Blair Fennimore, MD
Associate Professor, Medicine-Gastroenterology

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Medical School:
  • MD, Wake Forest University School of Medicine (2006)
Undergraduate School:
  • BS, University of North Carolina–Chapel Hill (NC) (2002)
Internship:
  • University of Colorado (University Hospital) Program (2007)
Residency:
  • University of Colorado (University Hospital) Program, Internal Medicine (2009)
Fellowships:
  • University of Colorado (University Hospital) Program, Gastroenterology (2012)
Languages: English
Department: Medicine-Gastroenterology

Research Interests

My reserach activities are focused on investigating the underyling causes and treatment of inflammatory bowel disease (IBD). Specicially, I am interested in new blood vessel formation within the intestines (angiogenesis) and its contributions to gut inflammation.

Publications

  • Gao RY, Shearn CT, Orlicky DJ, Battista KD, Alexeev EE, Cartwright IM, Lanis JM, Kostelecky RE, Ju C, Colgan SP, Fennimore BP. Bile acids modulate colonic MAdCAM-1 expression in a murine model of combined cholestasis and colitis. Mucosal Immunol. 2020 Oct 1. [Epub ahead of print] PubMed PMID: 33004979
  • Scott FI, Hans AK, Gerich ME, Fennimore B, Mamtani R, Vajravelu RK, Lewis JD. Identification of the Most Effective Position for Ustekinumab in Treatment Algorithms for Crohn's Disease. Clin Gastroenterol Hepatol. 2020 Aug 12. [Epub ahead of print] PubMed PMID: 32801006
  • deZoeten EF, Battista KD, Colson SB, Lovell MA, Kessler BE, Isfort RW, Fennimore BP, Onyiah JC, Kao DJ, Yeckes A, Keely S, Murray M, Hoffenberg EJ, Colgan SP, Gerich ME. Markers of Hypoxia Correlate with Histologic and Endoscopic Severity of Colitis in Inflammatory Bowel Disease. Hypoxia (Auckl). 2020;8:1-12. PubMed PMID: 32104717
  • Coleman SL, Neff CP, Li SX, Armstrong AJS, Schneider JM, Sen S, Fennimore B, Campbell TB, Lozupone CA, Palmer BE. Can gut microbiota of men who have sex with men influence HIV transmission?. Gut Microbes. 2020 May 3;11(3):610-619. PubMed PMID: 32036739
  • Scott FI, Luo M, Shah Y, Lasch K, Vajravelu RK, Mamtani R, Fennimore B, Gerich ME, Lewis JD. Identification of the Most Cost-effective Position of Vedolizumab Among the Available Biologic Drugs for the Treatment of Ulcerative Colitis. J Crohns Colitis. 2020 Jun 19;14(5):575-587. PubMed PMID: 31901085
  • Cartwright IM, Curtis VF, Lanis JM, Alexeev EE, Welch N, Goldberg MS, Schaefer REM, Gao RY, Chun C, Fennimore B, Onyiah JC, Gerich ME, Dempsey PJ, Colgan SP. Adaptation to inflammatory acidity through neutrophil-derived adenosine regulation of SLC26A3. Mucosal Immunol. 2020 Mar;13(2):230-244. PubMed PMID: 31792360
  • Cartwright IM, Curtis VF, Lanis JM, Alexeev EE, Welch N, Goldberg MS, Schaefer REM, Gao RY, Chun C, Fennimore B, Onyiah JC, Gerich ME, Dempsey PJ, Colgan SP. Adaptation to inflammatory acidity through neutrophil-derived adenosine regulation of SLC26A3. Mucosal Immunol. 2019 Dec 2. [Epub ahead of print] PubMed PMID: 31792360
  • Shearn CT, Fennimore B, Orlicky DJ, Gao YR, Saba LM, Battista KD, Aivazidis S, Assiri M, Harris PS, Michel C, Merrill GF, Schmidt EE, Colgan SP, Petersen DR. Cholestatic liver disease results increased production of reactive aldehydes and an atypical periportal hepatic antioxidant response. Free Radic Biol Med. 2019 Nov 1;143:101-114. PubMed PMID: 31377417
  • Regner EH, Ohri N, Stahly A, Gerich ME, Fennimore BP, Ir D, Jubair WK, Görg C, Siebert J, Robertson CE, Caplan L, Frank DN, Kuhn KA. Functional intraepithelial lymphocyte changes in inflammatory bowel disease and spondyloarthritis have disease specific correlations with intestinal microbiota. Arthritis Res Ther. 2018 Jul 20;20(1):149. PubMed PMID: 30029674
  • Glover LE, Fennimore B, Wingfield M. Inflammatory Bowel Disease: Influence and Implications in Reproduction. Inflamm Bowel Dis. 2016 Nov;22(11):2724-2732. PubMed PMID: 27537054
  • Kriss M, Kaplan J, Fennimore B. A rare cause of postprandial abdominal pain and nausea. Gastroenterology. 2015 Nov;149(6):e11-2. PubMed PMID: 26433105
  • Weissmüller T, Glover LE, Fennimore B, Curtis VF, MacManus CF, Ehrentraut SF, Campbell EL, Scully M, Grove BD, Colgan SP. HIF-dependent regulation of AKAP12 (gravin) in the control of human vascular endothelial function. FASEB J. 2014 Jan;28(1):256-64. PubMed PMID: 24029533
  • Weissmüller T, Glover LE, Fennimore B, Curtis VF, MacManus CF, Ehrentraut SF, Campbell EL, Scully M, Grove BD, Colgan SP. HIF-dependent regulation of AKAP12 (gravin) in the control of human vascular endothelial function. FASEB J. 2014 Jan;28(1):256-64. PubMed PMID: 24029533
  • Colgan SP, Fennimore B, Ehrentraut SF. Adenosine and gastrointestinal inflammation. J Mol Med (Berl). 2013 Feb;91(2):157-64. PubMed PMID: 23296303
  • Austin GL, Fennimore B, Ahnen DJ. Can colonoscopy remain cost-effective for colorectal cancer screening? The impact of practice patterns and the Will Rogers phenomenon on costs. Am J Gastroenterol. 2013 Mar;108(3):296-301. PubMed PMID: 23208273
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Professional Memberships

  • Crohn's & Colitis Foundation of America (CCFA), Member
  • American College of Gastroenterology (ACG), Member
  • American Gastroenterological Association (AGA), Member
  • American Society for Gastrointestinal Endoscopy (ASGE), Member
  • American Association for the Study of Liver Disease (AASLD), Member

Practice Locations

Digestive Health Center - Anschutz
1635 Aurora Ct
5th Floor
Aurora, CO 80045
720-848-2777

Crohn's and Colitis Center - Anschutz
1635 Aurora Ct
6th Floor
Aurora, CO 80045
720-848-2777

Hospital Affiliation
  • University of Colorado Hospital

Specialty Information

Specialties
  • Internal Medicine, Board Certification (2009)
  • Gastroenterology
Conditions & Treatments
  • Digestive System - Inflammatory Bowel Disease (IBD): Crohn’s disease, ulcerative colitis, microscopic colitis
  • Digestive System
Clinical Interests
My main clinical interest is in the medical and endoscopic management of patients with Inflammatory Bowel Disease (IBD) including Crohn's Disease and Ulcerative Colitis. The UCH Crohn's and Colitis Center utilizes a multi-disciplinary team of IBD focused clinicians and support staff (nutritionsit, social workers, and nurse clinical coordinators) to provide cutting edge care for our IBD patients.

Care Philosophy
Utilizing a multidisciplinary and comprehensive diagnostic approach combined with cutting edge treatment options, I strive to provide the best healthcare possible for my patients.

Personal Interests
In my spare time, I enjoy spending time with my family, snowboarding, and endurance sports such as triathlon, cycling, and long distance running.

General Information

Medical Schools:
  • MD, Wake Forest University School of Medicine (2006)
Undergraduate Schools:
  • BS, University of North Carolina–Chapel Hill (NC) (2002)
Internships:
  • University of Colorado (University Hospital) Program (2007)
Residency Programs:
  • University of Colorado (University Hospital) Program, Internal Medicine (2009)
Fellowships:
  • University of Colorado (University Hospital) Program, Gastroenterology (2012)
Languages: English
Department: Medicine-Gastroenterology
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