Prateeti Khazanie, MD
Associate Professor, Medicine-Cardiology

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Medical School:
  • MD, Duke University School of Medicine (2006)
Graduate School :
  • MPH, University of North Carolina at Chapel Hill (2006)
Undergraduate School:
  • BA, Duke University (NC) (2000)
Internship:
  • Stanford Hospital and Clinics Program (2007)
Residency:
  • Stanford Hospital and Clinics Program, Chief Resident, Internal Medicine (2010)
Fellowships:
  • Duke University Hospital Program, Cardiology (2014)
  • Duke University Hospital Program, Advanced Heart Failure and Transplant Cardiology (2015)
Department: Medicine-Cardiology

Publications

  • Morris AA, Khazanie P, Drazner MH, Albert NM, Breathett K, Cooper LB, Eisen HJ, O'Gara P, Russell SD. Guidance for Timely and Appropriate Referral of Patients With Advanced Heart Failure: A Scientific Statement From the American Heart Association. Circulation. 2021 Oct 12;144(15):e238-e250. PubMed PMID: 34503343
  • Knoepke CE, Chaussee EL, Matlock DD, Thompson JS, McIlvennan CK, Ambardekar AV, Schaffer EM, Khazanie P, Scherer L, Arnold RM, Allen LA. Changes over Time in Patient Stated Values and Treatment Preferences Regarding Aggressive Therapies: Insights from the DECIDE-LVAD Trial. Med Decis Making. 2021 Jul 23;:272989X211028234. [Epub ahead of print] PubMed PMID: 34296623
  • M Stacy J, Khazanie P. Health Insurance and Left Ventricular Assist Device Outcomes: Focus on the Patient Journey, Not the Destination. Circ Heart Fail. 2021 May;14(5):e008558. PubMed PMID: 33993720
  • Bozkurt B, Coats AJ, Tsutsui H, Abdelhamid M, Adamopoulos S, Albert N, Anker SD, Atherton J, Böhm M, Butler J, Drazner MH, Felker GM, Filippatos G, Fonarow GC, Fiuzat M, Gomez-Mesa JE, Heidenreich P, Imamura T, Januzzi J, Jankowska EA, Khazanie P, Kinugawa K, Lam CSP, Matsue Y, Metra M, Ohtani T, Francesco Piepoli M, Ponikowski P, Rosano GMC, Sakata Y, SeferoviC P, Starling RC, Teerlink JR, Vardeny O, Yamamoto K, Yancy C, Zhang J, Zieroth S. Universal Definition and Classification of Heart Failure: A Report of the Heart Failure Society of America, Heart Failure Association of the European Society of Cardiology, Japanese Heart Failure Society and Writing Committee of the Universal Definition of Heart Failure. J Card Fail. 2021 Mar 1. [Epub ahead of print] PubMed PMID: 33663906
  • Bozkurt B, Coats AJS, Tsutsui H, Abdelhamid CM, Adamopoulos S, Albert N, Anker SD, Atherton J, Böhm M, Butler J, Drazner MH, Michael Felker G, Filippatos G, Fiuzat M, Fonarow GC, Gomez-Mesa JE, Heidenreich P, Imamura T, Jankowska EA, Januzzi J, Khazanie P, Kinugawa K, Lam CSP, Matsue Y, Metra M, Ohtani T, Francesco Piepoli M, Ponikowski P, Rosano GMC, Sakata Y, Seferovic P, Starling RC, Teerlink JR, Vardeny O, Yamamoto K, Yancy C, Zhang J, Zieroth S. Universal definition and classification of heart failure: a report of the Heart Failure Society of America, Heart Failure Association of the European Society of Cardiology, Japanese Heart Failure Society and Writing Committee of the Universal Definition of Heart Failure: Endorsed by the Canadian Heart Failure Society, Heart Failure Association of India, Cardiac Society of Australia and New Zealand, and Chinese Heart Failure Association. Eur J Heart Fail. 2021 Mar;23(3):352-380. PubMed PMID: 33605000
  • Kini V, Mosley B, Raghavan S, Khazanie P, Bradley SM, Magid DJ, Ho PM, Masoudi FA. Differences in High- and Low-Value Cardiovascular Testing by Health Insurance Provider. J Am Heart Assoc. 2021 Feb 2;10(3):e018877. PubMed PMID: 33506684
  • Tate CE, Venechuk G, Pierce K, Khazanie P, Ingle MP, Morris MA, Allen LA, Matlock DD. Development of a Decision Aid for Patients and Families Considering Hospice. J Palliat Med. 2021 Apr;24(4):505-513. PubMed PMID: 33439075
  • Flint K, Chaussee EL, Henderson K, Breathett K, Khazanie P, Thompson JS, Mcilvennan CK, Larue SJ, Matlock DD, Allen LA. Social Determinants of Health and Rates of Implantation for Patients Considering Destination Therapy Left Ventricular Assist Device. J Card Fail. 2021 Apr;27(4):497-500. PubMed PMID: 33346077
  • Allen LA, Venechuk G, McIlvennan CK, Page RL 2nd, Knoepke CE, Helmkamp LJ, Khazanie P, Peterson PN, Pierce K, Harger G, Thompson JS, Dow TJ, Richards L, Huang J, Strader JR, Trinkley KE, Kao DP, Magid DJ, Buttrick PM, Matlock DD. An Electronically Delivered Patient-Activation Tool for Intensification of Medications for Chronic Heart Failure With Reduced Ejection Fraction: The EPIC-HF Trial. Circulation. 2021 Feb 2;143(5):427-437. PubMed PMID: 33201741
  • Khazanie P, Allen LA. Systematizing Heart Failure Population Health. Heart Fail Clin. 2020 Oct;16(4):457-466. PubMed PMID: 32888640
  • Venechuk GE, Khazanie P, Page RL 2nd, Knoepke CE, Helmkamp LJ, Peterson PN, Pierce K, Thompson JS, Huang J, Strader JR, Dow TJ, Richards L, Trinkley KE, Kao DP, McIlvennan CK, Magid DJ, Buttrick PM, Matlock DD, Allen LA. An Electronically delivered, Patient-activation tool for Intensification of medications for Chronic Heart Failure with reduced ejection fraction: Rationale and design of the EPIC-HF trial. Am Heart J. 2020 Nov;229:144-155. PubMed PMID: 32866454
  • Mann S, Tobolowsky F, Purohit S, Henao-Martínez A, Bajrovic V, Ramanan P, Wolfel E, Khazanie P, Barron M, Madinger N, Benamu E. Cryptococcal pericarditis in a heart transplant recipient. Transpl Infect Dis. 2020 Dec;22(6):e13366. PubMed PMID: 32533755
  • Monaco J, Khanna A, Khazanie P. Transplant and mechanical circulatory support in patients with adult congenital heart disease. Heart Fail Rev. 2020 Jul;25(4):671-683. PubMed PMID: 32472522
  • Khazanie P, Wynia MK, Dickert NW. Forced Choices: Ethical Challenges in Cardiology During the COVID-19 Pandemic. Circulation. 2020 Jul 21;142(3):194-196. PubMed PMID: 32392096
  • Peters LL, McIlvennan CK, Khazanie P. Evaluation and Management of BK Polyomavirus Viremia in Patients With a Heart Transplant. Prog Transplant. 2019 Dec;29(4):367-370. PubMed PMID: 31711393
  • Khazanie P, Drazner MH. The Blurred Line Between Gaming and Patient Advocacy: Heart Transplant Listing Decisions in the Modern Era. Circulation. 2019 Dec 17;140(25):2048-2050. PubMed PMID: 31529995
  • Khazanie P, Ho PM. Leveraging Value-Based Payment Models to Reduce Sex Differences in Care. Circ Cardiovasc Qual Outcomes. 2019 Aug;12(8):e006038. PubMed PMID: 31416348
  • Khazanie P. REVIVAL of the Sex Disparities Debate: Are Women Denied, Never Referred, or Ineligible for Heart Replacement Therapies?. JACC Heart Fail. 2019 Jul;7(7):612-614. PubMed PMID: 31078479
  • Breathett K, Allen LA, Helmkamp L, Colborn K, Daugherty SL, Blair IV, Jones J, Khazanie P, Mazimba S, McEwen M, Stone J, Calhoun E, Sweitzer NK, Peterson PN. Temporal Trends in Contemporary Use of Ventricular Assist Devices by Race and Ethnicity. Circ Heart Fail. 2018 Aug;11(8):e005008. PubMed PMID: 30021796
  • Allen LA, Khazanie P. Behind the Scenes in "The Real World" of Heart Transplantation: Will You Accept This Rose?. J Am Coll Cardiol. 2018 Apr 24;71(16):1726-1728. PubMed PMID: 29666021
  • Khazanie P, Hellkamp AS, Fonarow GC, Curtis LH, Al-Khatib SM, Hernandez AF. Permanent pacemaker use among patients with heart failure and preserved ejection fraction: Findings from the Acute Decompensated Heart Failure National Registry (ADHERE) National Registry. Am Heart J. 2018 Apr;198:123-128. PubMed PMID: 29653633
  • Khazanie P, Al-Khatib SM, Wang TY, Crowley MJ, Kressin NR, Krumholz HM, Kiefe CI, Wells BL, O'Brien SM, Peterson ED, Sanders GD. Training cardiovascular outcomes researchers: A survey of mentees and mentors to identify critical training gaps and needs. Am Heart J. 2018 Feb;196:170-177. PubMed PMID: 29421010
  • Crowley MJ, Al-Khatib SM, Wang TY, Khazanie P, Kressin NR, Krumholz HM, Kiefe CI, Wells BL, O'Brien SM, Peterson ED, Sanders GD. How well does early-career investigators' cardiovascular outcomes research training align with funded outcomes research?. Am Heart J. 2018 Feb;196:163-169. PubMed PMID: 29421009
  • Breathett K, Allen LA, Helmkamp L, Colborn K, Daugherty SL, Khazanie P, Lindrooth R, Peterson PN. The Affordable Care Act Medicaid Expansion Correlated With Increased Heart Transplant Listings in African-Americans But Not Hispanics or Caucasians. JACC Heart Fail. 2017 Feb;5(2):136-147. PubMed PMID: 28109783
  • Breathett K, Allen LA, Helmkamp L, Colborn K, Daugherty SL, Khazanie P, Lindrooth R, Peterson PN. The Affordable Care Act Medicaid Expansion Correlated With Increased Heart Transplant Listings in African-Americans But Not Hispanics or Caucasians. JACC Heart Fail. 2017 Feb;5(2):136-147. PubMed PMID: 28109783
  • Khazanie P, Krumholz HM, Kiefe CI, Kressin NR, Wells B, Wang TY, Peterson ED. Priorities for Cardiovascular Outcomes Research: A Report of the National Heart, Lung, and Blood Institute's Centers for Cardiovascular Outcomes Research Working Group. Circ Cardiovasc Qual Outcomes. 2017 Jul;10(7). PubMed PMID: 28710296
  • AbouEzzeddine OF, Lala A, Khazanie PP, Shah R, Ho JE, Chen HH, Pang PS, McNulty SE, Anstrom KJ, Hernandez AF, Redfield MM. Evaluation of a provocative dyspnea severity score in acute heart failure. Am Heart J. 2016 Feb;172:34-41. PubMed PMID: 26856213
  • Khazanie P, Liang L, Curtis LH, Butler J, Eapen ZJ, Heidenreich PA, Bhatt DL, Peterson ED, Yancy CW, Fonarow GC, Hernandez AF. Clinical Effectiveness of Hydralazine-Isosorbide Dinitrate Therapy in Patients With Heart Failure and Reduced Ejection Fraction: Findings From the Get With The Guidelines-Heart Failure Registry. Circ Heart Fail. 2016 Feb;9(2):e002444. PubMed PMID: 26867758
  • Khazanie P, Hammill BG, Patel CB, Kiernan MS, Cooper LB, Arnold SV, Fendler TJ, Spertus JA, Curtis LH, Hernandez AF. Use of Heart Failure Medical Therapies Among Patients With Left Ventricular Assist Devices: Insights From INTERMACS. J Card Fail. 2016 Sep;22(9):672-9. PubMed PMID: 26892975
  • Khazanie P, Greiner MA, Al-Khatib SM, Piccini JP, Turakhia MP, Varosy PD, Masoudi FA, Curtis LH, Hernandez AF. Comparative Effectiveness of Cardiac Resynchronization Therapy Among Patients With Heart Failure and Atrial Fibrillation: Findings From the National Cardiovascular Data Registry's Implantable Cardioverter-Defibrillator Registry. Circ Heart Fail. 2016 Jun;9(6). PubMed PMID: 27296396
  • Khazanie P, Allen LA. Meta-Analysis of Medication Adherence Interventions Among Heart Failure Patients: The Lumpers Make Their Case. J Am Heart Assoc. 2016 Jun 17;5(6). PubMed PMID: 27317351
  • Patel PA, Liang L, Khazanie P, Hammill BG, Fonarow GC, Yancy CW, Bhatt DL, Curtis LH, Hernandez AF. Antihyperglycemic Medication Use Among Medicare Beneficiaries With Heart Failure, Diabetes Mellitus, and Chronic Kidney Disease. Circ Heart Fail. 2016 Jul;9(7). PubMed PMID: 27413035
  • Khazanie P, Heizer GM, Hasselblad V, Armstrong PW, Califf RM, Ezekowitz J, Dickstein K, Levy WC, McMurray JJ, Metra M, Tang WH, Teerlink JR, Voors AA, O'Connor CM, Hernandez AF, Starling R. Predictors of clinical outcomes in acute decompensated heart failure: Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure outcome models. Am Heart J. 2015 Aug;170(2):290-7. PubMed PMID: 26299226
  • Khazanie P, Hellkamp AS, Fonarow GC, Bhatt DL, Masoudi FA, Anstrom KJ, Heidenreich PA, Yancy CW, Curtis LH, Hernandez AF, Peterson ED, Al-Khatib SM. Association Between Comorbidities and Outcomes in Heart Failure Patients With and Without an Implantable Cardioverter-Defibrillator for Primary Prevention. J Am Heart Assoc. 2015 Aug 6;4(8):e002061. PubMed PMID: 26251283
  • Lala A, McNulty SE, Mentz RJ, Dunlay SM, Vader JM, AbouEzzeddine OF, DeVore AD, Khazanie P, Redfield MM, Goldsmith SR, Bart BA, Anstrom KJ, Felker GM, Hernandez AF, Stevenson LW. Relief and Recurrence of Congestion During and After Hospitalization for Acute Heart Failure: Insights From Diuretic Optimization Strategy Evaluation in Acute Decompensated Heart Failure (DOSE-AHF) and Cardiorenal Rescue Study in Acute Decompensated Heart Failure (CARESS-HF). Circ Heart Fail. 2015 Jul;8(4):741-8. PubMed PMID: 26041600
  • Zakeri R, Levine JA, Koepp GA, Borlaug BA, Chirinos JA, LeWinter M, VanBuren P, Dávila-Román VG, de Las Fuentes L, Khazanie P, Hernandez A, Anstrom K, Redfield MM. Nitrate's effect on activity tolerance in heart failure with preserved ejection fraction trial: rationale and design. Circ Heart Fail. 2015 Jan;8(1):221-8. PubMed PMID: 25605640
  • Mentz RJ, Greiner MA, DeVore AD, Dunlay SM, Choudhary G, Ahmad T, Khazanie P, Randolph TC, Griswold ME, Eapen ZJ, O'Brien EC, Thomas KL, Curtis LH, Hernandez AF. Ventricular conduction and long-term heart failure outcomes and mortality in African Americans: insights from the Jackson Heart Study. Circ Heart Fail. 2015 Mar;8(2):243-51. PubMed PMID: 25550439
  • Mentz RJ, Stevens SR, DeVore AD, Lala A, Vader JM, AbouEzzeddine OF, Khazanie P, Redfield MM, Stevenson LW, O'Connor CM, Goldsmith SR, Bart BA, Anstrom KJ, Hernandez AF, Braunwald E, Felker GM. Decongestion strategies and renin-angiotensin-aldosterone system activation in acute heart failure. JACC Heart Fail. 2015 Feb;3(2):97-107. PubMed PMID: 25543972
  • Bloomfield GS, Khazanie P, Morris A, Rabadán-Diehl C, Benjamin LA, Murdoch D, Radcliff VS, Velazquez EJ, Hicks C. HIV and noncommunicable cardiovascular and pulmonary diseases in low- and middle-income countries in the ART era: what we know and best directions for future research. J Acquir Immune Defic Syndr. 2014 Sep 1;67 Suppl 1:S40-53. PubMed PMID: 25117960
  • Khazanie P, Hammill BG, Qualls LG, Fonarow GC, Hammill SC, Heidenreich PA, Al-Khatib SM, Piccini JP, Masoudi FA, Peterson PN, Curtis JP, Hernandez AF, Curtis LH. Clinical effectiveness of cardiac resynchronization therapy versus medical therapy alone among patients with heart failure: analysis of the ICD Registry and ADHERE. Circ Heart Fail. 2014 Nov;7(6):926-34. PubMed PMID: 25227768
  • Khazanie P, Liang L, Qualls LG, Curtis LH, Fonarow GC, Hammill BG, Hammill SC, Heidenreich PA, Masoudi FA, Hernandez AF, Piccini JP. Outcomes of medicare beneficiaries with heart failure and atrial fibrillation. JACC Heart Fail. 2014 Feb;2(1):41-8. PubMed PMID: 24622118
  • Khazanie P, Hammill BG, Patel CB, Eapen ZJ, Peterson ED, Rogers JG, Milano CA, Curtis LH, Hernandez AF. Trends in the use and outcomes of ventricular assist devices among medicare beneficiaries, 2006 through 2011. J Am Coll Cardiol. 2014 Apr 15;63(14):1395-404. PubMed PMID: 24486278
  • Khazanie P, Newby LK. ACP Journal Club. Review: in patients with heart failure, ß-blockers reduce mortality but do not differ from each other. Ann Intern Med. 2013 May 21;158(10):JC2-3. PubMed PMID: 23689781
  • Corotto PS, McCarey MM, Adams S, Khazanie P, Whellan DJ. Heart failure patient adherence: epidemiology, cause, and treatment. Heart Fail Clin. 2013 Jan;9(1):49-58. PubMed PMID: 23168317
  • Khazanie P, Granger CB. ACP Journal Club. A 10-year exercise program improved oxygen consumption and quality of life in stable chronic heart failure. Ann Intern Med. 2013 Feb 19;158(4):JC6. PubMed PMID: 23420254
  • Haddad F, Khazanie P, Deuse T, Weisshaar D, Zhou J, Nam CW, Vu TA, Gomari FA, Skhiri M, Simos A, Schnittger I, Vrotvec B, Hunt SA, Fearon WF. Clinical and functional correlates of early microvascular dysfunction after heart transplantation. Circ Heart Fail. 2012 Nov;5(6):759-68. PubMed PMID: 22933526
  • Khazanie P, Rogers JG. Patient selection for left ventricular assist devices. Congest Heart Fail. 2011 Sep-Oct;17(5):227-34. PubMed PMID: 21906247
  • Haddad F, Deuse T, Pham M, Khazanie P, Rosso F, Luikart H, Valantine H, Leon S, Vu TA, Hunt SA, Oyer P, Montoya JG. Changing trends in infectious disease in heart transplantation. J Heart Lung Transplant. 2010 Mar;29(3):306-15. PubMed PMID: 19853478
  • Gupta N, Arthos J, Khazanie P, Steenbeke TD, Censoplano NM, Chung EA, Cruz CC, Chaikin MA, Daucher M, Kottilil S, Mavilio D, Schuck P, Sun PD, Rabin RL, Radaev S, Van Ryk D, Cicala C, Fauci AS. Targeted lysis of HIV-infected cells by natural killer cells armed and triggered by a recombinant immunoglobulin fusion protein: implications for immunotherapy. Virology. 2005 Feb 20;332(2):491-7. PubMed PMID: 15680414
  • Lee TK, Allison RR, O'Brien KF, Khazanie PG, Johnke RM, Brown R, Bloch RM, Tate ML, Dobbs LJ, Kragel PJ. Ginseng reduces the micronuclei yield in lymphocytes after irradiation. Mutat Res. 2004 Jan 10;557(1):75-84. PubMed PMID: 14706520
  • Arthos J, Cicala C, Steenbeke TD, Chun TW, Dela Cruz C, Hanback DB, Khazanie P, Nam D, Schuck P, Selig SM, Van Ryk D, Chaikin MA, Fauci AS. Biochemical and biological characterization of a dodecameric CD4-Ig fusion protein: implications for therapeutic and vaccine strategies. J Biol Chem. 2002 Mar 29;277(13):11456-64. PubMed PMID: 11805109
  • Cicala C, Arthos J, Selig SM, Dennis G Jr, Hosack DA, Van Ryk D, Spangler ML, Steenbeke TD, Khazanie P, Gupta N, Yang J, Daucher M, Lempicki RA, Fauci AS. HIV envelope induces a cascade of cell signals in non-proliferating target cells that favor virus replication. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9380-5. PubMed PMID: 12089333
  • Arthos J, Cicala C, Selig SM, White AA, Ravindranath HM, Van Ryk D, Steenbeke TD, Machado E, Khazanie P, Hanback MS, Hanback DB, Rabin RL, Fauci AS. The role of the CD4 receptor versus HIV coreceptors in envelope-mediated apoptosis in peripheral blood mononuclear cells. Virology. 2002 Jan 5;292(1):98-106. PubMed PMID: 11878912
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Practice Locations

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

UCHealth Heart & Vascular Center - Anschutz
12505 E. 16th Ave
Anschutz Inpatient Pavilion 2, 3rd floor
Aurora, CO 80045
720-848-5300

UCHealth Heart Failure Program - Anschutz
12505 E. 16th Ave
Anschutz Inpatient Pavilion 2, 3rd floor
Aurora, CO 80045
720-848-5300

Hospital Affiliation
  • University of Colorado Hospital

Specialty Information

Specialties
  • Cardiology, Board Certification
  • Internal Medicine, Board Certification (2009)
  • Advanced Heart Failure and Transplant Cardiology
Conditions & Treatments
  • Heart and Circulation - Cardiomyopathy
  • Heart and Circulation
  • Heart and Circulation - Heart Failure
  • Surgery - Heart Transplant Surgery
  • Surgery
Clinical Interests
Cardiology, Heart Failure, Cardiomyopathies (including cardiac sarcoidosis and genetic/inherited cardiomyopathies), Hypertrophic Cardiomyopathy, Pregnancy and heart disease (including Peripartum Cardiomyopathy), Heart Transplantation, Mechanical Circulatory Support / Ventricular Assist Devices

General Information

Medical Schools:
  • MD, Duke University School of Medicine (2006)
Graduate Schools:
  • MPH, University of North Carolina at Chapel Hill (2006)
Undergraduate Schools:
  • BA, Duke University (NC) (2000)
Internships:
  • Stanford Hospital and Clinics Program (2007)
Residency Programs:
  • Stanford Hospital and Clinics Program, Chief Resident, Internal Medicine (2010)
Fellowships:
  • Duke University Hospital Program, Cardiology (2014)
  • Duke University Hospital Program, Advanced Heart Failure and Transplant Cardiology (2015)
Department: Medicine-Cardiology
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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