Jordana Hoppe, MD

Research Interests

My research interests are primarily focused on cystic fibrosis. Specifically I am researching the changes that occur in patients with cystic fibrosis who receive oral antibiotics for the treatment of respiratory illnesses.

Publications

• Mayer-Hamblett N, Gifford AH, Kloster M, Russell R, Braun AT, Gibson RL, Hoppe JE, Jain R, Linnemann RW, Liou TG, Lysinger J, Milla C, Riekert KA, Sawicki GS, Young J, Nichols D. Impact of Discontinuing Both Hypertonic Saline and Dornase Alfa after Elexacaftor-Tezacaftor-Ivacaftor in Cystic Fibrosis. Ann Am Thorac Soc. 2024 Nov;21(11):1507-1515. PubMed PMID: 39041864
• Good A, Shannon J, Brinton JT, Hoppe JE. Implementation and outcomes of a quality improvement project to systematically assess the gross motor skills in school-aged children with cystic fibrosis. Pediatr Pulmonol. 2024 Oct;59(10):2597-2605. PubMed PMID: 38780201
• Hoppe JE, Sjoberg J, Hong G, Poch K, Zemanick ET, Thee S, Edmondson C, Patel D, Sathe M, Borowitz D, Putman MS, Lechtzin N, Riekert KA, Basile M, Goss CH, Jarosz ME, Rosenfeld M. Remote endpoints for clinical trials in cystic fibrosis: Report from the U.S. CF foundation remote endpoints task force. J Cyst Fibros. 2024 Jul;23(4):725-733. PubMed PMID: 38429150
• Sanders DB, Bartz TM, Zemanick ET, Hoppe JE, Hinckley Stukovsky KD, Cogen JD, Bendy L, McNamara S, Enright E, Kime NA, Kronmal RA, Edwards TC, Morgan WJ, Rosenfeld M. A Pilot Randomized Clinical Trial of Pediatric Cystic Fibrosis Pulmonary Exacerbations Treatment Strategies. Ann Am Thorac Soc. 2023 Dec;20(12):1769-1776. PubMed PMID: 37683122
• Goralski JL, Hoppe JE, Mall MA, McColley SA, McKone E, Ramsey B, Rayment JH, Robinson P, Stehling F, Taylor-Cousar JL, Tullis E, Ahluwalia N, Chin A, Chu C, Lu M, Niu T, Weinstock T, Ratjen F, Rosenfeld M. Phase 3 Open-Label Clinical Trial of Elexacaftor/Tezacaftor/Ivacaftor in Children Aged 2-5 Years with Cystic Fibrosis and at Least One F508del Allele. Am J Respir Crit Care Med. 2023 Jul 1;208(1):59-67. PubMed PMID: 36921081
• Jordan KD, Zemanick ET, Taylor-Cousar JL, Hoppe JE. Managing cystic fibrosis in children aged 6-11yrs: a critical review of elexacaftor/tezacaftor/ivacaftor combination therapy. Expert Rev Respir Med. 2023 Feb;17(2):97-108. PubMed PMID: 36803356
• Sagel SD, Kupfer O, Wagner BD, Davis SD, Dell SD, Ferkol TW, Hoppe JE, Rosenfeld M, Sullivan KM, Tiddens HAWM, Knowles MR, Leigh MW. Airway Inflammation in Children with Primary Ciliary Dyskinesia. Ann Am Thorac Soc. 2023 Jan;20(1):67-74. PubMed PMID: 35984413
• Sanders DB, Bartz TM, Zemanick ET, Hoppe JE, Hinckley Stukovsky KD, Cogen JD, Bendy L, McNamara S, Enright E, Kime NA, Kronmal RA, Edwards TC, Morgan WJ, Rosenfeld M. A Pilot Randomized Clinical Trial of Pediatric Cystic Fibrosis Pulmonary Exacerbations Treatment Strategies. Ann Am Thorac Soc. 2023 Dec;20(12):1769-1776. PubMed PMID: 37683122
• Goralski JL, Hoppe JE, Mall MA, McColley SA, McKone E, Ramsey B, Rayment JH, Robinson P, Stehling F, Taylor-Cousar JL, Tullis E, Ahluwalia N, Chin A, Chu C, Lu M, Niu T, Weinstock T, Ratjen F, Rosenfeld M. Phase 3 Open-Label Clinical Trial of Elexacaftor/Tezacaftor/Ivacaftor in Children Aged 2-5 Years with Cystic Fibrosis and at Least One F508del Allele. Am J Respir Crit Care Med. 2023 Jul 1;208(1):59-67. PubMed PMID: 36921081
• Jordan KD, Zemanick ET, Taylor-Cousar JL, Hoppe JE. Managing cystic fibrosis in children aged 6-11yrs: a critical review of elexacaftor/tezacaftor/ivacaftor combination therapy. Expert Rev Respir Med. 2023 Feb;17(2):97-108. PubMed PMID: 36803356
• Sagel SD, Kupfer O, Wagner BD, Davis SD, Dell SD, Ferkol TW, Hoppe JE, Rosenfeld M, Sullivan KM, Tiddens HAWM, Knowles MR, Leigh MW. Airway Inflammation in Children with Primary Ciliary Dyskinesia. Ann Am Thorac Soc. 2023 Jan;20(1):67-74. PubMed PMID: 35984413
• Wolfe AG, Gilley SP, Waldrop SW, Olson C, Harding E, Widmer K, Gumer LB, Haemer M, Hoppe JE. Case report: Cystic fibrosis with kwashiorkor: A rare presentation in the era of universal newborn screening. Front Pediatr. 2022;10:1083155. PubMed PMID: 36683818
• Hoppe JE, Zemanick ET, Martiniano SL. Evidence for Early Cystic Fibrosis Transmembrane Conductance Regulator Modulator Treatment for Children with Cystic Fibrosis Keeps Growing. Am J Respir Crit Care Med. 2022 Dec 1;206(11):1308-1310. PubMed PMID: 35947636
• Hoppe JE, Wagner BD, Kirk Harris J, Rowe SM, Heltshe SL, DeBoer EM, Sagel SD. Effects of ivacaftor on systemic inflammation and the plasma proteome in people with CF and G551D. J Cyst Fibros. 2022 Nov;21(6):950-958. PubMed PMID: 35440409
• Wolfe AG, Gilley SP, Waldrop SW, Olson C, Harding E, Widmer K, Gumer LB, Haemer M, Hoppe JE. Case report: Cystic fibrosis with kwashiorkor: A rare presentation in the era of universal newborn screening. Front Pediatr. 2022;10:1083155. PubMed PMID: 36683818
• Sagel SD, Kupfer O, Wagner BD, Davis SD, Dell SD, Ferkol TW, Hoppe JE, Rosenfeld M, Sullivan KM, Tiddens HAWM, Knowles MR, Leigh MW. Airway Inflammation in Children with Primary Ciliary Dyskinesia. Ann Am Thorac Soc. 2022 Aug 19. [Epub ahead of print] PubMed PMID: 35984413
• Hoppe JE, Zemanick ET, Martiniano SL. Evidence for Early Cystic Fibrosis Transmembrane Conductance Regulator Modulator Treatment for Children with Cystic Fibrosis Keeps Growing. Am J Respir Crit Care Med. 2022 Dec 1;206(11):1308-1310. PubMed PMID: 35947636
• Hoppe JE, Wagner BD, Kirk Harris J, Rowe SM, Heltshe SL, DeBoer EM, Sagel SD. Effects of ivacaftor on systemic inflammation and the plasma proteome in people with CF and G551D. J Cyst Fibros. 2022 Nov;21(6):950-958. PubMed PMID: 35440409
• Hoppe JE, Chilvers M, Ratjen F, McNamara JJ, Owen CA, Tian S, Zahigian R, Cornell AG, McColley SA. Long-term safety of lumacaftor-ivacaftor in children aged 2-5 years with cystic fibrosis homozygous for the F508del-CFTR mutation: a multicentre, phase 3, open-label, extension study. Lancet Respir Med. 2021 Sep;9(9):977-988. PubMed PMID: 33965000
• Lenhart-Pendergrass PM, Anthony M, Sariyska S, Andrews A, Scavezze H, Towler E, Martiniano SL, Hoppe JE, Zemanick ET. Detection of bacterial pathogens using home oropharyngeal swab collection in children with cystic fibrosis. Pediatr Pulmonol. 2021 Jul;56(7):2043-2047. PubMed PMID: 33847465
• Hoppe JE, Chilvers M, Ratjen F, McNamara JJ, Owen CA, Tian S, Zahigian R, Cornell AG, McColley SA. Long-term safety of lumacaftor-ivacaftor in children aged 2-5 years with cystic fibrosis homozygous for the F508del-CFTR mutation: a multicentre, phase 3, open-label, extension study. Lancet Respir Med. 2021 Sep;9(9):977-988. PubMed PMID: 33965000
• Lenhart-Pendergrass PM, Anthony M, Sariyska S, Andrews A, Scavezze H, Towler E, Martiniano SL, Hoppe JE, Zemanick ET. Detection of bacterial pathogens using home oropharyngeal swab collection in children with cystic fibrosis. Pediatr Pulmonol. 2021 Jul;56(7):2043-2047. PubMed PMID: 33847465
• Hoppe JE, Hinds DM, Colborg A, Wagner BD, Morgan WJ, Rosenfeld M, Zemanick ET, Sanders DB. Oral antibiotic prescribing patterns for treatment of pulmonary exacerbations in two large pediatric CF centers. Pediatr Pulmonol. 2020 Dec;55(12):3400-3406. PubMed PMID: 32970375
• Hoppe JE, Guimbellot J, Martiniano SL, Toprak D, Davis C, Daines CL, Muhlebach MS, Esther CR Jr, Dellon EP. Highlights from the 2019 North American Cystic Fibrosis Conference. Pediatr Pulmonol. 2020 Sep;55(9):2225-2232. PubMed PMID: 32573948
• Hoppe JE, Hinds DM, Colborg A, Wagner BD, Morgan WJ, Rosenfeld M, Zemanick ET, Sanders DB. Oral antibiotic prescribing patterns for treatment of pulmonary exacerbations in two large pediatric CF centers. Pediatr Pulmonol. 2020 Dec;55(12):3400-3406. PubMed PMID: 32970375
• Hoppe JE, Guimbellot J, Martiniano SL, Toprak D, Davis C, Daines CL, Muhlebach MS, Esther CR Jr, Dellon EP. Highlights from the 2019 North American Cystic Fibrosis Conference. Pediatr Pulmonol. 2020 Sep;55(9):2225-2232. PubMed PMID: 32573948
• Hoppe JE, Sagel SD. Shifting Landscape of Airway Infection in Early Cystic Fibrosis. Am J Respir Crit Care Med. 2019 Sep 1;200(5):528-529. PubMed PMID: 30875233
• Hoppe JE, Wagner BD, Accurso FJ, Zemanick ET, Sagel SD. Characteristics and outcomes of oral antibiotic treated pulmonary exacerbations in children with cystic fibrosis. J Cyst Fibros. 2018 Jun 16. [Epub ahead of print] PubMed PMID: 29921503
• Muller PA, Mueller JL, Mellenthin M, Murthy R, Capps M, Wagner BD, Alsaker M, Deterding R, Sagel SD, Hoppe J. Evaluation of surrogate measures of pulmonary function derived from electrical impedance tomography data in children with cystic fibrosis. Physiol Meas. 2018 Apr 26;39(4):045008. PubMed PMID: 29565263
• Hoppe JE, Wagner BD, Sagel SD, Accurso FJ, Zemanick ET. Pulmonary exacerbations and clinical outcomes in a longitudinal cohort of infants and preschool children with cystic fibrosis. BMC Pulm Med. 2017 Dec 11;17(1):188. PubMed PMID: 29228933
• Hoppe JE, Zemanick ET. Lessons from the lower airway microbiome in early CF. Thorax. 2017 Dec;72(12):1063-1064. PubMed PMID: 28450530
• Hoppe JE, Zemanick ET. Lessons from the Lower Airway Microbiome in Early CF. Editorial for The Lower Airway Microbiota in Early Cystic Fibrosis Lung Disease: A Longitudinal Analysis. Thorax. 2017, April 27.
• Hoppe JE, Harris JK, Zemanick ET. Assessing the Airway Microbiota in Cystic Fibrosis. Clin. Microbiol. Newsl. 2016 Nov;38(22):179-184.
• Hoppe JE and Accurso FJ. Commentary on Groves et al. Long-Term Outcomes of Children with Intermediate Sweat Chloride Values in Infancy. The Year Book of Pediatrics, 2016.
• Hoppe JE, Towler EE, Wagner BD, Accurso FJ, Sagel SD, Zemanick ET. "Sputum induction improves detection of pathogens in children with cystic fibrosis". Pediatr Pulmonol. 2015 Jul;50(7):638-46.
• Hoppe JE, Wagner BD, Accurso FJ, Zemanick ET. "Longitudinal Evaluation of Pulmonary Exacerbations in Infants and Preschool Children with Cystic Fibrosis" Am J Respir Crit Care Med 191:A3340, 2015.
• Hoppe JE, Dishop MK, DeBoer EM. "Out of the Sandbox and into the Lungs: Chasing Pulmonary Eosinophilia". Am J Respir Crit Casre Med, 191:A5924, 2015
• Hoppe JE and Accurso FJ. Commentary on Groves et al. Long-Term Outcomes of Children with Intermediate Sweat Chloride Values in Infancy. Yearbook of Pediatrics.
• Hoppe JE, Wagner BD, Sagel SD, Accurso FJ, Zemanick ET. "Pulmonary Exacerbations and Clinical Outcomes in a Longitudinal Cohort of Infants and Preschool Children with Cystic Fibrosis". BMC Pulmonary Medicine.

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation

• Children's Hospital Colorado

Specialty Information

Specialties

• Pediatric Pulmonology