Mitchell Cohen, MD
Professor, Surgery-GI, Trauma, and Endocrine Surgery

Publications

  • Hodgman EI, Cripps MW, Mina MJ, Bulger EM, Schreiber MA, Brasel KJ, Cohen MJ, Muskat P, Myers JG, Alarcon LH, Rahbar MH, Holcomb JB, Cotton BA, Fox EE, Del Junco DJ, Wade CE, Phelan HA. External validation of a smartphone app model to predict the need for massive transfusion using five different definitions. J Trauma Acute Care Surg. 2018 Feb;84(2):397-402. PubMed PMID: 29200079
  • Robinson BRH, Cohen MJ, Holcomb JB, Pritts TA, Gomaa D, Fox EE, Branson RD, Callcut RA, Cotton BA, Schreiber MA, Brasel KJ, Pittet JF, Inaba K, Kerby JD, Scalea TM, Wade CE, Bulger EM. Risk Factors for the Development of Acute Respiratory Distress Syndrome Following Hemorrhage. Shock. 2018 Sep;50(3):258-264. PubMed PMID: 29194339
  • Moskowitz EE, Burlew CC, Moore EE, Pieracci FM, Fox CJ, Campion EM, Lawless RA, Cohen MJ. Preperitoneal pelvic packing is effective for hemorrhage control in open pelvic fractures. Am J Surg. 2018 Apr;215(4):675-677. PubMed PMID: 29179908
  • Kunitake RC, Kornblith LZ, Cohen MJ, Callcut RA. Trauma Early Mortality Prediction Tool (TEMPT) for assessing 28-day mortality. Trauma Surg Acute Care Open. 2018;3(1):e000131. PubMed PMID: 29766125
  • Moazed F, Hendrickson C, Nelson M, Conroy A, Cohen MJ, Calfee CS. Platelet aggregation after blunt trauma is associated with the acute respiratory distress syndrome and altered by cigarette smoke exposure. J Trauma Acute Care Surg. 2018 Feb;84(2):365-371. PubMed PMID: 29140951
  • Robles AJ, Kornblith LZ, Hendrickson CM, Howard BM, Conroy AS, Moazed F, Calfee CS, Cohen MJ, Callcut RA. Health care utilization and the cost of posttraumatic acute respiratory distress syndrome care. J Trauma Acute Care Surg. 2018 Jul;85(1):148-154. PubMed PMID: 29958249
  • Woolley T, Thompson P, Kirkman E, Reed R, Ausset S, Beckett A, Bjerkvig C, Cap AP, Coats T, Cohen M, Despasquale M, Dorlac W, Doughty H, Dutton R, Eastridge B, Glassberg E, Hudson A, Jenkins D, Keenan S, Martinaud C, Miles E, Moore E, Nordmann G, Prat N, Rappold J, Reade MC, Rees P, Rickard R, Schreiber M, Shackelford S, Skogran Eliassen H, Smith J, Smith M, Spinella P, Strandenes G, Ward K, Watts S, White N, Williams S. Trauma Hemostasis and Oxygenation Research Network position paper on the role of hypotensive resuscitation as part of remote damage control resuscitation. J Trauma Acute Care Surg. 2018 Jun;84(6S Suppl 1):S3-S13. PubMed PMID: 29799823
  • Wu TB, Wu S, Buoni M, Orfeo T, Brummel-Ziedins K, Cohen M, Petzold L. Computational Model for Hyperfibrinolytic Onset of Acute Traumatic Coagulopathy. Ann Biomed Eng. 2018 Aug;46(8):1173-1182. PubMed PMID: 29675813
  • Burlew CC, Sumislawski JJ, Behnfield CD, McNutt MK, McCarthy J, Sharpe JP, Croce MA, Bala M, Kashuk J, Spalding MC, Beery PR, John S, Hunt DJ, Harmon L, Stein DM, Callcut R, Wybourn C, Sperry J, Anto V, Dunn J, Veith JP, Brown CVR, Celii A, Zander TL, Coimbra R, Berndtson AE, Moss TZ, Malhotra AK, Hazelton JP, Linden K, West M, Alam HB, Williams AM, Kim J, Inaba K, Moulton S, Choi YM, Warren HL, Collier B, Ball CG, Savage S, Hartwell JL, Cullinane DC, Zielinski MD, Ray-Zack MD, Morse BC, Rhee P, Rutherford EJ, Udekwu P, Reynolds C, Toschlog E, Gondek S, Ju T, Haan JM, Lightwine KL, Kulvatunyou N, Coates B, Khouqeer AF, Todd SR, Zarzaur B, Waller CJ, Kallies KJ, Neideen T, Eddine SBZ, Peck KA, Dunne CE, Kramer K, Bokhari F, Dhillon TS, Galante JM, Cohen MJ. TIME TO STROKE: A WESTERN TRAUMA ASSOCIATION MULTI-CENTER STUDY OF BLUNT CEREBROVASCULAR INJURIES. J Trauma Acute Care Surg. 2018 May 25. [Epub ahead of print] PubMed PMID: 29847537
  • Hendrickson CM, Gibb SL, Miyazawa BY, Keating SM, Ross E, Conroy AS, Calfee CS, Pati S, Cohen MJ. Elevated plasma levels of TIMP-3 are associated with a higher risk of acute respiratory distress syndrome and death following severe isolated traumatic brain injury. Trauma Surg Acute Care Open. 2018;3(1):e000171. PubMed PMID: 30023434
  • Kornblith LZ, Robles AJ, Conroy AS, Hendrickson CM, Calfee CS, Fields AT, Callcut RA, Cohen MJ. Perhaps It's Not the Platelet: Ristocetin Uncovers the Potential Role of von Willebrand Factor in Impaired Platelet Aggregation Following Traumatic Brain Injury. J Trauma Acute Care Surg. 2018 Jul 5. [Epub ahead of print] PubMed PMID: 29985231
  • Stettler GR, Sumislawski JJ, Moore EE, Nunns GR, Kornblith LZ, Conroy AS, Callcut RA, Silliman CC, Banerjee A, Cohen MJ, Sauaia A. Citrated Kaolin Thrombelastography (TEG) Thresholds for Goal-Directed Therapy in Injured Patients Receiving Massive Transfusion. J Trauma Acute Care Surg. 2018 Jul 27. [Epub ahead of print] PubMed PMID: 30059456
  • Ariane Christie S, Hubbard AE, Callcut RA, Hameed M, Dissak-Delon FN, Mekolo D, Saidou A, Mefire AC, Nsongoo P, Dicker RA, Cohen MJ, Juillard C. Machine Learning Without Borders? An Adaptable Tool to Optimize Mortality Prediction in Diverse Clinical Settings. J Trauma Acute Care Surg. 2018 Jul 27. [Epub ahead of print] PubMed PMID: 30059457
  • Ariane Christie S, Hubbard AE, Callcut RA, Hameed M, Dissak-Delon FN, Mekolo D, Saidou A, Mefire AC, Nsongoo P, Dicker RA, Cohen MJ, Juillard C. Machine Learning Without Borders? An Adaptable Tool to Optimize Mortality Prediction in Diverse Clinical Settings. J Trauma Acute Care Surg. 2018 Jul 27. [Epub ahead of print] PubMed PMID: 30059457
  • Panzer AR, Lynch SV, Langelier C, Christie JD, McCauley K, Nelson M, Cheung CK, Benowitz NL, Cohen MJ, Calfee CS. Lung Microbiota Is Related to Smoking Status and to Development of Acute Respiratory Distress Syndrome in Critically Ill Trauma Patients. Am J Respir Crit Care Med. 2018 Mar 1;197(5):621-631. PubMed PMID: 29035085
  • Nunns GR, Moore EE, Stettler GR, Moore HB, Ghasabyan A, Cohen M, Huebner BR, Silliman CC, Banerjee A, Sauaia A. Empiric transfusion strategies during life-threatening hemorrhage. Surgery. 2018 Aug;164(2):306-311. PubMed PMID: 29709368
  • Menezes AA, Vilardi RF, Arkin AP, Cohen MJ. Targeted clinical control of trauma patient coagulation through a thrombin dynamics model. Sci Transl Med. 2017 Jan 4;9(371). PubMed PMID: 28053156
  • Davenport RA, Guerreiro M, Frith D, Rourke C, Platton S, Cohen M, Pearse R, Thiemermann C, Brohi K. Activated Protein C Drives the Hyperfibrinolysis of Acute Traumatic Coagulopathy. Anesthesiology. 2017 Jan;126(1):115-127. PubMed PMID: 27841821
  • Kunitake RC, Howard BM, Kornblith LZ, Christie SA, Conroy AS, Cohen MJ, Callcut RA. Individual clotting factor contributions to mortality following trauma. J Trauma Acute Care Surg. 2017 Feb;82(2):302-308. PubMed PMID: 27906868
  • Cannon JW, Khan MA, Raja AS, Cohen MJ, Como JJ, Cotton BA, Dubose JJ, Fox EE, Inaba K, Rodriguez CJ, Holcomb JB, Duchesne JC. Damage control resuscitation in patients with severe traumatic hemorrhage: A practice management guideline from the Eastern Association for the Surgery of Trauma. J Trauma Acute Care Surg. 2017 Mar;82(3):605-617. PubMed PMID: 28225743
  • Rowell SE, Biffl WL, Brasel K, Moore EE, Albrecht RA, DeMoya M, Namias N, Schreiber MA, Cohen MJ, Shatz DV, Karmy-Jones R, Moore FA. Western Trauma Association Critical Decisions in Trauma: Management of adult blunt splenic trauma-2016 updates. J Trauma Acute Care Surg. 2017 Apr;82(4):787-793. PubMed PMID: 27893644
  • Christie SA, Kornblith LZ, Howard BM, Conroy AS, Kunitake RC, Nelson MF, Hendrickson CM, Calfee CS, Callcut RA, Cohen MJ. Characterization of distinct coagulopathic phenotypes in injury: Pathway-specific drivers and implications for individualized treatment. J Trauma Acute Care Surg. 2017 Jun;82(6):1055-1062. PubMed PMID: 28338598
  • Prior SM, Cohen MJ, Conroy AS, Nelson MF, Kornblith LZ, Howard BM, Butenas S. Correlation between factor (F)XIa, FIXa and tissue factor and trauma severity. J Trauma Acute Care Surg. 2017 Jun;82(6):1073-1079. PubMed PMID: 28328676
  • Cohen MJ. Translational approaches to coagulopathy after trauma: Towards targeted treatment. PLoS Med. 2017 Jul;14(7):e1002359. PubMed PMID: 28742833
  • McCully BH, Connelly CR, Fair KA, Holcomb JB, Fox EE, Wade CE, Bulger EM, Schreiber MA. Onset of Coagulation Function Recovery Is Delayed in Severely Injured Trauma Patients with Venous Thromboembolism. J Am Coll Surg. 2017 Jul;225(1):42-51. PubMed PMID: 28315812
  • Ware LB, Zhao Z, Koyama T, Brown RM, Semler MW, Janz DR, May AK, Fremont RD, Matthay MA, Cohen MJ, Calfee CS. Derivation and validation of a two-biomarker panel for diagnosis of ARDS in patients with severe traumatic injuries. Trauma Surg Acute Care Open. 2017;2(1):e000121. PubMed PMID: 29766112
  • Asehnoune K, Balogh Z, Citerio G, Cap A, Billiar T, Stocchetti N, Cohen MJ, Pelosi P, Curry N, Gaarder C, Gruen R, Holcomb J, Hunt BJ, Juffermans NP, Maegele M, Midwinter M, Moore FA, O'Dwyer M, Pittet JF, Schöchl H, Schreiber M, Spinella PC, Stanworth S, Winfield R, Brohi K. The research agenda for trauma critical care. Intensive Care Med. 2017 Sep;43(9):1340-1351. PubMed PMID: 28756471
  • Callcut RA, Moore S, Wakam G, Hubbard AE, Cohen MJ. Finding the signal in the noise: Could social media be utilized for early hospital notification of multiple casualty events?. PLoS One. 2017;12(10):e0186118. PubMed PMID: 28982201
  • Howard BM, Kornblith LZ, Christie SA, Conroy AS, Nelson MF, Campion EM, Callcut RA, Calfee CS, Lamere BJ, Fadrosh DW, Lynch S, Cohen MJ. Characterizing the gut microbiome in trauma: significant changes in microbial diversity occur early after severe injury. Trauma Surg Acute Care Open. 2017;2(1):e000108. PubMed PMID: 29766103
  • Campion EM, Juillard C, Knudson MM, Dicker R, Cohen MJ, Mackersie R, Campbell AR, Callcut RA. Reconsidering the Resources Needed for Multiple Casualty Events: Lessons Learned From the Crash of Asiana Airlines Flight 214. JAMA Surg. 2016 Jun 1;151(6):512-7. PubMed PMID: 26764565
  • Baimukanova G, Miyazawa B, Potter DR, Muench MO, Bruhn R, Gibb SL, Spinella PC, Cap AP, Cohen MJ, Pati S. Platelets regulate vascular endothelial stability: assessing the storage lesion and donor variability of apheresis platelets. Transfusion. 2016 Mar;56 Suppl 1:S65-75. PubMed PMID: 27001364
  • Howard BM, Kornblith LZ, Cheung CK, Kutcher ME, Miyazawa BY, Vilardi RF, Cohen MJ. Inducing Acute Traumatic Coagulopathy In Vitro: The Effects of Activated Protein C on Healthy Human Whole Blood. PLoS One. 2016;11(3):e0150930. PubMed PMID: 27008408
  • Hendrickson CM, Howard BM, Kornblith LZ, Conroy AS, Nelson MF, Zhuo H, Liu KD, Manley GT, Matthay MA, Calfee CS, Cohen MJ. The acute respiratory distress syndrome following isolated severe traumatic brain injury. J Trauma Acute Care Surg. 2016 Jun;80(6):989-97. PubMed PMID: 26881489
  • Rowell SE, Fair KA, Barbosa RR, Watters JM, Bulger EM, Holcomb JB, Cohen MJ, Rahbar MH, Fox EE, Schreiber MA. The Impact of Pre-Hospital Administration of Lactated Ringer's Solution versus Normal Saline in Patients with Traumatic Brain Injury. J Neurotrauma. 2016 Jun 1;33(11):1054-9. PubMed PMID: 26914721
  • Cohen MJ, Christie SA. New understandings of post injury coagulation and resuscitation. Int J Surg. 2016 Sep;33(Pt B):242-245. PubMed PMID: 27212591
  • Tominaga GT, Staudenmayer KL, Shafi S, Schuster KM, Savage SA, Ross S, Muskat P, Mowery NT, Miller P, Inaba K, Cohen MJ, Ciesla D, Brown CV, Agarwal S, Aboutanos MB, Utter GH, Crandall M. The American Association for the Surgery of Trauma grading scale for 16 emergency general surgery conditions: Disease-specific criteria characterizing anatomic severity grading. J Trauma Acute Care Surg. 2016 Sep;81(3):593-602. PubMed PMID: 27257696
  • Deguchi H, Sinha RK, Marchese P, Ruggeri ZM, Zilberman-Rudenko J, McCarty OJT, Cohen MJ, Griffin JH. Prothrombotic skeletal muscle myosin directly enhances prothrombin activation by binding factors Xa and Va. Blood. 2016 Oct 6;128(14):1870-1878. PubMed PMID: 27421960
  • Kornblith LZ, Howard B, Kunitake R, Redick B, Nelson M, Cohen MJ, Callcut R. Obesity and clotting: Body mass index independently contributes to hypercoagulability after injury. J Trauma Acute Care Surg. 2015 Jan;78(1):30-6; discussion 37-8. PubMed PMID: 25539200
  • Holcomb JB, Tilley BC, Baraniuk S, Fox EE, Wade CE, Podbielski JM, del Junco DJ, Brasel KJ, Bulger EM, Callcut RA, Cohen MJ, Cotton BA, Fabian TC, Inaba K, Kerby JD, Muskat P, O'Keeffe T, Rizoli S, Robinson BR, Scalea TM, Schreiber MA, Stein DM, Weinberg JA, Callum JL, Hess JR, Matijevic N, Miller CN, Pittet JF, Hoyt DB, Pearson GD, Leroux B, van Belle G. Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial. JAMA. 2015 Feb 3;313(5):471-82. PubMed PMID: 25647203
  • Díaz I, Hubbard A, Decker A, Cohen M. Variable importance and prediction methods for longitudinal problems with missing variables. PLoS One. 2015;10(3):e0120031. PubMed PMID: 25815719
  • Kutcher ME, Howard BM, Sperry JL, Hubbard AE, Decker AL, Cuschieri J, Minei JP, Moore EE, Brownstein BH, Maier RV, Cohen MJ. Evolving beyond the vicious triad: Differential mediation of traumatic coagulopathy by injury, shock, and resuscitation. J Trauma Acute Care Surg. 2015 Mar;78(3):516-23. PubMed PMID: 25710421
  • Brown JB, Cohen MJ, Minei JP, Maier RV, West MA, Billiar TR, Peitzman AB, Moore EE, Cuschieri J, Sperry JL. Pretrauma center red blood cell transfusion is associated with reduced mortality and coagulopathy in severely injured patients with blunt trauma. Ann Surg. 2015 May;261(5):997-1005. PubMed PMID: 24670858
  • Pommerening MJ, Goodman MD, Holcomb JB, Wade CE, Fox EE, Del Junco DJ, Brasel KJ, Bulger EM, Cohen MJ, Alarcon LH, Schreiber MA, Myers JG, Phelan HA, Muskat P, Rahbar M, Cotton BA. Clinical gestalt and the prediction of massive transfusion after trauma. Injury. 2015 May;46(5):807-13. PubMed PMID: 25682314
  • Cohen MJ. Homeless Patients in the ICU: An Observational Propensity-Matched Cohort Study. Crit Care Med. 2015 Jun;43(6):1339-40. PubMed PMID: 25978163
  • Mann KG, Freeman K. TACTIC: Trans-Agency Consortium for Trauma-Induced Coagulopathy. J Thromb Haemost. 2015 Jun;13 Suppl 1:S63-71. PubMed PMID: 26149052
  • Privette AR, Evans AE, Moyer JC, Nelson MF, Knudson MM, Mackersie RC, Callcut RA, Cohen MJ. Beyond emergency surgery: redefining acute care surgery. J Surg Res. 2015 Jun 1;196(1):166-71. PubMed PMID: 25799525
  • Moore SE, Decker A, Hubbard A, Callcut RA, Fox EE, Del Junco DJ, Holcomb JB, Rahbar MH, Wade CE, Schreiber MA, Alarcon LH, Brasel KJ, Bulger EM, Cotton BA, Muskat P, Myers JG, Phelan HA, Cohen MJ. Statistical Machines for Trauma Hospital Outcomes Research: Application to the PRospective, Observational, Multi-Center Major Trauma Transfusion (PROMMTT) Study. PLoS One. 2015;10(8):e0136438. PubMed PMID: 26296088
  • Hendrickson CM, Dobbins S, Redick BJ, Greenberg MD, Calfee CS, Cohen MJ. Misclassification of acute respiratory distress syndrome after traumatic injury: The cost of less rigorous approaches. J Trauma Acute Care Surg. 2015 Sep;79(3):417-24. PubMed PMID: 26307875
  • Neal MD, Moore HB, Moore EE, Freeman K, Cohen MJ, Sperry JL, Zuckerbraun BS, Park MS. Clinical assessment of trauma-induced coagulopathy and its contribution to postinjury mortality: A TACTIC proposal. J Trauma Acute Care Surg. 2015 Sep;79(3):490-2. PubMed PMID: 26307885
  • Pommerening MJ, Rahbar E, Minei K, Holcomb JB, Wade CE, Schreiber MA, Cohen MJ, Underwood SJ, Nelson M, Cotton BA. Splenectomy is associated with hypercoagulable thrombelastography values and increased risk of thromboembolism. Surgery. 2015 Sep;158(3):618-26. PubMed PMID: 26209572
  • Rahbar E, Cardenas JC, Matijevic N, Del Junco D, Podbielski J, Cohen MJ, Cotton BA, Holcomb JB, Wade CE. Trauma, Time, and Transfusions: A Longitudinal Analysis of Coagulation Markers in Severely Injured Trauma Patients Receiving Modified Whole Blood or Component Blood Products. Shock. 2015 Nov;44(5):417-25. PubMed PMID: 26263433
  • Howard BM, Miyazawa BY, Dong W, Cedron WJ, Vilardi RF, Ruf W, Cohen MJ. The tissue factor pathway mediates both activation of coagulation and coagulopathy after injury. J Trauma Acute Care Surg. 2015 Dec;79(6):1009-13; discussion 1014. PubMed PMID: 26317815
  • Moren AM, Hamptom D, Diggs B, Kiraly L, Fox EE, Holcomb JB, Rahbar MH, Brasel KJ, Cohen MJ, Bulger EM, Schreiber MA. Recursive partitioning identifies greater than 4 U of packed red blood cells per hour as an improved massive transfusion definition. J Trauma Acute Care Surg. 2015 Dec;79(6):920-4. PubMed PMID: 26680135
  • Spitalnik SL, Triulzi D, Devine DV, Dzik WH, Eder AF, Gernsheimer T, Josephson CD, Kor DJ, Luban NL, Roubinian NH, Mondoro T, Welniak LA, Zou S, Glynn S. 2015 proceedings of the National Heart, Lung, and Blood Institute's State of the Science in Transfusion Medicine symposium. Transfusion. 2015 Sep;55(9):2282-90. PubMed PMID: 26260861
  • Kornblith LZ, Kutcher ME, Redick BJ, Calfee CS, Vilardi RF, Cohen MJ. Fibrinogen and platelet contributions to clot formation: implications for trauma resuscitation and thromboprophylaxis. J Trauma Acute Care Surg. 2014 Feb;76(2):255-6; discussion 262-3. PubMed PMID: 24458031
  • Sperry J, Cohen MJ. Acute obstruction. Surg Clin North Am. 2014 Feb;94(1):77-96. PubMed PMID: 24267500
  • Hagemo JS, Stanworth S, Juffermans NP, Brohi K, Cohen M, Johansson PI, Røislien J, Eken T, Næss PA, Gaarder C. Prevalence, predictors and outcome of hypofibrinogenaemia in trauma: a multicentre observational study. Crit Care. 2014 Mar 26;18(2):R52. PubMed PMID: 24666991
  • Holcomb JB, Fox EE, Scalea TM, Napolitano LM, Albarado R, Gill B, Dunkin BJ, Kirkpatrick AW, Cotton BA, Inaba K, DuBose JJ, Cohen AM, Azizzadeh A, Brenner M, Cohen MJ, Wade CE, Lumsden AB, Andrassy R, Rhee PM, Bass BL, Mattox KL, Britt LD, Eastman AB, Hoyt DB, Rasmussen TE. Current opinion on catheter-based hemorrhage control in trauma patients. J Trauma Acute Care Surg. 2014 Mar;76(3):888-93. PubMed PMID: 24553566
  • Shafi S, Aboutanos M, Brown CV, Ciesla D, Cohen MJ, Crandall ML, Inaba K, Miller PR, Mowery NT. Measuring anatomic severity of disease in emergency general surgery. J Trauma Acute Care Surg. 2014 Mar;76(3):884-7. PubMed PMID: 24553565
  • Bulger EM, Maier RV, Sperry J, Joshi M, Henry S, Moore FA, Moldawer LL, Demetriades D, Talving P, Schreiber M, Ham B, Cohen M, Opal S, Segalovich I, Maislin G, Kaempfer R, Shirvan A. A Novel Drug for Treatment of Necrotizing Soft-Tissue Infections: A Randomized Clinical Trial. JAMA Surg. 2014 Jun;149(6):528-36. PubMed PMID: 24740134
  • Peng J, Zeng J, Cai B, Yang H, Cohen MJ, Chen W, Sun MW, Lu CD, Jiang H. Establishment of quantitative severity evaluation model for spinal cord injury by metabolomic fingerprinting. PLoS One. 2014;9(4):e93736. PubMed PMID: 24727691
  • Cohen MJ. Acute traumatic coagulopathy: clinical characterization and mechanistic investigation. Thromb Res. 2014 May;133 Suppl 1:S25-7. PubMed PMID: 24759135
  • Maegele M, Schöchl H, Cohen MJ. An update on the coagulopathy of trauma. Shock. 2014 May;41 Suppl 1:21-5. PubMed PMID: 24192549
  • Jenkins DH, Rappold JF, Badloe JF, Berséus O, Blackbourne L, Brohi KH, Butler FK, Cap AP, Cohen MJ, Davenport R, DePasquale M, Doughty H, Glassberg E, Hervig T, Hooper TJ, Kozar R, Maegele M, Moore EE, Murdock A, Ness PM, Pati S, Rasmussen T, Sailliol A, Schreiber MA, Sunde GA, van de Watering LM, Ward KR, Weiskopf RB, White NJ, Strandenes G, Spinella PC. Trauma hemostasis and oxygenation research position paper on remote damage control resuscitation: definitions, current practice, and knowledge gaps. Shock. 2014 May;41 Suppl 1:3-12. PubMed PMID: 24430539
  • Cai B, Sigrid B, Redick B, Jiang H, Sun MW, Yang H, Lu CD, Cohen MJ, Cryer H, Zeng J. Comprehensive level one trauma center could lower in-hospital mortality of severe trauma in China. Biomed Environ Sci. 2014 Jul;27(7):537-43. PubMed PMID: 25073913
  • Neal MD, Brown JB, Moore EE, Cuschieri J, Maier RV, Minei JP, Billiar TR, Peitzman AB, Cohen MJ, Sperry JL. Prehospital use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with a reduced incidence of trauma-induced coagulopathy. Ann Surg. 2014 Aug;260(2):378-82. PubMed PMID: 24424149
  • Pommerening MJ, Schwartz DA, Cohen MJ, Schreiber MA, del Junco DJ, Camp EA, Wade CE, Holcomb JB, Cotton BA. Hypercoagulability after injury in premenopausal females: a prospective, multicenter study. Surgery. 2014 Aug;156(2):439-47. PubMed PMID: 24953269
  • Matijevic N, Wang YW, Wade CE, Holcomb JB, Cotton BA, Schreiber MA, Muskat P, Fox EE, Del Junco DJ, Cardenas JC, Rahbar MH, Cohen MJ. Cellular microparticle and thrombogram phenotypes in the Prospective Observational Multicenter Major Trauma Transfusion (PROMMTT) study: correlation with coagulopathy. Thromb Res. 2014 Sep;134(3):652-8. PubMed PMID: 25086657
  • Kornblith LZ, Howard BM, Cheung CK, Dayter Y, Pandey S, Busch MP, Pati S, Callcut RA, Vilardi RF, Redick BJ, Nelson MF, Cohen MJ. The whole is greater than the sum of its parts: hemostatic profiles of whole blood variants. J Trauma Acute Care Surg. 2014 Dec;77(6):818-27. PubMed PMID: 25051379
  • Howard BM, Kornblith LZ, Redick BJ, Vilardi RF, Balhotra KS, Crane JM, Forde MR, Nelson MF, Callcut RA, Cohen MJ. The effects of alcohol on coagulation in trauma patients: interpreting thrombelastography with caution. J Trauma Acute Care Surg. 2014 Dec;77(6):865-71; discussion 871-2. PubMed PMID: 25099451
  • Kutcher ME, Kornblith LZ, Vilardi RF, Redick BJ, Nelson MF, Cohen MJ. The natural history and effect of resuscitation ratio on coagulation after trauma: a prospective cohort study. Ann Surg. 2014 Dec;260(6):1103-11. PubMed PMID: 24846092
  • Kornblith LZ, Cohen MJ. Response: the whole is greater than the sum of its parts: hemostatic profiles of whole-blood variants. J Trauma Acute Care Surg. 2014 Dec;77(6):1003-4. PubMed PMID: 25423545
  • Holcomb JB, del Junco DJ, Fox EE, Wade CE, Cohen MJ, Schreiber MA, Alarcon LH, Bai Y, Brasel KJ, Bulger EM, Cotton BA, Matijevic N, Muskat P, Myers JG, Phelan HA, White CE, Zhang J, Rahbar MH. The prospective, observational, multicenter, major trauma transfusion (PROMMTT) study: comparative effectiveness of a time-varying treatment with competing risks. JAMA Surg. 2013 Feb;148(2):127-36. PubMed PMID: 23560283
  • Callcut RA, Cotton BA, Muskat P, Fox EE, Wade CE, Holcomb JB, Schreiber MA, Rahbar MH, Cohen MJ, Knudson MM, Brasel KJ, Bulger EM, Del Junco DJ, Myers JG, Alarcon LH, Robinson BR. Defining when to initiate massive transfusion: a validation study of individual massive transfusion triggers in PROMMTT patients. J Trauma Acute Care Surg. 2013 Jan;74(1):59-65, 67-8; discussion 66-7. PubMed PMID: 23271078
  • Brakenridge SC, Henley SS, Kashner TM, Golden RM, Paik DH, Phelan HA, Cohen MJ, Sperry JL, Moore EE, Minei JP, Maier RV, Cuschieri J. Comparing clinical predictors of deep venous thrombosis versus pulmonary embolus after severe injury: a new paradigm for posttraumatic venous thromboembolism?. J Trauma Acute Care Surg. 2013 May;74(5):1231-7; discussion 1237-8. PubMed PMID: 23609272
  • Brown JB, Cohen MJ, Minei JP, Maier RV, West MA, Billiar TR, Peitzman AB, Moore EE, Cuschieri J, Sperry JL. Goal-directed resuscitation in the prehospital setting: a propensity-adjusted analysis. J Trauma Acute Care Surg. 2013 May;74(5):1207-12; discussion 1212-4. PubMed PMID: 23609269
  • Grossman AD, Cohen MJ, Manley GT, Butte AJ. Altering physiological networks using drugs: steps towards personalized physiology. BMC Med Genomics. 2013;6 Suppl 2:S7. PubMed PMID: 23819503
  • Hagemo JS, Næss PA, Johansson P, Windeløv NA, Cohen MJ, Røislien J, Brohi K, Heier HE, Hestnes M, Gaarder C. Evaluation of TEG(®) and RoTEM(®) inter-changeability in trauma patients. Injury. 2013 May;44(5):600-5. PubMed PMID: 23260867
  • Kutcher ME, Ferguson AR, Cohen MJ. A principal component analysis of coagulation after trauma. J Trauma Acute Care Surg. 2013 May;74(5):1223-9; discussion 1229-30. PubMed PMID: 23609271
  • Lee TH, McCully BH, Underwood SJ, Cotton BA, Cohen MJ, Schreiber MA. Correlation of conventional thrombelastography and rapid thrombelastography in trauma. Am J Surg. 2013 May;205(5):521-7; discussion 527. PubMed PMID: 23523146
  • Kornblith LZ, Kutcher ME, Evans AE, Redick BJ, Privette A, Schecter WP, Cohen MJ. The "found down" patient: a diagnostic dilemma. J Trauma Acute Care Surg. 2013 Jun;74(6):1548-52. PubMed PMID: 23694886
  • Napolitano LM, Cohen MJ, Cotton BA, Schreiber MA, Moore EE. Tranexamic acid in trauma: how should we use it?. J Trauma Acute Care Surg. 2013 Jun;74(6):1575-86. PubMed PMID: 23694890
  • Barbosa RR, Rowell SE, Fox EE, Holcomb JB, Bulger EM, Phelan HA, Alarcon LH, Myers JG, Brasel KJ, Muskat P, del Junco DJ, Cotton BA, Wade CE, Rahbar MH, Cohen MJ, Schreiber MA. Increasing time to operation is associated with decreased survival in patients with a positive FAST examination requiring emergent laparotomy. J Trauma Acute Care Surg. 2013 Jul;75(1 Suppl 1):S48-52. PubMed PMID: 23778511
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  • Napolitano LM, Cohen MJ, Cotton BA, Schreiber MA, Moore EE. Re: Is viscoelastic evidence of hyperfibrinolysis the ideal indicator for tranexamic acid administration in trauma?. J Trauma Acute Care Surg. 2013 Oct;75(4):743-4. PubMed PMID: 24064893
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  • Christie JD, Wurfel MM, Feng R, O'Keefe GE, Bradfield J, Ware LB, Christiani DC, Calfee CS, Cohen MJ, Matthay M, Meyer NJ, Kim C, Li M, Akey J, Barnes KC, Sevransky J, Lanken PN, May AK, Aplenc R, Maloney JP, Hakonarson H. Genome wide association identifies PPFIA1 as a candidate gene for acute lung injury risk following major trauma. PLoS One. 2012;7(1):e28268. PubMed PMID: 22295056
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  • Barbosa RR, Rowell SE, Sambasivan CN, Diggs BS, Spinella PC, Schreiber MA, Holcomb JB, Wade CE, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, De Moya MA, Schreiber MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Kozar R, Gonzalez EA, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Pomper GJ, Marin B. A predictive model for mortality in massively transfused trauma patients. J Trauma. 2011 Aug;71(2 Suppl 3):S370-4. PubMed PMID: 21814106
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  • Holcomb JB, Zarzabal LA, Michalek JE, Kozar RA, Spinella PC, Perkins JG, Matijevic N, Dong JF, Pati S, Wade CE, Holcomb JB, Wade CE, Cotton BA, Kozar RA, Brasel KJ, Vercruysse GA, MacLeod JB, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat PC, Johannigamn JA, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, DeMoya MA, Schreiber MA, Tieu BH, Brundage SI, Napolitano LM, Brunsvold ME, Sihler KC, Beilman GJ, Peitzman AB, Zenati MS, Sperry JL, Alarcon LH, Croce MA, Minei JP, Steward RM, Cohn SM, Michalek JE, Bulger EM, Nunez TC, Ivatury RR, Meredith JW, Miller PR, Pomper GJ, Marin B. Increased platelet:RBC ratios are associated with improved survival after massive transfusion. J Trauma. 2011 Aug;71(2 Suppl 3):S318-28. PubMed PMID: 21814099
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  • Barbosa RR, Rowell SE, Diggs BS, Schreiber MA, Holcomb JB, Wade CE, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, De Moya MA, Schreiber MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Kozar R, Gonzalez EA, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Miller P, Pomper GJ, Marin B. Profoundly abnormal initial physiologic and biochemical data cannot be used to determine futility in massively transfused trauma patients. J Trauma. 2011 Aug;71(2 Suppl 3):S364-9. PubMed PMID: 21814105
  • Rowell SE, Barbosa RR, Allison CE, Van PY, Schreiber MA, Holcomb JB, Wade CE, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, De Moya MA, Schreiber MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Kozar R, Gonzalez EA, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Pomper P, Pomper GJ, Marin B. Gender-based differences in mortality in response to high product ratio massive transfusion. J Trauma. 2011 Aug;71(2 Suppl 3):S375-9. PubMed PMID: 21814107
  • Spoerke N, Michalek J, Schreiber M, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, De Moya MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Miller P, Pomper GJ, Marin B. Crystalloid resuscitation improves survival in trauma patients receiving low ratios of fresh frozen plasma to packed red blood cells. J Trauma. 2011 Aug;71(2 Suppl 3):S380-3. PubMed PMID: 21814108
  • Rowell SE, Barbosa RR, Diggs BS, Schreiber MA, Holcomb JB, Wade CE, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, De Moya MA, Schreiber MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Kozar R, Gonzalez EA, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Miller P, Pomper J, Marin B. Specific abbreviated injury scale values are responsible for the underestimation of mortality in penetrating trauma patients by the injury severity score. J Trauma. 2011 Aug;71(2 Suppl 3):S384-8. PubMed PMID: 21814109
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  • Grossman AD, Cohen MJ, Manley GT, Butte AJ. Infection in the intensive care unit alters physiological networks. BMC Bioinformatics. 2009 Sep 17;10 Suppl 9:S4. PubMed PMID: 19761574
  • Chesebro BB, Rahn P, Carles M, Esmon CT, Xu J, Brohi K, Frith D, Pittet JF, Cohen MJ. Increase in activated protein C mediates acute traumatic coagulopathy in mice. Shock. 2009 Dec;32(6):659-65. PubMed PMID: 19333141
  • Cohen MJ, Bir N, Rahn P, Dotson R, Brohi K, Chesebro BB, Mackersie R, Carles M, Wiener-Kronish J, Pittet JF. Protein C depletion early after trauma increases the risk of ventilator-associated pneumonia. J Trauma. 2009 Dec;67(6):1176-81. PubMed PMID: 20009664
  • Ganter MT, Cohen MJ, Brohi K, Chesebro BB, Staudenmayer KL, Rahn P, Christiaans SC, Bir ND, Pittet JF. Angiopoietin-2, marker and mediator of endothelial activation with prognostic significance early after trauma?. Ann Surg. 2008 Feb;247(2):320-6. PubMed PMID: 18216540
  • Knudson MM, Khaw L, Bullard MK, Dicker R, Cohen MJ, Staudenmayer K, Sadjadi J, Howard S, Gaba D, Krummel T. Trauma training in simulation: translating skills from SIM time to real time. J Trauma. 2008 Feb;64(2):255-63; discussion 263-4. PubMed PMID: 18301184
  • Rosenthal G, Morabito D, Cohen M, Roeytenberg A, Derugin N, Panter SS, Knudson MM, Manley G. Use of hemoglobin-based oxygen-carrying solution-201 to improve resuscitation parameters and prevent secondary brain injury in a swine model of traumatic brain injury and hemorrhage: laboratory investigation. J Neurosurg. 2008 Mar;108(3):575-87. PubMed PMID: 18312106
  • Brohi K, Cohen MJ, Ganter MT, Schultz MJ, Levi M, Mackersie RC, Pittet JF. Acute coagulopathy of trauma: hypoperfusion induces systemic anticoagulation and hyperfibrinolysis. J Trauma. 2008 May;64(5):1211-7; discussion 1217. PubMed PMID: 18469643
  • Ganter MT, Brohi K, Cohen MJ, Shaffer LA, Walsh MC, Stahl GL, Pittet JF. Role of the alternative pathway in the early complement activation following major trauma. Shock. 2007 Jul;28(1):29-34. PubMed PMID: 17510601
  • Cohen MJ, Brohi K, Ganter MT, Manley GT, Mackersie RC, Pittet JF. Early coagulopathy after traumatic brain injury: the role of hypoperfusion and the protein C pathway. J Trauma. 2007 Dec;63(6):1254-61; discussion 1261-2. PubMed PMID: 18212647
  • Brohi K, Cohen MJ, Davenport RA. Acute coagulopathy of trauma: mechanism, identification and effect. Curr Opin Crit Care. 2007 Dec;13(6):680-5. PubMed PMID: 17975390
  • Cohen MJ, Carroll C, He LK, Muthu K, Gamelli RL, Jones SB, Shankar R. Severity of burn injury and sepsis determines the cytokine responses of bone marrow progenitor-derived macrophages. J Trauma. 2007 Apr;62(4):858-67. PubMed PMID: 17426540
  • Brohi K, Cohen MJ, Ganter MT, Matthay MA, Mackersie RC, Pittet JF. Acute traumatic coagulopathy: initiated by hypoperfusion: modulated through the protein C pathway?. Ann Surg. 2007 May;245(5):812-8. PubMed PMID: 17457176
  • Ikossi DG, Knudson MM, Morabito DJ, Cohen MJ, Wan JJ, Khaw L, Stewart CJ, Hemphill C, Manley GT. Continuous muscle tissue oxygenation in critically injured patients: a prospective observational study. J Trauma. 2006 Oct;61(4):780-8; discussion 788-90. PubMed PMID: 17033541
  • Cohen MJ, Schecter WP. Perioperative pain control: a strategy for management. Surg Clin North Am. 2005 Dec;85(6):1243-57, xi. PubMed PMID: 16326205
  • Cohen MJ, Shankar R, Stevenson J, Fernandez R, Gamelli RL, Jones SB. Bone marrow norepinephrine mediates development of functionally different macrophages after thermal injury and sepsis. Ann Surg. 2004 Jul;240(1):132-41. PubMed PMID: 15213629
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General Information

Department: Surgery-GI, Trauma, and Endocrine Surgery
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