Faculty Profile | School of Medicine | University of Colorado Denver

Hård Af Segerstad EM, Mramba LK, Liu X, Uusitalo U, Yang J, Norris J, Virtanen SM, Liu E, Kurppa K, Koletzko S, Ziegler AG, Toppari J, Rewers M, Akolkar B, Krischer JP, Aronsson CA, Agardh D. Associations of dietary patterns between age 9 and 24 months with risk of celiac disease autoimmunity and celiac disease among children at increased risk. Am J Clin Nutr. 2023 Dec;118(6):1099-1105. PubMed PMID: 38044022

Lin J, Moradi E, Salenius K, Lehtipuro S, Häkkinen T, Laiho JE, Oikarinen S, Randelin S, Parikh HM, Krischer JP, Toppari J, Lernmark Å, Petrosino JF, Ajami NJ, She JX, Hagopian WA, Rewers MJ, Lloyd RE, Rautajoki KJ, Hyöty H, Nykter M. Distinct transcriptomic profiles in children prior to the appearance of type 1 diabetes-linked islet autoantibodies and following enterovirus infection. Nat Commun. 2023 Nov 22;14(1):7630. PubMed PMID: 37993433

Tisza M, Lloyd R, Hoffman K, Smith D, Rewers M, Cregeen SJ, Petrosino JF. Phage-bacteria dynamics during the first years of life revealed by trans-kingdom marker gene analysis. bioRxiv. 2023 Sep 29. PubMed PMID: 37808738

Sarkar S, Elliott EC, Henry HR, Ludovico ID, Melchior JT, Frazer-Abel A, Webb-Robertson BJ, Davidson WS, Holers VM, Rewers MJ, Metz TO, Nakayasu ES. Systematic review of type 1 diabetes biomarkers reveals regulation in circulating proteins related to complement, lipid metabolism, and immune response. Clin Proteomics. 2023 Sep 21;20(1):38. PubMed PMID: 37735622

Simmons KMW, Frohnert BI, O'Donnell HK, Bautista K, Geno Rasmussen C, Gerard Gonzalez A, Steck AK, Rewers MJ. Historical Insights and Current Perspectives on the Diagnosis and Management of Presymptomatic Type 1 Diabetes. Diabetes Technol Ther. 2023 Nov;25(11):790-799. PubMed PMID: 37695674

Wenzlau JM, Gu Y, Michels A, Rewers M, Haskins K, Yu L. Identification of Autoantibodies to a Hybrid Insulin Peptide in Type 1 Diabetes. Diagnostics (Basel). 2023 Sep 4;13(17). PubMed PMID: 37685398

O'Donnell HK, Rasmussen CG, Dong F, Simmons KM, Steck AK, Frohnert BI, Bautista K, Rewers MJ, Baxter J. Anxiety and Risk Perception in Parents of Children Identified by Population Screening as High Risk for Type 1 Diabetes. Diabetes Care. 2023 Dec 1;46(12):2155-2161. PubMed PMID: 37673098

Onengut-Gumuscu S, Webb-Robertson BM, Sarkar S, Manichaikul A, Hu X, Frazer-Abel A, Holers VM, Rewers MJ, Rich SS. Genetic variants in the complement system and their potential link in the aetiology of type 1 diabetes. Diabetes Metab Res Rev. 2023 Aug 30;:e3716. [Epub ahead of print] PubMed PMID: 37649398

Aronsson CA, Tamura R, Vehik K, Uusitalo U, Yang J, Haller MJ, Toppari J, Hagopian W, McIndoe RA, Rewers MJ, Ziegler AG, Akolkar B, Krischer JP, Norris JM, Virtanen SM, Larsson HE. Dietary Intake and Body Mass Index Influence the Risk of Islet Autoimmunity in Genetically At-Risk Children: A Mediation Analysis Using the TEDDY Cohort. Pediatr Diabetes. 2023;2023. PubMed PMID: 37614409

Lönnrot M, Lynch KF, Rewers M, Lernmark Å, Vehik K, Akolkar B, Hagopian W, Krischer J, McIndoe RA, Toppari J, Ziegler AG, Petrosino JF, Lloyd R, Hyöty H. Gastrointestinal Infections Modulate the Risk for Insulin Autoantibodies as the First-Appearing Autoantibody in the TEDDY Study. Diabetes Care. 2023 Nov 1;46(11):1908-1915. PubMed PMID: 37607456

Uusitalo U, Mramba LK, Aronsson CA, Vehik K, Yang J, Hummel S, Lernmark Å, Rewers M, Hagopian W, McIndoe R, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Virtanen SM, Norris JM. HLA Genotype and Probiotics Modify the Association Between Timing of Solid Food Introduction and Islet Autoimmunity in the TEDDY Study. Diabetes Care. 2023 Oct 1;46(10):1839-1847. PubMed PMID: 37579501

Liebhoff AM, Venkataraman T, Morgenlander WR, Na M, Kula T, Waugh K, Morrison C, Rewers M, Longman R, Round J, Elledge S, Ruczinski I, Langmead B, Larman HB. Efficient encoding of large antigenic spaces by epitope prioritization with Dolphyn. bioRxiv. 2023 Jul 31. PubMed PMID: 37577562

Krischer JP, Lernmark Å, Hagopian WA, Rewers MJ, McIndoe R, Toppari J, Ziegler AG, Akolkar B. SARS-CoV-2 - No Increased Islet Autoimmunity or Type 1 Diabetes in Teens. N Engl J Med. 2023 Aug 3;389(5):474-475. PubMed PMID: 37530831

Webb-Robertson BM, Nakayasu ES, Dong F, Waugh KC, Flores J, Bramer LM, Schepmoes A, Gao Y, Fillmore T, Onengut-Gumuscu S, Frazer-Abel A, Rich SS, Holers VM, Metz TO, Rewers MJ. Decrease in multiple complement protein levels is associated with the development of islet autoimmunity and type 1 diabetes. medRxiv. 2023 Jul 16. PubMed PMID: 37502972

Frost HM, Geno Rasmussen C, Shorrosh H, Pyle L, Bautista K, Frohnert BI, Stahl M, Simmons K, Steck AK, Jia X, Yu L, Rewers M. Prevalence of SARS-CoV-2 Antibodies Among Healthy Children From Colorado From 2020 to 2021: A Brief Report. J Prim Care Community Health. 2023 Jan-Dec;14:21501319231189147. PubMed PMID: 37501515

Nakayasu ES, Bramer LM, Ansong C, Schepmoes AA, Fillmore TL, Gritsenko MA, Clauss TR, Gao Y, Piehowski PD, Stanfill BA, Engel DW, Orton DJ, Moore RJ, Qian WJ, Sechi S, Frohnert BI, Toppari J, Ziegler AG, Lernmark Å, Hagopian W, Akolkar B, Smith RD, Rewers MJ, Webb-Robertson BM, Metz TO. Plasma protein biomarkers predict the development of persistent autoantibodies and type 1 diabetes 6 months prior to the onset of autoimmunity. Cell Rep Med. 2023 Jul 18;4(7):101093. PubMed PMID: 37390828

Cai LY, Tanase C, Anderson AW, Patel NJ, Lee CA, Jones RS, LeStourgeon LM, Mahon A, Taki I, Juvera J, Pruthi S, Gwal K, Ozturk A, Kang H, Rewers A, Rewers MJ, Alonso GT, Glaser N, Ghetti S, Jaser SS, Landman BA, Jordan LC. Exploratory Multisite MR Spectroscopic Imaging Shows White Matter Neuroaxonal Loss Associated with Complications of Type 1 Diabetes in Children. AJNR Am J Neuroradiol. 2023 Jul;44(7):820-827. PubMed PMID: 37263786

Mameli C, Triolo TM, Chiarelli F, Rewers M, Zuccotti G, Simmons KM. Lessons and gaps in the prediction and prevention of type 1 diabetes. Pharmacol Res. 2023 Jul;193:106792. PubMed PMID: 37201589

Corrado MM, Jia X, Geno Rasmussen C, Pyle L, Yu L, Liu E, Stahl M, Rewers MJ. Previous SARS-CoV-2 Infection Is Not Associated With Increased Celiac Disease Autoimmunity in Children and Adolescents. Am J Gastroenterol. 2023 Sep 1;118(9):1698-1700. PubMed PMID: 37159249

Lernmark Å, Akolkar B, Hagopian W, Krischer J, McIndoe R, Rewers M, Toppari J, Vehik K, Ziegler AG. Possible heterogeneity of initial pancreatic islet beta-cell autoimmunity heralding type 1 diabetes. J Intern Med. 2023 Aug;294(2):145-158. PubMed PMID: 37143363

Liu X, Johnson SB, Lynch KF, Cordan K, Pate R, Butterworth MD, Lernmark Å, Hagopian WA, Rewers MJ, McIndoe RA, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Yang J. Physical Activity and the Development of Islet Autoimmunity and Type 1 Diabetes in 5- to 15-Year-Old Children Followed in the TEDDY Study. Diabetes Care. 2023 Jul 1;46(7):1409-1416. PubMed PMID: 37141102

Buckner T, Johnson RK, Vanderlinden LA, Carry PM, Romero A, Onengut-Gumuscu S, Chen WM, Kim S, Fiehn O, Frohnert BI, Crume T, Perng W, Kechris K, Rewers M, Norris JM. Genome-wide analysis of oxylipins and oxylipin profiles in a pediatric population. Front Nutr. 2023;10:1040993. PubMed PMID: 37057071

Elhassan S, Dong F, Buckner T, Johnson RK, Seifert JA, Carry PM, Vanderlinden L, Waugh K, Rewers M, Norris JM. Investigating iron intake in risk of progression from islet autoimmunity to type 1 diabetes: The diabetes autoimmunity study in the young. Front Immunol. 2023;14:1124370. PubMed PMID: 37056761

Jia X, Dong F, Pyle L, Michels AW, Yu L, Rewers M. Similar Time Course of Humoral Response to SARS-CoV-2 mRNA Vaccines in People With and Without Type 1 Diabetes. Diabetes Technol Ther. 2023 Jul;25(7):492-496. PubMed PMID: 36989496

Thorsen SU, Liu X, Kataria Y, Mandrup-Poulsen T, Kaur S, Uusitalo U, Virtanen SM, Norris JM, Rewers M, Hagopian W, Yang J, She JX, Akolkar B, Rich S, Aronsson CA, Lernmark Å, Ziegler AG, Toppari J, Krischer J, Parikh HM, Ellervik C, Svensson J. Interaction Between Dietary Iron Intake and Genetically Determined Iron Overload: Risk of Islet Autoimmunity and Progression to Type 1 Diabetes in the TEDDY Study. Diabetes Care. 2023 May 1;46(5):1014-1018. PubMed PMID: 36867433

Sarkar S, Elliott EC, Henry HR, Ludovico ID, Melchior JT, Frazer-Abel A, Webb-Robertson BJ, Davidson WS, Holers VM, Rewers MJ, Metz TO, Nakayasu ES. Systematic review of type 1 diabetes biomarkers reveals regulation in circulating proteins related to complement, lipid metabolism, and immune response. medRxiv. 2023 Feb 22. PubMed PMID: 36865103

Buckner T, Johnson RK, Vanderlinden LA, Carry PM, Romero A, Onengut-Gumuscu S, Chen WM, Fiehn O, Frohnert BI, Crume T, Perng W, Kechris K, Rewers M, Norris JM. An Oxylipin-Related Nutrient Pattern and Risk of Type 1 Diabetes in the Diabetes Autoimmunity Study in the Young (DAISY). Nutrients. 2023 Feb 14;15(4). PubMed PMID: 36839302

Rewers M, Ziegler AG. SARS-CoV-2 Infections and Presymptomatic Type 1 Diabetes Autoimmunity in Children and Adolescents-Reply. JAMA. 2023 Feb 14;329(6):512-513. PubMed PMID: 36786793

Mehta P, Li Q, Stahl M, Uusitalo U, Lindfors K, Butterworth MD, Kurppa K, Virtanen S, Koletzko S, Aronsson C, Hagopian WA, Rewers MJ, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Agardh D, Liu E. Gluten-free diet adherence in children with screening-detected celiac disease using a prospective birth cohort study. PLoS One. 2023;18(2):e0275123. PubMed PMID: 36730234

Ghalwash M, Anand V, Lou O, Martin F, Rewers M, Ziegler AG, Toppari J, Hagopian WA, Veijola R. Islet autoantibody screening in at-risk adolescents to predict type 1 diabetes until young adulthood: a prospective cohort study. Lancet Child Adolesc Health. 2023 Apr;7(4):261-268. PubMed PMID: 36681087

Stahl M, Li Q, Lynch K, Koletzko S, Mehta P, Gragert L, Norris JM, Andrén Aronsson C, Lindfors K, Kurppa K, Ilonen J, Krischer J, Alkolkar B, Ziegler AG, Toppari J, Rewers MJ, Agardh D, Hagopian W, Liu E. Incidence of Pediatric Celiac Disease Varies by Region. Am J Gastroenterol. 2023 Mar 1;118(3):539-545. PubMed PMID: 36219178

Frohnert BI, Ghalwash M, Li Y, Ng K, Dunne JL, Lundgren M, Hagopian W, Lou O, Winkler C, Toppari J, Veijola R, Anand V. Refining the Definition of Stage 1 Type 1 Diabetes: An Ontology-Driven Analysis of the Heterogeneity of Multiple Islet Autoimmunity. Diabetes Care. 2023 Oct 1;46(10):1753-1761. PubMed PMID: 36862942

Trainor JL, Glaser NS, Tzimenatos L, Stoner MJ, Brown KM, McManemy JK, Schunk JE, Quayle KS, Nigrovic LE, Rewers A, Myers SR, Bennett JE, Kwok MY, Olsen CS, Casper TC, Ghetti S, Kuppermann N. Clinical and Laboratory Predictors of Dehydration Severity in Children With Diabetic Ketoacidosis. Ann Emerg Med. 2023 Aug;82(2):167-178. PubMed PMID: 37024382

Jacobsen LM et al. Heterogeneity of DKA Incidence and Age-Specific Clinical Characteristics in Children Diagnosed With Type 1 Diabetes in the TEDDY Study. Diabetes Care. 2022 Jan 12. PubMed PMID: 35043162

Steck AK, Dong F, Geno Rasmussen C, Bautista K, Sepulveda F, Baxter J, Yu L, Frohnert BI, Rewers MJ. CGM Metrics Predict Imminent Progression to Type 1 Diabetes: Autoimmunity Screening for Kids (ASK) Study. Diabetes Care. 2022 Feb 1;45(2):365-371. PubMed PMID: 34880069

Yashpal S, Liese AD, Boucher BA, Wagenknecht LE, Haffner SM, Johnston LW, Bazinet RP, Rewers M, Rotter JI, Watkins SM, Hanley AJ. Metabolomic profiling of the Dietary Approaches to Stop Hypertension diet provides novel insights for the nutritional epidemiology of type 2 diabetes mellitus. Br J Nutr. 2022 Aug 14;128(3):487-497. PubMed PMID: 34511138

Steck AK, Dong F, Geno Rasmussen C, Bautista K, Sepulveda F, Baxter J, Yu L, Frohnert BI, Rewers MJ, Rewers M, Barbour A, Bautista K, Baxter J, Felipe-Morales D, Dong F, Dormond-Brooks P, Driscoll K, Frohnert B, Rasmussen CG, Gesualdo P, Hoffman M, Karban R, Sepulveda F, Shorrosh H, Simmons K, Steck A, Taki I, Waugh K, Yu L, Liu E, Gallant M, McQueen RB, Norris JM. CGM Metrics Predict Imminent Progression to Type 1 Diabetes: Autoimmunity Screening for Kids (ASK) Study. Diabetes Care. 2022 Feb 1;45(2):365-371. PubMed PMID: 34880069

Monaco DR, Kottapalli SV, Breitwieser FP, Anderson DE, Wijaya L, Tan K, Chia WN, Kammers K, Caturegli P, Waugh K, Roederer M, Petri M, Goldman DW, Rewers M, Wang LF, Larman HB. Deconvoluting virome-wide antibody epitope reactivity profiles. EBioMedicine. 2022 Jan;75:103747. PubMed PMID: 34922324

Malik FS, Sauder KA, Isom S, Reboussin BA, Dabelea D, Lawrence JM, Roberts A, Mayer-Davis EJ, Marcovina S, Dolan L, Igudesman D, Pihoker C, Lawrence JM, Hung P, Koebnick C, Li X, Lustigova E, Reynolds K, Pettitt DJ, Mayer-Davis EJ, Mottl A, Thomas J, Jackson M, Knight L, Liese AD, Turley C, Bowlby D, Amrhein J, Apperson E, Nelson B, Dabelea D, Bellatorre A, Crume T, Hamman RF, Sauder KA, Shapiro A, Testaverde L, Klingensmith GJ, Maahs D, Rewers MJ, Wadwa P, Daniels S, Kahn MG, Wilkening G, Bloch CA, Powell J, Love-Osborne K, Hu DC, Dolan LM, Shah AS, Standiford DA, Urbina EM, Pihoker C, Hirsch I, Kim G, Malik FA, Merjaneh L, Roberts A, Taplin C, Yi-Frazier J, Beauregard N, Franklin C, Gangan C, Kearns S, Klingsheim M, Loots B, Pascual M, Greenbaum C, Imperatore G, Saydah SH, Linder B, Marcovina SM, Chait A, Clouet-Foraison N, Harting J, Strylewicz G, D'Agostino R, Jensen ET, Wagenknecht LE, Bell RA, Casanova R, Divers J, Goldstein MT, Henkin L, Isom S, Lenoir K, Pierce J, Reboussin B, Rigdon J, South AM, Stafford J, Suerken C, Wells B, Williams C. Trends in Glycemic Control Among Youth and Young Adults With Diabetes: The SEARCH for Diabetes in Youth Study. Diabetes Care. 2022 Feb 1;45(2):285-294. PubMed PMID: 34995346

Jacobsen LM, Vehik K, Veijola R, Warncke K, Toppari J, Steck AK, Gesualdo P, Akolkar B, Lundgren M, Hagopian WA, She JX, Rewers M, Ziegler AG, Krischer JP, Larsson HE, Haller MJ. Heterogeneity of DKA Incidence and Age-Specific Clinical Characteristics in Children Diagnosed With Type 1 Diabetes in the TEDDY Study. Diabetes Care. 2022 Mar 1;45(3):624-633. PubMed PMID: 35043162

Snell-Bergeon J, Waugh K, Dong F, Steck A, Norris J, Rewers M. Physical activity and progression to type 1 diabetes in children and youth with islet autoimmunity: The diabetes autoimmunity study in the young. Pediatr Diabetes. 2022 Jun;23(4):462-468. PubMed PMID: 35142009

Ferrat LA, Vehik K, Sharp SA, Lernmark Å, Rewers MJ, She JX, Ziegler AG, Toppari J, Akolkar B, Krischer JP, Weedon MN, Oram RA, Hagopian WA. Author Correction: A combined risk score enhances prediction of type 1 diabetes among susceptible children. Nat Med. 2022 Mar;28(3):599. PubMed PMID: 35165454

He L, Jia X, Rasmussen CG, Waugh K, Miao D, Dong F, Frohnert B, Steck AK, Simmons KM, Rewers M, Yu L. High-Throughput Multiplex Electrochemiluminescence Assay Applicable to General Population Screening for Type 1 Diabetes and Celiac Disease. Diabetes Technol Ther. 2022 Jul;24(7):502-509. PubMed PMID: 35238620

Törn C, Liu X, Onengut-Gumuscu S, Counts KM, Moreno JL, Remedios CL, Chen WM, LeFaive J, Butterworth MD, Akolkar B, Krischer JP, Lernmark Å, Rewers M, She JX, Toppari J, Ziegler AG, Ratan A, Smith AV, Hagopian WA, Rich SS, Parikh HM. Telomere length is not a main factor for the development of islet autoimmunity and type 1 diabetes in the TEDDY study. Sci Rep. 2022 Mar 16;12(1):4516. PubMed PMID: 35296692

Sims EK, Besser REJ, Dayan C, Geno Rasmussen C, Greenbaum C, Griffin KJ, Hagopian W, Knip M, Long AE, Martin F, Mathieu C, Rewers M, Steck AK, Wentworth JM, Rich SS, Kordonouri O, Ziegler AG, Herold KC. Screening for Type 1 Diabetes in the General Population: A Status Report and Perspective. Diabetes. 2022 Apr 1;71(4):610-623. PubMed PMID: 35316839

Webb-Robertson BM, Nakayasu ES, Frohnert BI, Bramer LM, Akers SM, Norris JM, Vehik K, Ziegler AG, Metz TO, Rich SS, Rewers MJ. Integration of Infant Metabolite, Genetic, and Islet Autoimmunity Signatures to Predict Type 1 Diabetes by Age 6 Years. J Clin Endocrinol Metab. 2022 Jul 14;107(8):2329-2338. PubMed PMID: 35468213

Auchtung TA, Stewart CJ, Smith DP, Triplett EW, Agardh D, Hagopian WA, Ziegler AG, Rewers MJ, She JX, Toppari J, Lernmark Å, Akolkar B, Krischer JP, Vehik K, Auchtung JM, Ajami NJ, Petrosino JF. Temporal changes in gastrointestinal fungi and the risk of autoimmunity during early childhood: the TEDDY study. Nat Commun. 2022 Jun 7;13(1):3151. PubMed PMID: 35672407

Carry PM, Waugh K, Vanderlinden LA, Johnson RK, Buckner T, Rewers M, Steck AK, Yang I, Fingerlin TE, Kechris K, Norris JM. Changes in the Coexpression of Innate Immunity Genes During Persistent Islet Autoimmunity Are Associated With Progression of Islet Autoimmunity: Diabetes Autoimmunity Study in the Young (DAISY). Diabetes. 2022 Sep 1;71(9):2048-2057. PubMed PMID: 35724268

Chiarelli F, Rewers M, Phillip M. Screening of Islet Autoantibodies for Children in the General Population: A Position Statement Endorsed by the European Society for Paediatric Endocrinology. Horm Res Paediatr. 2022;95(4):393-396. PubMed PMID: 35780775

Ghalwash M, Dunne JL, Lundgren M, Rewers M, Ziegler AG, Anand V, Toppari J, Veijola R, Hagopian W. Two-age islet-autoantibody screening for childhood type 1 diabetes: a prospective cohort study. Lancet Diabetes Endocrinol. 2022 Aug;10(8):589-596. PubMed PMID: 35803296

Jia X, He L, Miao D, Zhang C, Rewers M, Yu L. A High-throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19. J Vis Exp. 2022 Jul 5;(185). PubMed PMID: 35876559

Rewers M, Bonifacio E, Ewald D, Geno Rasmussen C, Jia X, Pyle L, Ziegler AG. SARS-CoV-2 Infections and Presymptomatic Type 1 Diabetes Autoimmunity in Children and Adolescents From Colorado, USA, and Bavaria, Germany. JAMA. 2022 Sep 27;328(12):1252-1255. PubMed PMID: 35930271

Mitchell AM, Baschal EE, McDaniel KA, Simmons KM, Pyle L, Waugh K, Steck AK, Yu L, Gottlieb PA, Rewers MJ, Nakayama M, Michels AW. Temporal development of T cell receptor repertoires during childhood in health and disease. JCI Insight. 2022 Sep 22;7(18). PubMed PMID: 35998036

Salami F, Tamura R, You L, Lernmark Å, Larsson HE, Lundgren M, Krischer J, Ziegler AG, Toppari J, Veijola R, Rewers M, Haller MJ, Hagopian W, Akolkar B, Törn C. HbA1c as a time predictive biomarker for an additional islet autoantibody and type 1 diabetes in seroconverted TEDDY children. Pediatr Diabetes. 2022 Dec;23(8):1586-1593. PubMed PMID: 36082496

Krischer JP, Liu X, Lernmark Å, Hagopian WA, Rewers MJ, She JX, Toppari J, Ziegler AG, Akolkar B. Predictors of the Initiation of Islet Autoimmunity and Progression to Multiple Autoantibodies and Clinical Diabetes: The TEDDY Study. Diabetes Care. 2022 Oct 1;45(10):2271-2281. PubMed PMID: 36150053

Vehik K, Boulware D, Killian M, Rewers M, McIndoe R, Toppari J, Lernmark Å, Akolkar B, Ziegler AG, Rodriguez H, Schatz DA, Krischer JP, Hagopian W. Rising Hemoglobin A1c in the Nondiabetic Range Predicts Progression of Type 1 Diabetes As Well As Oral Glucose Tolerance Tests. Diabetes Care. 2022 Oct 1;45(10):2342-2349. PubMed PMID: 36150054

Tran PMH, Dong F, Kim E, Richardson KP, Tran LKH, Waugh K, Hopkins D, Cummings RD, Wang PG, Rewers MJ, She JX, Purohit S. Use of a glycomics array to establish the anti-carbohydrate antibody repertoire in type 1 diabetes. Nat Commun. 2022 Nov 1;13(1):6527. PubMed PMID: 36316364

Hård Af Segerstad EM, Liu X, Uusitalo U, Agardh D, Andrén Aronsson C. Sources of dietary gluten in the first 2 years of life and associations with celiac disease autoimmunity and celiac disease in Swedish genetically predisposed children: The Environmental Determinants of Diabetes in the Young (TEDDY) study. Am J Clin Nutr. 2022 Aug 4;116(2):394-403. PubMed PMID: 35394004

Melin J, Lynch KF, Lundgren M, Aronsson CA, Larsson HE, Johnson SB. Is staff consistency important to parents' satisfaction in a longitudinal study of children at risk for type 1 diabetes: the TEDDY study. BMC Endocr Disord. 2022 Jan 10;22(1):19. PubMed PMID: 35012530

Li Q, Liu X, Yang J, Erlund I, Lernmark Å, Hagopian W, Rewers M, She JX, Toppari J, Ziegler AG, Akolkar B, Krischer JP. Plasma Metabolome and Circulating Vitamins Stratified Onset Age of an Initial Islet Autoantibody and Progression to Type 1 Diabetes: The TEDDY Study. Diabetes. 2021 Jan;70(1):282-292. PubMed PMID: 33106256

Stahl MG, Geno Rasmussen C, Dong F, Waugh K, Norris JM, Baxter J, Yu L, Steck AK, Frohnert BI, Liu E, Rewers MJ. Mass Screening for Celiac Disease: The Autoimmunity Screening for Kids Study. Am J Gastroenterol. 2021 Jan 1;116(1):180-187. PubMed PMID: 32701732

Johnson SB, Lynch KF, Roth R, Lundgren M, Parikh HM, Akolkar B, Hagopian W, Krischer J, Rewers M, She JX, Toppari J, Ziegler AG, Lernmark Å. First-appearing islet autoantibodies for type 1 diabetes in young children: maternal life events during pregnancy and the child's genetic risk. Diabetologia. 2021 Jan 6. [Epub ahead of print] PubMed PMID: 33404683

Tran PM, Purohit S, Kim E, Bin Satter K, Hopkins D, Waugh K, Dong F, Onengut-Gumuscu S, Rich SS, Rewers M, She JX. The 3p21.31 genetic locus promotes progression to type 1 diabetes through the CCR2/CCL2 pathway. J Transl Autoimmun. 2021;4:100127. PubMed PMID: 35005592

Monaco DR, Kottapalli SV, Breitwieser FP, Anderson DE, Wijaya L, Tan K, Chia WN, Kammers K, Caturegli P, Waugh K, Roederer M, Petri M, Goldman DW, Rewers M, Wang LF, Larman HB. Deconvoluting virome-wide antibody epitope reactivity profiles. EBioMedicine. 2021 Dec 15;75:103747. [Epub ahead of print] PubMed PMID: 34922324

Walker-Short E, Buckner T, Vigers T, Carry P, Vanderlinden LA, Dong F, Johnson RK, Yang IV, Kechris K, Rewers M, Norris JM. Epigenome-Wide Association Study of Infant Feeding and DNA Methylation in Infancy and Childhood in a Population at Increased Risk for Type 1 Diabetes. Nutrients. 2021 Nov 13;13(11). PubMed PMID: 34836312

Andrén Aronsson C, Liu X, Norris JM, Uusitalo U, Butterworth MD, Koletzko S, Virtanen SM, Erlund I, Kurppa K, Hagopian WA, Rewers MJ, She JX, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Agardh D. 25(OH)D Levels in Infancy Is Associated With Celiac Disease Autoimmunity in At-Risk Children: A Case-Control Study. Front Nutr. 2021;8:720041. PubMed PMID: 34604278

Yashpal S, Liese AD, Boucher BA, Wagenknecht LE, Haffner SM, Johnston LW, Bazinet RP, Rewers M, Rotter JI, Watkins SM, Hanley AJ. Metabolomic profiling of the Dietary Approaches to Stop Hypertension diet provides novel insights for the nutritional epidemiology of type 2 diabetes mellitus. Br J Nutr. 2021 Sep 13;:1-11. [Epub ahead of print] PubMed PMID: 34511138

Vigers T, Vanderlinden LA, Johnson RK, Carry PM, Yang I, DeFelice BC, Kaizer AM, Pyle L, Rewers M, Fiehn O, Norris JM, Kechris K. A Mediation Approach to Discovering Causal Relationships between the Metabolome and DNA Methylation in Type 1 Diabetes. Metabolites. 2021 Aug 14;11(8). PubMed PMID: 34436483

Jia X, He L, Miao D, Waugh K, Rasmussen CG, Dong F, Steck AK, Rewers M, Yu L. High-affinity ZnT8 Autoantibodies by Electrochemiluminescence Assay Improve Risk Prediction for Type 1 Diabetes. J Clin Endocrinol Metab. 2021 Nov 19;106(12):3455-3463. PubMed PMID: 34343303

Krischer JP, Liu X, Lernmark Å, Hagopian WA, Rewers MJ, She JX, Toppari J, Ziegler AG, Akolkar B. Characteristics of children diagnosed with type 1 diabetes before vs after 6 years of age in the TEDDY cohort study. Diabetologia. 2021 Oct;64(10):2247-2257. PubMed PMID: 34291312

Gu Y, Jia X, Vartak T, Miao D, Dong F, Jerram ST, Rewers M, Ferrara A, Lawrence JM, Yu L, Leslie RD. Improving clinical utility of GAD65 autoantibodies by electrochemiluminescence assay and clinical phenotype when identifying autoimmune adult-onset diabetes. Diabetologia. 2021 Sep;64(9):2052-2060. PubMed PMID: 34272582

Nakayasu ES, Gritsenko M, Piehowski PD, Gao Y, Orton DJ, Schepmoes AA, Fillmore TL, Frohnert BI, Rewers M, Krischer JP, Ansong C, Suchy-Dicey AM, Evans-Molina C, Qian WJ, Webb-Robertson BM, Metz TO. Tutorial: best practices and considerations for mass-spectrometry-based protein biomarker discovery and validation. Nat Protoc. 2021 Aug;16(8):3737-3760. PubMed PMID: 34244696

Anand V, Li Y, Liu B, Ghalwash M, Koski E, Ng K, Dunne JL, Jönsson J, Winkler C, Knip M, Toppari J, Ilonen J, Killian MB, Frohnert BI, Lundgren M, Ziegler AG, Hagopian W, Veijola R, Rewers M. Islet Autoimmunity and HLA Markers of Presymptomatic and Clinical Type 1 Diabetes: Joint Analyses of Prospective Cohort Studies in Finland, Germany, Sweden, and the U.S. Diabetes Care. 2021; 44(10):2269–2276. PubMed PMID: 34162665

Gu Y, Merriman C, Guo Z, Jia X, Wenzlau J, Li H, Li H, Rewers M, Yu L, Fu D. Novel autoantibodies to the ß-cell surface epitopes of ZnT8 in patients progressing to type-1 diabetes. J Autoimmun. 2021 Aug;122:102677. PubMed PMID: 34130115

Robertson CC, Inshaw JRJ, Onengut-Gumuscu S, Chen WM, Santa Cruz DF, Yang H, Cutler AJ, Crouch DJM, Farber E, Bridges SL Jr, Edberg JC, Kimberly RP, Buckner JH, Deloukas P, Divers J, Dabelea D, Lawrence JM, Marcovina S, Shah AS, Greenbaum CJ, Atkinson MA, Gregersen PK, Oksenberg JR, Pociot F, Rewers MJ, Steck AK, Dunger DB, Wicker LS, Concannon P, Todd JA, Rich SS. Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes. Nat Genet. 2021 Jul;53(7):962-971. PubMed PMID: 34127860

Buckner T, Vanderlinden LA, DeFelice BC, Carry PM, Kechris K, Dong F, Fiehn O, Frohnert BI, Clare-Salzler M, Rewers M, Norris JM. The oxylipin profile is associated with development of type 1 diabetes: the Diabetes Autoimmunity Study in the Young (DAISY). Diabetologia. 2021 Aug;64(8):1785-1794. PubMed PMID: 33893822

Carry PM, Vanderlinden LA, Johnson RK, Buckner T, Fiehn O, Steck AK, Kechris K, Yang I, Fingerlin TE, Rewers M, Norris JM. Phospholipid Levels at Seroconversion Are Associated With Resolution of Persistent Islet Autoimmunity: The Diabetes Autoimmunity Study in the Young. Diabetes. 2021 Jul;70(7):1592-1601. PubMed PMID: 33863802

Hummel S, Weiß A, Bonifacio E, Agardh D, Akolkar B, Aronsson CA, Hagopian WA, Koletzko S, Krischer JP, Lernmark Å, Lynch K, Norris JM, Rewers MJ, She JX, Toppari J, Uusitalo U, Vehik K, Virtanen SM, Beyerlein A, Ziegler AG. Associations of breastfeeding with childhood autoimmunity, allergies, and overweight: The Environmental Determinants of Diabetes in the Young (TEDDY) study. Am J Clin Nutr. 2021 Jul 1;114(1):134-142. PubMed PMID: 33831944

Xhonneux LP, Knight O, Lernmark Å, Bonifacio E, Hagopian WA, Rewers MJ, She JX, Toppari J, Parikh H, Smith KGC, Ziegler AG, Akolkar B, Krischer JP, McKinney EF. Transcriptional networks in at-risk individuals identify signatures of type 1 diabetes progression. Sci Transl Med. 2021 Mar 31;13(587). PubMed PMID: 33790023

Johnson RK, Tamura R, Frank N, Uusitalo U, Yang J, Niinistö S, Andrén Aronsson C, Ziegler AG, Hagopian W, Rewers M, Toppari J, Akolkar B, Krischer J, Virtanen SM, Norris JM. Maternal food consumption during late pregnancy and offspring risk of islet autoimmunity and type 1 diabetes. Diabetologia. 2021 Jul;64(7):1604-1612. PubMed PMID: 33783586

Bonifacio E, Weiß A, Winkler C, Hippich M, Rewers MJ, Toppari J, Lernmark Å, She JX, Hagopian WA, Krischer JP, Vehik K, Schatz DA, Akolkar B, Ziegler AG. An Age-Related Exponential Decline in the Risk of Multiple Islet Autoantibody Seroconversion During Childhood. Diabetes Care. 2021 Feb 24. [Epub ahead of print] PubMed PMID: 33627366

Niinistö S, Erlund I, Lee HS, Uusitalo U, Salminen I, Aronsson CA, Parikh HM, Liu X, Hummel S, Toppari J, She JX, Lernmark Å, Ziegler AG, Rewers M, Akolkar B, Krischer JP, Galas D, Das S, Sakhanenko N, Rich SS, Hagopian W, Norris JM, Virtanen SM. Children's erythrocyte fatty acids are associated with the risk of islet autoimmunity. Sci Rep. 2021 Feb 11;11(1):3627. PubMed PMID: 33574451

Jia X, Gesualdo P, Geno Rasmussen C, Alkanani AA, He L, Dong F, Rewers MJ, Michels AW, Yu L. Prevalence of SARS-CoV-2 Antibodies in Children and Adults with Type 1 Diabetes. Diabetes Technol Ther. 2021 Jul;23(7):517-521. PubMed PMID: 33544017

Mitchell AM, Alkanani AA, McDaniel KA, Pyle L, Waugh K, Steck AK, Nakayama M, Yu L, Gottlieb PA, Rewers MJ, Michels AW. T-cell responses to hybrid insulin peptides prior to type 1 diabetes development. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6). PubMed PMID: 33542101

Johnson SB, Lynch KF, Roth R, Lundgren M, Parikh HM, Akolkar B, Hagopian W, Krischer J, Rewers M, She JX, Toppari J, Ziegler AG, Lernmark Å. First-appearing islet autoantibodies for type 1 diabetes in young children: maternal life events during pregnancy and the child's genetic risk. Diabetologia. 2021 Mar;64(3):591-602. PubMed PMID: 33404683

Lawrence JM, Slezak JM, Quesenberry C, Li X, Yu L, Rewers M, Alexander JG, Takhar HS, Sridhar S, Albright A, Rolka DB, Saydah S, Imperatore G, Ferrara A. Incidence and predictors of type 1 diabetes among younger adults aged 20-45 years: The diabetes in young adults (DiYA) study. Diabetes Res Clin Pract. 2021 Jan;171:108624. PubMed PMID: 33338552

Dunne JL, Koralova A, Sutphin J, Bushman JS, Fontanals-Ciera B, Coulter JR, Hutton CT, Rewers MJ, Mansfield C. Parent and Pediatrician Preferences for Type 1 Diabetes Screening in the U.S. Diabetes Care. 2021 Feb;44(2):332-339. PubMed PMID: 33303637

Webb-Robertson BM, Bramer LM, Stanfill BA, Reehl SM, Nakayasu ES, Metz TO, Frohnert BI, Norris JM, Johnson RK, Rich SS, Rewers MJ. Prediction of the development of islet autoantibodies through integration of environmental, genetic, and metabolic markers. J Diabetes. 2021 Feb;13(2):143-153. PubMed PMID: 33124145

Li Q, Liu X, Yang J, Erlund I, Lernmark Å, Hagopian W, Rewers M, She JX, Toppari J, Ziegler AG, Akolkar B, Krischer JP. Plasma Metabolome and Circulating Vitamins Stratified Onset Age of an Initial Islet Autoantibody and Progression to Type 1 Diabetes: The TEDDY Study. Diabetes. 2021 Jan;70(1):282-292. PubMed PMID: 33106256

Steck AK, Liu X, Krischer JP, Haller MJ, Veijola R, Lundgren M, Ahmed S, Akolkar B, Toppari J, Hagopian WA, Rewers MJ, Elding Larsson H. Factors Associated With the Decline of C-Peptide in a Cohort of Young Children Diagnosed With Type 1 Diabetes. J Clin Endocrinol Metab. 2021 Mar 8;106(3):e1380-e1388. PubMed PMID: 33035311

Buckner T, Vanderlinden LA, Johnson RK, DeFelice BC, Carry PM, Seifert J, Waugh K, Dong F, Fiehn O, Clare-Salzler M, Rewers M, Norris JM. Predictors of oxylipins in a healthy pediatric population. Pediatr Res. 2021 May;89(6):1530-1540. PubMed PMID: 32726799

Stahl MG, Geno Rasmussen C, Dong F, Waugh K, Norris JM, Baxter J, Yu L, Steck AK, Frohnert BI, Liu E, Rewers MJ. Mass Screening for Celiac Disease: The Autoimmunity Screening for Kids Study. Am J Gastroenterol. 2021 Jan 1;116(1):180-187. PubMed PMID: 32701732

Ghalwash M, Koski E, Veijola R, Toppari J, Hagopian W, Rewers M, Anand V. Simulating Screening for Risk of Childhood Diabetes: The Collaborative Open Outcomes tooL (COOL). AMIA Annu Symp Proc. 2021;2021:516-525. PubMed PMID: 35308967

Brænne I, Onengut-Gumuscu S, Chen R, Manichaikul AW, Rich SS, Chen WM, Farber CR. Dynamic changes in immune gene co-expression networks predict development of type 1 diabetes. Sci Rep. 2021 Nov 22;11(1):22651. PubMed PMID: 34811390

Lawrence JM, Reynolds K, Saydah SH, Mottl A, Pihoker C, Dabelea D, Dolan L, Henkin L, Liese AD, Isom S, Divers J, Wagenknecht L. Demographic Correlates of Short-Term Mortality Among Youth and Young Adults With Youth-Onset Diabetes Diagnosed From 2002 to 2015: The SEARCH for Diabetes in Youth Study. Diabetes Care. 2021 Dec;44(12):2691-2698. PubMed PMID: 34607833

Liu X, Vehik K, Huang Y, Larsson HE, Toppari J, Ziegler AG, She JX, Rewers M, Hagopian WA, Akolkar B, Krischer JP. Distinct Growth Phases in Early Life Associated With the Risk of Type 1 Diabetes: The TEDDY Study. Diabetes Care. 2020 Jan 2. [Epub ahead of print] PubMed PMID: 31896601

Lawrence JM, Slezak JM, Quesenberry C, Li X, Yu L, Rewers M, Alexander JG, Takhar HS, Sridhar S, Albright A, Rolka DB, Saydah S, Imperatore G, Ferrara A. Incidence and predictors of type 1 diabetes among younger adults aged 20-45 years: The diabetes in young adults (DiYA) study. Diabetes Res Clin Pract. 2020 Dec 15;171:108624. [Epub ahead of print] PubMed PMID: 33338552

Dunne JL, Koralova A, Sutphin J, Bushman JS, Fontanals-Ciera B, Coulter JR, Hutton CT, Rewers MJ, Mansfield C. Parent and Pediatrician Preferences for Type 1 Diabetes Screening in the U.S. Diabetes Care. 2020 Dec 10. [Epub ahead of print] PubMed PMID: 33303637

Onengut-Gumuscu S, Paila U, Chen WM, Ratan A, Zhu Z, Steck AK, Frohnert BI, Waugh KC, Webb-Robertson BM, Norris JM, Lange LA, Rewers MJ, Rich SS. Novel genetic risk factors influence progression of islet autoimmunity to type 1 diabetes. Sci Rep. 2020 Nov 5;10(1):19193. PubMed PMID: 33154504

Webb-Robertson BM, Bramer LM, Stanfill BA, Reehl SM, Nakayasu ES, Metz TO, Frohnert BI, Norris JM, Johnson RK, Rich SS, Rewers MJ. Prediction of the development of islet autoantibodies through integration of environmental, genetic, and metabolic markers. J Diabetes. 2020 Jul 22. [Epub ahead of print] PubMed PMID: 33124145

Steck AK, Liu X, Krischer JP, Haller MJ, Veijola R, Lundgren M, Ahmed S, Akolkar B, Toppari J, Hagopian WA, Rewers MJ, Elding Larsson H. Factors Associated with Decline of C-peptide in a Cohort of Young Children Diagnosed with Type 1 Diabetes. J Clin Endocrinol Metab. 2020 Oct 9. [Epub ahead of print] PubMed PMID: 33035311

Stahl MG, Dong F, Lamb MM, Waugh KC, Taki I, Størdal K, Stene LC, Rewers MJ, Liu E, Norris JM, Mårild K. Childhood growth prior to screen-detected celiac disease: prospective follow-up of an at-risk birth cohort. Scand J Gastroenterol. 2020 Nov;55(11):1284-1290. PubMed PMID: 32941083

Ferrat LA, Vehik K, Sharp SA, Lernmark Å, Rewers MJ, She JX, Ziegler AG, Toppari J, Akolkar B, Krischer JP, Weedon MN, Oram RA, Hagopian WA. A combined risk score enhances prediction of type 1 diabetes among susceptible children. Nat Med. 2020 Aug;26(8):1247-1255. PubMed PMID: 32770166

Vinovskis C, Li LP, Prasad P, Tommerdahl K, Pyle L, Nelson RG, Pavkov ME, van Raalte D, Rewers M, Pragnell M, Mahmud FH, Cherney DZ, Johnson RJ, Nadeau KJ, Bjornstad P. Relative Hypoxia and Early Diabetic Kidney Disease in Type 1 Diabetes. Diabetes. 2020 Dec;69(12):2700-2708. PubMed PMID: 32737116

Buckner T, Vanderlinden LA, Johnson RK, DeFelice BC, Carry PM, Seifert J, Waugh K, Dong F, Fiehn O, Clare-Salzler M, Rewers M, Norris JM. Predictors of oxylipins in a healthy pediatric population. Pediatr Res. 2020 Jul 29. [Epub ahead of print] PubMed PMID: 32726799

Johnson RK, Vanderlinden LA, DeFelice BC, Uusitalo U, Seifert J, Fan S, Crume T, Fiehn O, Rewers M, Kechris K, Norris JM. Metabolomics-related nutrient patterns at seroconversion and risk of progression to type 1 diabetes. Pediatr Diabetes. 2020 Jul 20. [Epub ahead of print] PubMed PMID: 32686271

Gardner JA, Johnson RK, Dong F, Hoffman M, Steck AK, Frohnert BI, Rewers M, Norris JM. Gluten intake and risk of thyroid peroxidase autoantibodies in the Diabetes Autoimmunity Study In the Young (DAISY). Endocrine. 2020 Nov;70(2):331-337. PubMed PMID: 32651851

Vehik K, Bonifacio E, Lernmark Å, Yu L, Williams A, Schatz D, Rewers M, She JX, Toppari J, Hagopian W, Akolkar B, Ziegler AG, Krischer JP. Hierarchical Order of Distinct Autoantibody Spreading and Progression to Type 1 Diabetes in the TEDDY Study. Diabetes Care. 2020 Sep;43(9):2066-2073. PubMed PMID: 32641373

Henze MM, Bemis EA, Seifert JA, Johnson RK, Dong F, Rewers M, Norris JM. Association between change in self-reported sugar intake and a sugar biomarker (d(13)C) in children at increased risk for type 1 diabetes. J Nutr Sci. 2020;9:e16. PubMed PMID: 32477498

McQueen RB, Geno Rasmussen C, Waugh K, Frohnert BI, Steck AK, Yu L, Baxter J, Rewers M. Cost and Cost-effectiveness of Large-scale Screening for Type 1 Diabetes in Colorado. Diabetes Care. 2020 Jul;43(7):1496-1503. PubMed PMID: 32327420

Johnson RK, Vanderlinden LA, Dong F, Carry PM, Seifert J, Waugh K, Shorrosh H, Fingerlin T, Frohnert BI, Yang IV, Kechris K, Rewers M, Norris JM. Longitudinal DNA methylation differences precede type 1 diabetes. Sci Rep. 2020 Feb 28;10(1):3721. PubMed PMID: 32111940

Carry PM, Vanderlinden LA, Johnson RK, Dong F, Steck AK, Frohnert BI, Rewers M, Yang IV, Kechris K, Norris JM. DNA methylation near the INS gene is associated with INS genetic variation (rs689) and type 1 diabetes in the Diabetes Autoimmunity Study in the Young. Pediatr Diabetes. 2020 Jun;21(4):597-605. PubMed PMID: 32061050

Li Q, Parikh H, Butterworth MD, Lernmark Å, Hagopian W, Rewers M, She JX, Toppari J, Ziegler AG, Akolkar B, Fiehn O, Fan S, Krischer JP. Longitudinal Metabolome-Wide Signals Prior to the Appearance of a First Islet Autoantibody in Children Participating in the TEDDY Study. Diabetes. 2020 Mar;69(3):465-476. PubMed PMID: 32029481

Chan CL, Steck AK, Severn C, Pyle L, Rewers M, Zeitler PS. Lessons From Continuous Glucose Monitoring in Youth With Pre-Type 1 Diabetes, Obesity, and Cystic Fibrosis. Diabetes Care. 2020 Mar;43(3):e35-e37. PubMed PMID: 31937609

Liu X, Vehik K, Huang Y, Elding Larsson H, Toppari J, Ziegler AG, She JX, Rewers M, Hagopian WA, Akolkar B, Krischer JP. Distinct Growth Phases in Early Life Associated With the Risk of Type 1 Diabetes: The TEDDY Study. Diabetes Care. 2020 Mar;43(3):556-562. PubMed PMID: 31896601

Sussman M, Benner J, Haller MJ, Rewers M, Griffiths R. Estimated Lifetime Economic Burden of Type 1 Diabetes. Diabetes Technol Ther. 2020 Feb;22(2):121-130. PubMed PMID: 31886730

Lindfors K, Lin J, Lee HS, Hyöty H, Nykter M, Kurppa K, Liu E, Koletzko S, Rewers M, Hagopian W, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Petrosino JF, Lloyd RE, Agardh D. Metagenomics of the faecal virome indicate a cumulative effect of enterovirus and gluten amount on the risk of coeliac disease autoimmunity in genetically at risk children: the TEDDY study. Gut. 2020 Aug;69(8):1416-1422. PubMed PMID: 31744911

Frohnert BI, Webb-Robertson BJ, Bramer LM, Reehl SM, Waugh K, Steck AK, Norris JM, Rewers M. Predictive Modeling of Type 1 Diabetes Stages Using Disparate Data Sources. Diabetes. 2020 Feb;69(2):238-248. PubMed PMID: 31740441

Mattila M, Erlund I, Lee HS, Niinistö S, Uusitalo U, Andrén Aronsson C, Hummel S, Parikh H, Rich SS, Hagopian W, Toppari J, Lernmark Å, Ziegler AG, Rewers M, Krischer JP, Norris JM, Virtanen SM. Plasma ascorbic acid and the risk of islet autoimmunity and type 1 diabetes: the TEDDY study. Diabetologia. 2020 Feb;63(2):278-286. PubMed PMID: 31728565

Halper-Stromberg E, Gallo T, Champakanath A, Taki I, Rewers M, Snell-Bergeon J, Frohnert BI, Shah VN. Bone Mineral Density across the Lifespan in Patients with Type 1 Diabetes. J Clin Endocrinol Metab. 2020 Mar 1;105(3). PubMed PMID: 31676897

Miller KM, Hermann J, Foster N, Hofer SE, Rickels MR, Danne T, Clements MA, Lilienthal E, Maahs DM, Holl RW. Longitudinal Changes in Continuous Glucose Monitoring Use Among Individuals With Type 1 Diabetes: International Comparison in the German and Austrian DPV and U.S. T1D Exchange Registries. Diabetes Care. 2020 Jan;43(1):e1-e2. PubMed PMID: 31672703

Mizokami-Stout KR, Li Z, Foster NC, Shah V, Aleppo G, McGill JB, Pratley R, Toschi E, Ang L, Pop-Busui R. The Contemporary Prevalence of Diabetic Neuropathy in Type 1 Diabetes: Findings From the T1D Exchange. Diabetes Care. 2020 Apr;43(4):806-812. PubMed PMID: 32029635

Tosur M, Cleves MA, Sosenko JM, Libman I, Baidal DA, Balasubramanyam A, Redondo MJ. The Effect of Ethnicity in the Rate of Beta-Cell Functional Loss in the First 3 Years After Type 1 Diabetes Diagnosis. J Clin Endocrinol Metab. 2020 Dec 1;105(12). PubMed PMID: 32502242

He L, Jia X, Gu Y, Miao D, Waugh K, Geno C, Liu E, Rewers M, Yu L. Large-Scale Screening in General Population Children for Celiac Disease with a Multiplex Electrochemiluminescence (ECL) Assay. J Immunol Res. 2020;2020:8897656. PubMed PMID: 33426098

Li Y, Liu B, Anand V, Dunne JL, Lundgren M, Ng K, Rewers M, Veijola R, Ghalwash M. Predicting Type 1 Diabetes Onset using Novel Survival Analysis with Biomarker Ontology. AMIA Annu Symp Proc. 2020;2020:727-736. PubMed PMID: 33936447

Vehik K, Lynch KF, Wong MC, Tian X, Ross MC, Gibbs RA, Ajami NJ, Petrosino JF, Rewers M, Toppari J, Ziegler AG, She JX, Lernmark A, Akolkar B, Hagopian WA, Schatz DA, Krischer JP, Hyöty H, Lloyd RE. Prospective virome analyses in young children at increased genetic risk for type 1 diabetes. Nat Med. 2019 Dec;25(12):1865-1872. PubMed PMID: 31792456

Lindfors K, Lin J, Lee HS, Hyöty H, Nykter M, Kurppa K, Liu E, Koletzko S, Rewers M, Hagopian W, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Petrosino JF, Lloyd RE, Agardh D. Metagenomics of the faecal virome indicate a cumulative effect of enterovirus and gluten amount on the risk of coeliac disease autoimmunity in genetically at risk children: the TEDDY study. Gut. 2019 Nov 19. [Epub ahead of print] PubMed PMID: 31744911

Mattila M, Erlund I, Lee HS, Niinistö S, Uusitalo U, Andrén Aronsson C, Hummel S, Parikh H, Rich SS, Hagopian W, Toppari J, Lernmark Å, Ziegler AG, Rewers M, Krischer JP, Norris JM, Virtanen SM. Plasma ascorbic acid and the risk of islet autoimmunity and type 1 diabetes: the TEDDY study. Diabetologia. 2019 Nov 14. [Epub ahead of print] PubMed PMID: 31728565

Halper-Stromberg E, Gallo T, Champakanath A, Taki I, Rewers M, Snell-Bergeon J, Frohnert BI, Shah VN. Bone Mineral Density across the Life-Span in Patients with Type 1 Diabetes. J Clin Endocrinol Metab. 2019 Nov 2. [Epub ahead of print] PubMed PMID: 31676897

Mina MJ, Kula T, Leng Y, Li M, de Vries RD, Knip M, Siljander H, Rewers M, Choy DF, Wilson MS, Larman HB, Nelson AN, Griffin DE, de Swart RL, Elledge SJ. Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens. Science. 2019 Nov 1;366(6465):599-606. PubMed PMID: 31672891

Johnson RK, Vanderlinden L, DeFelice BC, Kechris K, Uusitalo U, Fiehn O, Sontag M, Crume T, Beyerlein A, Lernmark Å, Toppari J, Ziegler AG, She JX, Hagopian W, Rewers M, Akolkar B, Krischer J, Virtanen SM, Norris JM. Metabolite-related dietary patterns and the development of islet autoimmunity. Sci Rep. 2019 Oct 15;9(1):14819. PubMed PMID: 31616039

Gu Y, Zhao Z, Waugh K, Miao D, Jia X, Cheng J, Michels A, Rewers M, Yang T, Yu L. High-throughput multiplexed autoantibody detection to screen type 1 diabetes and multiple autoimmune diseases simultaneously. EBioMedicine. 2019 Sep;47:365-372. PubMed PMID: 31447394

Andrén Aronsson C, Lee HS, Hård Af Segerstad EM, Uusitalo U, Yang J, Koletzko S, Liu E, Kurppa K, Bingley PJ, Toppari J, Ziegler AG, She JX, Hagopian WA, Rewers M, Akolkar B, Krischer JP, Virtanen SM, Norris JM, Agardh D. Association of Gluten Intake During the First 5 Years of Life With Incidence of Celiac Disease Autoimmunity and Celiac Disease Among Children at Increased Risk. JAMA. 2019 Aug 13;322(6):514-523. PubMed PMID: 31408136

Uusitalo U, Andren Aronsson C, Liu X, Kurppa K, Yang J, Liu E, Skidmore J, Winkler C, Rewers MJ, Hagopian WA, She JX, Toppari J, Ziegler AG, Akolkar B, Norris JM, Virtanen SM, Krischer JP, Agardh D. Early Probiotic Supplementation and the Risk of Celiac Disease in Children at Genetic Risk. Nutrients. 2019 Aug 2;11(8). PubMed PMID: 31382440

Stanfill B, Reehl S, Bramer L, Nakayasu ES, Rich SS, Metz TO, Rewers M, Webb-Robertson BJ. Extending Classification Algorithms to Case-Control Studies. Biomed Eng Comput Biol. 2019;10:1179597219858954. PubMed PMID: 31320812

Vu N, Narvaez-Rivas M, Chen GY, Rewers MJ, Zhang Q. Accurate mass and retention time library of serum lipids for type 1 diabetes research. Anal Bioanal Chem. 2019 Sep;411(23):5937-5949. PubMed PMID: 31280478

Mårild K, Dong F, Lund-Blix NA, Seifert J, Barón AE, Waugh KC, Taki I, Størdal K, Tapia G, Stene LC, Johnson RK, Liu E, Rewers MJ, Norris JM. Gluten Intake and Risk of Celiac Disease: Long-Term Follow-up of an At-Risk Birth Cohort. Am J Gastroenterol. 2019 Aug;114(8):1307-1314. PubMed PMID: 31082869

Mårild K, Tapia G, Midttun Ø, Ueland PM, Magnus MC, Rewers M, Stene LC, Størdal K. Smoking in pregnancy, cord blood cotinine and risk of celiac disease diagnosis in offspring. Eur J Epidemiol. 2019 Jul;34(7):637-649. PubMed PMID: 31037572

Steck AK, Dong F, Taki I, Hoffman M, Simmons K, Frohnert BI, Rewers MJ. Continuous Glucose Monitoring Predicts Progression to Diabetes in Autoantibody Positive Children. J Clin Endocrinol Metab. 2019 Aug 1;104(8):3337-3344. PubMed PMID: 30844073

Krischer JP, Liu X, Vehik K, Akolkar B, Hagopian WA, Rewers MJ, She JX, Toppari J, Ziegler AG, Lernmark Å. Predicting Islet Cell Autoimmunity and Type 1 Diabetes: An 8-Year TEDDY Study Progress Report. Diabetes Care. 2019 Jun;42(6):1051-1060. PubMed PMID: 30967432

Lund-Blix NA, Dong F, Mårild K, Seifert J, Barón AE, Waugh KC, Joner G, Størdal K, Tapia G, Stene LC, Johnson RK, Rewers MJ, Norris JM. Gluten Intake and Risk of Islet Autoimmunity and Progression to Type 1 Diabetes in Children at Increased Risk of the Disease: The Diabetes Autoimmunity Study in the Young (DAISY). Diabetes Care. 2019 May;42(5):789-796. PubMed PMID: 30796108

Syreeni A, Sandholm N, Cao J, Toppila I, Maahs DM, Rewers MJ, Snell-Bergeon JK, Costacou T, Orchard TJ, Caramori ML, Mauer M, Klein BEK, Klein R, Valo E, Parkkonen M, Forsblom C, Harjutsalo V, Paterson AD, Groop PH. Genetic Determinants of Glycated Hemoglobin in Type 1 Diabetes. Diabetes. 2019 Apr;68(4):858-867. PubMed PMID: 30674623

Onengut-Gumuscu S, Chen WM, Robertson CC, Bonnie JK, Farber E, Zhu Z, Oksenberg JR, Brant SR, Bridges SL Jr, Edberg JC, Kimberly RP, Gregersen PK, Rewers MJ, Steck AK, Black MH, Dabelea D, Pihoker C, Atkinson MA, Wagenknecht LE, Divers J, Bell RA, Erlich HA, Concannon P, Rich SS. Type 1 Diabetes Risk in African-Ancestry Participants and Utility of an Ancestry-Specific Genetic Risk Score. Diabetes Care. 2019 Mar;42(3):406-415. PubMed PMID: 30659077

Hippich M, Beyerlein A, Hagopian WA, Krischer JP, Vehik K, Knoop J, Winker C, Toppari J, Lernmark Å, Rewers MJ, Steck AK, She JX, Akolkar B, Robertson CC, Onengut-Gumuscu S, Rich SS, Bonifacio E, Ziegler AG. Genetic Contribution to the Divergence in Type 1 Diabetes Risk Between Children From the General Population and Children From Affected Families. Diabetes. 2019 Apr;68(4):847-857. PubMed PMID: 30655385

Jacobsen LM, Larsson HE, Tamura RN, Vehik K, Clasen J, Sosenko J, Hagopian WA, She JX, Steck AK, Rewers M, Simell O, Toppari J, Veijola R, Ziegler AG, Krischer JP, Akolkar B, Haller MJ. Predicting progression to type 1 diabetes from ages 3 to 6 in islet autoantibody positive TEDDY children. Pediatr Diabetes. 2019 May;20(3):263-270. PubMed PMID: 30628751

Frohnert BI, Webb-Robertson BJ, Bramer LM, Reehl SM, Waugh K, Steck AK, Norris JM, Rewers M. Predictive Modeling of Type 1 Diabetes Stages Using Disparate Data Sources. Diabetes. 2019 Nov 18. [Epub ahead of print] PubMed PMID: 31740441

Sussman M, Benner J, Haller M, Rewers M, Griffiths R. Estimated Lifetime Economic Burden of Type 1 Diabetes. Diabetes Technol Ther. 2019 Dec 30. [Epub ahead of print] PubMed PMID: 31886730

Jensen T, Bjornstad P, Johnson RJ, Sippl R, Rewers M, Snell-Bergeon JK. Copeptin and Estimated Insulin Sensitivity in Adults With and Without Type 1 Diabetes: The CACTI Study. Can J Diabetes. 2019 Feb;43(1):34-39. PubMed PMID: 30026043

Beyerlein A, Bonifacio E, Vehik K, Hippich M, Winkler C, Frohnert BI, Steck AK, Hagopian WA, Krischer JP, Lernmark Å, Rewers MJ, She JX, Toppari J, Akolkar B, Rich SS, Ziegler AG. Progression from islet autoimmunity to clinical type 1 diabetes is influenced by genetic factors: results from the prospective TEDDY study. J Med Genet. 2019 Sep;56(9):602-605. PubMed PMID: 30287597

Endesfelder D, Zu Castell W, Bonifacio E, Rewers M, Hagopian WA, She JX, Lernmark Å, Toppari J, Vehik K, Williams AJK, Yu L, Akolkar B, Krischer JP, Ziegler AG, Achenbach P. Time-Resolved Autoantibody Profiling Facilitates Stratification of Preclinical Type 1 Diabetes in Children. Diabetes. 2019 Jan;68(1):119-130. PubMed PMID: 30305370

Bjornstad P, Singh SK, Snell-Bergeon JK, Lovshin JA, Lytvyn Y, Lovblom LE, Rewers MJ, Boulet G, Lai V, Tse J, Cham L, Orszag A, Weisman A, Keenan HA, Brent MH, Paul N, Bril V, Perkins BA, Cherney DZI. The relationships between markers of tubular injury and intrarenal haemodynamic function in adults with and without type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes. Diabetes Obes Metab. 2019 Mar;21(3):575-583. PubMed PMID: 30311395

Silvis K, Aronsson CA, Liu X, Uusitalo U, Yang J, Tamura R, Lernmark Å, Rewers M, Hagopian W, She JX, Simell O, Toppari J, Ziegler A, Akolkar B, Krischer J, Virtanen SM, Norris JM. Maternal dietary supplement use and development of islet autoimmunity in the offspring: TEDDY study. Pediatr Diabetes. 2019 Feb;20(1):86-92. PubMed PMID: 30411443

Bjornstad P, Wiromrat P, Johnson RJ, Sippl R, Cherney DZI, Wong R, Rewers MJ, Snell-Bergeon JK. Serum Uromodulin Predicts Less Coronary Artery Calcification and Diabetic Kidney Disease Over 12 Years in Adults With Type 1 Diabetes: The CACTI Study. Diabetes Care. 2019 Feb;42(2):297-302. PubMed PMID: 30482755

Liu CW, Bramer L, Webb-Robertson BJ, Waugh K, Rewers MJ, Zhang Q. Temporal expression profiling of plasma proteins reveals oxidative stress in early stages of Type 1 Diabetes progression. J Proteomics. 2018 Feb 10;172:100-110. PubMed PMID: 28993202

Bjornstad P, Wiromrat P, Johnson RJ, Sippl R, Cherney DZ, Wong R, Rewers MJ, Snell-Bergeon JK. Serum Uromodulin Predicts Less Coronary Artery Calcification and Diabetic Kidney Disease Over 12 years in Adults With Type 1 Diabetes: The CACTI Study. Diabetes Care. 2018 Nov 27. [Epub ahead of print] PubMed PMID: 30482755

Silvis K, Aronsson CA, Liu X, Uusitalo U, Yang J, Tamura R, Lernmark Å, Rewers M, Hagopian W, She JX, Simell O, Toppari J, Ziegler A, Akolkar B, Krischer J, Virtanen SM, Norris JM. Maternal Dietary Supplement Use and Development of Islet Autoimmunity in the offspring: the TEDDY Study. Pediatr Diabetes. 2018 Nov 8. [Epub ahead of print] PubMed PMID: 30411443

Stewart CJ, Ajami NJ, O'Brien JL, Hutchinson DS, Smith DP, Wong MC, Ross MC, Lloyd RE, Doddapaneni H, Metcalf GA, Muzny D, Gibbs RA, Vatanen T, Huttenhower C, Xavier RJ, Rewers M, Hagopian W, Toppari J, Ziegler AG, She JX, Akolkar B, Lernmark A, Hyoty H, Vehik K, Krischer JP, Petrosino JF. Temporal development of the gut microbiome in early childhood from the TEDDY study. Nature. 2018 Oct;562(7728):583-588. PubMed PMID: 30356187

Vatanen T, Franzosa EA, Schwager R, Tripathi S, Arthur TD, Vehik K, Lernmark Å, Hagopian WA, Rewers MJ, She JX, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Stewart CJ, Ajami NJ, Petrosino JF, Gevers D, Lähdesmäki H, Vlamakis H, Huttenhower C, Xavier RJ. The human gut microbiome in early-onset type 1 diabetes from the TEDDY study. Nature. 2018 Oct;562(7728):589-594. PubMed PMID: 30356183

Rewers M, Hyöty H, Lernmark Å, Hagopian W, She JX, Schatz D, Ziegler AG, Toppari J, Akolkar B, Krischer J. The Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update. Curr Diab Rep. 2018 Oct 23;18(12):136. PubMed PMID: 30353256

Bjornstad P, Singh SK, Snell-Bergeon JK, Lovshin JA, Lytvyn Y, Lovblom LE, Rewers MJ, Boulet G, Lai V, Tse J, Cham L, Orszag A, Weisman A, Keenan HA, Brent MH, Paul N, Bril V, Perkins BA, Cherney DZI. The relationships between markers of tubular injury and intrarenal haemodynamic function in adults with and without type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes. Diabetes Obes Metab. 2018 Oct 12. [Epub ahead of print] PubMed PMID: 30311395

Endesfelder D, Castell WZ, Bonifacio E, Rewers M, Hagopian WA, She JX, Lernmark Å, Toppari J, Vehik K, Williams AJK, Yu L, Akolkar B, Krischer JP, Ziegler AG, Achenbach P. Time-Resolved Autoantibody Profiling Facilitates Stratification of Preclinical Type 1 Diabetes in Children. Diabetes. 2018 Oct 10. [Epub ahead of print] PubMed PMID: 30305370

Beyerlein A, Bonifacio E, Vehik K, Hippich M, Winkler C, Frohnert BI, Steck AK, Hagopian WA, Krischer JP, Lernmark Å, Rewers MJ, She JX, Toppari J, Akolkar B, Rich SS, Ziegler AG. Progression from islet autoimmunity to clinical type 1 diabetes is influenced by genetic factors: results from the prospective TEDDY study. J Med Genet. 2018 Oct 4. [Epub ahead of print] PubMed PMID: 30287597

Jensen T, Bjornstad P, Johnson RJ, Sippl R, Rewers M, Snell-Bergeon JK. Copeptin and Estimated Insulin Sensitivity in Adults With and Without Type 1 Diabetes: The CACTI Study. Can J Diabetes. 2018 Mar 14. [Epub ahead of print] PubMed PMID: 30026043

Bonifacio E, Beyerlein A, Hippich M, Winkler C, Vehik K, Weedon MN, Laimighofer M, Hattersley AT, Krumsiek J, Frohnert BI, Steck AK, Hagopian WA, Krischer JP, Lernmark Å, Rewers MJ, She JX, Toppari J, Akolkar B, Oram RA, Rich SS, Ziegler AG. Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children. PLoS Med. 2018 Apr;15(4):e1002548. PubMed PMID: 29614081

Smith LB, Liu X, Johnson SB, Tamura R, Elding Larsson H, Ahmed S, Veijola R, Haller MJ, Akolkar B, Hagopian WA, Rewers MJ, Krischer J, Steck AK. Family adjustment to diabetes diagnosis in children: Can participation in a study on type 1 diabetes genetic risk be helpful?. Pediatr Diabetes. 2018 Aug;19(5):1025-1033. PubMed PMID: 29577538

Long AE, Wilson IV, Becker DJ, Libman IM, Arena VC, Wong FS, Steck AK, Rewers MJ, Yu L, Achenbach P, Casas R, Ludvigsson J, Williams AJK, Gillespie KM. Characteristics of slow progression to diabetes in multiple islet autoantibody-positive individuals from five longitudinal cohorts: the SNAIL study. Diabetologia. 2018 Jun;61(6):1484-1490. PubMed PMID: 29532109

Bjornstad P, Maahs DM, Roncal CA, Snell-Bergeon JK, Shah VN, Milagres T, Ellis SL, Hatch M, Chung LT, Rewers MJ, Garg S, Cherney DZ, Pyle L, Nadeau KJ, Johnson RJ. Role of bicarbonate supplementation on urine uric acid crystals and diabetic tubulopathy in adults with type 1 diabetes. Diabetes Obes Metab. 2018 Jul;20(7):1776-1780. PubMed PMID: 29498467

Millstein RJ, Pyle LL, Bergman BC, Eckel RH, Maahs DM, Rewers MJ, Schauer IE, Snell-Bergeon JK. Sex-specific differences in insulin resistance in type 1 diabetes: The CACTI cohort. J Diabetes Complications. 2018 Apr;32(4):418-423. PubMed PMID: 29449137

Steck AK, Dong F, Frohnert BI, Waugh K, Hoffman M, Norris JM, Rewers MJ. Predicting progression to diabetes in islet autoantibody positive children. J Autoimmun. 2018 Jun;90:59-63. PubMed PMID: 29395739

Uusitalo U, Lee HS, Andrén Aronsson C, Vehik K, Yang J, Hummel S, Silvis K, Lernmark Å, Rewers M, Hagopian W, She JX, Simell O, Toppari J, Ziegler AG, Akolkar B, Krischer J, Virtanen SM, Norris JM. Early Infant Diet and Islet Autoimmunity in the TEDDY Study. Diabetes Care. 2018 Mar;41(3):522-530. PubMed PMID: 29343517

Sharma A, Liu X, Hadley D, Hagopian W, Chen WM, Onengut-Gumuscu S, Törn C, Steck AK, Frohnert BI, Rewers M, Ziegler AG, Lernmark Å, Toppari J, Krischer JP, Akolkar B, Rich SS, She JX. Identification of non-HLA genes associated with development of islet autoimmunity and type 1 diabetes in the prospective TEDDY cohort. J Autoimmun. 2018 May;89:90-100. PubMed PMID: 29310926

Abbott JK, Huoh YS, Reynolds PR, Yu L, Rewers M, Reddy M, Anderson MS, Hur S, Gelfand EW. Dominant-negative loss of function arises from a second, more frequent variant within the SAND domain of autoimmune regulator (AIRE). J Autoimmun. 2018 Mar;88:114-120. PubMed PMID: 29129473

Lönnrot M, Lynch KF, Elding Larsson H, Lernmark Å, Rewers MJ, Törn C, Burkhardt BR, Briese T, Hagopian WA, She JX, Simell OG, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Hyöty H. Correction to: Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: the TEDDY study. Diabetologia. 2018 Jan;61(1):254. PubMed PMID: 29080005

Norris JM, Lee HS, Frederiksen B, Erlund I, Uusitalo U, Yang J, Lernmark Å, Simell O, Toppari J, Rewers M, Ziegler AG, She JX, Onengut-Gumuscu S, Chen WM, Rich SS, Sundvall J, Akolkar B, Krischer J, Virtanen SM, Hagopian W. Plasma 25-Hydroxyvitamin D Concentration and Risk of Islet Autoimmunity. Diabetes. 2018 Jan;67(1):146-154. PubMed PMID: 29061729

Liu CW, Bramer L, Webb-Robertson BJ, Waugh K, Rewers MJ, Zhang Q. Temporal expression profiling of plasma proteins reveals oxidative stress in early stages of Type 1 Diabetes progression. J Proteomics. 2018 Feb 10;172:100-110. PubMed PMID: 28993202

Bjornstad P, Pyle L, Cherney DZI, Johnson RJ, Sippl R, Wong R, Rewers M, Snell-Bergeon JK. Plasma biomarkers improve prediction of diabetic kidney disease in adults with type 1 diabetes over a 12-year follow-up: CACTI study. Nephrol Dial Transplant. 2018 Jul 1;33(7):1189-1196. PubMed PMID: 28992280

Elding Larsson H, Lynch KF, Lönnrot M, Haller MJ, Lernmark Å, Hagopian WA, She JX, Simell O, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Rewers MJ, Hyöty H. Pandemrix® vaccination is not associated with increased risk of islet autoimmunity or type 1 diabetes in the TEDDY study children. Diabetologia. 2018 Jan;61(1):193-202. PubMed PMID: 28990147

Lynch KF, Lee HS, Törn C, Vehik K, Krischer JP, Larsson HE, Haller MJ, Hagopian WA, Rewers MJ, She JX, Simell OG, Toppari J, Ziegler AG, Akolkar B, Hyöty H, Bonifacio E, Lernmark Å. Gestational respiratory infections interacting with offspring HLA and CTLA-4 modifies incident ß-cell autoantibodies. J Autoimmun. 2018 Jan;86:93-103. PubMed PMID: 28941965

Koletzko S, Lee HS, Beyerlein A, Aronsson CA, Hummel M, Liu E, Simell V, Kurppa K, Lernmark Å, Hagopian W, Rewers M, She JX, Simell O, Toppari J, Ziegler AG, Krischer J, Agardh D. Cesarean Section on the Risk of Celiac Disease in the Offspring: The Teddy Study. J Pediatr Gastroenterol Nutr. 2018 Mar;66(3):417-424. PubMed PMID: 28753178

Frohnert BI, Laimighofer M, Krumsiek J, Theis FJ, Winkler C, Norris JM, Ziegler AG, Rewers MJ, Steck AK. Prediction of type 1 diabetes using a genetic risk model in the Diabetes Autoimmunity Study in the Young. Pediatr Diabetes. 2018 Mar;19(2):277-283. PubMed PMID: 28695611

Hagopian W, Lee HS, Liu E, Rewers M, She JX, Ziegler AG, Lernmark Å, Toppari J, Rich SS, Krischer JP, Erlich H, Akolkar B, Agardh D. Co-occurrence of Type 1 Diabetes and Celiac Disease Autoimmunity. Pediatrics. 2017 Nov;140(5). PubMed PMID: 29018046

Bjornstad P, Pyle L, Cherney DZI, Johnson RJ, Sippl R, Wong R, Rewers M, Snell-Bergeon JK. Plasma biomarkers improve prediction of diabetic kidney disease in adults with type 1 diabetes over a 12-year follow-up: CACTI study. Nephrol Dial Transplant. 2017 Aug 21. [Epub ahead of print] PubMed PMID: 28992280

Santaren ID, Watkins SM, Liese AD, Wagenknecht LE, Rewers MJ, Haffner SM, Lorenzo C, Festa A, Bazinet RP, Hanley AJ. Individual serum saturated fatty acids and markers of chronic subclinical inflammation: the Insulin Resistance Atherosclerosis Study. J Lipid Res. 2017 Nov;58(11):2171-2179. PubMed PMID: 28928169

Krischer JP, Liu X, Lernmark Å, Hagopian WA, Rewers MJ, She JX, Toppari J, Ziegler AG, Akolkar B. The Influence of Type 1 Diabetes Genetic Susceptibility Regions, Age, Sex, and Family History on the Progression From Multiple Autoantibodies to Type 1 Diabetes: A TEDDY Study Report. Diabetes. 2017 Dec;66(12):3122-3129. PubMed PMID: 28903990

Köhler M, Beyerlein A, Vehik K, Greven S, Umlauf N, Lernmark Å, Hagopian WA, Rewers M, She JX, Toppari J, Akolkar B, Krischer JP, Bonifacio E, Ziegler AG. Joint modeling of longitudinal autoantibody patterns and progression to type 1 diabetes: results from the TEDDY study. Acta Diabetol. 2017 Nov;54(11):1009-1017. PubMed PMID: 28856522

Lönnrot M, Lynch KF, Elding Larsson H, Lernmark Å, Rewers MJ, Törn C, Burkhardt BR, Briese T, Hagopian WA, She JX, Simell OG, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Hyöty H. Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: the TEDDY study. Diabetologia. 2017 Oct;60(10):1931-1940. PubMed PMID: 28770319

Koletzko S, Lee HS, Beyerlein A, Aronsson CA, Hummel M, Liu E, Simell V, Kurppa K, Lernmark Å, Hagopian W, Rewers M, She JX, Simell O, Toppari J, Ziegler AG, Krischer J, Agardh D. Caesarean Section on The Risk of Celiac Disease in the Offspring: The Teddy Study. J Pediatr Gastroenterol Nutr. 2017 Jul 27. [Epub ahead of print] PubMed PMID: 28753178

Bjornstad P, Costacou T, Miller RG, Maahs DM, Rewers MJ, Orchard TJ, Snell-Bergeon JK. Predictors of early renal function decline in adults with Type 1 diabetes: the Coronary Artery Calcification in Type 1 Diabetes and the Pittsburgh Epidemiology of Diabetes Complications studies. Diabet Med. 2017 Nov;34(11):1532-1540. PubMed PMID: 28734104

Duca LM, Wang B, Rewers M, Rewers A. Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes Predicts Poor Long-term Glycemic Control. Diabetes Care. 2017 Sep;40(9):1249-1255. PubMed PMID: 28667128

Krischer JP, Lynch KF, Lernmark Å, Hagopian WA, Rewers MJ, She JX, Toppari J, Ziegler AG, Akolkar B. Genetic and Environmental Interactions Modify the Risk of Diabetes-Related Autoimmunity by 6 Years of Age: The TEDDY Study. Diabetes Care. 2017 Sep;40(9):1194-1202. PubMed PMID: 28646072

Mårild K, Størdal K, Bulik CM, Rewers M, Ekbom A, Liu E, Ludvigsson JF. Celiac Disease and Anorexia Nervosa: A Nationwide Study. Pediatrics. 2017 May;139(5). PubMed PMID: 28557761

Lundgren M, Steed LJ, Tamura R, Jonsdottir B, Gesualdo P, Crouch C, Sjöberg M, Hansson G, Hagopian WA, Ziegler AG, Rewers MJ, Lernmark Å, Toppari J, She JX, Akolkar B, Krischer JP, Haller MJ, Elding Larsson H. Analgesic antipyretic use among young children in the TEDDY study: no association with islet autoimmunity. BMC Pediatr. 2017 May 16;17(1):127. PubMed PMID: 28511706

Yang J, Tamura RN, Aronsson CA, Uusitalo UM, Lernmark Å, Rewers M, Hagopian WA, She JX, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Norris JM, Virtanen SM, Agardh D. Maternal use of dietary supplements during pregnancy is not associated with coeliac disease in the offspring: The Environmental Determinants of Diabetes in the Young (TEDDY) study. Br J Nutr. 2017 Feb;117(3):466-472. PubMed PMID: 28249640

Steck AK, Larsson HE, Liu X, Veijola R, Toppari J, Hagopian WA, Haller MJ, Ahmed S, Akolkar B, Lernmark Å, Rewers MJ, Krischer JP. Residual beta-cell function in diabetes children followed and diagnosed in the TEDDY study compared to community controls. Pediatr Diabetes. 2017 Dec;18(8):794-802. PubMed PMID: 28127835

Hummel S, Beyerlein A, Tamura R, Uusitalo U, Andrén Aronsson C, Yang J, Riikonen A, Lernmark Å, Rewers MJ, Hagopian WA, She JX, Simell OG, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Virtanen SM, Norris JM. First Infant Formula Type and Risk of Islet Autoimmunity in The Environmental Determinants of Diabetes in the Young (TEDDY) Study. Diabetes Care. 2017 Mar;40(3):398-404. PubMed PMID: 28096222

Lorenzo C, Festa A, Hanley AJ, Rewers MJ, Escalante A, Haffner SM. Novel Protein Glycan-Derived Markers of Systemic Inflammation and C-Reactive Protein in Relation to Glycemia, Insulin Resistance, and Insulin Secretion. Diabetes Care. 2017 Mar;40(3):375-382. PubMed PMID: 28031420

Liu CW, Bramer L, Webb-Robertson BJ, Waugh K, Rewers MJ, Zhang Q. Temporal profiles of plasma proteome during childhood development. J Proteomics. 2017 Jan 30;152:321-328. PubMed PMID: 27890796

Kemppainen KM, Lynch KF, Liu E, Lönnrot M, Simell V, Briese T, Koletzko S, Hagopian W, Rewers M, She JX, Simell O, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Lernmark Å, Hyöty H, Triplett EW, Agardh D. Factors That Increase Risk of Celiac Disease Autoimmunity After a Gastrointestinal Infection in Early Life. Clin Gastroenterol Hepatol. 2017 May;15(5):694-702.e5. PubMed PMID: 27840181

Bjornstad P, Pyle L, Kinney GL, Rewers M, Johnson RJ, Maahs DM, Snell-Bergeon JK. Adiponectin is associated with early diabetic kidney disease in adults with type 1 diabetes: A Coronary Artery Calcification in Type 1 Diabetes (CACTI) Study. J Diabetes Complications. 2017 Feb;31(2):369-374. PubMed PMID: 27368123

Craig ME, Prinz N, Boyle CT, Campbell FM, Jones TW, Hofer SE, Simmons JH, Holman N, Tham E, Fröhlich-Reiterer E, DuBose S, Thornton H, King B, Maahs DM, Holl RW, Warner JT. Prevalence of Celiac Disease in 52,721 Youth With Type 1 Diabetes: International Comparison Across Three Continents. Diabetes Care. 2017 Aug;40(8):1034-1040. PubMed PMID: 28546222

Mayer-Davis EJ, Lawrence JM, Dabelea D, Divers J, Isom S, Dolan L, Imperatore G, Linder B, Marcovina S, Pettitt DJ, Pihoker C, Saydah S, Wagenknecht L. Incidence Trends of Type 1 and Type 2 Diabetes among Youths, 2002-2012. N Engl J Med. 2017 Apr 13;376(15):1419-1429. PubMed PMID: 28402773

Uusitalo U, Liu X, Yang J, Aronsson CA, Hummel S, Butterworth M, Lernmark Å, Rewers M, Hagopian W, She JX, Simell O, Toppari J, Ziegler AG, Akolkar B, Krischer J, Norris JM, Virtanen SM. Association of Early Exposure of Probiotics and Islet Autoimmunity in the TEDDY Study. JAMA Pediatr. 2016 Jan 1;170(1):20-28. PubMed PMID: 26552054

Lorenzo C, Festa A, Hanley AJ, Rewers MJ, Escalante A, Haffner SM. Novel Protein Glycan-Derived Markers of Systemic Inflammation and C-Reactive Protein in Relation to Glycemia, Insulin Resistance, and Insulin Secretion. Diabetes Care. 2016 Dec 28. [Epub ahead of print] PubMed PMID: 28031420

Liu CW, Bramer L, Webb-Robertson BJ, Waugh K, Rewers MJ, Zhang Q. Temporal profiles of plasma proteome during childhood development. J Proteomics. 2016 Nov 23;152:321-328. [Epub ahead of print] PubMed PMID: 27890796

Kemppainen KM, Lynch KF, Liu E, Lönnrot M, Simell V, Briese T, Koletzko S, Hagopian W, Rewers M, She JX, Simell O, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Lernmark Å, Hyöty H, Triplett EW, Agardh D. Factors that Increase Risk of Celiac Disease Autoimmunity Following a Gastrointestinal Infection in Early Life. Clin Gastroenterol Hepatol. 2016 Nov 10. [Epub ahead of print] PubMed PMID: 27840181

Bjornstad P, Pyle L, Kinney GL, Rewers M, Johnson RJ, Maahs DM, Snell-Bergeon JK. Adiponectin is associated with early diabetic kidney disease in adults with type 1 diabetes: A Coronary Artery Calcification in Type 1 Diabetes (CACTI) Study. J Diabetes Complications. 2016 Jun 14. [Epub ahead of print] PubMed PMID: 27368123

Vehik K, Lynch KF, Schatz DA, Akolkar B, Hagopian W, Rewers M, She JX, Simell O, Toppari J, Ziegler AG, Lernmark Å, Bonifacio E, Krischer JP. Reversion of ß-Cell Autoimmunity Changes Risk of Type 1 Diabetes: TEDDY Study. Diabetes Care. 2016 Sep;39(9):1535-42. PubMed PMID: 27311490

Törn C, Liu X, Hagopian W, Lernmark Å, Simell O, Rewers M, Ziegler AG, Schatz D, Akolkar B, Onengut-Gumuscu S, Chen WM, Toppari J, Mykkänen J, Ilonen J, Rich SS, She JX, Sharma A, Steck A, Krischer J. Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study. Sci Rep. 2016 Jun 16;6:27887. PubMed PMID: 27306948

Rewers M, Ludvigsson J. Environmental risk factors for type 1 diabetes. Lancet. 2016 Jun 4;387(10035):2340-8. PubMed PMID: 27302273

Steck AK, Dong F, Waugh K, Frohnert BI, Yu L, Norris JM, Rewers MJ. Predictors of slow progression to diabetes in children with multiple islet autoantibodies. J Autoimmun. 2016 Aug;72:113-7. PubMed PMID: 27255734

Bjornstad P, Maahs DM, Jensen T, Lanaspa MA, Johnson RJ, Rewers M, Snell-Bergeon JK. Elevated copeptin is associated with atherosclerosis and diabetic kidney disease in adults with type 1 diabetes. J Diabetes Complications. 2016 Aug;30(6):1093-6. PubMed PMID: 27141815

Sharma A, Liu X, Hadley D, Hagopian W, Liu E, Chen WM, Onengut-Gumuscu S, Simell V, Rewers M, Ziegler AG, Lernmark Å, Simell O, Toppari J, Krischer JP, Akolkar B, Rich SS, Agardh D, She JX. Identification of Non-HLA Genes Associated with Celiac Disease and Country-Specific Differences in a Large, International Pediatric Cohort. PLoS One. 2016 Mar 25;11(3):e0152476. PubMed PMID: 27015091

Elding Larsson H, Vehik K, Haller MJ, Liu X, Akolkar B, Hagopian W, Krischer J, Lernmark Å, She JX, Simell O, Toppari J, Ziegler AG, Rewers M. Growth and Risk for Islet Autoimmunity and Progression to Type 1 Diabetes in Early Childhood: The Environmental Determinants of Diabetes in the Young Study. Diabetes. 2016 Jul;65(7):1988-95. PubMed PMID: 26993064

Steck AK, Fouts A, Miao D, Zhao Z, Dong F, Sosenko J, Gottlieb P, Rewers MJ, Yu L. ECL-IAA and ECL-GADA Can Identify High-Risk Single Autoantibody-Positive Relatives in the TrialNet Pathway to Prevention Study. Diabetes Technol Ther. 2016 Jul;18(7):410-4. PubMed PMID: 26991969

Bjornstad P, Maahs DM, Duca LM, Pyle L, Rewers M, Johnson RJ, Snell-Bergeon JK. Estimated insulin sensitivity predicts incident micro- and macrovascular complications in adults with type 1 diabetes over 6 years: the coronary artery calcification in type 1 diabetes study. J Diabetes Complications. 2016 May-Jun;30(4):586-90. PubMed PMID: 26936306

Zhao Z, Miao D, Michels A, Steck A, Dong F, Rewers M, Yu L. A multiplex assay combining insulin, GAD, IA-2 and transglutaminase autoantibodies to facilitate screening for pre-type 1 diabetes and celiac disease. J Immunol Methods. 2016 Mar;430:28-32. PubMed PMID: 26809048

Duca LM, Maahs DM, Schauer IE, Bergman BC, Nadeau KJ, Bjornstad P, Rewers M, Snell-Bergeon JK. Development and Validation of a Method to Estimate Insulin Sensitivity in Patients With and Without Type 1 Diabetes. J Clin Endocrinol Metab. 2016 Feb;101(2):686-95. PubMed PMID: 26672636

Simmons KM, McFann K, Taki I, Liu E, Klingensmith GJ, Rewers MJ, Frohnert BI. Reduced Bone Mineral Density Is Associated with Celiac Disease Autoimmunity in Children with Type 1 Diabetes. J Pediatr. 2016 Feb;169:44-8.e1. PubMed PMID: 26561381

Uusitalo U, Liu X, Yang J, Aronsson CA, Hummel S, Butterworth M, Lernmark Å, Rewers M, Hagopian W, She JX, Simell O, Toppari J, Ziegler AG, Akolkar B, Krischer J, Norris JM, Virtanen SM. Association of Early Exposure of Probiotics and Islet Autoimmunity in the TEDDY Study. JAMA Pediatr. 2016 Jan;170(1):20-8. PubMed PMID: 26552054

Frohnert BI, Rewers MJ. Metabolomics in childhood diabetes. Pediatr Diabetes. 2016 Feb;17(1):3-14. PubMed PMID: 26420304

Gesualdo PD, Bautista KA, Waugh KC, Yu L, Norris JM, Rewers MJ, Baxter J. Feasibility of screening for T1D and celiac disease in a pediatric clinic setting. Pediatr Diabetes. 2016 Sep;17(6):441-8. PubMed PMID: 26251221

Lorenzo C, Hanley AJ, Rewers MJ, Haffner SM. Discriminatory value of alanine aminotransferase for diabetes prediction: the Insulin Resistance Atherosclerosis Study. Diabet Med. 2016 Mar;33(3):348-55. PubMed PMID: 26094705

Yang J, Lynch KF, Uusitalo UM, Foterek K, Hummel S, Silvis K, Aronsson CA, Riikonen A, Rewers M, She JX, Ziegler AG, Simell OG, Toppari J, Hagopian WA, Lernmark Å, Akolkar B, Krischer JP, Norris JM, Virtanen SM, Johnson SB. Factors associated with longitudinal food record compliance in a paediatric cohort study. Public Health Nutr. 2016 Apr;19(5):804-13. PubMed PMID: 26088478

Andrén Aronsson C, Lee HS, Koletzko S, Uusitalo U, Yang J, Virtanen SM, Liu E, Lernmark Å, Norris JM, Agardh D. Effects of Gluten Intake on Risk of Celiac Disease: A Case-Control Study on a Swedish Birth Cohort. Clin Gastroenterol Hepatol. 2016 Mar;14(3):403-409.e3. PubMed PMID: 26453955

Lernmark B, Lynch K, Baxter J, Roth R, Simell T, Smith L, Swartling U, Johnson SB. Participant Experiences in the Environmental Determinants of Diabetes in the Young Study: Common Reasons for Withdrawing. J Diabetes Res. 2016;2016:2720650. PubMed PMID: 26682228

Haghighi M, Johnson SB, Qian X, Lynch KF, Vehik K, Huang S. A Comparison of Rule-based Analysis with Regression Methods in Understanding the Risk Factors for Study Withdrawal in a Pediatric Study. Sci Rep. 2016 Aug 26;6:30828. PubMed PMID: 27561809

Zhao Z, Miao D, Waugh K, Taki I, Dong F, Liu E, Rewers M, Liu Y, Yu L. Higher Sensitivity and Earlier Identification of Celiac Disease Autoimmunity by a Nonradioactive Assay for Transglutaminase Autoantibodies. J Immunol Res. 2016;2016:2904563. PubMed PMID: 28127566

Aronsson CA, Lee HS, Liu E, Uusitalo U, Hummel S, Yang J, Hummel M, Rewers M, She JX, Simell O, Toppari J, Ziegler AG, Krischer J, Virtanen SM, Norris JM, Agardh D, for the TEDDY STUDY GROUP. Age at Gluten Introduction and Risk of Celiac Disease. Pediatrics. 2015 Jan 19. [Epub ahead of print] PubMed PMID: 25601977

Miao D, Steck AK, Zhang L, Guyer KM, Jiang L, Armstrong T, Muller SM, Krischer J, Rewers M, Yu L. Electrochemiluminescence Assays for Insulin and Glutamic Acid Decarboxylase Autoantibodies Improve Prediction of Type 1 Diabetes Risk. Diabetes Technol Ther. 2015 Jan 6. [Epub ahead of print] PubMed PMID: 25562486

Kemppainen KM, Ardissone AN, Davis-Richardson AG, Fagen JR, Gano KA, León-Novelo LG, Vehik K, Casella G, Simell O, Ziegler AG, Rewers MJ, Lernmark Å, Hagopian W, She JX, Krischer JP, Akolkar B, Schatz DA, Atkinson MA, Triplett EW, TEDDY Study Group. Early childhood gut microbiomes show strong geographic differences among subjects at high risk for type 1 diabetes. Diabetes Care. 2015 Feb;38(2):329-32. PubMed PMID: 25519450

Bjornstad P, Maahs DM, Johnson RJ, Rewers M, Snell-Bergeon JK. Estimated insulin sensitivity predicts regression of albuminuria in Type 1 diabetes. Diabet Med. 2015 Feb;32(2):257-61. PubMed PMID: 25303233

Lamb MM, Miller M, Seifert JA, Frederiksen B, Kroehl M, Rewers M, Norris JM. The effect of childhood cow's milk intake and HLA-DR genotype on risk of islet autoimmunity and type 1 diabetes: The Diabetes Autoimmunity Study in the Young. Pediatr Diabetes. 2015 Feb;16(1):31-8. PubMed PMID: 24444005

Lamb MM, Miller M, Seifert JA, Frederiksen B, Kroehl M, Rewers M, Norris JM. The effect of childhood cow's milk intake and HLA-DR genotype on risk of islet autoimmunity and type 1 diabetes: the Diabetes Autoimmunity Study in the Young. Pediatr Diabetes. 2015 Feb;16(1):31-8. PubMed PMID: 24444005

Bjornstad P, Maahs DM, Johnson RJ, Rewers M, Snell-Bergeon JK. Estimated insulin sensitivity predicts regression of albuminuria in Type 1 diabetes. Diabet Med. 2015 Feb;32(2):257-61. PubMed PMID: 25303233

Duca LM, Maahs DM, Schauer IE, Bergman BC, Nadeau KJ, Bjornstad P, Rewers M, Snell-Bergeon JK. Development and validation of a method to estimate insulin sensitivity in patients with and without type 1 diabetes. J Clin Endocrinol Metab. 2015 Dec 16;:jc20153272. [Epub ahead of print] PubMed PMID: 26672636

Simmons KM, McFann K, Taki I, Liu E, Klingensmith GJ, Rewers MJ, Frohnert BI. Reduced Bone Mineral Density Is Associated with Celiac Disease Autoimmunity in Children with Type 1 Diabetes. J Pediatr. 2015 Nov 7. [Epub ahead of print] PubMed PMID: 26561381

Frohnert BI, Rewers MJ. Metabolomics in childhood diabetes. Pediatr Diabetes. 2015 Sep 30. [Epub ahead of print] PubMed PMID: 26420304

Gutierrez-Achury J, Romanos J, Bakker SF, Kumar V, de Haas EC, Trynka G, Ricaño-Ponce I, Steck A, Chen WM, Onengut-Gumuscu S, Simsek S, Rewers M, Mulder CJ, Liu E, Rich SS, Wijmenga C. Contrasting the Genetic Background of Type 1 Diabetes and Celiac Disease Autoimmunity. Diabetes Care. 2015 Oct;38 Suppl 2:S37-44. PubMed PMID: 26405070

Insel RA, Dunne JL, Atkinson MA, Chiang JL, Dabelea D, Gottlieb PA, Greenbaum CJ, Herold KC, Krischer JP, Lernmark Å, Ratner RE, Rewers MJ, Schatz DA, Skyler JS, Sosenko JM, Ziegler AG. Staging presymptomatic type 1 diabetes: a scientific statement of JDRF, the Endocrine Society, and the American Diabetes Association. Diabetes Care. 2015 Oct;38(10):1964-74. PubMed PMID: 26404926

Lorenzo C, Hanley AJ, Rewers MJ, Festa A, Haffner SM. Lipoprotein heterogeneity may help to detect individuals with insulin resistance. Diabetologia. 2015 Dec;58(12):2765-73. PubMed PMID: 26341113

Chan CL, Taki I, Dong F, Hoffman M, Norris JM, Klingensmith G, Rewers MJ, Steck AK. Comparison of Metabolic Outcomes in Children Diagnosed with Type 1 Diabetes Through Research Screening (Diabetes Autoimmunity Study in the Young [DAISY]) Versus in the Community. Diabetes Technol Ther. 2015 Sep;17(9):649-56. PubMed PMID: 26317880

Gesualdo PD, Bautista KA, Waugh KC, Yu L, Norris JM, Rewers MJ, Baxter J. Feasibility of screening for T1D and celiac disease in a pediatric clinic setting. Pediatr Diabetes. 2015 Aug 6. [Epub ahead of print] PubMed PMID: 26251221

Bjornstad P, Eckel RH, Pyle L, Rewers M, Maahs DM, Snell-Bergeon JK. Relation of Combined Non-High-Density Lipoprotein Cholesterol and Apolipoprotein B With Atherosclerosis in Adults With Type 1 Diabetes Mellitus. Am J Cardiol. 2015 Oct 1;116(7):1057-62. PubMed PMID: 26251001

Shellman YG, Lambert KA, Brauweiler A, Fain P, Spritz RA, Martini M, Janssen KP, Box NF, Terzian T, Rewers M, Horvath A, Stratakis CA, Robinson WA, Robinson SE, Norris DA, Artinger KB, Pacheco TR. SASH1 Is Involved in an Autosomal Dominant Lentiginous Phenotype. J Invest Dermatol. 2015 Dec;135(12):3192-4. PubMed PMID: 26203640

Groves DW, Krantz MJ, Hokanson JE, Johnson LR, Eckel RH, Kinney GL, Rewers M, Snell-Bergeon JK, Alman AC. Comparison of Frequency and Duration of Periodontal Disease With Progression of Coronary Artery Calcium in Patients With and Without Type 1 Diabetes Mellitus. Am J Cardiol. 2015 Sep 15;116(6):833-7. PubMed PMID: 26189036

Beyerlein A, Liu X, Uusitalo UM, Harsunen M, Norris JM, Foterek K, Virtanen SM, Rewers MJ, She JX, Simell O, Lernmark Å, Hagopian W, Akolkar B, Ziegler AG, Krischer JP, Hummel S. Dietary intake of soluble fiber and risk of islet autoimmunity by 5 y of age: results from the TEDDY study. Am J Clin Nutr. 2015 Aug;102(2):345-52. PubMed PMID: 26156735

Lorenzo C, Hanley AJ, Rewers MJ, Haffner SM. Discriminatory value of alanine aminotransferase for diabetes prediction: the Insulin Resistance Atherosclerosis Study. Diabet Med. 2015 Jun 10. [Epub ahead of print] PubMed PMID: 26094705

Yang J, Lynch KF, Uusitalo UM, Foterek K, Hummel S, Silvis K, Andrén Aronsson C, Riikonen A, Rewers M, She JX, Ziegler AG, Simell OG, Toppari J, Hagopian WA, Lernmark Å, Akolkar B, Krischer JP, Norris JM, Virtanen SM, Johnson SB. Factors associated with longitudinal food record compliance in a paediatric cohort study. Public Health Nutr. 2015 Jun 19;:1-10. [Epub ahead of print] PubMed PMID: 26088478

Frederiksen BN, Seifert J, Kroehl M, Lamb MM, Milne GL, Rewers M, Norris JM. Timing of solid food introduction is associated with urinary F2-isoprostane concentrations in childhood. Pediatr Res. 2015 Oct;78(4):451-6. PubMed PMID: 26083762

Bjornstad P, Cherney DZ, Snell-Bergeon JK, Pyle L, Rewers M, Johnson RJ, Maahs DM. Rapid GFR decline is associated with renal hyperfiltration and impaired GFR in adults with Type 1 diabetes. Nephrol Dial Transplant. 2015 Oct;30(10):1706-11. PubMed PMID: 26050268

Lamb MM, Frederiksen B, Seifert JA, Kroehl M, Rewers M, Norris JM. Sugar intake is associated with progression from islet autoimmunity to type 1 diabetes: the Diabetes Autoimmunity Study in the Young. Diabetologia. 2015 Sep;58(9):2027-34. PubMed PMID: 26048237

Hadley D, Hagopian W, Liu E, She JX, Simell O, Akolkar B, Ziegler AG, Rewers M, Krischer JP, Chen WM, Onengut-Gumuscu S, Bugawan TL, Rich SS, Erlich H, Agardh D. HLA-DPB1*04:01 Protects Genetically Susceptible Children from Celiac Disease Autoimmunity in the TEDDY Study. Am J Gastroenterol. 2015 Jun;110(6):915-20. PubMed PMID: 26010309

Rewers A, Dong F, Slover RH, Klingensmith GJ, Rewers M. Incidence of diabetic ketoacidosis at diagnosis of type 1 diabetes in Colorado youth, 1998-2012. JAMA. 2015 Apr 21;313(15):1570-2. PubMed PMID: 25898057

Lönnrot M, Lynch K, Larsson HE, Lernmark Å, Rewers M, Hagopian W, She JX, Simell O, Ziegler AG, Akolkar B, Krischer J, Hyöty H. A method for reporting and classifying acute infectious diseases in a prospective study of young children: TEDDY. BMC Pediatr. 2015 Mar 20;15:24. PubMed PMID: 25884839

Frederiksen BN, Kroehl M, Barón A, Lamb MM, Crume TL, Sontag MK, Rewers M, Norris JM. Assessing age-related etiologic heterogeneity in the onset of islet autoimmunity. Biomed Res Int. 2015;2015:708289. PubMed PMID: 25883970

Hall K, Frederiksen B, Rewers M, Norris JM. Daycare attendance, breastfeeding, and the development of type 1 diabetes: the diabetes autoimmunity study in the young. Biomed Res Int. 2015;2015:203947. PubMed PMID: 25883944

Nakayama M, McDaniel K, Fitzgerald-Miller L, Kiekhaefer C, Snell-Bergeon JK, Davidson HW, Rewers M, Yu L, Gottlieb P, Kappler JW, Michels A. Regulatory vs. inflammatory cytokine T-cell responses to mutated insulin peptides in healthy and type 1 diabetic subjects. Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4429-34. PubMed PMID: 25831495

Steck AK, Dong F, Taki I, Hoffman M, Klingensmith GJ, Rewers MJ. Response to comment on Steck et al. Early hyperglycemia detected by continuous glucose monitoring in children at risk for type 1 diabetes. Diabetes care 2014;37:2031-2033. Diabetes Care. 2015 Mar;38(3):e48. PubMed PMID: 25715429

Steck AK, Vehik K, Bonifacio E, Lernmark A, Ziegler AG, Hagopian WA, She J, Simell O, Akolkar B, Krischer J, Schatz D, Rewers MJ. Predictors of Progression From the Appearance of Islet Autoantibodies to Early Childhood Diabetes: The Environmental Determinants of Diabetes in the Young (TEDDY). Diabetes Care. 2015 May;38(5):808-13. PubMed PMID: 25665818

Krischer JP, Lynch KF, Schatz DA, Ilonen J, Lernmark Å, Hagopian WA, Rewers MJ, She JX, Simell OG, Toppari J, Ziegler AG, Akolkar B, Bonifacio E. The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study. Diabetologia. 2015 May;58(5):980-7. PubMed PMID: 25660258

Aronsson CA, Lee HS, Liu E, Uusitalo U, Hummel S, Yang J, Hummel M, Rewers M, She JX, Simell O, Toppari J, Ziegler AG, Krischer J, Virtanen SM, Norris JM, Agardh D. Age at gluten introduction and risk of celiac disease. Pediatrics. 2015 Feb;135(2):239-45. PubMed PMID: 25601977

Miao D, Steck AK, Zhang L, Guyer KM, Jiang L, Armstrong T, Muller SM, Krischer J, Rewers M, Yu L. Electrochemiluminescence assays for insulin and glutamic acid decarboxylase autoantibodies improve prediction of type 1 diabetes risk. Diabetes Technol Ther. 2015 Feb;17(2):119-27. PubMed PMID: 25562486

Kemppainen KM, Ardissone AN, Davis-Richardson AG, Fagen JR, Gano KA, León-Novelo LG, Vehik K, Casella G, Simell O, Ziegler AG, Rewers MJ, Lernmark Å, Hagopian W, She JX, Krischer JP, Akolkar B, Schatz DA, Atkinson MA, Triplett EW. Early childhood gut microbiomes show strong geographic differences among subjects at high risk for type 1 diabetes. Diabetes Care. 2015 Feb;38(2):329-32. PubMed PMID: 25519450

Törn C, Hadley D, Lee HS, Hagopian W, Lernmark Å, Simell O, Rewers M, Ziegler A, Schatz D, Akolkar B, Onengut-Gumuscu S, Chen WM, Toppari J, Mykkänen J, Ilonen J, Rich SS, She JX, Steck AK, Krischer J. Role of Type 1 Diabetes-Associated SNPs on Risk of Autoantibody Positivity in the TEDDY Study. Diabetes. 2015 May;64(5):1818-29. PubMed PMID: 25422107

Roth R, Lynch K, Lernmark B, Baxter J, Simell T, Smith L, Swartling U, Ziegler AG, Johnson SB. Maternal anxiety about a child's diabetes risk in the TEDDY study: the potential role of life stress, postpartum depression, and risk perception. Pediatr Diabetes. 2015 Jun;16(4):287-98. PubMed PMID: 25082392

Willi SM, Miller KM, DiMeglio LA, Klingensmith GJ, Simmons JH, Tamborlane WV, Nadeau KJ, Kittelsrud JM, Huckfeldt P, Beck RW, Lipman TH. Racial-ethnic disparities in management and outcomes among children with type 1 diabetes. Pediatrics. 2015 Mar;135(3):424-34. PubMed PMID: 25687140

Agardh D, Lee HS, Kurppa K, Simell V, Aronsson CA, Jörneus O, Hummel M, Liu E, Koletzko S. Clinical features of celiac disease: a prospective birth cohort. Pediatrics. 2015 Apr;135(4):627-34. PubMed PMID: 25733751

DuBose SN, Hermann JM, Tamborlane WV, Beck RW, Dost A, DiMeglio LA, Schwab KO, Holl RW, Hofer SE, Maahs DM. Obesity in Youth with Type 1 Diabetes in Germany, Austria, and the United States. J Pediatr. 2015 Sep;167(3):627-32.e1-4. PubMed PMID: 26164381

Lorenzo C, Hanley AJ, Rewers MJ, Haffner SM. Disproportionately elevated proinsulinemia is observed at modestly elevated glucose levels within the normoglycemic range. Acta Diabetol. 2014 Feb 15. [Epub ahead of print] PubMed PMID: 24532116

Lamb MM, Miller M, Seifert JA, Frederiksen B, Kroehl M, Rewers M, Norris JM. The effect of childhood cow's milk intake and HLA-DR genotype on risk of islet autoimmunity and type 1 diabetes: The Diabetes Autoimmunity Study in the Young. Pediatr Diabetes. 2014 Jan 20. [Epub ahead of print] PubMed PMID: 24444005

Norris JM, Kroehl M, Fingerlin TE, Frederiksen BN, Seifert J, Wong R, Clare-Salzler M, Rewers M. Erythrocyte membrane docosapentaenoic acid levels are associated with islet autoimmunity: the Diabetes Autoimmunity Study in the Young. Diabetologia. 2014 Feb;57(2):295-304. PubMed PMID: 24240437

Alman AC, Maahs DM, Rewers MJ, Snell-Bergeon JK. Ideal cardiovascular health and the prevalence and progression of coronary artery calcification in adults with and without type 1 diabetes. Diabetes Care. 2014 Feb;37(2):521-8. PubMed PMID: 24130360

Bjornstad P, Maahs DM, Wadwa RP, Pyle L, Rewers M, Eckel RH, Snell-Bergeon JK. Plasma triglycerides predict incident albuminuria and progression of coronary artery calcification in adults with type 1 diabetes: The Coronary Artery Calcification in Type 1 Diabetes Study. J Clin Lipidol. 2014 Nov-Dec;8(6):576-83. PubMed PMID: 25499940

Törn C, Hadley D, Lee HS, Hagopian W, Lernmark A, Simell O, Rewers M, Ziegler A, Schatz D, Akolkar B, Onengut-Gumuscu S, Chen WM, Toppari J, Mykkänen J, Ilonen J, Rich SS, She JX, Steck AK, Krischer J, the TEDDY Study Group. Role of Type 1 diabetes associated SNPs on risk of autoantibody positivity in the TEDDY Study. Diabetes. 2014 Nov 24. [Epub ahead of print] PubMed PMID: 25422107

Santaren ID, Watkins SM, Liese AD, Wagenknecht LE, Rewers MJ, Haffner SM, Lorenzo C, Hanley AJ. Serum pentadecanoic acid (15:0), a short-term marker of dairy food intake, is inversely associated with incident type 2 diabetes and its underlying disorders. Am J Clin Nutr. 2014 Dec;100(6):1532-40. PubMed PMID: 25411288

Bjornstad P, Maahs DM, Rewers M, Johnson RJ, Snell-Bergeon JK. ABC goal achievement predicts microvascular but not macrovascular complications over 6-years in adults with type 1 diabetes: the Coronary Artery Calcification in Type 1 Diabetes Study. J Diabetes Complications. 2014 Nov-Dec;28(6):762-6. PubMed PMID: 25270733

Soedamah-Muthu SS, Vergouwe Y, Costacou T, Miller RG, Zgibor J, Chaturvedi N, Snell-Bergeon JK, Maahs DM, Rewers M, Forsblom C, Harjutsalo V, Groop PH, Fuller JH, Moons KG, Orchard TJ. Predicting major outcomes in type 1 diabetes: a model development and validation study. Diabetologia. 2014 Nov;57(11):2304-14. PubMed PMID: 25186291

Rewers MJ, Pillay K, de Beaufort C, Craig ME, Hanas R, Acerini CL, Maahs DM. Assessment and monitoring of glycemic control in children and adolescents with diabetes. Pediatr Diabetes. 2014 Sep;15 Suppl 20:102-14. PubMed PMID: 25182311

Steck AK, Dong F, Wong R, Fouts A, Liu E, Romanos J, Wijmenga C, Norris JM, Rewers MJ. Improving prediction of type 1 diabetes by testing non-HLA genetic variants in addition to HLA markers. Pediatr Diabetes. 2014 Aug;15(5):355-62. PubMed PMID: 25075402

Liu E, Lee HS, Aronsson CA, Hagopian WA, Koletzko S, Rewers MJ, Eisenbarth GS, Bingley PJ, Bonifacio E, Simell V, Agardh D, TEDDY Study Group. Risk of pediatric celiac disease according to HLA haplotype and country. N Engl J Med. 2014 Jul 3;371(1):42-9. PubMed PMID: 24988556

Majidi S, Wadwa RP, Bishop FK, Klingensmith GJ, Rewers M, McFann K, Maahs DM. The effect of insurance status and parental education on glycemic control and cardiovascular disease risk profile in youth with Type 1 Diabetes. J Diabetes Metab Disord. 2014;13:59. PubMed PMID: 24955334

Bjornstad P, Maahs DM, Rivard CJ, Pyle L, Rewers M, Johnson RJ, Snell-Bergeon JK. Serum uric acid predicts vascular complications in adults with type 1 diabetes: the coronary artery calcification in type 1 diabetes study. Acta Diabetol. 2014 Oct;51(5):783-91. PubMed PMID: 24929955

Alman AC, Hokanson JE, Kinney GL, Maahs DM, Rewers MJ, Snell-Bergeon JK. Is low CACs really different from zero…: a report from the CACTI study. JACC Cardiovasc Imaging. 2014 Jun;7(6):632-3. PubMed PMID: 24925332

Steck AK, Dong F, Taki I, Hoffman M, Klingensmith GJ, Rewers MJ. Early hyperglycemia detected by continuous glucose monitoring in children at risk for type 1 diabetes. Diabetes Care. 2014 Jul;37(7):2031-3. PubMed PMID: 24784826

Bjornstad P, McQueen RB, Snell-Bergeon JK, Cherney D, Pyle L, Perkins B, Rewers M, Maahs DM. Fasting blood glucose--a missing variable for GFR-estimation in type 1 diabetes?. PLoS One. 2014;9(4):e96264. PubMed PMID: 24781861

Chobot A, Wenzlau J, Bak-Drabik K, Kwiecien J, Polanska J, Rewers M. ATP4A autoimmunity and Helicobacter pylori infection in children with type 1 diabetes. Clin Exp Immunol. 2014 Sep;177(3):598-602. PubMed PMID: 24773566

Lorenzo C, Hanley AJ, Rewers MJ, Haffner SM. Calcium and phosphate concentrations and future development of type 2 diabetes: the Insulin Resistance Atherosclerosis Study. Diabetologia. 2014 Jul;57(7):1366-74. PubMed PMID: 24763850

Yang J, Lernmark A, Uusitalo UM, Lynch KF, Veijola R, Winkler C, Larsson HE, Rewers M, She JX, Ziegler AG, Simell OG, Hagopian WA, Akolkar B, Krischer JP, Vehik K, TEDDY Study Group. Prevalence of obesity was related to HLA-DQ in 2-4-year-old children at genetic risk for type 1 diabetes. Int J Obes (Lond). 2014 Dec;38(12):1491-6. PubMed PMID: 24694666

Bjornstad P, Paul Wadwa R, Sirota JC, Snell-Bergeon JK, McFann K, Rewers M, Rivard CJ, Jalal D, Chonchol MB, Johnson RJ, Maahs DM. Serum uric acid and hypertension in adults: a paradoxical relationship in type 1 diabetes. J Clin Hypertens (Greenwich). 2014 Apr;16(4):283-8. PubMed PMID: 24667019

Jin Y, Sharma A, Bai S, Davis C, Liu H, Hopkins D, Barriga K, Rewers M, She JX. Risk of type 1 diabetes progression in islet autoantibody-positive children can be further stratified using expression patterns of multiple genes implicated in peripheral blood lymphocyte activation and function. Diabetes. 2014 Jul;63(7):2506-15. PubMed PMID: 24595351

Lorenzo C, Hanley AJ, Rewers MJ, Haffner SM. Disproportionately elevated proinsulinemia is observed at modestly elevated glucose levels within the normoglycemic range. Acta Diabetol. 2014 Aug;51(4):617-23. PubMed PMID: 24532116

Bjornstad P, Snell-Bergeon JK, McFann K, Wadwa RP, Rewers M, Rivard CJ, Jalal D, Chonchol MB, Johnson RJ, Maahs DM. Serum uric acid and insulin sensitivity in adolescents and adults with and without type 1 diabetes. J Diabetes Complications. 2014 May-Jun;28(3):298-304. PubMed PMID: 24461546

Lee HS, Burkhardt BR, McLeod W, Smith S, Eberhard C, Lynch K, Hadley D, Rewers M, Simell O, She JX, Hagopian B, Lernmark A, Akolkar B, Ziegler AG, Krischer JP, TEDDY study group. Biomarker discovery study design for type 1 diabetes in The Environmental Determinants of Diabetes in the Young (TEDDY) study. Diabetes Metab Res Rev. 2014 Jul;30(5):424-34. PubMed PMID: 24339168

Norris JM, Kroehl M, Fingerlin TE, Frederiksen BN, Seifert J, Wong R, Clare-Salzler M, Rewers M. Erythrocyte membrane docosapentaenoic acid levels are associated with islet autoimmunity: the Diabetes Autoimmunity Study in the Young. Diabetologia. 2014 Feb;57(2):295-304. PubMed PMID: 24240437

Gottlieb PA, Delong T, Baker RL, Fitzgerald-Miller L, Wagner R, Cook G, Rewers MR, Michels A, Haskins K. Chromogranin A is a T cell antigen in human type 1 diabetes. J Autoimmun. 2014 May;50:38-41. PubMed PMID: 24239002

Alman AC, Maahs DM, Rewers MJ, Snell-Bergeon JK. Ideal cardiovascular health and the prevalence and progression of coronary artery calcification in adults with and without type 1 diabetes. Diabetes Care. 2014 Feb;37(2):521-8. PubMed PMID: 24130360

Goodarzi MO, Langefeld CD, Xiang AH, Chen YD, Guo X, Hanley AJ, Raffel LJ, Kandeel F, Nadler JL, Buchanan TA, Norris JM, Fingerlin TE, Lorenzo C, Rewers MJ, Haffner SM, Bowden DW, Rich SS, Bergman RN, Rotter JI, Watanabe RM, Wagenknecht LE. Insulin sensitivity and insulin clearance are heritable and have strong genetic correlation in Mexican Americans. Obesity (Silver Spring). 2014 Apr;22(4):1157-64. PubMed PMID: 24124113

Elding Larsson H, Vehik K, Gesualdo P, Akolkar B, Hagopian W, Krischer J, Lernmark Å, Rewers M, Simell O, She JX, Ziegler A, Haller MJ, TEDDY Study Group. Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease. Pediatr Diabetes. 2014 Mar;15(2):118-26. PubMed PMID: 24034790

Lee CT, Liese AD, Lorenzo C, Wagenknecht LE, Haffner SM, Rewers MJ, Hanley AJ. Egg consumption and insulin metabolism in the Insulin Resistance Atherosclerosis Study (IRAS). Public Health Nutr. 2014 Jul;17(7):1595-602. PubMed PMID: 23777633

Romanos J, Rosén A, Kumar V, Trynka G, Franke L, Szperl A, Gutierrez-Achury J, van Diemen CC, Kanninga R, Jankipersadsing SA, Steck A, Eisenbarth G, van Heel DA, Cukrowska B, Bruno V, Mazzilli MC, Núñez C, Bilbao JR, Mearin ML, Barisani D, Rewers M, Norris JM, Ivarsson A, Boezen HM, Liu E, Wijmenga C, PreventCD Group. Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants. Gut. 2014 Mar;63(3):415-22. PubMed PMID: 23704318

Zhang Q, Fillmore TL, Schepmoes AA, Clauss TR, Gritsenko MA, Mueller PW, Rewers M, Atkinson MA, Smith RD, Metz TO. Serum proteomics reveals systemic dysregulation of innate immunity in type 1 diabetes. J Exp Med. 2013 Jan 14;210(1):191-203. PubMed PMID: 23277452

Narwaney KJ, Glanz JM, Norris JM, Fingerlin TE, Hokanson JE, Rewers M, Hambidge SJ. Association of HLA class II genes with clinical hyporesponsiveness to trivalent inactivated influenza vaccine in children. Vaccine. 2013 Feb 4;31(7):1123-8. PubMed PMID: 23261040

Bergman BC, Howard D, Schauer IE, Maahs DM, Snell-Bergeon JK, Clement TW, Eckel RH, Perreault L, Rewers M. The importance of palmitoleic acid to adipocyte insulin resistance and whole-body insulin sensitivity in type 1 diabetes. J Clin Endocrinol Metab. 2013 Jan;98(1):E40-50. PubMed PMID: 23150678

Lee CC, Lorenzo C, Haffner SM, Wagenknecht LE, Festa A, Goodarzi MO, Stefanovski D, Olson NC, Norris JM, Rewers MJ, Hanley AJ. The association of inflammatory and fibrinolytic proteins with 5 year change in insulin clearance: the Insulin Resistance Atherosclerosis Study (IRAS). Diabetologia. 2013 Jan;56(1):112-20. PubMed PMID: 23052060

Frederiksen B, Liu E, Romanos J, Steck AK, Yin X, Kroehl M, Fingerlin TE, Erlich H, Eisenbarth GS, Rewers M, Norris JM. Investigation of the vitamin D receptor gene (VDR) and its interaction with protein tyrosine phosphatase, non-receptor type 2 gene (PTPN2) on risk of islet autoimmunity and type 1 diabetes: the Diabetes Autoimmunity Study in the Young (DAISY). J Steroid Biochem Mol Biol. 2013 Jan;133:51-7. PubMed PMID: 22960018

Lorenzo C, Hanley AJ, Wagenknecht LE, Rewers MJ, Stefanovski D, Goodarzi MO, Haffner SM. Relationship of insulin sensitivity, insulin secretion, and adiposity with insulin clearance in a multiethnic population: the insulin Resistance Atherosclerosis study. Diabetes Care. 2013 Jan;36(1):101-3. PubMed PMID: 22933441

Bjornstad P, Snell-Bergeon JK, McFann K, Wadwa RP, Rewers M, Rivard CJ, Jalal D, Chonchol MB, Johnson RJ, Maahs DM. Serum uric acid and insulin sensitivity in adolescents and adults with and without type 1 diabetes. J Diabetes Complications. 2013 Dec 27. [Epub ahead of print] PubMed PMID: 24461546

Frederiksen BN, Steck AK, Kroehl M, Lamb MM, Wong R, Rewers M, Norris JM. Evidence of stage- and age-related heterogeneity of non-HLA SNPs and risk of islet autoimmunity and type 1 diabetes: the diabetes autoimmunity study in the young. Clin Dev Immunol. 2013;2013:417657. PubMed PMID: 24367383

Lee HS, Burkhardt BR, McLeod W, Smith S, Eberhard C, Lynch K, Hadley D, Rewers M, Simell O, She JX, Hagopian B, Lernmark A, Akolkar B, Ziegler AG, Krischer JP, the TEDDY Study Group. Biomarker discovery study design for type 1 diabetes in The Environmental Determinants of Diabetes in the Young (TEDDY) study. Diabetes Metab Res Rev. 2013 Dec 15. [Epub ahead of print] PubMed PMID: 24339168

Gottlieb PA, Delong T, Baker RL, Fitzgerald-Miller L, Wagner R, Cook G, Rewers MR, Michels A, Haskins K. Chromogranin A is a T cell antigen in human type 1 diabetes. J Autoimmun. 2013 Nov 12. [Epub ahead of print] PubMed PMID: 24239002

Goodarzi MO, Langefeld CD, Xiang AH, Chen YD, Guo X, Hanley AJ, Raffel LJ, Kandeel F, Buchanan TA, Norris JM, Fingerlin TE, Lorenzo C, Rewers MJ, Haffner SM, Bowden DW, Rich SS, Bergman RN, Rotter JI, Watanabe RM, Wagenknecht LE. Insulin Sensitivity and Insulin Clearance are Heritable and Have Strong Genetic Correlation in Mexican Americans. Obesity (Silver Spring). 2013 Oct 9. [Epub ahead of print] PubMed PMID: 24124113

Elding Larsson H, Vehik K, Gesualdo P, Akolkar B, Hagopian W, Krischer J, Lernmark A, Rewers M, Simell O, She JX, Ziegler A, Haller MJ, the TEDDY Study Group. Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease. Pediatr Diabetes. 2013 Aug 27. [Epub ahead of print] PubMed PMID: 24034790

Bjornstad P, Snell-Bergeon JK, Rewers M, Jalal D, Chonchol MB, Johnson RJ, Maahs DM. Early diabetic nephropathy: a complication of reduced insulin sensitivity in type 1 diabetes. Diabetes Care. 2013 Nov;36(11):3678-83. PubMed PMID: 24026551

Frederiksen BN, Kroehl M, Fingerlin TE, Wong R, Steck AK, Rewers M, Norris JM. Association between vitamin D metabolism gene polymorphisms and risk of islet autoimmunity and progression to type 1 diabetes: the diabetes autoimmunity study in the young (DAISY). J Clin Endocrinol Metab. 2013 Nov;98(11):E1845-51. PubMed PMID: 23979957

Miao D, Guyer KM, Dong F, Jiang L, Steck AK, Rewers M, Eisenbarth GS, Yu L. GAD65 autoantibodies detected by electrochemiluminescence assay identify high risk for type 1 diabetes. Diabetes. 2013 Dec;62(12):4174-8. PubMed PMID: 23974918

Frederiksen B, Kroehl M, Lamb MM, Seifert J, Barriga K, Eisenbarth GS, Rewers M, Norris JM. Infant exposures and development of type 1 diabetes mellitus: The Diabetes Autoimmunity Study in the Young (DAISY). JAMA Pediatr. 2013 Sep;167(9):808-15. PubMed PMID: 23836309

Maahs DM, Jalal D, Chonchol M, Johnson RJ, Rewers M, Snell-Bergeon JK. Impaired renal function further increases odds of 6-year coronary artery calcification progression in adults with type 1 diabetes: the CACTI study. Diabetes Care. 2013 Sep;36(9):2607-14. PubMed PMID: 23835686

Rewers M. The next big idea. Diabetes Technol Ther. 2013 Jun;15 Suppl 2:S2-29-S2-36. PubMed PMID: 23786296

Ziegler AG, Rewers M, Simell O, Simell T, Lempainen J, Steck A, Winkler C, Ilonen J, Veijola R, Knip M, Bonifacio E, Eisenbarth GS. Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children. JAMA. 2013 Jun 19;309(23):2473-9. PubMed PMID: 23780460

Lee CT, Liese AD, Lorenzo C, Wagenknecht LE, Haffner SM, Rewers MJ, Hanley AJ. Egg consumption and insulin metabolism in the Insulin Resistance Atherosclerosis Study (IRAS). Public Health Nutr. 2013 Jun 19;:1-8. [Epub ahead of print] PubMed PMID: 23777633

Lorenzo C, Hanley AJ, Wagenknecht LE, Rewers MJ, Stefanovski D, Goodarzi MO, Haffner SM. Relationship of insulin sensitivity, insulin secretion, and adiposity with insulin clearance in a multiethnic population: the insulin Resistance Atherosclerosis study. Diabetes Care. 2013 Jan;36(1):101-3. PubMed PMID: 22933441

Frederiksen B, Liu E, Romanos J, Steck AK, Yin X, Kroehl M, Fingerlin TE, Erlich H, Eisenbarth GS, Rewers M, Norris JM. Investigation of the vitamin D receptor gene (VDR) and its interaction with protein tyrosine phosphatase, non-receptor type 2 gene (PTPN2) on risk of islet autoimmunity and type 1 diabetes: the Diabetes Autoimmunity Study in the Young (DAISY). J Steroid Biochem Mol Biol. 2013 Jan;133:51-7. PubMed PMID: 22960018

Lee CC, Lorenzo C, Haffner SM, Wagenknecht LE, Festa A, Goodarzi MO, Stefanovski D, Olson NC, Norris JM, Rewers MJ, Hanley AJ. The association of inflammatory and fibrinolytic proteins with 5 year change in insulin clearance: the Insulin Resistance Atherosclerosis Study (IRAS). Diabetologia. 2013 Jan;56(1):112-20. PubMed PMID: 23052060

Bergman BC, Howard D, Schauer IE, Maahs DM, Snell-Bergeon JK, Clement TW, Eckel RH, Perreault L, Rewers M. The importance of palmitoleic acid to adipocyte insulin resistance and whole-body insulin sensitivity in type 1 diabetes. J Clin Endocrinol Metab. 2013 Jan;98(1):E40-50. PubMed PMID: 23150678

Lee CC, Lorenzo C, Haffner SM, Wagenknecht LE, Goodarzi MO, Stefanovski D, Norris JM, Rewers MJ, Hanley AJ. Components of metabolic syndrome and 5-year change in insulin clearance - the Insulin Resistance Atherosclerosis Study. Diabetes Obes Metab. 2013 May;15(5):441-7. PubMed PMID: 23216702

Narwaney KJ, Glanz JM, Norris JM, Fingerlin TE, Hokanson JE, Rewers M, Hambidge SJ. Association of HLA class II genes with clinical hyporesponsiveness to trivalent inactivated influenza vaccine in children. Vaccine. 2013 Feb 4;31(7):1123-8. PubMed PMID: 23261040

Zhang Q, Fillmore TL, Schepmoes AA, Clauss TR, Gritsenko MA, Mueller PW, Rewers M, Atkinson MA, Smith RD, Metz TO. Serum proteomics reveals systemic dysregulation of innate immunity in type 1 diabetes. J Exp Med. 2013 Jan 14;210(1):191-203. PubMed PMID: 23277452

Alman AC, Kinney GL, Tracy RP, Maahs DM, Hokanson JE, Rewers MJ, Snell-Bergeon JK. Prospective association between inflammatory markers and progression of coronary artery calcification in adults with and without type 1 diabetes. Diabetes Care. 2013 Jul;36(7):1967-73. PubMed PMID: 23340891

Lorenzo C, Hanley AJ, Rewers MJ, Haffner SM. The association of alanine aminotransferase within the normal and mildly elevated range with lipoproteins and apolipoproteins: the Insulin Resistance Atherosclerosis Study. Diabetologia. 2013 Apr;56(4):746-57. PubMed PMID: 23344727

Nokoff N, Rewers M. Pathogenesis of type 1 diabetes: lessons from natural history studies of high-risk individuals. Ann N Y Acad Sci. 2013 Apr;1281:1-15. PubMed PMID: 23360422

Lorenzo C, Hartnett S, Hanley AJ, Rewers MJ, Wagenknecht LE, Karter AJ, Haffner SM. Impaired fasting glucose and impaired glucose tolerance have distinct lipoprotein and apolipoprotein changes: the insulin resistance atherosclerosis study. J Clin Endocrinol Metab. 2013 Apr;98(4):1622-30. PubMed PMID: 23450048

Lamb MM, Simpson MD, Seifert J, Scott FW, Rewers M, Norris JM. The association between IgG4 antibodies to dietary factors, islet autoimmunity and type 1 diabetes: the Diabetes Autoimmunity Study in the Young. PLoS One. 2013;8(2):e57936. PubMed PMID: 23469110

Levy NS, Vardi M, Blum S, Miller-Lotan R, Afinbinder Y, Cleary PA, Paterson AD, Bharaj B, Snell-Bergeon JK, Rewers MJ, Lache O, Levy AP. An enzyme linked immunosorbent assay (ELISA) for the determination of the human haptoglobin phenotype. Clin Chem Lab Med. 2013 Aug;51(8):1615-22. PubMed PMID: 23492570

Lee HS, Briese T, Winkler C, Rewers M, Bonifacio E, Hyoty H, Pflueger M, Simell O, She JX, Hagopian W, Lernmark A, Akolkar B, Krischer JP, Ziegler AG, TEDDY study group. Next-generation sequencing for viruses in children with rapid-onset type 1 diabetes. Diabetologia. 2013 Aug;56(8):1705-11. PubMed PMID: 23657799

Vehik K, Fiske SW, Logan CA, Agardh D, Cilio CM, Hagopian W, Simell O, Roivainen M, She JX, Briese T, Oikarinen S, Hyoty H, Ziegler AG, Rewers M, Lernmark A, Akolkar B, Krischer JP, Burkhardt BR, TEDDY Study Group. Methods, quality control and specimen management in an international multicentre investigation of type 1 diabetes: TEDDY. Diabetes Metab Res Rev. 2013 Oct;29(7):557-67. PubMed PMID: 23674484

Lee CC, Lorenzo C, Haffner SM, Wagenknecht LE, Goodarzi MO, Stefanovski D, Norris JM, Rewers MJ, Hanley AJ. Components of metabolic syndrome and 5-year change in insulin clearance - the Insulin Resistance Atherosclerosis Study. Diabetes Obes Metab. 2012 Dec 6. [Epub ahead of print] PubMed PMID: 23216702

Snell-Bergeon JK, Smith J, Dong F, Barón AE, Barriga K, Norris JM, Rewers M. Early childhood infections and the risk of islet autoimmunity: the Diabetes Autoimmunity Study in the Young (DAISY). Diabetes Care. 2012 Dec;35(12):2553-8. PubMed PMID: 23043167

Burbelo PD, Lebovitz EE, Bren KE, Bayat A, Paviol S, Wenzlau JM, Barriga KJ, Rewers M, Harlan DM, Iadarola MJ. Extrapancreatic autoantibody profiles in type I diabetes. PLoS One. 2012;7(9):e45216. PubMed PMID: 23028856

Howson JM, Cooper JD, Smyth DJ, Walker NM, Stevens H, She JX, Eisenbarth GS, Rewers M, Todd JA, Akolkar B, Concannon P, Erlich HA, Julier C, Morahan G, Nerup J, Nierras C, Pociot F, Rich SS, Type 1 Diabetes Genetics Consortium. Evidence of gene-gene interaction and age-at-diagnosis effects in type 1 diabetes. Diabetes. 2012 Nov;61(11):3012-7. PubMed PMID: 22891215

Bishop FK, Wadwa RP, Ellis S, Rewers M, Maahs DM. Lessons learned from a lipid lowering trial in adolescents with type 1 diabetes. Int J Pediatr Endocrinol. 2012 Jul 30;2012(1):24. PubMed PMID: 22846167

Johnson K, Wong R, Barriga KJ, Klingensmith G, Ziegler AG, Rewers MJ, Steck AK. rs11203203 is associated with type 1 diabetes risk in population pre-screened for high-risk HLA-DR,DQ genotypes. Pediatr Diabetes. 2012 Dec;13(8):611-5. PubMed PMID: 22776074

Alkanani AK, Rewers M, Dong F, Waugh K, Gottlieb PA, Zipris D. Dysregulated Toll-like receptor-induced interleukin-1ß and interleukin-6 responses in subjects at risk for the development of type 1 diabetes. Diabetes. 2012 Oct;61(10):2525-33. PubMed PMID: 22751696

Baker P, Fain P, Kahles H, Yu L, Hutton J, Wenzlau J, Rewers M, Badenhoop K, Eisenbarth G. Genetic determinants of 21-hydroxylase autoantibodies amongst patients of the Type 1 Diabetes Genetics Consortium. J Clin Endocrinol Metab. 2012 Aug;97(8):E1573-8. PubMed PMID: 22723331

Vehik K, Cuthbertson D, Boulware D, Beam CA, Rodriguez H, Legault L, Hyytinen M, Rewers MJ, Schatz DA, Krischer JP, TEDDY, TRIGR, Diabetes Prevention Trial–Type 1, and Type 1 Diabetes TrialNet Natural History Study Groups. Performance of HbA1c as an early diagnostic indicator of type 1 diabetes in children and youth. Diabetes Care. 2012 Sep;35(9):1821-5. PubMed PMID: 22699293

Rewers M. Challenges in diagnosing type 1 diabetes in different populations. Diabetes Metab J. 2012 Apr;36(2):90-7. PubMed PMID: 22540044

Nokoff NJ, Rewers M, Cree Green M. The interplay of autoimmunity and insulin resistance in type 1 diabetes. Discov Med. 2012 Feb;13(69):115-22. PubMed PMID: 22369970

Bergman BC, Howard D, Schauer IE, Maahs DM, Snell-Bergeon JK, Eckel RH, Perreault L, Rewers M. Features of hepatic and skeletal muscle insulin resistance unique to type 1 diabetes. J Clin Endocrinol Metab. 2012 May;97(5):1663-72. PubMed PMID: 22362823

Stene LC, Rewers M. Immunology in the clinic review series; focus on type 1 diabetes and viruses: the enterovirus link to type 1 diabetes: critical review of human studies. Clin Exp Immunol. 2012 Apr;168(1):12-23. PubMed PMID: 22385232

Marian Rewers, MD, PhD
Professor, Pediatrics-Barbara Davis Center

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Marian Rewers, MD, PhD Professor, Pediatrics-Barbara Davis Center