Christopher Hoyte, MD
Professor, Emergency Medicine

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Medical School:
  • MD, University of Medicine and Dentistry of New Jersey-New Jersey Medical School (2005)
Undergraduate School:
  • AB, Princeton University (NJ) (2000)
Internship:
  • St Joseph Hospital Program (2006)
Residency:
  • Loyola University/Cook County Hospital Program, Emergency Medicine (2009)
Languages: English
Department: Emergency Medicine

Publications

  • Sudanagunta S, Camarena-Michel A, Pennington S, Leonard J, Hoyte C, Wang GS. Comparison of Two-Bag Versus Three-Bag N-Acetylcysteine Regimens for Pediatric Acetaminophen Toxicity. Ann Pharmacother. 2023 Jan;57(1):36-43. PubMed PMID: 35587124
  • Sudanagunta S, Camarena-Michel A, Pennington S, Leonard J, Hoyte C, Wang GS. Comparison of Two-Bag Versus Three-Bag N-Acetylcysteine Regimens for Pediatric Acetaminophen Toxicity. Ann Pharmacother. 2023 Jan;57(1):36-43. PubMed PMID: 35587124
  • Mehrpour O, Hoyte C, Goss F, Shirazi FM, Nakhaee S. Decision tree algorithm can determine the outcome of repeated supratherapeutic ingestion (RSTI) exposure to acetaminophen: review of 4500 national poison data system cases. Drug Chem Toxicol. 2023 Nov;46(4):692-698. PubMed PMID: 35670081
  • Mehrpour O, Saeedi F, Nakhaee S, Tavakkoli Khomeini F, Hadianfar A, Amirabadizadeh A, Hoyte C. Comparison of decision tree with common machine learning models for prediction of biguanide and sulfonylurea poisoning in the United States: an analysis of the National Poison Data System. BMC Med Inform Decis Mak. 2023 Apr 6;23(1):60. PubMed PMID: 37024869
  • Mehrpour O, Hoyte C, Nakhaee S, Megarbane B, Goss F. Using a decision tree algorithm to distinguish between repeated supra-therapeutic and acute acetaminophen exposures. BMC Med Inform Decis Mak. 2023 Jun 1;23(1):102. PubMed PMID: 37264381
  • Mehrpour O, Hoyte C, Al Masud A, Biswas A, Schimmel J, Nakhaee S, Nasr MS, Delva-Clark H, Goss F. Deep learning neural network derivation and testing to distinguish acute poisonings. Expert Opin Drug Metab Toxicol. 2023 Jan-Jun;19(6):367-380. PubMed PMID: 37395108
  • Cohen N, Mathew M, Brent J, Wax P, Davis AL, Obilom C, Burns MM, Canning J, Baumgartner K, Koons AL, Wiegand TJ, Judge B, Hoyte C, Chenoweth JA, Froberg B, Farrar H, Carey JL, Hendrickson RG, Hodgman M, Caravati EM, Christian MR, Wolk BJ, Seifert SA, Bentur Y, Levine M, Farrugia LA, Vearrier D, Minns AB, Kennedy JM, Kirschner RI, Aldy K, Schuh S, Campleman S, Li S, Myran DT, Feng L, Freedman SB, Finkelstein Y. Severe outcomes following pediatric cannabis intoxication: a prospective cohort study of an international toxicology surveillance registry. Clin Toxicol (Phila). 2023 Aug;61(8):591-598. PubMed PMID: 37603042
  • Simon M, Hoyte C. A Case Report of Venezuelan Suntiger Tarantula (Psalmopoeus Irminia) Envenomation and Review of Tarantula Exposures. J Emerg Med. 2023 Sep;65(3):e199-e203. PubMed PMID: 37635034
  • Pepin LC, Simon MW, Banerji S, Leonard J, Hoyte CO, Wang GS. Toxic Tetrahydrocannabinol (THC) Dose in Pediatric Cannabis Edible Ingestions. Pediatrics. 2023 Sep 1;152(3). PubMed PMID: 37635689
  • Lavonas EJ, Akpunonu PD, Arens AM, Babu KM, Cao D, Hoffman RS, Hoyte CO, Mazer-Amirshahi ME, Stolbach A, St-Onge M, Thompson TM, Wang GS, Hoover AV, Drennan IR. 2023 American Heart Association Focused Update on the Management of Patients With Cardiac Arrest or Life-Threatening Toxicity Due to Poisoning: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2023 Oct 17;148(16):e149-e184. PubMed PMID: 37721023
  • Neumann NR, du Plessis A, van Hoving DJ, Hoyte CO, Lermer A, Wittels S, Marks C. Antivenom supply and demand: An analysis of antivenom availability and utilization in South Africa. Afr J Emerg Med. 2023 Dec;13(4):245-249. PubMed PMID: 37745277
  • Mehrpour O, Saeedi F, Vohra V, Hoyte C. Outcome prediction of methadone poisoning in the United States: implications of machine learning in the National Poison Data System (NPDS). Drug Chem Toxicol. 2023 Nov 9;:1-8. [Epub ahead of print] PubMed PMID: 37941394
  • Mehrpour O, Hoyte C, Delva-Clark H, Al Masud A, Biswas A, Schimmel J, Nakhaee S, Goss F. Classification of acute poisoning exposures with machine learning models derived from the National Poison Data System. Basic Clin Pharmacol Toxicol. 2022 Dec;131(6):566-574. PubMed PMID: 36181236
  • Wang GS, Leonard J, Cornell A, Hoyte C. Adolescent US Poison Center Exposure Calls During the COVID-19 Pandemic. J Adolesc Health. 2022 Dec;71(6):764-767. PubMed PMID: 36088226
  • Mehrpour O, Saeedi F, Hoyte C, Goss F, Shirazi FM. Correction: Utility of support vector machine and decision tree to identify the prognosis of metformin poisoning in the United States: analysis of National Poisoning Data System. BMC Pharmacol Toxicol. 2022 Sep 9;23(1):68. PubMed PMID: 36085086
  • Mehrpour O, Saeedi F, Hoyte C, Goss F, Shirazi FM. Utility of support vector machine and decision tree to identify the prognosis of metformin poisoning in the United States: analysis of National Poisoning Data System. BMC Pharmacol Toxicol. 2022 Jul 13;23(1):49. PubMed PMID: 35831909
  • Mehrpour O, Hoyte C, Goss F, Shirazi FM, Nakhaee S. Decision tree algorithm can determine the outcome of repeated supratherapeutic ingestion (RSTI) exposure to acetaminophen: review of 4500 national poison data system cases. Drug Chem Toxicol. 2022 Jun 7;:1-7. [Epub ahead of print] PubMed PMID: 35670081
  • Mehrpour O, Saeedi F, Hoyte C, Hadianfar A, Nakhaee S, Brent J. Distinguishing characteristics of exposure to biguanide and sulfonylurea anti-diabetic medications in the United States. Am J Emerg Med. 2022 Jun;56:171-177. PubMed PMID: 35398707
  • Cohen N, Mathew M, Davis A, Brent J, Wax P, Schuh S, Freedman SB, Froberg B, Schwarz E, Canning J, Tortora L, Hoyte C, Koons AL, Burns MM, McFalls J, Wiegand TJ, Hendrickson RG, Judge B, Quang LS, Hodgman M, Chenoweth JA, Algren DA, Carey J, Caravati EM, Akpunonu P, Geib AJ, Seifert SA, Kazzi Z, Othong R, Greene SC, Holstege C, Tweet MS, Vearrier D, Pizon AF, Campleman SL, Li S, Aldy K, Finkelstein Y. Predictors of severe outcome following opioid intoxication in children. Clin Toxicol (Phila). 2022 Jun;60(6):702-707. PubMed PMID: 35333145
  • Spyres MB, Padilla GK, Gerkin RD, Hoyte CO, Wolk BJ, Ruha AM. Late hemotoxicity following North American rattlesnake envenomation treated with crotalidae immune F(ab')(2) (equine) antivenom and crotalidae immune polyvalent Fab (ovine) antivenom reported to the North American Snakebite Sub-registry. Clin Toxicol (Phila). 2022 Jul;60(7):838-842. PubMed PMID: 35261320
  • Mehrpour O, Saeedi F, Hoyte C. Decision tree outcome prediction of acute acetaminophen exposure in the United States: A study of 30,000 cases from the National Poison Data System. Basic Clin Pharmacol Toxicol. 2022 Jan;130(1):191-199. PubMed PMID: 34649297
  • Glatstein M, Lerman L, Gatt D, Scolnik D, Rimon A, Hoyte C, Iazar I. Echis coloratus envenomation in children: a retrospective case series. Clin Toxicol (Phila). 2022 Mar;60(3):293-297. PubMed PMID: 34319210
  • Amirabadizadeh A, Nakhaee S, Jahani F, Soorgi S, Hoyte CO, Mehrpour O. Prognostic indicators in critically ill poisoned patients: development of a risk-prediction nomogram. Drug Metab Pers Ther. 2020 Sep 28.
  • Glatstein M, Lerman L, Gatt D, Scolnik D, Rimon A, Hoyte C, Iazar I. Echis coloratus envenomation in children: a retrospective case series. Clin Toxicol. 2021 Jul 28;1-5.
  • Spyres MB, Aldy K, Farrugia LA, Kang AM, Love JS, Hoyte C, Campleman SL, Li S, Amaducci A, Schwarz E, Wax PM, Brent J. The Toxicology Investigators Consortium 2020 Annual Report; Toxicology Investigators Consortium Study Group.J Med Toxicol. 2021 Oct;17(4):333-362.
  • Mehrpour O, Saeedi F, Hoyte C. Decision tree outcome prediction of acute acetaminophen exposure in the United States: a study of 30,000 cases from the National Poison Data System. Basic Clin Pharmacol Toxicol. 2021 Oct 14.
  • Hoyte C, Schimmel J, Hadianfar A, Banerji S, Nakhaee S, Mehrpour O. Toxic alcohol poisoning characteristics and treatments from 2000 to 2017 at a United States regional poison center. Daru. 2021 Oct 28.
  • Mehrpour O, Saeedi F, Hadianfar A, Mégarbane B, Hoyte C. Prognostic factors of acetaminophen exposure in the United States: An analysis of 39,000 patients. Hum Exp Toxicol. 2021 Nov 12.
  • Fomepizole as an Adjunct to Acetylcysteine for Acetaminophen Poisoning, American College of Medical Toxicology, Annual Spring Meeting (2021)
  • Impact on Non-Allergic Anaphylactoid Reactions after Implementation of 2-bag Intravenous N-acetylcysteine Regimen for Pediatric Acetaminophen Toxicity, Pediatric Academic Societies (2021)
  • Nakhaee S, Brent J, Hoyte C, Farrokhfall K, Shirazi FM, Askari M, Mehrpour O. The effect of tramadol on blood glucose concentrations: a systematic review. Expert Rev Clin Pharmacol. 2020 May 12:1-13.
  • Farkhondeh T, Khan H, Aschner M, Samini F, Pourbagher-Shahri AM, Aramjoo H, Roshanravan B,Hoyte C, Mehrpour O, Samarghandian S. Impact of Cannabis-Based Medicine on Alzheimer's disease by Focusing on the Amyloid ß- Modifications: A Systematic Study. CNS Neurol Disord Drug Targets. 2020 Jul 8.
  • Mehrpour O, Hoyte C, Amirabadizadeh A, Brent J; Toxicology Investigators Consortium (ToxIC). Clinical characteristics and time trends of hospitalized methadone exposures in the United States based on the Toxicology Investigators Consortium (ToxIC) case registry: 2010-2017. BMC Pharmacol Toxicol. 2020 Jul 22;21(1):53.
  • Amirabadizadeh A, Nakhaee S, Jahani F, Soorgi S, Hoyte CO, Mehrpour O. Prognostic indicators in critically ill poisoned patients: development of a risk-prediction nomogram. Drug Metab Pers Ther. 2020 Sep 28.
  • Miguel Glatstein, Amanda Katz, Nicole Taylor, Julieta Werthein, Efrat Zandberg, Christopher Hoyte. Publication outcomes of abstracts presented at 2013 North American Congress of Clinical Toxicology (NACCT) conference. Clin Toxicol (Phila). 2020 Feb 18;1-4.
  • Applications of Machine Learning Within Clinical Toxicology: A Review, American College of Medical Toxicology, Annual Spring Meeting (2020)
  • Serial Bicarbonate Monitoring in Toxic Alcohol Management, North American Congress of Clinical Toxicology (2020)
  • Regional Poison Center (RPC) Post-Marketing Surveillance Pilot Study: Safety and Effectiveness of Antivenom for the Treatment of Crotalid Envenomation, North American Congress of Clinical Toxicology (2020)
  • Adolescent Marijuana Exposures Reported to the Rocky Mountain Poison Center, North American Congress of Clinical Toxicology (2020)
  • Unintentional Pediatric Marijuana Exposures Reported to the Rocky Mountain Poison Center, North American Congress of Clinical Toxicology (2020)
  • Does time to treatment after Crotaline envenomation predict amount of antivenom used to achieve initial control?, North American Congress of Clinical Toxicology (2020)
  • Rosen's Emergency Medicine: Concepts and Clinical Practice; Volumes 1 &2, 10th Edition. Caustics
  • Monte AA, Bronstein AC, Cao DJ, Heard KJ, Hoppe JA, Hoyte CO, Iwanicki JL, Lavonas EJ. An outbreak of exposure to a novel synthetic cannabinoid. N Engl J Med. 2014 Jan 23;370(4):389-90. PubMed PMID: 24450915
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Practice Locations

UCHealth Emergency Care - Anschutz Medical Campus (Hospital-based)
12505 E. 16th Ave
Aurora, CO 80045
720-848-9111

Hospital Affiliation
  • University of Colorado Hospital

Specialty Information

Specialties
  • Emergency Medicine (2009)
Conditions & Treatments
  • Emergency Care

General Information

Medical Schools:
  • MD, University of Medicine and Dentistry of New Jersey-New Jersey Medical School (2005)
Undergraduate Schools:
  • AB, Princeton University (NJ) (2000)
Internships:
  • St Joseph Hospital Program (2006)
Residency Programs:
  • Loyola University/Cook County Hospital Program, Emergency Medicine (2009)
Languages: English
Department: Emergency Medicine
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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