Holly Frost, MD
Assistant Professor, Pediatrics

Photo
Medical School:
  • MD, Medical College of Wisconsin (2010)
Undergraduate School:
  • BS, Michigan Technological University (MI) (2004)
Internship:
  • University of Colorado (Children's Hospital Colorado) Program (2011)
Residency:
  • University of Colorado (Children's Hospital Colorado) Program, Pediatrics (2013)
Languages: English
Department: Pediatrics

Professional Titles

  • Assistant Professor Pediatrics

Recognition & Awards

  • Days of Celebration Poster Award, Denver Health Medical Center (2018)
  • Shining Star Award, Marshfield Clinic (2016)
  • Kass Award, Infectious Disease Society of America (2013)

Teaching

  • Assistant Professor (2019)
    School of Medicine, Pediatrics
    General academic pediatrics; infectious diseases; clinical and translational research

Publications

  • Douglas CM, O' Leary SC, Tomcho MM, Wu FJ, Penny L, Federico SG, Wilson ML, Rinehart DJ, Frost HM. Gonorrhea and chlamydia rates among 12-24 year old patients in an urban health system. Sex Transm Dis. 2020 Sep 29. [Epub ahead of print] PubMed PMID: 33003186
  • Simione M, Frost HM, Cournoyer R, Mini FN, Cassidy J, Craddock C, Moreland J, Wallace J, Metlay J, Kistin CJ, Sease K, Hambidge SJ, Taveras EM. Engaging stakeholders in the adaptation of the Connect for Health pediatric weight management program for national implementation. Implement Sci Commun. 2020;1:55. PubMed PMID: 32885211
  • Frost HM, Becker LF, Knepper BC, Shihadeh KC, Jenkins TC. Antibiotic Prescribing Patterns for Acute Otitis Media for Children 2 Years and Older. J Pediatr. 2020 May;220:109-115.e1. PubMed PMID: 32111379
  • Koester TM, Timothy P, Meece JK, Osborn RA, Frost HM. Suspected Neuro-invasive Powassan Virus Infection in a Pediatric Patient. Clin Med Res. 2020 Aug;18(2-3):95-98. PubMed PMID: 32060042
  • Frost HM, Andersen LM, Fleming-Dutra KE, Norlin C, Czaja CA. Sustaining outpatient antimicrobial stewardship: Do we need to think further outside the box?. Infect Control Hosp Epidemiol. 2020 Mar;41(3):382-384. PubMed PMID: 31918775
  • Frost HM, Knepper BC, Shihadeh KC, Jenkins TC. A Novel Approach to Evaluate Antibiotic Utilization Across the Spectrum of Inpatient and Ambulatory Care and Implications for Prioritization of Antibiotic Stewardship Efforts. Clin Infect Dis. 2020 Apr 10;70(8):1675-1682. PubMed PMID: 31162539
  • Anderson JL, Frost HM. Meece JK. Spontaneous resolution of blastomycosis symptoms caused by B.dermatitidis. Med Mycol Case Rep 2020; 30:43-45
  • Frost HM, Gerber JS, Hersh AL. Antibiotic Recommendations for Acute Otitis Media and Acute Bacterial Sinusitis. Pediatr Infect Dis J. 2019 Feb;38(2):217. PubMed PMID: 30640191
  • Anderson JL, Frost HM, King JP, Meece JK. Racial Differences in Clinical Phenotype and Hospitalization of Blastomycosis Patients. Open Forum Infect Dis. 2019 Nov;6(11):ofz438. PubMed PMID: 31696142
  • Frost HM, Knepper BC, Shihadeh KC, Jenkins TC. A novel approach to evaluate antibiotic utilization across the spectrum of inpatient and ambulatory care and implications for prioritization of antibiotic stewardship efforts. Clin Infect Dis. 2019 Jun 3. [Epub ahead of print] PubMed PMID: 31162539
  • Frost HM, Gerber JS, Hersh AL. Antibiotic Recommendations for Acute Otitis Media and Acute Bacterial Sinusitis. Pediatr Infect Dis J. 2019 Feb;38(2):217. PubMed PMID: 30640191
  • Frost HM, Fritsche TR, Hall MC. Beta-Hemolytic Nongroup A Streptococcal Pharyngitis in Children. J Pediatr. 2019 Mar;206:268-273.e1. PubMed PMID: 30528760
  • Frost HM, Fritsche TR, Hall MC. Beta-Hemolytic Nongroup A Streptococcal Pharyngitis in Children. J Pediatr. 2018 Dec 6. [Epub ahead of print] PubMed PMID: 30528760
  • Frost HM, McLean HQ, Chow BDW. Variability in Antibiotic Prescribing for Upper Respiratory Illnesses by Provider Specialty. J Pediatr. 2018 Dec;203:76-85.e8. PubMed PMID: 30195553
  • Koester TM, Meece JK, Fritsche TR, Frost HM. Infectious Mononucleosis and Lyme Disease as Confounding Diagnoses: A Report of 2 Cases. Clin Med Res. 2018 Dec;16(3-4):66-68. PubMed PMID: 30166498
  • Thomm AM, Schotthoefer AM, Dupuis AP 2nd, Kramer LD, Frost HM, Fritsche TR, Harrington YA, Knox KK, Kehl SC. Development and Validation of a Serologic Test Panel for Detection of Powassan Virus Infection in U.S. Patients Residing in Regions Where Lyme Disease Is Endemic. mSphere. 2018 Jan-Feb;3(1). PubMed PMID: 29359181
  • Schotthoefer AM, Hall MC, Vittala S, Bajwa R, Frost HM. Clinical Presentation and Outcomes of Children With Human Granulocytic Anaplasmosis. J Pediatric Infect Dis Soc. 2018 May 15;7(2):e9-e15. PubMed PMID: 28520981
  • Frost HM, Andersen LM, Monti J, Fleming-Dutra KE, Norlin C, Czaja CA. A quality improvement project to improve delayed antibiotic prescribing for acute otitis media. 2020. [Submitted]
  • O’Leary SC, Rinehart D, Tomcho MM, Thomas-Gale T, Federico SG, Claudia MD, Wu FJ, Penny L, Frost HM. Association of Long Acting Reversible Contraceptives with Sexually Transmitted Infection Testing and Positivity Rates. 2020. [Submitted]
  • Tomcho MM, Lou Y, Douglas CM, O’Leary SC, Rinehart D, Federico SG, Claudia MD, Wu FJ, Penny L, Federico SG, Frost HM. Improving gonorrhea and chlamydia screening in adolescents: A university screening pilot program. 2020. [Submitted]
  • Frost HM. American Academy of Pediatrics Council on School Health Newsletter: Universal Chlamydia Screening in Adolescents. 2020. [In Press]
  • Simione M, Farrar-Muir H, Mini FN, Perkins ME, Lou M, Frost HM, Oray J, Metlay J, Zai AH, Kistin CJ, Sease K, Hambidge SJ, Taveras EM. Implementation of the Connect for Health Pediatric Weight Management Program: Study Protocol and Baseline Characteristics. 2020. [Submitted]
  • Frost HM, Sebastian T, Durfee J, Jenkins TC. Antibiotic Use for Acute Infectious Conjunctivitis in Children and Adolescents. 2020 [Submitted]
View All (23 Total) View Less

Professional Memberships

  • American Academy of Pediatrics, FAAP
  • Society for Healthcare Epidemiology of America, Member

Practice Locations

Denver Health
777 Bannock St
Denver, CO 80204
303-436-6000

Hospital Affiliation
  • University of Colorado Hospital
  • Denver Health Medical Center

Specialty Information

Specialties
  • Pediatrics, Board Certification (2013, 2019)
  • Neonatal Rescucitation Program, Certificate (2018)
  • Pediatric Advanced Life Support, Certificate (2017)
  • Fellowship Government and Community Service-Pediatric Obesity Prevention, Specialized Training (2007)
Care Philosophy
Dr. Frost is a board-certified pediatrician at Denver Health and an Assistant Professor of Pediatrics at the University of Colorado School of Medicine. She completed her medical education at the Medical College of Wisconsin and pediatric residency at the University of Colorado and Children’s Hospital Colorado. Dr. Frost has been in practice for more than 7 years and sees patients of all ages for primary care. Her research and clinical interests focus on infectious diseases in children, including the development of new tests to rapidly diagnose infections and improved treatment options for common infections of childhood. When not in clinic, Dr. Frost enjoys spending time with her two young boys and hiking in the mountains. Dr. Frost strives to provide compassionate, evidence-based care for children and to treat every child in the way she would want others to care for her own children.

General Information

Medical Schools:
  • MD, Medical College of Wisconsin (2010)
Undergraduate Schools:
  • BS, Michigan Technological University (MI) (2004)
Internships:
  • University of Colorado (Children's Hospital Colorado) Program (2011)
Residency Programs:
  • University of Colorado (Children's Hospital Colorado) Program, Pediatrics (2013)
Languages: English
Department: Pediatrics
;