ERNEST E MOORE, MD
Distinguished Professor, Surgery-GI, Trauma, and Endocrine Surgery

Website
ernest.moore@dhha.org
Website
ernest.moore@dhha.org
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Medical School:
  • MD, University of Pittsburgh School of Medicine (1972)
Undergraduate School:
  • BS, Allegheny College (PA) (1968)
Internship:
  • University of Vermont Program (1973)
Residency:
  • University of Vermont Program, Surgery (1976)
Languages: English
Department: Surgery-GI, Trauma, and Endocrine Surgery

Professional Titles

  • Director, Surgical Research
  • Distinguished Professor

Recognition & Awards

  • Medallion for Scientific Achievement, American Surgical Association (2019)
  • Distinguished Investigator Award, Shock Society (2017)
  • Lifetime Achievement Award, Society of University Surgeons (2016)
  • Honorary Fellowship, Royal College of of Surgeons in Ireland (2015)
  • Honorary Fellowship, Royal College of Surgeons of Thailand (2015)
  • Lifetime Award, International Association of Trauma and Surgical Intensive Care (2015)
  • Distinguished Investigator Awrd, American College of Critical Care Medicine (2014)
  • Honorary Member, European Society for Trauma and Emergency Surgery (2013)
  • Alpha Omega Alpha Honorary Medical Society, University of Colorado School of Medicine (2012)
  • Honorary Fellowship, The Royal College of Surgeons of Edinburgh (2012)
  • Honorary Member, Brazilian Society of Integrated Trauma Care (2012)
  • Lifetime Achievement Award in Resuscitation, American Heart Association (2012)
  • Master Surgeon (Thoracic Surgery for the Acute Care Surgeon), American Association for the Surgery of Trauma (2011)
  • The Orazio Campione Prize (Acute Care Surgery), World Society of Emergency Surgery (2010)
  • Honorary Fellowship, American College of Emergency Physicians (2009)
  • Scudder Oration, American College of Surgery (2002)
  • Phillip Hench Award, University of Pittsburgh School of Medicine (2001)
  • Florence Sabin Award, University of colorado School of Medicine (2001)
  • The Robert Danis Award, International Society of Surgery (1999)

Publications

  • Podda M, Andersson R, Boermeester M, Coccolini F, Sartelli M, Moore EE, Sugrue M, Abu-Zidan F, Tolonen M, Damaskos D, Kluger Y, Soreide K, Pisanu A, Augustin G, Latifi R, Kelly M, Leppaniemi A, Fraga GP, Ten Broek R, Tan E, Van Goor H, Chiara O, Maier RV, Pata F, De Simone B, Ordoñez CA, Ansaloni L, Catena F, Di Saverio S. Do young patients with high clinical suspicion of appendicitis really need cross sectional imaging? Proceedings from a highly controversial debate among the experts' panel of 2020 WSES Jerusalem Guidelines. J Trauma Acute Care Surg. 2021 Jan 25. [Epub ahead of print] PubMed PMID: 33496553
  • Walsh M, Moore EE, Moore HB, Thomas S, Kwaan HC, Speybroeck J, Marsee M, Bunch CM, Stillson J, Thomas AV, Grisoli A, Aversa J, Fulkerson D, Vande Lune S, Sjeklocha L, Tran QK. Whole Blood, Fixed Ratio, or Goal-Directed Blood Component Therapy for the Initial Resuscitation of Severely Hemorrhaging Trauma Patients: A Narrative Review. J Clin Med. 2021 Jan 17;10(2). PubMed PMID: 33477257
  • Rosen NG, Escobar MA Jr, Brown CV, Moore EE, Sava JA, Peck K, Ciesla DJ, Sperry JL, Rizzo AG, Ley EJ, Brasel KJ, Kozar R, Inaba K, Hoffman-Rosenfeld JL, Notrica DM, Sayrs LW, Nickoles T, Letton RW Jr, Falcone RA Jr, Mitchell IC, Martin MJ. Child Physical Abuse Trauma Evaluation and Management: A Western Trauma Association and Pediatric Trauma Society Critical Decisions Algorithm. J Trauma Acute Care Surg. 2021 Jan 11. [Epub ahead of print] PubMed PMID: 33443985
  • Samuels JM, Sun K, Moore EE, Coleman JR, Fox CJ, Cohen MJ, Sauaia A, MacTaggart JN. Trauma surgeons as the vanguard for safe REBOA implementation - response to letter to the editor. J Trauma Acute Care Surg. 2021 Jan 6;Publish Ahead of Print. [Epub ahead of print] PubMed PMID: 33417409
  • Holcomb JB, Moore EE, Sperry JL, Jansen JO, Schreiber MA, Del Junco DJ, Spinella PC, Sauaia A, Brohi K, Bulger EM, Cap AP, Hess JR, Jenkins D, Lewis RJ, Neal MD, Newgard C, Pati S, Pusateri AE, Rizoli S, Russell RT, Shackelford SA, Stein DM, Steiner ME, Wang H, Ward KR, Young P. Evidence-Based and Clinically Relevant Outcomes for Hemorrhage Control Trauma Trials. Ann Surg. 2021 Mar 1;273(3):395-401. PubMed PMID: 33065652
  • Peck KA, Ley EJ, Brown CV, Moore EE, Sava JA, Ciesla DJ, Sperry JL, Rizzo AG, Rosen NG, Brasel KJ, Kozar R, Inaba K, Martin MJ. Early anticoagulant reversal after trauma: A Western Trauma Association critical decisions algorithm. J Trauma Acute Care Surg. 2021 Feb 1;90(2):331-336. PubMed PMID: 33055578
  • Coleman JR, Carmichael H, Zangara T, Dunn J, Schroeppel TJ, Campion E, Goodman M, Hosokawa P, Sauaia A, Moore EE, Bunn B, Floren M, Ferrigno L. A Stitch in Time Saves Clots: Venous Thromboembolism Chemoprophylaxis in Traumatic Brain Injury. J Surg Res. 2021 Feb;258:289-298. PubMed PMID: 33039638
  • Schwed AC, Wagenaar A, Reppert AE, Gore AV, Pieracci FM, Platnick KB, Lawless RA, Campion EM, Coleman JJ, Cohen MJ, Moore EE, Burlew CC. Trust the FAST: Confirmation that the FAST examination is highly specific for intra-abdominal hemorrhage in over 1,200 patients with pelvic fractures. J Trauma Acute Care Surg. 2021 Jan 1;90(1):137-142. PubMed PMID: 32976327
  • Bedard AF, Mata LV, Dymond C, Moreira F, Dixon J, Schauer SG, Ginde AA, Bebarta V, Moore EE, Mould-Millman NK. A scoping review of worldwide studies evaluating the effects of prehospital time on trauma outcomes. Int J Emerg Med. 2020 Dec 9;13(1):64. PubMed PMID: 33297951
  • Stettler GR, Moore EE, Nunns GR, Kelher M, Banerjee A, Silliman CC. Effects of Blood Components and Whole Blood in a Model of Severe Trauma-Induced Coagulopathy. J Surg Res. 2020 Dec 2;259:55-61. [Epub ahead of print] PubMed PMID: 33278796
  • Vigneshwar NG, Moore HB, Moore EE. Challenges in Acute Care Surgery: Zone II Neck Gun Shot Wound at a Remote Rural Hospital. J Trauma Acute Care Surg. 2020 Nov 20. [Epub ahead of print] PubMed PMID: 33230088
  • Kobayashi L, Coimbra R, Goes AMO Jr, Reva V, Santorelli J, Moore EE, Galante JM, Abu-Zidan F, Peitzman AB, Ordonez CA, Maier RV, Di Saverio S, Ivatury R, De Angelis N, Scalea T, Catena F, Kirkpatrick A, Khokha V, Parry N, Civil I, Leppaniemi A, Chirica M, Pikoulis E, Fraga GP, Chiarugi M, Damaskos D, Cicuttin E, Ceresoli M, De Simone B, Vega-Rivera F, Sartelli M, Biffl W, Ansaloni L, Weber DG, Coccolini F. American Association for the Surgery of Trauma-World Society of Emergency Surgery guidelines on diagnosis and management of abdominal vascular injuries. J Trauma Acute Care Surg. 2020 Dec;89(6):1197-1211. PubMed PMID: 33230049
  • Kobayashi L, Coimbra R, Goes AMO Jr, Reva V, Santorelli J, Moore EE, Galante J, Abu-Zidan F, Peitzman AB, Ordonez C, Maier RV, Di Saverio S, Ivatury R, De Angelis N, Scalea T, Catena F, Kirkpatrick A, Khokha V, Parry N, Civil I, Leppaniemi A, Chirica M, Pikoulis E, Fraga GP, Chiarugi M, Damaskos D, Cicuttin E, Ceresoli M, De Simone B, Vega-Rivera F, Sartelli M, Biffl W, Ansaloni L, Weber DG, Coccolini F. American Association for the Surgery of Trauma-World Society of Emergency Surgery guidelines on diagnosis and management of peripheral vascular injuries. J Trauma Acute Care Surg. 2020 Dec;89(6):1183-1196. PubMed PMID: 33230048
  • Barrett CD, Moore HB, Vigneshwar N, Dhara S, Chandler J, Chapman MP, Sauaia A, Moore EE, Yaffe MB. Plasmin thrombelastography rapidly identifies trauma patients at risk for massive transfusion, mortality, and hyperfibrinolysis: A diagnostic tool to resolve an international debate on tranexamic acid?. J Trauma Acute Care Surg. 2020 Dec;89(6):991-998. PubMed PMID: 33230046
  • Nunns GR, Vigneshwar N, Kelher MR, Stettler GR, Gera L, Reisz JA, D'Alessandro A, Ryon J, Hansen KC, Gamboni F, Moore EE, Peltz ED, Cohen MJ, Jones KL, Sauaia A, Liang X, Banerjee A, Ghasabyan A, Chandler JG, Rodawig S, Jones C, Eitel A, Hom P, Silliman CC. Succinate Activation of SUCNR1 Predisposes Severely Injured Patients to Neutrophil-Mediated ARDS. Ann Surg. 2020 Nov 18. [Epub ahead of print] PubMed PMID: 33214479
  • Vigneshwar NG, Moore EE, Moore HB, Cotton BA, Holcomb JB, Cohen MJ, Sauaia A. Precision medicine: clinical tolerance to hyperfibrinolysis differs by shock and injury severity. Ann Surg. 2020 Nov 17. [Epub ahead of print] PubMed PMID: 33214445
  • Coleman JR, Moore EE, Vintimilla DR, Parry J, Nelson JT, Samuels JM, Sauaia A, Cohen MJ, Burlew CC, Mauffrey C. Association between Young-Burgess pelvic ring injury classification and concomitant injuries requiring urgent intervention. J Clin Orthop Trauma. 2020 Nov-Dec;11(6):1099-1103. PubMed PMID: 33192014
  • Pisano M, Allievi N, Gurusamy K, Borzellino G, Cimbanassi S, Boerna D, Coccolini F, Tufo A, Di Martino M, Leung J, Sartelli M, Ceresoli M, Maier RV, Poiasina E, De Angelis N, Magnone S, Fugazzola P, Paolillo C, Coimbra R, Di Saverio S, De Simone B, Weber DG, Sakakushev BE, Lucianetti A, Kirkpatrick AW, Fraga GP, Wani I, Biffl WL, Chiara O, Abu-Zidan F, Moore EE, Leppäniemi A, Kluger Y, Catena F, Ansaloni L. 2020 World Society of Emergency Surgery updated guidelines for the diagnosis and treatment of acute calculus cholecystitis. World J Emerg Surg. 2020 Nov 5;15(1):61. PubMed PMID: 33153472
  • Brown CVR, Inaba K, Shatz DV, Moore EE, Ciesla D, Sava JA, Alam HB, Brasel K, Vercruysse G, Sperry JL, Rizzo AG, Martin M. Western Trauma Association critical decisions in trauma: airway management in adult trauma patients. Trauma Surg Acute Care Open. 2020;5(1):e000539. PubMed PMID: 33083558
  • Moore LJ, Fox EE, Meyer DE, Wade CE, Podbielski JM, Xu X, Morrison JJ, Scalea T, Fox CJ, Moore EE, Morse BC, Inaba K, Bulger EM, Holcomb JB. Prospective Observational Evaluation of the ER-REBOA Catheter at 6 U.S. Trauma Centers. Ann Surg. 2020 Jun 23. [Epub ahead of print] PubMed PMID: 33064384
  • Moore EE, Liu D, Bown CW, Kresge HA, Gupta DK, Pechman KR, Mendes LA, Davis LT, Gifford KA, Anderson AW, Wang TJ, Landman BA, Hohman TJ, Jefferson AL. Lower cardiac output is associated with neurodegeneration among older adults with normal cognition but not mild cognitive impairment. Brain Imaging Behav. 2020 Oct 10. [Epub ahead of print] PubMed PMID: 33040257
  • Kobayashi L, Coimbra R, Goes AMO Jr, Reva V, Santorelli J, Moore EE, Galante JM, Abu-Zidan F, Peitzman AB, Ordonez CA, Maier RV, Di Saverio S, Ivatury R, De Angelis N, Scalea T, Catena F, Kirkpatrick A, Khokha V, Parry N, Civil I, Leppaniemi A, Chirica M, Pikoulis E, Fraga GP, Chiarugi M, Damaskos D, Cicuttin E, Ceresoli M, De Simone B, Vega-Rivera F, Sartelli M, Biffl W, Ansaloni L, Weber DG, Coccolini F. AAST - WSES Guidelines on Diagnosis and Management of Abdominal Vascular Injuries. J Trauma Acute Care Surg. 2020 Oct 1. [Epub ahead of print] PubMed PMID: 33009336
  • Kobayashi L, Coimbra R, Goes AMO Jr, Reva V, Santorelli J, Moore EE, Galante J, Abu-Zidan F, Peitzman AB, Ordonez C, Maier RV, Di Saverio S, Ivatury R, De Angelis N, Scalea T, Catena F, Kirkpatrick A, Khokha V, Parry N, Civil I, Leppaniemi A, Chirica M, Pikoulis E, Fraga GP, Chiarugi M, Damaskos D, Cicuttin E, Ceresoli M, De Simone B, Vega-Rivera F, Sartelli M, Biffl W, Ansaloni L, Weber DG, Coccolini F. AAST - WSES Guidelines on Diagnosis and Management of Peripheral Vascular Injuries. J Trauma Acute Care Surg. 2020 Oct 1. [Epub ahead of print] PubMed PMID: 33009335
  • Samuels JM, Sun K, Moore EE, Coleman JR, Fox CJ, Cohen MJ, Sauaia A, MacTaggart JN. Resuscitative endovascular balloon occlusion of the aorta-Interest is widespread but need for training persists. J Trauma Acute Care Surg. 2020 Oct;89(4):e112-e116. PubMed PMID: 33009200
  • Fox CJ, Moore EE. The posterior approach to the midpopliteal vessels is the preferred approach for an isolated knee injury. J Trauma Acute Care Surg. 2020 Oct;89(4):e101-e105. PubMed PMID: 33009199
  • Leasia K, Douglas I, Lawless R, Burlew CC, Platnick KB, Moore EE, Pieracci FM. Validation of current procedural terminology codes for surgical stabilization of rib fractures. Injury. 2020 Nov;51(11):2500-2506. PubMed PMID: 32962828
  • Heelan AA, Freedberg M, Moore EE, Platnick BK, Pieracci FM, Cohen MJ, Lawless R, Campion EM, Coleman JJ, Hoehn M, Burlew CC. Worth looking! venous thromboembolism in patients who undergo preperitoneal pelvic packing warrants screening duplex. Am J Surg. 2020 Dec;220(6):1395-1399. PubMed PMID: 32958159
  • DuBose JJ, Morrison J, Moore LJ, Cannon JW, Seamon MJ, Inaba K, Fox CJ, Moore EE, Feliciano DV, Scalea T. Does Clamshell Thoracotomy Better Facilitate Thoracic Life-Saving Procedures Without Increased Complication Compared with an Anterolateral Approach to Resuscitative Thoracotomy? Results from the American Association for the Surgery of Trauma Aortic Occlusion for Resuscitation in Trauma and Acute Care Surgery Registry. J Am Coll Surg. 2020 Dec;231(6):713-719.e1. PubMed PMID: 32947036
  • Barrett CD, Moore HB, Vigneshwar N, Dhara S, Chandler J, Chapman MP, Sauaia A, Moore EE, Yaffe MB. Plasmin TEG Rapidly Identifies Trauma Patients at Risk for Massive Transfusion, Mortality and Hyperfibrinolysis: A Diagnostic Tool to Resolve an International Debate on TXA?. J Trauma Acute Care Surg. 2020 Sep 9. [Epub ahead of print] PubMed PMID: 32925578
  • Gargur Assuncao A, Leasia K, White T, Majercik S, Gardner S, Mauffrey C, Parry J, Moore EE, Pieracci FM. Characterization and influence of ipsilateral scapula fractures among patients who undergo surgical stabilization of sub-scapular rib fractures. Eur J Orthop Surg Traumatol. 2020 Sep 9. [Epub ahead of print] PubMed PMID: 32909107
  • Stettler GR, Moore EE, Huebner BR, Nunns GR, Moore HB, Coleman JR, Kelher M, Banerjee A, Silliman CC. 28-day thawed plasma maintains a(2) -antiplasmin levels and inhibits tPA-induced fibrinolysis. Vox Sang. 2020 Sep 7. [Epub ahead of print] PubMed PMID: 32894784
  • Coleman JR, Leasia K, Douglas IS, Hosokawa P, Lawless RA, Moore EE, Pieracci F. Quantifying the expense of deferring surgical stabilization of rib fractures: Operative management of rib fractures is associated with significantly lower charges. J Trauma Acute Care Surg. 2020 Dec;89(6):1032-1038. PubMed PMID: 32890348
  • Dhara S, Moore EE, Yaffe MB, Moore HB, Barrett CD. Modern Management of Bleeding, Clotting, and Coagulopathy in Trauma Patients: What Is the Role of Viscoelastic Assays?. Curr Trauma Rep. 2020 Mar;6(1):69-81. PubMed PMID: 32864298
  • Moore HB, Barrett CD, Moore EE, Jhunjhnuwala R, McIntyre RC, Moore PK, Wang J, Hajizadeh N, Talmor DS, Sauaia A, Yaffe MB. STudy of Alteplase for Respiratory failure in SARS-Cov2/COVID-19: Study Design of the Phase IIa STARS Trial. Res Pract Thromb Haemost. 2020 May 21. [Epub ahead of print] PubMed PMID: 32838109
  • Perrone G, Sartelli M, Mario G, Chichom-Mefire A, Labricciosa FM, Abu-Zidan FM, Ansaloni L, Biffl WL, Ceresoli M, Coccolini F, Coimbra R, Demetrashvili Z, Di Saverio S, Fraga GP, Khokha V, Kirkpatrick AW, Kluger Y, Leppaniemi A, Maier RV, Moore EE, Negoi I, Ordonez CA, Sakakushev B, Lohse HAS, Velmahos GC, Wani I, Weber DG, Bonati E, Catena F. Management of intra-abdominal-infections: 2017 World Society of Emergency Surgery guidelines summary focused on remote areas and low-income nations. Int J Infect Dis. 2020 Oct;99:140-148. PubMed PMID: 32739433
  • Samuels JM, Sun K, Moore EE, Coleman JR, Fox CJ, Cohen MJ, Sauaia A, MacTaggart JN. REBOA - Interest is Widespread but Need for Training Persists. J Trauma Acute Care Surg. 2020 Jul 23. [Epub ahead of print] PubMed PMID: 32732667
  • Barrett CD, Vigneshwar N, Moore HB, Ghasabyan A, Chandler J, Moore EE, Yaffe MB. Tranexamic acid is associated with reduced complement activation in trauma patients with hemorrhagic shock and hyperfibrinolysis on thromboelastography. Blood Coagul Fibrinolysis. 2020 Dec;31(8):578-582. PubMed PMID: 32732500
  • Hatchimonji JS, Chipman AM, McGreevy DT, Hörer TM, Burruss S, Han S, Spalding MC, Fox CJ, Moore EE, Diaz JJ, Cannon JW. REBOA Use in Nontrauma Emergency General Surgery: A Multi-institutional Experience. J Surg Res. 2020 Jul 21;256:149-155. [Epub ahead of print] PubMed PMID: 32707397
  • DuBose JJ, Morrison JJ, Scalea TM, Rasmussen TE, Feliciano DV, Moore EE. Beyond the Crossroads: Who Will be the Caretakers of Vascular Injury Management?. Ann Surg. 2020 Aug;272(2):236-237. PubMed PMID: 32675533
  • Coleman JR, Burlew CC, Platnick KB, Campion E, Pieracci F, Lawless R, Werner N, Coleman J, Hoehn M, Moore EE, Cohen MJ. Maintaining Trauma Care Access During the COVID-19 Pandemic: An Urban, Level-1 Trauma Center's Experience. Ann Surg. 2020 Aug;272(2):e58-e60. PubMed PMID: 32675497
  • Ley EJ, Brown CVR, Moore EE, Sava JA, Peck K, Ciesla DJ, Sperry JL, Rizzo AG, Rosen NG, Brasel KJ, Kozar R, Inaba K, Martin MJ. Updated guidelines to reduce venous thromboembolism in trauma patients: A Western Trauma Association critical decisions algorithm. J Trauma Acute Care Surg. 2020 Nov;89(5):971-981. PubMed PMID: 32590563
  • Campion EM, Cralley A, Robinson C, Sauaia A, Pieracci FM, Lawless RA, Platnick B, Robinson J, Edwards D, McVaney K, Moore EE, Cohen MJ, Coleman JJ, Fox C, Burlew CC. Prehospital end-tidal carbon dioxide predicts massive transfusion and death following trauma. J Trauma Acute Care Surg. 2020 Oct;89(4):703-707. PubMed PMID: 32590557
  • Moore EE, Liu D, Pechman KR, Acosta LMY, Bell SP, Davis LT, Blennow K, Zetterberg H, Landman BA, Schrag MS, Hohman TJ, Gifford KA, Jefferson AL. Mild Cognitive Impairment Staging Yields Genetic Susceptibility, Biomarker, and Neuroimaging Differences. Front Aging Neurosci. 2020;12:139. PubMed PMID: 32581762
  • Coleman JR, Moore EE, Freeman K, Grubinger ND, Hennig GW, Cohen MJ, Samuels JM, Hansen K. Actin is associated with tissue injury in trauma patients and produces a hypercoagulable profile in vitro. J Trauma Acute Care Surg. 2020 Jul;89(1):87-95. PubMed PMID: 32574484
  • Barrett CD, Moore HB, Moore EE, McIntyre RC, Moore PK, Burke J, Hua F, Apgar J, Talmor DS, Sauaia A, Liptzin DR, Veress LA, Yaffe MB. Fibrinolytic therapy for refractory COVID-19 acute respiratory distress syndrome: Scientific rationale and review. Res Pract Thromb Haemost. 2020 May;4(4):524-531. PubMed PMID: 32542213
  • Ceresoli M, Coccolini F, Biffl WL, Sartelli M, Ansaloni L, Moore EE, Di Saverio S, Kluger Y, Catena F. WSES guidelines updates. World J Emerg Surg. 2020 Jun 10;15(1):39. PubMed PMID: 32522227
  • Archer DB, Moore EE, Shashikumar N, Dumitrescu L, Pechman KR, Landman BA, Gifford KA, Jefferson AL, Hohman TJ. Free-water metrics in medial temporal lobe white matter tract projections relate to longitudinal cognitive decline. Neurobiol Aging. 2020 Oct;94:15-23. PubMed PMID: 32502831
  • Leppäniemi A, Tolonen M, Tarasconi A, Segovia-Lohse H, Gamberini E, Kirkpatrick AW, Ball CG, Parry N, Sartelli M, Wolbrink D, van Goor H, Baiocchi G, Ansaloni L, Biffl W, Coccolini F, Di Saverio S, Kluger Y, Moore EE, Catena F. Executive summary: WSES Guidelines for the management of severe acute pancreatitis. J Trauma Acute Care Surg. 2020 Jun;88(6):888-890. PubMed PMID: 32459451
  • Parry J, Hwang J, Stahel CF, Henderson C, Nadeau J, Stacey S, Beauchamp K, Moore EE, Stahel PF. Soluble terminal complement activation fragment sC5b-9: a new serum biomarker for traumatic brain injury?. Eur J Trauma Emerg Surg. 2020 May 25. [Epub ahead of print] PubMed PMID: 32451568
  • Barrett CD, Oren-Grinberg A, Chao E, Moraco AH, Martin MJ, Reddy SH, Ilg AM, Jhunjhunwala R, Uribe M, Moore HB, Moore EE, Baedorf-Kassis EN, Krajewski ML, Talmor DS, Shaefi S, Yaffe MB. Rescue therapy for severe COVID-19-associated acute respiratory distress syndrome with tissue plasminogen activator: A case series. J Trauma Acute Care Surg. 2020 Sep;89(3):453-457. PubMed PMID: 32427773
  • Wright FL, Vogler TO, Moore EE, Moore HB, Wohlauer MV, Urban S, Nydam TL, Moore PK, McIntyre RC Jr. Fibrinolysis Shutdown Correlation with Thromboembolic Events in Severe COVID-19 Infection. J Am Coll Surg. 2020 Aug;231(2):193-203.e1. PubMed PMID: 32422349
  • Sartelli M, Weber DG, Kluger Y, Ansaloni L, Coccolini F, Abu-Zidan F, Augustin G, Ben-Ishay O, Biffl WL, Bouliaris K, Catena R, Ceresoli M, Chiara O, Chiarugi M, Coimbra R, Cortese F, Cui Y, Damaskos D, De' Angelis GL, Delibegovic S, Demetrashvili Z, De Simone B, Di Marzo F, Di Saverio S, Duane TM, Faro MP, Fraga GP, Gkiokas G, Gomes CA, Hardcastle TC, Hecker A, Karamarkovic A, Kashuk J, Khokha V, Kirkpatrick AW, Kok KYY, Inaba K, Isik A, Labricciosa FM, Latifi R, Leppäniemi A, Litvin A, Mazuski JE, Maier RV, Marwah S, McFarlane M, Moore EE, Moore FA, Negoi I, Pagani L, Rasa K, Rubio-Perez I, Sakakushev B, Sato N, Sganga G, Siquini W, Tarasconi A, Tolonen M, Ulrych J, Zachariah SK, Catena F. 2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting. World J Emerg Surg. 2020 May 7;15(1):32. PubMed PMID: 32381121
  • Moore EE, Gifford KA, Khan OA, Liu D, Pechman KR, Acosta LMY, Bell SP, Turchan M, Landman BA, Blennow K, Zetterberg H, Hohman TJ, Jefferson AL. Cerebrospinal fluid biomarkers of neurodegeneration, synaptic dysfunction, and axonal injury relate to atrophy in structural brain regions specific to Alzheimer's disease. Alzheimers Dement. 2020 Jun;16(6):883-895. PubMed PMID: 32378327
  • Coleman JR, Moore EE, Moore HB, Chapman MP, Cohen MJ, Silliman CC, Sauaia A. Tranexamic acid disturbs the dynamics of postinjury fibrinolysis. ANZ J Surg. 2020 Apr;90(4):420-422. PubMed PMID: 32339428
  • Moore HB, Tessmer MT, Moore EE, Sperry JL, Cohen MJ, Chapman MP, Pusateri AE, Guyette FX, Brown JB, Neal MD, Zuckerbraun B, Sauaia A. Forgot calcium? Admission ionized-calcium in two civilian randomized controlled trials of prehospital plasma for traumatic hemorrhagic shock. J Trauma Acute Care Surg. 2020 May;88(5):588-596. PubMed PMID: 32317575
  • Choudhury R, Barrett CD, Moore HB, Moore EE, McIntyre RC, Moore PK, Talmor DS, Nydam TL, Yaffe MB. Salvage use of tissue plasminogen activator (tPA) in the setting of acute respiratory distress syndrome (ARDS) due to COVID-19 in the USA: a Markov decision analysis. World J Emerg Surg. 2020 Apr 20;15(1):29. PubMed PMID: 32312290
  • Theodorou CM, Anderson JE, Brenner M, Scalea TM, Inaba K, Cannon J, Seamon M, Spalding MC, Fox CJ, Moore EE, DuBose JJ, Galante JM. Practice, Practice, Practice! Effect of Resuscitative Endovascular Balloon Occlusion of the Aorta Volume on Outcomes: Data From the AAST AORTA Registry. J Surg Res. 2020 Sep;253:18-25. PubMed PMID: 32311580
  • Barrett CD, Moore HB, Yaffe MB, Moore EE. ISTH interim guidance on recognition and management of coagulopathy in COVID-19: A comment. J Thromb Haemost. 2020 Aug;18(8):2060-2063. PubMed PMID: 32302462
  • Di Saverio S, Podda M, De Simone B, Ceresoli M, Augustin G, Gori A, Boermeester M, Sartelli M, Coccolini F, Tarasconi A, De' Angelis N, Weber DG, Tolonen M, Birindelli A, Biffl W, Moore EE, Kelly M, Soreide K, Kashuk J, Ten Broek R, Gomes CA, Sugrue M, Davies RJ, Damaskos D, Leppäniemi A, Kirkpatrick A, Peitzman AB, Fraga GP, Maier RV, Coimbra R, Chiarugi M, Sganga G, Pisanu A, De' Angelis GL, Tan E, Van Goor H, Pata F, Di Carlo I, Chiara O, Litvin A, Campanile FC, Sakakushev B, Tomadze G, Demetrashvili Z, Latifi R, Abu-Zidan F, Romeo O, Segovia-Lohse H, Baiocchi G, Costa D, Rizoli S, Balogh ZJ, Bendinelli C, Scalea T, Ivatury R, Velmahos G, Andersson R, Kluger Y, Ansaloni L, Catena F. Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines. World J Emerg Surg. 2020 Apr 15;15(1):27. PubMed PMID: 32295644
  • Moore HB, Barrett CD, Moore EE, McIntyre RC, Moore PK, Talmor DS, Moore FA, Yaffe MB. Is there a role for tissue plasminogen activator as a novel treatment for refractory COVID-19 associated acute respiratory distress syndrome?. J Trauma Acute Care Surg. 2020 Jun;88(6):713-714. PubMed PMID: 32281766
  • Coccolini F, Sartelli M, Kluger Y, Pikoulis E, Karamagioli E, Moore EE, Biffl WL, Peitzman A, Hecker A, Chirica M, Damaskos D, Ordonez C, Vega F, Fraga GP, Chiarugi M, Di Saverio S, Kirkpatrick AW, Abu-Zidan F, Mefire AC, Leppaniemi A, Khokha V, Sakakushev B, Catena R, Coimbra R, Ansaloni L, Corbella D, Catena F. COVID-19 the showdown for mass casualty preparedness and management: the Cassandra Syndrome. World J Emerg Surg. 2020 Apr 9;15(1):26. PubMed PMID: 32272957
  • Wang J, Hajizadeh N, Moore EE, McIntyre RC, Moore PK, Veress LA, Yaffe MB, Moore HB, Barrett CD. Tissue plasminogen activator (tPA) treatment for COVID-19 associated acute respiratory distress syndrome (ARDS): A case series. J Thromb Haemost. 2020 Jul;18(7):1752-1755. PubMed PMID: 32267998
  • Coccolini F, Coimbra R, Ordonez C, Kluger Y, Vega F, Moore EE, Biffl W, Peitzman A, Horer T, Abu-Zidan FM, Sartelli M, Fraga GP, Cicuttin E, Ansaloni L, Parra MW, Millán M, DeAngelis N, Inaba K, Velmahos G, Maier R, Khokha V, Sakakushev B, Augustin G, di Saverio S, Pikoulis E, Chirica M, Reva V, Leppaniemi A, Manchev V, Chiarugi M, Damaskos D, Weber D, Parry N, Demetrashvili Z, Civil I, Napolitano L, Corbella D, Catena F. Liver trauma: WSES 2020 guidelines. World J Emerg Surg. 2020 Mar 30;15(1):24. PubMed PMID: 32228707
  • Moore HB, Moore EE. Temporal Changes in Fibrinolysis following Injury. Semin Thromb Hemost. 2020 Mar;46(2):189-198. PubMed PMID: 32160644
  • Stettler GR, Moore EE, Nunns GR, Moore HB, Huebner BR, Silliman CC, Banerjee A, Sauaia A. Do not drink and lyse: alcohol intoxication increases fibrinolysis shutdown in injured patients. Eur J Trauma Emerg Surg. 2020 Mar 10. [Epub ahead of print] PubMed PMID: 32157340
  • Parry JA, Smith WR, Moore EE, Burlew CCC, Mauffrey C. The past, present, and future management of hemodynamic instability in patients with unstable pelvic ring injuries. Injury. 2020 Feb 22. [Epub ahead of print] PubMed PMID: 32115215
  • Moore HB, Gando S, Iba T, Kim PY, Yeh CH, Brohi K, Hunt BJ, Levy JH, Draxler DF, Stanworth S, Görlinger K, Neal MD, Schreiber MA, Barrett CD, Medcalf RL, Moore EE, Mutch NJ, Thachil J, Urano T, Thomas S, Scarlatescu E, Walsh M. Defining trauma-induced coagulopathy with respect to future implications for patient management: Communication from the SSC of the ISTH. J Thromb Haemost. 2020 Mar;18(3):740-747. PubMed PMID: 32112533
  • Chapman MP, Moore EE, Moore HB, Sauaia A. Plasma-first resuscitation to treat haemorrhagic shock in urban areas - Authors' reply. Lancet. 2020 Feb 22;395(10224):562-563. PubMed PMID: 32087789
  • Magee GA, Fox CJ, Moore EE. Resuscitative endovascular balloon occlusion of the aorta in pelvic ring fractures: The Denver Health protocol. Injury. 2020 Jan 31. [Epub ahead of print] PubMed PMID: 32057458
  • Catena F, Biffl W, De Simone B, Sartelli M, Di Saverio S, Kluger Y, Moore EE, Ansaloni L, Coccolini F. Emergency general surgeons: the special forces of general surgery (the "navy seals paradigm"). World J Emerg Surg. 2020 Feb 12;15(1):11. PubMed PMID: 32050987
  • Moore HB, Tessmer MT, Moore EE, Sperry JL, Cohen MJ, Chapman MP, Pusateri AE, Guyette FX, Brown JB, Neal M, Zuckerbraun B, Sauaia A. FORGOT CALCIUM? ADMISSION IONIZED-CALCIUM IN TWO CIVILIAN RANDOMIZED CONTROLLED TRIALS OF PRE-HOSPITAL PLASMA FOR TRAUMATIC HEMORRHAGIC SHOCK. J Trauma Acute Care Surg. 2020 Feb 10. [Epub ahead of print] PubMed PMID: 32044871
  • De Simone B, Sartelli M, Coccolini F, Ball CG, Brambillasca P, Chiarugi M, Campanile FC, Nita G, Corbella D, Leppaniemi A, Boschini E, Moore EE, Biffl W, Peitzmann A, Kluger Y, Sugrue M, Fraga G, Di Saverio S, Weber D, Sakakushev B, Chiara O, Abu-Zidan FM, Ten Broek R, Kirkpatrick AW, Wani I, Coimbra R, Baiocchi GL, Kelly MD, Ansaloni L, Catena F. Intraoperative surgical site infection control and prevention: a position paper and future addendum to WSES intra-abdominal infections guidelines. World J Emerg Surg. 2020 Feb 10;15(1):10. PubMed PMID: 32041636
  • Alam HB, Vercruysse G, Martin M, Brown CVR, Brasel K, Moore EE, Sava J, Ciesla D, Inaba K. Western Trauma Association critical decisions in trauma: Management of intracranial hypertension in patients with severe traumatic brain injuries. J Trauma Acute Care Surg. 2020 Feb;88(2):345-351. PubMed PMID: 31999657
  • Dow N, Coleman JR, Moore H, Osborn ZT, Sackheim AM, Hennig G, Butenas S, Nelson MT, Moore EE, Freeman K. Dense and dangerous: The tissue plasminogen activator-resistant fibrinolysis shutdown phenotype is due to abnormal fibrin polymerization. J Trauma Acute Care Surg. 2020 Feb;88(2):258-265. PubMed PMID: 31999655
  • Tarasconi A, Coccolini F, Biffl WL, Tomasoni M, Ansaloni L, Picetti E, Molfino S, Shelat V, Cimbanassi S, Weber DG, Abu-Zidan FM, Campanile FC, Di Saverio S, Baiocchi GL, Casella C, Kelly MD, Kirkpatrick AW, Leppaniemi A, Moore EE, Peitzman A, Fraga GP, Ceresoli M, Maier RV, Wani I, Pattonieri V, Perrone G, Velmahos G, Sugrue M, Sartelli M, Kluger Y, Catena F. Perforated and bleeding peptic ulcer: WSES guidelines. World J Emerg Surg. 2020;15:3. PubMed PMID: 31921329
  • Kovar A, Moskowitz E, Sauaia A, Moore EE, Platnick KB, Coleman JJ, Campion EM, Lawless RA, Cohen MJ, Pieracci FM, Burlew CC. Trends in hematologic markers after blunt splenic trauma: Risk factor or Epiphenomenon?. Am J Surg. 2020 Aug;220(2):489-494. PubMed PMID: 31879019
  • Pusateri AE, Moore EE, Moore HB, Le TD, Guyette FX, Chapman MP, Sauaia A, Ghasabyan A, Chandler J, McVaney K, Brown JB, Daley BJ, Miller RS, Harbrecht BG, Claridge JA, Phelan HA, Witham WR, Putnam AT, Sperry JL. Association of Prehospital Plasma Transfusion With Survival in Trauma Patients With Hemorrhagic Shock When Transport Times Are Longer Than 20 Minutes: A Post Hoc Analysis of the PAMPer and COMBAT Clinical Trials. JAMA Surg. 2020 Feb 1;155(2):e195085. PubMed PMID: 31851290
  • Coleman JR, Moore EE, Sauaia A, Samuels JM, Moore HB, Ghasabyan A, Chandler JG, Swope ML, Fleming CD, Banerjee A, Cohen MJ, Silliman CC, Peltz ED, Chapman MP. Untangling Sex Dimorphisms in Coagulation: Initial Steps Toward Precision Medicine for Trauma Resuscitation. Ann Surg. 2020 Jun;271(6):e128-e130. PubMed PMID: 31850983
  • Coleman JR, Moore EE, Silliman CC, Stettler GR, Nunns GR, Samuels JM, Bartley MG, Vigneshwar NG, Cohen MJ, Fragoso M, Sauaia A. Examining the Effect of Hypertonic Saline Administered for Reduction of Intracranial Hypertension on Coagulation. J Am Coll Surg. 2020 Mar;230(3):322-330.e2. PubMed PMID: 31843691
  • Moore HB, Cohen MJ, Moore EE. Comment on "The S100A10 Pathway Mediates an Occult Hyperfibrinolytic Subtype in Trauma Patients". Ann Surg. 2020 Apr;271(4):e110-e111. PubMed PMID: 31800497
  • Neal MD, Moore EE, Walsh M, Thomas S, Callcut RA, Kornblith LZ, Schreiber M, Ekeh AP, Singer AJ, Lottenberg L, Foreman M, Evans S, Winfield RD, Goodman MD, Freeman C, Milia D, Saillant N, Hartmann J, Achneck HE. A comparison between the TEG 6s and TEG 5000 analyzers to assess coagulation in trauma patients. J Trauma Acute Care Surg. 2020 Feb;88(2):279-285. PubMed PMID: 31738314
  • Ciesla DJ, Shatz DV, Moore EE, Sava J, Martin MJ, Brown CVR, Alam HB, Vercruysse GA, Brasel KJ, Inaba K. Western Trauma Association critical decisions in trauma: Cervical spine clearance in trauma patients. J Trauma Acute Care Surg. 2020 Feb;88(2):352-354. PubMed PMID: 31688829
  • Nelson JT, Coleman JR, Carmichael H, Mauffrey C, Vintimilla DR, Samuels JM, Sauaia A, Moore EE. High Rate of Fibrinolytic Shutdown and Venous Thromboembolism in Patients With Severe Pelvic Fracture. J Surg Res. 2020 Feb;246:182-189. PubMed PMID: 31593862
  • Moore HB, Moore BA, Sauaia A, Moore EE. Clinical relevance and practical assessment of fibrinolysis shutdown. ANZ J Surg. 2020 Apr;90(4):413-414. PubMed PMID: 31535453
  • Reitz KM, Moore HB, Guyette FX, Sauaia A, Pusateri AE, Moore EE, Hassoune A, Chapman MP, Daley BJ, Miller RS, Harbrecht BG, Claridge JA, Phelan HA, Brown JB, Zuckerbraun BS, Neal MD, Yazer MH, Sperry JL. Prehospital plasma in injured patients is associated with survival principally in blunt injury: Results from two randomized prehospital plasma trials. J Trauma Acute Care Surg. 2020 Jan;88(1):33-41. PubMed PMID: 31524836
  • Samuels JM, Coleman JR, Moore EE, Bartley M, Vigneshwar N, Cohen M, Silliman CC, Sauaia A, Banerjee A. Alternative Complement Pathway Activation Provokes a Hypercoagulable State with Diminished Fibrinolysis. Shock. 2020 May;53(5):560-565. PubMed PMID: 31441792
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Professional Memberships

  • American Association for Laboratory Animal Science, Member
  • American Association for the Surgery of Trauma, Board of Managers
  • American Board of Surgery, Guest Examiner
  • American College of Emergency Physicians, Committee on Trauma
  • American College of Nutrition, Member
  • American College of Surgeons (ACS), Board of Governors
  • American Medical Athletic Association, Member
  • American Physiology Society, Member
  • American Society for Parenteral and Enteral Nutrition, Member
  • American Surgical Association, Member
  • American Trauma Society, Member
  • Association for Academic Surgery, Member
  • Central Surgical Association, Member
  • Coalition for American Trauma Care, Member
  • Brazilian Society of Integrated Trauma Care , Honorary Member
  • Colombian Trauma Society, Honorary Member
  • Colorado Medical Society, Member
  • Denver Academy of Surgery , Member
  • Denver Medical Society, Member
  • Eastern Association for the Surgery of Trauma, Member
  • European Society for Trauma and Emergency Surgery , Member
  • Foundation for Critical Care, Member
  • International Association for Trauma Surgery and Intensive Care, Member
  • John H. Davis Society, Member
  • Panamerican Trauma Society, Board of Directors
  • Societe Internationale de Chirurgie, Member
  • Society of Critical Care Medicine, Member
  • Society for Leukocyte Biology, Member
  • Society of University Surgeons, Member
  • Southwestern Surgical Congress, Executive Council
  • Surgical Infection Society, Member
  • Trauma Association of Canada, Member
  • Western Surgical Association, Member
  • Western Trauma Association, Education for Foundation and Research

Practice Locations

Denver Health
777 Bannock St
Denver, CO 80204
303-436-6000

Hospital Affiliation
  • University of Colorado Hospital

Specialty Information

Conditions & Treatments
  • Surgery - Trauma and Acute Care
  • Urgent Care
  • Surgery - Laparoscopic Surgery
  • Surgery
  • Surgery - Major Liver Surgery (Hepatobiliary)
  • Surgery - Vascular Surgery

General Information

Medical Schools:
  • MD, University of Pittsburgh School of Medicine (1972)
Undergraduate Schools:
  • BS, Allegheny College (PA) (1968)
Internships:
  • University of Vermont Program (1973)
Residency Programs:
  • University of Vermont Program, Surgery (1976)
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Languages: English
Department: Surgery-GI, Trauma, and Endocrine Surgery
SOM Resources
CU Resources
Contact Us
(303) 724-0100
Building 500 N2229
somsupport@ucdenver.edu

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