Jose Maria Pacheco, MD
Assistant Professor, Medicine-Medical Oncology

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Medical School:
  • MD, University of Texas Medical Branch School of Medicine (2010)
Undergraduate School:
  • BS, Missouri State University (MO) (2006)
Residency:
  • Washington University/Barnes-Jewish Hospital/St. Louis Children's Hospital, Internal Medicine (2013)
Fellowships:
  • Baylor College of Medicine Program, Hematology and Oncology
Languages: English, Spanish
Department: Medicine-Medical Oncology

Recognition & Awards

  • Harris Health Hero - Award for Excellent Patient Care, Harris Health System - Houston, Texas (2016)
  • Duncan Pilot Project RFA, neoadjuvant avelumab in muscle invasive bladder cancer, Baylor College of Medicine (2016)

Research Interests

Concerning academic activity, I have given presentations at the Santa Monica Targeted Therapies in Lung Cancer meeting, the International Association for Study of Lung Cancer World Conference on Lung Cancer Annual meeting, the Lungevity International Lung Cancer Survivorship Conference and as part of numerous lung cancer continuing medical education series. I have authored or coauthored 4 book chapters, as well as published nearly 30 articles in peer-reviewed journals. I will be serving as study chair on a cooperative group trial of a novel immunotherapy combination in patients progressing on PD-1 axis inhibitors. I am currently serving as Principal Investigator on several clinical trials at the cancer center.

Publications

  • Li BT, Smit EF, Goto Y, Nakagawa K, Udagawa H, Mazières J, Nagasaka M, Bazhenova L, Saltos AN, Felip E, Pacheco JM, Pérol M, Paz-Ares L, Saxena K, Shiga R, Cheng Y, Acharyya S, Vitazka P, Shahidi J, Planchard D, Jänne PA. Trastuzumab Deruxtecan in HER2 -Mutant Non-Small-Cell Lung Cancer. N Engl J Med. 2021 Sep 18. [Epub ahead of print] PubMed PMID: 34534430
  • Pacheco JM. Mobocertinib: A Potential Treatment for NSCLC with EGFR Exon 20 Insertions. Cancer Discov. 2021 Jul;11(7):1617-1619. PubMed PMID: 34284994
  • Carcamo B, Bista R, Wilson H, Reddy P, Pacheco J. Rapid Response to Lorlatinib in a Patient With TFG-ROS1 Fusion Positive Inflammatory Myofibroblastic Tumor of the Chest Wall Metastatic to the Brain and Refractory to First and Second Generation ROS1 Inhibitors. J Pediatr Hematol Oncol. 2021 Jul 1;43(5):e718-e722. PubMed PMID: 34157012
  • Pacheco J, Schenk EL, Bunn PA. Optimal Therapy for Advanced Non-Small Cell Lung Cancer Without Driver Alterations. JNCI Cancer Spectr. 2021 Jun;5(3):pkab014. PubMed PMID: 34085000
  • Pacheco JM, Schenk EL. CD73 and Adenosine Receptor Signaling as a Potential Therapeutic Target in EGFR-Mutated NSCLC. J Thorac Oncol. 2021 Apr;16(4):509-511. PubMed PMID: 33781438
  • Bai S, Tian T, Pacheco JM, Tachihara M, Hu P, Zhang J. Immune-related adverse event profile of combination treatment of PD-(L)1 checkpoint inhibitors and bevacizumab in non-small cell lung cancer patients: data from the FDA adverse event reporting system. Transl Lung Cancer Res. 2021 Jun;10(6):2614-2624. PubMed PMID: 34295666
  • Pacheco J, Bunn PA. Advancements in Small-cell Lung Cancer: The Changing Landscape Following IMpower-133. Clin Lung Cancer. 2019 Jan 2. [Epub ahead of print] PubMed PMID: 30686680
  • Pacheco JM, Gao D, Smith D, Purcell WT, Hancock M, Bunn PA, Robin TP, Liu AK, Karam S, Gaspar LE, Kavanagh BD, Rusthoven CG, Aisner DL, Doebele RC, Camidge DR. Natural history and factors associated with overall survival in stage IV ALK rearranged non-small-cell lung cancer. J Thorac Oncol. 2018 Dec 29. [Epub ahead of print] PubMed PMID: 30599201
  • Patil T, Pacheco JM. Miliary Metastases in Non-Small-Cell Lung Cancer. N Engl J Med. 2018 Nov 15;379(20):1945. PubMed PMID: 30428292
  • Pacheco JM, Camidge DR. Antibody drug conjugates in thoracic malignancies. Lung Cancer. 2018 Oct;124:260-269. PubMed PMID: 30268471
  • Robin TP, Camidge DR, Stuhr K, Nath SK, Breeze RE, Pacheco JM, Liu AK, Gaspar LE, Purcell WT, Doebele RC, Kavanagh BD, Rusthoven CG. Excellent Outcomes with Radiosurgery for Multiple Brain Metastases in ALK and EGFR Driven Non-Small Cell Lung Cancer. J Thorac Oncol. 2018 May;13(5):715-720. PubMed PMID: 29269007
  • Pacheco JM, Camidge DR. KEYNOTE-028: how do we use immunotherapy in small cell lung cancer?. Transl Lung Cancer Res. 2017 Dec;6(Suppl 1):S84-S87. PubMed PMID: 29299419
  • Pacheco JM, Dimou A, Bunn PA. Advances in lung cancer. Oncotarget. 2017 Oct 3;8(45):78247-78248. PubMed PMID: 29108218
  • Robin TP, Camidge DR, Stuhr K, Nath SK, Breeze RE, Pacheco J, Liu AK, Gaspar LE, Purcell WT, Doebele RC, Kavanagh BD, Rusthoven CG. Excellent Outcomes with Radiosurgery for Multiple Brain Metastases in Oncogene-Addicted Non-Small-Cell Lung Cancer. J Thorac Oncol. 2017 Dec 18. [Epub ahead of print] PubMed PMID: 29269007
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Practice Locations

Lung Cancer Clinic - Anschutz
1665 Aurora Ct
Anschutz Cancer Pavilion
Aurora, CO 80045
720-848-0300

University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

UCH - Cancer Center
1665 Aurora Ct
Aurora, CO 80045
720-848-0300

Hospital Affiliation
  • University of Colorado Hospital
Center Affiliations

Specialty Information

Specialties
  • Medical Oncology
Conditions & Treatments
  • Cancers - Lung Cancer
  • Cancers
Clinical Interests
I was born in in Springfield, Missouri. I served as an Internal Medicine faculty at the Saint Louis Veterans Hospital and Barnes Jewish Hospital for one year before undergoing a Hematology and Oncology Fellowship. In 2017, I joined the CU Anschutz family as an Assistant Professor in Thoracic Oncology and Developmental Therapeutics.

Personal Interests
Outside of work, I enjoy athletic activities and trying new cusine.

General Information

Medical Schools:
  • MD, University of Texas Medical Branch School of Medicine (2010)
Undergraduate Schools:
  • BS, Missouri State University (MO) (2006)
Residency Programs:
  • Washington University/Barnes-Jewish Hospital/St. Louis Children's Hospital, Internal Medicine (2013)
Fellowships:
  • Baylor College of Medicine Program, Hematology and Oncology (0001)
Languages: English, Spanish
Department: Medicine-Medical Oncology
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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