Kennon Heard, MD
Professor, Emergency Medicine-Medical Toxicology and Pharmacology

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Medical School:
  • MD, University of California, San Diego School of Medicine (1994)
Graduate School :
  • PhD, University of Colorado Health Sciences Center (2014)
Residency:
  • Denver Health Medical Center Program, Chief Resident, Emergency Medicine (1997)
Fellowships:
  • Denver Health Medical Center Program, Medical Toxicology (1999)
Languages: English
Department: Emergency Medicine-Medical Toxicology and Pharmacology

Professional Titles

  • Medical Toxicology Fellowship Director at the Rocky Mountain Poison and Drug Center
  • Section Chief of Medical Toxicology at the University of Colorado School of Medicine

Publications

  • Monte AA, Vest A, Reisz JA, Berninzoni D, Hart C, Dylla L, D'Alessandro A, Heard KJ, Wood C, Pattee J. Correction to: A Multi-Omic Mosaic Model of Acetaminophen Induced Alanine Aminotransferase Elevation. J Med Toxicol. 2023 Oct;19(4):416. PubMed PMID: 37365428
  • Monte AA, Vest A, Reisz JA, Berninzoni D, Hart C, Dylla L, D'Alessandro A, Heard KJ, Wood C, Pattee J. A Multi-Omic Mosaic Model of Acetaminophen Induced Alanine Aminotransferase Elevation. J Med Toxicol. 2023 Jul;19(3):255-261. PubMed PMID: 37231244
  • Simon M, Heard K. Are antimuscarinic effects common in hydroxyzine overdose? A cohort analysis of antimuscarinic effects in hydroxyzine and diphenhydramine-poisoned patients. Clin Toxicol (Phila). 2023 May;61(5):379-386. PubMed PMID: 37194685
  • Pepin L, Matsler N, Fontes A, Heard K, Flaherty BF, Monte AA. Fomepizole Therapy for Acetaminophen-Induced Liver Failure in an Infant. Pediatrics. 2023 Oct 1;152(4). PubMed PMID: 37681263
  • Hoppe JA, Ledbetter C, Tolle H, Heard K. Implementation of Electronic Health Record Integration and Clinical Decision Support to Improve Emergency Department Prescription Drug Monitoring Program Use. Ann Emerg Med. 2023 Aug 24. [Epub ahead of print] PubMed PMID: 37632496
  • Dart RC, Mullins ME, Matoushek T, Ruha AM, Burns MM, Simone K, Beuhler MC, Heard KJ, Mazer-Amirshahi M, Stork CM, Varney SM, Funk AR, Cantrell LF, Cole JB, Banner W, Stolbach AI, Hendrickson RG, Lucyk SN, Sivilotti MLA, Su MK, Nelson LS, Rumack BH. Management of Acetaminophen Poisoning in the US and Canada: A Consensus Statement. JAMA Netw Open. 2023 Aug 1;6(8):e2327739. PubMed PMID: 37552484
  • Simon M, Heard K. Response to Klein et al. 2023. Clin Toxicol (Phila). 2023 Jul;61(7):563-564. PubMed PMID: 37535033
  • Metz TD, McMillin GA, Silver RM, Allshouse AA, Heard K, Jensen TL, Wymore EM, Stickrath E, Conageski C, Kinney GL, Binswanger IA. Quantification of prenatal marijuana use: evaluation of the correlation between self-report, serum, urine and umbilical cord assays among women delivering at two urban Colorado hospitals. Addiction. 2022 Jan;117(1):172-181. PubMed PMID: 34142398
  • Monte AA, Arriaga Mackenzie I, Pattee J, Kaiser S, Willems E, Rumack B, Reynolds KM, Dart RC, Heard KJ. Genetic variants associated with ALT elevation from therapeutic acetaminophen. Clin Toxicol (Phila). 2022 Nov;60(11):1198-1204. PubMed PMID: 36102175
  • Arnold CG, Dylla L, Monte AA, Heard K, Heard S, D'Alessandro A, Reynolds K, Dart R, Rumack B, Sonn B. Metabolomic Evaluation of N-Acetyl-p-Benzoquinone Imine Protein Adduct Formation with Therapeutic Acetaminophen Administration: Sex-based Physiologic Differences. J Med Toxicol. 2022 Oct;18(4):297-310. PubMed PMID: 35751009
  • Comstock G, Kaiser S, Heard K, Wang GS. Significance of temperature in antimuscarinic toxicity: a case-control study. Clin Toxicol (Phila). 2022 Sep;60(9):1070-1072. PubMed PMID: 35735006
  • Metz TD, McMillin GA, Silver RM, Allshouse AA, Heard K, Jensen TL, Wymore EM, Stickrath E, Conageski C, Kinney GL, Binswanger IA. Quantification of prenatal marijuana use: evaluation of the correlation between self-report, serum, urine and umbilical cord assays among women delivering at two urban Colorado hospitals. Addiction. 2022 Jan;117(1):172-181. PubMed PMID: 34142398
  • Sonn BJ, Heard KJ, Heard SM, D'Alessandro A, Reynolds KM, Dart RC, Rumack BH, Monte AA. Metabolomic markers predictive of hepatic adaptation to therapeutic dosing of acetaminophen. Clin Toxicol (Phila). 2022 Feb;60(2):221-230. PubMed PMID: 34047639
  • Monte AA, Arriaga Mackenzie I, Pattee J, Kaiser S, Willems E, Rumack B, Reynolds KM, Dart RC, Heard KJ. Genetic variants associated with ALT elevation from therapeutic acetaminophen. Clin Toxicol (Phila). 2022 Nov;60(11):1198-1204. PubMed PMID: 36102175
  • Arnold CG, Dylla L, Monte AA, Heard K, Heard S, D'Alessandro A, Reynolds K, Dart R, Rumack B, Sonn B. Metabolomic Evaluation of N-Acetyl-p-Benzoquinone Imine Protein Adduct Formation with Therapeutic Acetaminophen Administration: Sex-based Physiologic Differences. J Med Toxicol. 2022 Oct;18(4):297-310. PubMed PMID: 35751009
  • Comstock G, Kaiser S, Heard K, Wang GS. Significance of temperature in antimuscarinic toxicity: a case-control study. Clin Toxicol (Phila). 2022 Sep;60(9):1070-1072. PubMed PMID: 35735006
  • Metz TD, McMillin GA, Silver RM, Allshouse AA, Heard K, Jensen TL, Wymore EM, Stickrath E, Conageski C, Kinney GL, Binswanger IA. Quantification of prenatal marijuana use: evaluation of the correlation between self-report, serum, urine and umbilical cord assays among women delivering at two urban Colorado hospitals. Addiction. 2022 Jan;117(1):172-181. PubMed PMID: 34142398
  • Sonn BJ, Heard KJ, Heard SM, D'Alessandro A, Reynolds KM, Dart RC, Rumack BH, Monte AA. Metabolomic markers predictive of hepatic adaptation to therapeutic dosing of acetaminophen. Clin Toxicol (Phila). 2022 Feb;60(2):221-230. PubMed PMID: 34047639
  • Clark RT, Johnson L, Billotti J, Foulds G, Ketels T, Heard K, Calvello Hynes E. Early Outcomes of Bivalirudin Therapy for Thrombotic Thrombocytopenia and Cerebral Venous Sinus Thrombosis After Ad26.COV2.S Vaccination. Ann Emerg Med. 2021 Oct;78(4):511-514. PubMed PMID: 34226070
  • Sonn BJ, Heard KJ, Heard SM, D'Alessandro A, Reynolds KM, Dart RC, Rumack BH, Monte AA. Metabolomic markers predictive of hepatic adaptation to therapeutic dosing of acetaminophen. Clin Toxicol (Phila). 2021 May 28;:1-10. [Epub ahead of print] PubMed PMID: 34047639
  • Pepin LC, Buchanan JA, Pizon AF, Heard K, Zuckerman M. Educating the Educators. J Med Toxicol. 2021 Apr;17(2):157-159. PubMed PMID: 33565003
  • Wang GS, Baker K, Ng P, Janis GC, Leonard J, Mistry RD, Heard K. A randomized trial comparing physostigmine vs lorazepam for treatment of antimuscarinic (anticholinergic) toxidrome. Clin Toxicol (Phila). 2021 Aug;59(8):698-704. PubMed PMID: 33295809
  • Monte AA, Sonn B, Saben J, Rumack BH, Reynolds KM, Dart RC, Heard KJ. The Genomics of Elevated ALT and Adducts in Therapeutic Acetaminophen Treatment: a Pilot Study. J Med Toxicol. 2021 Apr;17(2):160-167. PubMed PMID: 33051802
  • Zuckerman M, Kelly T, Heard K, Zosel A, Marlin M, Hoppe J. Physician attitudes on buprenorphine induction in the emergency department: results from a multistate survey. Clin Toxicol (Phila). 2021 Apr;59(4):279-285. PubMed PMID: 32870039
  • Clark RT, Johnson L, Billotti J, Foulds G, Ketels T, Heard K, Calvello Hynes E. Early Outcomes of Bivalirudin Therapy for Thrombotic Thrombocytopenia and Cerebral Venous Sinus Thrombosis After Ad26.COV2.S Vaccination. Ann Emerg Med. 2021 Oct;78(4):511-514. PubMed PMID: 34226070
  • Schimmel J, Heard K. Unknown Effect of Cannabis Use on Procedural Sedation Requirements. J Am Osteopath Assoc. 2020 Jan 1;120(1):4. PubMed PMID: 31904774
  • Wang GS, Bourne DWA, Klawitter J, Sempio C, Chapman K, Knupp K, Wempe MF, Borgelt L, Christians U, Heard K, Bajaj L. Disposition of oral delta-9 tetrahydrocannabinol (THC) in children receiving cannabis extracts for epilepsy. Clin Toxicol (Phila). 2020 Feb;58(2):124-128. PubMed PMID: 31111749
  • Wang GS, Baker K, Ng P, Janis GC, Leonard J, Mistry RD, Heard K. A randomized trial comparing physostigmine vs lorazepam for treatment of antimuscarinic (anticholinergic) toxidrome. Clin Toxicol (Phila). 2020 Dec 9;:1-13. [Epub ahead of print] PubMed PMID: 33295809
  • Monte AA, Sonn B, Saben J, Rumack BH, Reynolds KM, Dart RC, Heard KJ. The Genomics of Elevated ALT and Adducts in Therapeutic Acetaminophen Treatment: a Pilot Study. J Med Toxicol. 2020 Oct 13. [Epub ahead of print] PubMed PMID: 33051802
  • Zuckerman M, Kelly T, Heard K, Zosel A, Marlin M, Hoppe J. Physician attitudes on buprenorphine induction in the emergency department: results from a multistate survey. Clin Toxicol (Phila). 2020 Sep 1;:1-7. [Epub ahead of print] PubMed PMID: 32870039
  • Heard K, Ledbetter CM, Hoppe JA. Association of Emergency Department Opioid Administration With Ongoing Opioid Use: A Retrospective Cohort Study of Patients With Back Pain. Acad Emerg Med. 2020 Nov;27(11):1158-1165. PubMed PMID: 32609923
  • Wang GS, Bourne DWA, Klawitter J, Sempio C, Chapman K, Knupp K, Wempe MF, Borgelt L, Christians U, Leonard J, Heard K, Bajaj L. Disposition of Oral Cannabidiol-Rich Cannabis Extracts in Children with Epilepsy. Clin Pharmacokinet. 2020 Aug;59(8):1005-1012. PubMed PMID: 32048179
  • Kelly T, Hoppe JA, Zuckerman M, Khoshnoud A, Sholl B, Heard K. A novel social work approach to emergency department buprenorphine induction and warm hand-off to community providers. Am J Emerg Med. 2020 Jun;38(6):1286-1290. PubMed PMID: 31959523
  • Wong A, Heard K, Graudins A, Dart R, Sivilotti MLA. Adducts Post Acetaminophen Overdose Treated with a 12-Hour vs 20-Hour Acetylcysteine Infusion. J Med Toxicol. 2020 Apr;16(2):188-194. PubMed PMID: 31939054
  • Schimmel J, Heard K. Unknown Effect of Cannabis Use on Procedural Sedation Requirements. J Am Osteopath Assoc. 2020 Jan 1;120(1):4. PubMed PMID: 31904774
  • Heard K, Bebarta VS, Hoppe JA, Monte AA. Does administration of haloperidol or ketorolac decrease opioid administration for abdominal pain patients? A retrospective study. Am J Emerg Med. 2020 Mar;38(3):517-520. PubMed PMID: 31138518
  • Wang GS, Bourne DWA, Klawitter J, Sempio C, Chapman K, Knupp K, Wempe MF, Borgelt L, Christians U, Heard K, Bajaj L. Disposition of oral delta-9 tetrahydrocannabinol (THC) in children receiving cannabis extracts for epilepsy. Clin Toxicol (Phila). 2020 Feb;58(2):124-128. PubMed PMID: 31111749
  • Wang GS, Hoyte C, Roosevelt G, Heard K. The Continued Impact of Marijuana Legalization on Unintentional Pediatric Exposures in Colorado. Clin Pediatr (Phila). 2019 Jan;58(1):114-116. PubMed PMID: 30288992
  • Heard K, Monte AA, Wang GS. Another Perspective on Cannabis and Emergency Medicine in Colorado. West J Emerg Med. 2019 Oct 16;20(6):855-856. PubMed PMID: 31738711
  • Giles ED, Brown IL, MacLean PS, Pan Z, Melanson EL, Heard KJ, Cornier MA, Marden T, Higgins JA. The In Vivo Net Energy Content of Resistant Starch and Its Effect on Macronutrient Oxidation in Healthy Adults. Nutrients. 2019 Oct 16;11(10). PubMed PMID: 31623184
  • Wong A, Graudins A, Heard K, Dalhoff K, Sivilotti MLA. Improving the management of the paracetamol poisoned patient. EClinicalMedicine. 2019 Jul;12:10. PubMed PMID: 31388658
  • Heard K, Bebarta VS, Hoppe JA, Monte AA. Does administration of haloperidol or ketorolac decrease opioid administration for abdominal pain patients? A retrospective study. Am J Emerg Med. 2019 May 22. [Epub ahead of print] PubMed PMID: 31138518
  • Dart RC, Bush SP, Heard K, Arnold TC, Sutter M, Campagne D, Holstege CP, Seifert SA, Lo JCY, Quan D, Borron S, Meurer DA, Burnham RI, McNally J, Garcia-Ubbelohde W, Anderson VE. The Efficacy of Antivenin Latrodectus (Black Widow) Equine Immune F(ab')(2) Versus Placebo in the Treatment of Latrodectism: A Randomized, Double-Blind, Placebo-Controlled, Clinical Trial. Ann Emerg Med. 2019 Sep;74(3):439-449. PubMed PMID: 30926190
  • Heard K, Monte AA, Hoyte CO. Brief Commentary: Consequences of Marijuana-Observations From the Emergency Department. Ann Intern Med. 2019 Jan 15;170(2):124. PubMed PMID: 30615784
  • Metz TD, Silver RM, McMillin GA, Allshouse AA, Jensen TL, Mansfield C, Heard K, Kinney GL, Wymore E, Binswanger IA. Prenatal Marijuana Use by Self-Report and Umbilical Cord Sampling in a State With Marijuana Legalization. Obstet Gynecol. 2019 Jan;133(1):98-104. PubMed PMID: 30531577
  • Heard DG, Andresen KH, Guthmiller KM, Lucas R, Heard KJ, Blewer AL, Abella BS, Gent LM, Sasson C. Hands-Only Cardiopulmonary Resuscitation Education: A Comparison of On-Screen With Compression Feedback, Classroom, and Video Education. Ann Emerg Med. 2019 Jun;73(6):599-609. PubMed PMID: 30442510
  • Wang GS, Hoyte C, Roosevelt G, Heard K. The Continued Impact of Marijuana Legalization on Unintentional Pediatric Exposures in Colorado. Clin Pediatr (Phila). 2019 Jan;58(1):114-116. PubMed PMID: 30288992
  • Heard K, Monte AA, Wang GS. Another Perspective on Cannabis and Emergency Medicine in Colorado. West J Emerg Med. 2019 Oct 16;20(6):855-856. PubMed PMID: 31738711
  • Giles ED, Brown IL, MacLean PS, Pan Z, Melanson EL, Heard KJ, Cornier MA, Marden T, Higgins JA. The In Vivo Net Energy Content of Resistant Starch and Its Effect on Macronutrient Oxidation in Healthy Adults. Nutrients. 2019 Oct 16;11(10). PubMed PMID: 31623184
  • Wong A, Graudins A, Heard K, Dalhoff K, Sivilotti MLA. Improving the management of the paracetamol poisoned patient. EClinicalMedicine. 2019 Jul;12:10. PubMed PMID: 31388658
  • Dart RC, Bush SP, Heard K, Arnold TC, Sutter M, Campagne D, Holstege CP, Seifert SA, Lo JCY, Quan D, Borron S, Meurer DA, Burnham RI, McNally J, Garcia-Ubbelohde W, Anderson VE. The Efficacy of Antivenin Latrodectus (Black Widow) Equine Immune F(ab')(2) Versus Placebo in the Treatment of Latrodectism: A Randomized, Double-Blind, Placebo-Controlled, Clinical Trial. Ann Emerg Med. 2019 Sep;74(3):439-449. PubMed PMID: 30926190
  • Heard K, Monte AA, Hoyte CO. Brief Commentary: Consequences of Marijuana-Observations From the Emergency Department. Ann Intern Med. 2019 Jan 15;170(2):124. PubMed PMID: 30615784
  • Metz TD, Silver RM, McMillin GA, Allshouse AA, Jensen TL, Mansfield C, Heard K, Kinney GL, Wymore E, Binswanger IA. Prenatal Marijuana Use by Self-Report and Umbilical Cord Sampling in a State With Marijuana Legalization. Obstet Gynecol. 2019 Jan;133(1):98-104. PubMed PMID: 30531577
  • Wang GS, Hoyte C, Roosevelt G, Heard K. The Continued Impact of Marijuana Legalization on Unintentional Pediatric Exposures in Colorado. Clin Pediatr (Phila). 2019 Jan;58(1):114-116. PubMed PMID: 30288992
  • Heard DG, Andresen KH, Guthmiller KM, Lucas R, Heard KJ, Blewer AL, Abella BS, Gent LM, Sasson C. Hands-Only Cardiopulmonary Resuscitation Education: A Comparison of On-Screen With Compression Feedback, Classroom, and Video Education. Ann Emerg Med. 2019 Jun;73(6):599-609. PubMed PMID: 30442510
  • Metz TD, Silver RM, McMillin GA, Allshouse AA, Jensen TL, Mansfield C, Heard K, Kinney GL, Wymore E, Binswanger IA. Prenatal Marijuana Use by Self-Report and Umbilical Cord Sampling in a State With Marijuana Legalization. Obstet Gynecol. 2018 Dec 4. [Epub ahead of print] PubMed PMID: 30531577
  • Heard DG, Andresen KH, Guthmiller KM, Lucas R, Heard KJ, Blewer AL, Abella BS, Gent LM, Sasson C. Hands-Only Cardiopulmonary Resuscitation Education: A Comparison of On-Screen With Compression Feedback, Classroom, and Video Education. Ann Emerg Med. 2018 Nov 8. [Epub ahead of print] PubMed PMID: 30442510
  • Green JL, Anderson V, Dart RC, Heard K. Medication history assessment in research: A randomized controlled trial comparing tablet-based (eMedHAT) versus structured interview (MedHAT). Pharmacoepidemiol Drug Saf. 2018 Dec;27(12):1356-1360. PubMed PMID: 30289578
  • Buchanan J, Windels D, Druck J, Heard K. Assessment of toxicology knowledge in the fourth-year medical students: Three years of data. World J Emerg Med. 2018;9(3):191-194. PubMed PMID: 29796143
  • Heard K, Anderson VE, Lavonas EJ, Dart RC, Green JL. Serum paracetamol-protein adducts in ambulatory subjects: Relationship to recent reported paracetamol use. Biomarkers. 2018 May;23(3):288-292. PubMed PMID: 29179598
  • Wang GS, Hoppe J, Brou L, Heard K. In response to "Balancing the risks and benefits of medication organizers". Clin Toxicol (Phila). 2018 Feb;56(2):156. PubMed PMID: 28748717
  • Wang GS, Heard K, Roosevelt G. The Unintended Consequences of Marijuana Legalization. J Pediatr. 2017 Nov;190:12-13. PubMed PMID: 29144239
  • Heard K, Marlin MB, Nappe T, Hoyte CO. Common marijuana-related cases encountered in the emergency department. Am J Health Syst Pharm. 2017 Nov 15;74(22):1904-1908. PubMed PMID: 28947626
  • Wang GS, Hoppe J, Brou L, Heard K. In response to "Balancing the risks and benefits of medication organizers". Clin Toxicol (Phila). 2017 Jul 27;:1. [Epub ahead of print] PubMed PMID: 28748717
  • Wang GS, Hoppe JA, Brou L, Heard KJ. Medication organizers (pill minders) increase the risk for unintentional pediatric ingestions. Clin Toxicol (Phila). 2017 Sep;55(8):897-901. PubMed PMID: 28471310
  • Heard K, Anderson V, Dart RC, Kile D, Lavonas EJ, Green JL. Serum Acetaminophen Protein Adduct Concentrations in Pediatric Emergency Department Patients. J Pediatr Gastroenterol Nutr. 2017 Apr;64(4):533-535. PubMed PMID: 27846064
  • Maddry JK, Kester A, Heard K. Prolonged hypocalcemia refractory to calcium gluconate after ammonium bifluoride ingestion in a pediatric patient. Am J Emerg Med. 2017 Feb;35(2):378.e1-378.e2. PubMed PMID: 27609122
  • Siddiqui A, Belland L, Rivera-Reyes L, Handel D, Yadav K, Heard K, Eisenberg A, Khelemsky Y, Hwang U. A Multicenter Evaluation of Emergency Department Pain Care Across Different Types of Fractures. Pain Med. 2017 Jan 1;18(1):41-48. PubMed PMID: 27245631
  • Wang GS, Hoppe JA, Brou L, Heard KJ. Medication organizers (pill minders) increase the risk for unintentional pediatric ingestions. Clin Toxicol (Phila). 2017 Sep;55(8):897-901. PubMed PMID: 28471310
  • Heard K, Marlin MB, Nappe T, Hoyte CO. Common marijuana-related cases encountered in the emergency department. Am J Health Syst Pharm. 2017 Nov 15;74(22):1904-1908. PubMed PMID: 28947626
  • Heard K, Anderson V, Dart RC, Kile D, Lavonas EJ, Green JL. Serum Acetaminophen Protein Adduct Concentrations in Pediatric Emergency Department Patients. J Pediatr Gastroenterol Nutr. 2017 Apr;64(4):533-535. PubMed PMID: 27846064
  • Maddry JK, Kester A, Heard K. Prolonged hypocalcemia refractory to calcium gluconate after ammonium bifluoride ingestion in a pediatric patient. Am J Emerg Med. 2017 Feb;35(2):378.e1-378.e2. PubMed PMID: 27609122
  • Heard K, Anderson V, Dart RC, Kile D, Lavonas E, Green JL. Serum Acetaminophen Protein Adduct Concentrations in Pediatric Emergency Department Patients. J Pediatr Gastroenterol Nutr. 2016 Nov 14. [Epub ahead of print] PubMed PMID: 27846064
  • Maddry JK, Kester A, Heard K. Prolonged hypocalcemia refractory to calcium gluconate after ammonium bifluoride ingestion in a pediatric patient. Am J Emerg Med. 2016 Aug 18. [Epub ahead of print] PubMed PMID: 27609122
  • Kim HS, Heard KJ, Heard S, Hoppe JA. Opioid prescription fill rates after emergency department discharge. Am J Health Syst Pharm. 2016 Jun 15;73(12):902-7. PubMed PMID: 27261241
  • Siddiqui A, Belland L, Rivera-Reyes L, Handel D, Yadav K, Heard K, Eisenberg A, Khelemsky Y, Hwang U. A Multicenter Evaluation of Emergency Department Pain Care Across Different Types of Fractures. Pain Med. 2016 May 31. [Epub ahead of print] PubMed PMID: 27245631
  • Heard K, Anderson VE, Dart RC, Green JL. Accuracy of the Structured Medication History Assessment Tool (MedHAT) Compared with Recorded Real-Time Medication Use. Pharmacotherapy. 2016 May;36(5):496-504. PubMed PMID: 27029649
  • Yip L, Heard K. Potential adjunct treatment for high-risk acetaminophen overdose. Clin Toxicol (Phila). 2016 Jun;54(5):459. PubMed PMID: 26919296
  • Lucyk SN, Yarema MC, Sivilotti ML, Johnson DW, Nettel-Aguirre A, Victorino C, Bailey B, Dart RC, Heard K, Spyker DA, Rumack BH. Outcomes of Patients With Premature Discontinuation of the 21-h Intravenous N-Acetylcysteine Protocol After Acute Acetaminophen Overdose. J Emerg Med. 2016 Apr;50(4):629-37. PubMed PMID: 26899513
  • Seifert SA, Kovnat D, Anderson VE, Green JL, Dart RC, Heard KJ. Acute hepatotoxicity associated with therapeutic doses of intravenous acetaminophen. Clin Toxicol (Phila). 2016 Mar;54(3):282-5. PubMed PMID: 26763284
  • Heard K, Green JL, Anderson V, Bucher-Bartelson B, Dart RC. Paracetamol (acetaminophen) protein adduct concentrations during therapeutic dosing. Br J Clin Pharmacol. 2016 Mar;81(3):562-8. PubMed PMID: 26584404
  • Genco EK, Forster JE, Flaten H, Goss F, Heard KJ, Hoppe J, Monte AA. Clinically Inconsequential Alerts: The Characteristics of Opioid Drug Alerts and Their Utility in Preventing Adverse Drug Events in the Emergency Department. Ann Emerg Med. 2016 Feb;67(2):240-248.e3. PubMed PMID: 26553282
  • Zurlinden TJ, Heard K, Reisfeld B. A novel approach for estimating ingested dose associated with paracetamol overdose. Br J Clin Pharmacol. 2016 Apr;81(4):634-45. PubMed PMID: 26441245
  • Heard K, Green JL, Anderson V, Bucher-Bartelson B, Dart RC. Paracetamol (acetaminophen) protein adduct concentrations during therapeutic dosing. Br J Clin Pharmacol. 2015 Nov 19. [Epub ahead of print] PubMed PMID: 26584404
  • Miech R, Johnston L, O'Malley PM, Keyes KM, Heard K. Prescription Opioids in Adolescence and Future Opioid Misuse. Pediatrics. 2015 Nov;136(5):e1169-77. PubMed PMID: 26504126
  • Siddiqui A, Belland L, Rivera-Reyes L, Handel D, Yadav K, Heard K, Eisenberg A, Hwang U. A Multicenter Evaluation of the Impact of Sex on Abdominal and Fracture Pain Care. Med Care. 2015 Nov;53(11):948-53. PubMed PMID: 26465122
  • Zurlinden TJ, Heard K, Reisfeld B. A novel approach for estimating ingested dose associated with paracetamol overdose. Br J Clin Pharmacol. 2015 Oct 6. [Epub ahead of print] PubMed PMID: 26441245
  • Kim HS, Anderson JD, Saghafi O, Heard KJ, Monte AA. Cyclic vomiting presentations following marijuana liberalization in Colorado. Acad Emerg Med. 2015 Jun;22(6):694-9. PubMed PMID: 25903855
  • Frey SM, Wiegand TJ, Green JL, Heard KJ, Wilkins DG, Gorodetsky RM, Dart RC. Confirming the Causative Role of Acetaminophen in Indeterminate Acute Liver Failure Using Acetaminophen-Cysteine Adducts. J Med Toxicol. 2015 Jun;11(2):218-22. PubMed PMID: 25896948
  • Monte AA, Anderson P, Hoppe JA, Weinshilboum RM, Vasiliou V, Heard KJ. Accuracy of Electronic Medical Record Medication Reconciliation in Emergency Department Patients. J Emerg Med. 2015 Jul;49(1):78-84. PubMed PMID: 25797942
  • Wang GS, Monte A, Hatten B, Brent J, Buchanan J, Heard KJ. Initiation of a medical toxicology consult service at a tertiary care children's hospital. Clin Toxicol (Phila). 2015 May;53(4):192-4. PubMed PMID: 25686099
  • Cao D, Heard K, Foran M, Koyfman A. Intravenous lipid emulsion in the emergency department: a systematic review of recent literature. J Emerg Med. 2015 Mar;48(3):387-97. PubMed PMID: 25534900
  • Hoppe JA, Kim H, Heard K. Association of emergency department opioid initiation with recurrent opioid use. Ann Emerg Med. 2015 May;65(5):493-499.e4. PubMed PMID: 25534654
  • Monte AA, Zane RD, Heard KJ. The implications of marijuana legalization in Colorado. JAMA. 2015 Jan 20;313(3):241-2. PubMed PMID: 25486283
  • Monte AA, Heard KJ, Hoppe JA, Vasiliou V, Gonzalez FJ. The accuracy of self-reported drug ingestion histories in emergency department patients. J Clin Pharmacol. 2015 Jan;55(1):33-8. PubMed PMID: 25052325
  • Monte AA, Heard KJ, Hoppe JA, Vasiliou V, Gonzalez FJ. The accuracy of self-reported drug ingestion histories in emergency department patients. J Clin Pharmacol. 2015 Jan;55(1):33-8. PubMed PMID: 25052325
  • Wang GS, Roosevelt G, Le Lait MC, Martinez EM, Bucher-Bartelson B, Bronstein AC, Heard K. Association of Unintentional Pediatric Exposures With Decriminalization of Marijuana in the United States. Ann Emerg Med. 2014 Feb 3. [Epub ahead of print] PubMed PMID: 24507243
  • Monte AA, Bronstein AC, Cao DJ, Heard KJ, Hoppe JA, Hoyte CO, Iwanicki JL, Lavonas EJ. An outbreak of exposure to a novel synthetic cannabinoid. N Engl J Med. 2014 Jan 23;370(4):389-90. PubMed PMID: 24450915
  • Wang GS, Le Lait MC, Heard K. Unintentional pediatric exposures to central alpha-2 agonists reported to the National Poison Data System. J Pediatr. 2014 Jan;164(1):149-52. PubMed PMID: 24094880
  • Cao D, Heard K, Foran M, Koyfman A. Intravenous Lipid Emulsion in the Emergency Department: A Systematic Review of Recent Literature. J Emerg Med. 2014 Dec 19. [Epub ahead of print] PubMed PMID: 25534900
  • Hoppe JA, Kim H, Heard K. Association of Emergency Department Opioid Initiation With Recurrent Opioid Use. Ann Emerg Med. 2014 Dec 17. [Epub ahead of print] PubMed PMID: 25534654
  • Monte AA, Zane RD, Heard KJ. The Implications of Marijuana Legalization in Colorado. JAMA. 2014 Dec 8. [Epub ahead of print] PubMed PMID: 25486283
  • Hwang U, Belland LK, Handel DA, Yadav K, Heard K, Rivera-Reyes L, Eisenberg A, Noble MJ, Mekala S, Valley M, Winkel G, Todd KH, Morrison RS. Is all pain is treated equally? A multicenter evaluation of acute pain care by age. Pain. 2014 Dec;155(12):2568-74. PubMed PMID: 25244947
  • Monte AA, Heard KJ, Campbell J, Hamamura D, Weinshilboum RM, Vasiliou V. The effect of CYP2D6 drug-drug interactions on hydrocodone effectiveness. Acad Emerg Med. 2014 Aug;21(8):879-85. PubMed PMID: 25156930
  • Heard K, Green JL, Anderson V, Bucher-Bartelson B, Dart RC. A randomized, placebo-controlled trial to determine the course of aminotransferase elevation during prolonged acetaminophen administration. BMC Pharmacol Toxicol. 2014 Jul 22;15:39. PubMed PMID: 25047090
  • Maddry JK, Sessions D, Heard K, Lappan C, McManus J, Bebarta VS. Wartime toxicology: evaluation of a military medical toxicology telemedicine consults service to assist physicians serving overseas and in combat (2005-2012). J Med Toxicol. 2014 Sep;10(3):261-5. PubMed PMID: 24752493
  • Maddry JK, Varney SM, Sessions D, Heard K, Thaxton RE, Ganem VJ, Zarzabal LA, Bebarta VS. A comparison of simulation-based education versus lecture-based instruction for toxicology training in emergency medicine residents. J Med Toxicol. 2014 Dec;10(4):364-8. PubMed PMID: 24844460
  • Heard K, Rumack BH, Green JL, Bucher-Bartelson B, Heard S, Bronstein AC, Dart RC. A single-arm clinical trial of a 48-hour intravenous N-acetylcysteine protocol for treatment of acetaminophen poisoning. Clin Toxicol (Phila). 2014 Jun;52(5):512-8. PubMed PMID: 24708414
  • Smalley CM, Jacquet GA, Sande MK, Heard K, Druck J. Impact of a teaching service on emergency department throughput. West J Emerg Med. 2014 Mar;15(2):165-9. PubMed PMID: 24672605
  • Wang GS, Roosevelt G, Le Lait MC, Martinez EM, Bucher-Bartelson B, Bronstein AC, Heard K. Association of unintentional pediatric exposures with decriminalization of marijuana in the United States. Ann Emerg Med. 2014 Jun;63(6):684-9. PubMed PMID: 24507243
  • Monte AA, Bronstein AC, Cao DJ, Heard KJ, Hoppe JA, Hoyte CO, Iwanicki JL, Lavonas EJ. An outbreak of exposure to a novel synthetic cannabinoid. N Engl J Med. 2014 Jan 23;370(4):389-90. PubMed PMID: 24450915
  • Wang GS, Le Lait MC, Heard K. Unintentional pediatric exposures to central alpha-2 agonists reported to the National Poison Data System. J Pediatr. 2014 Jan;164(1):149-52. PubMed PMID: 24094880
  • Varney SM, Buchanan JA, Kokko J, Heard K. Acetylcysteine for acetaminophen overdose in patients who weigh >100 kg. Am J Ther. 2014 May-Jun;21(3):159-63. PubMed PMID: 23011167
  • Heard K, Bui A, Mlynarchek SL, Green JL, Bond GR, Clark RF, Kozer E, Koff RS, Dart RC. Toxicity from repeated doses of acetaminophen in children: assessment of causality and dose in reported cases. Am J Ther. 2014 May-Jun;21(3):174-83. PubMed PMID: 22407198
  • Sessions D, Heard K, Kosnett M. Fatal cesium chloride toxicity after alternative cancer treatment. J Altern Complement Med. 2013 Dec;19(12):973-5. PubMed PMID: 23841836
  • Wang GS, Roosevelt G, Heard K. Pediatric marijuana exposures in a medical marijuana state. JAMA Pediatr. 2013 Jul;167(7):630-3. PubMed PMID: 23712626
  • Hoppe JA, Houghland J, Yaron M, Heard K. Prescription history of emergency department patients prescribed opioids. West J Emerg Med. 2013 May;14(3):247-52. PubMed PMID: 23687544
  • Green JL, Heard KJ, Reynolds KM, Albert D. Oral and Intravenous Acetylcysteine for Treatment of Acetaminophen Toxicity: A Systematic Review and Meta-analysis. West J Emerg Med. 2013 May;14(3):218-26. PubMed PMID: 23687539
  • Wang GS, Deakyne S, Bajaj L, Yin S, Heard K, Roosevelt G. The limited utility of screening laboratory tests and electrocardiograms in the management of unintentional asymptomatic pediatric ingestions. J Emerg Med. 2013 Jul;45(1):34-8. PubMed PMID: 23561311
  • Dart RC, Bogdan G, Heard K, Bucher Bartelson B, Garcia-Ubbelohde W, Bush S, Arnold T, Clark RC, Hendey GW, Holstege C, Spradley EA. A randomized, double-blind, placebo-controlled trial of a highly purified equine F(ab)2 antibody black widow spider antivenom. Ann Emerg Med. 2013 Apr;61(4):458-67. PubMed PMID: 23380292
  • Hoyte CO, Albert D, Heard KJ. The use of energy drinks, dietary supplements, and prescription medications by United States college students to enhance athletic performance. J Community Health. 2013 Jun;38(3):575-80. PubMed PMID: 23371823
  • Wang GS, Banerji S, Roussil TK, Heard KJ. Survival after amphotericin B overdose treated with plasmapheresis. Ann Pharmacother. 2013 Feb;47(2):e9. PubMed PMID: 23362040
  • Miech R, Bohnert A, Heard K, Boardman J. Increasing use of nonmedical analgesics among younger cohorts in the United States: a birth cohort effect. J Adolesc Health. 2013 Jan;52(1):35-41. PubMed PMID: 23260832
  • Maddry JK, Amir MK, Sessions D, Heard K. Fatal dabigatran toxicity secondary to acute renal failure. Am J Emerg Med. 2013 Feb;31(2):462.e1-2. PubMed PMID: 23158612
  • Jacob J, Albert D, Heard K. Single-agent duloxetine ingestions. Hum Exp Toxicol. 2013 Apr;32(4):427-33. PubMed PMID: 23111877
  • Maddry JK, Breyer K, Cook KM, Heard K. Monomorphic ventricular tachycardia after intentional citalopram overdose. Am J Emerg Med. 2013 Feb;31(2):447.e5-8. PubMed PMID: 22867818
  • Buchanan JA, Eberhardt A, Tebb ZD, Heard K, Wendlandt RF, Kosnett MJ. Massive human ingestion of orpiment (arsenic trisulfide). J Emerg Med. 2013 Feb;44(2):367-72. PubMed PMID: 22541879
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Practice Locations

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Denver Health
777 Bannock St
Denver, CO 80204
303-436-6000

Hospital Affiliation
  • University of Colorado Hospital

Specialty Information

Specialties
  • Emergency Medicine, Board Certification (1997)
  • Medical Toxicology, Board Certification (2000, 2010)

General Information

Medical Schools:
  • MD, University of California, San Diego School of Medicine (1994)
Graduate Schools:
  • PhD, University of Colorado Health Sciences Center (2014)
Residency Programs:
  • Denver Health Medical Center Program, Chief Resident, Emergency Medicine (1997)
Fellowships:
  • Denver Health Medical Center Program, Medical Toxicology (1999)
Languages: English
Department: Emergency Medicine-Medical Toxicology and Pharmacology
SOM Resources
CU Resources
Contact Us
CU Anschutz
Fitzsimons Building
13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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