Jeffrey Moore, PhD
Associate Professor, Cell & Developmental Biology

Publications

  • Park K, Hoff KJ, Wethekam L, Stence N, Saenz M, Moore JK. Kinetically Stabilizing Mutations in Beta Tubulins Create Isotype-Specific Brain Malformations. Front Cell Dev Biol. 2021;9:765992. PubMed PMID: 34869359
  • Moore JK, Wethekam L. Specialist a-tubulins for pluralist microtubules. J Cell Biol. 2021 Dec 6;220(12). PubMed PMID: 34762120
  • Zhang G, Dong Z, Gimple RC, Wolin A, Wu Q, Qiu Z, Wood LM, Shen JZ, Jiang L, Zhao L, Lv D, Prager BC, Kim LJY, Wang X, Zhang L, Anderson RL, Moore JK, Bao S, Keller TH, Lin G, Kang C, Hamerlik P, Zhao R, Ford HL, Rich JN. Targeting EYA2 tyrosine phosphatase activity in glioblastoma stem cells induces mitotic catastrophe. J Exp Med. 2021 Nov 1;218(11). PubMed PMID: 34617969
  • Thomas EC, Ismael A, Moore JK. Ase1 domains dynamically slow anaphase spindle elongation and recruit Bim1 to the midzone. Mol Biol Cell. 2020 Nov 15;31(24):2733-2747. PubMed PMID: 32997572
  • Gudimchuk NB, Ulyanov EV, O'Toole E, Page CL, Vinogradov DS, Morgan G, Li G, Moore JK, Szczesna E, Roll-Mecak A, Ataullakhanov FI, Richard McIntosh J. Mechanisms of microtubule dynamics and force generation examined with computational modeling and electron cryotomography. Nat Commun. 2020 Jul 28;11(1):3765. PubMed PMID: 32724196
  • Li G, Moore JK. Microtubule dynamics at low temperature: evidence that tubulin recycling limits assembly. Mol Biol Cell. 2020 May 15;31(11):1154-1166. PubMed PMID: 32213119
  • Buscaglia G, Northington KR, Moore JK, Bates EA. Reduced TUBA1A Tubulin Causes Defects in Trafficking and Impaired Adult Motor Behavior. eNeuro. 2020 Mar Apr;7(2). PubMed PMID: 32184299
  • Estrem C, Moore JK. Help or hindrance: how do microtubule-based forces contribute to genome damage and repair?. Curr Genet. 2020 Apr;66(2):303-311. PubMed PMID: 31501990
  • Aiken J, Buscaglia G, Aiken AS, Moore JK, Bates EA. Tubulin mutations in brain development disorders: Why haploinsufficiency does not explain TUBA1A tubulinopathies. Cytoskeleton (Hoboken). 2020 Mar;77(3-4):40-54. PubMed PMID: 31574570
  • Aiken J, Buscaglia G, Aiken AS, Moore JK, Bates EA. Tubulin mutations in brain development disorders: Why haploinsufficiency does not explain TUBA1A tubulinopathies. Cytoskeleton (Hoboken). 2019 Oct 1. [Epub ahead of print] PubMed PMID: 31574570
  • Estrem C, Moore JK. Help or hindrance: how do microtubule-based forces contribute to genome damage and repair?. Curr Genet. 2019 Sep 9. [Epub ahead of print] PubMed PMID: 31501990
  • Estrem C, Moore JK. Astral microtubule forces alter nuclear organization and inhibit DNA repair in budding yeast. Mol Biol Cell. 2019 Jul 22;30(16):2000-2013. PubMed PMID: 31067146
  • Aiken J, Moore JK, Bates EA. TUBA1A mutations identified in lissencephaly patients dominantly disrupt neuronal migration and impair dynein activity. Hum Mol Genet. 2019 Apr 15;28(8):1227-1243. PubMed PMID: 30517687
  • Fees CP, Moore JK. A unified model for microtubule rescue. Mol Biol Cell. 2019 Mar 15;30(6):753-765. PubMed PMID: 30672721
  • Aiken J, Moore JK, Bates EA. TUBA1A mutations identified in lissencephaly patients dominantly disrupt neuronal migration and impair dynein activity. Hum Mol Genet. 2018 Dec 4. [Epub ahead of print] PubMed PMID: 30517687
  • Aiken J, Buscaglia G, Bates EA, Moore JK. The a -Tubulin gene TUBA1A in Brain Development: A Key Ingredient in the Neuronal Isotype Blend. J Dev Biol. 2017 Sep;5(3). PubMed PMID: 29057214
  • Estrem C, Fees CP, Moore JK. Dynein is regulated by the stability of its microtubule track. J Cell Biol. 2017 Jul 3;216(7):2047-2058. PubMed PMID: 28572117
  • Fees CP, Estrem C, Moore JK. High-resolution Imaging and Analysis of Individual Astral Microtubule Dynamics in Budding Yeast. J Vis Exp. 2017 Apr 20;(122). PubMed PMID: 28448000
  • Gartz Hanson M, Aiken J, Sietsema DV, Sept D, Bates EA, Niswander L, Moore JK. Novel a-tubulin mutation disrupts neural development and tubulin proteostasis. Dev Biol. 2016 Jan 15;409(2):406-19. PubMed PMID: 26658218
  • Mangan AJ, Sietsema DV, Li D, Moore JK, Citi S, Prekeris R. Cingulin and actin mediate midbody-dependent apical lumen formation during polarization of epithelial cells. Nat Commun. 2016 Aug 3;7:12426. PubMed PMID: 27484926
  • Fees CP, Aiken J, O'Toole ET, Giddings TH Jr, Moore JK. The negatively charged carboxy-terminal tail of ß-tubulin promotes proper chromosome segregation. Mol Biol Cell. 2016 Jun 1;27(11):1786-96. PubMed PMID: 27053662
  • Gartz Hanson M, Aiken J, Sietsema DV, Sept D, Bates EA, Niswander L, Moore JK. Novel a-tubulin mutation disrupts neural development and tubulin proteostasis. Dev Biol. 2016 Jan 15;409(2):406-19. PubMed PMID: 26658218
  • Nithianantham S, Le S, Seto E, Jia W, Leary J, Corbett KD, Moore JK, Al-Bassam J. Tubulin cofactors and Arl2 are cage-like chaperones that regulate the soluble aß-tubulin pool for microtubule dynamics. Elife. 2015 Jul 24;4. PubMed PMID: 26208336
  • Aiken J, Sept D, Costanzo M, Boone C, Cooper JA, Moore JK. Genome-wide analysis reveals novel and discrete functions for tubulin carboxy-terminal tails. Curr Biol. 2014 Jun 16;24(12):1295-303. PubMed PMID: 24835459
  • Moore JK. Stopped in its tracks: negative regulation of the dynein motor by the yeast protein She1. Bioessays. 2013 Aug;35(8):677-82. PubMed PMID: 23666903
  • Siglin AE, Sun S, Moore JK, Tan S, Poenie M, Lear JD, Polenova T, Cooper JA, Williams JC. Dynein and dynactin leverage their bivalent character to form a high-affinity interaction. PLoS One. 2013;8(4):e59453. PubMed PMID: 23577064
View All (26 Total) View Less

General Information

Department: Cell & Developmental Biology
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