Laura Sherlock, MD
Assistant Professor, Pediatrics-Neonatology

Publications

• Pharmacology in Neonatal Care
• Sherlock LG, Krebs NF. Small and mighty: Micronutrients at the intersection of neonatal immunity and infection. Neoreviews
• Cookson MW, Sherlock LG. Sex differences in endothelial cell function: an evolving explanation of sex differences in preterm infant pulmonary outcomes. Am J Physiol Heart Circ Physiol. 2023 May 1;324(5):H579-H580. PubMed PMID: 36897750
• Sherlock LG, Krebs NF. Small and Mighty: Micronutrients at the Intersection of Neonatal Immunity and Infection. Neoreviews. 2023 Mar 1;24(3):e158-e174. PubMed PMID: 36854844
• McCarthy WC, Sherlock LG, Grayck MR, Zheng L, Lacayo OA, Solar M, Orlicky DJ, Dobrinskikh E, Wright CJ. Innate Immune Zonation in the Liver: NF-?B (p50) Activation and C-Reactive Protein Expression in Response to Endotoxemia Are Zone Specific. J Immunol. 2023 May 1;210(9):1372-1385. PubMed PMID: 36946778
• McCulley DJ, Jensen EA, Sucre JMS, McKenna S, Sherlock LG, Dobrinskikh E, Wright CJ. Racing against time: leveraging preclinical models to understand pulmonary susceptibility to perinatal acetaminophen exposures. Am J Physiol Lung Cell Mol Physiol. 2022 Jul 1;323(1):L1-L13. PubMed PMID: 35503238
• Sherlock LG, Balasubramaniyan D, Zheng L, Grayck M, McCarthy WC, De Dios RC, Zarate MA, Orlicky DJ, De Dios R, Wright CJ. APAP-Induced I?Bß/NF?B Signaling Drives Hepatic Il6 Expression and Associated Sinusoidal Dilation. Toxicol Sci. 2022 Jan 24;185(2):158-169. PubMed PMID: 34726736
• Roberts DS, Sherlock LG, Posey JN, Archambault JL, Nozik ES, Delaney CA. Serotonin-deficient neonatal mice are not protected against the development of experimental bronchopulmonary dysplasia or pulmonary hypertension. Physiol Rep. 2022 Oct;10(19):e15482. PubMed PMID: 36200294
• Solar M, Grayck MR, McCarthy WC, Zheng L, Lacayo OA, Sherlock LG, Zhou R, Orlicky DJ, Wright CJ. Absence of I?Bß/NF?B signaling does not attenuate acetaminophen-induced hepatic injury. Anat Rec (Hoboken). 2022 Nov 25. [Epub ahead of print] PubMed PMID: 36426684
• Sherlock LG et al. Neonatal selenium deficiency decreases selenoproteins in the lung and impairs pulmonary alveolar development. Antioxidants
• Dobrinskikh E, Sherlock LG, Orlicky DJ, Zheng L, De Dios R, Balasubramaniyan D, Sizemore T, Butler B, Wright CJ. The developing murine lung is susceptible to acetaminophen toxicity. Am J Physiol Lung Cell Mol Physiol. 2021 May 1;320(5):L969-L978. PubMed PMID: 33759579
• Dobrinskikh E, Al-Juboori S, Zarate M, Zheng L, de Dios R, Balasubramaniyan D, Sherlock LG, Orlicky D, Wright CJ. Pulmonary implications of acetaminophen exposures independent of hepatic toxicity. Am J Physiol Lung Cell Mol Physiol. 2021 Sep 29. [Epub ahead of print] PubMed PMID: 34585971
• Sherlock LG, Balasubramaniyan D, Zheng L, Zarate M, Sizemore T, Delaney C, Tipple TE, Wright CJ, Nozik-Grayck E. Neonatal Selenoenzyme Expression Is Variably Susceptible to Duration of Maternal Selenium Deficiency. Antioxidants (Basel). 2021 Feb 14;10(2). PubMed PMID: 33672905
• Zarate MA, De Dios RK, Balasubramaniyan D, Zheng L, Sherlock LG, Rozance PJ, Wright CJ. The Acute Hepatic NF-?B-Mediated Proinflammatory Response to Endotoxemia Is Attenuated in Intrauterine Growth-Restricted Newborn Mice. Front Immunol. 2021;12:706774. PubMed PMID: 34539638
• Sherlock LG, Wright CJ, Kinsella JP, Delaney C. Inhaled nitric oxide use in neonates: Balancing what is evidence-based and what is physiologically sound. Nitric Oxide. 2020 Feb 1;95:12-16. PubMed PMID: 31866361
• White A, Mukherjee P, Stremming J, Sherlock LG, Reynolds RM, Smith D, Asturias EJ, Grover TR, Dietz RM. Neonates Hospitalized with Community-Acquired SARS-CoV-2 in a Colorado Neonatal Intensive Care Unit. Neonatology. 2020 Jun 4;:1-5. [Epub ahead of print] PubMed PMID: 32498065
• Sherlock LG, Sjostrom K, Sian L, Delaney C, Tipple TE, Krebs NF, Nozik-Grayck E, Wright CJ. Hepatic-Specific Decrease in the Expression of Selenoenzymes and Factors Essential for Selenium Processing After Endotoxemia. Front Immunol. 2020;11:595282. PubMed PMID: 33224150
• Wright CJ, Sherlock LG, Sahni R, Polin RA. Preventing Continuous Positive Airway Pressure Failure: Evidence-Based and Physiologically Sound Practices from Delivery Room to the Neonatal Intensive Care Unit. Clin Perinatol. 2018 Jun;45(2):257-271. PubMed PMID: 29747887
• McGraw MD, Sherlock LG, Bailey KL, Abman SH. Developmental Origins of Chronic Lung Diseases. Mechanical Stretch, Micro-RNAs, and Hydrogels. Am J Respir Cell Mol Biol. 2018 Aug;59(2):267-270. PubMed PMID: 29641225
• Sherlock LG, Trumpie A, Hernandez-Lagunas L, McKenna S, Fisher S, Bowler R, Wright CJ, Delaney C, Nozik-Grayck E. Redistribution of Extracellular Superoxide Dismutase Causes Neonatal Pulmonary Vascular Remodeling and PH but Protects Against Experimental Bronchopulmonary Dysplasia. Antioxidants (Basel). 2018 Mar 14;7(3). PubMed PMID: 29538340
• Delaney C, Sherlock L, Fisher S, Maltzahn J, Wright C, Nozik-Grayck E. Serotonin 2A receptor inhibition protects against the development of pulmonary hypertension and pulmonary vascular remodeling in neonatal mice. Am J Physiol Lung Cell Mol Physiol. 2018 May 1;314(5):L871-L881. PubMed PMID: 29345193