Robert Fuhlbrigge, MD, PhD
Professor, Pediatrics-Rheumatology

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Medical School:
  • MD, Washington University in St. Louis School of Medicine (1989)
Graduate School :
  • PhD, Washington University In St. Louis (1989)
Undergraduate School:
  • BS, University of Wisconsin System (WI) (1982)
Internship:
  • Washington University/Barnes-Jewish Hospital/St. Louis Children's Hospital (1989)
Residency:
  • Washington University/Barnes-Jewish Hospital/St. Louis Children's Hospital, Pediatrics (1990)
Fellowships:
  • Children's Hospital (Boston) Program, Pediatric Rheumatology (1992)
Languages: English
Department: Pediatrics-Rheumatology

Professional Titles

  • Professor, Pediatrics-Rheumatology
  • Section Head - Pediatric Rheumatology

Recognition & Awards

  • Pediatric Rheumatology Visiting Professor Award, American College of Rheumatology Research and Education Foundation/ Amgen (2017)
    Teaching award in clinical Pediatric Rheumatology
  • Pediatric Rheumatology Lectureship, James and Nancy Cassidy Foundation (2015)
    Excellence in clinical care in Pediatric Rheumatology
  • CARRA Service Award, CHildhood Arthritis and Rheumatology Research Alliance- CARRA (2013)
    Recognition of outstanding service to CARRA
  • Pediatric Rheumatology Visiting Professor Award, American College of Rheumatology Research and Education Foundation/ Amgen (2011)
    Teaching award in clinical Pediatric Rheumatology
  • Diana Ashby Memorial Research Award, Melanoma Research Foundation (2003)
    Excellence in the field of melanoma research
  • New Investigator Award, The Medical Foundation (1999)
    Excellence in the field of biomedical research

Publications

  • Weiss PF, Fuhlbrigge RC, von Scheven E, Lovell DJ, Colbert RA, Brunner HI. Children with enthesitis-related arthritis could benefit from treatments targeted for adults with spondyloarthritis. Arthritis Care Res (Hoboken). 2020 Dec 5. [Epub ahead of print] PubMed PMID: 33278336
  • Rao S, Kwan BM, Curtis DJ, Swanson A, Bakel LA, Bajaj L, Boguniewicz J, Lockwood JM, Ogawa K, Pemberton K, Fuhlbrigge RC, Brumbaugh D, Givens P, Nozik ES, Sills MR. Implementation of a Rapid Evidence Assessment Infrastructure during the Coronavirus Disease 2019 (COVID-19) Pandemic to Develop Policies, Clinical Pathways, Stimulate Academic Research, and Create Educational Opportunities. J Pediatr. 2020 Oct 20. [Epub ahead of print] PubMed PMID: 33091418
  • Dulek DE, Fuhlbrigge RC, Tribble AC, Connelly JA, Loi MM, El Chebib H, Chandrakasan S, Otto WR, Diorio C, Keim G, Walkovich K, Jaggi P, Girotto JE, Yarbrough A, Behrens EM, Cron RQ, Bassiri H. Multidisciplinary Guidance Regarding the Use of Immunomodulatory Therapies for Acute COVID-19 in Pediatric Patients. J Pediatric Infect Dis Soc. 2020 Aug 18. [Epub ahead of print] PubMed PMID: 32808988
  • Brunner HI, Schanberg LE, Kimura Y, Dennos A, Co DO, Colbert RA, Fuhlbrigge RC, Goldmuntz E, Kingsbury DJ, Patty-Resk C, Mintz S, Onel K, Rider LG, Schneider R, Watts A, von Scheven E, Lovell DJ, Beukelman T. New Medications Are Needed for Children With Juvenile Idiopathic Arthritis. Arthritis Rheumatol. 2020 Nov;72(11):1945-1951. PubMed PMID: 32524767
  • Henderson LA, Hoyt KJ, Lee PY, Rao DA, Jonsson AH, Nguyen JP, Rutherford K, Julé AM, Charbonnier LM, Case S, Chang MH, Cohen EM, Dedeoglu F, Fuhlbrigge RC, Halyabar O, Hazen MM, Janssen E, Kim S, Lo J, Lo MS, Meidan E, Son MBF, Sundel RP, Stoll ML, Nusbaum C, Lederer JA, Chatila TA, Nigrovic PA. Th17 reprogramming of T cells in systemic juvenile idiopathic arthritis. JCI Insight. 2020 Mar 26;5(6). PubMed PMID: 32213704
  • Tian T, Lofftus S, Pan Y, Stingley CA, King SL, Zhao J, Pan TY, Lock R, Marglous JW, Liu K, Widlund HR, Fuhlbrigge RC, Cichowski K, Kupper TS. IL1a Antagonizes IL1ß and Promotes Adaptive Immune Rejection of Malignant Tumors. Cancer Immunol Res. 2020 May;8(5):660-671. PubMed PMID: 32161110
  • Li SC, Torok KS, Rabinovich CE, Dedeoglu F, Becker ML, Ferguson PJ, Hong SD, Ibarra MF, Stewart K, Pope E, Higgins GC, Laxer RM, Mason T 2nd, Fuhlbrigge RC, Andrews T. Initial Results from a Pilot Comparative Effectiveness Study of 3 Methotrexate-based Consensus Treatment Plans for Juvenile Localized Scleroderma. J Rheumatol. 2020 Aug 1;47(8):1242-1252. PubMed PMID: 31615917
  • Aires DJ, Yoshida M, Richardson SK, Bai M, Liu L, Moreno R, Lazar AJF, Wick JA, Rich BE, Murphy G, Blumberg RS, Fuhlbrigge RC, Kupper TS. T-cell trafficking plays an essential role in tumor immunity. Lab Invest. 2019 Jan;99(1):85-92. PubMed PMID: 30353131
  • Wu EY, Li SC, Torok KS, Virkud YV, Fuhlbrigge RC, Rabinovich CE. Baseline Description of the Juvenile Localized Scleroderma Subgroup From the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry. ACR Open Rheumatol. 2019 Apr;1(2):119-124. PubMed PMID: 31777788
  • Li SC, Torok KS, Rabinovich CE, Dedeoglu F, Becker ML, Ferguson PJ, Hong SD, Ibarra MF, Stewart K, Pope E, Higgins GC, Laxer RM, Mason T 2nd, Fuhlbrigge RC, Andrews T. Initial Results from a Pilot Comparative Effectiveness Study of Three Methotrexate-Based Consensus Treatment Plans for Juvenile Localized Scleroderma. J Rheumatol. 2019 Oct 15. [Epub ahead of print] PubMed PMID: 31615917
  • Weishaupt C, Steinert M, Brunner G, Schulze HJ, Fuhlbrigge RC, Goerge T, Loser K. Activation of human vascular endothelium in melanoma metastases induces ICAM-1 and E-selectin expression and results in increased infiltration with effector lymphocytes. Exp Dermatol. 2019 Nov;28(11):1258-1269. PubMed PMID: 31444891
  • Li SC, Fuhlbrigge RC, Laxer RM, Pope E, Ibarra MF, Stewart K, Mason T 2nd, Becker ML, Hong S, Dedeoglu F, Torok KS, Rabinovich CE, Ferguson PJ, Punaro M, Feldman BM, Andrews T, Higgins GC. Developing comparative effectiveness studies for a rare, understudied pediatric disease: lessons learned from the CARRA juvenile localized scleroderma consensus treatment plan pilot study. Pediatr Rheumatol Online J. 2019 Jul 15;17(1):43. PubMed PMID: 31307476
  • Aires DJ, Yoshida M, Richardson SK, Bai M, Liu L, Moreno R, Lazar AJF, Wick JA, Rich BE, Murphy G, Blumberg RS, Fuhlbrigge RC, Kupper TS. T-cell trafficking plays an essential role in tumor immunity. Lab Invest. 2019 Jan;99(1):85-92. PubMed PMID: 30353131
  • Ringold S, Nigrovic PA, Feldman BM, Tomlinson GA, von Scheven E, Wallace CA, Huber AM, Schanberg LE, Li SC, Weiss PF, Fuhlbrigge RC, Morgan EM, Kimura Y. The Childhood Arthritis & Rheumatology Research Alliance Consensus Treatment Plans: Towards Comparative Effectiveness in the Pediatric Rheumatic Diseases. Arthritis Rheumatol. 2018 Jan 15. [Epub ahead of print] PubMed PMID: 29333701
  • Ringold S, Nigrovic PA, Feldman BM, Tomlinson GA, von Scheven E, Wallace CA, Huber AM, Schanberg LE, Li SC, Weiss PF, Fuhlbrigge RC, Morgan EM, Kimura Y. The Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans: Toward Comparative Effectiveness in the Pediatric Rheumatic Diseases. Arthritis Rheumatol. 2018 May;70(5):669-678. PubMed PMID: 29333701
  • Park CO, Fu X, Jiang X, Pan Y, Teague JE, Collins N, Tian T, O'Malley JT, Emerson RO, Kim JH, Jung Y, Watanabe R, Fuhlbrigge RC, Carbone FR, Gebhardt T, Clark RA, Lin CP, Kupper TS. Staged development of long-lived T-cell receptor aß T(H)17 resident memory T-cell population to Candida albicans after skin infection. J Allergy Clin Immunol. 2018 Aug;142(2):647-662. PubMed PMID: 29128674
  • Park CO, Fu X, Jiang X, Pan Y, Teague JE, Collins N, Tian T, O'Malley JT, Emerson RO, Kim JH, Jung Y, Watanabe R, Fuhlbrigge RC, Carbone FR, Gebhardt T, Clark RA, Lin CP, Kupper TS. Staged development of long-lived T-cell receptor aß T(H)17 resident memory T-cell population to Candida albicans after skin infection. J Allergy Clin Immunol. 2017 Nov 9. [Epub ahead of print] PubMed PMID: 29128674
  • Tian T, Jin MQ, Dubin K, King SL, Hoetzenecker W, Murphy GF, Chen CA, Kupper TS, Fuhlbrigge RC. IL-1R Type 1-Deficient Mice Demonstrate an Impaired Host Immune Response against Cutaneous Vaccinia Virus Infection. J Immunol. 2017 Jun 1;198(11):4341-4351. PubMed PMID: 28468973
  • Pan Y, Tian T, Park CO, Lofftus SY, Mei S, Liu X, Luo C, O'Malley JT, Gehad A, Teague JE, Divito SJ, Fuhlbrigge R, Puigserver P, Krueger JG, Hotamisligil GS, Clark RA, Kupper TS. Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism. Nature. 2017 Mar 9;543(7644):252-256. PubMed PMID: 28219080
  • Yoon J, Leyva-Castillo JM, Wang G, Galand C, Oyoshi MK, Kumar L, Hoff S, He R, Chervonsky A, Oppenheim JJ, Kuchroo VK, van den Brink MR, Malefyt Rde W, Tessier PA, Fuhlbrigge R, Rosenstiel P, Terhorst C, Murphy G, Geha RS. IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization. J Exp Med. 2016 Sep 19;213(10):2147-66. PubMed PMID: 27551155
  • Batu ED, Kara Eroglu F, Tsoukas P, Hausmann JS, Bilginer Y, Kenna MA, Licameli GR, Fuhlbrigge RC, Özen S, Dedeoglu F. Periodic Fever, Aphthosis, Pharyngitis, and Adenitis Syndrome: Analysis of Patients From Two Geographic Areas. Arthritis Care Res (Hoboken). 2016 Dec;68(12):1859-1865. PubMed PMID: 27059542
  • Henderson LA, Volpi S, Frugoni F, Janssen E, Kim S, Sundel RP, Dedeoglu F, Lo MS, Hazen MM, Beth Son M, Mathieu R, Zurakowski D, Yu N, Lebedeva T, Fuhlbrigge RC, Walter JE, Nee Lee Y, Nigrovic PA, Notarangelo LD. Next-Generation Sequencing Reveals Restriction and Clonotypic Expansion of Treg Cells in Juvenile Idiopathic Arthritis. Arthritis Rheumatol. 2016 Jul;68(7):1758-68. PubMed PMID: 26815131
  • Bohr AH, Fuhlbrigge RC, Pedersen FK, de Ferranti SD, Müller K. Premature subclinical atherosclerosis in children and young adults with juvenile idiopathic arthritis. A review considering preventive measures. Pediatr Rheumatol Online J. 2016 Jan 6;14(1):3. PubMed PMID: 26738563
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Professional Memberships

  • CARRA- Childhood Arthritis and Rheumatology Research Alliance, Vice-President
  • American College of Rheumatology, Member

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation
  • Children's Hospital Colorado

Specialty Information

Specialties
  • Pediatric Rheumatology, Board Certification
  • Pediatrics, Board Certification
Conditions & Treatments
  • Immune System - Autoimmune Disorders
  • Immune System
  • Immune System - Rheumatoid Arthritis
  • Spine - Sacroiliac Joint
  • Bones, Joints and Muscles - Arthritis
  • Bones, Joints and Muscles
  • Child and Teen Health - Pediatric Diseases and Conditions
  • Child and Teen Health
  • Eyes and Vision - Uveitis and Ocular Immunology
  • Eyes and Vision
  • Genetic Conditions and Testing
  • Lungs and Breathing - Interstitial Lung Disease
  • Lungs and Breathing
  • Lungs and Breathing - Granulomatous Lung Disease
Clinical Interests
Pediatric Rheumatology

Care Philosophy
I strive to provide the best care for my patients, taking every aspect of a patient’s body and health into consideration during diagnosis and treatment.

General Information

Medical Schools:
  • MD, Washington University in St. Louis School of Medicine (1989)
Graduate Schools:
  • PhD, Washington University In St. Louis (1989)
Undergraduate Schools:
  • BS, University of Wisconsin System (WI) (1982)
Internships:
  • Washington University/Barnes-Jewish Hospital/St. Louis Children's Hospital (1989)
Residency Programs:
  • Washington University/Barnes-Jewish Hospital/St. Louis Children's Hospital, Pediatrics (1990)
Fellowships:
  • Children's Hospital (Boston) Program, Pediatric Rheumatology (1992)
Languages: English
Department: Pediatrics-Rheumatology
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