Emily Su, MD, MSCI
Professor, OB-GYN-Basic Repro Science

Professional Titles

• Professor

Recognition & Awards

• Fellow, American Gynecological and Obstetrical Society (AGOS) (2022)
• Mentor of the Year Award, American College of Obstetricians and Gynecologists District VIII (2019)
• The IFPA Early Career Research Award, International Federation of Placenta Association (2016)
• President's Achievement Award, Society for Reproductive Investigation (2015)
• AOA Member, Alpha Omega Alpha Honor Medical Society (2000)
• The Harry Garber, MD, Distinguished Alumnus Award, University of Illinois at Chicago College of Medicine (2000)

Research Interests

Publications

• Sayres L, Flockton AR, Ji S, Rey Diaz C, Gumina DL, Su EJ. Angiogenic Function of Human Placental Endothelial Cells in Severe Fetal Growth Restriction Is Not Rescued by Individual Extracellular Matrix Proteins. Cells. 2023 Sep 23;12(19). PubMed PMID: 37830553
• Bailey EJ, Tita ATN, Leach J, Boggess K, Dugoff L, Sibai B, Lawrence K, Hughes BL, Bell J, Aagaard K, Edwards RK, Gibson K, Haas DM, Plante L, Metz TD, Casey BM, Esplin S, Longo S, Hoffman M, Saade GR, Foroutan J, Tuuli MG, Owens MY, Simhan HN, Frey HA, Rosen T, Palatnik A, Baker S, August P, Reddy UM, Kinzler W, Su EJ, Krishna I, Nguyen N, Norton ME, Skupski D, El-Sayed YY, Ogunyemi D, Galis ZS, Harper L, Ambalavanan N, Oparil S, Kuo HC, Szychowski JM, Hoppe K. Perinatal Outcomes Associated With Management of Stage 1 Hypertension. Obstet Gynecol. 2023 Dec 1;142(6):1395-1404. PubMed PMID: 37769314
• Su EJ. Scaling the EVERREST of severe, early-onset fetal growth restriction. J Clin Invest. 2023 Sep 15;133(18). PubMed PMID: 37712422
• Goulding AN, Antoniewicz L, Leach JM, Boggess K, Dugoff L, Sibai B, Lawrence K, Hughes BL, Bell J, Edwards RK, Gibson K, Haas DM, Plante L, Metz TD, Casey B, Esplin S, Longo S, Hoffman M, Saade GR, Hoppe KK, Foroutan J, Tuuli M, Owens MY, Simhan HN, Frey H, Rosen T, Palatnik A, Baker S, Reddy UM, Kinzler W, Su E, Krishna I, Nguyen N, Norton ME, Skupski D, El-Sayed YY, Ogunyemi D, Harper LM, Ambalavanan N, Oparil S, Szychowski JM, Tita AT. Breastfeeding initiation and duration among people with mild chronic hypertension: a secondary analysis of the Chronic Hypertension and Pregnancy trial. Am J Obstet Gynecol MFM. 2023 Sep;5(9):101086. PubMed PMID: 37437694
• Gumina DL, Su EJ. Mechanistic insights into the development of severe fetal growth restriction. Clin Sci (Lond). 2023 Apr 26;137(8):679-695. PubMed PMID: 37186255
• Gumina DL, Ji S, Flockton A, McPeak K, Stich D, Moldovan R, Su EJ. Dysregulation of integrin avß3 and a5ß1 impedes migration of placental endothelial cells in fetal growth restriction. Development. 2022 Oct 1;149(19):dev200717. PubMed PMID: 36193846
• Costantine MM, Sibai B, Bombard AT, Sarno M, West H, Haas DM, Tita AT, Paidas MJ, Clark EAS, Boggess K, Grotegut C, Grobman W, Su EJ, Burd I, Saade G, Chavez MR, Paglia MJ, Merriam A, Torres C, Habli M, Macones G, Wen T, Bofill J, Palatnik A, Edwards RK, Haeri S, Oberoi P, Mazloom A, Cooper M, Lockton S, Hankins GD. Performance of a Multianalyte 'Rule-Out' Assay in Pregnant Individuals With Suspected Preeclampsia. Hypertension. 2022 Jul;79(7):1515-1524. PubMed PMID: 35545947
• Heath-Freudenthal A, Toledo-Jaldin L, von Alvensleben I, Lazo-Vega L, Mizutani R, Stalker M, Yasini H, Mendizabal F, Dorado Madera J, Mundo W, Castro-Monrroy M, Houck JA, Moreno-Aramayo A, Miranda-Garrido V, Su EJ, Giussani DA, Abman SH, Moore LG, Julian CG. Vascular Disorders of Pregnancy Increase Susceptibility to Neonatal Pulmonary Hypertension in High-Altitude Populations. Hypertension. 2022 Jun;79(6):1286-1296. PubMed PMID: 35437031
• Tita AT, Szychowski JM, Boggess K, Dugoff L, Sibai B, Lawrence K, Hughes BL, Bell J, Aagaard K, Edwards RK, Gibson K, Haas DM, Plante L, Metz T, Casey B, Esplin S, Longo S, Hoffman M, Saade GR, Hoppe KK, Foroutan J, Tuuli M, Owens MY, Simhan HN, Frey H, Rosen T, Palatnik A, Baker S, August P, Reddy UM, Kinzler W, Su E, Krishna I, Nguyen N, Norton ME, Skupski D, El-Sayed YY, Ogunyemi D, Galis ZS, Harper L, Ambalavanan N, Geller NL, Oparil S, Cutter GR, Andrews WW. Treatment for Mild Chronic Hypertension during Pregnancy. N Engl J Med. 2022 May 12;386(19):1781-1792. PubMed PMID: 35363951
• Ji S, Gumina D, McPeak K, Moldovan R, Post MD, Su EJ. Human placental villous stromal extracellular matrix regulates fetoplacental angiogenesis in severe fetal growth restriction. Clin Sci (Lond). 2021 May 14;135(9):1127-1143. PubMed PMID: 33904582
• Ouyang Y, Bagalkot T, Fitzgerald W, Sadovsky E, Chu T, Martínez-Marchal A, Brieño-Enríquez M, Su EJ, Margolis L, Sorkin A, Sadovsky Y. Term Human Placental Trophoblasts Express SARS-CoV-2 Entry Factors ACE2, TMPRSS2, and Furin. mSphere. 2021 Apr 14;6(2). PubMed PMID: 33853873
• Markenson GR, Saade GR, Laurent LC, Heyborne KD, Coonrod DV, Schoen CN, Baxter JK, Haas DM, Longo S, Grobman WA, Sullivan SA, Major CA, Wheeler SM, Pereira LM, Su EJ, Boggess KA, Hawk AF, Crockett AH, Fox AC, Polpitiya A, Fleischer TC, Critchfield GC, Burchard J, Boniface JJ, Lam GK. Performance of a proteomic preterm delivery predictor in a large independent prospective cohort. Am J Obstet Gynecol MFM. 2020 Aug;2(3):100140. PubMed PMID: 33345877
• Ji S, Xin H, Su EJ. Overexpression of the aryl hydrocarbon receptor nuclear translocator partially rescues fetoplacental angiogenesis in severe fetal growth restriction. Clin Sci (Lond). 2019 Jun 28;133(12):1353-1365. PubMed PMID: 31189688
• Ji S, Xin H, Li Y, Su EJ. FMS-like tyrosine kinase 1 (FLT1) is a key regulator of fetoplacental endothelial cell migration and angiogenesis. Placenta. 2018 Oct;70:7-14. PubMed PMID: 30316329
• Li Y, Lorca RA, Su EJ. Molecular and cellular underpinnings of normal and abnormal human placental blood flows. J Mol Endocrinol. 2018 Jan;60(1):R9-R22. PubMed PMID: 29097590
• Gumina DL, Su EJ. Endothelial Progenitor Cells of the Human Placenta and Fetoplacental Circulation: A Potential Link to Fetal, Neonatal, and Long-term Health. Front Pediatr. 2017;5:41. PubMed PMID: 28361046
• Mestan KK, Gotteiner N, Porta N, Grobman W, Su EJ, Ernst LM. Cord Blood Biomarkers of Placental Maternal Vascular Underperfusion Predict Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension. J Pediatr. 2017 Jun;185:33-41. PubMed PMID: 28162769
• Palatnik A, Xin H, Su EJ. Dichotomous effects of aryl hydrocarbon receptor (AHR) activation on human fetoplacental endothelial cell function. Placenta. 2016 Aug;44:61-8. PubMed PMID: 27452439
• Blundell C, Tess ER, Schanzer AS, Coutifaris C, Su EJ, Parry S, Huh D. A microphysiological model of the human placental barrier. Lab Chip. 2016 Aug 2;16(16):3065-73. PubMed PMID: 27229450
• Su EJ, Xin H, Yin P, Dyson M, Coon J, Farrow KN, Mestan KK, Ernst LM. Impaired fetoplacental angiogenesis in growth-restricted fetuses with abnormal umbilical artery doppler velocimetry is mediated by aryl hydrocarbon receptor nuclear translocator (ARNT). J Clin Endocrinol Metab. 2015 Jan;100(1):E30-40. PubMed PMID: 25343232
• Su EJ. Role of the fetoplacental endothelium in fetal growth restriction with abnormal umbilical artery Doppler velocimetry. Am J Obstet Gynecol. 2015 Oct;213(4 Suppl):S123-30. PubMed PMID: 26428491
• Monsivais D, Dyson MT, Yin P, Coon JS, Navarro A, Feng G, Malpani SS, Ono M, Ercan CM, Wei JJ, Pavone ME, Su E, Bulun SE. ERß- and prostaglandin E2-regulated pathways integrate cell proliferation via Ras-like and estrogen-regulated growth inhibitor in endometriosis. Mol Endocrinol. 2014 Aug;28(8):1304-15. PubMed PMID: 24992181
• Mestan KK, Check J, Minturn L, Yallapragada S, Farrow KN, Liu X, Su E, Porta N, Gotteiner N, Ernst LM. Placental pathologic changes of maternal vascular underperfusion in bronchopulmonary dysplasia and pulmonary hypertension. Placenta. 2014 Aug;35(8):570-4. PubMed PMID: 24906549
• Voller SB, Chock S, Ernst LM, Su E, Liu X, Farrow KN, Mestan KK. Cord blood biomarkers of vascular endothelial growth (VEGF and sFlt-1) and postnatal growth: a preterm birth cohort study. Early Hum Dev. 2014 Apr;90(4):195-200. PubMed PMID: 24480606

Professional Memberships

• American College of Obstetrics and Gynecology, Member
• Society for Maternal-Fetal Medicine, Member
• Society for Reproductive Investigation, Member