Masanori Hayashi, MD
Assistant Professor, Pediatrics-Heme/Onc and Bone Marrow Transplantation

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Medical School:
  • MD, Keio University School of Medicine, Tokyo, Japan (2005)
Internship:
  • Duke University Hospital Program (2008)
Residency:
  • Duke University Hospital Program, Pediatrics (2010)
Fellowships:
  • National Cancer Institute, Pediatric Hematology / Oncology (2014)
  • Johns Hopkins University School of Medicine Program, Pediatric Hematology / Oncology (2016)
Languages: English, Japanese
Department: Pediatrics-Heme/Onc and Bone Marrow Transplantation

Recognition & Awards

  • SARC Sarcoma Spore Career Development Award, SARC (2015)
    The SARC Sarcoma Spore Career Development Award is awarded to two sarcoma translational researchers every year, to ensure the continual renewal of high-quality scientific endeavors in sarcoma research.
  • Duke Pediatrics Deborah Kredich Memorial Award for the most influential resident of the year for house staff education, Duke University Department of Pediatrics (2010)
    Selected by peers through voting, this award is awarded to the resident recognized as the most influential in resident education.

Teaching

  • Assistant Professor (2017)
    School of Medicine, Pediatrics

Publications

  • Bodlak A, Chang K, Channel J, Treece AL, Donaldson N, Cost CR, Garrington TP, Greffe B, Luna-Fineman S, Sopfe J, Loeb DM, Hayashi M. Circulating Plasma Tumor DNA Is Superior to Plasma Tumor RNA Detection in Ewing Sarcoma Patients: ptDNA and ptRNA in Ewing Sarcoma. J Mol Diagn. 2021 Jul;23(7):872-881. PubMed PMID: 33887462
  • Oike N, Kawashima H, Ogose A, Hatano H, Ariizumi T, Yamagishi T, Murayama Y, Umezu H, Imai C, Hayashi M, Endo N. Human leukocyte antigen I is significantly downregulated in patients with myxoid liposarcomas. Cancer Immunol Immunother. 2021 Apr 24. [Epub ahead of print] PubMed PMID: 33893830
  • Brechbuhl HM, Vinod-Paul K, Gillen AE, Kopin EG, Gibney K, Elias AD, Hayashi M, Sartorius CA, Kabos P. Analysis of circulating breast cancer cell heterogeneity and interactions with peripheral blood mononuclear cells. Mol Carcinog. 2020 Oct;59(10):1129-1139. PubMed PMID: 32822091
  • Oesterheld JE, Reed DR, Setty BA, Isakoff MS, Thompson P, Yin H, Hayashi M, Loeb DM, Smith T, Makanji R, Fridley BL, Wagner LM. Phase II trial of gemcitabine and nab-paclitaxel in patients with recurrent Ewing sarcoma: A report from the National Pediatric Cancer Foundation. Pediatr Blood Cancer. 2020 Jul;67(7):e28370. PubMed PMID: 32386107
  • Reed DR, Metts J, Pressley M, Fridley BL, Hayashi M, Isakoff MS, Loeb DM, Makanji R, Roberts RD, Trucco M, Wagner LM, Alexandrow MG, Gatenby RA, Brown JS. An evolutionary framework for treating pediatric sarcomas. Cancer. 2020 Jun 1;126(11):2577-2587. PubMed PMID: 32176331
  • AACR oral presentation A CRISPR drop-out screen combined with high-throughput drug screening identifies genetic and therapeutic vulnerabilities of BCOR-CCNB3 fusion positive sarcomas. Naoki Oike, Hiroyuki Kawashima, Akira Ogose, Takashi Ariizumi, Yudai Murayama, Hajime Umezu, Molishree Joshi, Colin Sempeck, Bridget Samford, Deandra Walker, Avery Bodlak, Naoto Endo, Masanori Hayashi
  • Nellan A, Bodlak A, Mirsky DM, Mulcahy Levy J, Garrington TP, Foreman NK, Gilani A, Hayashi M. ddPCR Analysis Reveals BRAF V600E Mutations Are Infrequent in Isolated Pituitary Langerhans Cell Histiocytosis Patients. J Neuropathol Exp Neurol. 2020 Sep 15:nlaa091. doi: 10.1093/jnen/nlaa091. Epub ahead of print. PMID: 32930721.
  • Borinstein SC, Steppan D, Hayashi M, Loeb DM, Isakoff MS, Binitie O, Brohl AS, Bridge JA, Stavas M, Shinohara ET, Meyer WH, Reed DR, Wagner LM. Consensus and controversies regarding the treatment of rhabdomyosarcoma. Pediatr Blood Cancer. 2018 Feb;65(2). PubMed PMID: 28905489
  • Reed DR, Hayashi M, Wagner L, Binitie O, Steppan DA, Brohl AS, Shinohara ET, Bridge JA, Loeb DM, Borinstein SC, Isakoff MS. Treatment pathway of bone sarcoma in children, adolescents, and young adults. Cancer. 2017 Jun 15;123(12):2206-2218. PubMed PMID: 28323337
  • Llosa NJ, Cooke KR, Chen AR, Gamper CJ, Klein OR, Zambidis ET, Luber B, Rosner G, Siegel N, Holuba MJ, Robey N, Hayashi M, Jones RJ, Fuchs E, Holdhoff M, Loeb DM, Symons HJ. Reduced-Intensity Haploidentical Bone Marrow Transplantation with Post-Transplant Cyclophosphamide for Solid Tumors in Pediatric and Young Adult Patients. Biol Blood Marrow Transplant. 2017 Aug 12. [Epub ahead of print] PubMed PMID: 28807769
  • Borinstein SC, Steppan D, Hayashi M, Loeb DM, Isakoff MS, Binitie O, Brohl AS, Bridge JA, Stavas M, Shinohara ET, Meyer WH, Reed DR, Wagner LM. Consensus and controversies regarding the treatment of rhabdomyosarcoma. Pediatr Blood Cancer. 2017 Sep 14. [Epub ahead of print] PubMed PMID: 28905489
  • Hayashi M, Zhu P, McCarty G, Meyer CF, Pratilas CA, Levin A, Morris CD, Albert CM, Jackson KW, Tang CM, Loeb DM. Size-based detection of sarcoma circulating tumor cells and cell clusters. Oncotarget. 2017 Oct 3;8(45):78965-78977. PubMed PMID: 29108279
  • Hayashi M, Baker A, Goldstein SD, Albert CM, Jackson KW, McCarty G, Kahlert UD, Loeb DM. Inhibition of porcupine prolongs metastasis free survival in a mouse xenograft model of Ewing sarcoma. Oncotarget. 2017 Oct 3;8(45):78265-78276. PubMed PMID: 29108227
  • Hayashi M, Zhu P, McCarty G, Meyer CF, Pratilas CA, Levin A, Morris CD, Albert CM, Jackson KW, Tang CM, Loeb DM. Size-based detection of sarcoma circulating tumor cells and cell clusters. Oncotarget. 2017 Oct 3;8(45):78965-78977. PubMed PMID: 29108279
  • Hayashi M, Baker A, Goldstein SD, Albert CM, Jackson KW, McCarty G, Kahlert UD, Loeb DM. Inhibition of porcupine prolongs metastasis free survival in a mouse xenograft model of Ewing sarcoma. Oncotarget. 2017 Oct 3;8(45):78265-78276. PubMed PMID: 29108227
  • Llosa NJ, Cooke KR, Chen AR, Gamper CJ, Klein OR, Zambidis ET, Luber B, Rosner G, Siegel N, Holuba MJ, Robey N, Hayashi M, Jones RJ, Fuchs E, Holdhoff M, Loeb DM, Symons HJ. Reduced-Intensity Haploidentical Bone Marrow Transplantation with Post-Transplant Cyclophosphamide for Solid Tumors in Pediatric and Young Adult Patients. Biol Blood Marrow Transplant. 2017 Dec;23(12):2127-2136. PubMed PMID: 28807769
  • Reed DR, Hayashi M, Wagner L, Binitie O, Steppan DA, Brohl AS, Shinohara ET, Bridge JA, Loeb DM, Borinstein SC, Isakoff MS. Treatment pathway of bone sarcoma in children, adolescents, and young adults. Cancer. 2017 Jun 15;123(12):2206-2218. PubMed PMID: 28323337
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Professional Memberships

  • Children's Oncology Group, Member, Ewing Sarcoma biology committee
  • Connective Tissue Oncology Society, Member
  • American Association for Cancer Research, Member
  • American Society of Clinical Oncology, Member

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation
  • Children's Hospital Colorado
Center Affiliations

Specialty Information

Specialties
  • Pediatrics, Board Certification (2010)
  • Pediatric Hematology / Oncology, Board Certification (2017)
Conditions & Treatments
  • Cancers - Pediatric Cancer
  • Cancers
  • Cancers - Sarcoma
  • Cancers - Bone Cancer
Care Philosophy
I am committed to a team based approach to the care of my patients, which values the participation of the various members of the medical team and most importantly the patient and family.

General Information

Medical Schools:
  • MD, Keio University School of Medicine, Tokyo, Japan (2005)
Internships:
  • Duke University Hospital Program (2008)
Residency Programs:
  • Duke University Hospital Program, Pediatrics (2010)
Fellowships:
  • National Cancer Institute, Pediatric Hematology / Oncology (2014)
  • Johns Hopkins University School of Medicine Program, Pediatric Hematology / Oncology (2016)
Languages: English, Japanese
Department: Pediatrics-Heme/Onc and Bone Marrow Transplantation
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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