Emeritus Professor of Pediatrics, Pediatric Cardiology and Intensive Care
Recognition & Awards
2019 Distinguished Service Award, American College of Cardiology
(2019)
Chair and Founder, Section of Pediatric and Congenital Cardiac Intensive Care and Mechanical Circulatory Support, European Society of Pediatric and Neonatal Intensive Care (ESPNIC)
(2016)
President and Chair of the Board, Surgeons of Hope Foundation
(2011)
United Nations-affiliated Non-Governmental Organization
Founder and Emeritus Chair, Working Group on Pediatric Cardiac Intensive Care, Association for the European Pediatric and Congenital Cardiology (AEPC)
(2011)
Suma Cum Laude, Universidad de Costa Rica
(1985)
Research Interests
My research interests are focused on the nutrition of the critically-ill pediatric cardiac patient, quality improvement and safety, development of new monitoring strategies and cardiovascular pharmacology.
Teaching
Emeritus Professor of Pediatrics (Pediatric Cardiology and Intensive Care)
(2007)
School of Medicine,
Pediatrics
Publications
Pediatric and Congenital Cardiology, Cardiac Surgery and Cardiac Intensive Care. 2nd Edition. Eduardo da Cruz, Dunbar-David Ivy, James Jaggers, Eds, Springer-Verlag London Ltd, London, 2020. (Editor-In-Chief)
European Society of Paediatric and Neonatal Intensive Care Textbook. 1st Edition. Pierre Tissieres, Joe Brierley, Daniele DeLuca, Eds. Springer-Verlag London Ltd, London, to be published in June 2021.
da Cruz E, Ivy D. Acute Pulmonary Hypertension. In: Textbook of Pediatric and Congenital Cardiology, Cardiac Surgery and Cardiac Intensive Care. .2nd Edition. Eduardo da Cruz, Dunbar-David Ivy, James Jaggers, Eds, Springer-Verlag London Ltd, London, to be published in 2021.
Da Cruz E, Lacour-Gayet F, Truong U. Double Outlet Right Ventricle. In: Textbook of Pediatric and Congenital Cardiology, Cardiac Surgery and Cardiac Intensive Care. .2nd Edition. Eduardo da Cruz, Dunbar-David Ivy, James Jaggers, Eds, Springer-Verlag London Ltd, London, to be published in 2021.
Turmenian H, da Cruz E, Mitchell M. Supravalvar aortic stenosis. In: Textbook of Pediatric and Congenital Cardiology, Cardiac Surgery and Cardiac Intensive Care. .2nd Edition. Eduardo da Cruz, Dunbar-David Ivy, James Jaggers, Eds, Springer-Verlag London Ltd, London, to be published in 2021.
da Cruz E, Browne L, Darst J, Fonseca B, Jaggers J. Takayasu Arteritis. In: Textbook of Pediatric and Congenital Cardiology, Cardiac Surgery and Cardiac Intensive Care.2nd Edition. Eduardo da Cruz, Dunbar-David Ivy, James Jaggers, Eds, Springer-Verlag London Ltd, London, to be published in 2021.
Singh Y, Tissot C, Fraga MV, Yousef N, Cortes RG, Lopez J, Sanchez-de-Toledo J, Brierley J, Colunga JM, Raffaj D, da Cruz E, Durand P, Kenderessy P, Lang HJ, Nishisaki A, Kneyber MC, Tissieres P, Conlon TW and De Luca D. International, evidence-based guidelines on Point of Care Ultrasound (POCUS) for critically ill neonates and children. Crit Care 2020 (in press)
Singh Y, Fraga MV, da Cruz EM, Yousef N, Gonzalez Cortes R, Colunga JM, Raffaj D, Conlon TW, De Luca D, Tissot C. International, evidence-based guidelines on Point of Care Ultrasound (POCUS) for critically ill neonates and children issued by the POCUS Working Group of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC). Crit Care 2020; 24: 65-81.
Singh Y, Urbano J, Brierly J, Cecchetti C, da Cruz EM, Guillén M, Lopez Herce J, di Nardo M, Saxena R, Tibby S, de Boode W, Lemson J. Recommendations for hemodynamic monitoring in the PICU, a consensus statement from the section of cardiovascular dynamics of ESPNIC. Crit Care 2020 (in press)
Nguyen DA, De Mul A, Hoskote A, Cogo P, da Cruz EM, Erickson S, Lasa JJ, Thiagarajan RR, Bembea MM, Karam O, on behalf of PALISI, ESPNIC, ANZICS PSG, and ELSO. Factors Associated with Initiation of Extracorporeal Cardiopulmonary Resuscitation: an International Survey. Crit Care 2020 (in press)
Raghavan VR, da Cruz E, Kaufman J, Osorio Lujan S. International Survey on the Use of Arginine Vasopressin in the Postoperative Management of Single Ventricle Patients. Ped crit Care Med 2020 (in press)
Critical Care of Children with Heart Disease-Basic Medical and Surgical Concepts. 2nd Edition. Ricardo Munoz, Victor Morell, Carol Schmitt, José Pedro da Silva, Eduardo da Cruz, Eds. Springer-Verlag London Ltd, London, 2020. (Co-Editor)
Bautista C, da Cruz E. Ultrasound for ECMO patients. In: Point of Care Ultrasound for Paediatric and Neonatal Critical Care. 1st Edition. Joan Sanchez de Toledo, Peter Rimensberger, Vincent Muehlethaler Eds. Oxford Clinical Imaging Guides series London UK, 2020
Nguyen DA, De Mul A, Hoskote A, Cogo P, da Cruz EM, Erickson S, Lasa JJ, Thiagarajan RR, Bembea MM, Karam O, on behalf of PALISI, ESPNIC, ANZICS PSG, and ELSO. Factors Associated with Initiation of Extracorporeal Cardiopulmonary Resuscitation: an International Survey. World Federation of Pediatric Intensive & Critical Care Societies 2020 Meeting; Virtual Meeting; December 1-4, 2020
Raghavan V, da Cruz E, Kaufman J, Osorio S. international survey on the use of arginine vasopressin in the postoperative management of single ventricle pediatric patients; AEPC 2020 Meeting, Gothenburg, Sweden, May 13 - 16, 2020
Raghavan V, Kaufman J, Osorio S, da Cruz E. A retrospective cohort study on the use of arginine vasopressin in the postoperative management of Hypoplastic Left Heart Syndrome patients; AEPC 2020 Meeting, Gothenburg, Sweden, May 13 - 16, 2020
Raghavan V, da Cruz E, Kaufman J, Osorio S. international survey on the use of arginine vasopressin in the postoperative management of single ventricle pediatric patients; AEPC 2020 Meeting, Gothenburg, Sweden, May 13 - 16, 2020 (ORAL POSTER PRESENTATION).
Raghavan V, Kaufman J, Osorio S, da Cruz E. A retrospective cohort study on the use of arginine vasopressin in the postoperative management of Hypoplastic Left Heart Syndrome patients; AEPC 2020 Meeting, Gothenburg, Sweden, May 13 - 16, 2020 (ORAL PRESENTATION).
Singh Y, Fraga MV, da Cruz EM, Yousef N, Gonzalez Cortes R, Colunga JM, Raffaj D, Conlon TW, De Luca D, Tissot C. International, evidence-based guidelines on Point of Care Ultrasound (POCUS) for critically ill neonates and children issued by the POCUS Working Group of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC). Crit Care 2020; 24: 65-81.
Singh Y, Urbano J, Brierly J, Cecchetti C, da Cruz EM, Guillén M, Lopez Herce J, di Nardo M, Saxena R, Tibby S, de Boode W, Lemson J. Recommendations for hemodynamic monitoring in the PICU, a consensus statement from the section of cardiovascular dynamics of ESPNIC. Crit Care 2020; 24: 620-633.
Cardiac Intensive care of the Adult with Congenital Heart Disease. 1st Edition. Eduardo da Cruz, Duncan Macrae, Gary Webb Eds, Springer-Verlag London Ltd, London, 2019. (Editor-In-Chief)
Nakano da Cruz E, S Tissot C, Miyamoto S. Cardiac failure. In: Critical Care of Children with Heart Disease-Basic Medical and Surgical Concepts. 2nd Edition. Ricardo Munoz, Victor Morell, Carol Schmitt, José Pedro da Silva, Eduardo da Cruz Eds. Springer-Verlag London Ltd, London, 2019
Truong U, Jaggers J, da Cruz E, Double Outlet Right Ventricle. In: Critical Care of Children with Heart Disease-Basic Medical and Surgical Concepts. 2nd Edition. Ricardo Munoz, Victor Morell, Carol Schmitt, José Pedro da Silva, Eduardo da Cruz Eds. Springer-Verlag London Ltd, London, 2019
Tissot C, da Cruz E, Buckvold S, Myers P. Mitral valve anomalies and related disorders. In: Critical Care of Children with Heart Disease-Basic Medical and Surgical Concepts. 2nd Edition. Ricardo Munoz, Victor Morell, Carol Schmitt, José Pedro da Silva, Eduardo da Cruz Eds. Springer-Verlag London Ltd, London, 2019
Tissot C, Phelps C, da Cruz E, Miyamoto S. Pericardial diseases. In: Critical Care of Children with Heart Disease-Basic Medical and Surgical Concepts. 2nd Edition. Ricardo Munoz, Victor Morell, Carol Schmitt, José Pedro da Silva, Eduardo da Cruz Eds. Springer-Verlag London Ltd, London, 2019
da Cruz E, Ivy D. Acute Pulmonary Hypertension. In: Critical Care of Children with Heart Disease-Basic Medical and Surgical Concepts. 2nd Edition. Ricardo Munoz, Victor Morell, Carol Schmitt, José Pedro da Silva, Eduardo da Cruz Eds. Springer-Verlag London Ltd, London, 2019
Fonseca B, da Cruz E, Jaggers J. Anomalous Coronary Arteries. In: Critical Care of Children with Heart Disease-Basic Medical and Surgical Concepts. 2nd Edition. Ricardo Munoz, Victor Morell, Carol Schmitt, José Pedro da Silva, Eduardo da Cruz Eds. Springer-Verlag London Ltd, London, 2019
da Cruz E, Morell V. Truncus Arteriosus. In: Critical Care of Children with Heart Disease-Basic Medical and Surgical Concepts. 2nd Edition. Ricardo Munoz, Victor Morell, Carol Schmitt, José Pedro da Silva, Eduardo da Cruz Eds. Springer-Verlag London Ltd, London, 2019
da Cruz E, Kaufman J, Fonseca B, Jaggers J. Single ventricle: general aspects. In: Critical Care of Children with Heart Disease-Basic Medical and Surgical Concepts. 2nd Edition. Ricardo Munoz, Victor Morell, Carol Schmitt, José Pedro da Silva, Eduardo da Cruz Eds. Springer-Verlag London Ltd, London, 2019
Kaufman J, Jaggers J, da Cruz E. Atrioventricular Septal Defects. In: Critical Care of Children with Heart Disease-Basic Medical and Surgical Concepts. 2nd Edition. Ricardo Munoz, Victor Morell, Carol Schmitt, José Pedro da Silva, Eduardo da Cruz Eds. Springer-Verlag London Ltd, London, 2019
da Cruz E, Kozik D. Atrial Septal Defects. In: Critical Care of Children with Heart Disease-Basic Medical and Surgical Concepts. 2nd Edition. Ricardo Munoz, Victor Morell, Carol Schmitt, José Pedro da Silva, Eduardo da Cruz Eds. Springer-Verlag London Ltd, London, 2019
Kozik D, Kaufman J, da Cruz E. Patent Ductus Arteriosus. In: Critical Care of Children with Heart Disease-Basic Medical and Surgical Concepts. 2nd Edition. Ricardo Munoz, Victor Morell, Carol Schmitt, José Pedro da Silva, Eduardo da Cruz Eds. Springer-Verlag London Ltd, London, 2019
Tissot C, Younoszai AK, Singh Y, da Cruz E. Echocardiography. In: Critical Care of Children with Heart Disease-Basic Medical and Surgical Concepts. 2nd Edition. Ricardo Munoz, Victor Morell, Carol Schmitt, José Pedro da Silva, Eduardo da Cruz Eds. Springer-Verlag London Ltd, London, 2019
da Cruz E. Conversation with a Leader in Pediatric Cardiac Intensive Care.PCICS Podcast, episode 27. July 2019
Kim JS, Kaufman J, Patel SS, Manco-Johnson M, Di Paola J, da Cruz EM. Antiplatelet Effect of Ketorolac in Children After Congenital Cardiac Surgery. World J Pediatr Congenit Heart Surg. 2018 Nov;9(6):651-658. PubMed PMID: 30322371
Goot BH, Kaufman J, Pan Z, Bourne DWA, Hickey F, Twite M, Galinkin J, Christians U, Zuk J, da Cruz EM. Morphine Pharmacokinetics in Children With Down Syndrome Following Cardiac Surgery. Pediatr Crit Care Med. 2018 May;19(5):459-467. PubMed PMID: 29547456
Kaufman J, da Cruz EM. Perspective Regarding Postoperative Care Following Pediatric Heart Surgery. World J Pediatr Congenit Heart Surg. 2018 Jul;9(4):478. PubMed PMID: 29945515
Bautista-Rodriguez C, Sanchez-de-Toledo J, Da Cruz EM. The Role of Echocardiography in Neonates and Pediatric Patients on Extracorporeal Membrane Oxygenation. Front Pediatr. 2018;6:297. PubMed PMID: 30416991
Tume LN, Balmaks R, da Cruz E, Latten L, Verbruggen S, Valla FV. Enteral Feeding Practices in Infants With Congenital Heart Disease Across European PICUs: A European Society of Pediatric and Neonatal Intensive Care Survey. Pediatr Crit Care Med. 2018 Feb;19(2):137-144. PubMed PMID: 29206731
Kaufman J, Phadke D, Tong S, Eshelman J, Newman S, Ruzas C, da Cruz EM, Osorio S. Clinical Associations of Early Dysnatremias in Critically Ill Neonates and Infants Undergoing Cardiac Surgery. Pediatr Cardiol. 2017 Jan;38(1):149-154. PubMed PMID: 27826706
Sarris GE, Balmer C, Bonou P, Comas JV, da Cruz E, Di Chiara L, Di Donato RM, Fragata J, Jokinen TE, Kirvassilis G, Lytrivi I, Milojevic M, Sharland G, Siepe M, Stein J, Büchel EV, Vouhé PR. Clinical guidelines for the management of patients with transposition of the great arteries with intact ventricular septum. Cardiol Young. 2017 Apr;27(3):530-569. PubMed PMID: 28249633
Gist KM, Kaufman J, da Cruz EM, Friesen RH, Crumback SL, Linders M, Edelstein C, Altmann C, Palmer C, Jalal D, Faubel S. A Decline in Intraoperative Renal Near-Infrared Spectroscopy Is Associated With Adverse Outcomes in Children Following Cardiac Surgery. Pediatr Crit Care Med. 2016 Apr;17(4):342-9. PubMed PMID: 26914625
da Cruz EM, Tabbutt S, Eisenhaur MC, Jacobs JP, Graham EM, Smith LC, Simsic J, Laussen PC. Confessions of PCICU Leaders: Tales From the Past, Lessons for the Future. World J Pediatr Congenit Heart Surg. 2015 Oct;6(4):556-64. PubMed PMID: 26467870
Kaufman J, Vichayavilas P, Rannie M, Peyton C, Carpenter E, Hull D, Alpern J, Barrett C, da Cruz EM, Roosevelt G. Improved nutrition delivery and nutrition status in critically ill children with heart disease. Pediatrics. 2015 Mar;135(3):e717-25. PubMed PMID: 25687139
Jone PN, Mitchell MB, Campbell DN, da Cruz EM. Prenatal diagnosis and successful outcome in neonate of aorto-left ventricle tunnel. Echocardiography. 2014 Jan;31(1):E20-3. PubMed PMID: 24383948
McFerson MC, McCanta AC, Pan Z, Collins KK, Jaggers J, da Cruz EM, Kaufman J. Tachyarrhythmias after the Norwood procedure: relationship and effect of vasoactive agents. Pediatr Cardiol. 2014 Apr;35(4):668-75. PubMed PMID: 24240783
Hauck A, da Cruz EM, Jaggers J, Jone PN. Tricuspid Atresia Associated with Truncus Arteriosus versus Aortopulmonary Window: Combining Fetal and Postnatal Echocardiography to Make the Diagnosis. Echocardiography. 2013 Sep 4. [Epub ahead of print] PubMed PMID: 24033694
Singhal NR, Da Cruz EM, Nicolarsen J, Schwartz LI, Merritt GR, Barrett C, Twite MD, Ing RJ. Perioperative management of shock in two fontan patients with plastic bronchitis. Semin Cardiothorac Vasc Anesth. 2013 Mar;17(1):55-60. PubMed PMID: 23381614
Erwin N, Zuk J, Kaufman J, Pan Z, Carpenter E, Mitchell MB, da Cruz EM. Extended survival and re-hospitalisation among paediatric patients requiring extracorporeal membrane oxygenation for primary cardiac dysfunction. Cardiol Young. 2013;23(2):258-64. PubMed PMID: 22694830
Davidson J, Tong S, Hauck A, Lawson DS, da Cruz E, Kaufman J. Kinetics of procalcitonin and C-reactive protein and the relationship to postoperative infection in young infants undergoing cardiovascular surgery. Pediatr Res. 2013 Oct;74(4):413-9. PubMed PMID: 23863853
Kaufmnan J, Twite M, Barrett C, Peyton C, Koehler J, Rannie M, Kahn MG, Schofield S, Ing RJ, Jaggers J, Hyman D, da Cruz EM. A handoff protocol from the cardiovascular operating room to cardiac ICU is associated with improvements in care beyond the immediate postoperative period. Jt Comm J Qual Patient Saf. 2013 Jul;39(7):306-11. PubMed PMID: 23888640
Kaufman J, Rannie M, Kahn MG, Vitaska M, Wathen B, Peyton C, Judd J, Quinby Z, da Cruz EM, Dobyns E. An interdisciplinary initiative to reduce unplanned extubations in pediatric critical care units. Pediatrics. 2012 Jun;129(6):e1594-600. PubMed PMID: 22585764
Stoica S, Carpenter E, Campbell D, Mitchell M, da Cruz E, Ivy D, Lacour-Gayet F. Morbidity of the arterial switch operation. Ann Thorac Surg. 2012 Jun;93(6):1977-83. PubMed PMID: 22365263
Davidson J, Tong S, Hancock H, Hauck A, da Cruz E, Kaufman J. Prospective validation of the vasoactive-inotropic score and correlation to short-term outcomes in neonates and infants after cardiothoracic surgery. Intensive Care Med. 2012 Jul;38(7):1184-90. PubMed PMID: 22527067
Dumond AA, da Cruz E, Almodovar MC, Friesen RH. Femoral artery catheterization in neonates and infants. Pediatr Crit Care Med. 2012 Jan;13(1):39-41. PubMed PMID: 21478789
Sables-Baus S, Kaufman J, Cook P, da Cruz EM. Oral feeding outcomes in neonates with congenital cardiac disease undergoing cardiac surgery. Cardiol Young. 2012 Feb;22(1):42-8. PubMed PMID: 21729496
Howley LW, Kaufman J, Wymore E, Thureen P, Magouirk JK, McNair B, da Cruz EM. Enteral feeding in neonates with prostaglandin-dependent congenital cardiac disease: international survey on current trends and variations in practice. Cardiol Young. 2012 Apr;22(2):121-7. PubMed PMID: 21771388
Clarke M, da Cruz E, Koehler J, Kaufman J. A multicenter survey of heparin prophylaxis practice in pediatric critical care. J Intensive Care Med. 2011 Sep-Oct;26(5):314-7. PubMed PMID: 21436172
Burton GL, Kaufman J, Goot BH, da Cruz EM. The use of Arginine Vasopressin in neonates following the Norwood procedure. Cardiol Young. 2011 Oct;21(5):536-44. PubMed PMID: 21554826
Teng SN, Kaufman J, Czaja AS, Friesen RH, da Cruz EM. Propofol as a bridge to extubation for high-risk children with congenital cardiac disease. Cardiol Young. 2011 Feb;21(1):46-51. PubMed PMID: 20955640
da Cruz E, Lechner E, Stiller B, Munoz R, Beghetti M, Fakler U, Haas N. Recommendations from the Association for European Paediatric Cardiology for training in paediatric cardiac intensive care. Cardiol Young. 2011 Aug;21(4):480-4. PubMed PMID: 21672292
Teng S, Kaufman J, Pan Z, Czaja A, Shockley H, da Cruz E. Continuous arterial pressure waveform monitoring in pediatric cardiac transplant, cardiomyopathy and pulmonary hypertension patients. Intensive Care Med. 2011 Aug;37(8):1297-301. PubMed PMID: 21626432
Caverly L, Rausch CM, da Cruz E, Kaufman J. Octreotide treatment of chylothorax in pediatric patients following cardiothoracic surgery. Congenit Heart Dis. 2010 Nov-Dec;5(6):573-8. PubMed PMID: 21106017
Tissot C, Buchholz H, Mitchell MB, da Cruz E, Miyamoto SD, Pietra BA, Charpentier A, Ghez O. First pediatric transatlantic air ambulance transportation on a Berlin Heart EXCOR left ventricular assist device as a bridge to transplantation. Pediatr Crit Care Med. 2010 Mar;11(2):e24-5. PubMed PMID: 20216173
King DS, da Cruz E, Kaufman J. A model for a nurse-led programme of bedside placement of peripherally inserted central catheters in neonates and infants with congenital cardiac disease. Cardiol Young. 2010 Jun;20(3):302-7. PubMed PMID: 20346200
Cavanaugh JL, Miyamoto SD, da Cruz E, Pietra BA, Campbell DN, Mitchell MB, Peyton CE, Gruenwald J, Darst JR. Predicting recovery: successful explant of a ventricular assist device in a child with dilated cardiomyopathy. J Heart Lung Transplant. 2010 Jan;29(1):105-8. PubMed PMID: 19783171
Phelps CM, Da Cruz E, Fagan T, Younoszai AK, Tissot C. Images in cardiovascular medicine. Anterior origin of the main pulmonary artery from the arterial valvar sinus: unusual truncus arteriosus. Circulation. 2009 Feb 3;119(4):624-7. PubMed PMID: 19188523
Karam O, da Cruz E, Rimensberger PC. VGAM induced high-flow congestive heart failure responsive to PGE1 infusion. Int J Cardiol. 2009 Feb 20;132(2):e60-2. PubMed PMID: 18022260
Goldberg SP, McCanta AC, Campbell DN, Carpenter EV, Clarke DR, da Cruz E, Ivy DD, Lacour-Gayet FG. Implications of incising the ventricular septum in double outlet right ventricle and in the Ross-Konno operation. Eur J Cardiothorac Surg. 2009 Apr;35(4):589-93; discussion 593. PubMed PMID: 19269838
da Cruz EM, Beghetti M, Kalangos A, Berner M, Sierra J, Aggoun Y, Tissot C, Pellegrini M, Saudan S, Habre W, Rimensberger PC. Mechanical support availability in pediatric cardiac surgery: program size should not matter. Int J Cardiol. 2008 Sep 26;129(2):282-4. PubMed PMID: 17689727
Tissot C, Corbelli R, Aggoun Y, Beghetti M, da Cruz E. Bronchoscopic diagnosis of asymptomatic unilateral pulmonary vein atresia in an infant. Pediatr Cardiol. 2008 Sep;29(5):976-9. PubMed PMID: 18026778
Tissot C, Darst JR, Kaza AK, Younoszai AK, da Cruz E. Partial left pulmonary artery sling associated with multiple ventricular septal defects: a rare congenital anomaly. J Thorac Cardiovasc Surg. 2008 Oct;136(4):1085-7. PubMed PMID: 18954657
Tissières P, da Cruz E, Habre W, Aggoun Y, Mensi N, Kalangos A, Beghetti M. Value of brain natriuretic peptide in the perioperative follow-up of children with valvular disease. Intensive Care Med. 2008 Jun;34(6):1109-13. PubMed PMID: 18283430
Willis L, Thureen P, Kaufman J, Wymore E, Skillman H, da Cruz E. Enteral feeding in prostaglandin-dependent neonates: is it a safe practice?. J Pediatr. 2008 Dec;153(6):867-9. PubMed PMID: 19014824
Tissot C, Rimensberger PC, Aggoun Y, Kalangos A, Ozsahin H, Beghetti M, da Cruz EM. Tissue plasminogen activator for a left atrial thrombus after Senning repair. Pediatr Crit Care Med. 2007 May;8(3):279-81. PubMed PMID: 17417122
Tissot C, da Cruz E, Beghetti M, Aggoun Y. Successful use of a new Amplatzer Vascular plug for percutaneous closure of a large aortopulmonary collateral artery in a pulmonary atresia with ventricular septal defect prior to complete repair. Int J Cardiol. 2007 Mar 20;116(2):e39-41. PubMed PMID: 17052781
Tissot C, Aggoun Y, Rimensberger PC, Sierra J, Kalangos A, Beghetti M, da Cruz E. Left ventricular epicardial VVI pacing for a congenital complete heart block with severe myocardial dysfunction: shall epicardial pacing wires be positioned left?. Int J Cardiol. 2007 Mar 2;116(1):e7-9. PubMed PMID: 17049639
Tissot C, Pache JC, da Cruz E. Clinical vignette. A giant congenital left ventricular diverticulum simulating an aneurysm. Eur Heart J. 2007 Jan;28(1):25. PubMed PMID: 16772341
Tissot C, da Cruz E, Aggoun Y. Rescue left main coronary artery stenting for acute myocardial ischemia after coronary angiography in a 7-year-old girl with homozygous familial hypercholesterolemia. Catheter Cardiovasc Interv. 2007 Feb 1;69(2):243-7. PubMed PMID: 17191220
Tissot C, Aggoun Y, Beghetti M, da Cruz E, Sierra J, Kalangos A. The Lecompte maneuver as an alternative to reduction pulmonary arterioplasty for relief of airway compression in absent pulmonary valve syndrome. Ann Thorac Surg. 2007 Feb;83(2):727; author reply 727-8. PubMed PMID: 17258038
da Cruz E, Aggoun Y, Tissot C, Beghetti M. Re: Systematic placement of left-sided pacing leads as an appealing option for cardiac resynchronization as treatment of congestive cardiac failure in children dependent on chronic cardiac pacing. Cardiol Young. 2007 Apr;17(2):234-5. PubMed PMID: 17291395
da Cruz E, Billieux MH, Beghetti M. A neonate with isolated combined aortic and pulmonary valvar stenosis. Int J Cardiol. 2007 Mar 2;116(1):e13-4. PubMed PMID: 17095108
Motti A, Tissot C, Rimensberger PC, Prina-Rousso A, Aggoun Y, Berner M, Beghetti M, da Cruz E. Intravenous adenosine for refractory pulmonary hypertension in a low-weight premature newborn: a potential new drug for rescue therapy. Pediatr Crit Care Med. 2006 Jul;7(4):380-2. PubMed PMID: 16738499
da Cruz E, Aggoun Y, Tissot-Daguette C, Beghetti M. Fatal coronary artery anomaly presenting as bronchiolitis. Eur J Pediatr. 2006 Jul;165(7):505; author reply 506. PubMed PMID: 16602012
Beghetti M, Aggoun Y, Da Cruz E. Nitric oxide precursors and congenital cardiac surgery: a randomized controlled trial of oral citrulline. Definition of pulmonary hypertension in Fontan circulation?. J Thorac Cardiovasc Surg. 2006 Dec;132(6):1501-2. PubMed PMID: 17141000
Tissières P, Aggoun Y, Da Cruz E, Sierra J, Mensi N, Kalangos A, Beghetti M. Comparison of classifications for heart failure in children undergoing valvular surgery. J Pediatr. 2006 Aug;149(2):210-5. PubMed PMID: 16887436
da Cruz E, Carbognani D. A "friendly" system for pericardial drainage. Cardiol Young. 2000 Jan;10(1):52-3. PubMed PMID: 10695542
da Cruz E. Anomalous left coronary artery arising from the right pulmonary artery. Cardiol Young. 1999 Jan;9(1):109. PubMed PMID: 10323554
Da Cruz E, Milella L, Corno A. Left isomerism with tetralogy of Fallot and anomalous systemic and pulmonary venous connections. Cardiol Young. 1998 Jan;8(1):131-3. PubMed PMID: 9680287
da Cruz E, Carbognani D, Laborde F, Bougaran J, Dibie A, Le Bidois J, Batisse A, Fermont L. Aortic coarctation, multiple ventricular septal defects, and anomalous coronary artery arising from the right pulmonary artery. J Thorac Cardiovasc Surg. 1998 Jan;115(1):244-6. PubMed PMID: 9451072
Laborde F, Folliguet T, Da Cruz E, Batisse A, Carbognani D, Dibie A. Video surgical technique for interruption of patent ductus arteriosus in children and neonates. Pediatr Pulmonol Suppl. 1997;16:177-9. PubMed PMID: 9443261
Laborde F, Folliguet T, Batisse A, Dibie A, da Cruz E, Carbognani D. [Closure of patent ductus arteriosus by video thoracoscopy in 282 children]. Arch Mal Coeur Vaiss. 1996 May;89(5):547-51. PubMed PMID: 8758562
Laborde F, Folliguet T, Batisse A, Dibie A, da-Cruz E, Carbognani D. Video-assisted thoracoscopic surgical interruption: the technique of choice for patent ductus arteriosus. Routine experience in 230 pediatric cases. J Thorac Cardiovasc Surg. 1995 Dec;110(6):1681-4; discussion 1684-5. PubMed PMID: 8523880
Leca F, Karam J, Vouhe PR, Khoury W, Tamisier D, Bical O, Da Cruz E, Thibert M. Surgical treatment of multiple ventricular septal defects using a biologic glue. J Thorac Cardiovasc Surg. 1994 Jan;107(1):96-102. PubMed PMID: 8283925
Acar P, Sidi D, Kachaner J, Gournay V, Iserin L, Da Cruz E, Delogu A. [Cavopulmonary shunts in the treatment of univentricular heart diseases in children. An experience of 60 cases]. Arch Mal Coeur Vaiss. 1993 May;86(5):601-7. PubMed PMID: 8257270
Piéchaud JF, Ladeia AM, Da Cruz E, Gournay V, Iserin L, Delogu A, Cohen L, Sidi D, Kachaner J. [Perforation-dilatation of pulmonary atresia with intact interventricular septum in neonates and infants]. Arch Mal Coeur Vaiss. 1993 May;86(5):581-6. PubMed PMID: 8257267
Sidi D, Le Bidois J, Piéchaud JF, Da Cruz E, Marchal C, Gournay V, Kachaner J, Rustin P, Chrétien D, Munnich A. [Enzymatic activities of the mitochondrial respiratory chain in child cardiomyopathies. 34 cases prospectively studied by endomyocardial biopsy]. Arch Mal Coeur Vaiss. 1992 May;85(5):541-6. PubMed PMID: 1530392
Villain E, Bonnet D, Attali T, Da Cruz E, Marchal C, Gournay V, Kachaner J. [Rhythmogenic cardiomyopathies of atrial origin in children. Myth or reality?]. Arch Mal Coeur Vaiss. 1992 May;85(5):547-51. PubMed PMID: 1356326
Benamer H, Sluysmans T, Sidi D, Marchal C, Da Cruz E, Le Bidois J, Piéchaud JF, Bianca I, Kachaner J. [Right pulmonary artery arising from the proximal ascending aorta. A model of reflex pulmonary hypertension of the left lung?]. Arch Mal Coeur Vaiss. 1991 May;84(5):639-46. PubMed PMID: 1898198
Villain E, Marchal C, Levy M, Da Cruz E, Marçon F, Worms AM, Kachaner J. [Congenital long QT syndrome. Mid-term prognosis]. Arch Mal Coeur Vaiss. 1991 May;84(5):653-8. PubMed PMID: 1680318
Nguyen DA, De Mul A, Hoskote A, Cogo P, da Cruz EM, Erickson S, Lasa JJ, Thiagarajan RR, Bembea MM, Karam O, on behalf of PALISI, ESPNIC, ANZICS PSG, and ELSO. Factors Associated with Initiation of Extracorporeal Cardiopulmonary Resuscitation: an International Survey. ASAIO 2021 (Online ahead of print)
Raghavan VR, da Cruz E, Kaufman J, Osorio Lujan S. International Survey on the Use of Arginine Vasopressin in the Postoperative Management of Single Ventricle Patients. Frontiers Ped 2021 (Epub ahead of print)
Association for the European Pediatric Cardiology, Member; Emeritus Founder Cardiac Critical care Working Group
European Association for Cardiothoracic Surgery, Member, Board of the Congenital Domain
European Society of Pediatric and Neonatal Intensive Care, Member; Founder and Past-Chair Section of Cardiac Critical Care and Mechanical Circulatory Support
European Society of Intensive Care Medicine, Member
Society of Critical Care Medicine, Member
Swiss Society of Pediatric Cardiology, Member
Societe Francaise de Cardiologie, Member
Pediatric Cardiac Intensive Care Society, Member
European Society of Cardiology, Member
Society For Pediatric Research (SPR), Member
Sociedad Latina de Cardiologia y Cirugia Cardiovascular, Member
World Society for Pediatric and Congenital Heart Surgery, Member
World federation of Pediatric Intensive and Critical Care Societies, Member
Pediatric Intensive Care Society of the United Kingdom, Member
British Pediatric Cardiac Association, Member
STS, Member
American College of Cardiology, Member, FACC (Fellow)
Specialty Information
Specialties
Pediatric Cardiology (1992)
Pediatrics, Board Certification (1989)
Pediatric Critical Care Medicine (1992)
European Board of Pediatric Cardiology, Certificate
(1994)
Conditions & Treatments
Heart and Circulation - Congenital Heart Disease
Critical Care
Heart and Circulation
Clinical Interests
I trained in Pediatrics, Pediatric Cardiology and Intensive Care, and have 30 years of experience as an attending physician. Over the last three decades I have developed an expertise in the management of medical and surgical (pre and post-operative) cardiac patients, from neonates to adults with congenital cardiac diseases. My main interest is to serve patients and their families and my community to the best of my capacities and thinking beyond the strictly medical aspects, as patient psycho-emotional support and quality of life is key.
Care Philosophy
I strive to promote quality, safety, effectiveness, interdisciplinary practices and optimal communication between patients, their families and our staff. Our care must be patient and family-centered and driven toward the best outcome possible.
Volunteer Activities
I have been involved in humanitarian work for more than three decades and I am currently the President and Chair of the Board of Surgeons of Hope, a United Nations-affiliated Non-Governmental Organization based in New York and in charge of developing programs of pediatric cardiology and cardiac surgery in Latin America. My ultimate goal in the mid term is to implement and consolidate a Central American Network of Pediatric Cardiac Care.
Public Speaking Yes
General Information
Medical Schools:
MD, Universidad de Costa Rica
(1986)
Fellowships:
University of Paris, Rene Descartes, Pediatric Cardiology & Pediatric Critical Care Medicine
(1992)