Kristen Boyle, PhD
Assistant Professor, Pediatrics-Nutrition

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Graduate Schools :
  • MS, Ohio University (2005)
  • PhD, East Carolina University (2009)
Undergraduate School:
  • BS, University of Massachusetts–Amherst (MA) (2001)
Languages: English
Department: Pediatrics-Nutrition

Recognition & Awards

  • Award Recipient, NIH Loan Repayment Program, (2014)
  • Women’s Health Research Day Poster Award, University of Colorado Center for Women's Health Research, (2013)
  • Travel Award , Seahorse Bioscience , (2012)
  • Award Recipient, NIH Loan Repayment Program , (2011)
  • Department of Biological Sciences Travel Grant, Ohio University, (2003)
  • Commonwealth Scholar, University of Massachusetts, Amherst, (2001)
  • Academic Scholarship, State of Connecticut , (1996)
  • Academic Scholarship, Commonwealth of Massachusetts , (1996)

Publications

  • Bruce KD, Gorkhali S, Given K, Coates AM, Boyle KE, Macklin WB, Eckel RH. Lipoprotein Lipase Is a Feature of Alternatively-Activated Microglia and May Facilitate Lipid Uptake in the CNS During Demyelination. Front Mol Neurosci. 2018;11:57. PubMed PMID: 29599706
  • Reusch JEB, Kumar TR, Regensteiner JG, Zeitler PS. Identifying the Critical Gaps in Research on Sex Differences in Metabolism Across the Life Span. Endocrinology. 2018 Jan 1;159(1):9-19. PubMed PMID: 29300998
  • Boyle KE, Patinkin ZW, Shapiro ALB, Bader C, Vanderlinden L, Kechris K, Janssen RC, Ford RJ, Smith BK, Steinberg GR, Davidson EJ, Yang IV, Dabelea D, Friedman JE. Maternal obesity alters fatty acid oxidation, AMPK activity, and associated DNA methylation in mesenchymal stem cells from human infants. Mol Metab. 2017 Nov;6(11):1503-1516. PubMed PMID: 29107296
  • Baker PR 2nd, Patinkin Z, Shapiro AL, De La Houssaye BA, Woontner M, Boyle KE, Vanderlinden L, Dabelea D, Friedman JE. Maternal obesity and increased neonatal adiposity correspond with altered infant mesenchymal stem cell metabolism. JCI Insight. 2017 Nov 2;2(21). [Epub ahead of print] PubMed PMID: 29093265
  • Cavalli G, Justice JN, Boyle KE, D'Alessandro A, Eisenmesser EZ, Herrera JJ, Hansen KC, Nemkov T, Stienstra R, Garlanda C, Mantovani A, Seals DR, Dagna L, Joosten LA, Ballak DB, Dinarello CA. Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance. Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):2313-2318. PubMed PMID: 28193888
  • Boyle KE, Friedman JE, Janssen RC, Underkofler C, Houmard JA, Rasouli N. Metabolic Inflexibility with Obesity and the Effects of Fenofibrate on Skeletal Muscle Fatty Acid Oxidation. Horm Metab Res. 2017 Jan;49(1):50-57. PubMed PMID: 28103623
  • Shapiro AL, Boyle KE, Dabelea D, Patinkin ZW, De la Houssaye B, Ringham BM, Glueck DH, Barbour LA, Norris JM, Friedman JE. Nicotinamide Promotes Adipogenesis in Umbilical Cord-Derived Mesenchymal Stem Cells and Is Associated with Neonatal Adiposity: The Healthy Start BabyBUMP Project. PLoS One. 2016 Jul 14;11(7):e0159575. PubMed PMID: 27414406
  • Boyle KE, Friedman JE, Janssen RC, Underkofler C, Houmard JA, Rasouli N. Metabolic Inflexibility with Obesity and the Effects of Fenofibrate on Skeletal Muscle Fatty Acid Oxidation. Horm Metab Res. 2016 Aug 2. [Epub ahead of print] PubMed PMID: 27485593
  • Shapiro AL, Boyle KE, Dabelea D, Patinkin ZW, De la Houssaye B, Ringham BM, Glueck DH, Barbour LA, Norris JM, Friedman JE. Nicotinamide Promotes Adipogenesis in Umbilical Cord-Derived Mesenchymal Stem Cells and Is Associated with Neonatal Adiposity: The Healthy Start BabyBUMP Project. PLoS One. 2016 Jul 14;11(7):e0159575. PubMed PMID: 27414406
  • Boyle KE, Patinkin ZW, Shapiro AL, Baker PR 2nd, Dabelea D, Friedman JE. Mesenchymal Stem Cells from Infants Born to Obese Mothers Exhibit Greater Potential for Adipogenesis: The Healthy Start BabyBUMP Project. Diabetes. 2015 Dec 2. [Epub ahead of print] PubMed PMID: 26631736
  • Schlaepfer IR, Glodé LM, Hitz CA, Pac CT, Boyle KE, Maroni P, Deep G, Agarwal R, Lucia SM, Cramer SD, Serkova NJ, Eckel RH. Inhibition of Lipid Oxidation Increases Glucose Metabolism and Enhances 2-Deoxy-2-[(18)F]Fluoro-D-Glucose Uptake in Prostate Cancer Mouse Xenografts. Mol Imaging Biol. 2015 Jan 6. [Epub ahead of print] PubMed PMID: 25561013
  • Boyle KE, Patinkin ZW, Shapiro AL, Baker PR 2nd, Dabelea D, Friedman JE. Mesenchymal Stem Cells from Infants Born to Obese Mothers Exhibit Greater Potential for Adipogenesis: The Healthy Start BabyBUMP Project. Diabetes. 2015 Dec 2. [Epub ahead of print] PubMed PMID: 26631736
  • Baker PR 2nd, Boyle KE, Koves TR, Ilkayeva OR, Muoio DM, Houmard JA, Friedman JE. Metabolomic analysis reveals altered skeletal muscle amino acid and fatty acid handling in obese humans. Obesity (Silver Spring). 2015 May;23(5):981-8. PubMed PMID: 25864501
  • Schlaepfer IR, Glodé LM, Hitz CA, Pac CT, Boyle KE, Maroni P, Deep G, Agarwal R, Lucia SM, Cramer SD, Serkova NJ, Eckel RH. Inhibition of Lipid Oxidation Increases Glucose Metabolism and Enhances 2-Deoxy-2-[(18)F]Fluoro-D-Glucose Uptake in Prostate Cancer Mouse Xenografts. Mol Imaging Biol. 2015 Jan 6. [Epub ahead of print] PubMed PMID: 25561013
  • Boyle KE, Hwang H, Janssen RC, DeVente JM, Barbour LA, Hernandez TL, Mandarino LJ, Lappas M, Friedman JE. Gestational diabetes is characterized by reduced mitochondrial protein expression and altered calcium signaling proteins in skeletal muscle. PLoS One. 2014;9(9):e106872. PubMed PMID: 25216282
  • Boyle KE, Hwang H, Janssen RC, DeVente JM, Barbour LA, Hernandez TL, Mandarino LJ, Lappas M, Friedman JE. Gestational diabetes is characterized by reduced mitochondrial protein expression and altered calcium signaling proteins in skeletal muscle. PLoS One. 2014;9(9):e106872. PubMed PMID: 25216282
  • Newsom SA, Boyle KE, Friedman JE. Sirtuin 3: A major control point for obesity-related metabolic diseases?. Drug Discov Today Dis Mech. 2013 Jun 1;10(1-2):e35-e40. PubMed PMID: 23997790
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Professional Memberships

  • The Obesity Society, Member
  • American Diabetes Association, Member
  • American Heart Association (AHA), Member

Practice Locations

Hospital Affiliation
  • Children's Hospital Colorado
Center Affiliations
Public Speaking
Yes

General Information

Graduate Schools:
  • MS, Ohio University (2005)
  • PhD, East Carolina University (2009)
Undergraduate Schools:
  • BS, University of Massachusetts–Amherst (MA) (2001)
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Languages: English
Department: Pediatrics-Nutrition
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