Paula Hoffman, PhD
Professor, Pharmacology

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Department: Pharmacology

Publications

  • Tanabe J, Neff S, Sutton B, Ellis S, Patten L, Brown MS, Hoffman PL, Tabakoff B, Burnham EL. Effects of acetate on cerebral blood flow, systemic inflammation, and behavior in alcohol use disorder. Alcohol Clin Exp Res. 2021 May;45(5):922-933. PubMed PMID: 33682145
  • Saba LM, Hoffman PL, Homanics GE, Mahaffey S, Daulatabad SV, Janga SC, Tabakoff B. A long non-coding RNA (Lrap) modulates brain gene expression and levels of alcohol consumption in rats. Genes Brain Behav. 2021 Feb;20(2):e12698. PubMed PMID: 32893479
  • Hitzemann R, Bergeson SE, Berman AE, Bubier JA, Chesler EJ, Finn DA, Hein M, Hoffman P, Holmes A, Kisby BR, Lockwood D, Lodowski KH, McManus M, Owen JA, Ozburn AR, Panthagani P, Ponomarev I, Saba L, Tabakoff B, Walchale A, Williams RW, Phillips TJ. Sex Differences in the Brain Transcriptome Related to Alcohol Effects and Alcohol Use Disorder. Biol Psychiatry. 2021 May 1. [Epub ahead of print] PubMed PMID: 34274109
  • Tabakoff B, Hoffman PL. Controlling the "Opioid Epidemic": A Novel Chemical Entity (NCE) to Reduce or Supplant Opiate Use for Chronic Pain. J Psychiatr Brain Sci. 2020;5. PubMed PMID: 33117893
  • Saba LM, Hoffman PL, Homanics GE, Mahaffey S, Daulatabad SV, Janga SC, Tabakoff B. A long non-coding RNA (Lrap) modulates brain gene expression and levels of alcohol consumption in rats. Genes Brain Behav. 2020 Sep 6;:e12698. [Epub ahead of print] PubMed PMID: 32893479
  • Alcoholic-Hepatitis, Links to Brain and Microbiome: Mechanisms, Clinical and Experimental Research. Neuman MG, Seitz HK, French SW, Malnick S, Tsukamoto H, Cohen LB, Hoffman P, Tabakoff B, Fasullo M, Nagy LE, Tuma PL, Schnabl B, Mueller S, Groebner JL, Barbara FA, Yue J, Nikko A, Alejandro M, Brittany T, Edward V, Harrall K, Saba L, Mihai O. Biomedicines. 2020 Mar 18;8(3):63. doi: 10.3390/biomedicines8030063. PMID: 32197424
  • Tanabe J, Yamamoto DJ, Sutton B, Brown MS, Hoffman PL, Burnham EL, Glueck DH, Tabakoff B. Effects of Alcohol and Acetate on Cerebral Blood Flow: A Pilot Study. Alcohol Clin Exp Res. 2019 Oct;43(10):2070-2078. PubMed PMID: 31386214
  • Tabakoff B, Smith H, Vanderlinden LA, Hoffman PL, Saba LM. Networking in Biology: The Hybrid Rat Diversity Panel. Methods Mol Biol. 2019;2018:213-231. PubMed PMID: 31228159
  • Rudra P, Shi WJ, Russell P, Vestal B, Tabakoff B, Hoffman P, Kechris K, Saba L. Predictive modeling of miRNA-mediated predisposition to alcohol-related phenotypes in mouse. BMC Genomics. 2018 Aug 29;19(1):639. PubMed PMID: 30157779
  • Lusk R, Saba LM, Vanderlinden LA, Zidek V, Silhavy J, Pravenec M, Hoffman PL, Tabakoff B. Unsupervised, Statistically Based Systems Biology Approach for Unraveling the Genetics of Complex Traits: A Demonstration with Ethanol Metabolism. Alcohol Clin Exp Res. 2018 Jul;42(7):1177-1191. PubMed PMID: 29689131
  • Hoffman PL, Saba LM, Vanderlinden LA, Tabakoff B. Voluntary exposure to a toxin: the genetic influence on ethanol consumption. Mamm Genome. 2018 Feb;29(1-2):128-140. PubMed PMID: 29196862
  • Saba L, Hoffman P, Tabakoff B. Using Baseline Transcriptional Connectomes in Rat to Identify Genetic Pathways Associated with Predisposition to Complex Traits. Methods Mol Biol. 2017;1488:299-317. PubMed PMID: 27933531
  • Hoffman PL, Saba LM, Vanderlinden LA, Tabakoff B. Voluntary exposure to a toxin: the genetic influence on ethanol consumption. Mamm Genome. 2017 Dec 1. [Epub ahead of print] PubMed PMID: 29196862
  • Borghese CM, Herman M, Snell LD, Lawrence KJ, Lee HY, Backos DS, Vanderlinden LA, Harris RA, Roberto M, Hoffman PL, Tabakoff B. Novel Molecule Exhibiting Selective Affinity for GABA(A) Receptor Subtypes. Sci Rep. 2017 Jul 24;7(1):6230. PubMed PMID: 28740086
  • Saba L, Hoffman P, Tabakoff B. Using Baseline Transcriptional Connectomes in Rat to Identify Genetic Pathways Associated with Predisposition to Complex Traits. Methods Mol Biol. 2017;1488:299-317. PubMed PMID: 27933531
  • Harrall KK, Kechris KJ, Tabakoff B, Hoffman PL, Hines LM, Tsukamoto H, Pravenec M, Printz M, Saba LM. Uncovering the liver's role in immunity through RNA co-expression networks. Mamm Genome. 2016 Oct;27(9-10):469-84. PubMed PMID: 27401171
  • Effects of acetate on cerebral blood flow, systemic inflammation, and behavior in alcohol use disorder Jody Tanabe, M.D.a,c, Sarah Neff, B.S.b, Brianne Sutton, Ph.D.c, Sam Ellis, Pharm D.e, Luke Patten, MS.f, Mark S. Brown, Ph.D.a, Paula L. Hoffman, Ph.D.d, Boris Tabakoff, Ph.D.e, Ellen L. Burnham, M.D.b
  • Mahaffey, J, Mahaffey S, Vanderlinden LA, Saba,LM, Hoffman, PL, Pravenec, M, Tabakoff,B A Novel circRNA Highlights a Path to Cardiac Hypertrophy in Spontaneously Hypertensive Rats. Scientific Reports
  • Ryan Lusk, Paula L. Hoffman, Spencer Mahaffey, Michal Pravenec, Boris Tabakoff, Laura M. Saba Beyond genes: Inclusion of alternative splicing and alternative polyadenylation to assess the genetic architecture of predisposition to voluntary alcohol consumption in brain of the HXB/BXH recombinant inbred rat panel . Frontiers in Genetics
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General Information

Department: Pharmacology
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13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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