Edwin Asturias, MD
Associate Professor, Pediatrics-Infectious Diseases

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Medical School:
  • MD, University of San Carlos School of Medicine (1989)
Internship:
  • University of Colorado (Children's Hospital Colorado) Program (1993)
Residency:
  • University of Colorado (Children's Hospital Colorado) Program, Pediatrics (1995)
Fellowships:
  • Johns Hopkins University School of Medicine Program, Pediatric Infectious Diseases (1998)
Languages: English, Spanish
Department: Pediatrics-Infectious Diseases

Professional Titles

  • Associate Professor, Pediatrics-Infectious Diseases
  • Director for Latin America

Recognition & Awards

  • Chairholder, The Jules Amer Chair in Community Pediatrics - Children's Hospital Colorado, (2018)
  • Elected Faculty Member, Alpha Upsilon Chapter, Delta Omega Society, (2017)
Research interests for Patients:
Vaccine safety New vaccine global introductions and epidemiology Dengue and Zika infections Pneumococcal disease and prevention

Teaching

  • Associate Professor (2013)
    School of Medicine, Pediatrics

Publications

  • Bandyopadhyay AS, Asturias EJ, O'Ryan M, Oberste MS, Weldon W, Clemens R, Rüttimann R, Modlin JF, Gast C. Exploring the relationship between polio type 2 serum neutralizing antibodies and intestinal immunity using data from two randomized controlled trials of new bOPV-IPV immunization schedules. Vaccine. 2017 Nov 14. [Epub ahead of print] PubMed PMID: 29150209
  • Gaensbauer JT, Melgar MA, Calvimontes DM, Lamb MM, Asturias EJ, Contreras-Roldan IL, Dominguez SR, Robinson CC, Berman S. Efficacy of a bovine colostrum and egg-based intervention in acute childhood diarrhoea in Guatemala: a randomised, double-blind, placebo-controlled trial. BMJ Glob Health. 2017;2(4):e000452. PubMed PMID: 29259822
  • Bosch I, de Puig H, Hiley M, Carré-Camps M, Perdomo-Celis F, Narváez CF, Salgado DM, Senthoor D, O'Grady M, Phillips E, Durbin A, Fandos D, Miyazaki H, Yen CW, Gélvez-Ramírez M, Warke RV, Ribeiro LS, Teixeira MM, Almeida RP, Muñóz-Medina JE, Ludert JE, Nogueira ML, Colombo TE, Terzian ACB, Bozza PT, Calheiros AS, Vieira YR, Barbosa-Lima G, Vizzoni A, Cerbino-Neto J, Bozza FA, Souza TML, Trugilho MRO, de Filippis AMB, de Sequeira PC, Marques ETA, Magalhaes T, Díaz FJ, Restrepo BN, Marín K, Mattar S, Olson D, Asturias EJ, Lucera M, Singla M, Medigeshi GR, de Bosch N, Tam J, Gómez-Márquez J, Clavet C, Villar L, Hamad-Schifferli K, Gehrke L. Rapid antigen tests for dengue virus serotypes and Zika virus in patient serum. Sci Transl Med. 2017 Sep 27;9(409). PubMed PMID: 28954927
  • Wichmann O, Vannice K, Asturias EJ, de Albuquerque Luna EJ, Longini I, Lopez AL, Smith PG, Tissera H, Yoon IK, Hombach J. Live-attenuated tetravalent dengue vaccines: The needs and challenges of post-licensure evaluation of vaccine safety and effectiveness. Vaccine. 2017 Oct 9;35(42):5535-5542. PubMed PMID: 28893477
  • Kamidani S, Melgar M, Robinson C, Asturias E, Berman S, Gaensbauer J. No Detection of Entamoeba histolytica by Multiplex PCR in Children with Acute Non-Bloody Diarrhea in Guatemala. Pediatr Infect Dis J. 2017 Aug 26. [Epub ahead of print] PubMed PMID: 28858041
  • Bandyopadhyay AS, Asturias EJ, O'Ryan M, Oberste MS, Weldon W, Clemens R, Rüttimann R, Modlin JF, Gast C. Exploring the relationship between polio type 2 serum neutralizing antibodies and intestinal immunity using data from two randomized controlled trials of new bOPV-IPV immunization schedules. Vaccine. 2017 Nov 14. [Epub ahead of print] PubMed PMID: 29150209
  • Brown AE, Asturias EJ, Melgar M, Antillon-Klussmann FA, Mettler P, Levin MJ. Incidence and consequences of varicella in children treated for cancer in Guatemala. World J Pediatr. 2016 Aug;12(3):320-6. PubMed PMID: 27351567
  • Wright PF, Connor RI, Wieland-Alter WF, Hoen AG, Boesch AW, Ackerman ME, Oberste MS, Gast C, Brickley EB, Asturias EJ, Rüttimann R, Bandyopadhyay AS. Vaccine-induced mucosal immunity to poliovirus: analysis of cohorts from an open-label, randomised controlled trial in Latin American infants. Lancet Infect Dis. 2016 Sep 13. [Epub ahead of print] PubMed PMID: 27638357
  • Dutmer CM, Asturias EJ, Smith C, Dishop MK, Schmid DS, Bellini WJ, Tirosh I, Lee YN, Notarangelo LD, Gelfand EW. Late Onset Hypomorphic RAG2 Deficiency Presentation with Fatal Vaccine-Strain VZV Infection. J Clin Immunol. 2015 Oct 29. [Epub ahead of print] PubMed PMID: 26515615
  • Smith C, Dutmer C, Schmid DS, Dishop MK, Bellini WJ, Gelfand EW, Asturias EJ. A Toddler with Rash, Encephalopathy, and Hemolytic Anemia. J Pediatric Infect Dis Soc. 2015 May 28. [Epub ahead of print] PubMed PMID: 26407265
  • O'Ryan M, Bandyopadhyay AS, Villena R, Espinoza M, Novoa J, Weldon WC, Oberste MS, Self S, Borate BR, Asturias EJ, Clemens R, Orenstein W, Jimeno J, Rüttimann R, Costa Clemens SA. Inactivated poliovirus vaccine given alone or in a sequential schedule with bivalent oral poliovirus vaccine in Chilean infants: a randomised, controlled, open-label, phase 4, non-inferiority study. Lancet Infect Dis. 2015 Aug 26. [Epub ahead of print] PubMed PMID: 26318714
  • Dutmer CM, Asturias EJ, Smith C, Dishop MK, Schmid DS, Bellini WJ, Tirosh I, Lee YN, Notarangelo LD, Gelfand EW. Late Onset Hypomorphic RAG2 Deficiency Presentation with Fatal Vaccine-Strain VZV Infection. J Clin Immunol. 2015 Oct 29. [Epub ahead of print] PubMed PMID: 26515615
  • Olson D, Lamb MM, Gaensbauer JT, Todd JK, Halsey NA, Asturias EJ. Risk Factors for Death and Major Morbidity in Guatemalan Children with Acute Bacterial Meningitis. Pediatr Infect Dis J. 2015 Jul;34(7):724-8. PubMed PMID: 26069947
  • Olson D, Birkholz M, Gaensbauer JT, Asturias EJ, Todd JK. Analysis of the pediatric health information system database as a surveillance tool for travel-associated infectious diseases. Am J Trop Med Hyg. 2015 May;92(5):1067-9. PubMed PMID: 25778506
  • Asturias EJ. Women scientist and the will to prevent hib disease. Pediatr Infect Dis J. 2014 Dec;33(12):1311. PubMed PMID: 25386972
  • Gaensbauer JT, Rakhola JT, Onyango-Makumbi C, Mubiru M, Westcott JE, Krebs NF, Asturias EJ, Fowler MG, McFarland E, Janoff EN. Impaired Haemophilus influenzae Type b Transplacental Antibody Transmission and Declining Antibody Avidity through the First Year of Life Represent Potential Vulnerabilities for HIV-Exposed but -Uninfected Infants. Clin Vaccine Immunol. 2014 Dec;21(12):1661-7. PubMed PMID: 25298109
  • Smith C, Lee-Miller C, Dishop MK, Cost C, Wang M, Asturias EJ. Multicentric castleman disease presenting with Fever. J Pediatr. 2014 Dec;165(6):1261-5. PubMed PMID: 25282064
  • Behrens RH, Cramer JP, Jelinek T, Shaw H, von Sonnenburg F, Wilbraham D, Weinke T, Bell DJ, Asturias E, Pauwells HL, Maxwell R, Paredes-Paredes M, Glenn GM, Dewasthaly S, Stablein DM, Jiang ZD, Dupont HL. Efficacy and safety of a patch vaccine containing heat-labile toxin from Escherichia coli against travellers' diarrhoea: a phase 3, randomised, double-blind, placebo-controlled field trial in travellers from Europe to Mexico and Guatemala. Lancet Infect Dis. 2013 Nov 28. [Epub ahead of print] PubMed PMID: 24291168
  • Behrens RH, Cramer JP, Jelinek T, Shaw H, von Sonnenburg F, Wilbraham D, Weinke T, Bell DJ, Asturias E, Pauwells HL, Maxwell R, Paredes-Paredes M, Glenn GM, Dewasthaly S, Stablein DM, Jiang ZD, Dupont HL. Efficacy and safety of a patch vaccine containing heat-labile toxin from Escherichia coli against travellers' diarrhoea: a phase 3, randomised, double-blind, placebo-controlled field trial in travellers from Europe to Mexico and Guatemala. Lancet Infect Dis. 2013 Nov 28. [Epub ahead of print] PubMed PMID: 24291168
  • Asturias EJ, Contreras-Roldan IL, Ram M, Garcia-Melgar AJ, Morales-Oquendo V, Hartman K, Rauscher M, Moulton LH, Halsey NA. Post-authorization safety surveillance of a liquid pentavalent vaccine in Guatemalan children. Vaccine. 2013 Dec 2;31(49):5909-14. PubMed PMID: 24055354
  • Tozzi AE, Asturias EJ, Balakrishnan MR, Halsey NA, Law B, Zuber PL. Assessment of causality of individual adverse events following immunization (AEFI): a WHO tool for global use. Vaccine. 2013 Oct 17;31(44):5041-6. PubMed PMID: 24021304
  • Gaensbauer JT, Press CA, Hollister JR, Asturias EJ. Procalcitonin: a marker of infection not subverted by treatment with interleukin-6 receptor inhibition. Pediatr Infect Dis J. 2013 Sep;32(9):1040. PubMed PMID: 24008743
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Professional Memberships

  • Infectious Diseases Society of America (IDSA), Fellow
  • American Academy of Pediatrics (AAP), Fellow
  • Latin American Society of Pediatric Infectious Diseases, Fellow
  • Pediatric Infectious Diseases Society (PIDS), Fellow
  • Academic Pediatric Association (APA), Member
  • Guatemala Society of Infectious Diseases, Member
  • Guatemalan Society of Pediatrics, Member
  • European Society of Pediatric Infectious Diseases, Member
  • Pediatric Academic Society, Member

Practice Locations

Children's Hospital Colorado
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Children's Hospital Colorado Child Health Clinic
13100 E Colfax Ave
Suite 300
Aurora, CO 80045
720-777-2740

Children's Hospital Colorado Special Care Clinic
13123 E 16th Ave
Aurora, CO 80045
720-777-6739

Hospital Affiliation
  • Children's Hospital Colorado

Specialty Information

Specialties
  • Pediatrics, Board Certification (1997, 2012)
  • Pediatric Infectious Diseases, Board Certification (2013)
  • American Board of Pediatrics - Pediatric Infectious Diseases, Board Certification (2013)
  • American Board of Pediatrics, Board Certification (1997)
Conditions & Treatments
  • Infections
  • Child and Teen Health
  • Infections - Bacterial Infections
  • Infections - Fungal Infections
  • Infections - Influenza
  • Infections - Pneumonia
  • Infections - Sexually Transmitted Diseases
  • Infections - Viral Infections
  • Primary Care
Clinical Interest for Patients
Tropical infectious diseases International adoption and infectious diseases Vaccine adverse events

General Information

Medical Schools:
  • MD, University of San Carlos School of Medicine (1989)
Internships:
  • University of Colorado (Children's Hospital Colorado) Program (1993)
Residency Programs:
  • University of Colorado (Children's Hospital Colorado) Program, Pediatrics (1995)
Fellowships:
  • Johns Hopkins University School of Medicine Program, Pediatric Infectious Diseases (1998)
Languages: English, Spanish
Department: Pediatrics-Infectious Diseases
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