Marc Mathias, MD
Associate Professor, Ophthalmology

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Medical School:
  • MD, Ohio State University College of Medicine (2008)
Undergraduate School:
  • BS, Boston College (MA) (2004)
Internship:
  • Ohio State University Hospital Program (2009)
Residency:
  • University of Colorado (University Hospital) Program, Ophthalmology (2012)
Fellowships:
  • University of Colorado, Vitreoretinal Disease and Surgery (2014)
Languages: English
Department: Ophthalmology

Recognition & Awards

  • Ambassador, American Academy of Ophthalmology Advocacy Ambassador Program (2011)
    To attend Congressional Advocacy Day, Washington, D.C.

Teaching

  • Assistant Professor (2014)
    School of Medicine, Ophthalmology
    Vitreoretinal Disease and Surgery

Publications

  • Bommakanti N, Young BK, Sisk RA, Berrocal AM, Duncan JL, Bakall B, Mathias MT, Ahmed I, Chorfi S, Comander J, Nagiel A, Besirli CG. Classification and Growth Rate of Chorioretinal Atrophy after Voretigene Neparvovec-Rzyl for RPE65-Mediated Retinal Degeneration. Ophthalmol Retina. 2024 Jan;8(1):42-48. PubMed PMID: 37660736
  • Fonteh CN, Palestine AG, Wagner BD, Patnaik JL, Mathias MT, Manoharan N, Mandava N, Baldermann R, De Carlo T, Lynch AM. RANTES (CCL5) in Patients With Geographic Atrophy Age-Related Macular Degeneration. Transl Vis Sci Technol. 2023 Jan 3;12(1):19. PubMed PMID: 36633873
  • Marin AI, Petrash CC, Jolly A, Gange WS, Mathias MT. A case of venous overload choroidopathy in the setting of superior vena cava syndrome. Am J Ophthalmol Case Rep. 2023 Dec;32:101918. PubMed PMID: 37680306
  • Rajeswaren V, Wagner BD, Patnaik JL, Mandava N, Mathias MT, Manoharan N, De Carlo Forest TE, Gnanaraj R, Lynch AM, Palestine AG. Interleukin-4 Plasma Levels Stratified by Sex in Intermediate Age-Related Macular Degeneration and Geographic Atrophy. Transl Vis Sci Technol. 2023 Aug 1;12(8):1. PubMed PMID: 37526620
  • Lynch AM, McReynolds AJ, Wittel RJ, Mathias MT, Manoharan N, Emerick LM, Brocious ML, Patnaik JL. The use of social and digital media to recruit patients with early and intermediate age-related macular degeneration. Clin Exp Ophthalmol. 2023 May-Jun;51(4):398-401. PubMed PMID: 37062710
  • Fonteh CN, Palestine AG, Wagner BD, Patnaik JL, Mathias MT, Manoharan N, Mandava N, Baldermann R, De Carlo T, Lynch AM. RANTES (CCL5) in Patients With Geographic Atrophy Age-Related Macular Degeneration. Transl Vis Sci Technol. 2023 Jan 3;12(1):19. PubMed PMID: 36633873
  • Fonteh CN, Mathias MT, Mandava N, Manoharan N, Lynch AM, Navo R, Patnaik JL. Mental health and visual acuity in patients with age-related macular degeneration. BMC Ophthalmol. 2022 Oct 2;22(1):391. PubMed PMID: 36183081
  • Sidhu S, Lynch AM, Mandava N, Manoharan N, Mathias MT, Patnaik JL. Gender Differences in Visual Functioning Questionnaire Scores among Patients with Age-Related Macular Degeneration. Ophthalmic Epidemiol. 2022 Jul 17;:1-10. [Epub ahead of print] PubMed PMID: 35848204
  • Marin AI, Poppelaars F, Wagner BD, Palestine AG, Patnaik JL, Holers VM, Frazer-Abel AA, Mathias MT, Manoharan N, Fonteh CN, Mandava N, Lynch AM. Sex and Age-Related Differences in Complement Factors Among Patients With Intermediate Age-Related Macular Degeneration. Transl Vis Sci Technol. 2022 May 2;11(5):22. PubMed PMID: 35594041
  • Pelak VS, Paez YM, Patnaik JL, Holden SK, Subramanian PS, Mathias MT, Mandava N, Lynch AM. An Exploratory Study to Investigate the Utility of Clinical Screening for Neurodegenerative Disease in Age-Related Eye Disease Research. J Neuroophthalmol. 2022 Sep 1;42(3):346-352. PubMed PMID: 35483065
  • Gelinas N, Lynch AM, Mathias MT, Palestine AG, Mandava N, Christopher KL, Patnaik JL. Gender as an effect modifier in the relationship between hypertension and reticular pseudodrusen in patients with early or intermediate age-related macular degeneration. Int J Ophthalmol. 2022;15(3):461-465. PubMed PMID: 35310058
  • Li KV, Flores-Bellver M, Aparicio-Domingo S, Petrash C, Cobb H, Chen C, Canto-Soler MV, Mathias MT. A Surgical Kit for Stem Cell-Derived Retinal Pigment Epithelium Transplants: Collection, Transportation, and Subretinal Delivery. Front Cell Dev Biol. 2022;10:813538. PubMed PMID: 35252183
  • Fonteh CN, Palestine AG, Wagner BD, Patnaik JL, Mathias MT, Mandava N, Baldermann R, Lynch AM. Sex Differences in RANTES (CCL5) in Patients With Intermediate Age-Related Macular Degeneration (AMD) and Controls With no AMD. Transl Vis Sci Technol. 2022 Feb 1;11(2):12. PubMed PMID: 35133404
  • Wagner BD, Patnaik JL, Palestine AG, Frazer-Abel AA, Baldermann R, Holers VM, Mathias MT, Mandava N, Lynch AM. Association of Systemic Inflammatory Factors with Progression to Advanced Age-related Macular Degeneration. Ophthalmic Epidemiol. 2022 Apr;29(2):139-148. PubMed PMID: 33827374
  • Patnaik JL, Lynch AM, Wagner BD, Echalier EL, Kohrt WM, Mathias MT, Siringo FS, Palestine AG, Mandava N. Hormone Therapy as a Protective Factor for Age-Related Macular Degeneration. Ophthalmic Epidemiol. 2020 Apr;27(2):148-154. PubMed PMID: 31813321
  • Patnaik JL, Lynch AM, Pecen PE, Jasso M, Hanson K, Mathias MT, Palestine AG, Mandava N. The impact of advanced age-related macular degeneration on the National Eye Institute's Visual Function Questionnaire-25. Acta Ophthalmol. 2020 Dec 30. [Epub ahead of print] PubMed PMID: 33377625
  • Lynch AM, Wagner BD, Palestine AG, Janjic N, Patnaik JL, Mathias MT, Siringo FS, Mandava N. Plasma Biomarkers of Reticular Pseudodrusen and the Risk of Progression to Advanced Age-Related Macular Degeneration. Transl Vis Sci Technol. 2020 Sep;9(10):12. PubMed PMID: 32974084
  • Lynch AM, Palestine AG, Wagner BD, Patnaik JL, Frazier-Abel AA, Mathias MT, Siringo FS, Holers VM, Mandava N. Complement factors and reticular pseudodrusen in intermediate age-related macular degeneration staged by multimodal imaging. BMJ Open Ophthalmol. 2020;5(1):e000361. PubMed PMID: 32509962
  • Patnaik JL, Lynch AM, Wagner BD, Echalier EL, Kohrt WM, Mathias MT, Siringo FS, Palestine AG, Mandava N. Hormone Therapy as a Protective Factor for Age-Related Macular Degeneration. Ophthalmic Epidemiol. 2020 Apr;27(2):148-154. PubMed PMID: 31813321
  • Lynch AM, Mandava N, Patnaik JL, Frazer-Abel AA, Wagner BD, Palestine AG, Mathias MT, Siringo FS, Cathcart JN, Holers VM. Systemic activation of the complement system in patients with advanced age-related macular degeneration. Eur J Ophthalmol. 2020 Sep;30(5):1061-1068. PubMed PMID: 31203676
  • Lynch AM, Wagner BD, Weiss SJ, Wall KM, Palestine AG, Mathias MT, Siringo FS, Cathcart JN, Patnaik JL, Drolet DW, Janjic N, Mandava N. Proteomic Profiles in Advanced Age-Related Macular Degeneration Using an Aptamer-Based Proteomic Technology. Transl Vis Sci Technol. 2019 Jan;8(1):14. PubMed PMID: 30697465
  • Lynch AM, Mandava N, Patnaik JL, Frazer-Abel AA, Wagner BD, Palestine AG, Mathias MT, Siringo FS, Cathcart JN, Holers VM. Systemic activation of the complement system in patients with advanced age-related macular degeneration. Eur J Ophthalmol. 2019 Jun 17;:1120672119857896. [Epub ahead of print] PubMed PMID: 31203676
  • Patnaik JL, Pecen PE, Hanson K, Lynch AM, Cathcart JN, Siringo FS, Mathias MT, Mandava N. Driving and Visual Acuity in Patients with Age-Related Macular Degeneration. Ophthalmol Retina. 2019 Apr;3(4):336-342. PubMed PMID: 31014686
  • Schofield JR, Palestine AG, Pelak V, Mathias MT. Deep capillary retinal ischemia and high-titer prothrombin-associated antiphospholipid antibodies: A case series of three patients. Am J Ophthalmol Case Rep. 2019 Jun;14:105-109. PubMed PMID: 31011663
  • Lynch AM, Wagner BD, Weiss SJ, Wall KM, Palestine AG, Mathias MT, Siringo FS, Cathcart JN, Patnaik JL, Drolet DW, Janjic N, Mandava N. Proteomic Profiles in Advanced Age-Related Macular Degeneration Using an Aptamer-Based Proteomic Technology. Transl Vis Sci Technol. 2019 Jan;8(1):14. PubMed PMID: 30697465
  • Lynch AM, Patnaik JL, Cathcart JN, Mathias MT, Siringo FS, Lacey Echalier E, Wagner BD, Oliver SCN, Pecen PE, Olson JL, Fine SL, Palestine AG, Mandava N. COLORADO AGE-RELATED MACULAR DEGENERATION REGISTRY: Design and Clinical Risk Factors of the Cohort. Retina. 2019 Apr;39(4):656-663. PubMed PMID: 29283981
  • Lynch AM, Patnaik JL, Cathcart JN, Mathias MT, Siringo FS, Lacey Echalier E, Wagner BD, Oliver SCN, Pecen PE, Olson JL, Fine SL, Palestine AG, Mandava N. COLORADO AGE-RELATED MACULAR DEGENERATION REGISTRY: Design and Clinical Risk Factors of the Cohort. Retina. 2018 Jan 31. [Epub ahead of print] PubMed PMID: 29283981
  • Lynch AM, Patnaik JL, Cathcart JN, Mathias MT, Siringo FS, Echalier LL, Wagner BD, Oliver SCN, Pecen PE, Olson JL, Fine SL, Palestine AG, Mandava N. COLORADO AGE-RELATED MACULAR DEGENERATION REGISTRY: Design and Clinical Risk Factors of the Cohort. Retina. 2017 Dec 27. [Epub ahead of print] PubMed PMID: 29283981
  • Smith JM, Hwang RY, Siringo F, Quiroz-Mercado H, Oliver SC, Mandava N, Mathias MT, Olson JL. CONCURRENT ENDOPHTHALMITIS AND ANTERIOR SEGMENT ISCHEMIA AFTER STRABISMUS SURGERY. Retin Cases Brief Rep. 2017 Spring;11(2):148-151. PubMed PMID: 27124792
  • Smith JM, Hwang RY, Siringo F, Quiroz-Mercado H, Oliver SC, Mandava N, Mathias MT, Olson JL. CONCURRENT ENDOPHTHALMITIS AND ANTERIOR SEGMENT ISCHEMIA AFTER STRABISMUS SURGERY. Retin Cases Brief Rep. 2016 Apr 27. [Epub ahead of print] PubMed PMID: 27124792
  • Smith JM, Mathias MT, Oliver SC, Mandava N, Olson JL, Quiroz-Mercado H, Palestine AG. The influence of needle gauge and infection source on vitreous aspirate cultures. Br J Ophthalmol. 2016 Apr;100(4):453-5. PubMed PMID: 26269533
  • Smith JM, Mathias MT, Oliver SC, Mandava N, Olson JL, Quiroz-Mercado H, Palestine AG. The influence of needle gauge and infection source on vitreous aspirate cultures. Br J Ophthalmol. 2015 Aug 12. [Epub ahead of print] PubMed PMID: 26269533
  • Salcedo-Villanueva G, Harasawa M, Velez-Montoya R, Mathias MT, Siringo FS, Olson JL, Oliver SC, Mandava N, Quiroz-Mercado H. Spectral domain optical coherence tomographic analysis of healthy retina in branch retinal vein occlusion and its response to antiangiogenic therapy. Retina. 2015 Apr;35(4):704-14. PubMed PMID: 25313712
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Professional Memberships

  • American Academy of Ophthalmology (AAO), Member
  • Alpha Omega Alpha Medical Honor Society (AOA), Member
  • American Society of Retina Specialists (ASRS), Member
  • The Association for Research in Vision and Ophthalmology (ARVO), Member
  • Colorado Society of Eye Physicians and Surgeons (CSEPS), Member

Practice Locations

UCHealth Sue Anschutz-Rodgers Eye Center
1675 Aurora Ct
Aurora, CO 80045
720-848-2020

UCHealth - Eye Center - Lone Tree
9552 Park Meadows Drive
Suite 100
Lone Tree, CO 80124
720-553-2255

Hospital Affiliation
  • University of Colorado Hospital
  • Children's Hospital Colorado

Specialty Information

Specialties
  • Ophthalmology, Board Certification (2014)
  • Vitreoretinal Disease and Surgery, Specialized Training (2014)
Conditions & Treatments
  • Eyes and Vision - Macular Degeneration
  • Eyes and Vision - Retinal Detachment
  • Eyes and Vision
  • Endocrine System (Hormones) - Diabetic Retinopathy
  • Endocrine System (Hormones)
  • Surgery - Eye and/or Orbital Surgery
  • Surgery
  • Eyes and Vision - Diabetic Eye Disease

General Information

Medical Schools:
  • MD, Ohio State University College of Medicine (2008)
Undergraduate Schools:
  • BS, Boston College (MA) (2004)
Internships:
  • Ohio State University Hospital Program (2009)
Residency Programs:
  • University of Colorado (University Hospital) Program, Ophthalmology (2012)
Fellowships:
  • University of Colorado, Vitreoretinal Disease and Surgery (2014)
Download CV
Languages: English
Department: Ophthalmology
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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