Yi Sun, PhD
Research Instructor, Surgery-Surgical Oncology

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Medical School:
  • MD, Peking University Health Science Center (2000)
Languages: English, Mandarin
Department: Surgery-Surgical Oncology

Professional Titles

  • Visiting Assistant Professor

Publications

  • Structural insight into CD93 recognition by IGFBP7 Yueming Xu, Yi Sun, Yuwen Zhu, Gaojie Song PMID: 37333140 PMCID: PMC10274810 DOI: 10.1101/2023.06.07.543655
  • Torphy RJ, Sun Y, Lin R, Caffrey-Carr A, Fujiwara Y, Ho F, Miller EN, McCarter MD, Lyons TR, Schulick RD, Kedl RM, Zhu Y. GPR182 limits antitumor immunity via chemokine scavenging in mouse melanoma models. Nat Commun. 2022 Jan 10;13(1):97. PubMed PMID: 35013216
  • Sun Y, Chen W, Torphy RJ, Yao S, Zhu G, Lin R, Lugano R, Miller EN, Fujiwara Y, Bian L, Zheng L, Anand S, Gao F, Zhang W, Ferrara SE, Goodspeed AE, Dimberg A, Wang XJ, Edil BH, Barnett CC, Schulick RD, Chen L, Zhu Y. Blockade of the CD93 pathway normalizes tumor vasculature to facilitate drug delivery and immunotherapy. Sci Transl Med. 2021 Jul 28;13(604):eabc8922. doi: 10.1126/scitranslmed.abc8922. PMID: 34321321.
  • Fujiwara Y, Torphy RJ, Sun Y, Miller EN, Ho F, Borcherding N, Wu T, Torres RM, Zhang W, Schulick RD, Zhu Y. The GPR171 pathway suppresses T cell activation and limits antitumor immunity. Nat Commun. 2021 Oct 6;12(1):5857. doi: 10.1038/s41467-021-26135-9. PMID: 34615877; PMCID: PMC8494883.
  • Yao C, Lou G, Sun HW, Zhu Z, Sun Y, Chen Z, Chauss D, Moseman EA, Cheng J, D'Antonio MA, Shi W, Shi J, Kometani K, Kurosaki T, Wherry EJ, Afzali B, Gattinoni L, Zhu Y, McGavern DB, O'Shea JJ, Schwartzberg PL, Wu T. BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8( ) T cells. Nat Immunol. 2021 Mar;22(3):370-380. PubMed PMID: 33574619
  • Tian Y, Sun Y, Gao F, Koenig MR, Sunderland A, Fujiwara Y, Torphy RJ, Chen L, Edil BH, Schulick RD, Zhu Y. CD28H expression identifies resident memory CD8 + T cells with less cytotoxicity in human peripheral tissues and cancers. Oncoimmunology. 2019;8(2):e1538440. PubMed PMID: 30713797
  • Fujiwara Y, Sun Y, Torphy RJ, He J, Yanaga K, Edil BH, Schulick RD, Zhu Y. Pomalidomide Inhibits PD-L1 Induction to Promote Antitumor Immunity. Cancer Res. 2018 Dec 1;78(23):6655-6665. PubMed PMID: 30315115
  • Sun Y, Torphy RJ, Zhu Y. Depletion of tumor associated macrophages by anti-BAG3 treatment complements PD-1 blockade in pancreatic cancer. Ann Pancreat Cancer
  • Li Y, Si L, Zhai Y, Hu Y, Hu Z, Bei JX, Xie B, Ren Q, Cao P, Yang F, Song Q, Bao Z, Zhang H, Han Y, Wang Z, Chen X, Xia X, Yan H, Wang R, Zhang Y, Gao C, Meng J, Tu X, Liang X, Cui Y, Liu Y, Wu X, Li Z, Wang H, Li Z, Hu B, He M, Gao Z, Xu X, Ji H, Yu C, Sun Y, Xing B, Yang X, Zhang H, Tan A, Wu C, Jia W, Li S, Zeng YX, Shen H, He F, Mo Z, Zhang H, Zhou G. Genome-wide association study identifies 8p21.3 associated with persistent hepatitis B virus infection among Chinese. Nat Commun. 2016 May 31;7:11664. PubMed PMID: 27244555
  • Liu W, Wang K, Bao Q, Sun Y, Xing BC. Hepatic resection provided long-term survival for patients with intermediate and advanced-stage resectable hepatocellular carcinoma. World J Surg Oncol. 2016 Mar 2;14:62. PubMed PMID: 26936459
  • Liu W, Zhou JG, Sun Y, Zhang L, Xing BC. The role of neoadjuvant chemotherapy for resectable colorectal liver metastases: a systematic review and meta-analysis. Oncotarget. 2016 Jun 14;7(24):37277-37287. PubMed PMID: 27074564
  • Liu W, Zhou JG, Sun Y, Zhang L, Xing BC. Hepatic Resection Improved the Long-Term Survival of Patients with BCLC Stage B Hepatocellular Carcinoma in Asia: a Systematic Review and Meta-Analysis. J Gastrointest Surg. 2015 Jul;19(7):1271-80. PubMed PMID: 25943910
  • Liu W, Sun Y, Zhang L, Xing BC. Negative surgical margin improved long-term survival of colorectal cancer liver metastases after hepatic resection: a systematic review and meta-analysis. Int J Colorectal Dis. 2015 Oct;30(10):1365-73. PubMed PMID: 26198997
  • Liu W, Yan X, Wang K, Bao Q, Sun Y, Wang H, Jin K, Xing B. [Risk factor analysis of early recurrence after resection of colorectal liver metastasis]. Zhonghua Wei Chang Wai Ke Za Zhi. 2015 Nov;18(11):1098-101. PubMed PMID: 26616801
  • Jin K, Yan X, Wang K, Bao Q, Sun Y, Wang H, Xing B. [Prognostic significance of clinical risk score system after resection of hepatic metastases from colorectal cancer]. Zhonghua Zhong Liu Za Zhi. 2015 Dec;37(12):913-6. PubMed PMID: 26887620
  • Liu M, Wang K, Sun Y, Bao Q, Wang H, Jin K, Xing B. [Effect of hepatitis on surgical treatment and prognosis of colorectal liver metastasis]. Zhonghua Wei Chang Wai Ke Za Zhi. 2015 Jul;18(7):680-3. PubMed PMID: 26211771
  • Wang H, Wang K, Bao Q, Sun Y, Jin K, Yan X, Xing B. [Impact of overweight on postoperative complications and oncological outcome after radical hepatectomy for metastatic colorectal cancer]. Zhonghua Zhong Liu Za Zhi. 2015 Mar;37(3):200-3. PubMed PMID: 25975789
  • Liu W, Yan XL, Wang K, Bao Q, Sun Y, Xing BC. The outcome of liver resection and lymphadenectomy for hilar lymph node involvement in colorectal cancer liver metastases. Int J Colorectal Dis. 2014 Jun;29(6):737-45. PubMed PMID: 24743847
  • Jiang Q, Yan X, Wang K, Bao Q, Sun Y, Wang H, Jin K, Xing B. [Evaluation of long-term survival after hepatic resection for metastatic colorectal cancer-a multifactorial model of 191 patients]. Zhonghua Wai Ke Za Zhi. 2014 Mar;52(3):171-4. PubMed PMID: 24785453
  • Wang L, Yan X, Wang K, Bao Q, Sun Y, Wang H, Jin K, Xing B. [Simultaneous versus staged liver resection of synchronous liver metastasis from colorectal cancer]. Zhonghua Wei Chang Wai Ke Za Zhi. 2014 Oct;17(10):1009-13. PubMed PMID: 25341909
  • Sun Y, Yan X, Wang K, Bao Q, Wang H, Jin K, Xing B. [Predictors and outcomes of recurrence after resection of colorectal liver metastases]. Zhonghua Yi Xue Za Zhi. 2014 Apr 29;94(16):1232-6. PubMed PMID: 24924887
  • Liu W, Yan XL, Wang K, Bao Q, Sun Y, Wang HW, Jin KM, Xing BC. [Surgical outcomes of second liver resections for recurrent hepatic metastases from colorectal cancer]. Zhonghua Yi Xue Za Zhi. 2013 Jul 23;93(28):2183-5. PubMed PMID: 24169324
  • Sun Y, Wu ZY, Hao CY, Huang XF, Wang K, Bao Q, Qian HG, Xing BC. [Clinical analysis of curative resection with hemihepatectomy for advanced hilar cholangiocarcinoma]. Zhonghua Yi Xue Za Zhi. 2008 Feb 26;88(8):527-30. PubMed PMID: 18649767
  • Sun W, Xing B, Sun Y, Du X, Lu M, Hao C, Lu Z, Mi W, Wu S, Wei H, Gao X, Zhu Y, Jiang Y, Qian X, He F. Proteome analysis of hepatocellular carcinoma by two-dimensional difference gel electrophoresis: novel protein markers in hepatocellular carcinoma tissues. Mol Cell Proteomics. 2007 Oct;6(10):1798-808. PubMed PMID: 17627933
  • Xing BC, Sun Y, Bao Q, Qian HG, Hao CY, Huang XF, Wang Y, Gu J, Ji JF. [Spleen-preserving distal pancreatectomy in treatment of solid-pseudopapillary neoplasm]. Zhonghua Yi Xue Za Zhi. 2006 Mar 14;86(10):690-2. PubMed PMID: 16681929
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Specialty Information

Specialties
  • Surgical Oncology, Beijing, China, License (2001)

General Information

Medical Schools:
  • MD, Peking University Health Science Center (2000)
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Languages: English, Mandarin
Department: Surgery-Surgical Oncology
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