Robin Shandas, PhD
Professor, University of Colorado - Denver

Photo
Graduate Schools :
  • MSc, University of California, San Diego (1991)
  • PhD, University of California, San Diego (1993)
Undergraduate School:
  • BS, University of California System (CA) (1987)
Languages: English
Department: University of Colorado - Denver

Professional Titles

  • Professor, University of Colorado - Denver
  • Distinguished Professor of Bioengineering
  • Chair, Dept. of Bioengineering
  • Director, Center for Bioengineering
  • Professor of Pediatrics (Cardiology)

Recognition & Awards

  • Distinguished Professor of Bioengineering, University of Colorado (2019)
    CU Distinguished Professors are faculty members who demonstrate exemplary performance in research or creative work, a record of excellence in classroom teaching and supervision of individual learning, and outstanding service to the profession, the university and its affiliates.

Teaching

  • Professor of Bioengineering (2020)
    College of Engineering and Applied Science, University of Colorado - Denver
    Medical Device Design and Entrepreneurship Hemodynamics Medical Ultrasound and Medical Imaging
  • Professor of Pediatrics (Cardiology) (2020)
    School of Medicine, Pediatrics
    Congenital Heart Disease Cardiac Echocardiography and Cardiac Imaging Pediatric Cardiac Surgery

Publications

  • Peña B, Maldonado M, Bonham AJ, Aguado BA, Dominguez-Alfaro A, Laughter M, Rowland TJ, Bardill J, Farnsworth NL, Alegret Ramon N, Taylor MRG, Anseth KS, Prato M, Shandas R, McKinsey TA, Park D, Mestroni L. Gold Nanoparticle-Functionalized Reverse Thermal Gel for Tissue Engineering Applications. ACS Appl Mater Interfaces. 2019 May 22;11(20):18671-18680. PubMed PMID: 31021594
  • Lee DJ, Cavasin MA, Rocker AJ, Soranno DE, Meng X, Shandas R, Park D. An injectable sulfonated reversible thermal gel for therapeutic angiogenesis to protect cardiac function after a myocardial infarction. J Biol Eng. 2019;13:6. PubMed PMID: 30675179
  • Dufva MJ, Truong U, Tiwari P, Ivy DD, Shandas R, Kheyfets VO. Left ventricular torsion rate and the relation to right ventricular function in pediatric pulmonary arterial hypertension. Pulm Circ. 2018 Jul-Sep;8(3):2045894018791352. PubMed PMID: 30003835
  • Gates PE, Gurung A, Mazzaro L, Aizawa K, Elyas S, Strain WD, Shore AC, Shandas R. Measurement of Wall Shear Stress Exerted by Flowing Blood in the Human Carotid Artery: Ultrasound Doppler Velocimetry and Echo Particle Image Velocimetry. Ultrasound Med Biol. 2018 Jul;44(7):1392-1401. PubMed PMID: 29678322
  • Madhavan K, Frid MG, Hunter K, Shandas R, Stenmark KR, Park D. Development of an electrospun biomimetic polyurea scaffold suitable for vascular grafting. J Biomed Mater Res B Appl Biomater. 2018 Jan;106(1):278-290. PubMed PMID: 28130878
  • Lee DJ, Rocker AJ, Bardill JR, Shandas R, Park D. A sulfonated reversible thermal gel for the spatiotemporal control of VEGF delivery to promote therapeutic angiogenesis. J Biomed Mater Res A. 2018 Dec;106(12):3053-3064. PubMed PMID: 30295997
  • DeBoer EM, Wagner J, Kroehl ME, Albietz J, Shandas R, Deterding RR, Rustici MJ. Three-Dimensional Printed Pediatric Airway Model Improves Novice Learners' Flexible Bronchoscopy Skills With Minimal Direct Teaching From Faculty. Simul Healthc. 2018 Aug;13(4):284-288. PubMed PMID: 29381588
  • Peña B, Bosi S, Aguado BA, Borin D, Farnsworth NL, Dobrinskikh E, Rowland TJ, Martinelli V, Jeong M, Taylor MRG, Long CS, Shandas R, Sbaizero O, Prato M, Anseth KS, Park D, Mestroni L. Injectable Carbon Nanotube-Functionalized Reverse Thermal Gel Promotes Cardiomyocytes Survival and Maturation. ACS Appl Mater Interfaces. 2017 Sep 20;9(37):31645-31656. PubMed PMID: 28895403
  • Govindarajan T, Shandas R. Shape Memory Polymers Containing Higher Acrylate Content Display Increased Endothelial Cell Attachment. Polymers (Basel). 2017 Nov;9(11). PubMed PMID: 29707382
  • Gurung A, Gates PE, Mazzaro L, Fulford J, Zhang F, Barker AJ, Hertzberg J, Aizawa K, Strain WD, Elyas S, Shore AC, Shandas R. Echo Particle Image Velocimetry for Estimation of Carotid Artery Wall Shear Stress: Repeatability, Reproducibility and Comparison with Phase-Contrast Magnetic Resonance Imaging. Ultrasound Med Biol. 2017 Aug;43(8):1618-1627. PubMed PMID: 28501327
  • Schäfer M, Ivy DD, Barker AJ, Kheyfets V, Shandas R, Abman SH, Hunter KS, Truong U. Characterization of CMR-derived haemodynamic data in children with pulmonary arterial hypertension. Eur Heart J Cardiovasc Imaging. 2017 Apr 1;18(4):424-431. PubMed PMID: 27444679
  • Kheyfets VO, Sucharov CC, Truong U, Dunning J, Hunter K, Ivy D, Miyamoto S, Shandas R. Circulating miRNAs in Pediatric Pulmonary Hypertension Show Promise as Biomarkers of Vascular Function. Oxid Med Cell Longev. 2017;2017:4957147. PubMed PMID: 28819545
  • Kheyfets VO, Schafer M, Podgorski CA, Schroeder JD, Browning J, Hertzberg J, Buckner JK, Hunter KS, Shandas R, Fenster BE. 4D magnetic resonance flow imaging for estimating pulmonary vascular resistance in pulmonary hypertension. J Magn Reson Imaging. 2016 Oct;44(4):914-22. PubMed PMID: 27173445
  • Peña B, Martinelli V, Jeong M, Bosi S, Lapasin R, Taylor MR, Long CS, Shandas R, Park D, Mestroni L. Biomimetic Polymers for Cardiac Tissue Engineering. Biomacromolecules. 2016 May 9;17(5):1593-601. PubMed PMID: 27073119
  • Schäfer M, Browning J, Schroeder JD, Shandas R, Kheyfets VO, Buckner JK, Hunter KS, Hertzberg JR, Fenster BE. Vorticity is a marker of diastolic ventricular interdependency in pulmonary hypertension. Pulm Circ. 2016 Mar;6(1):46-54. PubMed PMID: 27162613
  • Schäfer M, Kheyfets VO, Schroeder JD, Dunning J, Shandas R, Buckner JK, Browning J, Hertzberg J, Hunter KS, Fenster BE. Main pulmonary arterial wall shear stress correlates with invasive hemodynamics and stiffness in pulmonary hypertension. Pulm Circ. 2016 Mar;6(1):37-45. PubMed PMID: 27076906
  • Humphries SM, Hunter KS, Shandas R, Deterding RR, DeBoer EM. Erratum to: Analysis of pediatric airway morphology using statistical shape modeling. Med Biol Eng Comput. 2016 Jun;54(6):913. PubMed PMID: 26815534
  • Humphries SM, Hunter KS, Shandas R, Deterding RR, DeBoer EM. Analysis of pediatric airway morphology using statistical shape modeling. Med Biol Eng Comput. 2016 Jun;54(6):899-911. PubMed PMID: 26718559
  • Kheyfets VO, Dunning J, Truong U, Ivy D, Hunter K, Shandas R. A Zero-Dimensional Model and Protocol for Simulating Patient-Specific Pulmonary Hemodynamics From Limited Clinical Data. J Biomech Eng. 2016 Dec 1;138(12). PubMed PMID: 27684888
  • Peña B, Shandas R, Park D. A heparin-mimicking reverse thermal gel for controlled delivery of positively charged proteins. J Biomed Mater Res A. 2015 Jun;103(6):2102-8. PubMed PMID: 25294242
  • Kheyfets VO, Dunning J, Truong U, Ivy DD, Hunter KA, Shandas R. Assessment of N-terminal prohormone B-type natriuretic peptide as a measure of vascular and ventricular function in pediatric pulmonary arterial hypertension. Pulm Circ. 2015 Dec;5(4):658-66. PubMed PMID: 26697173
  • Zimkowski MM, Rentschler ME, Schoen JA, Mandava N, Shandas R. Biocompatibility and tissue integration of a novel shape memory surgical mesh for ventral hernia: in vivo animal studies. J Biomed Mater Res B Appl Biomater. 2014 Jul;102(5):1093-100. PubMed PMID: 24327401
  • Yan F, Li X, Jiang C, Jin Q, Zhang Z, Shandas R, Wu J, Liu X, Zheng H. A novel microfluidic chip for assessing dynamic adhesion behavior of cell-targeting microbubbles. Ultrasound Med Biol. 2014 Jan;40(1):148-57. PubMed PMID: 24210864
  • Aurand ER, Wagner JL, Shandas R, Bjugstad KB. Hydrogel formulation determines cell fate of fetal and adult neural progenitor cells. Stem Cell Res. 2014 Jan;12(1):11-23. PubMed PMID: 24141109
  • Yunker BE, Dodd GD, Chen SJ, Chang S, Lanning CJ, Scherzinger AL, Shandas R, Feng Y, Hunter KS. The design and fabrication of two portal vein flow phantoms by different methods. Med Phys. 2014 Feb;41(2):023701. PubMed PMID: 24506653
  • Milgroom A, Intrator M, Madhavan K, Mazzaro L, Shandas R, Liu B, Park D. Mesoporous silica nanoparticles as a breast-cancer targeting ultrasound contrast agent. Colloids Surf B Biointerfaces. 2014 Apr 1;116:652-7. PubMed PMID: 24269054
  • Wagner JL, Shandas R, Lanning CJ. Extubation force depends upon angle of force application and fixation technique: a study of 7 methods. BMC Anesthesiol. 2014;14:74. PubMed PMID: 25214815
  • Hunter KS, Fjield T, Heitzmann H, Shandas R, Kahook MY. Characterization of micro-invasive trabecular bypass stents by ex vivo perfusion and computational flow modeling. Clin Ophthalmol. 2014;8:499-506. PubMed PMID: 24648713
  • Zimkowski MM, Rentschler ME, Schoen J, Rech BA, Mandava N, Shandas R. Integrating a novel shape memory polymer into surgical meshes decreases placement time in laparoscopic surgery: an in vitro and acute in vivo study. J Biomed Mater Res A. 2013 Sep;101(9):2613-20. PubMed PMID: 23412974
  • Yunker BE, Cordes D, Scherzinger AL, Dodd GD, Shandas R, Feng Y, Hunter KS. An investigation of industrial molding compounds for use in 3D ultrasound, MRI, and CT imaging phantoms. Med Phys. 2013 May;40(5):052905. PubMed PMID: 23635298
  • Yan F, Li L, Deng Z, Jin Q, Chen J, Yang W, Yeh CK, Wu J, Shandas R, Liu X, Zheng H. Paclitaxel-liposome-microbubble complexes as ultrasound-triggered therapeutic drug delivery carriers. J Control Release. 2013 Mar 28;166(3):246-55. PubMed PMID: 23306023
  • Scott D, Tan Y, Shandas R, Stenmark KR, Tan W. High pulsatility flow stimulates smooth muscle cell hypertrophy and contractile protein expression. Am J Physiol Lung Cell Mol Physiol. 2013 Jan 1;304(1):L70-81. PubMed PMID: 23087017
  • Su Z, Tan W, Shandas R, Hunter KS. Influence of distal resistance and proximal stiffness on hemodynamics and RV afterload in progression and treatments of pulmonary hypertension: a computational study with validation using animal models. Comput Math Methods Med. 2013;2013:618326. PubMed PMID: 24367392
  • Jin Q, Wang Z, Yan F, Deng Z, Ni F, Wu J, Shandas R, Liu X, Zheng H. A novel cationic microbubble coated with stearic acid-modified polyethylenimine to enhance DNA loading and gene delivery by ultrasound. PLoS One. 2013;8(9):e76544. PubMed PMID: 24086748
  • Su Z, Hunter KS, Shandas R. Impact of pulmonary vascular stiffness and vasodilator treatment in pediatric pulmonary hypertension: 21 patient-specific fluid-structure interaction studies. Comput Methods Programs Biomed. 2012 Nov;108(2):617-28. PubMed PMID: 21975085
  • Nair DP, Cramer NB, McBride MK, Gaipa JC, Shandas R, Bowman CN. Enhanced Two-Stage Reactive Polymer Network Forming Systems. Polymer (Guildf). 2012 May 25;53(12):2429-2434. PubMed PMID: 22798700
  • Olson JL, Shandas R, Erlanger M. Development of a minimally invasive, injectable, shape memory suture and delivery system. Ann Biomed Eng. 2012 Jul;40(7):1520-9. PubMed PMID: 22258886
  • Tian L, Lammers SR, Kao PH, Albietz JA, Stenmark KR, Qi HJ, Shandas R, Hunter KS. Impact of residual stretch and remodeling on collagen engagement in healthy and pulmonary hypertensive calf pulmonary arteries at physiological pressures. Ann Biomed Eng. 2012 Jul;40(7):1419-33. PubMed PMID: 22237861
  • Lammers S, Scott D, Hunter K, Tan W, Shandas R, Stenmark KR. Mechanics and Function of the Pulmonary Vasculature: Implications for Pulmonary Vascular Disease and Right Ventricular Function. Compr Physiol. 2012 Jan 1;2(1):295-319. PubMed PMID: 23487595
  • Lammers S, Scott D, Hunter K, Tan W, Shandas R, Stenmark KR. Mechanics and function of the pulmonary vasculature: implications for pulmonary vascular disease and right ventricular function. Compr Physiol. 2012 Jan;2(1):295-319. PubMed PMID: 23728987
  • Scott-Drechsel D, Su Z, Hunter K, Li M, Shandas R, Tan W. A new flow co-culture system for studying mechanobiology effects of pulse flow waves. Cytotechnology. 2012 Dec;64(6):649-66. PubMed PMID: 22526489
  • Yan F, Li X, Jin Q, Chen J, Shandas R, Wu J, Li L, Ling T, Yang W, Chen Y, Liu X, Zheng H. Ultrasonic imaging of endothelial CD81 expression using CD81-targeted contrast agents in in vitro and in vivo studies. Ultrasound Med Biol. 2012 Apr;38(4):670-80. PubMed PMID: 22341598
  • Tian L, Lammers SR, Kao PH, Reusser M, Stenmark KR, Hunter KS, Qi HJ, Shandas R. Linked opening angle and histological and mechanical aspects of the proximal pulmonary arteries of healthy and pulmonary hypertensive rats and calves. Am J Physiol Heart Circ Physiol. 2011 Nov;301(5):H1810-8. PubMed PMID: 21856906
  • Kao PH, Lammers SR, Tian L, Hunter K, Stenmark KR, Shandas R, Qi HJ. A microstructurally driven model for pulmonary artery tissue. J Biomech Eng. 2011 May;133(5):051002. PubMed PMID: 21599093
  • Zhang F, Lanning C, Mazzaro L, Barker AJ, Gates PE, Strain WD, Fulford J, Gosling OE, Shore AC, Bellenger NG, Rech B, Chen J, Chen J, Shandas R. In vitro and preliminary in vivo validation of echo particle image velocimetry in carotid vascular imaging. Ultrasound Med Biol. 2011 Mar;37(3):450-64. PubMed PMID: 21316562
  • Hunter KS, Lammers SR, Shandas R. Pulmonary vascular stiffness: measurement, modeling, and implications in normal and hypertensive pulmonary circulations. Compr Physiol. 2011 Jul;1(3):1413-35. PubMed PMID: 23733649
  • Niu L, Qian M, Yan L, Yu W, Jiang B, Jin Q, Wang Y, Shandas R, Liu X, Zheng H. Real-time texture analysis for identifying optimum microbubble concentration in 2-D ultrasonic particle image velocimetry. Ultrasound Med Biol. 2011 Aug;37(8):1280-91. PubMed PMID: 21684062
  • Lindley EM, Jaafar S, Noshchenko A, Baldini T, Nair DP, Shandas R, Burger EL, Patel VV. Nucleus replacement device failure: a case report and biomechanical study. Spine (Phila Pa 1976). 2010 Oct 15;35(22):E1241-7. PubMed PMID: 20881660
  • Nair DP, Cramer NB, Scott TF, Bowman CN, Shandas R. Photopolymerized Thiol-Ene Systems as Shape Memory Polymers. Polymer (Guildf). 2010 Sep 3;51(19):4383-4389. PubMed PMID: 21072253
  • Barker AJ, Lanning C, Shandas R. Quantification of hemodynamic wall shear stress in patients with bicuspid aortic valve using phase-contrast MRI. Ann Biomed Eng. 2010 Mar;38(3):788-800. PubMed PMID: 19953319
  • Tian L, Hunter KS, Kirby KS, Ivy DD, Shandas R. Measurement uncertainty in pulmonary vascular input impedance and characteristic impedance estimated from pulsed-wave Doppler ultrasound and pressure: clinical studies on 57 pediatric patients. Physiol Meas. 2010 Jun;31(6):729-48. PubMed PMID: 20410558
  • Hunter KS, Feinstein JA, Ivy DD, Shandas R. Computational Simulation of the Pulmonary Arteries and its Role in the Study of Pediatric Pulmonary Hypertension. Prog Pediatr Cardiol. 2010 Dec 1;30(1-2):63-69. PubMed PMID: 21499523
  • Kao PH, Lammers SR, Hunter K, Stenmark KR, Shandas R, Qi HJ. Constitutive Modeling of Anisotropic Finite-Deformation Hyperelastic Behaviors of Soft Materials Reinforced by Tortuous Fibers. Int J Struct Changes Sol. 2010 Apr;2(1):19-29. PubMed PMID: 21822502
  • Hunter KS, Albietz JA, Lee PF, Lanning CJ, Lammers SR, Hofmeister SH, Kao PH, Qi HJ, Stenmark KR, Shandas R. In vivo measurement of proximal pulmonary artery elastic modulus in the neonatal calf model of pulmonary hypertension: development and ex vivo validation. J Appl Physiol (1985). 2010 Apr;108(4):968-75. PubMed PMID: 20093662
  • Chen J, Hunter KS, Shandas R. Wave scattering from encapsulated microbubbles subject to high-frequency ultrasound: contribution of higher-order scattering modes. J Acoust Soc Am. 2009 Oct;126(4):1766-75. PubMed PMID: 19813791
  • Li M, Scott DE, Shandas R, Stenmark KR, Tan W. High pulsatility flow induces adhesion molecule and cytokine mRNA expression in distal pulmonary artery endothelial cells. Ann Biomed Eng. 2009 Jun;37(6):1082-92. PubMed PMID: 19340571
  • Lacour-Gayet FG, Lanning CJ, Stoica S, Wang R, Rech BA, Goldberg S, Shandas R. An artificial right ventricle for failing fontan: in vitro and computational study. Ann Thorac Surg. 2009 Jul;88(1):170-6. PubMed PMID: 19559219
  • Liu J, Oakley C, Shandas R. Capacitive micromachined ultrasonic transducers using commercial multi-user MUMPs process: capability and limitations. Ultrasonics. 2009 Dec;49(8):765-73. PubMed PMID: 19640557
  • Li M, Stenmark KR, Shandas R, Tan W. Effects of pathological flow on pulmonary artery endothelial production of vasoactive mediators and growth factors. J Vasc Res. 2009;46(6):561-71. PubMed PMID: 19571576
  • Lammers SR, Kao PH, Qi HJ, Hunter K, Lanning C, Albietz J, Hofmeister S, Mecham R, Stenmark KR, Shandas R. Changes in the structure-function relationship of elastin and its impact on the proximal pulmonary arterial mechanics of hypertensive calves. Am J Physiol Heart Circ Physiol. 2008 Oct;295(4):H1451-9. PubMed PMID: 18660454
  • Hunter KS, Gross JK, Lanning CJ, Kirby KS, Dyer KL, Ivy DD, Shandas R. Noninvasive methods for determining pulmonary vascular function in children with pulmonary arterial hypertension: application of a mechanical oscillator model. Congenit Heart Dis. 2008 Mar-Apr;3(2):106-16. PubMed PMID: 18380759
  • Liu L, Zheng H, Williams L, Zhang F, Wang R, Hertzberg J, Shandas R. Development of a custom-designed echo particle image velocimetry system for multi-component hemodynamic measurements: system characterization and initial experimental results. Phys Med Biol. 2008 Mar 7;53(5):1397-412. PubMed PMID: 18296769
  • Yakacki CM, Lyons MB, Rech B, Gall K, Shandas R. Cytotoxicity and thermomechanical behavior of biomedical shape-memory polymer networks post-sterilization. Biomed Mater. 2008 Mar;3(1):015010. PubMed PMID: 18458497
  • Drexler ES, Bischoff JE, Slifka AJ, McCowan CN, Quinn TP, Shandas R, Ivy DD, Stenmark KR. Stiffening of the Extrapulmonary Arteries From Rats in Chronic Hypoxic Pulmonary Hypertension. J Res Natl Inst Stand Technol. 2008 Jul-Aug;113(4):239-49. PubMed PMID: 27096124
  • Hunter KS, Lee PF, Lanning CJ, Ivy DD, Kirby KS, Claussen LR, Chan KC, Shandas R. Pulmonary vascular input impedance is a combined measure of pulmonary vascular resistance and stiffness and predicts clinical outcomes better than pulmonary vascular resistance alone in pediatric patients with pulmonary hypertension. Am Heart J. 2008 Jan;155(1):166-74. PubMed PMID: 18082509
  • Yakacki CM, Shandas R, Safranski D, Ortega AM, Sassaman K, Gall K. Strong, Tailored, Biocompatible Shape-Memory Polymer Networks. Adv Funct Mater. 2008 Aug 22;18(16):2428-2435. PubMed PMID: 19633727
  • Yakacki CM, Shandas R, Lanning C, Rech B, Eckstein A, Gall K. Unconstrained recovery characterization of shape-memory polymer networks for cardiovascular applications. Biomaterials. 2007 May;28(14):2255-63. PubMed PMID: 17296222
  • Zhang Y, Dunn ML, Hunter KS, Lanning C, Ivy DD, Claussen L, Chen SJ, Shandas R. Application of a microstructural constitutive model of the pulmonary artery to patient-specific studies: validation and effect of orthotropy. J Biomech Eng. 2007 Apr;129(2):193-201. PubMed PMID: 17408324
  • Drexler ES, Quinn TP, Slifka AJ, McCowan CN, Bischoff JE, Wright JE, Ivy DD, Shandas R. Comparison of mechanical behavior among the extrapulmonary arteries from rats. J Biomech. 2007;40(4):812-9. PubMed PMID: 16682044
  • Wang R, Lacour-Gayet FG, Lanning CJ, Rech BA, Kilfoil PJ, Hertzberg J, Shandas R. Initial experience with the development and numerical and in vitro studies of a novel low-pressure artificial right ventricle for pediatric Fontan patients. ASAIO J. 2006 Nov-Dec;52(6):682-92. PubMed PMID: 17117059
  • Zheng H, Barker A, Shandas R. Predicting backscatter characteristics from micron- and submicron-scale ultrasound contrast agents using a size-integration technique. IEEE Trans Ultrason Ferroelectr Freq Control. 2006 Mar;53(3):639-44. PubMed PMID: 16555773
  • Orlando W, Shandas R, DeGroff C. Efficiency differences in computational simulations of the total cavo-pulmonary circulation with and without compliant vessel walls. Comput Methods Programs Biomed. 2006 Mar;81(3):220-7. PubMed PMID: 16455152
  • Dyer KL, Pauliks LB, Das B, Shandas R, Ivy D, Shaffer EM, Valdes-Cruz LM. Use of myocardial performance index in pediatric patients with idiopathic pulmonary arterial hypertension. J Am Soc Echocardiogr. 2006 Jan;19(1):21-7. PubMed PMID: 16423665
  • Zheng H, Mukdadi O, Shandas R. Theoretical predictions of harmonic generation from submicron ultrasound contrast agents for nonlinear biomedical ultrasound imaging. Phys Med Biol. 2006 Feb 7;51(3):557-73. PubMed PMID: 16424581
  • Hunter KS, Lanning CJ, Chen SY, Zhang Y, Garg R, Ivy DD, Shandas R. Simulations of congenital septal defect closure and reactivity testing in patient-specific models of the pediatric pulmonary vasculature: A 3D numerical study with fluid-structure interaction. J Biomech Eng. 2006 Aug;128(4):564-72. PubMed PMID: 16813447
  • Dyer K, Lanning C, Das B, Lee PF, Ivy DD, Valdes-Cruz L, Shandas R. Noninvasive Doppler tissue measurement of pulmonary artery compliance in children with pulmonary hypertension. J Am Soc Echocardiogr. 2006 Apr;19(4):403-12. PubMed PMID: 16581479
  • Slifka AJ, Drexler ES, Wright JE, Shandas R. Bubble-test method for synthetic and bovine vascular material. J Biomech. 2006;39(10):1939-42. PubMed PMID: 16085073
  • Gall K, Yakacki CM, Liu Y, Shandas R, Willett N, Anseth KS. Thermomechanics of the shape memory effect in polymers for biomedical applications. J Biomed Mater Res A. 2005 Jun 1;73(3):339-48. PubMed PMID: 15806564
  • DeGroff C, Birnbaum B, Shandas R, Orlando W, Hertzberg J. Computational simulations of the total cavo-pulmonary connection: insights in optimizing numerical solutions. Med Eng Phys. 2005 Mar;27(2):135-46. PubMed PMID: 15642509
  • Mazzaro L, Almasi SJ, Shandas R, Seals DR, Gates PE. Aortic input impedance increases with age in healthy men and women. Hypertension. 2005 Jun;45(6):1101-6. PubMed PMID: 15867143
  • Zheng H, Mukdadi O, Kim H, Hertzberg JR, Shandas R. Advantages in using multifrequency excitation of contrast microbubbles for enhancing echo particle image velocimetry techniques: initial numerical studies using rectangular and triangular waves. Ultrasound Med Biol. 2005 Jan;31(1):99-108. PubMed PMID: 15653236
  • Zhang Y, Dunn ML, Drexler ES, McCowan CN, Slifka AJ, Ivy DD, Shandas R. A microstructural hyperelastic model of pulmonary arteries under normo- and hypertensive conditions. Ann Biomed Eng. 2005 Aug;33(8):1042-52. PubMed PMID: 16133913
  • Weinberg CE, Hertzberg JR, Ivy DD, Kirby KS, Chan KC, Valdes-Cruz L, Shandas R. Extraction of pulmonary vascular compliance, pulmonary vascular resistance, and right ventricular work from single-pressure and Doppler flow measurements in children with pulmonary hypertension: a new method for evaluating reactivity: in vitro and clinical studies. Circulation. 2004 Oct 26;110(17):2609-17. PubMed PMID: 15492299
  • Cooke J, Hertzberg J, Boardman M, Shandas R. Characterizing vortex ring behavior during ventricular filling with Doppler echocardiography: an in vitro study. Ann Biomed Eng. 2004 Feb;32(2):245-56. PubMed PMID: 15008372
  • Kim HB, Hertzberg J, Lanning C, Shandas R. Noninvasive measurement of steady and pulsating velocity profiles and shear rates in arteries using echo PIV: in vitro validation studies. Ann Biomed Eng. 2004 Aug;32(8):1067-76. PubMed PMID: 15446503
  • Mukdadi OM, Kim HB, Hertzberg J, Shandas R. Numerical modeling of microbubble backscatter to optimize ultrasound particle image velocimetry imaging: initial studies. Ultrasonics. 2004 Aug;42(10):1111-21. PubMed PMID: 15234173
  • Zheng H, Mukdadi O, Hertzberg J, Shandas R. Advantages in using multi-frequency driving ultrasound for optimizing echo particle image velocimetry techniques. Biomed Sci Instrum. 2004;40:371-6. PubMed PMID: 15133986
  • Mukdadi O, Shandas R. Ultrasound wave propagation in tissue and scattering from microbubbles for echo particle image velocimetry technique. Biomed Sci Instrum. 2004;40:364-70. PubMed PMID: 15133985
  • Kim HB, Hertzberg JR, Shandas R. Echo PIV for flow field measurements in vivo. Biomed Sci Instrum. 2004;40:357-63. PubMed PMID: 15133984
  • Drost T, Zimmer T, Kim HB, Shandas R, Hertzberg J. Study of in vitro mitral valve filling flow. Biomed Sci Instrum. 2004;40:350-6. PubMed PMID: 15133983
  • Yue X, Hwang FN, Shandas R, Cai XC. Simulation of branching blood flows on parallel computers. Biomed Sci Instrum. 2004;40:325-30. PubMed PMID: 15133979
  • Wright JE, Drexler ES, Slifka AJ, McCowan CN, Ivy DD, Shandas R. Stress and strain in rat pulmonary artery material during a biaxial bubble test. Biomed Sci Instrum. 2004;40:303-8. PubMed PMID: 15133975
  • Drexler ES, McCowan CN, Wright JE, Slifka AJ, Ivy DD, Shandas R. Comparison of strength properties of normotensive and hypertensive rat pulmonary arteries. Biomed Sci Instrum. 2004;40:297-302. PubMed PMID: 15133974
  • Lanning C, Chen SY, Hansgen A, Chang D, Chan KC, Shandas R. Dynamic three-dimensional reconstruction and modeling of cardiovascular anatomy in children with congenital heart disease using biplane angiography. Biomed Sci Instrum. 2004;40:200-5. PubMed PMID: 15133958
  • Liu LL, Mukdadi OM, Hertzberg JR, Shandas R. A model study of capacitive micromachined ultrasonic transducers fabricated using atomic layer deposition process. Biomed Sci Instrum. 2004;40:142-8. PubMed PMID: 15133949
  • Drexler ES, Slifka AJ, Wright JE, McCowan CN, Finch DS, Quinn TP, McColskey JD, Ivy DD, Shandas R. An Experimental Method for Measuring Mechanical Properties of Rat Pulmonary Arteries Verified With Latex. J Res Natl Inst Stand Technol. 2003 May-Jun;108(3):183-91. PubMed PMID: 27413604
  • Khunatorn Y, Shandas R, DeGroff C, Mahalingam S. Comparison of in vitro velocity measurements in a scaled total cavopulmonary connection with computational predictions. Ann Biomed Eng. 2003 Jul-Aug;31(7):810-22. PubMed PMID: 12971614
  • Lanning C, Shandas R. Development and validation of implantable sensors for monitoring function of prosthetic heart valves: in vitro studies. Med Biol Eng Comput. 2003 Jul;41(4):416-24. PubMed PMID: 12892364
  • DeGroff CG, Orlando W, Shandas R. Insights into the effect of aortic compliance on Doppler diastolic flow patterns seen in coarctation of the aorta: a numeric study. J Am Soc Echocardiogr. 2003 Feb;16(2):162-9. PubMed PMID: 12574743
  • Weinberg CE, Hertzberg JR, Shandas R. Use of intravascular ultrasound to measure local compliance of the pediatric pulmonary artery: in vitro studies. J Am Soc Echocardiogr. 2002 Dec;15(12):1507-14. PubMed PMID: 12464920
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Practice Locations

Hospital Affiliation
  • Children's Hospital Colorado
Public Speaking
Yes
Biomedical Engineering; Medical Device Design and Entrepreneurship; Bioengineering Research; Pediatric Cardiovascular Medicine; Advances in Medical Imaging

General Information

Graduate Schools:
  • MSc, University of California, San Diego (1991)
  • PhD, University of California, San Diego (1993)
Undergraduate Schools:
  • BS, University of California System (CA) (1987)
Languages: English
Department: University of Colorado - Denver
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