Csaba Galambos, MD, PhD
Professor, Pathology

Photo
Graduate Schools :
  • PhD, Semmelweis University (2008)
  • MD, University of Pecs (1992)
Residency:
  • Saint Louis University School of Medicine Program, Pathology (2002)
Fellowships:
  • Children's Hospital (Boston) Program, Pediatric Pathology (2003)
  • University of Washington Program, Bioengineering (1997)
Languages: English, Hungarian
Department: Pathology

Professional Titles

  • Professor of Pathology

Recognition & Awards

  • Enid Gilbert Barness Prize, Society for Pediatric Pathology (2017)
  • Letter of Recognition for Excellence in Teaching, Society for Pediatric Pathology Educational Committee (2017)
  • Harry B. Neustein Memorial Award, Society for Pediatric Pathology (2013)
  • Perinatal Pathology Award, Society for Pediatric Pathology/ Perinatal Section (2013)
  • Teaching Faculty of the Year Nominee, Department of Pathology, UPMC (2011)
  • James McAdams Short-Term Study Award, Society for Pediatric Pathology (2009)
  • Chief Pediatric PathologyFellow, Boston Children's Hospital/Harvard Medical School (2003)
  • The Lotte Strauss Prize, Society for Pediatric Pathology (2003)
  • Roland Quest Memorial Award for Outstanding Service, Department of Pathology, St. Louis University (2002)
  • Pathologist-in-Training Award, Society of Ultrastructural Pathology (2001)
  • Travel Award, Society of Ultrastructural Pathology (2001)
  • Gordon Vawter Pathologist-in-Training Award, Society of Pediatric Pathology (2001)
  • Paul E. Strandjord Young Investigator Award, Academy of Clinical Laboratory Physicians and Scientists (2000)

Publications

  • Norvik C, Westöö CK, Peruzzi N, Lovric G, van der Have O, Mokso R, Jeremiasen I, Brunnström H, Galambos C, Bech M, Tran-Lundmark K. Synchrotron-based phase-contrast micro-CT as a tool for understanding pulmonary vascular pathobiology and the 3-D microanatomy of alveolar capillary dysplasia. Am J Physiol Lung Cell Mol Physiol. 2020 Jan 1;318(1):L65-L75. PubMed PMID: 31596108
  • Galambos C, Wartchow E, Weinman JP, Abman SH. Pulmonary interstitial glycogenosis cells express mesenchymal stem cell markers. Eur Respir J. 2020 Oct;56(4). PubMed PMID: 32430418
  • Bush D, Galambos C, Dunbar Ivy D. Pulmonary hypertension in children with Down syndrome. Pediatr Pulmonol. 2020 Feb 12. [Epub ahead of print] PubMed PMID: 32049444
  • Dewberry LC, Trecartin A, Galambos C, Hilton SA, Dannull K, Zaretsky MV, Behrendt N, Galan HL, Marwan AI, Liechty KW. A congenital cystic pulmonary airway malformation occurring together with both an extralobar pulmonary sequestration and an esophageal duplication cyst. Clin Case Rep. 2020 Jan;8(1):18-23. PubMed PMID: 31998479
  • Birjiniuk A, Glinton KE, Villafranco N, Boyer S, Laufman J, Mizerik E, Scott D, Elsea SH, Galambos C, Varghese NP, Scaglia F. Multiple mitochondrial dysfunctions syndrome 1: An unusual cause of developmental pulmonary hypertension. Am J Med Genet A. 2020 Apr;182(4):755-761. PubMed PMID: 31970900
  • Norvik C, Westöö CK, Peruzzi N, Lovric G, van der Have O, Mokso R, Jeremiasen I, Brunnström H, Galambos C, Bech M, Tran-Lundmark K. Synchrotron-based phase-contrast micro-CT as a tool for understanding pulmonary vascular pathobiology and the 3-D microanatomy of alveolar capillary dysplasia. Am J Physiol Lung Cell Mol Physiol. 2020 Jan 1;318(1):L65-L75. PubMed PMID: 31596108
  • Johnson Kameny R, Datar SA, Boehme JB, Morris C, Zhu T, Goudy BD, Johnson EG, Galambos C, Raff GW, Sun X, Wang T, Chiacchia SR, Lu Q, Black SM, Maltepe E, Fineman JR. Ovine Models of Congenital Heart Disease and the Consequences of Hemodynamic Alterations for Pulmonary Artery Remodeling. Am J Respir Cell Mol Biol. 2019 Jan 8. [Epub ahead of print] PubMed PMID: 30620615
  • Koo J, Knight-Perry J, Galambos C, Browne LP, Cost CR. Pediatric Metastatic Cardiac Angiosarcoma Successfully Treated With Multimodal Therapy: Case Report and Review of Literature. J Pediatr Hematol Oncol. 2019 Nov 12. [Epub ahead of print] PubMed PMID: 31725539
  • Bush D, Wolter-Warmerdam K, Wagner BD, Galambos C, Ivy DD, Abman S, McMorrow D, Hickey F. EXPRESS: Angiogenic Profile Identifies Pulmonary Hypertension in Children with Down Syndrome. Pulm Circ. 2019 Jul 11;:2045894019866549. [Epub ahead of print] PubMed PMID: 31293212
  • Galambos C, Mullen MP, Shieh JT, Schwerk N, Kielt MJ, Ullmann N, Boldrini R, Stucin-Gantar I, Haass C, Bansal M, Agrawal PB, Johnson J, Peca D, Surace C, Cutrera R, Pauciulo MW, Nichols WC, Griese M, Ivy D, Abman SH, Austin ED, Danhaive O. Phenotype characterisation of TBX4 mutation and deletion carriers with neonatal and paediatric pulmonary hypertension. Eur Respir J. 2019 Aug;54(2). PubMed PMID: 31151956
  • Fernandez IZ, Baxter RM, Garcia-Perez JE, Vendrame E, Ranganath T, Kong DS, Lundquist K, Nguyen T, Ogolla S, Black J, Galambos C, Gumbart JC, Dawany N, Kelsen JR, de Zoeten EF, Quinones R, Eissa H, Verneris MR, Sullivan KE, Rochford R, Blish CA, Kedl RM, Dutmer CM, Hsieh EWY. Correction: A novel human IL2RB mutation results in T and NK cell-driven immune dysregulation. J Exp Med. 2019 Jun 3;216(6):1465. PubMed PMID: 31088899
  • Fernandez IZ, Baxter RM, Garcia-Perez JE, Vendrame E, Ranganath T, Kong DS, Lundquist K, Nguyen T, Ogolla S, Black J, Galambos C, Gumbart JC, Dawany N, Kelsen JR, de Zoeten EF, Quinones R, Eissa H, Verneris MR, Sullivan KE, Rochford R, Blish CA, Kedl RM, Dutmer CM, Hsieh EWY. A novel human IL2RB mutation results in T and NK cell-driven immune dysregulation. J Exp Med. 2019 Jun 3;216(6):1255-1267. PubMed PMID: 31040184
  • LeMoine BD, Browne LP, Liptzin DR, Deterding RR, Galambos C, Weinman JP. High-resolution computed tomography findings of thyroid transcription factor 1 deficiency (NKX2-1 mutations). Pediatr Radiol. 2019 Jun;49(7):869-875. PubMed PMID: 30927038
  • Ali M, Kowkuntla S, Delloro DJ, Galambos C, Hathi D, Janz S, Shokeen M, Tripathi C, Xu H, Yuk J, Zhan F, Tomasson MH, Bates ML. Chronic intermittent hypoxia enhances disease progression in myeloma-resistant mice. Am J Physiol Regul Integr Comp Physiol. 2019 May 1;316(5):R678-R686. PubMed PMID: 30892915
  • Johnson Kameny R, Datar SA, Boehme JB, Morris C, Zhu T, Goudy BD, Johnson EG, Galambos C, Raff GW, Sun X, Wang T, Chiacchia SR, Lu Q, Black SM, Maltepe E, Fineman JR. Ovine Models of Congenital Heart Disease and the Consequences of Hemodynamic Alterations for Pulmonary Artery Remodeling. Am J Respir Cell Mol Biol. 2019 May;60(5):503-514. PubMed PMID: 30620615
  • Gilani A, Black JO, Weinman JP, Galambos C. Sudden Death due to Complete Airway Obstruction by Bronchial Casts. Am J Respir Crit Care Med. 2019 Feb 1;199(3):380. PubMed PMID: 30252500
  • Bush D, Sremba L, Lomax K, Lipsett J, Ketteridge D, Bratkovic D, Enchautegui-Colon Y, Weisfeld-Adams J, Galambos C, Lummus S, Wartchow E, Weinman J, Liptzin DR, Baker P 2nd. Neonatal Onset Interstitial Lung Disease as a Primary Presenting Manifestation of Mucopolysaccharidosis Type I. JIMD Rep. 2019;43:71-77. PubMed PMID: 29654546
  • McGraw MD, Houser GH, Galambos C, Wartchow EP, Stillwell PC, Weinman JP. Marijuana medusa: The many pulmonary faces of marijuana inhalation in adolescent males. Pediatr Pulmonol. 2018 Dec;53(12):1619-1626. PubMed PMID: 30353708
  • Gilani A, Black JO, Weinman JP, Galambos C. Sudden Death Due to Complete Airway Obstruction by Bronchial Casts. Am J Respir Crit Care Med. 2018 Sep 25. [Epub ahead of print] PubMed PMID: 30252500
  • Adang LA, Frank DB, Gilani A, Takanohashi A, Ulrick N, Collins A, Cross Z, Galambos C, Helman G, Kanaan U, Keller S, Simon D, Sherbini O, Hanna BD, Vanderver AL. Aicardi goutières syndrome is associated with pulmonary hypertension. Mol Genet Metab. 2018 Dec;125(4):351-358. PubMed PMID: 30219631
  • Galambos C, Bates ML, Bush D, Abman SH. Prominent Bronchopulmonary Vascular Anastomoses in Fatal Childhood Asthma. Ann Am Thorac Soc. 2018 Nov;15(11):1359-1362. PubMed PMID: 30079749
  • Bush D, Galambos C, Ivy DD, Abman SH, Wolter-Warmerdam K, Hickey F. Clinical Characteristics and Risk Factors for Developing Pulmonary Hypertension in Children with Down Syndrome. J Pediatr. 2018 Nov;202:212-219.e2. PubMed PMID: 30025669
  • Liptzin DR, Baker CD, Darst JR, Weinman JP, Dishop MK, Galambos C, Brinton JT, Deterding RR. Pulmonary interstitial glycogenosis: Diagnostic evaluation and clinical course. Pediatr Pulmonol. 2018 Dec;53(12):1651-1658. PubMed PMID: 30019520
  • Weinman JP, White CJ, Liptzin DR, Deterding RR, Galambos C, Browne LP. High-resolution CT findings of pulmonary interstitial glycogenosis. Pediatr Radiol. 2018 Aug;48(8):1066-1072. PubMed PMID: 29687227
  • Bates ML, Anagnostopoulos PV, Nygard C, Torgeson J, Reichert J, Galambos C, Eldridge MW, Lamers LJ. Consequences of an early catheter-based intervention on pulmonary artery growth and right ventricular myocardial function in a pig model of pulmonary artery stenosis. Catheter Cardiovasc Interv. 2018 Mar 30. [Epub ahead of print] PubMed PMID: 29602248
  • Bloom JL, Lin C, Imundo L, Guthery S, Stepenaskie S, Galambos C, Lowichik A, Bohnsack JF. H syndrome: 5 new cases from the United States with novel features and responses to therapy. Pediatr Rheumatol Online J. 2017 Oct 17;15(1):76. PubMed PMID: 29041934
  • Bush D, Deterding R, Weinman J, Galambos C. Hypoxemia in Lipoid Pneumonia: Role of Intrapulmonary Bronchopulmonary Anastomoses. Am J Respir Crit Care Med. 2017 Jun 1;195(11):1531-1532. PubMed PMID: 28534692
  • Zhelnin KE, Gebhard GM, Mirsky DM, Oliver SC, Lovell MA, Galambos C, Crombleholme TM, McCourt EA. Pediatric Intraocular Immature Teratoma Associated With Sacrococcygeal Teratoma. Pediatr Dev Pathol. 2017 Jun;20(3):240-244. PubMed PMID: 28521629
  • McGraw MD, Galambos C, Stillwell PC. Uremic pleuritis: A case report and review of recurrent exudative pleural effusions in children. Pediatr Pulmonol. 2017 Sep;52(9):E52-E54. PubMed PMID: 28440918
  • Castro EC, Sen P, Parks WT, Langston C, Galambos C. The Role of Serotonin Transporter in Human Lung Development and in Neonatal Lung Disorders. Can Respir J. 2017;2017:9064046. PubMed PMID: 28316463
  • Woulfe KC, Siomos AK, Nguyen H, SooHoo M, Galambos C, Stauffer BL, Sucharov C, Miyamoto S. Fibrosis and Fibrotic Gene Expression in Pediatric and Adult Patients With Idiopathic Dilated Cardiomyopathy. J Card Fail. 2017 Apr;23(4):314-324. PubMed PMID: 27890770
  • Siegele B, Roberts J, Black JO, Rudzinski E, Vargas SO, Galambos C. DUX4 Immunohistochemistry Is a Highly Sensitive and Specific Marker for CIC-DUX4 Fusion-positive Round Cell Tumor. Am J Surg Pathol. 2017 Mar;41(3):423-429. PubMed PMID: 27879517
  • Bush D, Abman SH, Galambos C. Prominent Intrapulmonary Bronchopulmonary Anastomoses and Abnormal Lung Development in Infants and Children with Down Syndrome. J Pediatr. 2017 Jan;180:156-162.e1. PubMed PMID: 27666181
  • El-Gohary Y, Wiersch J, Tulachan S, Xiao X, Guo P, Rymer C, Fischbach S, Prasadan K, Shiota C, Gaffar I, Song Z, Galambos C, Esni F, Gittes GK. Intraislet Pancreatic Ducts Can Give Rise to Insulin-Positive Cells. Endocrinology. 2016 Jan;157(1):166-75. PubMed PMID: 26505114
  • Galambos C, Sims-Lucas S, Abman SH, Cool CD. Intrapulmonary Bronchopulmonary Anastomoses and Plexiform Lesions in Idiopathic Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2016 Mar 1;193(5):574-6. PubMed PMID: 26930433
  • Zhelnin K, Gebhard G, Mirsky D, Oliver S, Lovell MA, Galambos C, Crombleholme T, McCourt E. Pediatric intraocular immature teratoma associated with sacrococcygeal teratoma: case report and review of the literature. Pediatr Dev Pathol. 2016 Jul 6. [Epub ahead of print] PubMed PMID: 27385488
  • Galambos C, Minic AD, Bush D, Nguyen D, Dodson B, Seedorf G, Abman SH. Increased Lung Expression of Anti-Angiogenic Factors in Down Syndrome: Potential Role in Abnormal Lung Vascular Growth and the Risk for Pulmonary Hypertension. PLoS One. 2016 Aug 3;11(8):e0159005. PubMed PMID: 27487163
  • Siegele B, Roberts J, Black JO, Rudzinski E, Vargas SO, Galambos C. DUX4 Immunohistochemistry is a Highly Sensitive and Specific Marker for CIC-DUX4 Fusion-positive Round Cell Tumor. Am J Surg Pathol. 2016 Nov 22. [Epub ahead of print] PubMed PMID: 27879517
  • Acker SN, Mandell EW, Sims-Lucas S, Gien J, Abman SH, Galambos C. Histologic identification of prominent intrapulmonary anastomotic vessels in severe congenital diaphragmatic hernia. J Pediatr. 2015 Jan;166(1):178-83. PubMed PMID: 25306189
  • Galambos C, Sims-Lucas S, Ali N, Gien J, Dishop MK, Abman SH. Intrapulmonary vascular shunt pathways in alveolar capillary dysplasia with misalignment of pulmonary veins. Thorax. 2015 Jan;70(1):84-5. PubMed PMID: 25052575
  • Liptzin DR, Watson AM, Murphy E, Kroehl ME, Dishop MK, Galambos C, Evans CM, Schwarz MI, Deterding RR, Schwartz DA. MUC5B expression and location in surfactant protein C mutations in children. Pediatr Pulmonol. 2015 Apr 7. [Epub ahead of print] PubMed PMID: 25858779
  • Fan LL, Dishop MK, Galambos C, Askin FB, White FV, Langston C, Liptzin DR, Kroehl ME, Deutsch GH, Young LR, Kurland G, Hagood J, Dell S, Trapnell BC, Deterding RR. Diffuse Lung Disease in Biopsied Children 2 to 18 Years of Age. Application of the chILD Classification Scheme. Ann Am Thorac Soc. 2015 Oct;12(10):1498-505. PubMed PMID: 26291470
  • Ali N, Abman SH, Galambos C. Histologic Evidence of Intrapulmonary Bronchopulmonary Anastomotic Pathways in Neonates with Meconium Aspiration Syndrome. J Pediatr. 2015 Dec;167(6):1445-7. PubMed PMID: 26421487
  • El-Gohary Y, Wiersch J, Tulachan S, Xiao X, Guo P, Rymer C, Fischbach S, Prasadan K, Shiota C, Gaffar I, Song Z, Galambos C, Esni F, Gittes GK. Intra-Islet Pancreatic Ducts Can Give Rise to Insulin-Positive Cells. Endocrinology. 2015 Oct 27;:en20151175. [Epub ahead of print] PubMed PMID: 26505114
  • Abman SH, Baker C, Gien J, Mourani P, Galambos C. The Robyn Barst Memorial Lecture: Differences between the fetal, newborn, and adult pulmonary circulations: relevance for age-specific therapies (2013 Grover Conference series). Pulm Circ. 2014 Sep;4(3):424-40. PubMed PMID: 25621156
  • Dodson RB, Morgan MR, Galambos C, Hunter KS, Abman SH. Chronic intrauterine pulmonary hypertension increases main pulmonary artery stiffness and adventitial remodeling in fetal sheep. Am J Physiol Lung Cell Mol Physiol. 2014 Dec 1;307(11):L822-8. PubMed PMID: 25326575
  • Castro EC, Parks WT, Galambos C. The ontogeny of human pulmonary angiotensin-converting enzyme and its aberrant expression may contribute to the pathobiology of bronchopulmonary dysplasia (BPD). Pediatr Pulmonol. 2014 Oct;49(10):985-90. PubMed PMID: 24574430
  • Yannam GR, Han B, Setoyama K, Yamamoto T, Ito R, Brooks JM, Guzman-Lepe J, Galambos C, Fong JV, Deutsch M, Quader MA, Yamanouchi K, Kabarriti R, Mehta K, Soto-Gutierrez A, Roy-Chowdhury J, Locker J, Abe M, Enke CA, Baranowska-Kortylewicz J, Solberg TD, Guha C, Fox IJ. A nonhuman primate model of human radiation-induced venocclusive liver disease and hepatocyte injury. Int J Radiat Oncol Biol Phys. 2014 Feb 1;88(2):404-11. PubMed PMID: 24315566
  • Galambos C, Sims-Lucas S, Abman SH. Three-dimensional reconstruction identifies misaligned pulmonary veins as intrapulmonary shunt vessels in alveolar capillary dysplasia. J Pediatr. 2014 Jan;164(1):192-5. PubMed PMID: 24079727
  • Michaelis KA, Agboke F, Liu T, Han K, Muthu M, Galambos C, Yang G, Dennery PA, Wright CJ. I?Bß-mediated NF-?B activation confers protection against hyperoxic lung injury. Am J Respir Cell Mol Biol. 2014 Feb;50(2):429-38. PubMed PMID: 24066808
  • Castro EC, Parks WT, Galambos C. The ontogeny of human pulmonary angiotensin-converting enzyme and its aberrant expression may contribute to the pathobiology of bronchopulmonary dysplasia (BPD). Pediatr Pulmonol. 2013 Oct 28. [Epub ahead of print] PubMed PMID: 24574430
  • Nguyen L, Riley MM, Sen P, Galambos C. Alveolar capillary dysplasia with misalignment of pulmonary veins with a wide spectrum of extrapulmonary manifestations. Pathol Int. 2013 Oct;63(10):519-21. PubMed PMID: 24147432
  • Galambos C, Sims-Lucas S, Abman SH. Histologic evidence of intrapulmonary anastomoses by three-dimensional reconstruction in severe bronchopulmonary dysplasia. Ann Am Thorac Soc. 2013 Oct;10(5):474-81. PubMed PMID: 23987309
  • Sen P, Yang Y, Navarro C, Silva I, Szafranski P, Kolodziejska KE, Dharmadhikari AV, Mostafa H, Kozakewich H, Kearney D, Cahill JB, Whitt M, Bilic M, Margraf L, Charles A, Goldblatt J, Gibson K, Lantz PE, Garvin AJ, Petty J, Kiblawi Z, Zuppan C, McConkie-Rosell A, McDonald MT, Peterson-Carmichael SL, Gaede JT, Shivanna B, Schady D, Friedlich PS, Hays SR, Palafoll IV, Siebers-Renelt U, Bohring A, Finn LS, Siebert JR, Galambos C, Nguyen L, Riley M, Chassaing N, Vigouroux A, Rocha G, Fernandes S, Brumbaugh J, Roberts K, Ho-Ming L, Lo IF, Lam S, Gerychova R, Jezova M, Valaskova I, Fellmann F, Afshar K, Giannoni E, Muhlethaler V, Liang J, Beckmann JS, Lioy J, Deshmukh H, Srinivasan L, Swarr DT, Sloman M, Shaw-Smith C, van Loon RL, Hagman C, Sznajer Y, Barrea C, Galant C, Detaille T, Wambach JA, Cole FS, Hamvas A, Prince LS, Diderich KE, Brooks AS, Verdijk RM, Ravindranathan H, Sugo E, Mowat D, Baker ML, Langston C, Welty S, Stankiewicz P. Novel FOXF1 mutations in sporadic and familial cases of alveolar capillary dysplasia with misaligned pulmonary veins imply a role for its DNA binding domain. Hum Mutat. 2013 Jun;34(6):801-11. PubMed PMID: 23505205
  • Xu Y, Galambos C, Reyes-Múgica M, Miller SA, Zeevi A, Webber SA, Feingold B. Utility of C4d immunostaining in the first year after pediatric and young adult heart transplantation. J Heart Lung Transplant. 2013 Jan;32(1):92-7. PubMed PMID: 23260709
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Professional Memberships

  • Society for Pediatric Pathology (SPP), Member
  • United States and Canadian Academy of Pathology (USCAP), Member
  • The International Society for the Study of Vascular Anomalies (ISSVA), Member
  • Pulmonary Pathology Society (PPS), Member
  • North American Vascular Biology Organization (NAVBO), Member
  • American Thoracic Society, Member
  • Children Interstitial Lung Disease (ChILD) Research Cooperative, Advanced case reviewer

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation
  • Children's Hospital Colorado

Specialty Information

Specialties
  • Anatomic and Clinical, Board Certification (2003)
  • Pediatric Pathology, Board Certification (2003)
  • Mentoring Training (CO-Mentor) Program, Certificate (2017)
  • Physician Leadership & Management Mini-MBA, Certificate (2011)
Care Philosophy
I am dedicated to providing the highest quality, professional, and ethical care to all patients. I am a physician-scientist committed to a combined academic track of research and clinical service. I carry out my clinical responsibilities as a pediatric pathologist at Children’s Hospital Colorado, where I provide diagnostic expertise in pediatric surgical and autopsy pathology with subspecialty expertise in pediatric lung disease. I provide comprehensive diagnostic service for infants and children with pulmonary disease by coordinating multidisciplinary approach through The Breathing Institute, Department of Pediatric Surgery and Colorado Institute for Maternal and Fetal Health. I have a career-long passion for understanding the mechanisms of lung vascular development and related disorders in order to develop novel strategies that could lead to earlier diagnoses, prevention, and potential cures for infants and children with pulmonary vascular disease. I serve as a nationally and internationally recognized pediatric pulmonary pathology case consultant.

General Information

Graduate Schools:
  • PhD, Semmelweis University (2008)
  • MD, University of Pecs (1992)
Residency Programs:
  • Saint Louis University School of Medicine Program, Pathology (2002)
Fellowships:
  • Children's Hospital (Boston) Program, Pediatric Pathology (2003)
  • University of Washington Program, Bioengineering (1997)
Languages: English, Hungarian
Department: Pathology
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