Jeffrey Moore, PhD
Associate Professor, Cell & Developmental Biology

Publications

  • Thomas EC, Ismael A, Moore JK. Ase1 domains dynamically slow anaphase spindle elongation and recruit Bim1 to the midzone. Mol Biol Cell. 2020 Nov 15;31(24):2733-2747. PubMed PMID: 32997572
  • Gudimchuk NB, Ulyanov EV, O'Toole E, Page CL, Vinogradov DS, Morgan G, Li G, Moore JK, Szczesna E, Roll-Mecak A, Ataullakhanov FI, Richard McIntosh J. Mechanisms of microtubule dynamics and force generation examined with computational modeling and electron cryotomography. Nat Commun. 2020 Jul 28;11(1):3765. PubMed PMID: 32724196
  • Li G, Moore JK. Microtubule dynamics at low temperature: evidence that tubulin recycling limits assembly. Mol Biol Cell. 2020 May 15;31(11):1154-1166. PubMed PMID: 32213119
  • Buscaglia G, Northington KR, Moore JK, Bates EA. Reduced TUBA1A Tubulin Causes Defects in Trafficking and Impaired Adult Motor Behavior. eNeuro. 2020 Mar Apr;7(2). PubMed PMID: 32184299
  • Estrem C, Moore JK. Help or hindrance: how do microtubule-based forces contribute to genome damage and repair?. Curr Genet. 2020 Apr;66(2):303-311. PubMed PMID: 31501990
  • Aiken J, Buscaglia G, Aiken AS, Moore JK, Bates EA. Tubulin mutations in brain development disorders: Why haploinsufficiency does not explain TUBA1A tubulinopathies. Cytoskeleton (Hoboken). 2020 Mar;77(3-4):40-54. PubMed PMID: 31574570
  • Aiken J, Buscaglia G, Aiken AS, Moore JK, Bates EA. Tubulin mutations in brain development disorders: Why haploinsufficiency does not explain TUBA1A tubulinopathies. Cytoskeleton (Hoboken). 2019 Oct 1. [Epub ahead of print] PubMed PMID: 31574570
  • Estrem C, Moore JK. Help or hindrance: how do microtubule-based forces contribute to genome damage and repair?. Curr Genet. 2019 Sep 9. [Epub ahead of print] PubMed PMID: 31501990
  • Estrem C, Moore JK. Astral microtubule forces alter nuclear organization and inhibit DNA repair in budding yeast. Mol Biol Cell. 2019 Jul 22;30(16):2000-2013. PubMed PMID: 31067146
  • Aiken J, Moore JK, Bates EA. TUBA1A mutations identified in lissencephaly patients dominantly disrupt neuronal migration and impair dynein activity. Hum Mol Genet. 2019 Apr 15;28(8):1227-1243. PubMed PMID: 30517687
  • Fees CP, Moore JK. A unified model for microtubule rescue. Mol Biol Cell. 2019 Mar 15;30(6):753-765. PubMed PMID: 30672721
  • Aiken J, Moore JK, Bates EA. TUBA1A mutations identified in lissencephaly patients dominantly disrupt neuronal migration and impair dynein activity. Hum Mol Genet. 2018 Dec 4. [Epub ahead of print] PubMed PMID: 30517687
  • Aiken J, Buscaglia G, Bates EA, Moore JK. The a -Tubulin gene TUBA1A in Brain Development: A Key Ingredient in the Neuronal Isotype Blend. J Dev Biol. 2017 Sep;5(3). PubMed PMID: 29057214
  • Estrem C, Fees CP, Moore JK. Dynein is regulated by the stability of its microtubule track. J Cell Biol. 2017 Jul 3;216(7):2047-2058. PubMed PMID: 28572117
  • Fees CP, Estrem C, Moore JK. High-resolution Imaging and Analysis of Individual Astral Microtubule Dynamics in Budding Yeast. J Vis Exp. 2017 Apr 20;(122). PubMed PMID: 28448000
  • Gartz Hanson M, Aiken J, Sietsema DV, Sept D, Bates EA, Niswander L, Moore JK. Novel a-tubulin mutation disrupts neural development and tubulin proteostasis. Dev Biol. 2016 Jan 15;409(2):406-19. PubMed PMID: 26658218
  • Mangan AJ, Sietsema DV, Li D, Moore JK, Citi S, Prekeris R. Cingulin and actin mediate midbody-dependent apical lumen formation during polarization of epithelial cells. Nat Commun. 2016 Aug 3;7:12426. PubMed PMID: 27484926
  • Fees CP, Aiken J, O'Toole ET, Giddings TH Jr, Moore JK. The negatively charged carboxy-terminal tail of ß-tubulin promotes proper chromosome segregation. Mol Biol Cell. 2016 Jun 1;27(11):1786-96. PubMed PMID: 27053662
  • Gartz Hanson M, Aiken J, Sietsema DV, Sept D, Bates EA, Niswander L, Moore JK. Novel a-tubulin mutation disrupts neural development and tubulin proteostasis. Dev Biol. 2016 Jan 15;409(2):406-19. PubMed PMID: 26658218
  • Nithianantham S, Le S, Seto E, Jia W, Leary J, Corbett KD, Moore JK, Al-Bassam J. Tubulin cofactors and Arl2 are cage-like chaperones that regulate the soluble aß-tubulin pool for microtubule dynamics. Elife. 2015 Jul 24;4. PubMed PMID: 26208336
  • Aiken J, Sept D, Costanzo M, Boone C, Cooper JA, Moore JK. Genome-wide analysis reveals novel and discrete functions for tubulin carboxy-terminal tails. Curr Biol. 2014 Jun 16;24(12):1295-303. PubMed PMID: 24835459
  • Moore JK. Stopped in its tracks: negative regulation of the dynein motor by the yeast protein She1. Bioessays. 2013 Aug;35(8):677-82. PubMed PMID: 23666903
  • Siglin AE, Sun S, Moore JK, Tan S, Poenie M, Lear JD, Polenova T, Cooper JA, Williams JC. Dynein and dynactin leverage their bivalent character to form a high-affinity interaction. PLoS One. 2013;8(4):e59453. PubMed PMID: 23577064
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General Information

Department: Cell & Developmental Biology
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