Tom Purcell, MD, MBA
Associate Professor, Medicine-Medical Oncology

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Medical School:
  • MD, Emory University School of Medicine (1996)
Graduate School :
  • MBA, University of Chicago (1991)
Undergraduate School:
  • BS, Millsaps College (MS) (1985)
Internship:
  • University of Texas Southwestern Medical School Program (1997)
Residency:
  • University of Texas Southwestern Medical School Program, Chief Resident, Internal Medicine (1999)
Fellowships:
  • Johns Hopkins University School of Medicine Program, Medical Oncology (2002)
Languages: English
Department: Medicine-Medical Oncology

Professional Titles

  • Associate Professor, Medicine-Medical Oncology
  • Executive Medical Director of Cancer Services; University of Colorado Hospital
  • Associate Director for Clinical Services; University of Colorado Cancer Center
  • Chief Medical Officer - UCHealth Highlands Ranch Hospital
  • System Director - Oncology Service Line; UCHealth

Recognition & Awards

  • Morton and Sandra Saffer Endowed Chair in Personalized Cancer Treatment and Oncology Leadership, University of Colorado School of Medicine (2018)
  • Statesman Award / Fellow of the American Society of Clinical Oncology, American Society of Clinical Oncology (2010)
  • Bohlinger Cancer Leadership Award, State of Montana Cancer Control Coalition (2010)

Research Interests

My research interests are focused in the development of new drugs to treat cancer. I am a member of the Phase I Developmental Therapeutics Team at the University of Colorado Cancer Center.

Publications

  • Dewberry LC, Wingrove LJ, Marsh MD, Glode AE, Schefter TE, Leong S, Purcell WT, McCarter MD. Pilot Prehabilitation Program for Patients With Esophageal Cancer During Neoadjuvant Therapy and Surgery. J Surg Res. 2019 Mar;235:66-72. PubMed PMID: 30691852
  • Patil T, Mushtaq R, Marsh S, Azelby C, Pujara M, Davies KD, Aisner DL, Purcell WT, Schenk EL, Pacheco JM, Bunn PA, Camidge DR, Doebele RC. Clinicopathologic Characteristics, Treatment Outcomes, and Acquired Resistance Patterns of Atypical EGFR Mutations and HER2 Alterations in Stage IV Non-Small-Cell Lung Cancer. Clin Lung Cancer. 2019 Nov 21. [Epub ahead of print] PubMed PMID: 31859066
  • Dewberry LC, Wingrove LJ, Marsh MD, Glode AE, Schefter TE, Leong S, Purcell WT, McCarter MD. Pilot Prehabilitation Program for Patients With Esophageal Cancer During Neoadjuvant Therapy and Surgery. J Surg Res. 2019 Mar;235:66-72. PubMed PMID: 30691852
  • Noonan SA, Patil T, Gao D, King GG, Thibault JR, Lu X, Bunn PA, Doebele RC, Purcell WT, Barón AE, Camidge DR. Baseline and On-Treatment Characteristics of Serum Tumor Markers in Stage IV Oncogene-Addicted Adenocarcinoma of the Lung. J Thorac Oncol. 2018 Jan;13(1):134-138. PubMed PMID: 28843358
  • Pacheco JM, Gao D, Smith D, Purcell WT, Hancock M, Bunn PA, Robin TP, Liu AK, Karam S, Gaspar LE, Kavanagh BD, Rusthoven CG, Aisner DL, Doebele RC, Camidge DR. Natural history and factors associated with overall survival in stage IV ALK rearranged non-small-cell lung cancer. J Thorac Oncol. 2018 Dec 29. [Epub ahead of print] PubMed PMID: 30599201
  • Patil T, Smith DE, Bunn PA, Aisner DL, Le AT, Hancock M, Purcell WT, Bowles DW, Camidge DR, Doebele RC. The Incidence of Brain Metastases in Stage IV ROS1-Rearranged Non-Small Cell Lung Cancer and Rate of Central Nervous System Progression on Crizotinib. J Thorac Oncol. 2018 Nov;13(11):1717-1726. PubMed PMID: 29981925
  • McCoach CE, Le AT, Gowan K, Jones K, Schubert L, Doak A, Estrada-Bernal A, Davies KD, Merrick DT, Bunn PA Jr, Purcell WT, Dziadziuszko R, Varella-Garcia M, Aisner DL, Camidge DR, Doebele RC. Resistance Mechanisms to Targeted Therapies in ROS1 ( ) and ALK ( ) Non-small Cell Lung Cancer. Clin Cancer Res. 2018 Jul 15;24(14):3334-3347. PubMed PMID: 29636358
  • McCoach CE, Blakely CM, Banks KC, Levy B, Chue BM, Raymond VM, Le AT, Lee CE, Diaz J, Waqar SN, Purcell WT, Aisner DL, Davies KD, Lanman RB, Shaw AT, Doebele RC. Clinical Utility of Cell-Free DNA for the Detection of ALK Fusions and Genomic Mechanisms of ALK Inhibitor Resistance in Non-Small Cell Lung Cancer. Clin Cancer Res. 2018 Jun 15;24(12):2758-2770. PubMed PMID: 29599410
  • Marker RJ, Cox-Martin E, Jankowski CM, Purcell WT, Peters JC. Evaluation of the effects of a clinically implemented exercise program on physical fitness, fatigue, and depression in cancer survivors. Support Care Cancer. 2018 Jun;26(6):1861-1869. PubMed PMID: 29270829
  • Robin TP, Camidge DR, Stuhr K, Nath SK, Breeze RE, Pacheco JM, Liu AK, Gaspar LE, Purcell WT, Doebele RC, Kavanagh BD, Rusthoven CG. Excellent Outcomes with Radiosurgery for Multiple Brain Metastases in ALK and EGFR Driven Non-Small Cell Lung Cancer. J Thorac Oncol. 2018 May;13(5):715-720. PubMed PMID: 29269007
  • Noonan SA, Patil T, Gao D, King GG, Thibault JR, Lu X, Bunn PA, Doebele RC, Purcell WT, Barón AE, Camidge DR. Baseline and On-Treatment Characteristics of Serum Tumor Markers in Stage IV Oncogene-Addicted Adenocarcinoma of the Lung. J Thorac Oncol. 2018 Jan;13(1):134-138. PubMed PMID: 28843358
  • Amini A, Yeh N, Jones BL, Bedrick E, Vinogradskiy Y, Rusthoven CG, Amini A, Purcell WT, Karam SD, Kavanagh BD, Guntupalli SR, Fisher CM. Perioperative Mortality in Nonelderly Adult Patients With Cancer: A Population-based Study Evaluating Health Care Disparities in the United States According to Insurance Status. Am J Clin Oncol. 2018 May;41(5):476-484. PubMed PMID: 27281264
  • Marker RJ, Cox-Martin E, Jankowski CM, Purcell WT, Peters JC. Evaluation of the effects of a clinically implemented exercise program on physical fitness, fatigue, and depression in cancer survivors. Support Care Cancer. 2017 Dec 21. [Epub ahead of print] PubMed PMID: 29270829
  • Robin TP, Camidge DR, Stuhr K, Nath SK, Breeze RE, Pacheco JM, Liu AK, Gaspar LE, Purcell WT, Doebele RC, Kavanagh BD, Rusthoven CG. Excellent Outcomes with Radiosurgery for Multiple Brain Metastases in ALK and EGFR Driven Non-Small Cell Lung Cancer. J Thorac Oncol. 2017 Dec 19. [Epub ahead of print] PubMed PMID: 29269007
  • Amini A, Jones BL, Stumpf P, Leong S, Lieu CH, Weekes C, Davis SL, Messersmith WA, Purcell WT, Ghosh D, Schefter T, Goodman KA. Patterns of Care for Locally Advanced Pancreatic Adenocarcinoma Using the National Cancer Database. Pancreas. 2017 Aug;46(7):904-912. PubMed PMID: 28697131
  • Gray JE, Heist RS, Starodub AN, Camidge DR, Kio EA, Masters GA, Purcell WT, Guarino MJ, Misleh J, Schneider CJ, Schneider BJ, Ocean A, Johnson T, Gandhi L, Kalinsky K, Scheff R, Messersmith WA, Govindan SV, Maliakal PP, Mudenda B, Wegener WA, Sharkey RM, Goldenberg DM. Therapy of Small Cell Lung Cancer (SCLC) with a Topoisomerase-I-inhibiting Antibody-Drug Conjugate (ADC) Targeting Trop-2, Sacituzumab Govitecan. Clin Cancer Res. 2017 Oct 1;23(19):5711-5719. PubMed PMID: 28679770
  • Heist RS, Guarino MJ, Masters G, Purcell WT, Starodub AN, Horn L, Scheff RJ, Bardia A, Messersmith WA, Berlin J, Ocean AJ, Govindan SV, Maliakal P, Mudenda B, Wegener WA, Sharkey RM, Goldenberg DM, Camidge DR. Therapy of Advanced Non-Small-Cell Lung Cancer With an SN-38-Anti-Trop-2 Drug Conjugate, Sacituzumab Govitecan. J Clin Oncol. 2017 Aug 20;35(24):2790-2797. PubMed PMID: 28548889
  • Shields PG, Herbst RS, Arenberg D, Benowitz NL, Bierut L, Luckart JB, Cinciripini P, Collins B, David S, Davis J, Hitsman B, Hyland A, Lang M, Leischow S, Park ER, Purcell WT, Selzle J, Silber A, Spencer S, Tanvetyanon T, Tiep B, Tindle HA, Tucker-Seeley R, Urbanic J, Hooper MW, Weksler B, Whitlock CW, Wood DE, Burns J, Scavone J. Smoking Cessation, Version 1.2016, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2016 Nov;14(11):1430-1468. PubMed PMID: 27799513
  • Chabon JJ, Simmons AD, Lovejoy AF, Esfahani MS, Newman AM, Haringsma HJ, Kurtz DM, Stehr H, Scherer F, Karlovich CA, Harding TC, Durkin KA, Otterson GA, Purcell WT, Camidge DR, Goldman JW, Sequist LV, Piotrowska Z, Wakelee HA, Neal JW, Alizadeh AA, Diehn M. Circulating tumour DNA profiling reveals heterogeneity of EGFR inhibitor resistance mechanisms in lung cancer patients. Nat Commun. 2016 Jun 10;7:11815. PubMed PMID: 27283993
  • Amini A, Yeh N, Jones BL, Bedrick E, Vinogradskiy Y, Rusthoven CG, Amini A, Purcell WT, Karam SD, Kavanagh BD, Guntupalli SR, Fisher CM. Perioperative Mortality in Nonelderly Adult Patients With Cancer: A Population-based Study Evaluating Health Care Disparities in the United States According to Insurance Status. Am J Clin Oncol. 2016 Jun 8. [Epub ahead of print] PubMed PMID: 27281264
  • Patil T, Aisner DL, Noonan SA, Bunn PA, Purcell WT, Carr LL, Camidge DR, Doebele RC. Malignant pleural disease is highly associated with subsequent peritoneal metastasis in patients with stage IV non-small cell lung cancer independent of oncogene status. Lung Cancer. 2016 Jun;96:27-32. PubMed PMID: 27133746
  • Rudek MA, Dasari A, Laheru D, He P, Jin R, Walker R, Taylor GE, Jimeno A, Donehower RC, Hidalgo M, Messersmith WA, Purcell WT. Phase 1 Study of ABT-751 in Combination With CAPIRI (Capecitabine and Irinotecan) and Bevacizumab in Patients With Advanced Colorectal Cancer. J Clin Pharmacol. 2016 Aug;56(8):966-73. PubMed PMID: 26632033
  • Meguid C, Ryan CE, Edil BH, Schulick RD, Gajdos C, Boniface M, Schefter TE, Purcell WT, McCarter M. Establishing a framework for building multidisciplinary programs. J Multidiscip Healthc. 2015;8:519-26. PubMed PMID: 26664132
  • Rudek MA, Dasari A, Laheru D, He P, Jin R, Walker R, Taylor GE, Jimeno A, Donehower RC, Hidalgo M, Messersmith WA, Purcell WT. Phase I Study of ABT-751 in Combination with CAPIRI (Capecitabine and Irinotecan) and Bevacizumab in Patients with Advanced Colorectal Cancer. J Clin Pharmacol. 2015 Dec 3. [Epub ahead of print] PubMed PMID: 26632033
  • Batley KE, Schade H, Purcell WT, Crawford ED. Subacute headache in a patient with metastatic gastric cancer. Oncology (Williston Park). 2015 May;29(5):390, C3. PubMed PMID: 25979548
  • Downs CG, Fowler L, Kolodziej M, Newcomer LH, Ogaily MS, Purcell WT, Winkelmann JC, Goodman C. The Affordable Care Act: where are we now? An NCCN roundtable. J Natl Compr Canc Netw. 2014 May;12(5 Suppl):745-7. PubMed PMID: 24853209
  • Bellamy L, Purcell WT. One institution's experience with implementation of EPIC/Beacon: lessons learned. Oncology (Williston Park). 2014 Feb;28(2):105-6, 108, C3. PubMed PMID: 24701696
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Professional Memberships

  • American Society of Clinical Oncology, Member
  • National Strength and Conditioning Association, Member
  • National Association of Sports Medicine, Member
  • Alpha Omega Alpha National Honor Society, Member

Practice Locations

UCH - Cancer Center
1665 Aurora Ct
Aurora, CO 80045
720-848-0300

CU Specialty Care at Highlands Ranch Cancer Care - Medical Oncology
1500 Park Central Drive, Suite 101
Highlands Ranch, CO 80129
720-516-1100

Lung Cancer Clinic - Anschutz
1665 Aurora Ct
Anschutz Cancer Pavilion
Aurora, CO 80045
720-848-0300

Hospital Affiliation
  • University of Colorado Hospital
  • UCHealth Highlands Ranch Hospital
Center Affiliations

Specialty Information

Specialties
  • Internal Medicine, Board Certification (1999, 2019)
  • Medical Oncology, Board Certification (2002, 2012)
Conditions & Treatments
  • Cancers - Gastroenterologic Cancer (Colon, Stomach, Esophageal, Liver)
  • Cancers - Lung Cancer
  • Cancers
  • Cancers - Anal Cancer
  • Cancers - Biliary Cancer
  • Cancers - Cancer Medicine
  • Cancers - Chemotherapy
  • Cancers - Pancreatic Cancer
Clinical Interests
I am a medical oncologist focusing on the treatment of gastrointestinal and lung cancers as well as experimental drug development.

Care Philosophy
I love being part of a team and want to be true partner in your cancer care. At the University of Colorado Cancer Center, we are able to bring the absolute best science, technology and multidisciplinary expertise to the clinic. As important, I hope to bring clear communication and compassion that you so deserve in your care. It is truly a privilege for me to be a physician serving cancer patients.

Personal Interests
In my spare time, I enjoy trying to stay in shape (I know, that sounds crazy!) and most sports, especially football. I have two beautiful daughters and enjoy travel and activities at my church.

General Information

Medical Schools:
  • MD, Emory University School of Medicine (1996)
Graduate Schools:
  • MBA, University of Chicago (1991)
Undergraduate Schools:
  • BS, Millsaps College (MS) (1985)
Internships:
  • University of Texas Southwestern Medical School Program (1997)
Residency Programs:
  • University of Texas Southwestern Medical School Program, Chief Resident, Internal Medicine (1999)
Fellowships:
  • Johns Hopkins University School of Medicine Program, Medical Oncology (2002)
Languages: English
Department: Medicine-Medical Oncology
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