Michael Weyant, MD
Professor, Surgery-Cardiothoracic

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Medical School:
  • MD, Mount Sinai School of Medicine (1996)
Undergraduate School:
  • BS, Syracuse University (NY) (1992)
Internship:
  • New York Presbyterian Hospital (Cornell Campus) Program (1997)
Residency:
  • New York Presbyterian Hospital (Cornell Campus) Program, Surgery (2003)
Fellowships:
  • Memorial Sloan-Kettering Cancer Center/New York Presbyterian Hospital (Cornell Campus) Program, Thoracic and Cardiac (2005)
Languages: English
Department: Surgery-Cardiothoracic

Recognition & Awards

  • Dwight McGoon Award, American Association for Thoracic Surgery (2010)
  • Golfers' Against Cancer Award, Golfers' Against Cancer (2009)
  • First Place in Poster Presentation - General Thoracic Surgery, Society of Thoracic Surgeons (2008)
  • University of Colorado Medical Student Golden Apple Teacher of the Year Award, University of Colorado School of Medicine (2008)
  • 2007 Shumway Award, Western Thoracic Surgical Association (2007)
  • C.C.K.W. Gary L. and Thelissa Zollinger Early Detection of Lung Cancer Endowment, Gary and Thelissa Zollinger (2007)

Teaching

  • Associate Professor (2010)
    School of Medicine, Surgery
  • Assistant Professor (2005)
    School of Medicine, Surgery
  • Professor of Surgery (2017)
    School of Medicine, Surgery

Publications

  • Bhagat R, Bronsert MR, Henderson WG, Scott CD, Weyant MJ, Mitchell JD, Fullerton DA, Meguid RA. Analysis of Discharge Destination After Open Versus Minimally Invasive Surgery for Lung Cancer. Ann Thorac Surg. 2020 Feb;109(2):375-382. PubMed PMID: 31580860
  • Halpern AL, Boshier PR, White AM, Houk AK, Helmkamp L, Mitchell JD, Meguid RA, Low DE, Fullerton DA, Weyant MJ. A Comparison of Frailty Measures at Listing to Predict Outcomes After Lung Transplantation. Ann Thorac Surg. 2020 Jan;109(1):233-240. PubMed PMID: 31479636
  • Halpern AL, Kohtz PD, Rove JY, Ao L, Meng X, Fullerton DA, Weyant MJ. Inhibition of secretory phospholipase A2 IIa attenuates prostaglandin E2-induced invasiveness in lung adenocarcinoma. Mol Cell Biochem. 2019 Jan 25. [Epub ahead of print] PubMed PMID: 30684134
  • Yamanaka K, Eldeiry M, Aftab M, Ryan TJ, Meng X, Weyant MJ, Fullerton DA, Reece TB. Synergetic Induction of NGF With Diazoxide and Erythropoietin Attenuates Spinal Cord Ischemic Injury. J Surg Res. 2019 Jan;233:124-131. PubMed PMID: 30502238
  • Kohtz PD, Halpern AL, Eldeiry MA, Hazel K, Kalatardi S, Ao L, Meng X, Reece TB, Fullerton DA, Weyant MJ. Toll-Like Receptor-4 Is a Mediator of Proliferation in Esophageal Adenocarcinoma. Ann Thorac Surg. 2019 Jan;107(1):233-241. PubMed PMID: 30292843
  • Jarrett MJ, Yao Q, Venardos N, Weyant MJ, Reece TB, Meng X, Fullerton DA. Simvastatin down-regulates osteogenic response in cultured human aortic valve interstitial cells. J Thorac Cardiovasc Surg. 2019 Oct 31. [Epub ahead of print] PubMed PMID: 31924353
  • Head L, Kiseljak-Vassiliades K, Clark TJ, Somerset H, King J, Raeburn C, Albuja-Cruz M, Weyant M, Cleveland J, Wierman ME, Leong S. Response to Immunotherapy in Combination With Mitotane in Patients With Metastatic Adrenocortical Cancer. J Endocr Soc. 2019 Dec 1;3(12):2295-2304. PubMed PMID: 31745526
  • Halpern AL, Friedman C, Torphy RJ, Al-Musawi MH, Mitchell JD, Scott CD, Meguid RA, McCarter MD, Weyant MJ, Gleisner AL. Conversion to open surgery during minimally invasive esophagectomy portends worse short-term outcomes: an analysis of the National Cancer Database. Surg Endosc. 2019 Oct 7. [Epub ahead of print] PubMed PMID: 31591657
  • Chapman BC, Weyant M, Hilton S, Hosokawa PW, McCarter MD, Gleisner A, Nader ND, Gajdos C. Analysis of the National Cancer Database Esophageal Squamous Cell Carcinoma in the United States. Ann Thorac Surg. 2019 Nov;108(5):1535-1542. PubMed PMID: 31302081
  • Halpern AL, Weyant MJ. Video-Assisted Thoracoscopic Pneumonectomy for Complications of Congenital Pulmonary Venous Stenosis. Ann Thorac Surg. 2019 Dec;108(6):e357-e359. PubMed PMID: 31158352
  • Halpern AL, Kohtz PD, Helmkamp L, Eldeiry M, Hodges MM, Scott CD, Mitchell JD, Aftab M, Pal JD, Cleveland JC, Reece TB, Meguid RA, Fullerton DA, Weyant MJ. Improved Mortality Associated With the Use of Extracorporeal Membrane Oxygenation. Ann Thorac Surg. 2019 Aug;108(2):350-357. PubMed PMID: 31009629
  • Halpern AL, Kohtz PD, Rove JY, Ao L, Meng X, Fullerton DA, Weyant MJ. Inhibition of secretory phospholipase A2 IIa attenuates prostaglandin E2-induced invasiveness in lung adenocarcinoma. Mol Cell Biochem. 2019 Jun;456(1-2):145-156. PubMed PMID: 30684134
  • Yamanaka K, Eldeiry M, Aftab M, Ryan TJ, Meng X, Weyant MJ, Fullerton DA, Reece TB. Synergetic Induction of NGF With Diazoxide and Erythropoietin Attenuates Spinal Cord Ischemic Injury. J Surg Res. 2019 Jan;233:124-131. PubMed PMID: 30502238
  • Yamanaka K, Eldeiry M, Aftab M, Ryan TJ, Roda G, Meng X, Weyant MJ, Cleveland JC Jr, Fullerton DA, Reece TB. Pretreatment With Diazoxide Attenuates Spinal Cord Ischemia-Reperfusion Injury Through Signaling Transducer and Activator of Transcription 3 Pathway. Ann Thorac Surg. 2019 Mar;107(3):733-739. PubMed PMID: 30395862
  • Kohtz PD, Halpern AL, Eldeiry MA, Hazel K, Kalatardi S, Ao L, Meng X, Reece TB, Fullerton DA, Weyant MJ. Toll-Like Receptor-4 Is a Mediator of Proliferation in Esophageal Adenocarcinoma. Ann Thorac Surg. 2019 Jan;107(1):233-241. PubMed PMID: 30292843
  • Yamanaka K, Eldeiry M, Aftab M, Ryan TJ, Roda G, Meng X, Weyant MJ, Cleveland JC Jr, Fullerton DA, Reece TB. Pretreatment with Diazoxide Attenuates Spinal Cord Ischemia-Reperfusion Injury Through STAT3 pathway. Ann Thorac Surg. 2018 Nov 2. [Epub ahead of print] PubMed PMID: 30395862
  • Mulligan MS, Weill D, Davis RD, Christie JD, Farjah F, Singer JP, Hartwig M, Sanchez PG, Kreisel D, Ware LB, Bermudez C, Hachem RR, Weyant MJ, Gries C, Awori Hayanga JW, Griffith BP, Snyder LD, Odim J, Craig JM, Aggarwal NR, Reineck LA. National Heart, Lung, and Blood Institute and American Association for Thoracic Surgery Workshop Report: Identifying collaborative clinical research priorities in lung transplantation. J Thorac Cardiovasc Surg. 2018 Dec;156(6):2355-2365. PubMed PMID: 30244865
  • Yamanaka K, Eldeiry M, Aftab M, Ryan TJ, Mares J, Meng X, Weyant MJ, Cleveland JC Jr, Fullerton DA, Reece TB. Synergistic Reduction of Apoptosis With Diazoxide and Erythropoietin in Spinal Cord Ischemic Injury. Ann Thorac Surg. 2018 Dec;106(6):1751-1758. PubMed PMID: 30193997
  • Venardos N, Deng XS, Yao Q, Weyant MJ, Reece TB, Meng X, Fullerton DA. Simvastatin reduces the TLR4-induced inflammatory response in human aortic valve interstitial cells. J Surg Res. 2018 Oct;230:101-109. PubMed PMID: 30100024
  • Weyant MJ. The optimal sequencing of postoperative chemotherapy and radiation therapy in patients with locally advanced or incompletely resected non-small cell lung cancer. J Thorac Dis. 2018 Jun;10(Suppl 17):S1971-S1973. PubMed PMID: 30023093
  • Yamanaka K, Eldeiry M, Aftab M, Mares J, Ryan TJ, Meng X, Weyant MJ, Cleveland JC Jr, Fullerton DA, Reece TB. Optimized induction of beta common receptor enhances the neuroprotective function of erythropoietin in spinal cord ischemic injury. J Thorac Cardiovasc Surg. 2018 Jun;155(6):2505-2516. PubMed PMID: 29523405
  • Bhagat R, Bronsert MR, Juarez-Colunga E, Weyant MJ, Mitchell JD, Glebova NO, Henderson WG, Fullerton D, Meguid RA. Postoperative Complications Drive Unplanned Readmissions After Esophagectomy for Cancer. Ann Thorac Surg. 2018 May;105(5):1476-1482. PubMed PMID: 29373825
  • Bhagat R, Bronsert MR, Ward AN, Martin J, Juarez-Colunga E, Glebova NO, Henderson WG, Fullerton D, Weyant MJ, Mitchell JD, Meguid RA. National Analysis of Unplanned Readmissions After Thoracoscopic Versus Open Lung Cancer Resection. Ann Thorac Surg. 2017 Dec;104(6):1782-1790. PubMed PMID: 29102302
  • Foley LS, Fullerton DA, Mares J, Sungelo M, Weyant MJ, Cleveland JC Jr, Reece TB. Erythropoietin's Beta Common Receptor Mediates Neuroprotection in Spinal Cord Neurons. Ann Thorac Surg. 2017 Dec;104(6):1909-1914. PubMed PMID: 29100648
  • Tan YB, Mulekar S, Gorodnya O, Weyant MJ, Zamora MR, Simmons JD, Machuka T, Gillespie MN. Pharmacologic Protection of Mitochondrial DNA Integrity May Afford a New Strategy for Suppressing Lung Ischemia-Reperfusion Injury. Ann Am Thorac Soc. 2017 Sep;14(Supplement_3):S210-S215. PubMed PMID: 28945469
  • Kris MG, Gaspar LE, Chaft JE, Kennedy EB, Azzoli CG, Ellis PM, Lin SH, Pass HI, Seth R, Shepherd FA, Spigel DR, Strawn JR, Ung YC, Weyant M. Adjuvant Systemic Therapy and Adjuvant Radiation Therapy for Stage I to IIIA Completely Resected Non-Small-Cell Lung Cancers: American Society of Clinical Oncology/Cancer Care Ontario Clinical Practice Guideline Update. J Clin Oncol. 2017 Sep 1;35(25):2960-2974. PubMed PMID: 28437162
  • Stewart CL, Wilson L, Hamm A, Bartsch C, Boniface M, Gleisner A, Mitchell JD, Weyant MJ, Meguid R, Gajdos C, Edil BH, McCarter M. Is Chemical Pyloroplasty Necessary for Minimally Invasive Esophagectomy?. Ann Surg Oncol. 2017 May;24(5):1414-1418. PubMed PMID: 28058546
  • Jones TS, Sullivan A, Damle S, Weyant MJ, Mitchell JD, Weitzel NS, Meguid RA. Assessment and Management of Post-Intubation Airway Injuries. Semin Cardiothorac Vasc Anesth. 2017 Mar;21(1):99-104. PubMed PMID: 27166401
  • Bunn PA Jr, Gaspar LE, Weyant MJ, Mitchell JD. Neoadjuvant combination chemotherapy for unresectable stage III non-small cell lung cancer. Cancer. 2016 Mar 1;122(5):674-5. PubMed PMID: 26700372
  • Browning ET, Huckleberry JM, Barrow WB, Restauri NL, Kemme DJ, Cool CD, Weyant MJ, Franklin WA, Camidge DR. Downstaging of Non-Small-Cell Lung Cancer Through Identification of Reversible Drug Toxicity. J Clin Oncol. 2016 Jan 10;34(2):e6-8. PubMed PMID: 24799494
  • Weyant MJ. The year in thoracic surgery: highlights from 2014. Semin Cardiothorac Vasc Anesth. 2015 Mar;19(1):24-8. PubMed PMID: 25667305
  • Bennett DT, Reece TB, Foley LS, Sjoberg A, Meng X, Fullerton DA, Weyant MJ. C-terminal tensin-like protein mediates invasion of human lung cancer cells and is regulated by signal transducer and activator of transcription 3. J Thorac Cardiovasc Surg. 2015 Jan;149(1):369-75. PubMed PMID: 25439778
  • Freeman KA, Fullerton DA, Foley LS, Bell MT, Cleveland JC Jr, Weyant MJ, Mares J, Meng X, Puskas F, Reece TB. Spinal cord protection via alpha-2 agonist-mediated increase in glial cell-line-derived neurotrophic factor. J Thorac Cardiovasc Surg. 2015 Feb;149(2):578-84; discussion 584-6. PubMed PMID: 25454921
  • Mares JM, Foley LS, Bell MT, Bennett DT, Freeman KA, Meng X, Weyant MJ, Cleveland JC Jr, Fullerton DA, Puskas F, Reece TB. Erythropoietin activates the phosporylated cAMP [adenosine 3'5' cyclic monophosphate] response element-binding protein pathway and attenuates delayed paraplegia after ischemia-reperfusion injury. J Thorac Cardiovasc Surg. 2015 Mar;149(3):920-4. PubMed PMID: 25500291
  • Freeman KA, Puskas F, Bell MT, Mares JM, Foley LS, Weyant MJ, Cleveland JC Jr, Fullerton DA, Meng X, Herson PS, Reece TB. Alpha-2 agonist attenuates ischemic injury in spinal cord neurons. J Surg Res. 2015 May 1;195(1):21-8. PubMed PMID: 25655994
  • Weyant MJ. The year in thoracic surgery: highlights from 2014. Semin Cardiothorac Vasc Anesth. 2015 Mar;19(1):24-8. PubMed PMID: 25667305
  • Foley LS, Fullerton DA, Bennett DT, Freeman KA, Mares J, Bell MT, Cleveland JC Jr, Weyant MJ, Meng X, Puskas F, Reece TB. Spinal Cord Ischemia-Reperfusion Injury Induces Erythropoietin Receptor Expression. Ann Thorac Surg. 2015 Jul;100(1):41-6; discussion 46. PubMed PMID: 25865765
  • Venardos N, Bennett D, Weyant MJ, Reece TB, Meng X, Fullerton DA. Matrix Gla protein regulates calcification of the aortic valve. J Surg Res. 2015 Nov;199(1):1-6. PubMed PMID: 25990696
  • Bell MT, Puskas F, Bennett DT, Cleveland JC Jr, Herson PS, Mares JM, Meng X, Weyant MJ, Fullerton DA, Brett Reece T. Clinical indicators of paraplegia underplay universal spinal cord neuronal injury from transient aortic occlusion. Brain Res. 2015 Aug 27;1618:55-60. PubMed PMID: 26005132
  • Hazel K, Weyant MJ. Chest Wall Resection and Reconstruction: Management of Complications. Thorac Surg Clin. 2015 Nov;25(4):517-21. PubMed PMID: 26515951
  • Bunn PA Jr, Gaspar LE, Weyant MJ, Mitchell JD. Neoadjuvant combination chemotherapy for unresectable stage III non-small cell lung cancer. Cancer. 2015 Dec 23. [Epub ahead of print] PubMed PMID: 26700372
  • Bennett DT, Zamora M, Reece TB, Mitchell JD, Cleveland JC Jr, Grover FL, Babu AN, Meguid RA, Fullerton DA, Weyant MJ. Continued Utility of Single-Lung Transplantation in Select Populations: Chronic Obstructive Pulmonary Disease. Ann Thorac Surg. 2015 Aug;100(2):437-42. PubMed PMID: 26141775
  • Freeman KA, Puskas F, Bell MT, Mares JM, Foley LS, Weyant MJ, Cleveland JC Jr, Fullerton DA, Meng X, Herson PS, Reece TB. Alpha-2 agonist attenuates ischemic injury in spinal cord neurons. J Surg Res. 2014 Dec 23. [Epub ahead of print] PubMed PMID: 25655994
  • Mares JM, Foley LS, Bell MT, Bennett DT, Freeman KA, Meng X, Weyant MJ, Cleveland JC Jr, Fullerton DA, Puskas F, Reece TB. Erythropoietin activates the phosporylated cAMP [adenosine 3'5' cyclic monophosphate] response element-binding protein pathway and attenuates delayed paraplegia after ischemia-reperfusion injury. J Thorac Cardiovasc Surg. 2014 Nov 13. [Epub ahead of print] PubMed PMID: 25500291
  • Bennett DT, Weyant MJ. Extended chest wall resection and reconstruction in the setting of lung cancer. Thorac Surg Clin. 2014 Nov;24(4):383-90. PubMed PMID: 25441131
  • Bennett DT, Reece TB, Smith PD, Grandhi MS, Rove JA, Justison GA, Mitchell JD, Fullerton DA, Zamora MR, Weyant MJ. Ex vivo lung perfusion allows successful transplantation of donor lungs from hanging victims. Ann Thorac Surg. 2014 Sep;98(3):1051-6. PubMed PMID: 25038007
  • Bennett DT, Deng XS, Yu JA, Bell MT, Mauchley DC, Meng X, Reece TB, Fullerton DA, Weyant MJ. Cancer stem cell phenotype is supported by secretory phospholipase A2 in human lung cancer cells. Ann Thorac Surg. 2014 Aug;98(2):439-45; discussion 445-6. PubMed PMID: 24928671
  • Browning ET, Huckleberry JM, Barrow WB, Restauri NL, Kemme DJ, Cool CD, Weyant MJ, Franklin WA, Camidge DR. Downstaging of Non-Small-Cell Lung Cancer Through Identification of Reversible Drug Toxicity. J Clin Oncol. 2014 May 5. [Epub ahead of print] PubMed PMID: 24799494
  • Alegre MM, Weyant MJ, Bennett DT, Yu JA, Ramsden MK, Elnaggar A, Robison RA, O'Neill KL. Serum detection of thymidine kinase 1 as a means of early detection of lung cancer. Anticancer Res. 2014 May;34(5):2145-51. PubMed PMID: 24778016
  • Venardos N, Nadlonek NA, Zhan Q, Weyant MJ, Reece TB, Meng X, Fullerton DA. Aortic valve calcification is mediated by a differential response of aortic valve interstitial cells to inflammation. J Surg Res. 2014 Jul;190(1):1-8. PubMed PMID: 24746950
  • Bell MT, Reece TB, Smith PD, Mares J, Weyant MJ, Cleveland JC Jr, Freeman KA, Fullerton DA, Puskas F. Reproducable paraplegia by thoracic aortic occlusion in a murine model of spinal cord ischemia-reperfusion. J Vis Exp. 2014 Mar 3;(85). PubMed PMID: 24637534
  • Bennett DT, Weyant MJ. The year in thoracic surgery: highlights from 2013. Semin Cardiothorac Vasc Anesth. 2014 Mar;18(1):24-8. PubMed PMID: 24501225
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Professional Memberships

  • American Association for Cancer Research, Member
  • Society of Thoracic Surgeons, Member
  • American College of Surgeons Oncology Group, Member
  • American College of Chest Physicians, Fellow
  • Colorado Thoracic Society, Member
  • University of Colorado Cancer Center, Member
  • Southwest Oncology Group, Member
  • American College of Surgeons (ACS), Fellow
  • International Society for Heart and Lung Transplantation, Member
  • International Association for the Study of Lung Cancer, Member
  • Society for Surgery of the Alimentary Tract, Member
  • General Thoracic Surgical Club, Member
  • Western Thoracic Surgical Association, Member
  • European Society of Thoracic Surgeons, Member

Practice Locations

Transplant Services - Anschutz
1635 Aurora Ct
7th Floor
Aurora, CO 80045
720-848-0005

National Jewish Health
1400 Jackson St
Denver, CO 80206
1-877-225-5654

Saint Joseph Hospital
1375 E. 19th Avenue
Denver, CO 80218
303-812-2000

UCHealth Thoracic Surgery - Anschutz Medical Campus
1665 Aurora Court
Anschutz Cancer Pavilion, 2nd Floor
Aurora, CO 80045
303-724-2799

CU Specialty Care at Highlands Ranch - Thoracic Surgery
1500 Park Central Drive, Suite 101
Highlands Ranch, CO 80129
720-516-1093

UCHealth Surgical Care – Highlands Ranch Hospital
1500 Park Central Drive
Highlands Ranch, CO 80129
720-516-1000

Hospital Affiliation
  • University of Colorado Hospital
  • National Jewish Health
  • Saint Joseph Hospital
  • UCHealth Highlands Ranch Hospital
Center Affiliations

Specialty Information

Specialties
  • Surgery, Board Certification (2004)
  • Thoracic and Cardiac, Board Certification (2006)
Conditions & Treatments
  • Cancers - Cancer Surgery
  • Cancers - Lung Cancer
  • Surgery - Cardiothoracic Surgery
  • Surgery - Transplant Surgery
  • Surgery - Adult General Thoracic Surgery
  • Surgery - Lung Transplant Surgery
  • Surgery - Infectious Lung Disease
  • Cancers - Thoracic (Tracheal, Esophageal)
  • Cancers
  • Surgery
Clinical Interests
My expertise and interests are in benign and malignant esophageal surgery, minimally invasive thoracic procedures, neoplasms of the lung and mediastinum, endoluminal therapies, chest wall resection and reconstruction, and surgery for end stage lung disease.

General Information

Medical Schools:
  • MD, Mount Sinai School of Medicine (1996)
Undergraduate Schools:
  • BS, Syracuse University (NY) (1992)
Internships:
  • New York Presbyterian Hospital (Cornell Campus) Program (1997)
Residency Programs:
  • New York Presbyterian Hospital (Cornell Campus) Program, Surgery (2003)
Fellowships:
  • Memorial Sloan-Kettering Cancer Center/New York Presbyterian Hospital (Cornell Campus) Program, Thoracic and Cardiac (2005)
Languages: English
Department: Surgery-Cardiothoracic
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