Cullen Dutmer, MD
Assistant Professor, Pediatrics-Allergy/Immunology

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Medical School:
  • MD, Rush Medical College of Rush University Medical Center (2010)
Undergraduate School:
  • BS, University of Missouri (MO) (2005)
Internship:
  • Johns Hopkins University School of Medicine Program (2011)
Residency:
  • Johns Hopkins University School of Medicine Program, Pediatrics (2013)
Fellowships:
  • National Jewish Medical and Research Center, Allergy and Immunology (2015)
Languages: English
Department: Pediatrics-Allergy/Immunology

Professional Titles

  • Assistant Professor
  • Associate Program Director, Allergy & Immunology Fellowship
  • Co-Director, Severe Combined Immunodeficiency (SCID) Newborn Screening Program in Colorado and Wyoming
  • Medical Director, Clinical Immunology

Recognition & Awards

  • Outstanding Teacher of the Year, Allergy & Immunology Fellowship Program - Children's Hospital Colorado (2021)
  • Outstanding Teacher of the Year, Allergy & Immunology Fellowship Program - Children's Hospital Colorado (2020)
  • Outstanding Teacher of the Year, Allergy & Immunology Fellowship Program - Children's Hospital Colorado (2019)
  • Outstanding Teacher of the Year, Allergy & Immunology Fellowship Program - Children's Hospital Colorado (2018)

Research Interests

I have two primary areas of research: 1. I am a principal investigator and co-investigator on studies aimed at discovering novel inborn errors of immunity and describing unexpected presentations and/or complications of known primary immunodeficiency diseases. 2. I am a co-investigator on projects aimed at studying the effects of environmental exposures on asthma severity and exacerbations in urban children.

Teaching

  • Lecturer (2015)
    School of Medicine, Pediatrics
    Primary Immunodeficiency Diseases
  • Co-Director (2019)
    School of Medicine, Pediatrics
    Advanced Science Course - Immunology & Immunotherapy
  • Associate Program Director (2019)
    School of Medicine, Pediatrics
    Allergy & Immunology Fellowship Program

Publications

  • Knight V, Heimall JR, Wright N, Dutmer CM, Boyce TG, Torgerson TR, Abraham RS. Follow-Up for an Abnormal Newborn Screen for Severe Combined Immunodeficiencies (NBS SCID): A Clinical Immunology Society (CIS) Survey of Current Practices. Int J Neonatal Screen. 2020 Jun 30;6(3). PubMed PMID: 33239578
  • Dyment DA, O'Donnell-Luria A, Agrawal PB, Coban Akdemir Z, Aleck KA, Antaki D, Al Sharhan H, Au PB, Aydin H, Beggs AH, Bilguvar K, Boerwinkle E, Brand H, Brownstein CA, Buyske S, Chodirker B, Choi J, Chudley AE, Clericuzio CL, Cox GF, Curry C, de Boer E, de Vries BBA, Dunn K, Dutmer CM, England EM, Fahrner JA, Geckinli BB, Genetti CA, Gezdirici A, Gibson WT, Gleeson JG, Greenberg CR, Hall A, Hamosh A, Hartley T, Jhangiani SN, Karaca E, Kernohan K, Lauzon JL, Lewis MES, Lowry RB, López-Giráldez F, Matise TC, McEvoy-Venneri J, McInnes B, Mhanni A, Garcia Minaur S, Moilanen J, Nguyen A, Nowaczyk MJM, Posey JE, Õunap K, Pehlivan D, Pajusalu S, Penney LS, Poterba T, Prontera P, Doriqui MJR, Sawyer SL, Sobreira N, Stanley V, Torun D, Wargowski D, Witmer PD, Wong I, Xing J, Zaki MS, Zhang Y, Boycott KM, Bamshad MJ, Nickerson DA, Blue EE, Innes AM. Alternative genomic diagnoses for individuals with a clinical diagnosis of Dubowitz syndrome. Am J Med Genet A. 2020 Oct 24. [Epub ahead of print] PubMed PMID: 33098347
  • Feldman AG, Parsons JA, Dutmer CM, Veerapandiyan A, Hafberg E, Maloney N, Mack CL. Subacute Liver Failure Following Gene Replacement Therapy for Spinal Muscular Atrophy Type 1. J Pediatr. 2020 Oct;225:252-258.e1. PubMed PMID: 32473148
  • Searing DA, Dutmer CM, Fleischer DM, Shaker MS, Oppenheimer J, Grayson MH, Stukus D, Hartog N, Hsieh EWY, Rider NL, Vander Leek TK, Kim H, Chan ES, Mack D, Ellis AK, Abrams EM, Bansal P, Lang DM, Lieberman J, Golden DB, Wallace D, Portnoy J, Mosnaim G, Greenhawt M. A Phased Approach to Resuming Suspended Allergy/Immunology Clinical Services. J Allergy Clin Immunol Pract. 2020 Jul - Aug;8(7):2125-2134. PubMed PMID: 32450236
  • Shaker MS, Oppenheimer J, Grayson M, Stukus D, Hartog N, Hsieh EWY, Rider N, Dutmer CM, Vander Leek TK, Kim H, Chan ES, Mack D, Ellis AK, Lang D, Lieberman J, Fleischer D, Golden DBK, Wallace D, Portnoy J, Mosnaim G, Greenhawt M. Reply to "Subcutaneous terbutaline as an alternative to aerosolized albuterol". J Allergy Clin Immunol Pract. 2020 Jul - Aug;8(7):2450-2452. PubMed PMID: 32340824
  • Dutmer CM, Romberg N. Immunodeficiency Masqueraders. J Allergy Clin Immunol Pract. 2020 Apr;8(4):1468-1469. PubMed PMID: 32276694
  • Shaker MS, Oppenheimer J, Grayson M, Stukus D, Hartog N, Hsieh EWY, Rider N, Dutmer CM, Vander Leek TK, Kim H, Chan ES, Mack D, Ellis AK, Lang D, Lieberman J, Fleischer D, Golden DBK, Wallace D, Portnoy J, Mosnaim G, Greenhawt M. COVID-19: Pandemic Contingency Planning for the Allergy and Immunology Clinic. J Allergy Clin Immunol Pract. 2020 May;8(5):1477-1488.e5. PubMed PMID: 32224232
  • Dutmer CM. Newborn Screening for Severe Combined Immunodeficiency. LabQ Case Studies – American Society for Clinical Pathology. 2020 Feb; https://www.ascp.org/labq.
  • Newman E, Dutmer CM. Atypical Presentation of C8 Alpha Deficiency In A Congolese Boy. J Clin Immunol (2020) 40 (Suppl 1):S17.
  • Ngo S, Nakano T, Dutmer CM. Refractory Autoimmune Hemolytic Anemia Successfully Treated with Daratumumab in a Patient with MHC Class II Deficiency. J Clin Immunol (2020) 40 (Suppl 1):S19.
  • Dutmer CM, Sarin T, Wang C, Hsieh E. Phosphatase and tensin homolog (PTEN) hamartoma tumor syndrome identified by newborn T cell receptor excision circle screening for severe combined immunodeficiency. J Clin Immunol (2020) 40 (Suppl 1):S94.
  • Lin T, Eissa H, Dutmer CM. Successful Allogeneic Hematopoietic Stem Cell Transplantation for Management of Multiple B-Cell Malignancies in a Patient with Primary Intestinal Lymphangiectasia. J Clin Immunol (2020) 40 (Suppl 1):S105.
  • Khan EK, Dutmer CM, Galambos C, Hsieh E, Soep JB, Stillwell PC. Whole Exome Sequencing SAVIes the Day! A Rare Case of STING-Associated Vasculopathy with Onset in Infancy (SAVI) Presenting as Interstitial Lung Disease in a School-Aged Child. American Thoracic Society Annual Meeting: August 5, 2020.
  • Hinds D, Weinman J, Galambos C, Lai J, Dutmer CM, Cordell J, Hoch H. The Alphabet Soup of Bronchiectasis: EVALI Meets EGPA. American Thoracic Society Annual Meeting: August 5, 2020.
  • Ngo S, Dutmer CM. From Novel Discovery to Management Dilemma. Clinical Immunology Society. School in Primary Immunodeficiency Diseases: October 2, 2020.
  • Garcia-Perez JE, Baxter RM, Kong DS, Tobin R, McCarter M, Routes JM, Verbsky J, Jordan MB, Dutmer CM, Hsieh EWY. CTLA4 Message Reflects Pathway Disruption in Monogenic Disorders and Under Therapeutic Blockade. Front Immunol. 2019;10:998. PubMed PMID: 31156616
  • Fernandez IZ, Baxter RM, Garcia-Perez JE, Vendrame E, Ranganath T, Kong DS, Lundquist K, Nguyen T, Ogolla S, Black J, Galambos C, Gumbart JC, Dawany N, Kelsen JR, de Zoeten EF, Quinones R, Eissa H, Verneris MR, Sullivan KE, Rochford R, Blish CA, Kedl RM, Dutmer CM, Hsieh EWY. A novel human IL2RB mutation results in T and NK cell-driven immune dysregulation. J Exp Med. 2019 Jun 3;216(6):1255-1267. PubMed PMID: 31040184
  • Farmer JR, Foldvari Z, Ujhazi B, De Ravin SS, Chen K, Bleesing JJH, Schuetz C, Al-Herz W, Abraham RS, Joshi AY, Costa-Carvalho BT, Buchbinder D, Booth C, Reiff A, Ferguson PJ, Aghamohammadi A, Abolhassani H, Puck JM, Adeli M, Cancrini C, Palma P, Bertaina A, Locatelli F, Di Matteo G, Geha RS, Kanariou MG, Lycopoulou L, Tzanoudaki M, Sleasman JW, Parikh S, Pinero G, Fischer BM, Dbaibo G, Unal E, Patiroglu T, Karakukcu M, Al-Saad KK, Dilley MA, Pai SY, Dutmer CM, Gelfand EW, Geier CB, Eibl MM, Wolf HM, Henderson LA, Hazen MM, Bonfim C, Wolska-Kusnierz B, Butte MJ, Hernandez JD, Nicholas SK, Stepensky P, Chandrakasan S, Miano M, Westermann-Clark E, Goda V, Kriván G, Holland SM, Fadugba O, Henrickson SE, Ozen A, Karakoc-Aydiner E, Baris S, Kiykim A, Bredius R, Hoeger B, Boztug K, Pashchenko O, Neven B, Moshous D, Villartay JP, Bousfiha AA, Hill HR, Notarangelo LD, Walter JE. Outcomes and Treatment Strategies for Autoimmunity and Hyperinflammation in Patients with RAG Deficiency. J Allergy Clin Immunol Pract. 2019 Jul - Aug;7(6):1970-1985.e4. PubMed PMID: 30877075
  • Dutmer CM, Schiltz AM, Freeman KL, Christie MJ, Cerna JA, Cho SH, Chartier RT, Thornburg JW, Hamlington KL, Crooks JL, Fingerlin TE, Schwartz DA, Liu AH. Observed Home Dampness and Mold Are Associated with Sustained Spikes in Personal Exposure to Particulate Matter Less than 10 µm in Diameter in Exacerbation-Prone Children with Asthma. Ann Am Thorac Soc. 2018 Apr;15(Supplement_2):S131-S132. PubMed PMID: 29676636
  • Dutmer CM, Kim H, Searing DA, Zoratti EM, Liu AH. Asthma in inner city children: recent insights: United States. Curr Opin Allergy Clin Immunol. 2018 Apr;18(2):139-147. PubMed PMID: 29406360
  • Anderson WC 3rd, Apter AJ, Dutmer CM, Searing DA, Szefler SJ. Advances in asthma in 2016: Designing individualized approaches to management. J Allergy Clin Immunol. 2017 Sep;140(3):671-680. PubMed PMID: 28709967
  • Liu AH, Anderson WC 3rd, Dutmer CM, Searing DA, Szefler SJ. Advances in asthma 2015: Across the lifespan. J Allergy Clin Immunol. 2016 Aug;138(2):397-404. PubMed PMID: 27497278
  • Dutmer CM, Asturias EJ, Smith C, Dishop MK, Schmid DS, Bellini WJ, Tirosh I, Lee YN, Notarangelo LD, Gelfand EW. Late Onset Hypomorphic RAG2 Deficiency Presentation with Fatal Vaccine-Strain VZV Infection. J Clin Immunol. 2015 Oct 29. [Epub ahead of print] PubMed PMID: 26515615
  • Smith C, Dutmer C, Schmid DS, Dishop MK, Bellini WJ, Gelfand EW, Asturias EJ. A Toddler with Rash, Encephalopathy, and Hemolytic Anemia. J Pediatric Infect Dis Soc. 2015 May 28. [Epub ahead of print] PubMed PMID: 26407265
  • Sarin T, Newman EN, Dutmer CM. Diagnostic Approach to Leukocyte Adhesion Deficiency. LabQ Case Studies – American Society for Clinical Pathology. In-press; https://www.ascp.org/labq.
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Professional Memberships

  • American Academy of Allergy, Asthma & Immunology (AAAAI), Member
  • Clinical Immunology Society (CIS), Member
  • American Thoracic Society (ATS), Member
  • Colorado Allergy & Asthma Society (CAAS), Chairman

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation
  • Children's Hospital Colorado

Specialty Information

Specialties
  • Pediatrics, Board Certification (2013)
  • Allergy and Immunology, Board Certification (2015)
Conditions & Treatments
  • Immune System - Immunodeficiency
  • Lungs and Breathing - Asthma
  • Lungs and Breathing
  • Immune System
Clinical Interests
I am a board certified allergist, immunologist, and pediatrician specializing in primary immunodeficiency diseases and asthma.

Care Philosophy
I have dedicated my career to providing optimal clinical care to patients and families struggling with complex health issues. I believe in a care model in which I actively and thoughtfully collaborate with families and their care teams to provide patient-tailored treatment regimens.

Public Speaking
Yes

General Information

Medical Schools:
  • MD, Rush Medical College of Rush University Medical Center (2010)
Undergraduate Schools:
  • BS, University of Missouri (MO) (2005)
Internships:
  • Johns Hopkins University School of Medicine Program (2011)
Residency Programs:
  • Johns Hopkins University School of Medicine Program, Pediatrics (2013)
Fellowships:
  • National Jewish Medical and Research Center, Allergy and Immunology (2015)
Languages: English
Department: Pediatrics-Allergy/Immunology
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