Kelly Doran, PhD
Professor, Immunology and Microbiology

Publications

• Spencer BL, Tak U, Mendonça JC, Nagao PE, Niederweis M, Doran KS. A type VII secretion system in Group B Streptococcus mediates cytotoxicity and virulence. PLoS Pathog. 2021 Dec;17(12):e1010121. PubMed PMID: 34871327
• Keogh RA, Spencer BL, Sorensen HM, Zapf RL, Briaud P, Bonsall AE, Doran KS, Carroll RK. Global Annotation, Expression Analysis, and Stability of Candidate sRNAs in Group B Streptococcus. mBio. 2021 Dec 21;12(6):e0280321. PubMed PMID: 34724819
• Villarreal R, Manzer HS, Keestra-Gounder AM, Doran KS. Vimentin Regulates Chemokine Expression and NOD2 Activation in Brain Endothelium during Group B Streptococcal Infection. Infect Immun. 2021 Nov 16;89(12):e0034021. PubMed PMID: 34491787
• Spencer BL, Doran KS, Burcham LR. The Virtual Streptococcal Seminar Series and Trainee Symposium: Adaptations of a Research Community during the COVID-19 Pandemic. J Microbiol Biol Educ. 2021;22(1). PubMed PMID: 33884095
• van Sorge NM, Bonsor DA, Deng L, Lindahl E, Schmitt V, Lyndin M, Schmidt A, Nilsson OR, Brizuela J, Boero E, Sundberg EJ, van Strijp JAG, Doran KS, Singer BB, Lindahl G, McCarthy AJ. Bacterial protein domains with a novel Ig-like fold target human CEACAM receptors. EMBO J. 2021 Apr 1;40(7):e106103. PubMed PMID: 33522633
• Spencer BL, Chatterjee A, Duerkop BA, Baker CJ, Doran KS. Complete Genome Sequence of Neonatal Clinical Group B Streptococcal Isolate CJB111. Microbiol Resour Announc. 2021 Jan 14;10(2). PubMed PMID: 33446593
• de Figueiredo Sanches G, Lannes-Costa PS, Cristoforêto MC, Doran KS, Mattos-Guaraldi AL, Nagao PE. Streptococcus agalactiae strains isolated from cancer patients in Rio de Janeiro, Brazil. Braz J Microbiol. 2021 Mar;52(1):303-310. PubMed PMID: 33398672
• Manzer HS, Nobbs AH, Doran KS. The Multifaceted Nature of Streptococcal Antigen I/II Proteins in Colonization and Disease Pathogenesis. Front Microbiol. 2020;11:602305. PubMed PMID: 33329493
• Burcham LR, Le Breton Y, Radin JN, Spencer BL, Deng L, Hiron A, Ransom MR, Mendonça JDC, Belew AT, El-Sayed NM, McIver KS, Kehl-Fie TE, Doran KS. Identification of Zinc-Dependent Mechanisms Used by Group B Streptococcus To Overcome Calprotectin-Mediated Stress. mBio. 2020 Nov 10;11(6). PubMed PMID: 33173000
• Alhajjar N, Chatterjee A, Spencer BL, Burcham LR, Willett JLE, Dunny GM, Duerkop BA, Doran KS. Genome-Wide Mutagenesis Identifies Factors Involved in Enterococcus faecalis Vaginal Adherence and Persistence. Infect Immun. 2020 Sep 18;88(10). PubMed PMID: 32778611
• Campeau A, Mills RH, Blanchette M, Bajc K, Malfavon M, Munji RN, Deng L, Hancock B, Patras KA, Olson J, Nizet V, Daneman R, Doran K, Gonzalez DJ. Multidimensional Proteome Profiling of Blood-Brain Barrier Perturbation by Group B Streptococcus . mSystems. 2020 Aug 25;5(4). PubMed PMID: 32843537
• Lannes-Costa PS, Baraúna RA, Ramos JN, Veras JFC, Conceição MVR, Vieira VV, de Mattos-Guaraldi AL, Ramos RTJ, Doran KS, Silva A, Nagao PE. Comparative genomic analysis and identification of pathogenicity islands of hypervirulent ST-17 Streptococcus agalactiae Brazilian strain. Infect Genet Evol. 2020 Jun;80:104195. PubMed PMID: 31954181
• Kim BJ, McDonagh MA, Deng L, Gastfriend BD, Schubert-Unkmeir A, Doran KS, Shusta EV. Streptococcus agalactiae disrupts P-glycoprotein function in brain endothelial cells. Fluids Barriers CNS. 2019 Aug 22;16(1):26. PubMed PMID: 31434575
• Deng L, Mu R, Weston TA, Spencer BL, Liles R, Doran KS. Characterization of a two-component system transcriptional regulator LtdR that impacts Group B Streptococcal colonization and disease. Infect Immun. 2018 Apr 23. [Epub ahead of print] PubMed PMID: 29685987
• Vornhagen J, Armistead B, Santana-Ufret V, Gendrin C, Merillat S, Coleman M, Quach P, Boldenow E, Alishetti V, Leonhard-Melief C, Ngo LY, Whidbey C, Doran KS, Curtis C, Waldorf KMA, Nance E, Rajagopal L. Group B streptococcus exploits vaginal epithelial exfoliation for ascending infection. J Clin Invest. 2018 May 1;128(5):1985-1999. PubMed PMID: 29629904
• Gendrin C, Shubin NJ, Boldenow E, Merillat S, Clauson M, Power D, Doran KS, Abrink M, Pejler G, Rajagopal L, Piliponsky AM. Mast cell chymase decreases the severity of group B Streptococcus infections. J Allergy Clin Immunol. 2018 Jul;142(1):120-129.e6. PubMed PMID: 28916188
• Gendrin C, Shubin NJ, Boldenow E, Merillat S, Clauson M, Power D, Doran KS, Abrink M, Pejler G, Rajagopal L, Piliponsky AM. Mast cell chymase decreases the severity of group B Streptococcus infections. J Allergy Clin Immunol. 2017 Sep 12. [Epub ahead of print] PubMed PMID: 28916188
• Lazzarin M, Mu R, Fabbrini M, Ghezzo C, Rinaudo CD, Doran KS, Margarit I. Contribution of pilus type 2b to invasive disease caused by a Streptococcus agalactiae ST-17 strain. BMC Microbiol. 2017 Jul 3;17(1):148. PubMed PMID: 28673237
• Lin AE, Autran CA, Szyszka A, Escajadillo T, Huang M, Godula K, Prudden AR, Boons GJ, Lewis AL, Doran KS, Nizet V, Bode L. Human milk oligosaccharides inhibit growth of group B Streptococcus . J Biol Chem. 2017 Jul 7;292(27):11243-11249. PubMed PMID: 28416607
• Lozano-Pope I, Sharma A, Matthias M, Doran KS, Obonyo M. Effect of myeloid differentiation primary response gene 88 on expression profiles of genes during the development and progression of Helicobacter-induced gastric cancer. BMC Cancer. 2017 Feb 15;17(1):133. PubMed PMID: 28201999
• Spencer BL, Chatterjee A, Duerkop BA, Baker CJ, Doran KS. Genome-Wide Mutagenesis Identifies Factors Involved in Enterococcus The complete genome of neonatal clinical group B streptococcal isolate, CJB111. Microbiology Resource Announcements (MRA) in press
• van Sorge NM, Bonsor, DA, Deng L, Lindahl E, Schmitt V, Lyndin M, Schmidt A, Nilsson OR, Brizuela J, Boero E, Sundberg EJ, van Strijp JAG, Doran KS, Singer BB, Lindahl G, McCarthy AJ. Bacterial protein domains with a novel Ig-like fold target human CEACAM receptors. The EMBO Journal. in press.