Laura Wiley, PhD
Assistant Professor, Medicine-Bioinformatics

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Graduate Schools :
  • MS, Vanderbilt University (2014)
  • PhD, Vanderbilt University (2016)
Undergraduate Schools:
  • BS, University of Denver (CO) (2009)
  • BCh, University of Denver (CO) (2009)
Department: Medicine-Bioinformatics

Research Interests

The Wiley Lab develops methods for using electronic health record data for clinical evidence generation and biomedical research in support of precision medicine. Ongoing projects include building and mining a clinical data repository to inform clinical management of intracranial aneurysms, developing tools to support abstraction of medical charts, and supporting informatics and data science needs of other collaborative projects in genomics and precision medicine.

Teaching

  • Co-Director, Coursera Clinical Data Science Specialization (2021)
    School of Medicine,
    This specialization provides learners with hands on experience in use of electronic health records and informatics tools to perform clinical data science. The series of six courses is designed to augment learner’s existing skills in statistics and programming to provide examples of specific challenges, tools, and appropriate interpretations of clinical data. At the end of the specialization, students will know how to: 1) understand electronic health record data types and structures, 2) deploy basic informatics methodologies on clinical data, 3) provide appropriate clinical and scientific interpretation of applied analyses, and 4) anticipate barriers in implementing informatics tools into complex clinical settings. Students demonstrate mastery of these skills by completing practical application projects using real clinical data. Thanks to our industry partnership with Google Cloud, all students have access to a fully hosted online data science computational environment.

Publications

  • Seligson ND, Warner JL, Dalton WS, Martin D, Miller RS, Patt D, Kehl KL, Palchuk MB, Alterovitz G, Wiley LK, Huang M, Shen F, Wang Y, Nguyen KA, Wong AF, Meric-Bernstam F, Bernstam EV, Chen JL. Recommendations for patient similarity classes: results of the AMIA 2019 workshop on defining patient similarity. J Am Med Inform Assoc. 2020 Nov 1;27(11):1808-1812. PubMed PMID: 32885823
  • Roark CD, Beseler C, Wiley LK, Case D, Folzenlogen Z, Hosokawa P, Seinfeld J. Predictors of 90-Day Readmission Rate After Unruptured Intracranial Aneurysm Repair. World Neurosurg. 2020 Sep;141:e728-e735. PubMed PMID: 32525089
  • Southerland WM, Swamidass SJ, Payne PRO, Wiley L, Williams-DeVane C. The diversity and disparity in biomedical informatics (DDBI) workshop. Pac Symp Biocomput. 2018;23:614-617. PubMed PMID: 29218919
  • Ching T, Himmelstein DS, Beaulieu-Jones BK, Kalinin AA, Do BT, Way GP, Ferrero E, Agapow PM, Zietz M, Hoffman MM, Xie W, Rosen GL, Lengerich BJ, Israeli J, Lanchantin J, Woloszynek S, Carpenter AE, Shrikumar A, Xu J, Cofer EM, Lavender CA, Turaga SC, Alexandari AM, Lu Z, Harris DJ, DeCaprio D, Qi Y, Kundaje A, Peng Y, Wiley LK, Segler MHS, Boca SM, Swamidass SJ, Huang A, Gitter A, Greene CS. Opportunities and obstacles for deep learning in biology and medicine. J R Soc Interface. 2018 Apr;15(141). PubMed PMID: 29618526
  • Southerland WM, Swamidass SJ, Payne PRO, Wiley L, Williams-DeVane C. The diversity and disparity in biomedical informatics (DDBI) workshop. Pac Symp Biocomput. 2018;23:614-617. PubMed PMID: 29218919
  • Mayer D, Russell S, Wilson MP, Kahn MG, Wiley LK. Developing and Deploying a Scalable Computing Platform to Support MOOC Education in Clinical Data Science. AMIA 2021 Informatics Summit. Accepted.
  • Roark C, Wilson MP, Kubes S, Mayer D, Wiley LK. Assessing the Utility and Accuracy of ICD10-CM Nontraumatic Subarachnoid Hemorrhage Codes for Intracranial Aneurysm Research. Learning Health Systems. Accepted.
  • Hicks JK, El Rouby N, Ong HH, Schildcrout JS, Ramsey L, Shi Y, Tang LA, Aquilante CL, Beitelshees AL, Blake KV, Cimino JJ, Davis BH, Empey PE, Kao DP, Lemkin DL, Limdi NA, Lipori GP, Rosenman MB, Skaar TC, Teal E, Tuteja S, Wiley LK, Williams H, Winterstein AG, Van Driest SL, Cavallari LH, Peterson JF. Opportunity for Genotype-Guided Prescribing Among Adult Patients in 11 US-Affiliated Health Systems. Clinical Pharmacology and Therapeutics. Accepted.
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Public Speaking
Yes

General Information

Graduate Schools:
  • MS, Vanderbilt University (2014)
  • PhD, Vanderbilt University (2016)
Undergraduate Schools:
  • BS, University of Denver (CO) (2009)
  • BCh, University of Denver (CO) (2009)
Department: Medicine-Bioinformatics
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