Glenn Furuta, MD
Professor, Pediatrics-Gastroenterology, Hepatology and Nutrition

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Medical School:
  • MD, Baylor College of Medicine (1986)
Undergraduate School:
  • BA, University of Texas–Austin (TX) (1982)
Internship:
  • Baylor College of Medicine Program (1987)
Residency:
  • Baylor College of Medicine Program, Chief Resident, Pediatrics (1990)
Fellowships:
  • Children's Hospital/Harvard Medical School Program, Pediatric Gastroenterology (1993)
Languages: English, German
Department: Pediatrics-Gastroenterology, Hepatology and Nutrition

Professional Titles

  • Professor, Pediatrics-Gastroenterology, Hepatology and Nutrition
  • Director, Gastrointestinal Eosinophilic Diseases Program
  • La Cache Endowed Chair for GI Allergic and Immunologic Diseases

Recognition & Awards

  • Patient Family Experience Award, Healthgrades, (2017)
    >90% ratings from parents
  • Eosinophilic Gastrointestinal Diseases Service Award, Cincinnati Children's Hospital / Campaign Urging Research In Eosinophilic Disorders, (2017)
  • PRC 5 Star Excellence Award, PRC, (2011)

Publications

  • Inage E, Furuta GT, Menard-Katcher C, Masterson JC. Eosinophilic Esophagitis - Pathophysiology and its Clinical Implications. Am J Physiol Gastrointest Liver Physiol. 2018 Sep 13. [Epub ahead of print] PubMed PMID: 30212252
  • Chehade M, Jones SM, Pesek RD, Burks AW, Vickery BP, Wood RA, Leung DYM, Furuta GT, Fleischer DM, Henning AK, Dawson P, Lindblad RW, Sicherer SH, Abonia JP, Sherrill JD, Sampson HA, Rothenberg ME. Phenotypic Characterization of Eosinophilic Esophagitis in a Large Multicenter Patient Population from the Consortium for Food Allergy Research. J Allergy Clin Immunol Pract. 2018 Sep - Oct;6(5):1534-1544.e5. PubMed PMID: 30075341
  • Chehade M, Jones SM, Pesek RD, Burks AW, Vickery BP, Wood RA, Leung DYM, Furuta GT, Fleischer DM, Henning AK, Dawson P, Lindblad RW, Sicherer SH, Abonia JP, Sherrill JD, Sampson HA, Rothenberg ME. Phenotypic Characterization of Eosinophilic Esophagitis in a Large Multicenter Patient Population from the Consortium for Food Allergy Research. J Allergy Clin Immunol Pract. 2018 Sep - Oct;6(5):1534-1544.e5. PubMed PMID: 30075341
  • Ferreira CT, Vieira MC, Furuta GT, Barros FCLF, Chehade M. Eosinophilic esophagitis-Where are we today?. J Pediatr (Rio J). 2018 Aug 1. [Epub ahead of print] PubMed PMID: 30075121
  • Spergel JM, Dellon ES, Liacouras CA, Hirano I, Molina-Infante J, Bredenoord AJ, Furuta GT. Summary of the updated international consensus diagnostic criteria for eosinophilic esophagitis: AGREE conference. Ann Allergy Asthma Immunol. 2018 Sep;121(3):281-284. PubMed PMID: 30030146
  • Dellon ES, Liacouras CA, Molina-Infante J, Furuta GT, Spergel JM, Zevit N, Spechler SJ, Attwood SE, Straumann A, Aceves SS, Alexander JA, Atkins D, Arva NC, Blanchard C, Bonis PA, Book WM, Capocelli KE, Chehade M, Cheng E, Collins MH, Davis CM, Dias JA, Di Lorenzo C, Dohil R, Dupont C, Falk GW, Ferreira CT, Fox A, Gonsalves NP, Gupta SK, Katzka DA, Kinoshita Y, Menard-Katcher C, Kodroff E, Metz DC, Miehlke S, Muir AB, Mukkada VA, Murch S, Nurko S, Ohtsuka Y, Orel R, Papadopoulou A, Peterson KA, Philpott H, Putnam PE, Richter JE, Rosen R, Rothenberg ME, Schoepfer A, Scott MM, Shah N, Sheikh J, Souza RF, Strobel MJ, Talley NJ, Vaezi MF, Vandenplas Y, Vieira MC, Walker MM, Wechsler JB, Wershil BK, Wen T, Yang GY, Hirano I, Bredenoord AJ. Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference. Gastroenterology. 2018 Oct;155(4):1022-1033.e10. PubMed PMID: 30009819
  • Egan M, Furuta GT. Eosinophilic gastrointestinal diseases beyond eosinophilic esophagitis. Ann Allergy Asthma Immunol. 2018 Aug;121(2):162-167. PubMed PMID: 29940308
  • Ma C, van Rhijn BD, Jairath V, Nguyen TM, Parker CE, Aceves SS, Furuta GT, Gupta SK, Katzka DA, Safroneeva E, Schoepfer AM, Straumann A, Spergel JM, Pai RK, Feagan BG, Hirano I, Dellon ES, Bredenoord AJ. Heterogeneity in Clinical, Endoscopic, and Histologic Outcome Measures and Placebo Response Rates in Clinical Trials of Eosinophilic Esophagitis: A Systematic Review. Clin Gastroenterol Hepatol. 2018 Jun 14. [Epub ahead of print] PubMed PMID: 29908360
  • Kottyan LC, Maddox A, Braxton JR, Stucke EM, Mukkada V, Putnam PE, Abonia JP, Chehade M, Wood RA, Pesek RD, Vickery BP, Furuta GT, Dawson P, Sampson HA, Martin LJ, Kelly JA, Kimberly RP, Sivils K, Gaffney PM, Kaufman K, Harley JB, Rothenberg ME. Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis. Genes Immun. 2018 Jun 8. [Epub ahead of print] PubMed PMID: 29904099
  • Yadlapati R, Furuta GT, Wani S. The Ratio of SEP70 to Pepsin as a Biomarker of Laryngopharyngeal Reflux. Gastroenterology. 2018 Jul;155(1):224-226. PubMed PMID: 29883572
  • Aceves SS, King E, Collins MH, Yang GY, Capocelli KE, Abonia JP, Atkins D, Bonis PA, Carpenter CL, Dellon ES, Eby MD, Falk GW, Gonsalves N, Gupta SK, Hirano I, Kocher K, Krischer JP, Leung J, Lipscomb J, Menard-Katcher P, Mukkada VA, Pan Z, Spergel JM, Sun Q, Wershil BK, Rothenberg ME, Furuta GT. Alignment of parent- and child-reported outcomes and histology in eosinophilic esophagitis across multiple CEGIR sites. J Allergy Clin Immunol. 2018 Jul;142(1):130-138.e1. PubMed PMID: 29852258
  • Lee K, Furuta GT, Nguyen N. Eosinophilic Esophagitis Is an Underlying Cause for Gastrointestinal Concerns in Children. Front Pediatr. 2018;6:113. PubMed PMID: 29780792
  • Grozdanovic M, Laffey KG, Abdelkarim H, Hitchinson B, Harijith A, Moon HG, Park GY, Rousslang LK, Masterson JC, Furuta GT, Tarasova NI, Gaponenko V, Ackerman SJ. Novel peptide nanoparticle-biased antagonist of CCR3 blocks eosinophil recruitment and airway hyperresponsiveness. J Allergy Clin Immunol. 2018 May 17. [Epub ahead of print] PubMed PMID: 29778505
  • Shoda T, Wen T, Aceves SS, Abonia JP, Atkins D, Bonis PA, Caldwell JM, Capocelli KE, Carpenter CL, Collins MH, Dellon ES, Eby MD, Gonsalves N, Gupta SK, Falk GW, Hirano I, Menard-Katcher P, Kuhl JT, Krischer JP, Leung J, Mukkada VA, Spergel JM, Trimarchi MP, Yang GY, Zimmermann N, Furuta GT, Rothenberg ME. Eosinophilic oesophagitis endotype classification by molecular, clinical, and histopathological analyses: a cross-sectional study. Lancet Gastroenterol Hepatol. 2018 Jul;3(7):477-488. PubMed PMID: 29730081
  • Zevit N, Furuta GT. Eosinophilic Gastroenteritis and Colitis: Not Yet Ready for the Big Leagues. J Pediatr Gastroenterol Nutr. 2018 Jul;67(1):1-2. PubMed PMID: 29620603
  • Fahey LM, Chandramouleeswaran PM, Guan S, Benitez AJ, Furuta GT, Aceves SS, Wang ML, Liacouras CA, Muir AB, Sleiman PM, Hakonarson H, Spergel JM, Cianferoni A. Food allergen triggers are increased in children with the TSLP risk allele and eosinophilic esophagitis. Clin Transl Gastroenterol. 2018 Mar 6;9(3):139. PubMed PMID: 29511165
  • Warners MJ, Ambarus CA, Bredenoord AJ, Verheij J, Lauwers GY, Walsh JC, Katzka DA, Nelson S, van Viegen T, Furuta GT, Gupta SK, Stitt L, Zou G, Parker CE, Shackelton LM, D Haens GR, Sandborn WJ, Dellon ES, Feagan BG, Collins MH, Jairath V, Pai RK. Reliability of histologic assessment in patients with eosinophilic oesophagitis. Aliment Pharmacol Ther. 2018 Apr;47(7):940-950. PubMed PMID: 29460418
  • Wright BL, Nguyen N, Shim KP, Masterson JC, Jacobsen EA, Ochkur SI, Lee JJ, Furuta GT. Increased GATA-3 and T-bet expression in eosinophilic esophagitis versus gastroesophageal reflux disease. J Allergy Clin Immunol. 2018 May;141(5):1919-1921.e5. PubMed PMID: 29374572
  • Mark J, Fernando SD, Masterson JC, Pan Z, Capocelli KE, Furuta GT, de Zoeten EF. Clinical Implications of Pediatric Colonic Eosinophilia. J Pediatr Gastroenterol Nutr. 2017 Oct 31. [Epub ahead of print] PubMed PMID: 29095349
  • Mehta P, Furuta GT, Brennan T, Henry ML, Maune NC, Sundaram SS, Menard-Katcher C, Atkins D, Takurukura F, Giffen S, Pan Z, Haas AM. Nutritional State and Feeding Behaviors of Children With Eosinophilic Esophagitis and Gastroesophageal Reflux Disease. J Pediatr Gastroenterol Nutr. 2017 Sep 12. [Epub ahead of print] PubMed PMID: 28906318
  • Nguyen N, Fernando SD, Biette KA, Hammer JA, Capocelli KE, Kitzenberg DA, Glover LE, Colgan SP, Furuta GT, Masterson JC. TGF-ß1 alters esophageal epithelial barrier function by attenuation of claudin-7 in eosinophilic esophagitis. Mucosal Immunol. 2017 Aug 23. [Epub ahead of print] PubMed PMID: 28832026
  • O'Shea KM, Aceves SS, Dellon ES, Gupta SK, Spergel JM, Furuta GT, Rothenberg ME. Pathophysiology of Eosinophilic Esophagitis. Gastroenterology. 2017 Jul 27. [Epub ahead of print] PubMed PMID: 28757265
  • Hall CHT, Nguyen N, Furuta GT, Prager J, Deboer E, Deterding R, Menard-Katcher C, Capocelli KE, Kramer RE, Friedlander JA. Unsedated in Office Transgastrostomy Esophagoscopy (TGE) to Monitor Therapy in Pediatric Esophageal Disease. J Pediatr Gastroenterol Nutr. 2017 May 12. [Epub ahead of print] PubMed PMID: 28505050
  • Spergel JM, Dellon ES, Liacouras CA, Hirano I, Molina-Infante J, Bredenoord AJ, Furuta GT. Author's Response to Hopp's Commentary. Ann Allergy Asthma Immunol. 2018 Oct 13. [Epub ahead of print] PubMed PMID: 30326321
  • Neudecker V, Brodsky KS, Clambey ET, Schmidt EP, Packard TA, Davenport B, Standiford TJ, Weng T, Fletcher AA, Barthel L, Masterson JC, Furuta GT, Cai C, Blackburn MR, Ginde AA, Graner MW, Janssen WJ, Zemans RL, Evans CM, Burnham EL, Homann D, Moss M, Kreth S, Zacharowski K, Henson PM, Eltzschig HK. Neutrophil transfer of miR-223 to lung epithelial cells dampens acute lung injury in mice. Sci Transl Med. 2017 Sep 20;9(408). PubMed PMID: 28931657
  • Mehta P, Furuta GT, Brennan T, Henry ML, Maune NC, Sundaram SS, Menard-Katcher C, Atkins D, Takurukura F, Giffen S, Pan Z, Haas AM. Nutritional State and Feeding Behaviors of Children With Eosinophilic Esophagitis and Gastroesophageal Reflux Disease. J Pediatr Gastroenterol Nutr. 2017 Sep 12. [Epub ahead of print] PubMed PMID: 28906318
  • Nguyen N, Furuta GT, Friedlander JA. Videocapsule Endoscopy Identifies Small Bowel Lesions in Patients with Eosinophilic Enteritis. Clin Gastroenterol Hepatol. 2017 Sep 1. [Epub ahead of print] PubMed PMID: 28870663
  • Nguyen N, Fernando SD, Biette KA, Hammer JA, Capocelli KE, Kitzenberg DA, Glover LE, Colgan SP, Furuta GT, Masterson JC. TGF-ß1 alters esophageal epithelial barrier function by attenuation of claudin-7 in eosinophilic esophagitis. Mucosal Immunol. 2017 Aug 23. [Epub ahead of print] PubMed PMID: 28832026
  • O'Shea KM, Aceves SS, Dellon ES, Gupta SK, Spergel JM, Furuta GT, Rothenberg ME. Pathophysiology of Eosinophilic Esophagitis. Gastroenterology. 2017 Jul 27. [Epub ahead of print] PubMed PMID: 28757265
  • Rosenberg HF, Fryer AD, Munitz A, Bochner BS, Jacoby DB, Levi-Schaffer F, Gleich GJ, Furuta GT, Rothenberg ME, Lacy P, Fulkerson PC, Hogan SP, Ackerman SJ, Foster PS. In Memory and Celebration: Dr. James J. Lee. Clin Exp Allergy. 2017 Jul;47(7):980-981. PubMed PMID: 28547822
  • Menard-Katcher C, Benitez AJ, Pan Z, Ahmed FN, Wilkins BJ, Capocelli KE, Liacouras CA, Verma R, Spergel JM, Furuta GT, Muir AB. Influence of Age and Eosinophilic Esophagitis on Esophageal Distensibility in a Pediatric Cohort. Am J Gastroenterol. 2017 Sep;112(9):1466-1473. PubMed PMID: 28508868
  • Hall CHT, Nguyen N, Furuta GT, Prager J, Deboer E, Deterding R, Menard-Katcher C, Capocelli KE, Kramer RE, Friedlander JA. Unsedated in Office Transgastrostomy Esophagoscopy (TGE) to Monitor Therapy in Pediatric Esophageal Disease. J Pediatr Gastroenterol Nutr. 2017 May 12. [Epub ahead of print] PubMed PMID: 28505050
  • Neudecker V, Haneklaus M, Jensen O, Khailova L, Masterson JC, Tye H, Biette K, Jedlicka P, Brodsky KS, Gerich ME, Mack M, Robertson AAB, Cooper MA, Furuta GT, Dinarello CA, O'Neill LA, Eltzschig HK, Masters SL, McNamee EN. Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome. J Exp Med. 2017 Jun 5;214(6):1737-1752. PubMed PMID: 28487310
  • Togias A, Cooper SF, Acebal ML, Assa'ad A, Baker JR Jr, Beck LA, Block J, Byrd-Bredbenner C, Chan ES, Eichenfield LF, Fleischer DM, Fuchs GJ 3rd, Furuta GT, Greenhawt MJ, Gupta RS, Habich M, Jones SM, Keaton K, Muraro A, Plaut M, Rosenwasser LJ, Rotrosen D, Sampson HA, Schneider LC, Sicherer SH, Sidbury R, Spergel J, Stukus DR, Venter C, Boyce JA. Addendum Guidelines for the Prevention of Peanut Allergy in the United States: Summary of the National Institute of Allergy and Infectious Diseases-Sponsored Expert Panel. J Acad Nutr Diet. 2017 May;117(5):788-793. PubMed PMID: 28449793
  • Hirano I, Spechler S, Furuta G, Dellon ES. White Paper AGA: Drug Development for Eosinophilic Esophagitis. Clin Gastroenterol Hepatol. 2017 Aug;15(8):1173-1183. PubMed PMID: 28342955
  • Atkins D, Furuta GT, Liacouras CA, Spergel JM. Eosinophilic esophagitis phenotypes: Ready for prime time?. Pediatr Allergy Immunol. 2017 Jun;28(4):312-319. PubMed PMID: 28339136
  • Furuta GT, Aceves SS. The National Biome Initiative: An allergy perspective. J Allergy Clin Immunol. 2017 Apr;139(4):1131-1134. PubMed PMID: 28257973
  • Togias A, Cooper SF, Acebal ML, Assa'ad A, Baker JR Jr, Beck LA, Block J, Byrd-Bredbenner C, Chan ES, Eichenfield LF, Fleischer DM, Fuchs GJ 3rd, Furuta GT, Greenhawt MJ, Gupta RS, Habich M, Jones SM, Keaton K, Muraro A, Plaut M, Rosenwasser LJ, Rotrosen D, Sampson HA, Schneider LC, Sicherer SH, Sidbury R, Spergel J, Stukus DR, Venter C, Boyce JA. Addendum guidelines for the prevention of peanut allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases-sponsored expert panel. J Allergy Clin Immunol. 2017 Jan;139(1):29-44. PubMed PMID: 28065278
  • Menard-Katcher C, Furuta GT, Kramer RE. Dilation of Pediatric Eosinophilic Esophagitis - Adverse Events and Short Term Outcomes. J Pediatr Gastroenterol Nutr. 2016 Jul 18. [Epub ahead of print] PubMed PMID: 28055990
  • McNamee EN, Biette KA, Hammer J, Harris R, Miyazawa H, Lee JJ, Furuta GT, Masterson JC. Targeting GM-CSF in epithelial and vascular remodeling in experimental Eosinophilic Esophagitis. Allergy. 2016 Dec 7. [Epub ahead of print] PubMed PMID: 27926989
  • Case C, Furuta GT, Atkins D, Pan Z, Robinson J. Diet and Stress in Pediatric Eosinophilic Esophagitis. J Pediatr Gastroenterol Nutr. 2017 Sep;65(3):281-284. PubMed PMID: 27906799
  • Nguyen N, Furuta GT, Menard-Katcher C. Sticky Steroids-In Search Of An Approved Treatment For Eosinophilic Esophagitis. J Pediatr Gastroenterol Nutr. 2016 Jun 30. [Epub ahead of print] PubMed PMID: 27367789
  • Mehta P, Sundaram S, Furuta GT, Pan Z, Atkins D, Markowitz S. Propofol Use in Pediatric Patients With Food Allergy and Eosinophilic Esophagitis. J Pediatr Gastroenterol Nutr. 2016 Jun 8. [Epub ahead of print] PubMed PMID: 27276432
  • Whelan KA, Merves JF, Giroux V, Tanaka K, Guo A, Chandramouleeswaran PM, Benitez AJ, Dods K, Que J, Masterson JC, Fernando SD, Godwin BC, Klein-Szanto AJ, Chikwava K, Ruchelli ED, Hamilton KE, Muir AB, Wang ML, Furuta GT, Falk GW, Spergel JM, Nakagawa H. Autophagy mediates epithelial cytoprotection in eosinophilic oesophagitis. Gut. 2016 Feb 16. [Epub ahead of print] PubMed PMID: 26884425
  • Rosenberg HF, Masterson JC, Furuta GT. Eosinophils, probiotics, and the microbiome. J Leukoc Biol. 2016 Aug 22. [Epub ahead of print] PubMed PMID: 27549754
  • Nguyen N, Furuta GT, Masterson JC. Deeper Than the Epithelium: Role of Matrix and Fibroblasts in Pediatric and Adult Eosinophilic Esophagitis. J Pediatr Gastroenterol Nutr. 2016 Aug;63(2):168-9. PubMed PMID: 27457777
  • Frasch SC, McNamee EN, Kominsky D, Jedlicka P, Jakubzick C, Zemski Berry K, Mack M, Furuta GT, Lee JJ, Henson PM, Colgan SP, Bratton DL. G2A Signaling Dampens Colitic Inflammation via Production of IFN-?. J Immunol. 2016 Aug 15;197(4):1425-34. PubMed PMID: 27402702
  • Nguyen N, Furuta GT, Menard-Katcher C. Sticky Steroids-In Search Of An Approved Treatment For Eosinophilic Esophagitis. J Pediatr Gastroenterol Nutr. 2016 Jun 30. [Epub ahead of print] PubMed PMID: 27367789
  • Mehta P, Sundaram S, Furuta GT, Pan Z, Atkins D, Markowitz S. Propofol Use in Pediatric Patients With Food Allergy and Eosinophilic Esophagitis. J Pediatr Gastroenterol Nutr. 2016 Jun 8. [Epub ahead of print] PubMed PMID: 27276432
  • Dellon ES, Collins MH, Bonis PA, Leung J, Capocelli KE, Dohil R, Falk GW, Furuta GT, Menard-Katcher C, Gupta SK, Hirano I, Hiremath GS, Kagalwalla AF, Wershil BK, Liacouras CA, Muir AB, Mukkada VA, Putnam PE, Schoepfer AM, Straumann A, Wo JM, Yang GY, Rothenberg ME, Gonsalves N. Substantial Variability in Biopsy Practice Patterns Among Gastroenterologists for Suspected Eosinophilic Gastrointestinal Disorders. Clin Gastroenterol Hepatol. 2016 Apr 22. [Epub ahead of print] PubMed PMID: 27112108
  • Whelan KA, Merves JF, Giroux V, Tanaka K, Guo A, Chandramouleeswaran PM, Benitez AJ, Dods K, Que J, Masterson JC, Fernando SD, Godwin BC, Klein-Szanto AJ, Chikwava K, Ruchelli ED, Hamilton KE, Muir AB, Wang ML, Furuta GT, Falk GW, Spergel JM, Nakagawa H. Autophagy mediates epithelial cytoprotection in eosinophilic oesophagitis. Gut. 2016 Feb 16. [Epub ahead of print] PubMed PMID: 26884425
  • Merves JF, Whelan KA, Benitez AJ, Muir AB, Furuta GT, Wang ML, Falk GW, Spergel JM, Nakagawa H. ATG7 Gene Expression as a Novel Tissue Biomarker in Eosinophilic Esophagitis. Am J Gastroenterol. 2016 Jan;111(1):151-3. PubMed PMID: 26785669
  • Kliewer KL, Venter C, Cassin AM, Abonia JP, Aceves SS, Bonis PA, Dellon ES, Falk GW, Furuta GT, Gonsalves N, Gupta SK, Hirano I, Kagalwalla A, Leung J, Mukkada VA, Spergel JM, Rothenberg ME. Should wheat, barley, rye, and/or gluten be avoided in a 6-food elimination diet?. J Allergy Clin Immunol. 2016 Apr;137(4):1011-4. PubMed PMID: 26725190
  • Molina-Infante J, Bredenoord AJ, Cheng E, Dellon ES, Furuta GT, Gupta SK, Hirano I, Katzka DA, Moawad FJ, Rothenberg ME, Schoepfer A, Spechler SJ, Wen T, Straumann A, Lucendo AJ. Proton pump inhibitor-responsive oesophageal eosinophilia: an entity challenging current diagnostic criteria for eosinophilic oesophagitis. Gut. 2016 Mar;65(3):524-31. PubMed PMID: 26685124
  • Safroneeva E, Straumann A, Coslovsky M, Zwahlen M, Kuehni CE, Panczak R, Haas NA, Alexander JA, Dellon ES, Gonsalves N, Hirano I, Leung J, Bussmann C, Collins MH, Newbury RO, De Petris G, Smyrk TC, Woosley JT, Yan P, Yang GY, Romero Y, Katzka DA, Furuta GT, Gupta SK, Aceves SS, Chehade M, Spergel JM, Schoepfer AM. Symptoms Have Modest Accuracy in Detecting Endoscopic and Histologic Remission in Adults With Eosinophilic Esophagitis. Gastroenterology. 2016 Mar;150(3):581-590.e4. PubMed PMID: 26584601
  • Gonsalves N, Furuta GT, Atkins D. Eosinophilic Gastrointestinal Disorders Affect More Than Just the Esophagus. J Pediatr Gastroenterol Nutr. 2016 Jan;62(1):1-2. PubMed PMID: 26485607
  • Safroneeva E, Coslovsky M, Kuehni CE, Zwahlen M, Haas NA, Panczak R, Taft TH, Hirano I, Dellon ES, Gonsalves N, Leung J, Bussmann C, Woosley JT, Yan P, Romero Y, Furuta GT, Gupta SK, Aceves SS, Chehade M, Straumann A, Schoepfer AM. Eosinophilic oesophagitis: relationship of quality of life with clinical, endoscopic and histological activity. Aliment Pharmacol Ther. 2015 Oct;42(8):1000-10. PubMed PMID: 26271642
  • Masterson JC, Capocelli KE, Hosford L, Biette K, McNamee EN, de Zoeten EF, Harris R, Fernando SD, Jedlicka P, Protheroe C, Lee JJ, Furuta GT. Eosinophils and IL-33 Perpetuate Chronic Inflammation and Fibrosis in a Pediatric Population with Stricturing Crohn's Ileitis. Inflamm Bowel Dis. 2015 Oct;21(10):2429-40. PubMed PMID: 26218140
  • Mehta P, Furuta GT. Eosinophils in Gastrointestinal Disorders: Eosinophilic Gastrointestinal Diseases, Celiac Disease, Inflammatory Bowel Diseases, and Parasitic Infections. Immunol Allergy Clin North Am. 2015 Aug;35(3):413-37. PubMed PMID: 26209893
  • Menard-Katcher C, Swerdlow MP, Mehta P, Furuta GT, Fenton LZ. Contribution of Esophagram To The Evaluation of Complicated Pediatric Eosinophilic Esophagitis. J Pediatr Gastroenterol Nutr. 2015 May 20. [Epub ahead of print] PubMed PMID: 25988559
  • Aherne CM, Saeedi B, Collins CB, Masterson JC, McNamee EN, Perrenoud L, Rapp CR, Curtis VF, Bayless A, Fletcher A, Glover LE, Evans CM, Jedlicka P, Furuta GT, de Zoeten EF, Colgan SP, Eltzschig HK. Epithelial-specific A2B adenosine receptor signaling protects the colonic epithelial barrier during acute colitis. Mucosal Immunol. 2015 May;8(3):699. PubMed PMID: 25943416
  • Saeedi BJ, Kao DJ, Kitzenberg DA, Dobrinskikh E, Schwisow KD, Masterson JC, Kendrick AA, Kelly CJ, Bayless AJ, Kominsky DJ, Campbell EL, Kuhn KA, Furuta GT, Colgan SP, Glover LE. HIF-dependent regulation of claudin-1 is central to intestinal epithelial tight junction integrity. Mol Biol Cell. 2015 Jun 15;26(12):2252-62. PubMed PMID: 25904334
  • Schoepfer AM, Panczak R, Zwahlen M, Kuehni CE, Coslovsky M, Maurer E, Haas NA, Alexander JA, Dellon ES, Gonsalves N, Hirano I, Leung J, Bussmann C, Collins MH, Newbury RO, De Petris G, Smyrk TC, Woosley JT, Yan P, Yang GY, Romero Y, Katzka DA, Furuta GT, Gupta SK, Aceves SS, Chehade M, Blanchard C, Straumann A, Safroneeva E. How do gastroenterologists assess overall activity of eosinophilic esophagitis in adult patients?. Am J Gastroenterol. 2015 Mar;110(3):402-14. PubMed PMID: 25732414
  • Menard-Katcher C, Furuta GT, Masterson JC. Mucosal Inflammation, Esophageal Eosinophilia and Celiac Disease, A little "pinch" will have to do you. J Pediatr Gastroenterol Nutr. 2015 Jan 21. [Epub ahead of print] PubMed PMID: 25611031
  • Chehade M, Aceves SS, Furuta GT, Fleischer DM. Food allergy and eosinophilic esophagitis: what do we do?. J Allergy Clin Immunol Pract. 2015 Jan-Feb;3(1):25-32. PubMed PMID: 25577614
  • Wen T, Dellon ES, Moawad FJ, Furuta GT, Aceves SS, Rothenberg ME. Transcriptome analysis of proton pump inhibitor-responsive esophageal eosinophilia reveals proton pump inhibitor-reversible allergic inflammation. J Allergy Clin Immunol. 2014 Oct 19. [Epub ahead of print] PubMed PMID: 25441638
  • Capocelli KE, Fernando SD, Menard-Katcher C, Furuta GT, Masterson JC, Wartchow EP. Ultrastructural features of eosinophilic oesophagitis: impact of treatment on desmosomes. J Clin Pathol. 2015 Jan;68(1):51-6. PubMed PMID: 25359789
  • Aherne CM, Saeedi B, Collins CB, Masterson JC, McNamee EN, Perrenoud L, Rapp CR, Curtis VF, Bayless A, Fletcher A, Glover LE, Evans CM, Jedlicka P, Furuta GT, de Zoeten EF, Colgan SP, Eltzschig HK. Epithelial-specific A2B adenosine receptor signaling protects the colonic epithelial barrier during acute colitis. Mucosal Immunol. 2015 Apr 8. [Epub ahead of print] PubMed PMID: 25850656
  • Friedlander JA, DeBoer EM, Soden JS, Furuta GT, Menard-Katcher CD, Atkins D, Fleischer DM, Kramer RE, Deterding RR, Capocelli KE, Prager JD. Unsedated transnasal esophagoscopy for monitoring therapy in pediatric eosinophilic esophagitis. Gastrointest Endosc. 2015 Jul 2. [Epub ahead of print] PubMed PMID: 26142551
  • Nguyen N, Furuta GT, Menard-Katcher C. Recognition and Assessment of Eosinophilic Esophagitis: The Development of New Clinical Outcome Metrics. Gastroenterol Hepatol (N Y). 2015 Oct;11(10):670-4. PubMed PMID: 27330494
  • Harris JK, Fang R, Wagner BD, Choe HN, Kelly CJ, Schroeder S, Moore W, Stevens MJ, Yeckes A, Amsden K, Kagalwalla AF, Zalewski A, Hirano I, Gonsalves N, Henry LN, Masterson JC, Robertson CE, Leung DY, Pace NR, Ackerman SJ, Furuta GT, Fillon SA. Esophageal microbiome in eosinophilic esophagitis. PLoS One. 2015;10(5):e0128346. PubMed PMID: 26020633
  • Wen T, Dellon ES, Moawad FJ, Furuta GT, Aceves SS, Rothenberg ME. Transcriptome analysis of proton pump inhibitor-responsive esophageal eosinophilia reveals proton pump inhibitor-reversible allergic inflammation. J Allergy Clin Immunol. 2014 Oct 19. [Epub ahead of print] PubMed PMID: 25441638
  • Sleiman PM, Wang ML, Cianferoni A, Aceves S, Gonsalves N, Nadeau K, Bredenoord AJ, Furuta GT, Spergel JM, Hakonarson H. GWAS identifies four novel eosinophilic esophagitis loci. Nat Commun. 2014 Nov 19;5:5593. PubMed PMID: 25407941
  • Alexander ES, Martin LJ, Collins MH, Kottyan LC, Sucharew H, He H, Mukkada VA, Succop PA, Abonia JP, Foote H, Eby MD, Grotjan TM, Greenler AJ, Dellon ES, Demain JG, Furuta GT, Gurian LE, Harley JB, Hopp RJ, Kagalwalla A, Kaul A, Nadeau KC, Noel RJ, Putnam PE, von Tiehl KF, Rothenberg ME. Twin and family studies reveal strong environmental and weaker genetic cues explaining heritability of eosinophilic esophagitis. J Allergy Clin Immunol. 2014 Nov;134(5):1084-1092.e1. PubMed PMID: 25258143
  • Masterson JC, McNamee EN, Fillon SA, Hosford L, Harris R, Fernando SD, Jedlicka P, Iwamoto R, Jacobsen E, Protheroe C, Eltzschig HK, Colgan SP, Arita M, Lee JJ, Furuta GT. Eosinophil-mediated signalling attenuates inflammatory responses in experimental colitis. Gut. 2014 Sep 10. [Epub ahead of print] PubMed PMID: 25209655
  • Schoepfer AM, Straumann A, Panczak R, Coslovsky M, Kuehni CE, Maurer E, Haas NA, Romero Y, Hirano I, Alexander JA, Gonsalves N, Furuta GT, Dellon ES, Leung J, Collins MH, Bussmann C, Netzer P, Gupta SK, Aceves SS, Chehade M, Moawad FJ, Enders FT, Yost KJ, Taft TH, Kern E, Zwahlen M, Safroneeva E, International Eosinophilic Esophagitis Activity Index Study Group. Development and validation of a symptom-based activity index for adults with eosinophilic esophagitis. Gastroenterology. 2014 Dec;147(6):1255-1266.e21. PubMed PMID: 25160980
  • Klinnert MD, Silveira L, Harris R, Moore W, Atkins D, Fleischer DM, Menard-Katcher C, Aceves S, Spergel JM, Franciosi JP, Furuta GT. Health-related quality of life over time in children with eosinophilic esophagitis and their families. J Pediatr Gastroenterol Nutr. 2014 Sep;59(3):308-16. PubMed PMID: 24897164
  • Attwood SE, Furuta GT. Eosinophilic esophagitis: historical perspective on an evolving disease. Gastroenterol Clin North Am. 2014 Jun;43(2):185-99. PubMed PMID: 24813509
  • Furuta GT, Atkins FD, Lee NA, Lee JJ. Changing roles of eosinophils in health and disease. Ann Allergy Asthma Immunol. 2014 Jul;113(1):3-8. PubMed PMID: 24795292
  • Butz BK, Wen T, Gleich GJ, Furuta GT, Spergel J, King E, Kramer RE, Collins MH, Stucke E, Mangeot C, Jackson WD, O'Gorman M, Abonia JP, Pentiuk S, Putnam PE, Rothenberg ME. Efficacy, dose reduction, and resistance to high-dose fluticasone in patients with eosinophilic esophagitis. Gastroenterology. 2014 Aug;147(2):324-33.e5. PubMed PMID: 24768678
  • Neu M, Schmiege SJ, Pan Z, Fehringer K, Workman R, Marcheggianni-Howard C, Furuta GT. Interactions during feeding with mothers and their infants with symptoms of gastroesophageal reflux. J Altern Complement Med. 2014 Jun;20(6):493-9. PubMed PMID: 24742255
  • Mukkada VA, Furuta GT. Management of refractory eosinophilic esophagitis. Dig Dis. 2014;32(1-2):134-8. PubMed PMID: 24603397
  • Menard-Katcher C, Furuta GT. Non- and semi-invasive methods of monitoring eosinophilic esophagitis. Dig Dis. 2014;32(1-2):102-6. PubMed PMID: 24603390
  • Neu M, Pan Z, Workman R, Marcheggiani-Howard C, Furuta G, Laudenslager ML. Benefits of Massage Therapy for Infants With Symptoms of Gastroesophageal Reflux Disease. Biol Res Nurs. 2013 Dec 30. [Epub ahead of print] PubMed PMID: 24379449
  • Masterson JC, McNamee EN, Hosford L, Capocelli KE, Ruybal J, Fillon SA, Doyle AD, Eltzschig HK, Rustgi AK, Protheroe CA, Lee NA, Lee JJ, Furuta GT. Local hypersensitivity reaction in transgenic mice with squamous epithelial IL-5 overexpression provides a novel model of eosinophilic oesophagitis. Gut. 2012 Nov 17. [Epub ahead of print] PubMed PMID: 23161496
  • Schoepfer AM, Straumann A, Panczak R, Coslovsky M, Kuehni CE, Maurer E, Haas NA, Romero Y, Hirano I, Alexander JA, Gonsalves N, Furuta GT, Dellon ES, Leung J, Collins MH, Bussmann C, Netzer P, Gupta SK, Aceves SS, Chehade M, Moawad FJ, Enders FT, Yost KJ, Taft TH, Kern E, Zwahlen M, Safroneeva E, International Eosinophilic Esophagitis Activity Index Study Group. Development and validation of a symptom-based activity index for adults with eosinophilic esophagitis. Gastroenterology. 2014 Dec;147(6):1255-1266.e21. PubMed PMID: 25160980
  • Neu M, Pan Z, Workman R, Marcheggiani-Howard C, Furuta G, Laudenslager ML. Benefits of Massage Therapy for Infants With Symptoms of Gastroesophageal Reflux Disease. Biol Res Nurs. 2013 Dec 30. [Epub ahead of print] PubMed PMID: 24379449
  • Furuta GT, Atkins D, Capocelli KE, de Zoeten EF, Fleischer D, Menard-Katcher C. Antitumor necrosis factor, infliximab, and adalimumab: use with caution in eosinophilic bowel disease. J Pediatr Gastroenterol Nutr. 2013 Oct;57(4):e25. PubMed PMID: 23820407
  • Harris RF, Menard-Katcher C, Atkins D, Furuta GT, Klinnert MD. Psychosocial dysfunction in children and adolescents with eosinophilic esophagitis. J Pediatr Gastroenterol Nutr. 2013 Oct;57(4):500-5. PubMed PMID: 23752077
  • Dellon ES, Gonsalves N, Hirano I, Furuta GT, Liacouras CA, Katzka DA, American College of Gastroenterology. ACG clinical guideline: Evidenced based approach to the diagnosis and management of esophageal eosinophilia and eosinophilic esophagitis (EoE). Am J Gastroenterol. 2013 May;108(5):679-92; quiz 693. PubMed PMID: 23567357
  • Franciosi JP, Hommel KA, Bendo CB, King EC, Collins MH, Eby MD, Marsolo K, Abonia JP, von Tiehl KF, Putnam PE, Greenler AJ, Greenberg AB, Bryson RA, Davis CM, Olive AP, Gupta SK, Erwin EA, Klinnert MD, Spergel JM, Denham JM, Furuta GT, Rothenberg ME, Varni JW. PedsQL eosinophilic esophagitis module: feasibility, reliability, and validity. J Pediatr Gastroenterol Nutr. 2013 Jul;57(1):57-66. PubMed PMID: 23478422
  • Schroeder S, Robinson ZD, Masterson JC, Hosford L, Moore W, Pan Z, Harris R, Souza RF, Spechler SJ, Fillon SA, Furuta GT. Esophageal human ß-defensin expression in eosinophilic esophagitis. Pediatr Res. 2013 May;73(5):647-54. PubMed PMID: 23385963
  • Brandon JL, Schroeder S, Furuta GT, Capocelli K, Masterson JC, Fenton LZ. CT imaging features of eosinophilic colitis in children. Pediatr Radiol. 2013 Jun;43(6):697-702. PubMed PMID: 23361493
  • Schroeder S, Capocelli KE, Masterson JC, Harris R, Protheroe C, Lee JJ, Furuta GT. Effect of proton pump inhibitor on esophageal eosinophilia. J Pediatr Gastroenterol Nutr. 2013 Feb;56(2):166-72. PubMed PMID: 23325438
  • Ngo PD, Macleod RJ, Mukkada V, Turki R, Furuta GT. Epithelial calcium-sensing receptor activation by eosinophil granule protein analog stimulates collagen matrix contraction. Pediatr Res. 2012 Dec 26. [Epub ahead of print] PubMed PMID: 23269116
  • Furuta GT, Kagalwalla AF, Lee JJ, Alumkal P, Maybruck BT, Fillon S, Masterson JC, Ochkur S, Protheroe C, Moore W, Pan Z, Amsden K, Robinson Z, Capocelli K, Mukkada V, Atkins D, Fleischer D, Hosford L, Kwatia MA, Schroeder S, Kelly C, Lovell M, Melin-Aldana H, Ackerman SJ. The oesophageal string test: a novel, minimally invasive method measures mucosal inflammation in eosinophilic oesophagitis. Gut. 2012 Aug 15. [Epub ahead of print] PubMed PMID: 22895393
  • Ngo PD, Macleod RJ, Mukkada V, Turki R, Furuta GT. Epithelial calcium-sensing receptor activation by eosinophil granule protein analog stimulates collagen matrix contraction. Pediatr Res. 2012 Dec 26. [Epub ahead of print] PubMed PMID: 23269116
  • Masterson JC, McNamee EN, Hosford L, Capocelli KE, Ruybal J, Fillon SA, Doyle AD, Eltzschig HK, Rustgi AK, Protheroe CA, Lee NA, Lee JJ, Furuta GT. Local hypersensitivity reaction in transgenic mice with squamous epithelial IL-5 overexpression provides a novel model of eosinophilic oesophagitis. Gut. 2012 Nov 17. [Epub ahead of print] PubMed PMID: 23161496
  • Furuta GT, Williams K, Kooros K, Kaul A, Panzer R, Coury DL, Fuchs G. Management of constipation in children and adolescents with autism spectrum disorders. Pediatrics. 2012 Nov;130 Suppl 2:S98-105. PubMed PMID: 23118260
  • Fillon SA, Harris JK, Wagner BD, Kelly CJ, Stevens MJ, Moore W, Fang R, Schroeder S, Masterson JC, Robertson CE, Pace NR, Ackerman SJ, Furuta GT. Novel device to sample the esophageal microbiome--the esophageal string test. PLoS One. 2012;7(9):e42938. PubMed PMID: 22957025
  • Rothenberg ME, Aceves S, Bonis PA, Collins MH, Gonsalves N, Gupta SK, Hirano I, Liacouras CA, Putnam PE, Spergel JM, Straumann A, Wershil BK, Furuta GT. Working with the US Food and Drug Administration: progress and timelines in understanding and treating patients with eosinophilic esophagitis. J Allergy Clin Immunol. 2012 Sep;130(3):617-9. PubMed PMID: 22935588
  • Bochner BS, Book W, Busse WW, Butterfield J, Furuta GT, Gleich GJ, Klion AD, Lee JJ, Leiferman KM, Minnicozzi M, Moqbel R, Rothenberg ME, Schwartz LB, Simon HU, Wechsler ME, Weller PF. Workshop report from the National Institutes of Health Taskforce on the Research Needs of Eosinophil-Associated Diseases (TREAD). J Allergy Clin Immunol. 2012 Sep;130(3):587-96. PubMed PMID: 22935587
  • Furuta GT, Kagalwalla AF, Lee JJ, Alumkal P, Maybruck BT, Fillon S, Masterson JC, Ochkur S, Protheroe C, Moore W, Pan Z, Amsden K, Robinson Z, Capocelli K, Mukkada V, Atkins D, Fleischer D, Hosford L, Kwatia MA, Schroeder S, Kelly C, Lovell M, Melin-Aldana H, Ackerman SJ. The oesophageal string test: a novel, minimally invasive method measures mucosal inflammation in eosinophilic oesophagitis. Gut. 2012 Aug 15. [Epub ahead of print] PubMed PMID: 22895393
  • Aceves S, Hirano I, Furuta GT, Collins MH. Eosinophilic gastrointestinal diseases--clinically diverse and histopathologically confounding. Semin Immunopathol. 2012 Sep;34(5):715-31. PubMed PMID: 22842863
  • Ochkur SI, Kim JD, Protheroe CA, Colbert D, Condjella RM, Bersoux S, Helmers RA, Moqbel R, Lacy P, Kelly EA, Jarjour NN, Kern R, Peters A, Schleimer RP, Furuta GT, Nair P, Lee JJ, Lee NA. A sensitive high throughput ELISA for human eosinophil peroxidase: a specific assay to quantify eosinophil degranulation from patient-derived sources. J Immunol Methods. 2012 Oct 31;384(1-2):10-20. PubMed PMID: 22750539
  • Schroeder S, Fleischer DM, Masterson JC, Gelfand E, Furuta GT, Atkins D. Successful treatment of eosinophilic esophagitis with ciclesonide. J Allergy Clin Immunol. 2012 May;129(5):1419-21. PubMed PMID: 22480537
  • Kagalwalla AF, Akhtar N, Woodruff SA, Rea BA, Masterson JC, Mukkada V, Parashette KR, Du J, Fillon S, Protheroe CA, Lee JJ, Amsden K, Melin-Aldana H, Capocelli KE, Furuta GT, Ackerman SJ. Eosinophilic esophagitis: epithelial mesenchymal transition contributes to esophageal remodeling and reverses with treatment. J Allergy Clin Immunol. 2012 May;129(5):1387-1396.e7. PubMed PMID: 22465212
  • Straumann A, Aceves SS, Blanchard C, Collins MH, Furuta GT, Hirano I, Schoepfer AM, Simon D, Simon HU. Pediatric and adult eosinophilic esophagitis: similarities and differences. Allergy. 2012 Apr;67(4):477-90. PubMed PMID: 22313241
  • Spergel JM, Rothenberg ME, Collins MH, Furuta GT, Markowitz JE, Fuchs G 3rd, O'Gorman MA, Abonia JP, Young J, Henkel T, Wilkins HJ, Liacouras CA. Reslizumab in children and adolescents with eosinophilic esophagitis: results of a double-blind, randomized, placebo-controlled trial. J Allergy Clin Immunol. 2012 Feb;129(2):456-63, 463.e1-3. PubMed PMID: 22206777
  • Henry ML, Atkins D, Fleischer D, Pan Z, Ruybal J, Furuta GT. Factors contributing to adherence to dietary treatment of eosinophilic gastrointestinal diseases. J Pediatr Gastroenterol Nutr. 2012 Mar;54(3):430-2. PubMed PMID: 22094899
  • Aherne CM, Collins CB, Masterson JC, Tizzano M, Boyle TA, Westrich JA, Parnes JA, Furuta GT, Rivera-Nieves J, Eltzschig HK. Neuronal guidance molecule netrin-1 attenuates inflammatory cell trafficking during acute experimental colitis. Gut. 2012 May;61(5):695-705. PubMed PMID: 21813473
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Professional Memberships

  • American Gastroenterological Association , Member
  • North American Society of Pediatric GI, Hepatology and Nutrition, Executive Council
  • Crohn's and Colitis Foundation of America , Member
  • International Eosinophil Society, Member
  • Society of Pediatric Research , Member
  • The International Gastrointestinal Eosinophil Researchers, Chairman
  • American Pediatric Society (APS), Member

Practice Locations

Children's Hospital Colorado
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation
  • Children's Hospital Colorado

Specialty Information

Specialties
  • Pediatric Gastroenterology, Board Certification (2012)
Conditions & Treatments
  • Digestive System - Gastroenterology (Stomach, Bowel, General GI Problems)
  • Digestive System
Clinical Interests
The Gastrointestinal Eosinophilic Diseases Program will provide your child with multi-disciplinary care in a individualized fashion.

Care Philosophy
We provide individualized multi-disciplinary care for patients and families with eosinophilic gastrointestinal diseases.

Public Speaking
Yes
Eosinophilic GI diseases

General Information

Medical Schools:
  • MD, Baylor College of Medicine (1986)
Undergraduate Schools:
  • BA, University of Texas–Austin (TX) (1982)
Internships:
  • Baylor College of Medicine Program (1987)
Residency Programs:
  • Baylor College of Medicine Program, Chief Resident, Pediatrics (1990)
Fellowships:
  • Children's Hospital/Harvard Medical School Program, Pediatric Gastroenterology (1993)
Languages: English, German
Department: Pediatrics-Gastroenterology, Hepatology and Nutrition
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