Brent Palmer, PhD
Associate Professor, Medicine-Allergy/Clinical Immunology

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Graduate Schools :
  • MS, California State University Chico
  • PhD, Colorado State University
Undergraduate School:
  • BS, Colorado State University (CO)
Department: Medicine-Allergy/Clinical Immunology

Professional Titles

  • Associate Professor of Medicine
  • Technical Director, ClinImmune Flow Cytometry Laboratory
  • Director Allergy and Clinical Immunology Flow Cytometry Laboratory

Publications

  • Burkhart Colorado AS, Lazzaro A, Neff CP, Nusbacher N, Boyd K, Fiorillo S, Martin C, Siebert JC, Campbell TB, Borok M, Palmer BE, Lozupone C. Differential effects of antiretroviral treatment on immunity and gut microbiome composition in people living with HIV in rural versus urban Zimbabwe. Microbiome. 2024 Feb 3;12(1):18. PubMed PMID: 38310301
  • Carneiro VL, Littlefield KM, Watson R, Palmer BE, Lozupone C. Inflammation-associated gut microbiome in postacute sequelae of SARS-CoV-2 points towards new therapeutic targets. Gut. 2024 Jan 5;73(2):376-378. PubMed PMID: 36717218
  • Lazzaro A, Colorado ASB, Neff CP, Nusbacher N, Boyd K, Fiorillo S, Martin C, Siebert J, Campbell T, Borok M, Palmer B, Lozupone C. Antiretroviral treatment is less effective at reducing gut microbiome-associated inflammation and T cell activation in people living with HIV in rural versus urban Zimbabwe. Res Sq. 2023 Aug 31. PubMed PMID: 37693491
  • Schreiber AR, Santos J, McMahon B, Buckner TW, Olson C, Alberti MO, Guimarães-Young A, Knoeckel C, Broussard L, Aubrey M, Palmer BE, Weiss E, Connors GR, Brunner S, Wisell JA, Pacheco T, Aisner DL, Gutman JA. A Case of Fetal-Induced Graft-versus-Host Disease. N Engl J Med. 2023 Aug 17;389(7):668-670. PubMed PMID: 37585636
  • Arnolds KL, Yamada E, Neff CP, Schneider JM, Palmer BE, Lozupone CA. Disruption of Genes Encoding Putative Zwitterionic Capsular Polysaccharides of Diverse Intestinal Bacteroides Reduces the Induction of Host Anti-Inflammatory Factors. Microb Ecol. 2023 May;85(4):1620-1629. PubMed PMID: 35596750
  • Castleman MJ, Stumpf MM, Therrien NR, Smith MJ, Lesteberg KE, Palmer BE, Maloney JP, Janssen WJ, Mould KJ, Beckham JD, Pelanda R, Torres RM. SARS-CoV-2 infection relaxes peripheral B cell tolerance. J Exp Med. 2022 Jun 6;219(6). PubMed PMID: 35420627
  • Littlefield KM, Schneider JM, Neff CP, Soesanto V, Siebert JC, Nusbacher NM, Moreno-Huizar N, Cartwright IM, Armstrong AJS, Colgen SP, Lozupone CA, Palmer BE. Elevated inflammatory fecal immune factors in men who have sex with men with HIV associate with microbiome composition and gut barrier function. Front Immunol. 2022;13:1072720. PubMed PMID: 36605218
  • Castleman MJ, Stumpf MM, Therrien NR, Smith MJ, Lesteberg KE, Palmer BE, Maloney JP, Janssen WJ, Mould KJ, Beckham JD, Pelanda R, Torres RM. Autoantibodies elicited with SARS-CoV-2 infection are linked to alterations in double negative B cells. Front Immunol. 2022;13:988125. PubMed PMID: 36131937
  • Mahalingam R, Feia B, Coleman C, Anupindi K, Saravanan P, Luthens A, Bustillos A, Das A, de Haro E, Doyle-Meyers L, Looper J, Bubak AN, Niemeyer CS, Palmer B, Nagel MA, Traina-Dorge V. Simian Varicella Virus Pathogenesis in Skin during Varicella and Zoster. Viruses. 2022 May 27;14(6). PubMed PMID: 35746639
  • Littlefield KM, Watson RO, Schneider JM, Neff CP, Yamada E, Zhang M, Campbell TB, Falta MT, Jolley SE, Fontenot AP, Palmer BE. SARS-CoV-2-specific T cells associate with inflammation and reduced lung function in pulmonary post-acute sequalae of SARS-CoV-2. PLoS Pathog. 2022 May;18(5):e1010359. PubMed PMID: 35617421
  • Arnolds KL, Yamada E, Neff CP, Schneider JM, Palmer BE, Lozupone CA. Disruption of Genes Encoding Putative Zwitterionic Capsular Polysaccharides of Diverse Intestinal Bacteroides Reduces the Induction of Host Anti-Inflammatory Factors. Microb Ecol. 2022 May 21. [Epub ahead of print] PubMed PMID: 35596750
  • Castleman MJ, Stumpf MM, Therrien NR, Smith MJ, Lesteberg KE, Palmer BE, Maloney JP, Janssen WJ, Mould KJ, Beckham JD, Pelanda R, Torres RM. SARS-CoV-2 infection relaxes peripheral B cell tolerance. J Exp Med. 2022 Jun 6;219(6). PubMed PMID: 35420627
  • Leao V, Littlefield K., Palmer BE., Lozupone C. Inflammation-associated gut microbiome in post-acute sequelae of SARS-CoV-2 points towards new therapeutic targets. Gut Co-senior Author with Catherine Lozupone
  • Littlefield KM, Schneider JM, Neff CP, Soesanto V, Siebert JC, Nusbacher NM, Moreno-Huizar N, Cartwright IM, Armstrong AJS, Colgen SP, Lozupone CA, Palmer BE. Elevated inflammatory fecal immune factors in men who have sex with men with HIV associate with microbiome composition and gut barrier function. Front Immunol. 2022;13:1072720. PubMed PMID: 36605218
  • Castleman MJ, Stumpf MM, Therrien NR, Smith MJ, Lesteberg KE, Palmer BE, Maloney JP, Janssen WJ, Mould KJ, Beckham JD, Pelanda R, Torres RM. Autoantibodies elicited with SARS-CoV-2 infection are linked to alterations in double negative B cells. Front Immunol. 2022;13:988125. PubMed PMID: 36131937
  • Littlefield KM, Watson RO, Schneider JM, Neff CP, Yamada E, Zhang M, Campbell TB, Falta MT, Jolley SE, Fontenot AP, Palmer BE. SARS-CoV-2-specific T cells associate with inflammation and reduced lung function in pulmonary post-acute sequalae of SARS-CoV-2. PLoS Pathog. 2022 May;18(5):e1010359. PubMed PMID: 35617421
  • Arnolds KL, Yamada E, Neff CP, Schneider JM, Palmer BE, Lozupone CA. Disruption of Genes Encoding Putative Zwitterionic Capsular Polysaccharides of Diverse Intestinal Bacteroides Reduces the Induction of Host Anti-Inflammatory Factors. Microb Ecol. 2022 May 21. [Epub ahead of print] PubMed PMID: 35596750
  • Isak W. Tengesdal, Dinoop R Menon, Douglas G. Osborne, Charles P Neff, Nicholas E Powers, Fabia Gamboni, Adolfo G Mauro, Angelo D'Alessandro, Davide Stefoni, Morkos A Henen, Taylor S Mills, Dennis M DeGraaf, Tania Azam, Beat Vogeli, Brent E. Palmer, Eric M Pietras, James DeGregori, Aik Choon Tan Leo A. B. Joosten, Mayumi Fujita Charles A Dinarello, Carlo Marchetti. Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion" PNAS (In Press)
  • Yamada E, Martin CG, Moreno-Huizar N, Fouquier J, Neff CP, Coleman SL, Schneider JM, Huber J, Nusbacher NM, McCarter M, Campbell TB, Lozupone CA, Palmer BE. Intestinal microbial communities and Holdemanella isolated from HIV /- men who have sex with men increase frequencies of lamina propria CCR5( ) CD4( ) T cells. Gut Microbes. 2021 Jan-Dec;13(1):1997292. PubMed PMID: 34818131
  • Krsak M, Harry BL, Palmer BE, Franco-Paredes C. Response to Mishra et al . re "Postinfectious Immunity After COVID-19 and Vaccination Against SARS-CoV-2". Viral Immunol. 2021 Nov;34(9):659-660. PubMed PMID: 34672802
  • Arnold CG, Monte AA, Littlefield K, Vest A, Palmer BE. Vaccination Hesitancy and Postacute Sequelae of SARS-CoV-2: Is It Time to Reconsider?. Viral Immunol. 2021 Dec;34(10):666-668. PubMed PMID: 34491119
  • Krsak M, Harry BL, Palmer BE, Franco-Paredes C. Postinfectious Immunity After COVID-19 and Vaccination Against SARS-CoV-2. Viral Immunol. 2021 Oct;34(8):504-509. PubMed PMID: 34227891
  • Armstrong AJS, Quinn K, Fouquier J, Li SX, Schneider JM, Nusbacher NM, Doenges KA, Fiorillo S, Marden TJ, Higgins J, Reisdorph N, Campbell TB, Palmer BE, Lozupone CA. Systems Analysis of Gut Microbiome Influence on Metabolic Disease in HIV-Positive and High-Risk Populations. mSystems. 2021 May 18;6(3). PubMed PMID: 34006628
  • Tengesdal IW, Menon DR, Osborne DG, Neff CP, Powers NE, Gamboni F, Mauro AG, D'Alessandro A, Stefanoni D, Henen MA, Mills TS, De Graaf DM, Azam T, Vogeli B, Palmer BE, Pietras EM, DeGregori J, Tan AC, Joosten LAB, Fujita M, Dinarello CA, Marchetti C. Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10). PubMed PMID: 33649199
  • Coleman SL, Neff CP, Li SX, Armstrong AJS, Schneider JM, Sen S, Fennimore B, Campbell TB, Lozupone CA, Palmer BE. Can gut microbiota of men who have sex with men influence HIV transmission?. Gut Microbes. 2020 Feb 10;:1-10. [Epub ahead of print] PubMed PMID: 32036739
  • Neff CP, Atif SM, Logue EC, Siebert J, Görg C, Lavelle J, Fiorillo S, Twigg H, Campbell TB, Fontenot AP, Palmer BE. HIV Infection Is Associated with Loss of Anti-Inflammatory Alveolar Macrophages. J Immunol. 2020 Nov 1;205(9):2447-2455. PubMed PMID: 32929038
  • Walker ZJ, VanWyngarden MJ, Stevens BM, Abbott D, Hammes A, Langouët-Astrie C, Smith CA, Palmer BE, Forsberg PA, Mark TM, Jordan CT, Sherbenou DW. Measurement of ex vivo resistance to proteasome inhibitors, IMiDs, and daratumumab during multiple myeloma progression. Blood Adv. 2020 Apr 28;4(8):1628-1639. PubMed PMID: 32311014
  • Armstrong AJS, Shaffer M, Nusbacher NM, Griesmer C, Fiorillo S, Schneider JM, Neff CP, Li SX, Fontenot AP, Campbell T, Palmer BE, Lozupone CA. Correction to: An exploration of Prevotella-rich microbiomes in HIV and men who have sex with men. Microbiome. 2020 Apr 6;8(1):50. PubMed PMID: 32252810
  • Coleman SL, Neff CP, Li SX, Armstrong AJS, Schneider JM, Sen S, Fennimore B, Campbell TB, Lozupone CA, Palmer BE. Can gut microbiota of men who have sex with men influence HIV transmission?. Gut Microbes. 2020 May 3;11(3):610-619. PubMed PMID: 32036739
  • Okurut S, Meya DB, Bwanga F, Olobo J, Eller MA, Cham-Jallow F, Bohjanen PR, Pratap H, Palmer BE, Hullsiek KH, Manabe YC, Boulware DR, Janoff EN. B Cell Compartmentalization in Blood and Cerebrospinal Fluid of HIV-Infected Ugandans with Cryptococcal Meningitis. Infect Immun. 2020 Feb 20;88(3). PubMed PMID: 31871098
  • Jin Y, Roberts GHL, Ferrara TM, Ben S, van Geel N, Wolkerstorfer A, Ezzedine K, Siebert J, Neff CP, Palmer BE, Santorico SA, Spritz RA. Early-onset autoimmune vitiligo associated with an enhancer variant haplotype that upregulates class II HLA expression. Nat Commun. 2019 Jan 23;10(1):391. PubMed PMID: 30674883
  • Traina-Dorge V, Palmer BE, Coleman C, Hunter M, Frieman A, Gilmore A, Altrock K, Doyle-Meyers L, Nagel MA, Mahalingam R. Reactivation of Simian Varicella Virus in Rhesus Macaques after CD4 T Cell Depletion. J Virol. 2019 Feb 1;93(3). PubMed PMID: 30404798
  • Sam X Li, Sharon Sen, Jennifer M Schneider, Ka-Na Xiong, Nichole M Nusbacher, Nancy Moreno-Huizar, Michael Shaffer, Abigail JS Armstrong, Erin Severs4, Kristine Kuhn, Charles P Neff, Martin McCarter, Thomas Campbell, Catherine A Lozupone, and Brent E Palmer. Gut microbiota from high-risk men who have sex with men drive immune activation in gnotobiotic mice and in vitro HIV infection
  • Okurut S, Meya DB, Bwanga F, Olobo J, Eller MA, Cham-Jallow F, Bohjanen PR, Pratap H, Palmer BE, Hullsiek KH, Manabe YC, Boulware DR, Janoff EN. B cell Compartmentalization in Blood and Cerebrospinal Fluid of HIV- Infected Ugandans with Cryptococcal Meningitis. Infect Immun. 2019 Dec 23. [Epub ahead of print] PubMed PMID: 31871098
  • Janet Siebert, Carston Jorg, Brent E. Palmer and Catherine Lozupone. Visualizing microbiome–immune system interplay. Future Medicine, Immunotherapy Vol 11, #2 January 9, 2019
  • Siebert JC, Neff CP, Schneider JM, Regner EH, Ohri N, Kuhn KA, Palmer BE, Lozupone CA, Görg C. VOLARE: visual analysis of disease-associated microbiome-immune system interplay. BMC Bioinformatics. 2019 Aug 20;20(1):432. PubMed PMID: 31429723
  • Li SX, Sen S, Schneider JM, Xiong KN, Nusbacher NM, Moreno-Huizar N, Shaffer M, Armstrong AJS, Severs E, Kuhn K, Neff CP, McCarter M, Campbell T, Lozupone CA, Palmer BE. Gut microbiota from high-risk men who have sex with men drive immune activation in gnotobiotic mice and in vitro HIV infection. PLoS Pathog. 2019 Apr;15(4):e1007611. PubMed PMID: 30947289
  • Jones D, Como CN, Jing L, Blackmon A, Neff CP, Krueger O, Bubak AN, Palmer BE, Koelle DM, Nagel MA. Varicella zoster virus productively infects human peripheral blood mononuclear cells to modulate expression of immunoinhibitory proteins and blocking PD-L1 enhances virus-specific CD8 T cell effector function. PLoS Pathog. 2019 Mar;15(3):e1007650. PubMed PMID: 30870532
  • Li S, Amo-Aparicio J, Neff CP, Tengesdal IW, Azam T, Palmer BE, López-Vales R, Bufler P, Dinarello CA. Role for nuclear interleukin-37 in the suppression of innate immunity. Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4456-4461. PubMed PMID: 30792349
  • Jin Y, Roberts GHL, Ferrara TM, Ben S, van Geel N, Wolkerstorfer A, Ezzedine K, Siebert J, Neff CP, Palmer BE, Santorico SA, Spritz RA. Early-onset autoimmune vitiligo associated with an enhancer variant haplotype that upregulates class II HLA expression. Nat Commun. 2019 Jan 23;10(1):391. PubMed PMID: 30674883
  • Logue EC, Neff CP, Mack DG, Martin AK, Fiorillo S, Lavelle J, Vandivier RW, Campbell TB, Palmer BE, Fontenot AP. Upregulation of Chitinase 1 in Alveolar Macrophages of HIV-Infected Smokers. J Immunol. 2019 Mar 1;202(5):1363-1372. PubMed PMID: 30665939
  • Traina-Dorge V, Palmer BE, Coleman C, Hunter M, Frieman A, Gilmore A, Altrock K, Doyle-Meyers L, Nagel MA, Mahalingam R. Reactivation of Simian Varicella Virus in Rhesus Macaques after CD4 T Cell Depletion. J Virol. 2019 Feb 1;93(3). PubMed PMID: 30404798
  • Siebert JC, Görg C, Palmer B, Lozupone C. Visualizing microbiome-immune system interplay. Immunotherapy. 2019 Feb;11(2):63-67. PubMed PMID: 30730269
  • Nicholson LK, Pratap H, Bowers E, Gunzburger E, Bandi SR, Gardner EM, Palmer BE, Wright T, Kittelson J, Janoff EN. Effective B cell activation in vitro during viremic HIV-1 infection with surrogate T cell stimulation. Immunobiology. 2018 Dec;223(12):839-849. PubMed PMID: 30219203
  • Mahalingam R, Kaufer BB, Ouwendijk WJD, Verjans GMGM, Coleman C, Hunter M, Das A, Palmer BE, Clambey E, Nagel MA, Traina-Dorge V. Attenuation of Simian Varicella Virus Infection by Enhanced Green Fluorescent Protein in Rhesus Macaques. J Virol. 2018 Apr 1;92(7). PubMed PMID: 29343566
  • Neff CP, Krueger O, Xiong K, Arif S, Nusbacher N, Schneider JM, Cunningham AW, Armstrong A, Li S, McCarter MD, Campbell TB, Lozupone CA, Palmer BE. Fecal Microbiota Composition Drives Immune Activation in HIV-infected Individuals. EBioMedicine. 2018 Apr;30:192-202. PubMed PMID: 29650491
  • Bruno TC, Ebner PJ, Moore BL, Squalls OG, Waugh KA, Eruslanov EB, Singhal S, Mitchell JD, Franklin WA, Merrick DT, McCarter MD, Palmer BE, Kern JA, Slansky JE. Antigen-Presenting Intratumoral B Cells Affect CD4(+) TIL Phenotypes in Non-Small Cell Lung Cancer Patients. Cancer Immunol Res. 2017 Oct;5(10):898-907. PubMed PMID: 28848053
  • Presti RM, Flores SC, Palmer BE, Atkinson JJ, Lesko CR, Lau B, Fontenot AP, Roman J, McDyer JF, Twigg HL 3rd. Mechanisms Underlying HIV-Associated Noninfectious Lung Disease. Chest. 2017 Nov;152(5):1053-1060. PubMed PMID: 28427967
  • Cavalli G, Hayashi M, Jin Y, Yorgov D, Santorico SA, Holcomb C, Rastrou M, Erlich H, Tengesdal IW, Dagna L, Neff CP, Palmer BE, Spritz RA, Dinarello CA. MHC class II super-enhancer increases surface expression of HLA-DR and HLA-DQ and affects cytokine production in autoimmune vitiligo. Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1363-8. PubMed PMID: 26787888
  • Thompson M, Heath SL, Sweeton B, Williams K, Cunningham P, Keele BF, Sen S, Palmer BE, Chomont N, Xu Y, Basu R, Hellerstein MS, Kwa S, Robinson HL. DNA/MVA Vaccination of HIV-1 Infected Participants with Viral Suppression on Antiretroviral Therapy, followed by Treatment Interruption: Elicitation of Immune Responses without Control of Re-Emergent Virus. PLoS One. 2016 Oct 6;11(10):e0163164. PubMed PMID: 27711228
  • Neff CP, Rhodes ME, Arnolds KL, Collins CB, Donnelly J, Nusbacher N, Jedlicka P, Schneider JM, McCarter MD, Shaffer M, Mazmanian SK, Palmer BE, Lozupone CA. Diverse Intestinal Bacteria Contain Putative Zwitterionic Capsular Polysaccharides with Anti-inflammatory Properties. Cell Host Microbe. 2016 Oct 12;20(4):535-547. PubMed PMID: 27693306
  • Jones D, Blackmon A, Neff CP, Palmer BE, Gilden D, Badani H, Nagel MA. Varicella-Zoster Virus Downregulates Programmed Death Ligand 1 and Major Histocompatibility Complex Class I in Human Brain Vascular Adventitial Fibroblasts, Perineurial Cells, and Lung Fibroblasts. J Virol. 2016 Dec 1;90(23):10527-10534. PubMed PMID: 27630241
  • Seifert SM, Chen X, Meditz AL, Castillo-Mancilla JR, Gardner EM, Predhomme JA, Clayton C, Austin G, Palmer BE, Zheng JH, Klein B, Kerr BJ, Guida LA, Rower C, Rower JE, Kiser JJ, Bushman LR, MaWhinney S, Anderson PL. Intracellular Tenofovir and Emtricitabine Anabolites in Genital, Rectal, and Blood Compartments from First Dose to Steady State. AIDS Res Hum Retroviruses. 2016 Oct Nov;32(10-11):981-991. PubMed PMID: 27526873
  • Schade H, Sen S, Neff CP, Freed BM, Gao D, Gutman JA, Palmer BE. Programmed Death 1 Expression on CD4( ) T Cells Predicts Mortality after Allogeneic Stem Cell Transplantation. Biol Blood Marrow Transplant. 2016 Dec;22(12):2172-2179. PubMed PMID: 27519280
  • Palmer BE, Li SX, Lozupone CA. The HIV-Associated Enteric Microbiome Has Gone Viral. Cell Host Microbe. 2016 Mar 9;19(3):270-2. PubMed PMID: 26962936
  • Li SX, Armstrong A, Neff CP, Shaffer M, Lozupone CA, Palmer BE. Complexities of Gut Microbiome Dysbiosis in the Context of HIV Infection and Antiretroviral Therapy. Clin Pharmacol Ther. 2016 Jun;99(6):600-11. PubMed PMID: 26940481
  • Cavalli G, Hayashi M, Jin Y, Yorgov D, Santorico SA, Holcomb C, Rastrou M, Erlich H, Tengesdal IW, Dagna L, Neff CP, Palmer BE, Spritz RA, Dinarello CA. MHC class II super-enhancer increases surface expression of HLA-DR and HLA-DQ and affects cytokine production in autoimmune vitiligo. Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1363-8. PubMed PMID: 26787888
  • Li S, Neff CP, Barber K, Hong J, Luo Y, Azam T, Palmer BE, Fujita M, Garlanda C, Mantovani A, Kim S, Dinarello CA. Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8. Proc Natl Acad Sci U S A. 2015 Feb 5. [Epub ahead of print] PubMed PMID: 25654981
  • Akhmetzyanova I, Drabczyk M, Neff CP, Gibbert K, Dietze KK, Werner T, Liu J, Chen L, Lang KS, Palmer BE, Dittmer U, Zelinskyy G. Correction: PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8 T Cell Killing. PLoS Pathog. 2015 Dec;11(12):e1005364. PubMed PMID: 26684741
  • Akhmetzyanova I, Drabczyk M, Neff CP, Gibbert K, Dietze KK, Werner T, Liu J, Chen L, Lang KS, Palmer BE, Dittmer U, Zelinskyy G. PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8 T Cell Killing. PLoS Pathog. 2015 Oct;11(10):e1005224. PubMed PMID: 26484769
  • Beck JM, Schloss PD, Venkataraman A, Twigg H 3rd, Jablonski KA, Bushman FD, Campbell TB, Charlson ES, Collman RG, Crothers K, Curtis JL, Drews KL, Flores SC, Fontenot AP, Foulkes MA, Frank I, Ghedin E, Huang L, Lynch SV, Morris A, Palmer BE, Schmidt TM, Sodergren E, Weinstock GM, Young VB. Multicenter Comparison of Lung and Oral Microbiomes of HIV-infected and HIV-uninfected Individuals. Am J Respir Crit Care Med. 2015 Dec 1;192(11):1335-44. PubMed PMID: 26247840
  • Traina-Dorge V, Doyle-Meyers LA, Sanford R, Manfredo J, Blackmon A, Wellish M, James S, Alvarez X, Midkiff C, Palmer BE, Deharo E, Gilden D, Mahalingam R. Simian Varicella Virus Is Present in Macrophages, Dendritic Cells, and T Cells in Lymph Nodes of Rhesus Macaques after Experimental Reactivation. J Virol. 2015 Oct;89(19):9817-24. PubMed PMID: 26178993
  • Erlandson KM, Allshouse AA, Rapaport E, Palmer BE, Wilson CC, Weinberg A, MaWhinney S, Campbell TB. Physical function impairment of older, HIV-infected adults is associated with cytomegalovirus immunoglobulin response. AIDS Res Hum Retroviruses. 2015 Sep;31(9):905-12. PubMed PMID: 26061347
  • Castillo-Mancilla JR, Meditz A, Wilson C, Zheng JH, Palmer BE, Lee EJ, Gardner EM, Seifert S, Kerr B, Bushman LR, MaWhinney S, Anderson PL. Reduced immune activation during tenofovir-emtricitabine therapy in HIV-negative individuals. J Acquir Immune Defic Syndr. 2015 Apr 15;68(5):495-501. PubMed PMID: 25763783
  • Li S, Neff CP, Barber K, Hong J, Luo Y, Azam T, Palmer BE, Fujita M, Garlanda C, Mantovani A, Kim S, Dinarello CA. Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8. Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):2497-502. PubMed PMID: 25654981
  • Neff CP, Chain JL, MaWhinney S, Martin AK, Linderman DJ, Flores SC, Campbell TB, Palmer BE, Fontenot AP. Lymphocytic alveolitis is associated with the accumulation of functionally impaired HIV-specific T cells in the lung of antiretroviral therapy-naive subjects. Am J Respir Crit Care Med. 2015 Feb 15;191(4):464-73. PubMed PMID: 25536276
  • Meya DB, Okurut S, Zziwa G, Rolfes MA, Kelsey M, Cose S, Joloba M, Naluyima P, Palmer BE, Kambugu A, Mayanja-Kizza H, Bohjanen PR, Eller MA, Wahl SM, Boulware DR, Manabe YC, Janoff EN. Cellular immune activation in cerebrospinal fluid from ugandans with cryptococcal meningitis and immune reconstitution inflammatory syndrome. J Infect Dis. 2015 May 15;211(10):1597-606. PubMed PMID: 25492918
  • Meya DB, Okurut S, Zziwa G, Rolfes MA, Kelsey M, Cose S, Joloba M, Naluyima P, Palmer BE, Kambugu A, Mayanja-Kizza H, Bohjanen PR, Eller MA, Wahl SM, Boulware DR, Manabe YC, Janoff EN. Cellular Immune Activation in Cerebrospinal Fluid From Ugandans With Cryptococcal Meningitis and Immune Reconstitution Inflammatory Syndrome. J Infect Dis. 2014 Dec 9. [Epub ahead of print] PubMed PMID: 25492918
  • Lozupone CA, Rhodes ME, Neff CP, Fontenot AP, Campbell TB, Palmer BE. HIV-induced alteration in gut microbiota: driving factors, consequences, and effects of antiretroviral therapy. Gut Microbes. 2014 Jul 1;5(4):562-70. PubMed PMID: 25078714
  • López MC, Palmer BE, Lawrence DA. Naïve T cells, unconventional NK and NKT cells, and highly responsive monocyte-derived macrophages characterize human cord blood. Immunobiology. 2014 Oct;219(10):756-65. PubMed PMID: 24986635
  • James SF, Traina-Dorge V, Deharo E, Wellish M, Palmer BE, Gilden D, Mahalingam R. T cells increase before zoster and PD-1 expression increases at the time of zoster in immunosuppressed nonhuman primates latently infected with simian varicella virus. J Neurovirol. 2014 Jun;20(3):309-13. PubMed PMID: 24549971
  • Nold-Petry CA, Rudloff I, Baumer Y, Ruvo M, Marasco D, Botti P, Farkas L, Cho SX, Zepp JA, Azam T, Dinkel H, Palmer BE, Boisvert WA, Cool CD, Taraseviciene-Stewart L, Heinhuis B, Joosten LA, Dinarello CA, Voelkel NF, Nold MF. IL-32 promotes angiogenesis. J Immunol. 2014 Jan 15;192(2):589-602. PubMed PMID: 24337385
  • Morou A, Palmer BE, Kaufmann DE. Distinctive features of CD4+ T cell dysfunction in chronic viral infections. Curr Opin HIV AIDS. 2014 Sep;9(5):446-51. PubMed PMID: 25023623
  • Chain JL, Martin AK, Mack DG, Maier LA, Palmer BE, Fontenot AP. Impaired function of CTLA-4 in the lungs of patients with chronic beryllium disease contributes to persistent inflammation. J Immunol. 2013 Aug 15;191(4):1648-56. PubMed PMID: 23851684
  • Erlandson KM, Allshouse AA, Jankowski CM, Lee EJ, Rufner KM, Palmer BE, Wilson CC, MaWhinney S, Kohrt WM, Campbell TB. Association of functional impairment with inflammation and immune activation in HIV type 1-infected adults receiving effective antiretroviral therapy. J Infect Dis. 2013 Jul 15;208(2):249-59. PubMed PMID: 23559466
  • Golden-Mason L, McMahan RH, Strong M, Reisdorph R, Mahaffey S, Palmer BE, Cheng L, Kulesza C, Hirashima M, Niki T, Rosen HR. Galectin-9 functionally impairs natural killer cells in humans and mice. J Virol. 2013 May;87(9):4835-45. PubMed PMID: 23408620
  • Lozupone C, Cota-Gomez A, Palmer BE, Linderman DJ, Charlson ES, Sodergren E, Mitreva M, Abubucker S, Martin J, Yao G, Campbell TB, Flores SC, Ackerman G, Stombaugh J, Ursell L, Beck JM, Curtis JL, Young VB, Lynch SV, Huang L, Weinstock GM, Knox KS, Twigg H, Morris A, Ghedin E, Bushman FD, Collman RG, Knight R, Fontenot AP, Lung HIV Microbiome Project. Widespread colonization of the lung by Tropheryma whipplei in HIV infection. Am J Respir Crit Care Med. 2013 May 15;187(10):1110-7. PubMed PMID: 23392441
  • Lozupone CA, Li M, Campbell TB, Flores SC, Linderman D, Gebert MJ, Knight R, Fontenot AP, Palmer BE. Alterations in the gut microbiota associated with HIV-1 infection. Cell Host Microbe. 2013 Sep 11;14(3):329-39. PubMed PMID: 24034618
  • Palmer BE, Neff CP, Lecureux J, Ehler A, Dsouza M, Remling-Mulder L, Korman AJ, Fontenot AP, Akkina R. In vivo blockade of the PD-1 receptor suppresses HIV-1 viral loads and improves CD4+ T cell levels in humanized mice. J Immunol. 2013 Jan 1;190(1):211-9. PubMed PMID: 23209326
  • Kassu A, Marcus RA, D'Souza MB, Kelly-McKnight EA, Palmer BE. Suppression of HIV replication by antiretroviral therapy reduces TIM-3 expression on HIV-specific CD8(+) T cells. AIDS Res Hum Retroviruses. 2011 Jan;27(1):1-3. PubMed PMID: 20860535
  • Akkina R, Berges BK, Palmer BE, Remling L, Neff CP, Kuruvilla J, Connick E, Folkvord J, Gagliardi K, Kassu A, Akkina SR. Humanized Rag1-/- ?c-/- mice support multilineage hematopoiesis and are susceptible to HIV-1 infection via systemic and vaginal routes. PLoS One. 2011;6(6):e20169. PubMed PMID: 21695116
  • Kassu A, Marcus RA, D'Souza MB, Kelly-McKnight EA, Golden-Mason L, Akkina R, Fontenot AP, Wilson CC, Palmer BE. Regulation of virus-specific CD4+ T cell function by multiple costimulatory receptors during chronic HIV infection. J Immunol. 2010 Sep 1;185(5):3007-18. PubMed PMID: 20656923
  • Nold MF, Nold-Petry CA, Zepp JA, Palmer BE, Bufler P, Dinarello CA. IL-37 is a fundamental inhibitor of innate immunity. Nat Immunol. 2010 Nov;11(11):1014-22. PubMed PMID: 20935647
  • Matalon S, Palmer BE, Nold MF, Furlan A, Kassu A, Fossati G, Mascagni P, Dinarello CA. The histone deacetylase inhibitor ITF2357 decreases surface CXCR4 and CCR5 expression on CD4(+) T-cells and monocytes and is superior to valproic acid for latent HIV-1 expression in vitro. J Acquir Immune Defic Syndr. 2010 May 1;54(1):1-9. PubMed PMID: 20300007
  • Mack DG, Lanham AM, Falta MT, Palmer BE, Maier LA, Fontenot AP. Deficient and dysfunctional regulatory T cells in the lungs of chronic beryllium disease subjects. Am J Respir Crit Care Med. 2010 Jun 1;181(11):1241-9. PubMed PMID: 20299529
  • Golden-Mason L, Palmer BE, Kassam N, Townshend-Bulson L, Livingston S, McMahon BJ, Castelblanco N, Kuchroo V, Gretch DR, Rosen HR. Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells. J Virol. 2009 Sep;83(18):9122-30. PubMed PMID: 19587053
  • Mack DG, Lanham AM, Palmer BE, Maier LA, Fontenot AP. CD27 expression on CD4+ T cells differentiates effector from regulatory T cell subsets in the lung. J Immunol. 2009 Jun 1;182(11):7317-24. PubMed PMID: 19454729
  • Baumgartner JM, Gonzalez R, Lewis KD, Robinson WA, Richter DA, Palmer BE, Wilson CC, McCarter MD. Increased survival from stage IV melanoma associated with fewer regulatory T Cells. J Surg Res. 2009 Jun 1;154(1):13-20. PubMed PMID: 19062042
  • López MC, Palmer BE, Lawrence DA. Phenotypic differences between cord blood and adult peripheral blood. Cytometry B Clin Cytom. 2009 Jan;76(1):37-46. PubMed PMID: 18642326
  • Williams-Skipp C, Raman T, Valuck RJ, Watkins H, Palmer BE, Scheinman RI. Unmasking of a protective tumor necrosis factor receptor I-mediated signal in the collagen-induced arthritis model. Arthritis Rheum. 2009 Feb;60(2):408-18. PubMed PMID: 19180511
  • Kassu A, D'Souza M, O'Connor BP, Kelly-McKnight E, Akkina R, Fontenot AP, Palmer BE. Decreased 4-1BB expression on HIV-specific CD4+ T cells is associated with sustained viral replication and reduced IL-2 production. Clin Immunol. 2009 Aug;132(2):234-45. PubMed PMID: 19406689
  • Howe R, Dillon S, Rogers L, Palmer B, MaWhinney S, Blyveis N, Schlichtemeier R, D'Souza M, Ingoldby L, Harwood JE, Rietmeijer C, Ray G, Connick E, Wilson CC. Phenotypic and functional characterization of HIV-1-specific CD4+CD8+ double-positive T cells in early and chronic HIV-1 infection. J Acquir Immune Defic Syndr. 2009 Apr 15;50(5):444-56. PubMed PMID: 19360930
  • Mack DG, Lanham AK, Palmer BE, Maier LA, Watts TH, Fontenot AP. 4-1BB enhances proliferation of beryllium-specific T cells in the lung of subjects with chronic beryllium disease. J Immunol. 2008 Sep 15;181(6):4381-8. PubMed PMID: 18768897
  • Palmer BE, Mack DG, Martin AK, Gillespie M, Mroz MM, Maier LA, Fontenot AP. Up-regulation of programmed death-1 expression on beryllium-specific CD4+ T cells in chronic beryllium disease. J Immunol. 2008 Feb 15;180(4):2704-12. PubMed PMID: 18250483
  • Smyk-Pearson S, Tester IA, Klarquist J, Palmer BE, Pawlotsky JM, Golden-Mason L, Rosen HR. Spontaneous recovery in acute human hepatitis C virus infection: functional T-cell thresholds and relative importance of CD4 help. J Virol. 2008 Feb;82(4):1827-37. PubMed PMID: 18045940
  • Golden-Mason L, Palmer B, Klarquist J, Mengshol JA, Castelblanco N, Rosen HR. Upregulation of PD-1 expression on circulating and intrahepatic hepatitis C virus-specific CD8+ T cells associated with reversible immune dysfunction. J Virol. 2007 Sep;81(17):9249-58. PubMed PMID: 17567698
  • McCarter MD, Baumgartner J, Escobar GA, Richter D, Lewis K, Robinson W, Wilson C, Palmer BE, Gonzalez R. Immunosuppressive dendritic and regulatory T cells are upregulated in melanoma patients. Ann Surg Oncol. 2007 Oct;14(10):2854-60. PubMed PMID: 17593331
  • Anderson J, Li MJ, Palmer B, Remling L, Li S, Yam P, Yee JK, Rossi J, Zaia J, Akkina R. Safety and Efficacy of a Lentiviral Vector Containing Three Anti-HIV Genes-CCR5 Ribozyme, Tat-rev siRNA, and TAR Decoy-in SCID-hu Mouse-Derived T Cells. Mol Ther. 2007 Jun;15(6):1182-1188. PubMed PMID: 28182923
  • Anderson J, Li MJ, Palmer B, Remling L, Li S, Yam P, Yee JK, Rossi J, Zaia J, Akkina R. Safety and efficacy of a lentiviral vector containing three anti-HIV genes--CCR5 ribozyme, tat-rev siRNA, and TAR decoy--in SCID-hu mouse-derived T cells. Mol Ther. 2007 Jun;15(6):1182-8. PubMed PMID: 17406343
  • Baumgartner J, Wilson C, Palmer B, Richter D, Banerjee A, McCarter M. Melanoma induces immunosuppression by up-regulating FOXP3(+) regulatory T cells. J Surg Res. 2007 Jul;141(1):72-7. PubMed PMID: 17574040
  • Palmer BE, Mack DG, Martin AK, Maier LA, Fontenot AP. CD57 expression correlates with alveolitis severity in subjects with beryllium-induced disease. J Allergy Clin Immunol. 2007 Jul;120(1):184-91. PubMed PMID: 17416406
  • D'Souza M, Fontenot AP, Mack DG, Lozupone C, Dillon S, Meditz A, Wilson CC, Connick E, Palmer BE. Programmed death 1 expression on HIV-specific CD4+ T cells is driven by viral replication and associated with T cell dysfunction. J Immunol. 2007 Aug 1;179(3):1979-87. PubMed PMID: 17641065
  • Simonian PL, Roark CL, Diaz del Valle F, Palmer BE, Douglas IS, Ikuta K, Born WK, O'Brien RL, Fontenot AP. Regulatory role of gammadelta T cells in the recruitment of CD4+ and CD8+ T cells to lung and subsequent pulmonary fibrosis. J Immunol. 2006 Oct 1;177(7):4436-43. PubMed PMID: 16982878
  • Rohr JR, Sager T, Sesterhenn TM, Palmer BD. Exposure, postexposure, and density-mediated effects of atrazine on amphibians: breaking down net effects into their parts. Environ Health Perspect. 2006 Jan;114(1):46-50. PubMed PMID: 16393657
  • Fontenot AP, Palmer BE, Sullivan AK, Joslin FG, Wilson CC, Maier LA, Newman LS, Kotzin BL. Frequency of beryllium-specific, central memory CD4+ T cells in blood determines proliferative response. J Clin Invest. 2005 Oct;115(10):2886-93. PubMed PMID: 16151531
  • Pott GB, Palmer BE, Sullivan AK, Silviera L, Maier LA, Newman LS, Kotzin BL, Fontenot AP. Frequency of beryllium-specific, TH1-type cytokine-expressing CD4+ T cells in patients with beryllium-induced disease. J Allergy Clin Immunol. 2005 May;115(5):1036-42. PubMed PMID: 15867863
  • Palmer BE, Blyveis N, Fontenot AP, Wilson CC. Functional and phenotypic characterization of CD57+CD4+ T cells and their association with HIV-1-induced T cell dysfunction. J Immunol. 2005 Dec 15;175(12):8415-23. PubMed PMID: 16339584
  • Boritz E, Palmer BE, Wilson CC. Human immunodeficiency virus type 1 (HIV-1)-specific CD4+ T cells that proliferate in vitro detected in samples from most viremic subjects and inversely associated with plasma HIV-1 levels. J Virol. 2004 Nov;78(22):12638-46. PubMed PMID: 15507650
  • Palmer BE, Boritz E, Wilson CC. Effects of sustained HIV-1 plasma viremia on HIV-1 Gag-specific CD4+ T cell maturation and function. J Immunol. 2004 Mar 1;172(5):3337-47. PubMed PMID: 14978142
  • Anderson PD, Palmer B, Houpis JL, Smith MK, Pushnik JC. Chloroplastic responses of ponderosa pine (Pinus ponderosa) seedlings to ozone exposure. Environ Int. 2003 Jun;29(2-3):407-13. PubMed PMID: 12676234
  • Boritz E, Palmer BE, Livingston B, Sette A, Wilson CC. Diverse repertoire of HIV-1 p24-specific, IFN-gamma-producing CD4+ T cell clones following immune reconstitution on highly active antiretroviral therapy. J Immunol. 2003 Jan 15;170(2):1106-16. PubMed PMID: 12517980
  • Barron MA, Blyveis N, Palmer BE, MaWhinney S, Wilson CC. Influence of plasma viremia on defects in number and immunophenotype of blood dendritic cell subsets in human immunodeficiency virus 1-infected individuals. J Infect Dis. 2003 Jan 1;187(1):26-37. PubMed PMID: 12508143
  • Palmer BE, Boritz E, Blyveis N, Wilson CC. Discordance between frequency of human immunodeficiency virus type 1 (HIV-1)-specific gamma interferon-producing CD4(+) T cells and HIV-1-specific lymphoproliferation in HIV-1-infected subjects with active viral replication. J Virol. 2002 Jun;76(12):5925-36. PubMed PMID: 12021325
  • Rehage JS, Lynn SG, Hammond JI, Palmer BD, Sih A. Effects of larval exposure to triphenyltin on the survival, growth, and behavior of larval and juvenile Ambystoma barbouri salamanders. Environ Toxicol Chem. 2002 Apr;21(4):807-15. PubMed PMID: 11951955
  • Halsey WA Jr, Palmer BE, DeMartini JC, Howell MD. Analysis of sheep T-cell receptor beta-chain heterogeneity. Immunogenetics. 1999 Mar;49(3):206-14. PubMed PMID: 9914334
  • Beck JM, Newbury RL, Palmer BE, Warnock ML, Byrd PK, Kaltreider HB. Role of CD8+ lymphocytes in host defense against Pneumocystis carinii in mice. J Lab Clin Med. 1996 Nov;128(5):477-87. PubMed PMID: 8900290
  • Beck JM, Newbury RL, Palmer BE. Pneumocystis carinii pneumonia in scid mice induced by viable organisms propagated in vitro. Infect Immun. 1996 Nov;64(11):4643-7. PubMed PMID: 8890219
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Specialty Information

Specialties
  • Allergy and Immunology

General Information

Graduate Schools:
  • MS, California State University Chico (0001)
  • PhD, Colorado State University (0001)
Undergraduate Schools:
  • BS, Colorado State University (CO) (0001)
Department: Medicine-Allergy/Clinical Immunology
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