Breelyn Wilky, MD
Visiting Associate Professor, Medicine-Medical Oncology

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Medical School:
  • MD, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School (2006)
Undergraduate School:
  • BS, Bates College (ME) (2001)
Internship:
  • Johns Hopkins University School of Medicine Program (2007)
Residency:
  • Johns Hopkins University School of Medicine Program, Internal Medicine (2009)
Fellowships:
  • Johns Hopkins University School of Medicine Program, Medical Oncology (2013)
Languages: English
Department: Medicine-Medical Oncology

Professional Titles

  • Visiting Associate Professor, Medicine-Medical Oncology
  • Director of Sarcoma Translational Research

Publications

  • Florou V, Rosenberg AE, Wieder E, Komanduri KV, Kolonias D, Uduman M, Castle JC, Buell JS, Trent JC, Wilky BA. Correction to: Angiosarcoma patients treated with immune checkpoint inhibitors: a case series of seven patients from a single institution. J Immunother Cancer. 2019 Nov 6;7(1):285. PubMed PMID: 31694703
  • Ramachandran I, Lowther DE, Dryer-Minnerly R, Wang R, Fayngerts S, Nunez D, Betts G, Bath N, Tipping AJ, Melchiori L, Navenot JM, Glod J, Mackall CL, D'Angelo SP, Araujo DM, Chow WA, Demetri GD, Druta M, Van Tine BA, Grupp SA, Abdul Razak AR, Wilky B, Iyengar M, Trivedi T, Winkle EV, Chagin K, Amado R, Binder GK, Basu S. Systemic and local immunity following adoptive transfer of NY-ESO-1 SPEAR T cells in synovial sarcoma. J Immunother Cancer. 2019 Oct 24;7(1):276. PubMed PMID: 31651363
  • Kerr DA, Pinto A, Subhawong TK, Wilky BA, Schlumbrecht MP, Antonescu CR, Nielsen GP, Rosenberg AE. Pericytoma With t(7;12) and ACTB-GLI1 Fusion: Reevaluation of an Unusual Entity and its Relationship to the Spectrum of GLI1 Fusion-related Neoplasms. Am J Surg Pathol. 2019 Dec;43(12):1682-1692. PubMed PMID: 31567194
  • Florou V, Rosenberg AE, Wieder E, Komanduri KV, Kolonias D, Uduman M, Castle JC, Buell JS, Trent JC, Wilky BA. Angiosarcoma patients treated with immune checkpoint inhibitors: a case series of seven patients from a single institution. J Immunother Cancer. 2019 Aug 8;7(1):213. PubMed PMID: 31395100
  • Wilky BA. Immune checkpoint inhibitors: The linchpins of modern immunotherapy. Immunol Rev. 2019 Jul;290(1):6-23. PubMed PMID: 31355494
  • Hall F, Villalobos V, Wilky B. Future directions in soft tissue sarcoma treatment. Curr Probl Cancer. 2019 Aug;43(4):300-307. PubMed PMID: 31229264
  • Wilky BA, Trucco MM, Subhawong TK, Florou V, Park W, Kwon D, Wieder ED, Kolonias D, Rosenberg AE, Kerr DA, Sfakianaki E, Foley M, Merchan JR, Komanduri KV, Trent JC. Axitinib plus pembrolizumab in patients with advanced sarcomas including alveolar soft-part sarcoma: a single-centre, single-arm, phase 2 trial. Lancet Oncol. 2019 Jun;20(6):837-848. PubMed PMID: 31078463
  • Trucco MM, Meyer CF, Thornton KA, Shah P, Chen AR, Wilky BA, Carrera-Haro MA, Boyer LC, Ferreira MF, Shafique U, Powell JD, Loeb DM. A phase II study of temsirolimus and liposomal doxorubicin for patients with recurrent and refractory bone and soft tissue sarcomas. Clin Sarcoma Res. 2018;8:21. PubMed PMID: 30410720
  • Khazeni K, LaBove H, Wilky B, Rosenberg AE, Paulus E, Chim H, Pearson JM, Yakoub D. Myoepithelial carcinoma or epithelioid sarcoma - A rare diagnosis with poor prognosis. A case report and review of literature. Int J Surg Case Rep. 2018;49:239-243. PubMed PMID: 30053614
  • Espejo AP, Ramdial JL, Wilky BA, Kerr DA, Trent JC. A nonrandom association of sarcoidosis in patients with gastrointestinal stromal tumor and other sarcomas. Rare Tumors. 2018;10:2036361318787626. PubMed PMID: 30038741
  • Ramey SJ, Yechieli R, Zhao W, Kodiyan J, Asher D, Chinea FM, Patel V, Reis IM, Wang L, Wilky BA, Subhawong T, Trent JC 2nd. Limb-sparing surgery plus radiotherapy results in superior survival: an analysis of patients with high-grade, extremity soft-tissue sarcoma from the NCDB and SEER. Cancer Med. 2018 Sep;7(9):4228-4239. PubMed PMID: 30030882
  • Ezuddin NS, Pretell-Mazzini J, Yechieli RL, Kerr DA, Wilky BA, Subhawong TK. Local recurrence of soft-tissue sarcoma: issues in imaging surveillance strategy. Skeletal Radiol. 2018 Dec;47(12):1595-1606. PubMed PMID: 29785452
  • Sebio A, Wilky BA, Keedy VL, Jones RL. The current landscape of early drug development for patients with sarcoma in the immunotherapy era. Future Oncol. 2018 May;14(12):1197-1211. PubMed PMID: 29699407
  • Alavi SN, Florou V, Tinoco G, Trent JC, Wilky BA. A precision medicine approach in sarcoma: identification of patients who may benefit from early use of pazopanib. Discov Med. 2018 Mar;25(137):131-144. PubMed PMID: 29641974
  • Florou V, Wilky BA. Current and Future Directions for Angiosarcoma Therapy. Curr Treat Options Oncol. 2018 Mar 8;19(3):14. PubMed PMID: 29520447
  • Upadhyaya SA, McGee RB, Wilky BA, Broniscer A. Malignant progression of a peripheral nerve sheath tumor in the setting of rhabdoid tumor predisposition syndrome. Pediatr Blood Cancer. 2018 Jul;65(7):e27030. PubMed PMID: 29512865
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Professional Memberships

  • American Society of Clinical Oncology, Member

Practice Locations

UCH - Cancer Center
1665 Aurora Ct
Aurora, CO 80045
720-848-0300

University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

Diane O'Connor Thompson Breast Center - Anschutz
1635 Aurora Ct
3rd Floor
Aurora, CO 80045
720-848-1030

UCH - Anschutz Inpatient Pavilion
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

Hospital Affiliation
  • University of Colorado Hospital
Center Affiliations

Specialty Information

Specialties
  • Medical Oncology, Board Certification (2011)
Conditions & Treatments
  • Cancers - Sarcoma
  • Cancers
  • Cancers - Bone Cancer
  • Cancers - Chemotherapy
Clinical Interests
I take care of patients with all kinds of bone and soft tissue tumors and cancers, including sarcomas, desmoid tumors, GIST, and PVNS (tenosynovial giant cell tumor). I an an expert not only in standard chemotherapy treatments, but also am active in clinical trials including immunotherapy, and personalized/precision medicine.

Care Philosophy
I believe that medicine, especially cancer medicine, is best practiced as a partnership between doctors, researchers, and patients. Decisions are always best made as a team effort, taking into account every aspect of a patient's unique situation!

Personal Interests
I have recently moved from Miami, Florida to Denver and had to change my hobbies a bit! My husband and I love fishing and boating, and now are getting into exploring the incredible outdoor activities, including hiking, off-roading in our Jeep, learning to ski, and just being outside with our dog!

Volunteer Activities
I am active with several patient-initiated foundations as an advisory board member, helping to empower patients, families and advocates to advance research to find a cure for sarcomas.

Public Speaking
Yes
I enjoy speaking to patients, families, and physicians in the community to raise awareness of sarcomas and to provide updates on new research including immunotherapy.

General Information

Medical Schools:
  • MD, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School (2006)
Undergraduate Schools:
  • BS, Bates College (ME) (2001)
Internships:
  • Johns Hopkins University School of Medicine Program (2007)
Residency Programs:
  • Johns Hopkins University School of Medicine Program, Internal Medicine (2009)
Fellowships:
  • Johns Hopkins University School of Medicine Program, Medical Oncology (2013)
Download CV
Languages: English
Department: Medicine-Medical Oncology
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