Matthew Wicklund, MD
Professor, Neurology

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Medical School:
  • MD, University of Colorado Denver School of Medicine (1987)
Undergraduate School:
  • BA, University of Colorado - Boulder (CO) (1981)
Internship:
  • Dartmouth-Hitchcock Medical Center Program (1988)
Residency:
  • San Antonio Uniformed Services Health Education Consortium (WHMC) Program, Chief Resident, Neurology (1996)
Fellowships:
  • Ohio State University Hospital Program, Neuromuscular Medicine (2001)
Languages: English
Department: Neurology

Professional Titles

  • Professor of Neurology

Recognition & Awards

  • Best Doctors in America, Best Doctors (2020)
  • Best Doctors in America, Best Doctors (2019)
  • 5280 Top Doctors - Neuromuscular Medicine, 5280 Magazine (2019)
  • Best Doctors in America, Best Doctors (2017)
  • Best Doctors in America, Best Doctors (2016)
  • Best Doctors in America, Best Doctors (2015)

Research Interests

Muscular dystrophies. Genetic muscle diseases. Neuromuscular causes of weakness.

Teaching

  • Professor of Neurology (2017)
    School of Medicine, Neurology

Publications

  • Barohn RJ, Gajewski B, Pasnoor M, Brown A, Herbelin LL, Kimminau KS, Mudaranthakam DP, Jawdat O, Dimachkie MM, Iyadurai S, Stino A, Kissel J, Pascuzzi R, Brannagan T, Wicklund M, Ahmed A, Walk D, Smith G, Quan D, Heitzman D, Tobon A, Ladha S, Wolfe G, Pulley M, Hayat G, Li Y, Thaisetthawatkul P, Lewis R, Biliciler S, Sharma K, Salajegheh K, Trivedi J, Mallonee W, Burns T, Jacoby M, Bril V, Vu T, Ramchandren S, Bazant M, Austin S, Karam C, Hussain Y, Kutz C, Twydell P, Scelsa S, Kushlaf H, Wymer J, Hehir M, Kolb N, Ralph J, Barboi A, Verma N, Ahmed M, Memon A, Saperstein D, Lou JS, Swenson A, Cash T. Patient Assisted Intervention for Neuropathy: Comparison of Treatment in Real Life Situations (PAIN-CONTRoLS): Bayesian Adaptive Comparative Effectiveness Randomized Trial. JAMA Neurol. 2020 Aug 17. [Epub ahead of print] PubMed PMID: 32809014
  • Bockhorst J, Wicklund M. Limb Girdle Muscular Dystrophies. Neurol Clin. 2020 Aug;38(3):493-504. PubMed PMID: 32703463
  • Clemens PR, Niizawa G, Feng J, Florence J, D'Alessandro AS, Morgenroth LP, Gorni K, Guglieri M, Connolly A, Wicklund M, Bertorini T, Mah JK, Thangarajh M, Smith E, Kuntz N, McDonald CM, Henricson EK, Upadhyayula S, Byrne B, Manousakis G, Harper A, Bravver E, Iannaccone S, Spurney C, Cnaan A, Gordish-Dressman H. The CINRG Becker Natural History Study: Baseline characteristics. Muscle Nerve. 2020 Sep;62(3):369-376. PubMed PMID: 32564389
  • Kern V, Wicklund M, Haulman A, McDermott MP, Martens WB, Griggs RC, Kumar A. Ankle bracing practices in ambulatory, corticosteroid-naive boys with Duchenne muscular dystrophy. Muscle Nerve. 2020 Jan;61(1):52-57. PubMed PMID: 31588574
  • Aburahma SK, Wicklund MP, Quan D. Take two: Utility of the repeat skeletal muscle biopsy. Muscle Nerve. 2019 Jul;60(1):41-46. PubMed PMID: 30972775
  • Hunter M, Heatwole C, Wicklund M, Weihl CC, Mozaffar T, Statland JM, Johnson NE. Limb-girdle muscular dystrophy: A perspective from adult patients on what matters most. Muscle Nerve. 2019 Oct;60(4):419-424. PubMed PMID: 31298728
  • Kern V, Wicklund M, Haulman A, McDermott MP, Martens WB, Griggs RC, Kumar A. Ankle bracing practices in ambulatory, corticosteroid-naive boys with Duchenne muscular dystrophy. Muscle Nerve. 2019 Oct 6. [Epub ahead of print] PubMed PMID: 31588574
  • Wicklund MP. The Limb-Girdle Muscular Dystrophies. Continuum (Minneap Minn). 2019 Dec;25(6):1599-1618. PubMed PMID: 31794462
  • Piquet AL, Khan M, Warner JEA, Wicklund MP, Bennett JL, Leehey MA, Seeberger L, Schreiner TL, Paz Soldan MM, Clardy SL. Novel clinical features of glycine receptor antibody syndrome: A series of 17 cases. Neurol Neuroimmunol Neuroinflamm. 2019 Sep;6(5):e592. PubMed PMID: 31355325
  • He C, Lee JS, Cool CD, Wicklund MP, Fischer A. Development of Autoimmune Interstitial Lung Disease in a Patient with Inclusion Body Myositis. Am J Med. 2019 Dec;132(12):e854-e855. PubMed PMID: 31310746
  • Hunter M, Heatwole C, Wicklund M, Weihl CC, Mozaffar T, Statland JM, Johnson NE. Limb-girdle muscular dystrophy: A perspective from adult patients on what matters most. Muscle Nerve. 2019 Oct;60(4):419-424. PubMed PMID: 31298728
  • Xu F, Takahashi H, Tanaka Y, Ichinose S, Niwa S, Wicklund MP, Hirokawa N. KIF1Bß mutations detected in hereditary neuropathy impair IGF1R transport and axon growth. J Cell Biol. 2018 Oct 1;217(10):3480-3496. PubMed PMID: 30126838
  • Kumar A, Asghar S, Kavanagh R, Wicklund MP. Unique presentation of rapidly fluctuating symptoms in a child with congenital myasthenic syndrome due to RAPSN mutation. Muscle Nerve. 2018 Oct;58(4):E23-E24. PubMed PMID: 30028532
  • Crow RA, Hart KA, McDermott MP, Tawil R, Martens WB, Herr BE, McColl E, Wilkinson J, Kirschner J, King WM, Eagle M, Brown MW, Hirtz D, Lochmuller H, Straub V, Ciafaloni E, Shieh PB, Spinty S, Childs AM, Manzur AY, Morandi L, Butterfield RJ, Horrocks I, Roper H, Flanigan KM, Kuntz NL, Mah JK, Morrison L, Darras BT, von der Hagen M, Schara U, Wilichowski E, Mongini T, McDonald CM, Vita G, Barohn RJ, Finkel RS, Wicklund M, McMillan HJ Jr, Hughes I, Pegoraro E, Bryan Burnette W, Howard JF, Thangarajh M, Campbell C, Griggs RC, Bushby K, Guglieri M. A checklist for clinical trials in rare disease: obstacles and anticipatory actions-lessons learned from the FOR-DMD trial. Trials. 2018 May 10;19(1):291. PubMed PMID: 29793540
  • Al-Tahan S, Al-Obeidi E, Yoshioka H, Lakatos A, Weiss L, Grafe M, Palmio J, Wicklund M, Harati Y, Omizo M, Udd B, Kimonis V. Novel valosin-containing protein mutations associated with multisystem proteinopathy. Neuromuscul Disord. 2018 Jun;28(6):491-501. PubMed PMID: 29754758
  • Giampetro D, Ruiz-Velasco V, Pruett A, Wicklund M, Knipe R. The Effect of Propofol on Chronic Headaches in Patients Undergoing Endoscopy. Pain Res Manag. 2018;2018:6018404. PubMed PMID: 29610631
  • Nallamilli BRR, Chakravorty S, Kesari A, Tanner A, Ankala A, Schneider T, da Silva C, Beadling R, Alexander JJ, Askree SH, Whitt Z, Bean L, Collins C, Khadilkar S, Gaitonde P, Dastur R, Wicklund M, Mozaffar T, Harms M, Rufibach L, Mittal P, Hegde M. Genetic landscape and novel disease mechanisms from a large LGMD cohort of 4656 patients. Ann Clin Transl Neurol. 2018 Dec;5(12):1574-1587. PubMed PMID: 30564623
  • Guglieri M, Bushby K, McDermott MP, Hart KA, Tawil R, Martens WB, Herr BE, McColl E, Wilkinson J, Kirschner J, King WM, Eagle M, Brown MW, Willis T, Hirtz D, Shieh PB, Straub V, Childs AM, Ciafaloni E, Butterfield RJ, Horrocks I, Spinty S, Flanigan KM, Kuntz NL, Baranello G, Roper H, Morrison L, Mah JK, Manzur AY, McDonald CM, Schara U, von der Hagen M, Barohn RJ, Campbell C, Darras BT, Finkel RS, Vita G, Hughes I, Mongini T, Pegoraro E, Wicklund M, Wilichowski E, Bryan Burnette W, Howard JF, McMillan HJ, Thangarajh M, Griggs RC. Developing standardized corticosteroid treatment for Duchenne muscular dystrophy. Contemp Clin Trials. 2017 Jul;58:34-39. PubMed PMID: 28450193
  • Ibrahimi M, Nozaki H, Lee A, Onodera O, Reichwein R, Wicklund M, El-Ghanem M. A CARASIL Patient from Americas with Novel Mutation and Atypical Features: Case Presentation and Literature Review. Cerebrovasc Dis. 2017;44(3-4):135-140. PubMed PMID: 28628911
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Professional Memberships

  • American Academy of Neurology, Fellow
  • FSHD Society, Member
  • American Neurological Association, Member
  • Muscle Study Group, Member

Practice Locations

Neurosciences Center - Anschutz
1635 Aurora Ct
4th Floor
Aurora, CO 80045
720-848-2080

UCHealth - Lone Tree Health Center
9548 Park Meadows Drive
Lone Tree, CO 80124
720-848-2200

UCH - Anschutz Outpatient Pavilion
1635 Aurora Ct
Aurora, CO 80045
720-848-0000

Hospital Affiliation
  • University of Colorado Hospital
  • Children's Hospital Colorado

Specialty Information

Specialties
  • Neurology, Board Certification (1997, 2017)
  • Neuromuscular Medicine (2009, 2017)
  • UCNS Clinical Neuromuscular Pathology, Board Certification (2017)
Conditions & Treatments
  • Brain and Nervous System - Neuromuscular Diseases
  • Brain and Nervous System
Clinical Interests
Neuromuscular disorders including: muscular dystrophies, acquired muscle diseases such as dermatomyositis and polymyositis, Charcot-Marie-Tooth disease, acquired peripheral nervous system disorders such as Guillain-Barre syndrome and CIDP, hereditary spastic paraplegias and spinocerebellar ataxias.

Care Philosophy
Delineating the correct diagnosis remains the key to patient care. During this transition into the era of gene-based therapies, accurate diagnosis & optimal treatment of the underlying condition(s), along with other organ system involvement, becomes paramount and often requires a team based approach.

Public Speaking
Yes

General Information

Medical Schools:
  • MD, University of Colorado Denver School of Medicine (1987)
Undergraduate Schools:
  • BA, University of Colorado - Boulder (CO) (1981)
Internships:
  • Dartmouth-Hitchcock Medical Center Program (1988)
Residency Programs:
  • San Antonio Uniformed Services Health Education Consortium (WHMC) Program, Chief Resident, Neurology (1996)
Fellowships:
  • Ohio State University Hospital Program, Neuromuscular Medicine (2001)
Languages: English
Department: Neurology
;