Aline Maddux, MD
Assistant Professor, Pediatrics-Critical Care Medicine

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Medical School:
  • MD, Vanderbilt University School of Medicine (2008)
Undergraduate School:
  • BA, Johns Hopkins University (MD) (2004)
Residency:
  • University of Colorado (Children's Hospital Colorado) Program, Chief Resident, Pediatrics (2011)
Languages: English
Department: Pediatrics-Critical Care Medicine

Publications

  • Meert KL, Reeder RW, Maddux AB, Banks R, Berg RA, Newth CJ, Hall MW, Quasney M, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Sorenson S, McGalliard J, Dean JM, Zimmerman JJ. Health-Related Quality of Life After Community-Acquired Septic Shock in Children With Preexisting Severe Developmental Disabilities. Pediatr Crit Care Med. 2020 Nov 6. [Epub ahead of print] PubMed PMID: 33156209
  • O'Keefe S, Maddux AB, Bennett KS, Youngwerth J, Czaja AS. Variation in Pediatric Palliative Care Allocation Among Critically Ill Children in the United States. Pediatr Crit Care Med. 2020 Oct 28. [Epub ahead of print] PubMed PMID: 33116070
  • Fink EL, Maddux AB, Pinto N, Sorenson S, Notterman D, Dean JM, Carcillo JA, Berg RA, Zuppa A, Pollack MM, Meert KL, Hall MW, Sapru A, McQuillen PS, Mourani PM, Wessel D, Amey D, Argent A, Brunow de Carvalho W, Butt W, Choong K, Curley MAQ, Del Pilar Arias Lopez M, Demirkol D, Grosskreuz R, Houtrow AJ, Knoester H, Lee JH, Long D, Manning JC, Morrow B, Sankar J, Slomine BS, Smith M, Olson LM, Watson RS. A Core Outcome Set for Pediatric Critical Care. Crit Care Med. 2020 Dec;48(12):1819-1828. PubMed PMID: 33048905
  • Maddux AB, Pinto N, Fink EL, Hartman ME, Nett S, Biagas K, Killien EY, Dervan LA, Christie LM, Luckett PM, Loftis L, Lackey M, Ringwood M, Smith M, Olson L, Sorenson S, Meert KL, Notterman DA, Pollack MM, Mourani PM, Watson RS. Postdischarge Outcome Domains in Pediatric Critical Care and the Instruments Used to Evaluate Them: A Scoping Review. Crit Care Med. 2020 Dec;48(12):e1313-e1321. PubMed PMID: 33009099
  • Mourani PM, Sontag MK, Williamson KM, Harris JK, Reeder R, Locandro C, Carpenter TC, Maddux AB, Ziegler K, Simões EAF, Osborne CM, Ambroggio L, Leroue MK, Robertson CE, Langelier C, DeRisi JL, Kamm J, Hall MW, Zuppa AF, Carcillo J, Meert K, Sapru A, Pollack MM, McQuillen P, Notterman DA, Dean JM, Wagner BD. Temporal airway microbiome changes related to ventilator associated pneumonia in children. Eur Respir J. 2020 Oct 2. [Epub ahead of print] PubMed PMID: 33008935
  • Meert KL, Reeder R, Maddux AB, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock KB, Dean JM, Zimmerman JJ. Trajectories and Risk Factors for Altered Physical and Psychosocial Health-Related Quality of Life After Pediatric Community-Acquired Septic Shock. Pediatr Crit Care Med. 2020 Oct;21(10):869-878. PubMed PMID: 32667767
  • Feldstein LR, Rose EB, Horwitz SM, Collins JP, Newhams MM, Son MBF, Newburger JW, Kleinman LC, Heidemann SM, Martin AA, Singh AR, Li S, Tarquinio KM, Jaggi P, Oster ME, Zackai SP, Gillen J, Ratner AJ, Walsh RF, Fitzgerald JC, Keenaghan MA, Alharash H, Doymaz S, Clouser KN, Giuliano JS Jr, Gupta A, Parker RM, Maddux AB, Havalad V, Ramsingh S, Bukulmez H, Bradford TT, Smith LS, Tenforde MW, Carroll CL, Riggs BJ, Gertz SJ, Daube A, Lansell A, Coronado Munoz A, Hobbs CV, Marohn KL, Halasa NB, Patel MM, Randolph AG. Multisystem Inflammatory Syndrome in U.S. Children and Adolescents. N Engl J Med. 2020 Jul 23;383(4):334-346. PubMed PMID: 32598831
  • Yehya N, Harhay MO, Klein MJ, Shein SL, Piñeres-Olave BE, Izquierdo L, Sapru A, Emeriaud G, Spinella PC, Flori HR, Dahmer MK, Maddux AB, Lopez-Fernandez YM, Haileselassie B, Hsing DD, Chima RS, Hassinger AB, Valentine SL, Rowan CM, Kneyber MCJ, Smith LS, Khemani RG, Thomas NJ. Predicting Mortality in Children With Pediatric Acute Respiratory Distress Syndrome: A Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology Study. Crit Care Med. 2020 Jun;48(6):e514-e522. PubMed PMID: 32271186
  • Berger JT, Maddux AB, Reeder RW, Banks R, Mourani PM, Berg RA, Carcillo JA, Carpenter T, Hall MW, Meert KL, McQuillen PS, Pollack MM, Sapru A, Yates AR, Notterman DA, Holubkov R, Dean JM, Wessel DL. Inhaled Nitric Oxide Use in Pediatric Hypoxemic Respiratory Failure. Pediatr Crit Care Med. 2020 Aug;21(8):708-719. PubMed PMID: 32195895
  • Fink EL, Jarvis JM, Maddux AB, Pinto N, Galyean P, Olson LM, Zickmund S, Ringwood M, Sorenson S, Dean JM, Carcillo JA, Berg RA, Zuppa A, Pollack MM, Meert KL, Hall MW, Sapru A, McQuillen PS, Mourani PM, Watson RS. Development of a core outcome set for pediatric critical care outcomes research. Contemp Clin Trials. 2020 Apr;91:105968. PubMed PMID: 32147572
  • Rowan CM, Klein MJ, Hsing DD, Dahmer MK, Spinella PC, Emeriaud G, Hassinger AB, Piñeres-Olave BE, Flori HR, Haileselassie B, Lopez-Fernandez YM, Chima RS, Shein SL, Maddux AB, Lillie J, Izquierdo L, Kneyber MCJ, Smith LS, Khemani RG, Thomas NJ, Yehya N. Early Use of Adjunctive Therapies for Pediatric Acute Respiratory Distress Syndrome: A PARDIE Study. Am J Respir Crit Care Med. 2020 Jun 1;201(11):1389-1397. PubMed PMID: 32130867
  • Fink EL, Clark RSB, Panigrahy A, Berger R, Wisnowski J, Bluml S, Maloney D, Rubin P, Haller T, Bayir H, Beers SR, Kochanek PM, Fabio A. Personalising Outcomes after Child Cardiac Arrest (POCCA): design and recruitment challenges of a multicentre, observational study. BMJ Open. 2020 Oct 27;10(10):e039323. PubMed PMID: 33109667
  • Feldstein LR, Self WH, Ferdinands JM, Randolph AG, Aboodi M, Baughman AH, Brown SM, Exline MC, Files DC, Gibbs K, Ginde AA, Gong MN, Grijalva CG, Halasa N, Khan A, Lindsell CJ, Newhams M, Peltan ID, Prekker ME, Rice TW, Shapiro NI, Steingrub J, Talbot HK, Halloran ME, Patel M. Incorporating real-time influenza detection into the test-negative design for estimating influenza vaccine effectiveness: The real-time test-negative design (rtTND). Clin Infect Dis. 2020 Sep 25. [Epub ahead of print] PubMed PMID: 32974644
  • Khemani RG, Smith L, Lopez-Fernandez YM, Kwok J, Morzov R, Klein MJ, Yehya N, Willson D, Kneyber MCJ, Lillie J, Fernandez A, Newth CJL, Jouvet P, Thomas NJ. Paediatric acute respiratory distress syndrome incidence and epidemiology (PARDIE): an international, observational study. Lancet Respir Med. 2019 Feb;7(2):115-128. PubMed PMID: 30361119
  • Maddux AB, Cox-Martin M, Dichiaro M, Bennett TD. The Association Between the Functional Status Scale and the Pediatric Functional Independence Measure in Children Who Survive Traumatic Brain Injury. Pediatr Crit Care Med. 2018 Nov;19(11):1046-1053. PubMed PMID: 30119094
  • Maddux AB, Bennett TD. Mortality After Pediatric Critical Illness: Made It Home, Still Vulnerable. Pediatr Crit Care Med. 2018 Mar;19(3):272-273. PubMed PMID: 29499026
  • Maddux AB, Zimmerman JJ. Awake or Sedate . . . Do We Know the Best State?. Am J Respir Crit Care Med. 2018 Jun 1;197(11):1378-1380. PubMed PMID: 29365272
  • Maddux AB, DeWitt PE, Mourani PM, Bennett TD. Hospital Readmissions After Pediatric Trauma. Pediatr Crit Care Med. 2018 Jan;19(1):e31-e40. PubMed PMID: 29210926
  • Davidson JA, Urban TT, Tong S, Maddux A, Hill G, Frank BS, Watson JD, Jaggers J, Simões EAF, Wischmeyer P. Alkaline Phosphatase Activity and Endotoxemia after Infant Cardiothoracic Surgery. Shock. 2018 Apr 16. [Epub ahead of print] PubMed PMID: 29664834
  • Khemani RG, Smith L, Lopez-Fernandez YM, Kwok J, Morzov R, Klein MJ, Yehya N, Willson D, Kneyber MCJ, Lillie J, Fernandez A, Newth CJL, Jouvet P, Thomas NJ. Paediatric acute respiratory distress syndrome incidence and epidemiology (PARDIE): an international, observational study. Lancet Respir Med. 2018 Oct 22. [Epub ahead of print] PubMed PMID: 30361119
  • Maddux AB, DeWitt PE, Mourani PM, Bennett TD. Hospital Readmissions After Pediatric Trauma. Pediatr Crit Care Med. 2017 Nov 28. [Epub ahead of print] PubMed PMID: 29210926
  • Maddux AB, Hiller TD, Overdier KH, Pyle LL, Douglas IS. Innate Immune Function and Organ Failure Recovery in Adults With Sepsis. J Intensive Care Med. 2017 Jan 1;:885066617701903. [Epub ahead of print] PubMed PMID: 28372498
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Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation
  • Children's Hospital Colorado

Specialty Information

Specialties
  • Pediatrics, Board Certification

General Information

Medical Schools:
  • MD, Vanderbilt University School of Medicine (2008)
Undergraduate Schools:
  • BA, Johns Hopkins University (MD) (2004)
Residency Programs:
  • University of Colorado (Children's Hospital Colorado) Program, Chief Resident, Pediatrics (2011)
Languages: English
Department: Pediatrics-Critical Care Medicine
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