Nicholas Cost, MD
Associate Professor, Surgery-Urology

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Medical School:
  • MD, Emory University School of Medicine (2005)
Undergraduate School:
  • BS, Vanderbilt University (TN) (2001)
Internship:
  • University of Texas Southwestern Medical School Program (2006)
Residency:
  • University of Texas Southwestern Medical School Program, Chief Resident, Urology (2010)
Fellowships:
  • University of Texas Southwestern Medical School Program, Urologic Oncology (2011)
  • Cincinnati Children's Hospital Medical Center/University of Cincinnati College of Medicine Program, Pediatric Urology (2013)
Languages: English, Italian
Department: Surgery-Urology

Professional Titles

  • Associate Professor, Surgery-Urology
  • Assistant Professor

Research Interests

My Research Interests include: (1) Clinical trials for children, adolescents, and young adults with urologic tumors and cancers, specifically surgical and long-term outcomes in this population. (2) Understanding the background science, genetics, and developing new therapies in Wilms tumor, Renal Cell Carcinoma and Testicular Tumors.

Teaching

  • Assistant Professor (2013)
    School of Medicine, Surgery
    Clinical Interests: Urologic malignancies in children, adolescents, and young adults (Kidney Tumors: Wilms Tumor, RCC, Angiomyolipomas; Testicular Tumors; Pelvic, Bladder, and Prostate Tumors: Rhabdomyosarcoma); Tumor predisposition syndromes such as von Hippel Lindau, Tuberous Sclerosis, and Birt-Hogg-Dube; Minimally invasive surgery (robotic-assisted laparoscopy, laparoscopy, and endoscopy) for all variety of urologic conditions; Ureteropelvic junction obstruction Vesicoureteral reflux, and Urolithiasis (kidney stones). Research Interests: Clinical trials for children, adolescents, and young adults with urologic malignancies, specifically surgical and long-term outcomes in this population. Molecular pathways, genetics, and developing novel therapies in Wilms tumor, Renal Cell Carcinoma and Testicular Tumors.

Publications

  • Saltzman AF, Carrasco A Jr, Amini A, Cost NG. Patterns of Care and Survival Comparison of Adult and Pediatric Wilms Tumor in the United States: A Study of the National Cancer Database. Urology. 2019 Oct 25. [Epub ahead of print] PubMed PMID: 31669270
  • Loomis J, Peard L, Walker J, Cost NG, Saltzman AF. Open Radical Nephrectomy for Suspected Renal Malignancy-Tips and Tricks. Urology. 2019 Nov;133:241-242. PubMed PMID: 31419431
  • Romero NG, Walker J, Cost NG, Saltzman AF. Partial Nephrectomy for Multifocal, Unilateral Wilms Tumor in a Patient with Hemihypertrophy. Urology. 2019 Nov;133:243-244. PubMed PMID: 31404584
  • Saltzman AF, Smith DE, Gao D, Ghosh D, Amini A, Aldrink JH, Dasgupta R, Gow KW, Glick RD, Ehrlich PF, Cost NG. How Many Lymph Nodes Are Enough? Assessing the Adequacy of Lymph Node Yield for Staging in Favorable Histology Wilms Tumor. J Pediatr Surg. 2019 Jun 20. [Epub ahead of print] PubMed PMID: 31255328
  • Peard L, Cost NG, Saltzman AF. Pediatric pheochromocytoma: current status of diagnostic imaging and treatment procedures. Curr Opin Urol. 2019 Sep;29(5):493-499. PubMed PMID: 31246590
  • Cost NG. Expert opinion: open primary, nerve-sparing retroperitoneal lymph node dissection. J Pediatr Urol. 2019 May;15(3):273. PubMed PMID: 31221397
  • Saltzman AF, Carrasco A Jr, Hecht S, Walker J, Caldwell BT, Bruny JL, Cost NG. A decision tree to guide long term venous access placement in children and adolescents undergoing surgery for renal tumors. J Pediatr Surg. 2019 May 11. [Epub ahead of print] PubMed PMID: 31128844
  • Iguchi N, Dönmez MI, Carrasco A Jr, Wilcox DT, Pineda RH, Malykhina AP, Cost NG. Doxorubicin induces detrusor smooth muscle impairments through myosin dysregulation, leading to a risk of lower urinary tract dysfunction. Am J Physiol Renal Physiol. 2019 Jul 1;317(1):F197-F206. PubMed PMID: 31066574
  • Saltzman AF, Stokes W, Walker J, Cost NG. Factors related to lymph node sampling at the time of surgery in children, adolescents, and young adults with unilateral non-metastatic renal cell carcinoma. J Pediatr Urol. 2019 May;15(3):259.e1-259.e7. PubMed PMID: 30819622
  • Walker JP, Meyers ML, Saltzman AF, Hecht SL, Cost NG. The Natural History of Wilms Tumor-A Case Comparison of Two Different Tumors. Urology. 2019 Aug;130:151-154. PubMed PMID: 30807774
  • Goodstein TA, Cost NG, Campbell JB, Vemulakonda V, Wilcox D, Saltzman AF. A Contemporary Analysis of Pediatric Urology Surgical Volume at a Tertiary Care Center. Urology. 2019 Mar;125:179-183. PubMed PMID: 30610906
  • Walker JP, Saltzman AF, Kessler ER, Cost NG. Adult Wilms Tumor During Pregnancy: Case Report and Literature Review. Urology. 2019 Jul;129:200-205. PubMed PMID: 30597169
  • Caldwell BT, Saltzman AF, Maccini MA, Cost NG. Appropriateness for testis-sparing surgery based on the testicular tumor size in a pediatric and adolescent population. J Pediatr Urol. 2018 Oct 23. [Epub ahead of print] PubMed PMID: 30448079
  • Peard L, Cost NG, Saltzman AF. Dermatofibrosarcoma Protuberans in a Male Infant. Urology. 2018 Nov 10. [Epub ahead of print] PubMed PMID: 30423303
  • Luckie TM, Danzig M, Zhou S, Wu H, Cost NG, Karaviti L, Venkatramani R. A Multicenter Retrospective Review of Pediatric Leydig Cell Tumor of the Testis. J Pediatr Hematol Oncol. 2018 Mar 16. [Epub ahead of print] PubMed PMID: 29554024
  • Aldrink JH, Cost NG, McLeod DJ, Bates DG, Stanek JR, Smith EA, Ehrlich PF. Technical Considerations for Nephron-Sparing Surgery in Children: What Is Needed to Preserve Renal Units?. J Surg Res. 2018 Dec;232:614-620. PubMed PMID: 30463781
  • Caldwell BT, Saltzman AF, Maccini MA, Cost NG. Appropriateness for testis-sparing surgery based on the testicular tumor size in a pediatric and adolescent population. J Pediatr Urol. 2018 Oct 23. [Epub ahead of print] PubMed PMID: 30448079
  • Peard L, Cost NG, Saltzman AF. Dermatofibrosarcoma Protuberans in a Male Infant. Urology. 2018 Nov 10. [Epub ahead of print] PubMed PMID: 30423303
  • Johnson JS, Saltzman AF, Treece AL, Cost NG. A case of IgG4-related renal pseudotumor in a child with history of Wilms tumor. Urol Case Rep. 2018 Nov;21:107-109. PubMed PMID: 30276130
  • Islam M, Saltzman AF, Amini A, Carrasco A Jr, Cost NG. Factors Influencing Overall Survival of Children, Adolescents, and Young Adults With High-risk Renal Tumors. Urology. 2018 Oct;120:222-230. PubMed PMID: 30076944
  • Cajaiba MM, Dyer LM, Geller JI, Jennings LJ, George D, Kirschmann D, Rohan SM, Cost NG, Khanna G, Mullen EA, Dome JS, Fernandez CV, Perlman EJ. The classification of pediatric and young adult renal cell carcinomas registered on the children's oncology group (COG) protocol AREN03B2 after focused genetic testing. Cancer. 2018 Aug;124(16):3381-3389. PubMed PMID: 29905933
  • Saltzman AF, Warncke JC, Colvin AN, Carrasco A Jr, Roach JP, Bruny JL, Cost NG. Development of a postoperative care pathway for children with renal tumors. J Pediatr Urol. 2018 Aug;14(4):326.e1-326.e6. PubMed PMID: 29891188
  • Saltzman AF, Cost NG. Adolescent and Young Adult Testicular Germ Cell Tumors: Special Considerations. Adv Urol. 2018;2018:2375176. PubMed PMID: 29662516
  • Saltzman AF, Carrasco A Jr, Colvin AN, Meyers ML, Cost NG. Can a Modified Bosniak Classification System Risk Stratify Pediatric Cystic Renal Masses?. J Urol. 2018 Aug;200(2):434-439. PubMed PMID: 29572157
  • Stokes CL, Stokes WA, Kalapurakal JA, Paulino AC, Cost NG, Cost CR, Garrington TP, Greffe BS, Roach JP, Bruny JL, Liu AK. Timing of Radiation Therapy in Pediatric Wilms Tumor: A Report From the National Cancer Database. Int J Radiat Oncol Biol Phys. 2018 Jun 1;101(2):453-461. PubMed PMID: 29559286
  • Luckie TM, Danzig M, Zhou S, Wu H, Cost NG, Karaviti L, Venkatramani R. A Multicenter Retrospective Review of Pediatric Leydig Cell Tumor of the Testis. J Pediatr Hematol Oncol. 2018 Mar 16. [Epub ahead of print] PubMed PMID: 29554024
  • Colvin A, Saltzman AF, Walker J, Bruny J, Cost NG. Metastatic Pheochromocytoma in an Asymptomatic 12-Year-Old With von Hippel-Lindau Disease. Urology. 2018 Sep;119:140-142. PubMed PMID: 29545044
  • Saltzman AF, Cost NG. Current Treatment of Pediatric Bladder and Prostate Rhabdomyosarcoma. Curr Urol Rep. 2018 Feb 22;19(1):11. PubMed PMID: 29468476
  • Brodie KE, Saltzman AF, Cost NG. Adolescent testicular microlithiasis: A case-based, multinational survey of clinical management practices. J Pediatr Urol. 2018 Apr;14(2):151.e1-151.e8. PubMed PMID: 29428360
  • Cost NG, Aldrink JH, Saltzman AF, Dasgupta R, Gow KW, Glick R, Ehrlich PF. Current state of renal tumor surgery among pediatric surgeons and pediatric urologists: A survey of American Pediatric Surgical Association (APSA) and Society for Pediatric Urology (SPU) members. J Pediatr Urol. 2018 Apr;14(2):168.e1-168.e8. PubMed PMID: 29246796
  • Saltzman AF, Carrasco A Jr, Weinman J, Meyers ML, Cost NG. INITIAL IMAGING FOR PEDIATRIC RENAL TUMORS - AN OPPORTUNITY FOR IMPROVEMENT. J Urol. 2017 Nov 24. [Epub ahead of print] PubMed PMID: 29180299
  • Saltzman AF, Carrasco A Jr, Amini A, Aldrink JH, Dasgupta R, Gow KW, Glick RD, Ehrlich PF, Cost NG. Patterns of lymph node sampling and the impact of lymph node density in favorable histology Wilms tumor: An analysis of the national cancer database. J Pediatr Urol. 2017 Oct 31. [Epub ahead of print] PubMed PMID: 29133167
  • Aldrink JH, Cost NG, McLeod DJ, Bates DG, Stanek JR, Smith EA, Ehrlich PF. Technical Considerations for Nephron-Sparing Surgery in Children: What Is Needed to Preserve Renal Units?. J Surg Res. 2018 Dec;232:614-620. PubMed PMID: 30463781
  • Aldrink JH, Cost NG, McLeod DJ, Bates DG, Stanek JR, Smith EA, Ehrlich PF. Technical Considerations for Nephron-Sparing Surgery in Children: What Is Needed to Preserve Renal Units?. J Surg Res. 2018 Dec;232:614-620. PubMed PMID: 30463781
  • Aldrink JH, Cost NG, McLeod DJ, Bates DG, Stanek JR, Smith EA, Ehrlich PF. Technical Considerations for Nephron-Sparing Surgery in Children: What Is Needed to Preserve Renal Units?. J Surg Res. 2018 Dec;232:614-620. PubMed PMID: 30463781
  • Johnson JS, Saltzman AF, Treece AL, Cost NG. A case of IgG4-related renal pseudotumor in a child with history of Wilms tumor. Urol Case Rep. 2018 Nov;21:107-109. PubMed PMID: 30276130
  • Islam M, Saltzman AF, Amini A, Carrasco A Jr, Cost NG. Factors Influencing Overall Survival of Children, Adolescents, and Young Adults With High-risk Renal Tumors. Urology. 2018 Oct;120:222-230. PubMed PMID: 30076944
  • Johnson JS, Saltzman AF, Treece AL, Cost NG. A case of IgG4-related renal pseudotumor in a child with history of Wilms tumor. Urol Case Rep. 2018 Nov;21:107-109. PubMed PMID: 30276130
  • Cajaiba MM, Dyer LM, Geller JI, Jennings LJ, George D, Kirschmann D, Rohan SM, Cost NG, Khanna G, Mullen EA, Dome JS, Fernandez CV, Perlman EJ. The classification of pediatric and young adult renal cell carcinomas registered on the children's oncology group (COG) protocol AREN03B2 after focused genetic testing. Cancer. 2018 Aug;124(16):3381-3389. PubMed PMID: 29905933
  • Saltzman AF, Warncke JC, Colvin AN, Carrasco A Jr, Roach JP, Bruny JL, Cost NG. Development of a postoperative care pathway for children with renal tumors. J Pediatr Urol. 2018 Aug;14(4):326.e1-326.e6. PubMed PMID: 29891188
  • Saltzman AF, Cost NG. Adolescent and Young Adult Testicular Germ Cell Tumors: Special Considerations. Adv Urol. 2018;2018:2375176. PubMed PMID: 29662516
  • Saltzman AF, Carrasco A Jr, Colvin AN, Meyers ML, Cost NG. Can a Modified Bosniak Classification System Risk Stratify Pediatric Cystic Renal Masses?. J Urol. 2018 Aug;200(2):434-439. PubMed PMID: 29572157
  • Stokes CL, Stokes WA, Kalapurakal JA, Paulino AC, Cost NG, Cost CR, Garrington TP, Greffe BS, Roach JP, Bruny JL, Liu AK. Timing of Radiation Therapy in Pediatric Wilms Tumor: A Report From the National Cancer Database. Int J Radiat Oncol Biol Phys. 2018 Jun 1;101(2):453-461. PubMed PMID: 29559286
  • Colvin A, Saltzman AF, Walker J, Bruny J, Cost NG. Metastatic Pheochromocytoma in an Asymptomatic 12-Year-Old With von Hippel-Lindau Disease. Urology. 2018 Sep;119:140-142. PubMed PMID: 29545044
  • Saltzman AF, Cost NG. Current Treatment of Pediatric Bladder and Prostate Rhabdomyosarcoma. Curr Urol Rep. 2018 Feb 22;19(1):11. PubMed PMID: 29468476
  • Brodie KE, Saltzman AF, Cost NG. Adolescent testicular microlithiasis: A case-based, multinational survey of clinical management practices. J Pediatr Urol. 2018 Apr;14(2):151.e1-151.e8. PubMed PMID: 29428360
  • Cost NG, Aldrink JH, Saltzman AF, Dasgupta R, Gow KW, Glick R, Ehrlich PF. Current state of renal tumor surgery among pediatric surgeons and pediatric urologists: A survey of American Pediatric Surgical Association (APSA) and Society for Pediatric Urology (SPU) members. J Pediatr Urol. 2018 Apr;14(2):168.e1-168.e8. PubMed PMID: 29246796
  • Saltzman AF, Carrasco A Jr, Weinman J, Meyers ML, Cost NG. INITIAL IMAGING FOR PEDIATRIC RENAL TUMORS - AN OPPORTUNITY FOR IMPROVEMENT. J Urol. 2017 Nov 24. [Epub ahead of print] PubMed PMID: 29180299
  • Saltzman AF, Carrasco A Jr, Amini A, Aldrink JH, Dasgupta R, Gow KW, Glick RD, Ehrlich PF, Cost NG. Patterns of lymph node sampling and the impact of lymph node density in favorable histology Wilms tumor: An analysis of the national cancer database. J Pediatr Urol. 2017 Oct 31. [Epub ahead of print] PubMed PMID: 29133167
  • Saltzman AF, Carrasco A Jr, Weinman J, Meyers ML, Cost NG. INITIAL IMAGING FOR PEDIATRIC RENAL TUMORS - AN OPPORTUNITY FOR IMPROVEMENT. J Urol. 2017 Nov 24. [Epub ahead of print] PubMed PMID: 29180299
  • Saltzman AF, Carrasco A Jr, Amini A, Aldrink JH, Dasgupta R, Gow KW, Glick RD, Ehrlich PF, Cost NG. Patterns of lymph node sampling and the impact of lymph node density in favorable histology Wilms tumor: An analysis of the national cancer database. J Pediatr Urol. 2017 Oct 31. [Epub ahead of print] PubMed PMID: 29133167
  • Schultz KAP, Harris AK, Finch M, Dehner LP, Brown JB, Gershenson DM, Young RH, Field A, Yu W, Turner J, Cost NG, Schneider DT, Stewart DR, Frazier AL, Messinger Y, Hill DA. DICER1-related Sertoli-Leydig cell tumor and gynandroblastoma: Clinical and genetic findings from the International Ovarian and Testicular Stromal Tumor Registry. Gynecol Oncol. 2017 Dec;147(3):521-527. PubMed PMID: 29037807
  • Sandberg JK, Mullen EA, Cajaiba MM, Smith EA, Servaes S, Perlman EJ, Geller JI, Ehrlich PF, Cost NG, Dome JS, Fernandez CV, Khanna G. Imaging of renal medullary carcinoma in children and young adults: a report from the Children's Oncology Group. Pediatr Radiol. 2017 Nov;47(12):1615-1621. PubMed PMID: 28689245
  • Caldwell BT, Wilcox DT, Cost NG. Current Management for Pediatric Urologic Oncology. Adv Pediatr. 2017 Aug;64(1):191-223. PubMed PMID: 28688589
  • Stokes W, Amini A, Maroni PD, Kessler ER, Stokes C, Cost CR, Greffe BS, Garrington TP, Liu AK, Cost NG. Patterns of care and survival outcomes for adolescent and young adult patients with testicular seminoma in the United States: A National Cancer Database analysis. J Pediatr Urol. 2017 Jan 17. [Epub ahead of print] PubMed PMID: 28153774
  • Carrasco A Jr, Caldwell BT, Cost CR, Greffe BS, Garrington TP, Bruny JL, Black JO, Cost NG. Reliability of intraoperative frozen section for the diagnosis of renal tumors suspicious for malignancy in children and adolescents. Pediatr Blood Cancer. 2017 Jan 18. [Epub ahead of print] PubMed PMID: 28097784
  • Saltzman AF, Carrasco A Jr, Maccini MA, Caldwell BT, Treece AL, Cost NG. Large Cystic Metanephric Adenoma in a 15 Year Old Girl. Urology. 2016 Dec 20. [Epub ahead of print] PubMed PMID: 28011277
  • Cost NG, Ross JH, Ferrer FA, Lorenzo AJ, Shnorhavorian M, Routh JC, Kieran K, Ritchey ML. Patterns of Performance of Oncologic Surgery by North American Pediatric Urologists: A Report from the Pediatric Urologic Oncology Working Group of the Society for Pediatric Urology. J Urol. 2017 May;197(5):1349-1354. PubMed PMID: 27986529
  • Cost NG. Editorial Comment: "Zero-Ischemia" Laparoscopic-assisted Partial Nephrectomy for the Management of Selected Children With Wilms Tumor Following Neoadjuvant Chemotherapy. Urology. 2016 Nov 14. [Epub ahead of print] PubMed PMID: 27855980
  • Cost NG, Ferrer FA, Lorenzo AJ, Shnorhavorian M, Kieran K, Routh JC, Ritchey ML, Ross JH. A Society for Pediatric Urology Workforce Survey on the Current Perceptions of Oncology Care by Pediatric Urologists: A Report from the Pediatric Urologic Oncology Working Group of the Society for Pediatric Urology. J Urol. 2016 Nov 9. [Epub ahead of print] PubMed PMID: 27837647
  • Syed JS, Nguyen KA, Wu CQ, Cost NG, Siddiqui MM, Hittelman AB, Shuch B. Distinguishing pediatric and adolescent renal cell carcinoma from other renal malignancies. Pediatr Blood Cancer. 2016 Nov 2. [Epub ahead of print] PubMed PMID: 27805307
  • Arevalo MK, Prieto JC, Cost N, Nuss G, Brown BJ, Baker LA. Utility of retrograde ureterocelogram in management of complex ureterocele. J Pediatr Urol. 2016 Sep 17. [Epub ahead of print] PubMed PMID: 27697471
  • Warncke JC, Brodie KE, Grantham EC, Catarinicchia SP, Tong S, Kondo KL, Cost NG. Pediatric Renal Angiomyolipomas in Tuberous Sclerosis Complex. J Urol. 2016 Sep 25. [Epub ahead of print] PubMed PMID: 27678300
  • Cost NG. Editorial Comment. J Urol. 2016 Sep 21. [Epub ahead of print] PubMed PMID: 27664514
  • Cost NG, Stock JA. A brief history of pediatric urologic oncology as a subspecialty. Urol Oncol. 2016 Jan;34(1):7-8. PubMed PMID: 26420020
  • Cost NG. Editorial Comment: "Zero-Ischemia" Laparoscopic-assisted Partial Nephrectomy for the Management of Selected Children With Wilms Tumor Following Neoadjuvant Chemotherapy. Urology. 2016 Nov 14. [Epub ahead of print] PubMed PMID: 27855980
  • Cost NG, Ferrer FA, Lorenzo AJ, Shnorhavorian M, Kieran K, Routh JC, Ritchey ML, Ross JH. A Society for Pediatric Urology Workforce Survey on the Current Perceptions of Oncology Care by Pediatric Urologists: A Report from the Pediatric Urologic Oncology Working Group of the Society for Pediatric Urology. J Urol. 2016 Nov 9. [Epub ahead of print] PubMed PMID: 27837647
  • Syed JS, Nguyen KA, Wu CQ, Cost NG, Siddiqui MM, Hittelman AB, Shuch B. Distinguishing pediatric and adolescent renal cell carcinoma from other renal malignancies. Pediatr Blood Cancer. 2016 Nov 2. [Epub ahead of print] PubMed PMID: 27805307
  • Arevalo MK, Prieto JC, Cost N, Nuss G, Brown BJ, Baker LA. Utility of retrograde ureterocelogram in management of complex ureterocele. J Pediatr Urol. 2016 Sep 17. [Epub ahead of print] PubMed PMID: 27697471
  • Warncke JC, Brodie KE, Grantham EC, Catarinicchia SP, Tong S, Kondo KL, Cost NG. Pediatric Renal Angiomyolipomas in Tuberous Sclerosis Complex. J Urol. 2016 Sep 25. [Epub ahead of print] PubMed PMID: 27678300
  • Cost NG. Editorial Comment. J Urol. 2016 Sep 21. [Epub ahead of print] PubMed PMID: 27664514
  • Amini A, Waxweiler TV, Maroni PD, Kessler ER, Cost CR, Greffe BS, Garrington TP, Liu AK, Cost NG. Survival outcomes of adolescent and adult patients with non-seminomatous testicular germ-cell tumors: A population-based study. J Pediatr Urol. 2016 Aug 6. [Epub ahead of print] PubMed PMID: 27544905
  • Rove KO, Maroni PD, Cost CR, Fairclough DL, Giannarini G, Harris AK, Schultz KA, Cost NG. Pathologic Risk Factors for Metastatic Disease in Postpubertal Patients With Clinical Stage I Testicular Stromal Tumors. Urology. 2016 Aug 15. [Epub ahead of print] PubMed PMID: 27538802
  • Cost NG, Stock JA. Current and Future Issues in Pediatric and Adolescent Urologic Oncology. Urology. 2016 May;91:174. PubMed PMID: 27107195
  • Cost NG, Caldwell BT, Adibi M, Raj GV, Sagalowsky AI, Margulis V. Do Referral Patterns in Adolescents and Young Adults with Testicular Cancer Impact Oncologic Outcomes?. J Adolesc Young Adult Oncol. 2016 Sep;5(3):248-53. PubMed PMID: 26871870
  • Cost NG, Stock JA. The future of pediatric and adolescent urologic oncology as a subspecialty: Gains and growth via research, education, and quality improvement. Urol Oncol. 2015 Oct 21. [Epub ahead of print] PubMed PMID: 26507389
  • Cost NG, Stock JA. A brief history of pediatric urologic oncology as a subspecialty. Urol Oncol. 2016 Jan;34(1):7-8. PubMed PMID: 26420020
  • Grantham EC, Caldwell BT, Cost NG. Current urologic care for testicular germ cell tumors in pediatric and adolescent patients. Urol Oncol. 2015 Jul 14. [Epub ahead of print] PubMed PMID: 26187598
  • Cost NG, Liss ZJ, Bean CM, Geller JI, Minevich EA, Noh PH. Prechemotherapy Robotic-assisted Laparoscopic Radical Nephrectomy for an Adolescent With Wilms Tumor. J Pediatr Hematol Oncol. 2015 Mar;37(2):e125-7. PubMed PMID: 24878620
  • Caldwell BT, Cost CR, Cost NG. Large Bladder Mass and Renal Failure in a 14-Year-Old Boy. Oncology (Williston Park). 2015 Dec;29(12). PubMed PMID: 26676896
  • Cost NG, Stock JA. The future of pediatric and adolescent urologic oncology as a subspecialty: Gains and growth via research, education, and quality improvement. Urol Oncol. 2015 Oct 21. [Epub ahead of print] PubMed PMID: 26507389
  • Ha SC, Zlomke HA, Cost N, Wilson S. The Past, Present, and Future in Management of Small Renal Masses. J Oncol. 2015;2015:364807. PubMed PMID: 26491445
  • Rove KO, Maroni PD, Cost CR, Fairclough DL, Giannarini G, Harris AK, Schultz KA, Cost NG. Pathologic Risk Factors in Pediatric and Adolescent Patients With Clinical Stage I Testicular Stromal Tumors. J Pediatr Hematol Oncol. 2015 Nov;37(8):e441-6. PubMed PMID: 26479987
  • Grantham EC, Caldwell BT, Cost NG. Current urologic care for testicular germ cell tumors in pediatric and adolescent patients. Urol Oncol. 2015 Jul 14. [Epub ahead of print] PubMed PMID: 26187598
  • Waxweiler TV, Rusthoven CG, Proper MS, Cost CR, Cost NG, Donaldson N, Garrington T, Greffe BS, Heare T, Macy ME, Liu AK. Non-Rhabdomyosarcoma Soft Tissue Sarcomas in Children: A Surveillance, Epidemiology, and End Results Analysis Validating COG Risk Stratifications. Int J Radiat Oncol Biol Phys. 2015 Jun 1;92(2):339-48. PubMed PMID: 25968827
  • Geller JI, Ehrlich PF, Cost NG, Khanna G, Mullen EA, Gratias EJ, Naranjo A, Dome JS, Perlman EJ. Characterization of adolescent and pediatric renal cell carcinoma: A report from the Children's Oncology Group study AREN03B2. Cancer. 2015 Jul 15;121(14):2457-64. PubMed PMID: 25845370
  • Cost NG. Commentary to "Robot-assisted laparoscopic pyeloplasty: Multi-institutional experience in infants". J Pediatr Urol. 2015 Jun;11(3):140. PubMed PMID: 25783202
  • Cost NG, Liss ZJ, Bean CM, Geller JI, Minevich EA, Noh PH. Prechemotherapy Robotic-assisted Laparoscopic Radical Nephrectomy for an Adolescent With Wilms Tumor. J Pediatr Hematol Oncol. 2015 Mar;37(2):e125-7. PubMed PMID: 24878620
  • Cost NG, Cost CR, Geller JI, Defoor WR Jr. Adolescent urologic oncology: Current issues and future directions. Urol Oncol. 2014 Feb;32(2):59-69. PubMed PMID: 23141778
  • Hall DP, Cost NG, Hegde S, Kellner E, Mikhaylova O, Stratton Y, Ehmer B, Abplanalp WA, Pandey R, Biesiada J, Harteneck C, Plas DR, Meller J, Czyzyk-Krzeska MF. TRPM3 and miR-204 establish a regulatory circuit that controls oncogenic autophagy in clear cell renal cell carcinoma. Cancer Cell. 2014 Nov 10;26(5):738-53. PubMed PMID: 25517751
  • Bansal D, Cost NG, Bean CM, Minevich EA, Noh PH. Pediatric urological laparoendoscopic single site surgery: single surgeon experience. J Pediatr Urol. 2014 Dec;10(6):1170-5. PubMed PMID: 24993421
  • Chalmers DJ, O'Donnell CI, Casperson KJ, Berngard SC, Hou AH, Nuss GR, Cost NG, Wilcox DT. Normal anatomic relationships in prepubescent female external genitalia. J Pediatr Urol. 2014 Dec;10(6):1117-21. PubMed PMID: 24953545
  • Cost NG, Maroni P, Flaig TW. Metastatic relapse after initial clinical stage I testicular Leydig cell tumor. Oncology (Williston Park). 2014 Mar;28(3):211, 214. PubMed PMID: 24855728
  • Cost NG, Sawicz-Birkowska K, Kajbafzadeh AM, Tourchi A, Parigi GB, Guillén G, DeFoor WR Jr, Apoznanski W. A comparison of renal function outcomes after nephron-sparing surgery and radical nephrectomy for nonsyndromic unilateral Wilms tumor. Urology. 2014 Jun;83(6):1388-93. PubMed PMID: 24768019
  • Wang HH, Abern MR, Cost NG, Chu DI, Ross SS, Wiener JS, Routh JC. Use of nephron sparing surgery and impact on survival in children with Wilms tumor: a SEER analysis. J Urol. 2014 Oct;192(4):1196-202. PubMed PMID: 24735935
  • Cost NG, Lubahn JD, Adibi M, Romman A, Wickiser JE, Raj GV, Sagalowsky AI, Margulis V. Risk stratification of pubertal children and postpubertal adolescents with clinical stage I testicular nonseminomatous germ cell tumors. J Urol. 2014 May;191(5 Suppl):1485-90. PubMed PMID: 24679874
  • Bansal D, Cost NG, Bean CM, Vanderbrink BA, Schulte M, Noh PH. Infant robot-assisted laparoscopic upper urinary tract reconstructive surgery. J Pediatr Urol. 2014 Oct;10(5):869-74. PubMed PMID: 24661900
  • Cost NG, DeFoor WR Jr, Crotty EJ, Geller JI. The initial experience with RENAL Nephrometry in children, adolescents, and young adults with renal tumors. Pediatr Blood Cancer. 2014 Aug;61(8):1434-9. PubMed PMID: 24610879
  • Bansal D, Cost NG, Bean CM, Noh PH. Pediatric laparo-endoscopic single site partial nephrectomy: feasibility in infants and small children for upper urinary tract duplication anomalies. J Pediatr Urol. 2014 Oct;10(5):859-63. PubMed PMID: 24598458
  • Tasian GE, Cost NG, Granberg CF, Pulido JE, Rivera M, Schwen Z, Schulte M, Fox JA. Tamsulosin and spontaneous passage of ureteral stones in children: a multi-institutional cohort study. J Urol. 2014 Aug;192(2):506-11. PubMed PMID: 24518765
  • Bansal D, Cost NG, Defoor WR Jr, Reddy PP, Minevich EA, Vanderbrink BA, Alam S, Sheldon CA, Noh PH. Infant robotic pyeloplasty: Comparison with an open cohort. J Pediatr Urol. 2013 Nov 9. [Epub ahead of print] PubMed PMID: 24268880
  • Bansal D, Cost NG, Bean CM, Riachy E, Defoor WR Jr, Reddy PP, Minevich EA, Noh PH. Comparison of Pediatric Robotic-assisted Laparoscopic Nephroureterectomy and Laparoendoscopic Single-site Nephroureterectomy. Urology. 2013 Nov 6. [Epub ahead of print] PubMed PMID: 24210571
  • Cost NG, Lubahn JD, Adibi M, Romman A, Wickiser JE, Raj GV, Sagalowsky AI, Margulis V. A comparison of pediatric, adolescent, and adult testicular germ cell malignancy. Pediatr Blood Cancer. 2014 Mar;61(3):446-51. PubMed PMID: 24106160
  • Cost NG, Cost CR, Geller JI, Defoor WR Jr. Adolescent urologic oncology: Current issues and future directions. Urol Oncol. 2014 Feb;32(2):59-69. PubMed PMID: 23141778
  • Cost NG, Lubahn JD, Adibi M, Romman A, Wickiser JE, Raj GV, Sagalowsky AI, Margulis V. A comparison of pediatric, adolescent, and adult testicular germ cell malignancy. Pediatr Blood Cancer. 2014 Mar;61(3):446-51. PubMed PMID: 24106160
  • Youssef RF, Shariat SF, Lotan Y, Cost N, Wood CG, Sagalowsky AI, Zigeuner R, Langner C, Chromecki TF, Montorsi F, Bolenz C, Margulis V. Urothelial carcinoma at the uretero-enteric junction: multi-center evaluation of oncologic outcomes after radical nephroureterectomy. Urol Oncol. 2013 Jul;31(5):676-81. PubMed PMID: 21704538
  • Riachy E, Cost NG, Defoor WR, Reddy PP, Minevich EA, Noh PH. Pediatric standard and robot-assisted laparoscopic pyeloplasty: a comparative single institution study. J Urol. 2013 Jan;189(1):283-7. PubMed PMID: 23174238
  • Cost NG. Editorial comment. Urology. 2013 Jul;82(1):223; discussion 223-4. PubMed PMID: 23352366
  • Cost NG, Granberg CF, Schlomer BJ, Wickiser JE, Gargollo PC, Baker LA, Rakheja D. Single institution experience with Tru-Cut renal mass biopsy for diagnosing Wilms tumor. Urol J. 2013 Winter;10(1):780-3. PubMed PMID: 23504682
  • Applegate KE, Cost NG. Image Gently: a campaign to reduce children's and adolescents' risk for cancer during adulthood. J Adolesc Health. 2013 May;52(5 Suppl):S93-7. PubMed PMID: 23601618
  • Cost NG. Editorial comment. J Urol. 2013 Jul;190(1):233. PubMed PMID: 23619199
  • Walther A, Cost NG, Garrison AP, Geller JI, Alam S, Tiao GM. Renal rhabdomyosarcoma in a pancake kidney. Urology. 2013 Aug;82(2):458-60. PubMed PMID: 23639240
  • Cost NG. Testicular germ cell tumors. Current concepts and management strategies. Minerva Urol Nefrol. 2013 Jun;65(2):133-55. PubMed PMID: 23703101
  • Cost NG, Geller JI, Le LD, Crombleholme TM, Keswani SG, Lim FY, Alam S. Urologic co-morbidities associated with sacrococcygeal teratoma and a rational plan for urologic surveillance. Pediatr Blood Cancer. 2013 Oct;60(10):1626-9. PubMed PMID: 23776168
  • Cost NG, Noh PH, Devarajan P, Ivancic V, Reddy PP, Minevich E, Bennett M, Haffner C, Schulte M, DeFoor WR Jr. Urinary NGAL levels correlate with differential renal function in patients with ureteropelvic junction obstruction undergoing pyeloplasty. J Urol. 2013 Oct;190(4 Suppl):1462-7. PubMed PMID: 23791906
  • Cost NG, Krabbe LM, Bagrodia A, Margulis V. The use of preoperative targeted molecular therapy to allow nephron sparing for T1b tumors. Curr Opin Urol. 2013 Sep;23(5):411-7. PubMed PMID: 23841980
  • Bansal D, Cost NG, Bean CM, Riachy E, Defoor WR Jr, Reddy PP, Minevich EA, Noh PH. Comparison of Pediatric Robotic-assisted Laparoscopic Nephroureterectomy and Laparoendoscopic Single-site Nephroureterectomy. Urology. 2013 Nov 6. [Epub ahead of print] PubMed PMID: 24210571
  • Bansal D, Cost NG, Defoor WR Jr, Reddy PP, Minevich EA, Vanderbrink BA, Alam S, Sheldon CA, Noh PH. Infant robotic pyeloplasty: Comparison with an open cohort. J Pediatr Urol. 2013 Nov 9. [Epub ahead of print] PubMed PMID: 24268880
  • Cost NG. Robot assisted laparoscopic retroperitoneal lymph node dissection in testicular tumor. Urol Ann. 2013 Oct;5(4):226-7. PubMed PMID: 24311898
View All (119 Total) View Less

Professional Memberships

  • Alpha Omega Alpha (AOA), Member
  • American Association for Cancer Research (AACR), Associate Member
  • American College of Surgeons (ACS) , Resident Member
  • American Society of Clinical Oncology (ASCO), Associate Member
  • American Urological Association (AUA), Candidate Member
  • Children’s Oncology Group (COG), Associate Member
  • Endourological Society, Resident Member
  • International Society of Paediatric Surgical Oncology (IPSO), Member
  • Society for Adolescent and Young Adult Oncology (SAYAO), Member
  • Soci?t? Internationale d’Oncologie P?diatrique / International Society of Paediatric Oncology (SIOP), Member
  • Society for Pediatric Urology (SPU), Candidate Member
  • Society of Urologic Oncology (SUO), Candidate Member

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Colorado Fetal Care Center
13123 E 16th Ave
Aurora, CO 80045
855-413-3825

UCHealth Tony Grampsas Urologic Cancer Care Clinic - Anschutz Medical Campus
1665 Aurora Ct
1st Floor
Aurora, CO 80045
720-848-0170

Hospital Affiliation
  • University of Colorado Hospital
  • Children's Hospital Colorado
Center Affiliations

Specialty Information

Specialties
  • Pediatric Urology
  • Urology, Board Certification
  • Urologic Oncology
Conditions & Treatments
  • Cancers - Kidney Cancer
  • Cancers - Pediatric Cancer
  • Cancers - Sarcoma
  • Cancers - Urologic Cancer
  • Cancers - Testicular Cancer
  • Cancers - Cancer Surgery
  • Surgery - Urologic Surgery
  • Surgery - Robotic Surgery
  • Kidneys and Urinary System - Reconstructive Urology
  • Kidneys and Urinary System - Kidney Stones
  • Cancers
  • Kidneys and Urinary System
  • Surgery
Clinical Interests
My interest in testicular cancer has guided my training and career development. Testicular cancer is a disease that affects boys and men of all ages. For that reason, after completing my residency in Urology and Urologic Surgery, I pursued fellowship training in both urologic oncology (cancer treatment) and pediatric urology. This allows me to provide care to children, adolescents, and adults with testicular cancer at both “adult” and “pediatric” hospitals. I am involved with testicular cancer both as a clinician and as a researcher. My particular areas of focus include: •Robotic surgery for testicular cancer •Testicular cancer in adolescents •The Long-term effects of testicular-cancer treatment My additional clinical interests are in cancers and tumors in children, adolescents, and adults. Specifically kidney tumors (Wilms Tumor, Renal Cell Carcinoma (RCC), Angiomyolipomas(AML)), Testicular and Para-testicular tumors, and Pelvic Tumors (Rhabdomyosarcomas). This additionally includes patients with tumor predisposition syndromes such as von Hippel Lindau, Tuberous Sclerosis, and Birt-Hogg-Dube. My training in both urologic oncology and pediatric urology has prepared me to care for these patients of all ages and can see them either through Children's Hospital Colorado or through the University Hospital. I also am interested in the use of minimally invasive surgery (robotic-assisted laparoscopy, laparoscopy, single-site laparoscopy, and endoscopy) for all variety of urologic conditions. Within other areas of Pediatric Urology, I am interested in Ureteropelvic junction obstruction, Vesicoureteral reflux, and Urolithiasis (kidney stones).

Care Philosophy
I believe that by working in such a wonderful environment at the University of Colorado Anschutz Medical Campus, we can provide the most current therapy as well be involved in research to improve outcomes for patients with testicular cancer. My clinical philosophy for patient care is to first listen to the patient's concerns and needs. Then, I assess the patient's condition and previous testing and labs in order to explain my evaluation and offer my recommendations. I believe it is important to make sure the patient and family understand their condition as well as possible to enable us all to make the plan of care together, as a team. I am available to discuss your situation with you or your physician, so please feel free to contact me anytime at the e-mail address below. I look forward to the opportunity to work with you. Nicholas Cost, MD nicholas.cost@ucdenver.edu Selected Publications: 1.Cost NG, Lubahn JD, Adibi M, Romman A, Wickiser JE, Raj GV, Sagalowsky AI and Margulis V. Risk Stratification for Pubertal Children and Post-pubertal Adolescents with Clinical Stage I Testicular Non-Seminomatous Germ Cell Tumors. Journal of Urology, in press, accepted August 2013. 2.Cost NG, Lubahn JD, Adibi M, Romman A, Wickiser JE, Raj GV, Sagalowsky AI and Margulis V. A Comparison of Pediatric, Adolescent and Adult Testicular Germ Cell Malignancy. Pediatric Blood and Cancer, e-Pub September 17, 2013. 3.Cost NG. Testicular Germ Cell Tumors: Current Concepts and Management Strategies. Minerva Urologica e Nefrologica. 2013: 65(2):133-155. 4.Cost NG, DaJusta DG, Granberg CF, Cooksey RM, Laborde CE, Wickiser JE and Gargollo PC. Robotic Assisted Laparoscopic Retroperitoneal Lymph Node Dissection in an Adolescent Population. Journal of Endourology. 2012; 26(6):635-40. 5.Cost NG, Adibi M, Lubahn JD, Romman A, Raj GV, Sagalowsky AI and Margulis V. Effect of Testicular Germ Cell Tumor Therapy on Renal Function. Urology. 2012; 80(3):641-8. 6.Cost NG, Cost CR, Geller JI and DeFoor WR. Adolescent Urologic Oncology: Current Issues and Future Directions. Urologic Oncology: Seminars and Original Investigations, e-Pub November 7, 2012. 7.Applegate KE and Cost NG. Image Gently: A Campaign to Reduce Children’s and Adolescents’ Risk for Cancer During Adulthood. Journal of Adolescent Health. 2013; 52(5 Suppl):S93-7.

Personal Interests
Outside of work I enjoy spending time with my wife, my son, and family. We love to travel and experience foreign languages and cultures, specifically the time we spend in Italy. I enjoy being active and being in the wonderful Colorado outdoors (Golf, Skiing, Basketball, Soccer, Running), but also try to find time to relax and enjoy reading, both fiction and non-fiction.

Public Speaking
Yes
Kidney Cancer; Testicular Cancer; Pediatric, Adolescent and Young Adult Urologic Oncology

General Information

Medical Schools:
  • MD, Emory University School of Medicine (2005)
Undergraduate Schools:
  • BS, Vanderbilt University (TN) (2001)
Internships:
  • University of Texas Southwestern Medical School Program (2006)
Residency Programs:
  • University of Texas Southwestern Medical School Program, Chief Resident, Urology (2010)
Fellowships:
  • University of Texas Southwestern Medical School Program, Urologic Oncology (2011)
  • Cincinnati Children's Hospital Medical Center/University of Cincinnati College of Medicine Program, Pediatric Urology (2013)
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Languages: English, Italian
Department: Surgery-Urology
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