, Gaston BM, Hartert TV, Kolls JK, Lynch SV, Moore WC, Morgan WJ, Nadeau KC, Ownby DR, Solway J, Szefler SJ, Wenzel SE, Wright RJ, Smith RA, Erzurum SC. Future Research Directions in Asthma: An NHLBI Working Group Report. Am J Respir Crit Care Med. 2015 Aug 25. [Epub ahead of print] PubMed PMID: 26305520
  • Reddel HK, Bateman ED, Becker A, Boulet LP, Cruz AA, Drazen JM, Haahtela T, Hurd SS, Inoue H, de Jongste JC, Lemanske RF Jr, Levy ML, O'Byrne PM, Paggiaro P, Pedersen SE, Pizzichini E, Soto-Quiroz M, Szefler SJ, Wong GW, FitzGerald JM. A summary of the new GINA strategy: a roadmap to asthma control. Eur Respir J. 2015 Sep;46(3):622-39. PubMed PMID: 26206872
  • Dunn RM, Lehman E, Chinchilli VM, Martin RJ, Boushey HA, Israel E, Kraft M, Lazarus SC, Lemanske RF, Lugogo NL, Peters SP, Sorkness CA, Szefler S, Wechsler ME. Impact of Age and Sex on Response to Asthma Therapy. Am J Respir Crit Care Med. 2015 Sep 1;192(5):551-8. PubMed PMID: 26068329
  • Brand PL, Mäkelä MJ, Szefler SJ, Frischer T, Price D. Monitoring asthma in childhood: symptoms, exacerbations and quality of life. Eur Respir Rev. 2015 Jun;24(136):187-93. PubMed PMID: 26028631
  • Meltzer LJ, Faino A, Szefler SJ, Strand M, Gelfand EW, Beebe DW. Experimentally manipulated sleep duration in adolescents with asthma: Feasibility and preliminary findings. Pediatr Pulmonol. 2015 Apr 14. [Epub ahead of print] PubMed PMID: 25872769
  • Vogelberg C, Moroni-Zentgraf P, Leonaviciute-Klimantaviciene M, Sigmund R, Hamelmann E, Engel M, Szefler S. A randomised dose-ranging study of tiotropium Respimat® in children with symptomatic asthma despite inhaled corticosteroids. Respir Res. 2015 Feb 7;16:20. PubMed PMID: 25851298
  • Teach SJ, Gergen PJ, Szefler SJ, Mitchell HE, Calatroni A, Wildfire J, Bloomberg GR, Kercsmar CM, Liu AH, Makhija MM, Matsui E, Morgan W, O'Connor G, Busse WW. Seasonal risk factors for asthma exacerbations among inner-city children. J Allergy Clin Immunol. 2015 Jun;135(6):1465-73.e5. PubMed PMID: 25794658
  • Gerald JK, Gerald LB, Vasquez MM, Morgan WJ, Boehmer SJ, Lemanske RF Jr, Mauger DT, Strunk RC, Szefler SJ, Zeiger RS, Bacharier LB, Bade E, Covar RA, Guilbert TW, Heidarian-Raissy H, Kelly HW, Malka-Rais J, Sorkness CA, Taussig LM, Chinchilli VM, Martinez FD. Markers of Differential Response to Inhaled Corticosteroid Treatment Among Children with Mild Persistent Asthma. J Allergy Clin Immunol Pract. 2015 Jul-Aug;3(4):540-6.e3. PubMed PMID: 25783161
  • Yang IV, Pedersen BS, Liu A, O'Connor GT, Teach SJ, Kattan M, Misiak RT, Gruchalla R, Steinbach SF, Szefler SJ, Gill MA, Calatroni A, David G, Hennessy CE, Davidson EJ, Zhang W, Gergen P, Togias A, Busse WW, Schwartz DA. DNA methylation and childhood asthma in the inner city. J Allergy Clin Immunol. 2015 Jul;136(1):69-80. PubMed PMID: 25769910
  • Pijnenburg MW, Baraldi E, Brand PL, Carlsen KH, Eber E, Frischer T, Hedlin G, Kulkarni N, Lex C, Mäkelä MJ, Mantzouranis E, Moeller A, Pavord I, Piacentini G, Price D, Rottier BL, Saglani S, Sly PD, Szefler SJ, Tonia T, Turner S, Wooler E, Lødrup Carlsen KC. Monitoring asthma in children. Eur Respir J. 2015 Apr;45(4):906-25. PubMed PMID: 25745042
  • Szefler SJ. Advances in pediatric asthma in 2014: Moving toward a population health perspective. J Allergy Clin Immunol. 2015 Mar;135(3):644-52. PubMed PMID: 25649079
  • Szefler SJ. Monitoring and adherence in asthma management. Lancet Respir Med. 2015 Mar;3(3):175-6. PubMed PMID: 25617214
  • Wang Y, Tong C, Wang Z, Wang Z, Mauger D, Tantisira KG, Israel E, Szefler SJ, Chinchilli VM, Boushey HA, Lazarus SC, Lemanske RF, Wu R. Pharmacodynamic genome-wide association study identifies new responsive loci for glucocorticoid intervention in asthma. Pharmacogenomics J. 2015 Oct;15(5):422-9. PubMed PMID: 25601762
  • Israel E, Lasky-Su J, Markezich A, Damask A, Szefler SJ, Schuemann B, Klanderman B, Sylvia J, Kazani S, Wu R, Martinez F, Boushey HA, Chinchilli VM, Mauger D, Weiss ST, Tantisira KG. Genome-wide association study of short-acting ß2-agonists. A novel genome-wide significant locus on chromosome 2 near ASB3. Am J Respir Crit Care Med. 2015 Mar 1;191(5):530-7. PubMed PMID: 25562107
  • Zemanick ET, Wagner BD, Robertson CE, Stevens MJ, Szefler SJ, Accurso FJ, Sagel SD, Harris JK. Assessment of Airway Microbiota and Inflammation in Cystic Fibrosis Using Multiple Sampling Methods. Ann Am Thorac Soc. 2014 Dec 4. [Epub ahead of print] PubMed PMID: 25474078
  • Pijnenburg MW, Szefler S. Personalized medicine in children with asthma. Paediatr Respir Rev. 2014 Nov 8. [Epub ahead of print] PubMed PMID: 25458797
  • Long A, Rothman K, Chen H, Carrigan G, Szefler S, EXCELS study authors. Reply. J Allergy Clin Immunol. 2014 Oct 29. [Epub ahead of print] PubMed PMID: 25441293
  • Dhami S, Nurmatov U, Agache I, Lau S, Muraro A, Jutel M, Roberts G, Akdis C, Bonini M, Calderon M, Casale T, Cavkaytar O, Cox L, Demoly P, Flood B, Hamelmann E, Izuhara K, Kalayci Ö, Kleine-Tebbe J, Nieto A, Papadopoulos N, Pfaar O, Rosenwasser L, Ryan D, Schmidt-Weber C, Szefler S, Wahn U, van Wijk RG, Wilkinson J, Sheikh A. Allergen immunotherapy for allergic asthma: protocol for a systematic review. Clin Transl Allergy. 2015;6:5. PubMed PMID: 26862389
  • Szefler SJ, Chmiel JF, Fitzpatrick AM, Giacoia G, Green TP, Jackson DJ, Nielsen HC, Phipatanakul W, Raissy HH. Asthma across the ages: Knowledge gaps in childhood asthma. J Allergy Clin Immunol. 2014 Jan;133(1):3-13. PubMed PMID: 24290281
  • Zemanick ET, Wagner BD, Robertson CE, Stevens MJ, Szefler SJ, Accurso FJ, Sagel SD, Harris JK. Assessment of Airway Microbiota and Inflammation in Cystic Fibrosis Using Multiple Sampling Methods. Ann Am Thorac Soc. 2014 Dec 4. [Epub ahead of print] PubMed PMID: 25474078
  • Pijnenburg MW, Szefler S. Personalized medicine in children with asthma. Paediatr Respir Rev. 2014 Nov 8. [Epub ahead of print] PubMed PMID: 25458797
  • Long A, Rothman K, Chen H, Carrigan G, Szefler S, EXCELS study authors. Reply. J Allergy Clin Immunol. 2014 Oct 29. [Epub ahead of print] PubMed PMID: 25441293
  • Meltzer LJ, Ullrich M, Szefler SJ. Sleep duration, sleep hygiene, and insomnia in adolescents with asthma. J Allergy Clin Immunol Pract. 2014 Sep-Oct;2(5):562-9. PubMed PMID: 25213049
  • Sharma S, Zhou X, Thibault DM, Himes BE, Liu A, Szefler SJ, Strunk R, Castro M, Hansel NN, Diette GB, Vonakis BM, Adkinson NF Jr, Avila L, Soto-Quiros M, Barraza-Villareal A, Lemanske RF Jr, Solway J, Krishnan J, White SR, Cheadle C, Berger AE, Fan J, Boorgula MP, Nicolae D, Gilliland F, Barnes K, London SJ, Martinez F, Ober C, Celedón JC, Carey VJ, Weiss ST, Raby BA. A genome-wide survey of CD4( ) lymphocyte regulatory genetic variants identifies novel asthma genes. J Allergy Clin Immunol. 2014 Nov;134(5):1153-62. PubMed PMID: 24934276
  • Malka J, Mauger DT, Covar R, Rabinovitch N, Lemanske RF Jr, Spahn JD, Strunk RC, Zeiger RS, Morgan WJ, Szefler SJ. Eczema and race as combined determinants for differential response to step-up asthma therapy. J Allergy Clin Immunol. 2014 Aug;134(2):483-5. PubMed PMID: 24835502
  • Szefler SJ, Chmiel JF, Fitzpatrick AM, Giacoia G, Green TP, Jackson DJ, Nielsen HC, Phipatanakul W, Raissy HH. Reply: To PMID 24290281. J Allergy Clin Immunol. 2014 Jun;133(6):1776-7. PubMed PMID: 24786239
  • Beigelman A, Zeiger RS, Mauger D, Strunk RC, Jackson DJ, Martinez FD, Morgan WJ, Covar R, Szefler SJ, Taussig LM, Bacharier LB, Childhood Asthma Research and Education (CARE) Network of the National Heart, Lung, and Blood Institute. The association between vitamin D status and the rate of exacerbations requiring oral corticosteroids in preschool children with recurrent wheezing. J Allergy Clin Immunol. 2014 May;133(5):1489-92, 1492.e1-3. PubMed PMID: 24698320
  • Cicutto L, Gleason M, Szefler SJ. Establishing school-centered asthma programs. J Allergy Clin Immunol. 2014 Dec;134(6):1223-1230. PubMed PMID: 25482867
  • Meltzer LJ, Ullrich M, Szefler SJ. Sleep duration, sleep hygiene, and insomnia in adolescents with asthma. J Allergy Clin Immunol Pract. 2014 Sep-Oct;2(5):562-9. PubMed PMID: 25213049
  • Sharma S, Zhou X, Thibault DM, Himes BE, Liu A, Szefler SJ, Strunk R, Castro M, Hansel NN, Diette GB, Vonakis BM, Adkinson NF Jr, Avila L, Soto-Quiros M, Barraza-Villareal A, Lemanske RF Jr, Solway J, Krishnan J, White SR, Cheadle C, Berger AE, Fan J, Boorgula MP, Nicolae D, Gilliland F, Barnes K, London SJ, Martinez F, Ober C, Celedón JC, Carey VJ, Weiss ST, Raby BA. A genome-wide survey of CD4( ) lymphocyte regulatory genetic variants identifies novel asthma genes. J Allergy Clin Immunol. 2014 Nov;134(5):1153-62. PubMed PMID: 24934276
  • Green AW, Goldstein S, Szefler SJ, Wanderer A, Weinberger M. In lasting tribute: Elliot F. Ellis, MD, 1929-2014. J Allergy Clin Immunol. 2014 May;133(5):1504-5. PubMed PMID: 24892145
  • Malka J, Mauger DT, Covar R, Rabinovitch N, Lemanske RF Jr, Spahn JD, Strunk RC, Zeiger RS, Morgan WJ, Szefler SJ. Eczema and race as combined determinants for differential response to step-up asthma therapy. J Allergy Clin Immunol. 2014 Aug;134(2):483-5. PubMed PMID: 24835502
  • Szefler SJ, Chmiel JF, Fitzpatrick AM, Giacoia G, Green TP, Jackson DJ, Nielsen HC, Phipatanakul W, Raissy HH. Reply: To PMID 24290281. J Allergy Clin Immunol. 2014 Jun;133(6):1776-7. PubMed PMID: 24786239
  • Beigelman A, Zeiger RS, Mauger D, Strunk RC, Jackson DJ, Martinez FD, Morgan WJ, Covar R, Szefler SJ, Taussig LM, Bacharier LB, Childhood Asthma Research and Education (CARE) Network of the National Heart, Lung, and Blood Institute. The association between vitamin D status and the rate of exacerbations requiring oral corticosteroids in preschool children with recurrent wheezing. J Allergy Clin Immunol. 2014 May;133(5):1489-92, 1492.e1-3. PubMed PMID: 24698320
  • Long A, Rahmaoui A, Rothman KJ, Guinan E, Eisner M, Bradley MS, Iribarren C, Chen H, Carrigan G, Rosén K, Szefler SJ. Incidence of malignancy in patients with moderate-to-severe asthma treated with or without omalizumab. J Allergy Clin Immunol. 2014 Sep;134(3):560-567.e4. PubMed PMID: 24679845
  • Szefler SJ. Advances in pediatric asthma in 2013: coordinating asthma care. J Allergy Clin Immunol. 2014 Mar;133(3):654-61. PubMed PMID: 24581430
  • Long A, Rahmaoui A, Rothman KJ, Guinan E, Eisner M, Bradley MS, Iribarren C, Chen H, Carrigan G, Rosén K, Szefler SJ. Incidence of malignancy in patients with moderate-to-severe asthma treated with or without omalizumab. J Allergy Clin Immunol. 2014 Sep;134(3):560-567.e4. PubMed PMID: 24679845
  • Park HW, Dahlin A, Tse S, Duan QL, Schuemann B, Martinez FD, Peters SP, Szefler SJ, Lima JJ, Kubo M, Tamari M, Tantisira KG. Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids. J Allergy Clin Immunol. 2014 Mar;133(3):664-9.e5. PubMed PMID: 24486069
  • Chang TS, Lemanske RF Jr, Mauger DT, Fitzpatrick AM, Sorkness CA, Szefler SJ, Gangnon RE, Page CD, Jackson DJ, on behalf of the Childhood Asthma Research and Education (CARE) Network Investigators. Childhood asthma clusters and response to therapy in clinical trials. J Allergy Clin Immunol. 2013 Oct 15. [Epub ahead of print] PubMed PMID: 24139497
  • Park HW, Dahlin A, Tse S, Duan QL, Schuemann B, Martinez FD, Peters SP, Szefler SJ, Lima JJ, Kubo M, Tamari M, Tantisira KG. Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids. J Allergy Clin Immunol. 2014 Mar;133(3):664-9.e5. PubMed PMID: 24486069
  • Szefler SJ, Chmiel JF, Fitzpatrick AM, Giacoia G, Green TP, Jackson DJ, Nielsen HC, Phipatanakul W, Raissy HH. Asthma across the ages: Knowledge gaps in childhood asthma. J Allergy Clin Immunol. 2014 Jan;133(1):3-13. PubMed PMID: 24290281
  • Chang TS, Lemanske RF Jr, Mauger DT, Fitzpatrick AM, Sorkness CA, Szefler SJ, Gangnon RE, Page CD, Jackson DJ, on behalf of the Childhood Asthma Research and Education (CARE) Network Investigators. Childhood asthma clusters and response to therapy in clinical trials. J Allergy Clin Immunol. 2013 Oct 15. [Epub ahead of print] PubMed PMID: 24139497
  • Rabinovitch N, Mauger DT, Reisdorph N, Covar R, Malka J, Lemanske RF Jr, Morgan WJ, Guilbert TW, Zeiger RS, Bacharier LB, Szefler SJ. Predictors of asthma control and lung function responsiveness to step 3 therapy in children with uncontrolled asthma. J Allergy Clin Immunol. 2013 Sep 28. [Epub ahead of print] PubMed PMID: 24084071
  • Szefler SJ, Carlsson LG, Uryniak T, Baker JW. Budesonide inhalation suspension versus montelukast in children aged 2 to 4 years with mild persistent asthma. J Allergy Clin Immunol Pract. 2013 Jan;1(1):58-64. PubMed PMID: 24229823
  • Chang TS, Lemanske RF Jr, Mauger DT, Fitzpatrick AM, Sorkness CA, Szefler SJ, Gangnon RE, Page CD, Jackson DJ, on behalf of the Childhood Asthma Research and Education (CARE) Network Investigators. Childhood asthma clusters and response to therapy in clinical trials. J Allergy Clin Immunol. 2013 Oct 15. [Epub ahead of print] PubMed PMID: 24139497
  • Peters SP, Bleecker ER, Kunselman SJ, Icitovic N, Moore WC, Pascual R, Ameredes BT, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Craig T, Denlinger LC, Engle LL, Dimango EA, Israel E, Kraft M, Lazarus SC, Lemanske RF Jr, Lugogo N, Martin RJ, Meyers DA, Ramsdell J, Sorkness CA, Sutherland ER, Wasserman SI, Walter MJ, Wechsler ME, Chinchilli VM, Szefler SJ, National Heart, Lung, and Blood Institute's Asthma Clinical Research Network. Predictors of response to tiotropium versus salmeterol in asthmatic adults. J Allergy Clin Immunol. 2013 Nov;132(5):1068-1074.e1. PubMed PMID: 24084072
  • Rabinovitch N, Mauger DT, Reisdorph N, Covar R, Malka J, Lemanske RF Jr, Morgan WJ, Guilbert TW, Zeiger RS, Bacharier LB, Szefler SJ. Predictors of asthma control and lung function responsiveness to step 3 therapy in children with uncontrolled asthma. J Allergy Clin Immunol. 2013 Sep 28. [Epub ahead of print] PubMed PMID: 24084071
  • Himes BE, Qiu W, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF Jr, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Nieuwenhuis MA, Postma DS, Vonk JM, Rafaels N, Hansel NN, Barnes K, Raby B, Tantisira KG, Weiss ST. ITGB5 and AGFG1 variants are associated with severity of airway responsiveness. BMC Med Genet. 2013 Aug 28;14:86. PubMed PMID: 23984888
  • Li X, Hawkins GA, Ampleford EJ, Moore WC, Li H, Hastie AT, Howard TD, Boushey HA, Busse WW, Calhoun WJ, Castro M, Erzurum SC, Israel E, Lemanske RF Jr, Szefler SJ, Wasserman SI, Wenzel SE, Peters SP, Meyers DA, Bleecker ER. Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients. J Allergy Clin Immunol. 2013 Aug;132(2):313-20.e15. PubMed PMID: 23541324
  • Himes BE, Sheppard K, Berndt A, Leme AS, Myers RA, Gignoux CR, Levin AM, Gauderman WJ, Yang JJ, Mathias RA, Romieu I, Torgerson DG, Roth LA, Huntsman S, Eng C, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF Jr, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Postma DS, Nieuwenhuis MA, Vonk JM, Lima JJ, Irvin CG, Peters SP, Kubo M, Tamari M, Nakamura Y, Litonjua AA, Tantisira KG, Raby BA, Bleecker ER, Meyers DA, London SJ, Barnes KC, Gilliland FD, Williams LK, Burchard EG, Nicolae DL, Ober C, DeMeo DL, Silverman EK, Paigen B, Churchill G, Shapiro SD, Weiss ST. Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene. PLoS One. 2013;8(2):e56179. PubMed PMID: 23457522
  • Raissy HH, Kelly HW, Harkins M, Szefler SJ. Inhaled corticosteroids in lung diseases. Am J Respir Crit Care Med. 2013 Apr 15;187(8):798-803. PubMed PMID: 23370915
  • Szefler SJ. Advances in pediatric asthma in 2012: moving toward asthma prevention. J Allergy Clin Immunol. 2013 Jan;131(1):36-46. PubMed PMID: 23199603
  • Denlinger LC, Manthei DM, Seibold MA, Ahn K, Bleecker E, Boushey HA, Calhoun WJ, Castro M, Chinchili VM, Fahy JV, Hawkins GA, Icitovic N, Israel E, Jarjour NN, King T, Kraft M, Lazarus SC, Lehman E, Martin RJ, Meyers DA, Peters SP, Sheerar D, Shi L, Sutherland ER, Szefler SJ, Wechsler ME, Sorkness CA, Lemanske RF Jr, NHLBI Asthma Clinical Research Network Investigators. P2X7-regulated protection from exacerbations and loss of control is independent of asthma maintenance therapy. Am J Respir Crit Care Med. 2013 Jan 1;187(1):28-33. PubMed PMID: 23144325
  • Tamesis GP, Covar RA, Strand M, Liu AH, Szefler SJ, Klinnert MD. Predictors for asthma at age 7 years for low-income children enrolled in the Childhood Asthma Prevention Study. J Pediatr. 2013 Mar;162(3):536-542.e2. PubMed PMID: 23036483
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Professional Memberships

  • American Academy of Allergy Asthma and Immunology , Member
  • American Academy of Pediatrics (AAP), Member
  • Society of Pediatric Research , Member
  • American Society of Pharmacology and Experimental Therapeutics , Member
  • Colorado Allergy Society , Member
  • American College of Allergy, Asthma and Immunology , Member
  • American Thoracic Society (ATS), Member
  • Colorado Trudeau Society/Medical Section of the American Lung Association of Colorado , Member

Practice Locations

Children's Hospital Colorado
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation
  • Children's Hospital Colorado

Specialty Information

Specialties
  • Pediatrics, Board Certification
  • Allergy and Immunology, Board Certification
Conditions & Treatments
  • Lungs and Breathing - Asthma
  • Immune System - Allergies
  • Immune System
  • Lungs and Breathing
Clinical Interest for Patients
I am interested in Childhood asthma; Asthma pharmacotherapy; Inhaled corticosteroids; Biomarkers; Predictors of treatment response and Monitoring treatment response; School-centered asthma programs.

General Information

Medical Schools:
  • MD, State University of New York - Buffalo (1975)
Undergraduate Schools:
  • BSc, State University of New York at Buffalo (NY) (1971)
Residency Programs:
  • University at Buffalo School of Medicine Program, Pediatrics (1977)
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Languages: English
Department: Pediatrics-Pulmonary Medicine
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