Erin Schenk, MD, PhD
Assistant Professor, Medicine-Medical Oncology

Photo
Medical School:
  • MD, Mayo Medical School (2011)
Graduate School :
  • PhD, Mayo Graduate School (2011)
Residency:
  • College of Medicine, Mayo Clinic Program, Internal Medicine (2014)
Fellowships:
  • College of Medicine, Mayo Clinic (Rochester) Program, Hematology and Oncology (2018)
Languages: English
Department: Medicine-Medical Oncology

Professional Titles

  • Assistant Professor of Medicine, Division of Medical Oncology

Recognition & Awards

  • LUNGevity Career Development Award, LUNGevity (2021)
    This research grant provides significant funding for 3 years to promising early career investigators engaged in lung cancer research.
  • Paul Calabresi Clinical Oncology Scholar, University of Colorado Cancer Center (2019)
  • Finalist, Immuno-Oncology Young Investigators' Forum (2018)
    Houston, TX
  • Outstanding Fellow Award, Highest Rated and Top Abstract, Minnesota Society of Clinical Oncology (2018)
    Minneapolis, MN
  • International Association for the Study of Lung Cancer (IASLC) Academy Award, IASLC (2018)
    Toronto, Canada
  • IASLC Academy Award, IASLC (2017)
    Yokohama, Japan

Research Interests

My laboratory studies the lung cancer tumor microenvironment, a diverse collection of cell types that can be found in and around lung tumors. We are focused on the immune cells within the tumor and how specific subtypes can contribute to treatment resistance. Ultimately, we hope to use our findings to improve therapy for patients with lung cancer.

Publications

  • Schenk EL, Patil T, Pacheco J, Bunn PA Jr. 2020 Innovation-Based Optimism for Lung Cancer Outcomes. Oncologist. 2021 Mar;26(3):e454-e472. PubMed PMID: 33179378
  • Pacheco J, Schenk EL, Bunn PA. Optimal Therapy for Advanced Non-Small Cell Lung Cancer Without Driver Alterations. JNCI Cancer Spectr. 2021 Jun;5(3):pkab014. PubMed PMID: 34085000
  • Pacheco JM, Schenk EL. CD73 and Adenosine Receptor Signaling as a Potential Therapeutic Target in EGFR-Mutated NSCLC. J Thorac Oncol. 2021 Apr;16(4):509-511. PubMed PMID: 33781438
  • Johnson AM, Boland JM, Wrobel J, Klezcko EK, Weiser-Evans M, Hopp K, Heasley L, Clambey ET, Jordan K, Nemenoff RA, Schenk EL. Cancer Cell-Specific Major Histocompatibility Complex II Expression as a Determinant of the Immune Infiltrate Organization and Function in the NSCLC Tumor Microenvironment. J Thorac Oncol. 2021 May 25. [Epub ahead of print] PubMed PMID: 34048945
  • Ng TL, Johnson A, Nemenoff RA, Hsieh E, Osypuk AA, van Bokhoven A, Li H, Camidge DR, Schenk EL. Prospective Observational Study Revealing Early Pulmonary Function Changes Associated With Brigatinib Initiation. J Thorac Oncol. 2020 Dec 9. [Epub ahead of print] PubMed PMID: 33307191
  • Camidge DR, Schenk EL. Blood-Based Biomarkers for Predicting Immunotherapy Benefit in Lung Cancer. Cell. 2020 Oct 15;183(2):303-304. PubMed PMID: 33064985
  • Maynard A, McCoach CE, Rotow JK, Harris L, Haderk F, Kerr DL, Yu EA, Schenk EL, Tan W, Zee A, Tan M, Gui P, Lea T, Wu W, Urisman A, Jones K, Sit R, Kolli PK, Seeley E, Gesthalter Y, Le DD, Yamauchi KA, Naeger DM, Bandyopadhyay S, Shah K, Cech L, Thomas NJ, Gupta A, Gonzalez M, Do H, Tan L, Bacaltos B, Gomez-Sjoberg R, Gubens M, Jahan T, Kratz JR, Jablons D, Neff N, Doebele RC, Weissman J, Blakely CM, Darmanis S, Bivona TG. Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing. Cell. 2020 Sep 3;182(5):1232-1251.e22. PubMed PMID: 32822576
  • Johnson AM, Bullock BL, Neuwelt AJ, Poczobutt JM, Kaspar RE, Li HY, Kwak JW, Hopp K, Weiser-Evans MCM, Heasley LE, Schenk EL, Clambey ET, Nemenoff RA. Cancer Cell-Intrinsic Expression of MHC Class II Regulates the Immune Microenvironment and Response to Anti-PD-1 Therapy in Lung Adenocarcinoma. J Immunol. 2020 Apr 15;204(8):2295-2307. PubMed PMID: 32179637
  • Failing JJ, Ho TP, Yadav S, Majithia N, Riaz IB, Shin JY, Schenk EL, Xie H. Safety of Influenza Vaccine in Patients With Cancer Receiving Pembrolizumab. JCO Oncol Pract. 2020 Jul;16(7):e573-e580. PubMed PMID: 32048920
  • Patil T, Mushtaq R, Marsh S, Azelby C, Pujara M, Davies KD, Aisner DL, Purcell WT, Schenk EL, Pacheco JM, Bunn PA, Camidge DR, Doebele RC. Clinicopathologic Characteristics, Treatment Outcomes, and Acquired Resistance Patterns of Atypical EGFR Mutations and HER2 Alterations in Stage IV Non-Small-Cell Lung Cancer. Clin Lung Cancer. 2020 May;21(3):e191-e204. PubMed PMID: 31859066
  • Schenk EL, Mandrekar SJ, Dy GK, Aubry MC, Tan AD, Dakhil SR, Sachs BA, Nieva JJ, Bertino E, Lee Hann C, Schild SE, Wadsworth TW, Adjei AA, Molina JR. A Randomized Double-Blind Phase II Study of the Seneca Valley Virus (NTX-010) versus Placebo for Patients with Extensive-Stage SCLC (ES SCLC) Who Were Stable or Responding after at Least Four Cycles of Platinum-Based Chemotherapy: North Central Cancer Treatment Group (Alliance) N0923 Study. J Thorac Oncol. 2020 Jan;15(1):110-119. PubMed PMID: 31605793
  • Patil T, Mushtaq R, Marsh S, Azelby C, Pujara M, Davies KD, Aisner DL, Purcell WT, Schenk EL, Pacheco JM, Bunn PA, Camidge DR, Doebele RC. Clinicopathologic Characteristics, Treatment Outcomes, and Acquired Resistance Patterns of Atypical EGFR Mutations and HER2 Alterations in Stage IV Non-Small-Cell Lung Cancer. Clin Lung Cancer. 2019 Nov 21. [Epub ahead of print] PubMed PMID: 31859066
  • Kleczko EK, Kwak JW, Schenk EL, Nemenoff RA. Targeting the Complement Pathway as a Therapeutic Strategy in Lung Cancer. Front Immunol. 2019;10:954. PubMed PMID: 31134065
  • Bullock BL, Kimball AK, Poczobutt JM, Neuwelt AJ, Li HY, Johnson AM, Kwak JW, Kleczko EK, Kaspar RE, Wagner EK, Hopp K, Schenk EL, Weiser-Evans MC, Clambey ET, Nemenoff RA. Tumor-intrinsic response to IFN? shapes the tumor microenvironment and anti-PD-1 response in NSCLC. Life Sci Alliance. 2019 Jun;2(3). PubMed PMID: 31133614
  • Pacheco JM, Camidge DR, Doebele RC, Schenk E. A Changing of the Guard: Immune Checkpoint Inhibitors With and Without Chemotherapy as First Line Treatment for Metastatic Non-small Cell Lung Cancer. Front Oncol. 2019;9:195. PubMed PMID: 30984621
  • Bunn PA Jr, Schenk E, Pacheco J, Dimou A. New Developments in Neoadjuvant Therapy for Lung Cancer. Oncology (Williston Park). 2019 Mar 13;33(3):101-6, 109. PubMed PMID: 30866032
  • Pacheco J, Schenk E. CDK4/6 inhibition alone and in combination for non-small cell lung cancer. Oncotarget. 2019 Jan 18;10(6):618-619. PubMed PMID: 30774754
View All (17 Total) View Less

Professional Memberships

  • IASLC, Member
  • American Society of Clinical Oncology (ASCO), Member
  • American Association for Cancer Research (AACR), Member

Practice Locations

Lung Cancer Clinic - Anschutz
1665 Aurora Ct
Anschutz Cancer Pavilion
Aurora, CO 80045
720-848-0300

Hospital Affiliation
  • University of Colorado Hospital
Center Affiliations

Specialty Information

Specialties
  • Medical Oncology, Board Certification (2018)
  • Hematology, Board Certification (2018)
  • Internal Medicine, Board Certification (2014)
Conditions & Treatments
  • Cancers - Lung Cancer
  • Cancers
Volunteer Activities
I volunteer as a physician preceptor at the DAWN Clinic, a free clinic run by students to help the underserved community in Aurora, CO.

Public Speaking
Yes

General Information

Medical Schools:
  • MD, Mayo Medical School (2011)
Graduate Schools:
  • PhD, Mayo Graduate School (2011)
Residency Programs:
  • College of Medicine, Mayo Clinic Program, Internal Medicine (2014)
Fellowships:
  • College of Medicine, Mayo Clinic (Rochester) Program, Hematology and Oncology (2018)
Languages: English
Department: Medicine-Medical Oncology
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

Update My Profile
;