Anna Malykhina, PhD
Professor, Surgery-Urology

Photo
Department: Surgery-Urology

Publications

  • Feng B, Malykhina AP. Editorial: Emerging trends in abdominal and pelvic pain. Front Pain Res (Lausanne). 2023;4:1254682. PubMed PMID: 37711988
  • Iguchi N, Dönmez MI, Malykhina AP, Wilcox DT. Anti-fibrotic effect of tocotrienols for bladder dysfunction due to partial bladder outlet obstruction. Investig Clin Urol. 2023 Mar;64(2):189-196. PubMed PMID: 36882179
  • Iguchi N, Hecht SL, Gao D, Wilcox DT, Malykhina AP, Cost NG. Sexual dimorphic impacts of systemic vincristine on lower urinary tract function. Sci Rep. 2022 Mar 24;12(1):5113. PubMed PMID: 35332157
  • Xie AX, Iguchi N, Clarkson TC, Malykhina AP. Pharmacogenetic inhibition of lumbosacral sensory neurons alleviates visceral hypersensitivity in a mouse model of chronic pelvic pain. PLoS One. 2022;17(1):e0262769. PubMed PMID: 35077502
  • Clarkson TC, Iguchi N, Xie AX, Malykhina AP. Differential transcriptomic changes in the central nervous system and urinary bladders of mice infected with a coronavirus. PLoS One. 2022;17(12):e0278918. PubMed PMID: 36490282
  • Iguchi N, Hecht SL, Gao D, Wilcox DT, Malykhina AP, Cost NG. Sexual dimorphic impacts of systemic vincristine on lower urinary tract function. Sci Rep. 2022 Mar 24;12(1):5113. PubMed PMID: 35332157
  • Xie AX, Iguchi N, Clarkson TC, Malykhina AP. Pharmacogenetic inhibition of lumbosacral sensory neurons alleviates visceral hypersensitivity in a mouse model of chronic pelvic pain. PLoS One. 2022;17(1):e0262769. PubMed PMID: 35077502
  • Hecht SL, Quach A, Gao D, Brazell A, Beltran G, Holbrook S, Gore L, Iguchi N, Malykhina A, Wilcox D, Cost NG. A prospective survey study of lower urinary tract dysfunction in childhood cancer survivors after vincristine and/or doxorubicin chemotherapy. Pediatr Blood Cancer. 2021 Oct;68(10):e29226. PubMed PMID: 34245214
  • Soriano A, Allen A, Malykhina AP, Andy U, Harvie H, Arya L. Relationship of Pain Catastrophizing With Urinary Biomarkers in Women With Bladder Pain Syndrome. Female Pelvic Med Reconstr Surg. 2021 Dec 1;27(12):746-752. PubMed PMID: 33787562
  • Lloyd GL, Wiesen B, Atwell M, Malykhina A. Marijuana, Alcohol, and ED: Correlations with LUTS/BPH. Curr Urol Rep. 2021 Feb 8;22(4):21. PubMed PMID: 33554319
  • Iguchi N, Carrasco A Jr, Xie AX, Pineda RH, Malykhina AP, Wilcox DT. Functional constipation induces bladder overactivity associated with upregulations of Htr2 and Trpv2 pathways. Sci Rep. 2021 Jan 13;11(1):1149. PubMed PMID: 33441874
  • Smith AL, Weissbart SJ, Hartigan SM, Bilello M, Newman DK, Wein AJ, Malykhina AP, Erus G, Fan Y. Association between urinary symptom severity and white matter plaque distribution in women with multiple sclerosis. Neurourol Urodyn. 2020 Jan;39(1):339-346. PubMed PMID: 31691357
  • Xie AX, Madayag A, Minton SK, McCarthy KD, Malykhina AP. Sensory satellite glial Gq-GPCR activation alleviates inflammatory pain via peripheral adenosine 1 receptor activation. Sci Rep. 2020 Aug 25;10(1):14181. PubMed PMID: 32843670
  • Soriano A, Andy U, Hassani D, Whitmore K, Harvie H, Malykhina AP, Arya L. Relationship of Bladder Pain With Clinical and Urinary Markers of Neuroinflammation in Women With Urinary Urgency Without Urinary Incontinence. Female Pelvic Med Reconstr Surg. 2020 Oct 1. [Epub ahead of print] PubMed PMID: 33009262
  • Smith AL, Weissbart SJ, Hartigan SM, Bilello M, Newman DK, Wein AJ, Malykhina AP, Erus G, Fan Y. Association between urinary symptom severity and white matter plaque distribution in women with multiple sclerosis. Neurourol Urodyn. 2020 Jan;39(1):339-346. PubMed PMID: 31691357
  • Lloyd G.L., Wiesen B., Atwell M., Malykhina A., Marijuana, Alcohol, and ED: Correlations with LUTS/BPH". Current Urology Reports (in Press)
  • Nedumaran B, Pineda RH, Rudra P, Lee S, Malykhina AP. Association of genetic polymorphisms in the pore domains of mechano-gated TREK-1 channel with overactive lower urinary tract symptoms in humans. Neurourol Urodyn. 2019 Jan;38(1):144-150. PubMed PMID: 30350878
  • Lee S, Nedumaran B, Hypolite J, Caldwell B, Rudolph MC, Malykhina AP. Differential neurodegenerative phenotypes are associated with heterogeneous voiding dysfunction in a coronavirus-induced model of multiple sclerosis. Sci Rep. 2019 Jul 26;9(1):10869. PubMed PMID: 31350464
  • Iguchi N, Dönmez MI, Carrasco A Jr, Wilcox DT, Pineda RH, Malykhina AP, Cost NG. Doxorubicin induces detrusor smooth muscle impairments through myosin dysregulation, leading to a risk of lower urinary tract dysfunction. Am J Physiol Renal Physiol. 2019 Jul 1;317(1):F197-F206. PubMed PMID: 31066574
  • Pineda RH, Hypolite J, Lee S, Carrasco A Jr, Iguchi N, Meacham RB, Malykhina AP. Altered detrusor contractility and voiding patterns in mice lacking the mechanosensitive TREK-1 channel. BMC Urol. 2019 May 21;19(1):40. PubMed PMID: 31113422
  • Nedumaran B, Pineda RH, Rudra P, Lee S, Malykhina AP. Association of genetic polymorphisms in the pore domains of mechano-gated TREK-1 channel with overactive lower urinary tract symptoms in humans. Neurourol Urodyn. 2019 Jan;38(1):144-150. PubMed PMID: 30350878
  • Iguchi N, Malykhina AP, Wilcox DT. Early life voiding dysfunction leads to lower urinary tract dysfunction through alteration of muscarinic and purinergic signaling in the bladder. Am J Physiol Renal Physiol. 2018 Aug 8. [Epub ahead of print] PubMed PMID: 30089034
  • Nedumaran B, Rudra P, Gaydos J, Kumar S, Meacham RB, Burnham EL, Malykhina AP. Impact of Regular Cannabis Use on Biomarkers of Lower Urinary Tract Function. Urology. 2017 Nov;109:223.e9-223.e16. PubMed PMID: 28827195
  • Iguchi N, Dönmez MI, Malykhina AP, Carrasco A Jr, Wilcox DT. Preventative effects of a HIF inhibitor, 17-DMAG, on partial bladder outlet obstruction-induced bladder dysfunction. Am J Physiol Renal Physiol. 2017 Nov 1;313(5):F1149-F1160. PubMed PMID: 28768664
  • Pineda RH, Nedumaran B, Hypolite J, Pan XQ, Wilson S, Meacham RB, Malykhina AP. Altered expression and modulation of the two-pore-domain (K(2P)) mechanogated potassium channel TREK-1 in overactive human detrusor. Am J Physiol Renal Physiol. 2017 Aug 1;313(2):F535-F546. PubMed PMID: 28539337
  • Lee S, Malykhina AP. Neuro-tracing approach to study kidney innervation: a technical note. Kidney Res Clin Pract. 2017 Mar;36(1):86-94. PubMed PMID: 28393001
  • Malykhina AP. How the brain controls urination. Elife. 2017 Dec 4;6. PubMed PMID: 29199949
  • Richter HE, Moalli P, Amundsen CL, Malykhina AP, Wallace D, Rogers R, Myers D, Paraiso M, Albo M, Shi H, Nolen T, Meikle S, Word RA. Urinary Biomarkers in Women with Refractory Urgency Urinary Incontinence Randomized to Sacral Neuromodulation versus OnabotulinumtoxinA Compared to Controls. J Urol. 2017 Jun;197(6):1487-1495. PubMed PMID: 28089729
  • Lee S, Carrasco A Jr, Meacham RB, Malykhina AP. Transurethral Instillation Procedure in Adult Male Mouse. J Vis Exp. 2017 Nov 2;(129). PubMed PMID: 29155777
  • Pennycuff JF, Schutte SC, Hudson CO, Karp DR, Malykhina AP, Northington GM. Urinary neurotrophic peptides in postmenopausal women with and without overactive bladder. Neurourol Urodyn. 2017 Mar;36(3):740-744. PubMed PMID: 27062604
  • Malykhina AP, Brodie KE, Wilcox DT. Genitourinary and gastrointestinal co-morbidities in children: The role of neural circuits in regulation of visceral function. J Pediatr Urol. 2017 Apr;13(2):177-182. PubMed PMID: 28392009
  • Lamarre NS, Braverman AS, Malykhina AP, Barbe MF, Ruggieri MR Sr. Alterations in nerve-evoked bladder contractions in a coronavirus-induced mouse model of multiple sclerosis. PLoS One. 2014;9(10):e109314. PubMed PMID: 25310403
  • Clarkson T.C., Iguchi N., Xie A.X, Malykhina A.P. Differential transcriptomic changes in the central nervous system and neurogenic bladders of mice infected with a coronavirus. PLOS One
View All (33 Total) View Less

General Information

Department: Surgery-Urology
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

Update My Profile
;