Christine Chan, MD
Associate Professor, Pediatrics-Endocrinology

Photo
Medical School:
  • MD, University of California, Irvine, School of Medicine (2006)
Undergraduate School:
  • BA, University of California–Berkeley (CA) (2002)
Residency:
  • Kaiser Permanente Medical Group (Northern California/Oakland) Program, Pediatrics (2009)
Fellowships:
  • University of Colorado (Children's Hospital Colorado) Program, Pediatric Endocrinology (2012)
Languages: English
Department: Pediatrics-Endocrinology

Teaching

  • Director of Pediatric Endocrine Electives (2012)
    School of Medicine, Pediatrics
    Pediatric Endocrinology

Publications

  • Chan CL, Steck AK, Severn C, Pyle L, Rewers M, Zeitler PS. Lessons From Continuous Glucose Monitoring in Youth With Pre-Type 1 Diabetes, Obesity, and Cystic Fibrosis. Diabetes Care. 2020 Jan 14. [Epub ahead of print] PubMed PMID: 31937609
  • Kelsey MM, Zeitler PS, Drews K, Chan CL. Normal Hemoglobin A1c Variability in Early Adolescence: Adult Criteria for Prediabetes Should Be Applied with Caution. J Pediatr. 2020 Jan;216:232-235. PubMed PMID: 31405525
  • Tommerdahl KL, Brinton JT, Vigers T, Cree-Green M, Zeitler PS, Nadeau KJ, Chan CL. Delayed glucose peak and elevated 1-hour glucose on the oral glucose tolerance test identify youth with cystic fibrosis with lower oral disposition index. J Cyst Fibros. 2020 Sep 11;:2111. [Epub ahead of print] PubMed PMID: 32928701
  • Chan CL. Cystic fibrosis related diabetes: Revisiting the OGTT and alternate screening tests. J Cyst Fibros. 2020 Sep;19(5):671-672. PubMed PMID: 32713805
  • Arslanian S, El Ghormli L, Haymond MH, Chan CL, Chernausek SD, Gandica RG, Gubitosi-Klug R, Levitsky LL, Siska M, Willi SM. Beta cell function and insulin sensitivity in obese youth with maturity onset diabetes of youth mutations vs type 2 diabetes in TODAY: Longitudinal observations and glycemic failure. Pediatr Diabetes. 2020 Jun;21(4):575-585. PubMed PMID: 32064729
  • Chan CL, Steck AK, Severn C, Pyle L, Rewers M, Zeitler PS. Lessons From Continuous Glucose Monitoring in Youth With Pre-Type 1 Diabetes, Obesity, and Cystic Fibrosis. Diabetes Care. 2020 Mar;43(3):e35-e37. PubMed PMID: 31937609
  • Li A, Vigers T, Pyle L, Zemanick E, Nadeau K, Sagel SD, Chan CL. Continuous glucose monitoring in youth with cystic fibrosis treated with lumacaftor-ivacaftor. J Cyst Fibros. 2019 Jan;18(1):144-149. PubMed PMID: 30104123
  • Ode KL, Chan CL, Granandos A, Putman M, Moheet A. Endocrine Complications of Cystic Fibrosis: A Multisystem Disease of the Endocrine Organs. Semin Respir Crit Care Med. 2019 Dec;40(6):810-824. PubMed PMID: 31679155
  • Weinstock RS, Braffett BH, McGuigan P, Larkin ME, Grover NB, Walders-Abramson N, Laffel LM, Chan CL, Chang N, Schwartzman BE, Barajas RA, Celona-Jacobs N, Haymond MW. Self-Monitoring of Blood Glucose in Youth-Onset Type 2 Diabetes: Results From the TODAY Study. Diabetes Care. 2019 May;42(5):903-909. PubMed PMID: 30833375
  • Tommerdahl KL, Brinton JT, Vigers T, Nadeau KJ, Zeitler PS, Chan CL. Screening for cystic fibrosis-related diabetes and prediabetes: Evaluating 1,5-anhydroglucitol, fructosamine, glycated albumin, and hemoglobin A1c. Pediatr Diabetes. 2019 Dec;20(8):1080-1086. PubMed PMID: 31469470
  • Ode KL, Chan CL, Granados A, Moheet A, Moran A, Brennan AL. Cystic fibrosis related diabetes: Medical management. J Cyst Fibros. 2019 Oct;18 Suppl 2:S10-S18. PubMed PMID: 31679720
  • Moheet A, Chan CL, Granados A, Ode KL, Moran A, Battezzati A. Hypoglycemia in cystic fibrosis: Prevalence, impact and treatment. J Cyst Fibros. 2019 Oct;18 Suppl 2:S19-S24. PubMed PMID: 31679723
  • Chan CL, Ode KL, Granados A, Moheet A, Moran A, Hameed S. Continuous glucose monitoring in cystic fibrosis - A practical guide. J Cyst Fibros. 2019 Oct;18 Suppl 2:S25-S31. PubMed PMID: 31679725
  • Granados A, Chan CL, Ode KL, Moheet A, Moran A, Holl R. Cystic fibrosis related diabetes: Pathophysiology, screening and diagnosis. J Cyst Fibros. 2019 Oct;18 Suppl 2:S3-S9. PubMed PMID: 31679726
  • Vigers T, Chan CL, Snell-Bergeon J, Bjornstad P, Zeitler PS, Forlenza G, Pyle L. cgmanalysis: An R package for descriptive analysis of continuous glucose monitor data. PLoS One. 2019;14(10):e0216851. PubMed PMID: 31603912
  • Arslanian S, El Ghormli L, Young Kim J, Bacha F, Chan C, Ismail HM, Levitt Katz LE, Levitsky L, Tryggestad JB, White NH. The Shape of the Glucose Response Curve During an Oral Glucose Tolerance Test: Forerunner of Heightened Glycemic Failure Rates and Accelerated Decline in ß-Cell Function in TODAY. Diabetes Care. 2019 Jan;42(1):164-172. PubMed PMID: 30455329
  • Li A, Vigers T, Pyle L, Zemanick E, Nadeau K, Sagel SD, Chan CL. Continuous glucose monitoring in youth with cystic fibrosis treated with lumacaftor-ivacaftor. J Cyst Fibros. 2019 Jan;18(1):144-149. PubMed PMID: 30104123
  • Arslanian S, El Ghormli L, Kim JY, Bacha F, Chan C, Ismail HM, Levitt Katz LE, Levitsky L, Tryggestad JB, White NH. The Shape of the Glucose Response Curve During an Oral Glucose Tolerance Test: Forerunner of Heightened Glycemic Failure Rates and Accelerated Decline in ß-Cell Function in TODAY. Diabetes Care. 2018 Nov 19. [Epub ahead of print] PubMed PMID: 30455329
  • Simon SL, Vigers T, Campbell K, Pyle L, Branscomb R, Nadeau KJ, Chan CL. Reduced insulin sensitivity is correlated with impaired sleep in adolescents with cystic fibrosis. Pediatr Diabetes. 2018 Nov;19(7):1183-1190. PubMed PMID: 30022572
  • Chan CL, Vigers T, Pyle L, Zeitler PS, Sagel SD, Nadeau KJ. Continuous glucose monitoring abnormalities in cystic fibrosis youth correlate with pulmonary function decline. J Cyst Fibros. 2018 Nov;17(6):783-790. PubMed PMID: 29580828
  • Chan CL, Hope E, Thurston J, Vigers T, Pyle L, Zeitler PS, Nadeau KJ. Hemoglobin A(1c) Accurately Predicts Continuous Glucose Monitoring-Derived Average Glucose in Youth and Young Adults With Cystic Fibrosis. Diabetes Care. 2018 Jul;41(7):1406-1413. PubMed PMID: 29674323
  • Cree-Green M, Xie D, Rahat H, Garcia-Reyes Y, Bergman BC, Scherzinger A, Diniz Behn C, Chan CL, Kelsey MM, Pyle L, Nadeau KJ. Oral Glucose Tolerance Test Glucose Peak Time Is Most Predictive of Prediabetes and Hepatic Steatosis in Obese Girls. J Endocr Soc. 2018 Jun 1;2(6):547-562. PubMed PMID: 29942919
  • Chan CL. Use of Continuous Glucose Monitoring in Youth-Onset Type 2 Diabetes. Curr Diab Rep. 2017 Sep;17(9):66. PubMed PMID: 28726154
  • McCandless SE, Yanovski JA, Miller J, Fu C, Bird LM, Salehi P, Chan CL, Stafford D, Abuzzahab MJ, Viskochil D, Barlow SE, Angulo M, Myers SE, Whitman BY, Styne D, Roof E, Dykens EM, Scheimann AO, Malloy J, Zhuang D, Taylor K, Hughes TE, Kim DD, Butler MG. Effects of MetAP2 inhibition on hyperphagia and body weight in Prader-Willi syndrome: A randomized, double-blind, placebo-controlled trial. Diabetes Obes Metab. 2017 Dec;19(12):1751-1761. PubMed PMID: 28556449
  • Chan CL, Pyle L, Kelsey MM, Newnes L, Baumgartner A, Zeitler PS, Nadeau KJ. Alternate glycemic markers reflect glycemic variability in continuous glucose monitoring in youth with prediabetes and type 2 diabetes. Pediatr Diabetes. 2017 Nov;18(7):629-636. PubMed PMID: 27873436
  • Chan CL, Pyle L, Morehead R, Baumgartner A, Cree-Green M, Nadeau KJ. The role of glycemia in insulin resistance in youth with type 1 and type 2 diabetes. Pediatr Diabetes. 2017 Sep;18(6):470-477. PubMed PMID: 27503277
  • Chan CL, Pyle L, Kelsey M, Newnes L, Zeitler PS, Nadeau KJ. Screening for type 2 diabetes and prediabetes in obese youth: evaluating alternate markers of glycemia - 1,5-anhydroglucitol, fructosamine, and glycated albumin. Pediatr Diabetes. 2016 May;17(3):206-11. PubMed PMID: 25652226
  • Chan CL, Pyle L, Kelsey MM, Newnes L, Baumgartner A, Zeitler PS, Nadeau KJ. Alternate glycemic markers reflect glycemic variability in continuous glucose monitoring in youth with prediabetes and type 2 diabetes. Pediatr Diabetes. 2016 Nov 22. [Epub ahead of print] PubMed PMID: 27873436
  • Chan CL, Pyle L, Morehead R, Baumgartner A, Cree-Green M, Nadeau KJ. The role of glycemia in insulin resistance in youth with type 1 and type 2 diabetes. Pediatr Diabetes. 2016 Aug 9. [Epub ahead of print] PubMed PMID: 27503277
  • Chan CL, Pyle L, Kelsey M, Newnes L, Zeitler PS, Nadeau KJ. Screening for type 2 diabetes and prediabetes in obese youth: evaluating alternate markers of glycemia - 1,5-anhydroglucitol, fructosamine, and glycated albumin. Pediatr Diabetes. 2015 Feb 5. [Epub ahead of print] PubMed PMID: 25652226
  • Chan CL, Pyle L, Newnes L, Nadeau KJ, Zeitler PS, Kelsey MM. Continuous glucose monitoring and its relationship to hemoglobin A1c and oral glucose tolerance testing in obese and prediabetic youth. J Clin Endocrinol Metab. 2015 Mar;100(3):902-10. PubMed PMID: 25532041
  • Chan CL, Taki I, Dong F, Hoffman M, Norris JM, Klingensmith G, Rewers MJ, Steck AK. Comparison of Metabolic Outcomes in Children Diagnosed with Type 1 Diabetes Through Research Screening (Diabetes Autoimmunity Study in the Young [DAISY]) Versus in the Community. Diabetes Technol Ther. 2015 Sep;17(9):649-56. PubMed PMID: 26317880
  • Chan CL, Pyle L, Newnes L, Nadeau KJ, Zeitler PS, Kelsey MM. Continuous Glucose Monitoring and its Relationship to Hemoglobin A1c and Oral Glucose Tolerance Testing in Obese and Prediabetic Youth. J Clin Endocrinol Metab. 2014 Dec 22;:jc20143612. [Epub ahead of print] PubMed PMID: 25532041
  • Chan CL, McFann K, Newnes L, Nadeau KJ, Zeitler PS, Kelsey M. Hemoglobin A1c assay variations and implications for diabetes screening in obese youth. Pediatr Diabetes. 2014 Dec;15(8):557-63. PubMed PMID: 24636682
  • Chan CL, McFann K, Taylor L, Wright D, Zeitler PS, Barker JM. Congenital adrenal hyperplasia and the second newborn screen. J Pediatr. 2013 Jul;163(1):109-13.e1. PubMed PMID: 23414665
  • Love-Osborne KA, Sheeder J, Svircev A, Chan C, Zeitler P, Nadeau KJ. Use of glycosylated hemoglobin increases diabetes screening for at-risk adolescents in primary care settings. Pediatr Diabetes. 2013 Nov;14(7):512-8. PubMed PMID: 23659706
View All (36 Total) View Less

Professional Memberships

  • The Endocrine Society (ENDO), Member
  • Pediatric Endocrine Society (LWPES), Member
  • American Diabetes Association (ADA), Member
  • American Academy of Pediatrics (AAP), Member

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Children's Colorado Outpatient and Urgent Care at Uptown
1830 Franklin St
Denver, CO 80218
720-777-1360

Barbara Davis Center for Childhood Diabetes - Specialty Clinic
1775 Aurora Ct
Aurora, CO 80045
303-724-2323

Hospital Affiliation
  • Children's Hospital Colorado
  • University of Colorado Hospital
Center Affiliations

Specialty Information

Specialties
  • Pediatrics, Board Certification (2009)
  • Pediatric Endocrinology, Board Certification (2013)

General Information

Medical Schools:
  • MD, University of California, Irvine, School of Medicine (2006)
Undergraduate Schools:
  • BA, University of California–Berkeley (CA) (2002)
Residency Programs:
  • Kaiser Permanente Medical Group (Northern California/Oakland) Program, Pediatrics (2009)
Fellowships:
  • University of Colorado (Children's Hospital Colorado) Program, Pediatric Endocrinology (2012)
Languages: English
Department: Pediatrics-Endocrinology
;