James Maloney, MD
Professor, Medicine-Pulmonary Sciences & Critical Care

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Medical School:
  • MD, Chicago Medical School at Rosalind Franklin University of Medicine & Science (1987)
Undergraduate School:
  • BS, University of Washington (WA) (1983)
Internship:
  • University of Colorado (University Hospital) Program (1998)
Residency:
  • University of Colorado (University Hospital) Program, Internal Medicine (1990)
Fellowships:
  • University of Colorado (University Hospital) Program, Pulmonary Disease and Critical Care Medicine (1996)
Languages: English
Department: Medicine-Pulmonary Sciences & Critical Care

Professional Titles

  • Medical Director, UCH Pulmonary Ward
  • Elected Member, UCH Medical Board

Research Interests

Pulmonary Hypertension High Altitude Medicine Pulmonary Embolism

Teaching

  • Block Director, CVPR (2017)
    School of Medicine, University of Colorado - Denver
    Oversee all teaching of cardiovascular, pulmonary, and renal physiology for MS1 students in a 6 week block in Spring

Publications

  • Rhoads, S., Maloney, J., Mantha, A. et al. Pneumocystis jirovecii Pneumonia in HIV-Negative, Non-transplant Patients: Epidemiology, Clinical Manifestations, Diagnosis, Treatment, and Prevention. Curr Fungal Infect Rep (2024). https://doi.org/10.1007/s12281-024-00482-8
  • Zagona-Prizio C, Pascoe MA, Corbisiero MF, Simon VC, Mann SE, Mayer KA, Maloney JP. Cadaveric emergency cricothyrotomy training for non-surgeons using a bronchoscopy-enhanced curriculum. PLoS One. 2023;18(3):e0282403. PubMed PMID: 36952528
  • Vargas Barahona L, Molina KC, Pedraza-Arévalo LC, Sillau S, Tagawa A, Scherger S, Chastain DB, Shapiro L, Tuells J, Franco-Paredes C, Hawkins KL, Maloney JP, Thompson GR 3rd, Henao-Martínez AF. Previous corticosteroid exposure associates with an increased Pneumocystis jirovecii pneumonia mortality among HIV-negative patients: a global research network with a follow-up multicenter case-control study. Ther Adv Infect Dis. 2023 Jan-Dec;10:20499361231159481. PubMed PMID: 36938147
  • Arguinchona LM, Zagona-Prizio C, Joyce ME, Chan ED, Maloney JP. Microvascular significance of TGF-ß axis activation in COVID-19. Front Cardiovasc Med. 2022;9:1054690. PubMed PMID: 36684608
  • Castleman MJ, Stumpf MM, Therrien NR, Smith MJ, Lesteberg KE, Palmer BE, Maloney JP, Janssen WJ, Mould KJ, Beckham JD, Pelanda R, Torres RM. Autoantibodies elicited with SARS-CoV-2 infection are linked to alterations in double negative B cells. Front Immunol. 2022;13:988125. PubMed PMID: 36131937
  • Castleman MJ, Stumpf MM, Therrien NR, Smith MJ, Lesteberg KE, Palmer BE, Maloney JP, Janssen WJ, Mould KJ, Beckham JD, Pelanda R, Torres RM. SARS-CoV-2 infection relaxes peripheral B cell tolerance. J Exp Med. 2022 Jun 6;219(6). PubMed PMID: 35420627
  • Bai X, Hippensteel J, Leavitt A, Maloney JP, Beckham D, Garcia C, Li Q, Freed BM, Ordway D, Sandhaus RA, Chan ED. Hypothesis: Alpha-1-antitrypsin is a promising treatment option for COVID-19. Med Hypotheses. 2021 Jan;146:110394. PubMed PMID: 33239231
  • Histopathological correlation of acute on chronic eosinophilic pneumonitis caused by vaporized cannabis oil inhalation
  • Lee MH, Cool CD, Maloney JP. Histopathological Correlation of Acute on Chronic Eosinophilic Pneumonitis Caused by Vaporized Cannabis Oil Inhalation. Chest. 2021 Mar;159(3):e137-e139. PubMed PMID: 33678280
  • Bai X, Hippensteel J, Leavitt A, Maloney JP, Beckham D, Garcia C, Li Q, Freed BM, Ordway D, Sandhaus RA, Chan ED. Hypothesis: Alpha-1-antitrypsin is a promising treatment option for COVID-19. Med Hypotheses. 2021 Jan;146:110394. PubMed PMID: 33239231
  • Kumar R, Mickael C, Kassa B, Sanders L, Hernandez-Saavedra D, Koyanagi DE, Kumar S, Pugliese SC, Thomas S, McClendon J, Maloney JP, Janssen WJ, Stenmark KR, Tuder RM, Graham BB. Interstitial macrophage-derived thrombospondin-1 contributes to hypoxia-induced pulmonary hypertension. Cardiovasc Res. 2020 Oct 1;116(12):2021-2030. PubMed PMID: 31710666
  • Kumar R, Mickael C, Kassa B, Sanders L, Hernandez-Saavedra D, Koyanagi DE, Kumar S, Pugliese SC, Thomas S, McClendon J, Maloney JP, Janssen WJ, Stenmark KR, Tuder RM, Graham BB. Interstitial Macrophage-Derived Thrombospondin-1 Contributes to Hypoxia-Induced Pulmonary Hypertension. Cardiovasc Res. 2019 Nov 9. [Epub ahead of print] PubMed PMID: 31710666
  • Maloney JP, Narasimhan J, Biller J. Decreased TGF-ß1 and VEGF Release in Cystic Fibrosis Platelets: Further Evidence for Platelet Defects in Cystic Fibrosis. Lung. 2016 Oct;194(5):791-8. PubMed PMID: 27423781
  • Maloney JP, Gao L. Proinflammatory Cytokines Increase Vascular Endothelial Growth Factor Expression in Alveolar Epithelial Cells. Mediators Inflamm. 2015;2015:387842. PubMed PMID: 26424968
View All (14 Total) View Less

Professional Memberships

  • American Thoracic Society, Member
  • American College of Chest Physicians, Fellow

Practice Locations

UCHealth Anschutz Inpatient Pavilion - Anschutz Medical Campus
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

Denver Veterans Affairs Medical Center
1055 Clermont St
Denver, CO 80220
1-888-336-8262

UCHealth Pulmonary Vascular Disease Clinic
(PH, PE/CTEPH, HHT, High Altitude) 
12505 E. 16th Ave, 3rd Floor, Inpatient Pavilion 2
Aurora, CO 80045
720-848-5300

Hospital Affiliation
  • University of Colorado Hospital

Specialty Information

Specialties
  • Pulmonary Disease and Critical Care Medicine, Board Certification (1994)
  • Pulmonary Disease, Board Certification (1991)
  • Critical Care Medicine, Board Certification (1995)
Conditions & Treatments
  • Critical Care
  • Lungs and Breathing - Lung Disease
  • Lungs and Breathing - Pulmonary Embolism
  • Lungs and Breathing
  • Lungs and Breathing - Chronic Thromboembolic Pulmonary Hypertension (CTEPH)

General Information

Medical Schools:
  • MD, Chicago Medical School at Rosalind Franklin University of Medicine & Science (1987)
Undergraduate Schools:
  • BS, University of Washington (WA) (1983)
Internships:
  • University of Colorado (University Hospital) Program (1998)
Residency Programs:
  • University of Colorado (University Hospital) Program, Internal Medicine (1990)
Fellowships:
  • University of Colorado (University Hospital) Program, Pulmonary Disease and Critical Care Medicine (1996)
Languages: English
Department: Medicine-Pulmonary Sciences & Critical Care
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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