Liping Yu, MD
Associate Research Professor, Pediatrics-Barbara Davis Center

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Languages: English
Department: Pediatrics-Barbara Davis Center

Publications

  • Guo Z, Kasinathan D, Merriman C, Nakayama M, Li H, Li H, Xu C, Wong GW, Yu L, Golson ML, Fu D. Cell-Surface Autoantibody Targets Zinc Transporter-8 (ZnT8) for In Vivo ß-Cell Imaging and Islet-Specific Therapies. Diabetes. 2023 Feb 1;72(2):184-195. PubMed PMID: 36448936
  • Gunna S, Singh M, Pandey R, Marak RSK, Aggarwal A, Mohanta B, Yu L, Bhatia E. Etiology, clinical characteristics and mortality among Indian patients with Addison's disease. Endocr Connect. 2023 Mar 1;12(3). PubMed PMID: 36625588
  • Jia X, Dong F, Pyle L, Michels AW, Yu L, Rewers M. Similar Time Course of Humoral Response to SARS-CoV-2 mRNA Vaccines in People With and Without Type 1 Diabetes. Diabetes Technol Ther. 2023 Jul;25(7):492-496. PubMed PMID: 36989496
  • Corrado MM, Jia X, Geno Rasmussen C, Pyle L, Yu L, Liu E, Stahl M, Rewers MJ. Previous SARS-CoV-2 Infection Is Not Associated With Increased Celiac Disease Autoimmunity in Children and Adolescents. Am J Gastroenterol. 2023 Sep 1;118(9):1698-1700. PubMed PMID: 37159249
  • Wenzlau JM, Gu Y, Michels A, Rewers M, Haskins K, Yu L. Identification of Autoantibodies to a Hybrid Insulin Peptide in Type 1 Diabetes. Diagnostics (Basel). 2023 Sep 4;13(17). PubMed PMID: 37685398
  • Redondo MJ, Harrall KK, Glueck DH, Tosur M, Uysal S, Muir A, Atkinson EG, Shapiro MR, Yu L, Winter WE, Weedon M, Brusko TM, Oram R, Vehik K, Hagopian W, Atkinson MA, Dabelea D. Diabetes Study of Children of Diverse Ethnicity and Race: Study design. Diabetes Metab Res Rev. 2023 Oct 27;:e3744. [Epub ahead of print] PubMed PMID: 37888801
  • Frost HM, Geno Rasmussen C, Shorrosh H, Pyle L, Bautista K, Frohnert BI, Stahl M, Simmons K, Steck AK, Jia X, Yu L, Rewers M. Prevalence of SARS-CoV-2 Antibodies Among Healthy Children From Colorado From 2020 to 2021: A Brief Report. J Prim Care Community Health. 2023 Jan-Dec;14:21501319231189147. PubMed PMID: 37501515
  • Jia X and Yu L. Effective assay technologies fit for large-scale population screening of type 1 diabetes. Frontier in Clin Diab and Healthcare. 2023. https://doi.org/10.3389/fcdhc.2022.1034698
  • Mitchell AM, Baschal EE, McDaniel KA, Simmons KM, Pyle L, Waugh K, Steck AK, Yu L, Gottlieb PA, Rewers MJ, Nakayama M, Michels AW. Temporal development of T cell receptor repertoires during childhood in health and disease. JCI Insight. 2022 Sep 22;7(18). PubMed PMID: 35998036
  • Jia X, He L, Miao D, Zhang C, Rewers M, Yu L. A High-throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19. J Vis Exp. 2022 Jul 5;(185). PubMed PMID: 35876559
  • Jia X, Toda K, He L, Miao D, Yamada S, Yu L, Kodama K. Expression-based Genome-wide Association Study Links OPN and IL1-RA With Newly Diagnosed Type 1 Diabetes in Children. J Clin Endocrinol Metab. 2022 Jun 16;107(7):1825-1832. PubMed PMID: 35460250
  • He L, Jia X, Rasmussen CG, Waugh K, Miao D, Dong F, Frohnert B, Steck AK, Simmons KM, Rewers M, Yu L. High-Throughput Multiplex Electrochemiluminescence Assay Applicable to General Population Screening for Type 1 Diabetes and Celiac Disease. Diabetes Technol Ther. 2022 Jul;24(7):502-509. PubMed PMID: 35238620
  • Steck AK, Dong F, Geno Rasmussen C, Bautista K, Sepulveda F, Baxter J, Yu L, Frohnert BI, Rewers MJ, Rewers M, Barbour A, Bautista K, Baxter J, Felipe-Morales D, Dong F, Dormond-Brooks P, Driscoll K, Frohnert B, Rasmussen CG, Gesualdo P, Hoffman M, Karban R, Sepulveda F, Shorrosh H, Simmons K, Steck A, Taki I, Waugh K, Yu L, Liu E, Gallant M, McQueen RB, Norris JM. CGM Metrics Predict Imminent Progression to Type 1 Diabetes: Autoimmunity Screening for Kids (ASK) Study. Diabetes Care. 2022 Feb 1;45(2):365-371. PubMed PMID: 34880069
  • Triolo TM, Pyle L, Broncucia H, Armstrong T, Yu L, Gottlieb PA, Steck AK. Association of High-Affinity Autoantibodies With Type 1 Diabetes High-Risk HLA Haplotypes. J Clin Endocrinol Metab. 2022 Mar 24;107(4):e1510-e1517. PubMed PMID: 34850014
  • Jia X, He L, Miao D, Waugh K, Geno Rasmussen C, Dong F, Steck AK, Rewers M, Yu L. High-affinity ZnT8 autoantibodies by electrochemiluminescence assay improve risk prediction for type 1 diabetes. J Clin Endocrinol Metab. 2021 Aug 3. [Epub ahead of print] PubMed PMID: 34343303
  • Gu Y, Jia X, Vartak T, Miao D, Dong F, Jerram ST, Rewers M, Ferrara A, Lawrence JM, Yu L, Leslie RD. Improving clinical utility of GAD65 autoantibodies by electrochemiluminescence assay and clinical phenotype when identifying autoimmune adult-onset diabetes. Diabetologia. 2021 Sep;64(9):2052-2060. PubMed PMID: 34272582
  • Gu Y, Merriman C, Guo Z, Jia X, Wenzlau J, Li H, Li H, Rewers M, Yu L, Fu D. Novel autoantibodies to the ß-cell surface epitopes of ZnT8 in patients progressing to type-1 diabetes. J Autoimmun. 2021 Aug;122:102677. PubMed PMID: 34130115
  • Jia X, Gesualdo P, Geno Rasmussen C, Alkanani AA, He L, Dong F, Rewers MJ, Michels AW, Yu L. Prevalence of SARS-CoV-2 Antibodies in Children and Adults with Type 1 Diabetes. Diabetes Technol Ther. 2021 Jul;23(7):517-521. PubMed PMID: 33544017
  • Landry LG, Anderson AM, Russ HA, Yu L, Kent SC, Atkinson MA, Mathews CE, Michels AW, Nakayama M. Proinsulin-Reactive CD4 T Cells in the Islets of Type 1 Diabetes Organ Donors. Front Endocrinol (Lausanne). 2021;12:622647. PubMed PMID: 33841327
  • Stahl MG, Geno Rasmussen C, Dong F, Waugh K, Norris JM, Baxter J, Yu L, Steck AK, Frohnert BI, Liu E, Rewers MJ. Mass Screening for Celiac Disease: The Autoimmunity Screening for Kids Study. Am J Gastroenterol. 2021 Jan 1;116(1):180-187. PubMed PMID: 32701732
  • Lawrence JM, Slezak JM, Quesenberry C, Li X, Yu L, Rewers M, Alexander JG, Takhar HS, Sridhar S, Albright A, Rolka DB, Saydah S, Imperatore G, Ferrara A. Incidence and predictors of type 1 diabetes among younger adults aged 20-45 years: The diabetes in young adults (DiYA) study. Diabetes Res Clin Pract. 2021 Jan;171:108624. PubMed PMID: 33338552
  • Triolo TM, Pyle L, Seligova S, Yu L, Simmons K, Gottlieb P, Evans-Molina C, Steck AK. Proinsulin:C-peptide ratio trajectories over time in relatives at increased risk of progression to type 1 diabetes. J Transl Autoimmun. 2021;4:100089. PubMed PMID: 33748733
  • Mitchell AM, Alkanani AA, McDaniel KA, Pyle L, Waugh K, Steck AK, Nakayama M, Yu L, Gottlieb PA, Rewers MJ, Michels AW. T-cell responses to hybrid insulin peptides prior to type 1 diabetes development. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6). PubMed PMID: 33542101
  • Cai Y, Yan J, Gu Y, Chen H, Chen Y, Xu X, Zhang M, Yu L, Zheng X, Yang T. Autoimmune thyroid disease correlates to islet autoimmunity on zinc transporter 8 autoantibody. Endocr Connect. 2021 May 19;10(5):534-542. PubMed PMID: 33909592
  • He L, Jia X, Yu L. Islet autoantibodies, assay specificity and disease specificity. Austin J Endocrinol and Diab. 2021. 8(2): 1086
  • Jia X, He L, Gu Y, High H, Yu L. A High-Throughput Electrochemiluminescence 7-Plex Assay Simultaneously Screening for Type 1 Diabetes and Multiple Autoimmune Diseases. J Vis Exp. 2020 May 29;(159). PubMed PMID: 32538917
  • Jia X, Gu Y, High H, Yu L. Islet autoantibodies in disease prediction and pathogenesis. Diabetol Int. 2020 Jan;11(1):6-10. PubMed PMID: 31949998
  • Miller RG, Yu L, Becker DJ, Orchard TJ, Costacou T. Older age of childhood type 1 diabetes onset is associated with islet autoantibody positivity >30 years later: the Pittsburgh Epidemiology of Diabetes Complications Study. Diabet Med. 2020 Aug;37(8):1386-1394. PubMed PMID: 32011014
  • Triolo TM, Pyle L, Seligova S, Yu L, Gottlieb PA, Steck AK. Risk of Islet and Celiac Autoimmunity in Cotwins of Probands With Type 1 Diabetes. J Endocr Soc. 2020 Jun 1;4(6):bvaa053. PubMed PMID: 32537543
  • Simmons KM, Mitchell AM, Alkanani AA, McDaniel KA, Baschal EE, Armstrong T, Pyle L, Yu L, Michels AW. Failed Genetic Protection: Type 1 Diabetes in the Presence of HLA-DQB1*06:02 . Diabetes. 2020 Aug;69(8):1763-1769. PubMed PMID: 32439825
  • Ward NC, Lui JB, Hernandez R, Yu L, Struthers M, Xie J, Santos Savio A, Dwyer CJ, Hsiung S, Yu A, Malek TR. Persistent IL-2 Receptor Signaling by IL-2/CD25 Fusion Protein Controls Diabetes in NOD Mice by Multiple Mechanisms. Diabetes. 2020 Nov;69(11):2400-2413. PubMed PMID: 32843568
  • Cepedaa JR, Sekhara NS, Hana J, Xiong W, Zhang N, Yu L, Dai S, Davidson HW, Kappler JW, An Z, and Zhang L. A monoclonal antibody with broad specificity for the ligands of insulin B:9-23 reactive T cells prevents spontaneous type 1 diabetes in mice.
  • He L, Jia X, Gu Y, Miao D, Waugh K, Geno C, Liu E, Rewers M, Yu L. Large-Scale Screening in General Population Children for Celiac Disease with a Multiplex Electrochemiluminescence (ECL) Assay. J Immunol Res. 2020;2020:8897656. PubMed PMID: 33426098
  • Gu Y, Zhao Z, Waugh K, Miao D, Jia X, Cheng J, Michels A, Rewers M, Yang T, Yu L. High-throughput multiplexed autoantibody detection to screen type 1 diabetes and multiple autoimmune diseases simultaneously. EBioMedicine. 2019 Sep;47:365-372. PubMed PMID: 31447394
  • Endesfelder D, Zu Castell W, Bonifacio E, Rewers M, Hagopian WA, She JX, Lernmark Å, Toppari J, Vehik K, Williams AJK, Yu L, Akolkar B, Krischer JP, Ziegler AG, Achenbach P. Time-Resolved Autoantibody Profiling Facilitates Stratification of Preclinical Type 1 Diabetes in Children. Diabetes. 2019 Jan;68(1):119-130. PubMed PMID: 30305370
  • Sahoo SK, Zaidi G, Vipin VP, Chapla A, Thomas N, Yu L, Asthana P, Bhatia E. Heterogeneity in the aetiology of diabetes mellitus in young adults: A prospective study from north India. Indian J Med Res. 2019 Apr;149(4):479-488. PubMed PMID: 31411171
  • Simmons KM, Fouts A, Pyle L, Clark P, Dong F, Yu L, Usmani-Brown S, Gottlieb P, Herold KC, Steck AK. Unmethylated Insulin as an Adjunctive Marker of Beta Cell Death and Progression to Type 1 Diabetes in Participants at Risk for Diabetes. Int J Mol Sci. 2019 Aug 8;20(16). PubMed PMID: 31398795
  • Simmons KM, Youngkin E, Alkanani A, Miao D, McDaniel K, Yu L, Michels AW. Screening children for type 1 diabetes-associated antibodies at community health fairs. Pediatr Diabetes. 2019 Nov;20(7):909-914. PubMed PMID: 31376227
  • Acevedo-Calado MJ, Pietropaolo SL, Morran MP, Schnell S, Vonberg AD, Verge CF, Gianani R, Becker DJ, Huang S, Greenbaum CJ, Yu L, Davidson HW, Michels AW, Rich SS, Pietropaolo M. Autoantibodies Directed Toward a Novel IA-2 Variant Protein Enhance Prediction of Type 1 Diabetes. Diabetes. 2019 Sep;68(9):1819-1829. PubMed PMID: 31167877
  • Zhao Z, Gu Y, Miao D, Hoffmeyer E, Liu Y, Yu L. Determination of Autoantibodies to Transglutaminase by Electrochemiluminescence (ECL) Assay. Methods Mol Biol. 2019;1901:197-203. PubMed PMID: 30539579
  • Merriman C, Huang Q, Gu W, Yu L, Fu D. A subclass of serum anti-ZnT8 antibodies directed to the surface of live pancreatic ß-cells. J Biol Chem. 2018 Jan 12;293(2):579-587. PubMed PMID: 29184000
  • Long AE, Wilson IV, Becker DJ, Libman IM, Arena VC, Wong FS, Steck AK, Rewers MJ, Yu L, Achenbach P, Casas R, Ludvigsson J, Williams AJK, Gillespie KM. Characteristics of slow progression to diabetes in multiple islet autoantibody-positive individuals from five longitudinal cohorts: the SNAIL study. Diabetologia. 2018 Jun;61(6):1484-1490. PubMed PMID: 29532109
  • Zhang L, Sosinowski T, Cox AR, Cepeda JR, Sekhar NS, Hartig SM, Miao D, Yu L, Pietropaolo M, Davidson HW. Chimeric antigen receptor (CAR) T cells targeting a pathogenic MHC class II:peptide complex modulate the progression of autoimmune diabetes. J Autoimmun. 2018 Aug 16. [Epub ahead of print] PubMed PMID: 30122420
  • Triolo TM, Fouts A, Pyle L, Yu L, Gottlieb PA, Steck AK. Identical and Nonidentical Twins: Risk and Factors Involved in Development of Islet Autoimmunity and Type 1 Diabetes. Diabetes Care. 2018 Jul 30. [Epub ahead of print] PubMed PMID: 30061316
  • Akturk HK, Alkanani A, Zhao Z, Yu L, Michels AW. PD-1 Inhibitor Immune-Related Adverse Events in Patients With Preexisting Endocrine Autoimmunity. J Clin Endocrinol Metab. 2018 Oct 1;103(10):3589-3592. PubMed PMID: 30124874
  • Endesfelder D, Castell WZ, Bonifacio E, Rewers M, Hagopian WA, She JX, Lernmark Å, Toppari J, Vehik K, Williams AJK, Yu L, Akolkar B, Krischer JP, Ziegler AG, Achenbach P. Time-Resolved Autoantibody Profiling Facilitates Stratification of Preclinical Type 1 Diabetes in Children. Diabetes. 2018 Oct 10. [Epub ahead of print] PubMed PMID: 30305370
  • Pugliese A, Boulware D, Yu L, Babu S, Steck AK, Becker D, Rodriguez H, DiMeglio L, Evans-Molina C, Harrison LC, Schatz D, Palmer JP, Greenbaum C, Eisenbarth GS, Sosenko JM. HLA-DRB1*15:01-DQA1*01:02-DQB1*06:02 Haplotype Protects Autoantibody-Positive Relatives From Type 1 Diabetes Throughout the Stages of Disease Progression. Diabetes. 2016 Apr;65(4):1109-19. PubMed PMID: 26822082
  • Kim JH, Furrow E, Ritt MG, Utz PJ, Robinson WH, Yu L, Eckert A, Stuebner K, O'Brien TD, Steinman L, Modiano JF. Anti-Insulin Immune Responses Are Detectable in Dogs with Spontaneous Diabetes. PLoS One. 2016 Mar 31;11(3):e0152397. PubMed PMID: 27031512
  • Zhao Z, Zou J, Zhao L, Cheng Y, Cai H, Li M, Liu E, Yu L, Liu Y. Celiac Disease Autoimmunity in Patients with Autoimmune Diabetes and Thyroid Disease among Chinese Population. PLoS One. 2016 Jul 18;11(7):e0157510. PubMed PMID: 27427767
  • Wasserfall C, Montgomery E, Yu L, Michels A, Gianani R, Pugliese A, Nierras C, Kaddis JS, Schatz DA, Bonifacio E, Atkinson MA. Validation of a rapid type 1 diabetes autoantibody screening assay for community-based screening of organ donors to identify subjects at increased risk for the disease. Clin Exp Immunol. 2016 Jul;185(1):33-41. PubMed PMID: 27029857
  • Fouts A, Pyle L, Yu L, Miao D, Michels A, Krischer J, Sosenko J, Gottlieb P, Steck AK. Do Electrochemiluminescence Assays Improve Prediction of Time to Type 1 Diabetes in Autoantibody-Positive TrialNet Subjects?. Diabetes Care. 2016 Oct;39(10):1738-44. PubMed PMID: 27456836
  • Simmons KM, Alkanani AK, McDaniel KA, Goyne C, Miao D, Zhao Z, Yu L, Michels AW. Islet Autoantibody Measurements from Dried Blood Spots on Filter Paper Strongly Correlate to Serum Levels. PLoS One. 2016 Nov 15;11(11):e0166213. PubMed PMID: 27846247
  • Sunni M, Noble JA, Yu L, Mahamed Z, Lane JA, Dhunkal AM, Bellin MD, Nathan B, Kyllo J, Abuzzahab MJ, Gottlieb PA, Babu S, Armstrong T, Moran A. Predominance of DR3 in Somali children with type 1 diabetes in the twin cities, Minnesota. Pediatr Diabetes. 2016 Feb 8. [Epub ahead of print] PubMed PMID: 26854192
  • Xu X, Gu Y, Bian L, Shi Y, Cai Y, Chen Y, Chen H, Qian L, Wu X, Xu K, Mallone R, Davidson HW, Yu L, She J, Zhang M, Yang T. Characterization of immune response to novel HLA-A2-restricted epitopes from zinc transporter 8 in type 1 diabetes. Vaccine. 2016 Feb 3;34(6):854-62. PubMed PMID: 26541133
  • Miao D, Steck AK, Zhang L, Guyer KM, Jiang L, Armstrong T, Muller SM, Krischer J, Rewers M, Yu L. Electrochemiluminescence assays for insulin and glutamic acid decarboxylase autoantibodies improve prediction of type 1 diabetes risk. Diabetes Technol Ther. 2015 Feb;17(2):119-27. PubMed PMID: 25562486
  • Nakayama M, McDaniel K, Fitzgerald-Miller L, Kiekhaefer C, Snell-Bergeon JK, Davidson HW, Rewers M, Yu L, Gottlieb P, Kappler JW, Michels A. Regulatory vs. inflammatory cytokine T-cell responses to mutated insulin peptides in healthy and type 1 diabetic subjects. Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4429-34. PubMed PMID: 25831495
  • Brorsson CA, Onengut S, Chen WM, Wenzlau J, Yu L, Baker P, Williams AJ, Bingley PJ, Hutton JC, Eisenbarth GS, Concannon P, Rich SS, Pociot F. Novel Association Between Immune-Mediated Susceptibility Loci and Persistent Autoantibody Positivity in Type 1 Diabetes. Diabetes. 2015 Aug;64(8):3017-27. PubMed PMID: 25829454
  • Bellin MD, Moran A, Wilhelm JJ, O'Brien TD, Gottlieb PA, Yu L, Dunn TB. Development of Autoimmune-Mediated ß Cell Failure After Total Pancreatectomy With Autologous Islet Transplantation. Am J Transplant. 2015 Jul;15(7):1991-4. PubMed PMID: 25765064
  • Bingley PJ, Rafkin LE, Matheson D, Steck AK, Yu L, Henderson C, Beam CA, Boulware DC. Use of Dried Capillary Blood Sampling for Islet Autoantibody Screening in Relatives: A Feasibility Study. Diabetes Technol Ther. 2015 Dec;17(12):867-71. PubMed PMID: 26375197
  • Akazawa S, Kobayashi M, Kuriya G, Horie I, Yu L, Yamasaki H, Okita M, Nagayama Y, Matsuyama T, Akbari M, Yui K, Kawakami A, Abiru N. Haploinsufficiency of interferon regulatory factor 4 strongly protects against autoimmune diabetes in NOD mice. Diabetologia. 2015 Nov;58(11):2606-14. PubMed PMID: 26271342
  • Xu X, Gu Y, Bian L, Shi Y, Cai Y, Chen Y, Chen H, Qian L, Wu X, Xu K, Mallone R, Davidson HW, Yu L, She J, Zhang M, Yang T. Characterization of immune response to novel HLA-A2-restricted epitopes from zinc transporter 8 in type 1 diabetes. Vaccine. 2015 Nov 3. [Epub ahead of print] PubMed PMID: 26541133
  • Gesualdo PD, Bautista KA, Waugh KC, Yu L, Norris JM, Rewers MJ, Baxter J. Feasibility of screening for T1D and celiac disease in a pediatric clinic setting. Pediatr Diabetes. 2015 Aug 6. [Epub ahead of print] PubMed PMID: 26251221
  • Zhang L, Crawford F, Yu L, Michels A, Nakayama M, Davidson HW, Kappler JW, Eisenbarth GS. Monoclonal antibody blocking the recognition of an insulin peptide-MHC complex modulates type 1 diabetes. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2656-61. PubMed PMID: 24550292
  • Liu E, McDaniel K, Case S, Yu L, Gerhartz B, Ostermann N, Fankhauser G, Hungerford V, Zou C, Luyten M, Seidl KJ, Michels AW. Exploring T cell reactivity to gliadin in young children with newly diagnosed celiac disease. Autoimmune Dis. 2014;2014:927190. PubMed PMID: 24724018
  • Zhang L, Londono P, Yu L, Grimes S, Blackburn P, Gottlieb P, Eisenbarth GS. MAS-1 adjuvant immunotherapy generates robust Th2 type and regulatory immune responses providing long-term protection from diabetes in late-stage pre-diabetic NOD mice. Autoimmunity. 2014 Aug;47(5):341-50. PubMed PMID: 24783965
  • Roep BO, Solvason N, Gottlieb PA, Abreu JR, Harrison LC, Eisenbarth GS, Yu L, Leviten M, Hagopian WA, Buse JB, von Herrath M, Quan J, King RS, Robinson WH, Utz PJ, Garren H, BHT-3021 Investigators, Steinman L. Plasmid-encoded proinsulin preserves C-peptide while specifically reducing proinsulin-specific CD8? T cells in type 1 diabetes. Sci Transl Med. 2013 Jun 26;5(191):191ra82. PubMed PMID: 23803704
  • Sosenko JM, Skyler JS, Palmer JP, Krischer JP, Yu L, Mahon J, Beam CA, Boulware DC, Rafkin L, Schatz D, Eisenbarth G, Type 1 Diabetes TrialNet Study Group, Diabetes Prevention Trial-Type 1 Study Group. The prediction of type 1 diabetes by multiple autoantibody levels and their incorporation into an autoantibody risk score in relatives of type 1 diabetic patients. Diabetes Care. 2013 Sep;36(9):2615-20. PubMed PMID: 23818528
  • Kuriya G, Uchida T, Akazawa S, Kobayashi M, Nakamura K, Satoh T, Horie I, Kawasaki E, Yamasaki H, Yu L, Iwakura Y, Sasaki H, Nagayama Y, Kawakami A, Abiru N. Double deficiency in IL-17 and IFN-? signalling significantly suppresses the development of diabetes in the NOD mouse. Diabetologia. 2013 Aug;56(8):1773-80. PubMed PMID: 23699989
  • Xu X, Shi Y, Cai Y, Zhang Q, Yang F, Chen H, Gu Y, Zhang M, Yu L, Yang T. Inhibition of Increased Circulating Tfh Cell by Anti-CD20 Monoclonal Antibody in Patients with Type 1 Diabetes. PLoS One. 2013 Nov 20;8(11):e79858. PubMed PMID: 24278195
  • Yu L, Miao D, Scrimgeour L, Johnson K, Rewers M, Eisenbarth GS. Distinguishing persistent insulin autoantibodies with differential risk: nonradioactive bivalent proinsulin/insulin autoantibody assay. Diabetes. 2012 Jan;61(1):179-86. PubMed PMID: 22124462
  • Yu L, Boulware DC, Beam CA, Hutton JC, Wenzlau JM, Greenbaum CJ, Bingley PJ, Krischer JP, Sosenko JM, Skyler JS, Eisenbarth GS, Mahon JL, Type 1 Diabetes TrialNet Study Group. Zinc transporter-8 autoantibodies improve prediction of type 1 diabetes in relatives positive for the standard biochemical autoantibodies. Diabetes Care. 2012 Jun;35(6):1213-8. PubMed PMID: 22446173
  • Baker PR, Nanduri P, Gottlieb PA, Yu L, Klingensmith GJ, Eisenbarth GS, Barker JM. Predicting the onset of Addison's disease: ACTH, renin, cortisol and 21-hydroxylase autoantibodies. Clin Endocrinol (Oxf). 2012 May;76(5):617-24. PubMed PMID: 22066755
  • Baker P, Fain P, Kahles H, Yu L, Hutton J, Wenzlau J, Rewers M, Badenhoop K, Eisenbarth G. Genetic determinants of 21-hydroxylase autoantibodies amongst patients of the Type 1 Diabetes Genetics Consortium. J Clin Endocrinol Metab. 2012 Aug;97(8):E1573-8. PubMed PMID: 22723331
  • Gu Y, Zhang M, Chen H, Wang Z, Xing C, Yang H, Xu X, Liu Y, Zhou Z, Yu L, Hutton J, Eisenbarth G, Yang T. Discordant association of islet autoantibodies with high-risk HLA genes in Chinese type 1 diabetes. Diabetes Metab Res Rev. 2011 Nov;27(8):899-905. PubMed PMID: 22069282
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Practice Locations

Barbara Davis Center for Diabetes Pediatric Clinic - CU Anschutz Medical Campus
1775 Aurora Ct
Suite A140
Aurora, CO 80045
303-724-2323

Hospital Affiliation
  • Children's Hospital Colorado

Specialty Information

Specialties
  • Pediatric Endocrinology

General Information

Languages: English
Department: Pediatrics-Barbara Davis Center
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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