Vice Chair for Research, Department of Emergency Medicine
Director, CCTSI Trial Innovation Network
Director of Clinical Research, Department of Anesthesiology
Research Interests
My research focuses on epidemiological and clinical trials in the acute care setting, with a particularly focus on early care of critically ill and injured patients. Specifically, I have extensive experience with designing, overseeing, and implementing clinical trials in a variety of clinical environments including emergency department, inpatient (including intensive care unit), perioperative, and outpatient settings, particularly in the areas of acute respiratory failure and sepsis/infection (including COVID-19). I have been the lead investigator for 5 large multicenter clinical trials and participated in the design (as protocol committee member) and implementation (as site PI) of over a dozen other clinical trials. National leadership in clinical trials networks include the NHLBI Prevention and Early Treatment of Acute Lung Injury (PETAL) network executive and steering committees, the steering committee for the NHLBI Collaborating Network of Networks for Evaluating COVID-19 and Therapeutic Strategies (CONNECTS) and steering committee for the trans-NIH Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV)-3 platform trial. Funding for this work includes NIH (including NHLBI, NINDS, NIA, NCATS), DoD, CDC, foundation, and industry sponsors, and I have published over 150 original research articles in leading medical journals.
Teaching
Director, Emergency Medicine Scientist Training and Intensive Mentorship (EM-STIM) Program
(2012)
School of Medicine,
Emergency Medicine
Director of Clinical Research
(2017)
School of Medicine,
Anesthesiology
Vice Chair for Research
(2016)
School of Medicine,
Emergency Medicine
Publications
Fisher KA, Olson SM, Tenforde MW, Self WH, Wu M, Lindsell CJ, Shapiro NI, Files DC, Gibbs KW, Erickson HL, Prekker ME, Steingrub JS, Exline MC, Henning DJ, Wilson JG, Brown SM, Peltan ID, Rice TW, Hager DN, Ginde AA, Talbot HK, Casey JD, Grijalva CG, Flannery B, Patel MM, Feldstein LR. Symptoms and recovery among adult outpatients with and without COVID-19 at 11 healthcare facilities-July 2020, United States. Influenza Other Respir Viruses. 2021 Jan 6. [Epub ahead of print] PubMed PMID: 33405338
Clavijo CF, Oliva AM, Dingmann C, Kaizer A, Christians U, Burger E, Patel V, Kleck CJ, Vogel SA, Scott BK, Janik DJ, Jameson LC, Ginde AA. Toxicology Screening Testing in Patients Undergoing Spine Surgery: A Prospective Observational Pilot Study. Ther Drug Monit. 2021 Feb 1;43(1):136-138. PubMed PMID: 33181620
Lavonas EJ, Burnham RI, Schwarz J, Quackenbush E, Lewis B, Rose SR, Greene S, Toschlog EA, Charlton NP, Mullins ME, Schwartz R, Denning D, Sharma K, Kleinschmidt K, Bush SP, Anderson VE, Ginde AA, Gerardo CJ. Recovery from Copperhead Snake Envenomation: Role of Age, Sex, Bite Location, Severity, and Treatment. J Med Toxicol. 2020 Jan;16(1):17-23. PubMed PMID: 31482319
Casey JD, Johnson NJ, Semler MW, Collins SP, Aggarwal NR, Brower RG, Chang SY, Eppensteiner J, Filbin M, Gibbs KW, Ginde AA, Gong MN, Harrell F, Hayden DL, Hough CL, Khan A, Leither LM, Moss M, Oldmixon CF, Park PK, Reineck LA, Ringwood NJ, Robinson BRH, Schoenfeld DA, Shapiro NI, Steingrub JS, Torr DK, Weissman A, Lindsell CJ, Rice TW, Thompson BT, Brown SM, Self WH. Rationale and Design of ORCHID: A Randomized Placebo-controlled Clinical Trial of Hydroxychloroquine for Adults Hospitalized with COVID-19. Ann Am Thorac Soc. 2020 Sep;17(9):1144-1153. PubMed PMID: 32492354
Baehr A, Ledbetter C, Bookman KJ, Wang Y, Ginde AA, Wiler JL. Timeliness of Care for High-acuity Conditions at Hospital-affiliated Freestanding Emergency Departments. Acad Emerg Med. 2020 Oct;27(10):995-1001. PubMed PMID: 32352204
Ginde AA, Talmor D. High-Dose Vitamin D3 for Critically Ill Vitamin D-Deficient Patients. Reply. N Engl J Med. 2020 Apr 23;382(17):1670-1671. PubMed PMID: 32320585
Lundgren JD, Grund B, Barkauskas CE, Holland TL, Gottlieb RL, Sandkovsky U, Brown SM, Knowlton KU, Self WH, Files DC, Jain MK, Benfield T, Bowdish ME, Leshnower BG, Baker JV, Jensen JU, Gardner EM, Ginde AA, Harris ES, Johansen IS, Markowitz N, Matthay MA, Østergaard L, Chang CC, Davey VJ, Goodman A, Higgs ES, Murray DD, Murray TA, Paredes R, Parmar MKB, Phillips AN, Reilly C, Sharma S, Dewar RL, Teitelbaum M, Wentworth D, Cao H, Klekotka P, Babiker AG, Gelijns AC, Kan VL, Polizzotto MN, Thompson BT, Lane HC, Neaton JD. A Neutralizing Monoclonal Antibody for Hospitalized Patients with Covid-19. N Engl J Med. 2020 Dec 22. [Epub ahead of print] PubMed PMID: 33356051
Bedard AF, Mata LV, Dymond C, Moreira F, Dixon J, Schauer SG, Ginde AA, Bebarta V, Moore EE, Mould-Millman NK. A scoping review of worldwide studies evaluating the effects of prehospital time on trauma outcomes. Int J Emerg Med. 2020 Dec 9;13(1):64. PubMed PMID: 33297951
Jolliffe DA, Camargo CA, Sluyter JD, Aglipay M, Aloia JF, Ganmaa D, Bergman P, Borzutzky A, Damsgaard CT, Dubnov-Raz G, Esposito S, Gilham C, Ginde AA, Golan-Tripto I, Goodall EC, Grant CC, Griffiths CJ, Hibbs AM, Janssens W, Khadilkar AV, Laaksi I, Lee MT, Loeb M, Maguire JL, Majak P, Mauger DT, Manaseki-Holland S, Murdoch DR, Nakashima A, Neale RE, Pham H, Rake C, Rees JR, Rosendahl J, Scragg R, Shah D, Shimizu Y, Simpson-Yap S, Kumar GT, Urashima M, Martineau AR. Vitamin D supplementation to prevent acute respiratory infections: systematic review and meta-analysis of aggregate data from randomised controlled trials. medRxiv. 2020 Nov 25. PubMed PMID: 33269357
Self WH, Tenforde MW, Stubblefield WB, Feldstein LR, Steingrub JS, Shapiro NI, Ginde AA, Prekker ME, Brown SM, Peltan ID, Gong MN, Aboodi MS, Khan A, Exline MC, Files DC, Gibbs KW, Lindsell CJ, Rice TW, Jones ID, Halasa N, Talbot HK, Grijalva CG, Casey JD, Hager DN, Qadir N, Henning DJ, Coughlin MM, Schiffer J, Semenova V, Li H, Thornburg NJ, Patel MM. Decline in SARS-CoV-2 Antibodies After Mild Infection Among Frontline Health Care Personnel in a Multistate Hospital Network - 12 States, April-August 2020. MMWR Morb Mortal Wkly Rep. 2020 Nov 27;69(47):1762-1766. PubMed PMID: 33237893
Perman SM, Mikkelsen ME, Goyal M, Ginde A, Bhardwaj A, Drumheller B, Sante SC, Agarwal AK, Gaieski DF. The sensitivity of qSOFA calculated at triage and during emergency department treatment to rapidly identify sepsis patients. Sci Rep. 2020 Nov 23;10(1):20395. PubMed PMID: 33230117
Murray DD, Babiker AG, Baker JV, Barkauskas CE, Brown SM, Chang C, Davey VJ, Gelijns AC, Ginde AA, Grund B, Higgs E, Hudson F, Kan VL, Lane HC, Murray TA, Paredes R, Parmar MKB, Pett S, Phillips AN, Polizzotto MN, Reilly C, Sandkovsky U, Sharma S, Teitelbaum M, Thompson BT, Young BE, Neaton JD, Lundgren JD. Design and implementation of the multi-arm, multi-stage Therapeutics for Inpatients with COVID-19 (TICO) platform master protocol: An Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) initiative. medRxiv. 2020 Nov 12. PubMed PMID: 33215168
Self WH, Semler MW, Leither LM, Casey JD, Angus DC, Brower RG, Chang SY, Collins SP, Eppensteiner JC, Filbin MR, Files DC, Gibbs KW, Ginde AA, Gong MN, Harrell FE Jr, Hayden DL, Hough CL, Johnson NJ, Khan A, Lindsell CJ, Matthay MA, Moss M, Park PK, Rice TW, Robinson BRH, Schoenfeld DA, Shapiro NI, Steingrub JS, Ulysse CA, Weissman A, Yealy DM, Thompson BT, Brown SM, Steingrub J, Smithline H, Tiru B, Tidswell M, Kozikowski L, Thornton-Thompson S, De Souza L, Hou P, Baron R, Massaro A, Aisiku I, Fredenburgh L, Seethala R, Johnsky L, Riker R, Seder D, May T, Baumann M, Eldridge A, Lord C, Shapiro N, Talmor D, O’Mara T, Kirk C, Harrison K, Kurt L, Schermerhorn M, Banner-Goodspeed V, Boyle K, Dubosh N, Filbin M, Hibbert K, Parry B, Lavin-Parsons K, Pulido N, Lilley B, Lodenstein C, Margolin J, Brait K, Jones A, Galbraith J, Peacock R, Nandi U, Wachs T, Matthay M, Liu K, Kangelaris K, Wang R, Calfee C, Yee K, Hendey G, Chang S, Lim G, Qadir N, Tam A, Beutler R, Levitt J, Wilson J, Rogers A, Vojnik R, Roque J, Albertson T, Chenoweth J, Adams J, Pearson S, Juarez M, Almasri E, Fayed M, Hughes A, Hillard S, Huebinger R, Wang H, Vidales E, Patel B, Ginde A, Moss M, Baduashvili A, McKeehan J, Finck L, Higgins C, Howell M, Douglas I, Haukoos J, Hiller T, Lyle C, Cupelo A, Caruso E, Camacho C, Gravitz S, Finigan J, Griesmer C, Park P, Hyzy R, Nelson K, McDonough K, Olbrich N, Williams M, Kapoor R, Nash J, Willig M, Ford H, Gardner-Gray J, Ramesh M, Moses M, Ng Gong M, Aboodi M, Asghar A, Amosu O, Torres M, Kaur S, Chen JT, Hope A, Lopez B, Rosales K, Young You J, Mosier J, Hypes C, Natt B, Borg B, Salvagio Campbell E, Hite RD, Hudock K, Cresie A, Alhasan F, Gomez-Arroyo J, Duggal A, Mehkri O, Hastings A, Sahoo D, Abi Fadel F, Gole S, Shaner V, Wimer A, Meli Y, King A, Terndrup T, Exline M, Pannu S, Robart E, Karow S, Hough C, Robinson B, Johnson N, Henning D, Campo M, Gundel S, Seghal S, Katsandres S, Dean S, Khan A, Krol O, Jouzestani M, Huynh P, Weissman A, Yealy D, Scho... Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19: A Randomized Clinical Trial. JAMA. 2020 Dec 1;324(21):2165-2176. PubMed PMID: 33165621
Fisher KA, Olson SM, Tenforde MW, Feldstein LR, Lindsell CJ, Shapiro NI, Files DC, Gibbs KW, Erickson HL, Prekker ME, Steingrub JS, Exline MC, Henning DJ, Wilson JG, Brown SM, Peltan ID, Rice TW, Hager DN, Ginde AA, Talbot HK, Casey JD, Grijalva CG, Flannery B, Patel MM, Self WH. Telework Before Illness Onset Among Symptomatic Adults Aged =18 Years With and Without COVID-19 in 11 Outpatient Health Care Facilities - United States, July 2020. MMWR Morb Mortal Wkly Rep. 2020 Nov 6;69(44):1648-1653. PubMed PMID: 33151918
Feldstein LR, Self WH, Ferdinands JM, Randolph AG, Aboodi M, Baughman AH, Brown SM, Exline MC, Files DC, Gibbs K, Ginde AA, Gong MN, Grijalva CG, Halasa N, Khan A, Lindsell CJ, Newhams M, Peltan ID, Prekker ME, Rice TW, Shapiro NI, Steingrub J, Talbot HK, Halloran ME, Patel M. Incorporating real-time influenza detection into the test-negative design for estimating influenza vaccine effectiveness: The real-time test-negative design (rtTND). Clin Infect Dis. 2020 Sep 25. [Epub ahead of print] PubMed PMID: 32974644
Fisher KA, Tenforde MW, Feldstein LR, Lindsell CJ, Shapiro NI, Files DC, Gibbs KW, Erickson HL, Prekker ME, Steingrub JS, Exline MC, Henning DJ, Wilson JG, Brown SM, Peltan ID, Rice TW, Hager DN, Ginde AA, Talbot HK, Casey JD, Grijalva CG, Flannery B, Patel MM, Self WH. Community and Close Contact Exposures Associated with COVID-19 Among Symptomatic Adults =18 Years in 11 Outpatient Health Care Facilities - United States, July 2020. MMWR Morb Mortal Wkly Rep. 2020 Sep 11;69(36):1258-1264. PubMed PMID: 32915165
Self WH, Tenforde MW, Stubblefield WB, Feldstein LR, Steingrub JS, Shapiro NI, Ginde AA, Prekker ME, Brown SM, Peltan ID, Gong MN, Aboodi MS, Khan A, Exline MC, Files DC, Gibbs KW, Lindsell CJ, Rice TW, Jones ID, Halasa N, Talbot HK, Grijalva CG, Casey JD, Hager DN, Qadir N, Henning DJ, Coughlin MM, Schiffer J, Semenova V, Li H, Thornburg NJ, Patel MM. Seroprevalence of SARS-CoV-2 Among Frontline Health Care Personnel in a Multistate Hospital Network - 13 Academic Medical Centers, April-June 2020. MMWR Morb Mortal Wkly Rep. 2020 Sep 4;69(35):1221-1226. PubMed PMID: 32881855
Bennett CL, Sullivan AF, Ginde AA, Rogers J, Espinola JA, Clay CE, Camargo CA Jr. National Study of the Emergency Physician Workforce, 2020. Ann Emerg Med. 2020 Dec;76(6):695-708. PubMed PMID: 32747085
Tenforde MW, Kim SS, Lindsell CJ, Billig Rose E, Shapiro NI, Files DC, Gibbs KW, Erickson HL, Steingrub JS, Smithline HA, Gong MN, Aboodi MS, Exline MC, Henning DJ, Wilson JG, Khan A, Qadir N, Brown SM, Peltan ID, Rice TW, Hager DN, Ginde AA, Stubblefield WB, Patel MM, Self WH, Feldstein LR. Symptom Duration and Risk Factors for Delayed Return to Usual Health Among Outpatients with COVID-19 in a Multistate Health Care Systems Network - United States, March-June 2020. MMWR Morb Mortal Wkly Rep. 2020 Jul 31;69(30):993-998. PubMed PMID: 32730238
Casey JD, Johnson NJ, Semler MW, Collins SP, Aggarwal NR, Brower RG, Chang SY, Eppensteiner J, Filbin M, Gibbs KW, Ginde AA, Gong MN, Harrell F, Hayden DL, Hough CL, Khan A, Leither LM, Moss M, Oldmixon CF, Park PK, Reineck LA, Ringwood NJ, Robinson BRH, Schoenfeld DA, Shapiro NI, Steingrub JS, Torr DK, Weissman A, Lindsell CJ, Rice TW, Thompson BT, Brown SM, Self WH. Rationale and Design of ORCHID: A Randomized Placebo-controlled Clinical Trial of Hydroxychloroquine for Adults Hospitalized with COVID-19. Ann Am Thorac Soc. 2020 Sep;17(9):1144-1153. PubMed PMID: 32492354
Baehr A, Ledbetter C, Bookman KJ, Wang Y, Ginde AA, Wiler JL. Timeliness of Care for High-acuity Conditions at Hospital-affiliated Freestanding Emergency Departments. Acad Emerg Med. 2020 Oct;27(10):995-1001. PubMed PMID: 32352204
Ginde AA, Talmor D. High-Dose Vitamin D3 for Critically Ill Vitamin D-Deficient Patients. Reply. N Engl J Med. 2020 Apr 23;382(17):1670-1671. PubMed PMID: 32320585
Baehr A, Ledbetter C, Bookman KJ, Wang Y, Ginde AA, Wiler JL. Characteristics and Operational Performance of Hospital-affiliated Freestanding Emergency Departments. Med Care. 2020 Mar;58(3):234-240. PubMed PMID: 31876661
Lavonas EJ, Burnham RI, Schwarz J, Quackenbush E, Lewis B, Rose SR, Greene S, Toschlog EA, Charlton NP, Mullins ME, Schwartz R, Denning D, Sharma K, Kleinschmidt K, Bush SP, Anderson VE, Ginde AA, Gerardo CJ. Recovery from Copperhead Snake Envenomation: Role of Age, Sex, Bite Location, Severity, and Treatment. J Med Toxicol. 2020 Jan;16(1):17-23. PubMed PMID: 31482319
Martineau AR, Jolliffe DA, Greenberg L, Aloia JF, Bergman P, Dubnov-Raz G, Esposito S, Ganmaa D, Ginde AA, Goodall EC, Grant CC, Janssens W, Jensen ME, Kerley CP, Laaksi I, Manaseki-Holland S, Mauger D, Murdoch DR, Neale R, Rees JR, Simpson S, Stelmach I, Trilok Kumar G, Urashima M, Camargo CA, Griffiths CJ, Hooper RL. Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis. Health Technol Assess. 2019 Jan;23(2):1-44. PubMed PMID: 30675873
Larach MG, Klumpner TT, Brandom BW, Vaughn MT, Belani KG, Herlich A, Kim TW, Limoncelli J, Riazi S, Sivak EL, Capacchione J, Mashman D, Kheterpal S, Kooij F, Wilczak J, Soto R, Berris J, Price Z, Lins S, Coles P, Harris JM, Cummings KC 3rd, Berman MF, Nanamori M, Adelman BT, Wedeven C, LaGorio J, McCormick PJ, Tom S, Aziz MF, Coffman T, Ellis TA 2nd, Molina S, Peterson W, Mackey SC, van Klei WA, Ginde AA, Biggs DA, Neuman MD, Craft RM, Pace NL, Paganelli WC, Durieux ME, Nair BJ, Wanderer JP, Miller SA, Helsten DL, Turnbull ZA, Schonberger RB. Succinylcholine Use and Dantrolene Availability for Malignant Hyperthermia Treatment: Database Analyses and Systematic Review. Anesthesiology. 2019 Jan;130(1):41-54. PubMed PMID: 30550426
Baehr A, Ledbetter C, Bookman KJ, Wang Y, Ginde AA, Wiler JL. Characteristics and Operational Performance of Hospital-affiliated Freestanding Emergency Departments. Med Care. 2019 Dec 24. [Epub ahead of print] PubMed PMID: 31876661
Mould-Millman NK, Dixon J, Lamp A, de Vries S, Beaty B, Finck L, Colborn K, Moodley K, Skenadore A, Glasgow RE, Havranek EP, Bebarta VS, Ginde AA. A single-site pilot implementation of a novel trauma training program for prehospital providers in a resource-limited setting. Pilot Feasibility Stud. 2019;5:143. PubMed PMID: 31844551
Ginde AA, Brower RG, Caterino JM, Finck L, Banner-Goodspeed VM, Grissom CK, Hayden D, Hough CL, Hyzy RC, Khan A, Levitt JE, Park PK, Ringwood N, Rivers EP, Self WH, Shapiro NI, Thompson BT, Yealy DM, Talmor D. Early High-Dose Vitamin D(3) for Critically Ill, Vitamin D-Deficient Patients. N Engl J Med. 2019 Dec 26;381(26):2529-2540. PubMed PMID: 31826336
Evans CS, Self W, Ginde AA, Chandrasekhar R, Ely EW, Han JH. Vitamin D Deficiency and Long-Term Cognitive Impairment Among Older Adult Emergency Department Patients. West J Emerg Med. 2019 Oct 16;20(6):926-930. PubMed PMID: 31738720
Vogel JA, Rising KL, Jones J, Bowden ML, Ginde AA, Havranek EP. Reasons Patients Choose the Emergency Department over Primary Care: a Qualitative Metasynthesis. J Gen Intern Med. 2019 Nov;34(11):2610-2619. PubMed PMID: 31428988
Wilson J, Maloney K, Bookman K, Stoneback JW, Browne VA, Ginde A, Wallace M, Jacknin G, Cumbler E, Lewiss RE. Training Emergency Physicians in Ultrasound-guided Fascia Iliaca Compartment Blocks: Lessons in Change Management. Cureus. 2019 May 28;11(5):e4773. PubMed PMID: 31363454
Douin DJ, Schauer SG, Anderson EL, Jones J, DeSanto K, Cunningham CW, Bebarta VS, Ginde AA. Systematic review of oxygenation and clinical outcomes to inform oxygen targets in critically ill trauma patients. J Trauma Acute Care Surg. 2019 Oct;87(4):961-977. PubMed PMID: 31162333
Schauer SG, April MD, Naylor JF, Mould-Millman NK, Bebarta VS, Becker TE, Maddry JK, Ginde AA. Incidence of Hyperoxia in Combat Wounded in Iraq and Afghanistan: A Potential Opportunity for Oxygen Conservation. Mil Med. 2019 Dec 1;184(11-12):661-667. PubMed PMID: 31141134
Moss M, Huang DT, Brower RG, Ferguson ND, Ginde AA, Gong MN, Grissom CK, Gundel S, Hayden D, Hite RD, Hou PC, Hough CL, Iwashyna TJ, Khan A, Liu KD, Talmor D, Thompson BT, Ulysse CA, Yealy DM, Angus DC. Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome. N Engl J Med. 2019 May 23;380(21):1997-2008. PubMed PMID: 31112383
Zaidi AA, Dixon J, Lupez K, De Vries S, Wallis LA, Ginde A, Mould-Millman NK. The burden of trauma at a district hospital in the Western Cape Province of South Africa. Afr J Emerg Med. 2019;9(Suppl):S14-S20. PubMed PMID: 31073509
Perman SM, Siry BJ, Ginde AA, Grossestreuer AV, Abella BS, Daugherty SL, Havranek EP. Sex Differences in "Do Not Attempt Resuscitation" Orders After Out-of-Hospital Cardiac Arrest and the Relationship to Critical Hospital Interventions. Clin Ther. 2019 Jun;41(6):1029-1037. PubMed PMID: 31047712
Trent SA, Morse EA, Ginde AA, Havranek EP, Haukoos JS. Barriers to Prompt Presentation to Emergency Departments in Colorado after Onset of Stroke Symptoms. West J Emerg Med. 2019 Mar;20(2):237-243. PubMed PMID: 30881542
Martineau AR, Jolliffe DA, Greenberg L, Aloia JF, Bergman P, Dubnov-Raz G, Esposito S, Ganmaa D, Ginde AA, Goodall EC, Grant CC, Janssens W, Jensen ME, Kerley CP, Laaksi I, Manaseki-Holland S, Mauger D, Murdoch DR, Neale R, Rees JR, Simpson S, Stelmach I, Trilok Kumar G, Urashima M, Camargo CA, Griffiths CJ, Hooper RL. Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis. Health Technol Assess. 2019 Jan;23(2):1-44. PubMed PMID: 30675873
Larach MG, Klumpner TT, Brandom BW, Vaughn MT, Belani KG, Herlich A, Kim TW, Limoncelli J, Riazi S, Sivak EL, Capacchione J, Mashman D, Kheterpal S, Kooij F, Wilczak J, Soto R, Berris J, Price Z, Lins S, Coles P, Harris JM, Cummings KC 3rd, Berman MF, Nanamori M, Adelman BT, Wedeven C, LaGorio J, McCormick PJ, Tom S, Aziz MF, Coffman T, Ellis TA 2nd, Molina S, Peterson W, Mackey SC, van Klei WA, Ginde AA, Biggs DA, Neuman MD, Craft RM, Pace NL, Paganelli WC, Durieux ME, Nair BJ, Wanderer JP, Miller SA, Helsten DL, Turnbull ZA, Schonberger RB. Succinylcholine Use and Dantrolene Availability for Malignant Hyperthermia Treatment: Database Analyses and Systematic Review. Anesthesiology. 2019 Jan;130(1):41-54. PubMed PMID: 30550426
Trent SA, Jarou ZJ, Havranek EP, Ginde AA, Haukoos JS. Variation in Emergency Department Adherence to Treatment Guidelines for Inpatient Pneumonia and Sepsis: A Retrospective Cohort Study. Acad Emerg Med. 2019 Aug;26(8):908-920. PubMed PMID: 30343515
Saben JL, Shelton SK, Hopkinson AJ, Sonn BJ, Mills EB, Welham M, Westmoreland M, Zane R, Ginde AA, Bookman K, Oeth J, Chavez M, DeVivo M, Lakin A, Heldens J, Romero LB, Ames MJ, Roberts ER, Taylor M, Crooks K, Wicks SJ, Barnes KC, Monte AA. The Emergency Medicine Specimen Bank: An Innovative Approach To Biobanking In Acute Care. Acad Emerg Med. 2019 Jun;26(6):639-647. PubMed PMID: 30239069
Trent SA, Havranek EP, Ginde AA, Haukoos JS. Effect of Audit and Feedback on Physician Adherence to Clinical Practice Guidelines for Pneumonia and Sepsis. Am J Med Qual. 2019 May Jun;34(3):217-225. PubMed PMID: 30205697
Burke RE, Jones CD, Hosokawa P, Glorioso TJ, Coleman EA, Ginde AA. Influence of Nonindex Hospital Readmission on Length of Stay and Mortality. Med Care. 2018 Jan;56(1):85-90. PubMed PMID: 29087981
Clendenen N, Ginde A. Efficacy of platelet-rich plasma as conservative treatment in orthopaedics. Blood Transfus. 2018 Nov;16(6):473-474. PubMed PMID: 30388071
Trent SA, Jarou ZJ, Havranek EP, Ginde AA, Haukoos JS. Variation in Emergency Department Adherence to Treatment Guidelines for Inpatient Pneumonia and Sepsis: A Retrospective Cohort Study. Acad Emerg Med. 2018 Oct 21. [Epub ahead of print] PubMed PMID: 30343515
Saben JL, Shelton SK, Hopkinson AJ, Sonn BJ, Mills EB, Welham M, Westmoreland M, Zane R, Ginde AA, Bookman K, Oeth J, Chavez M, DeVivo M, Lakin A, Heldens J, Romero LB, Ames MJ, Roberts ER, Taylor M, Crooks K, Wicks SJ, Barnes KC, Monte AA. The Emergency Medicine Specimen Bank: An Innovative Approach To Biobanking In Acute Care. Acad Emerg Med. 2018 Sep 21. [Epub ahead of print] PubMed PMID: 30239069
Trent SA, Havranek EP, Ginde AA, Haukoos JS. Effect of Audit and Feedback on Physician Adherence to Clinical Practice Guidelines for Pneumonia and Sepsis. Am J Med Qual. 2018 Sep 12;:1062860618796947. [Epub ahead of print] PubMed PMID: 30205697
Self WH, Semler MW, Bellomo R, Brown SM, deBoisblanc BP, Exline MC, Ginde AA, Grissom CK, Janz DR, Jones AE, Liu KD, Macdonald SPJ, Miller CD, Park PK, Reineck LA, Rice TW, Steingrub JS, Talmor D, Yealy DM, Douglas IS, Shapiro NI. Liberal Versus Restrictive Intravenous Fluid Therapy for Early Septic Shock: Rationale for a Randomized Trial. Ann Emerg Med. 2018 Oct;72(4):457-466. PubMed PMID: 29753517
Leaf DE, Siew ED, Eisenga MF, Singh K, Mc Causland FR, Srivastava A, Ikizler TA, Ware LB, Ginde AA, Kellum JA, Palevsky PM, Wolf M, Waikar SS. Fibroblast Growth Factor 23 Associates with Death in Critically Ill Patients. Clin J Am Soc Nephrol. 2018 Apr 6;13(4):531-541. PubMed PMID: 29519954
Burke RE, Jones CD, Hosokawa P, Glorioso TJ, Coleman EA, Ginde AA. Influence of Nonindex Hospital Readmission on Length of Stay and Mortality. Med Care. 2018 Jan;56(1):85-90. PubMed PMID: 29087981
Martineau AR, Jolliffe DA, Hooper RL, Greenberg L, Aloia JF, Bergman P, Dubnov-Raz G, Esposito S, Ganmaa D, Ginde AA, Goodall EC, Grant CC, Griffiths CJ, Janssens W, Laaksi I, Manaseki-Holland S, Mauger D, Murdoch DR, Neale R, Rees JR, Simpson S Jr, Stelmach I, Kumar GT, Urashima M, Camargo CA Jr. Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. BMJ. 2017 Feb 15;356:i6583. PubMed PMID: 28202713
McNally JD, Ginde AA, Amrein K. Clarification needed for the systematic review of vitamin D trials in the ICU. Intensive Care Med. 2017 Jan 20. [Epub ahead of print] PubMed PMID: 28108767
Huang DT, Angus DC, Moss M, Thompson BT, Ferguson ND, Ginde A, Gong MN, Gundel S, Hayden DL, Hite RD, Hou PC, Hough CL, Iwashyna TJ, Liu KD, Talmor DS, Yealy DM. Design and Rationale of the Reevaluation of Systemic Early Neuromuscular Blockade Trial for Acute Respiratory Distress Syndrome. Ann Am Thorac Soc. 2017 Jan;14(1):124-133. PubMed PMID: 27779896
Colbert JF, Schmidt EP, Faubel S, Ginde AA. Severe Sepsis Outcomes Among Hospitalizations With Inflammatory Bowel Disease. Shock. 2017 Feb;47(2):128-131. PubMed PMID: 27617672
Burke RE, Jones CD, Coleman EA, Falvey JR, Stevens-Lapsley JE, Ginde AA. Use of post-acute care after hospital discharge in urban and rural hospitals. Am J Accountable Care. 2017 Mar;5(1):16-22. PubMed PMID: 29152607
Neudecker V, Brodsky KS, Clambey ET, Schmidt EP, Packard TA, Davenport B, Standiford TJ, Weng T, Fletcher AA, Barthel L, Masterson JC, Furuta GT, Cai C, Blackburn MR, Ginde AA, Graner MW, Janssen WJ, Zemans RL, Evans CM, Burnham EL, Homann D, Moss M, Kreth S, Zacharowski K, Henson PM, Eltzschig HK. Neutrophil transfer of miR-223 to lung epithelial cells dampens acute lung injury in mice. Sci Transl Med. 2017 Sep 20;9(408). PubMed PMID: 28931657
Colbert JF, Ford JA, Haeger SM, Yang Y, Dailey KL, Allison KC, Neudecker V, Evans CM, Richardson VL, Brodsky KS, Faubel S, Eltzschig HK, Schmidt EP, Ginde AA. A model-specific role of microRNA-223 as a mediator of kidney injury during experimental sepsis. Am J Physiol Renal Physiol. 2017 Aug 1;313(2):F553-F559. PubMed PMID: 28515178
Bookman K, West D, Ginde A, Wiler J, McIntyre R, Hammes A, Carlson N, Steinbruner D, Solley M, Zane R. Embedded Clinical Decision Support in Electronic Health Record Decreases Use of High-cost Imaging in the Emergency Department: EmbED study. Acad Emerg Med. 2017 Jul;24(7):839-845. PubMed PMID: 28391603
Ginde AA, Blatchford P. Reply to: Analysis Leads to Unreliable Results in Study of Vitamin D and Acute Respiratory Infection. J Am Geriatr Soc. 2017 May;65(5):1103-1104. PubMed PMID: 28369723
Chidi OO, Perman SM, Ginde AA. Characteristics of Short-stay Critical Care Admissions From Emergency Departments in Maryland. Acad Emerg Med. 2017 Oct;24(10):1204-1211. PubMed PMID: 28323374
Mould-Millman NK, Dixon JM, Sefa N, Yancey A, Hollong BG, Hagahmed M, Ginde AA, Wallis LA. The State of Emergency Medical Services (EMS) Systems in Africa. Prehosp Disaster Med. 2017 Jun;32(3):273-283. PubMed PMID: 28228178
Martineau AR, Jolliffe DA, Hooper RL, Greenberg L, Aloia JF, Bergman P, Dubnov-Raz G, Esposito S, Ganmaa D, Ginde AA, Goodall EC, Grant CC, Griffiths CJ, Janssens W, Laaksi I, Manaseki-Holland S, Mauger D, Murdoch DR, Neale R, Rees JR, Simpson S Jr, Stelmach I, Kumar GT, Urashima M, Camargo CA Jr. Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. BMJ. 2017 Feb 15;356:i6583. PubMed PMID: 28202713
McNally JD, Ginde AA, Amrein K. Clarification needed for the systematic review of vitamin D trials in the ICU. Intensive Care Med. 2017 Apr;43(4):595-596. PubMed PMID: 28108767
Ginde AA, Blatchford P, Breese K, Zarrabi L, Linnebur SA, Wallace JI, Schwartz RS. High-Dose Monthly Vitamin D for Prevention of Acute Respiratory Infection in Older Long-Term Care Residents: A Randomized Clinical Trial. J Am Geriatr Soc. 2017 Mar;65(3):496-503. PubMed PMID: 27861708
Huang DT, Angus DC, Moss M, Thompson BT, Ferguson ND, Ginde A, Gong MN, Gundel S, Hayden DL, Hite RD, Hou PC, Hough CL, Iwashyna TJ, Liu KD, Talmor DS, Yealy DM. Design and Rationale of the Reevaluation of Systemic Early Neuromuscular Blockade Trial for Acute Respiratory Distress Syndrome. Ann Am Thorac Soc. 2017 Jan;14(1):124-133. PubMed PMID: 27779896
Colbert JF, Schmidt EP, Faubel S, Ginde AA. Severe Sepsis Outcomes Among Hospitalizations With Inflammatory Bowel Disease. Shock. 2017 Feb;47(2):128-131. PubMed PMID: 27617672
Jones CD, Wald HL, Boxer RS, Masoudi FA, Burke RE, Capp R, Coleman EA, Ginde AA. Characteristics Associated with Home Health Care Referrals at Hospital Discharge: Results from the 2012 National Inpatient Sample. Health Serv Res. 2017 Apr;52(2):879-894. PubMed PMID: 27196526
Neudecker V, Brodsky KS, Kreth S, Ginde AA, Eltzschig HK. Emerging Roles for MicroRNAs in Perioperative Medicine. Anesthesiology. 2016 Feb;124(2):489-506. PubMed PMID: 26632665
Ginde AA, Blatchford P, Breese K, Zarrabi L, Linnebur SA, Wallace JI, Schwartz RS. High-Dose Monthly Vitamin D for Prevention of Acute Respiratory Infection in Older Long-Term Care Residents: A Randomized Clinical Trial. J Am Geriatr Soc. 2016 Nov 16. [Epub ahead of print] PubMed PMID: 27861708
Sarkari NN, Perman SM, Ginde AA. Impact of early do-not-attempt-resuscitation orders on procedures and outcomes of severe sepsis. J Crit Care. 2016 Dec;36:134-139. PubMed PMID: 27546762
Colbert JF, Traystman RJ, Poisson SN, Herson PS, Ginde AA. Sex-Related Differences in the Risk of Hospital-Acquired Sepsis and Pneumonia Post Acute Ischemic Stroke. J Stroke Cerebrovasc Dis. 2016 Oct;25(10):2399-404. PubMed PMID: 27363622
Libby AM, Hosokawa PW, Fairclough DL, Prochazka AV, Jones PJ, Ginde AA. Grant Success for Early-Career Faculty in Patient-Oriented Research: Difference-in-Differences Evaluation of an Interdisciplinary Mentored Research Training Program. Acad Med. 2016 Jun 21. [Epub ahead of print] PubMed PMID: 27332867
Holst JA, Perman SM, Capp R, Haukoos JS, Ginde AA. Undertriage of Trauma-Related Deaths in U.S. Emergency Departments. West J Emerg Med. 2016 May;17(3):315-23. PubMed PMID: 27330664
Jones CD, Wald HL, Boxer RS, Masoudi FA, Burke RE, Capp R, Coleman EA, Ginde AA. Characteristics Associated with Home Health Care Referrals at Hospital Discharge: Results from the 2012 National Inpatient Sample. Health Serv Res. 2016 May 16. [Epub ahead of print] PubMed PMID: 27196526
Neudecker V, Brodsky KS, Kreth S, Ginde AA, Eltzschig HK. Emerging Roles for MicroRNAs in Perioperative Medicine. Anesthesiology. 2016 Feb;124(2):489-506. PubMed PMID: 26632665
Burke RE, Whitfield EA, Hittle D, Min SJ, Levy C, Prochazka AV, Coleman EA, Schwartz R, Ginde AA. Hospital Readmission From Post-Acute Care Facilities: Risk Factors, Timing, and Outcomes. J Am Med Dir Assoc. 2016 Mar 1;17(3):249-55. PubMed PMID: 26715357
Jekich BM, Drake BD, Nacht JY, Nichols A, Ginde AA, Davis CB. Avalanche Fatalities in the United States: A Change in Demographics. Wilderness Environ Med. 2016 Mar;27(1):46-52. PubMed PMID: 26948553
Abbate LM, Perman SM, Ginde AA, Clambey ET, Van Pelt RE. Age Modifies the Association Between Obesity and Mortality in Individuals Hospitalized with Severe Sepsis. J Am Geriatr Soc. 2016 Apr;64(4):882-3. PubMed PMID: 27100585
Wiler JL, Ozkaynak M, Bookman K, Koehler A, Leeret R, Chua-Tuan J, Ginde AA, Zane R. Implementation of a Front-End Split-Flow Model to Promote Performance in an Urban Academic Emergency Department. Jt Comm J Qual Patient Saf. 2016 Jun;42(6):271-80. PubMed PMID: 27184243
Burke RE, Rooks SP, Levy C, Schwartz R, Ginde AA. Identifying Potentially Preventable Emergency Department Visits by Nursing Home Residents in the United States. J Am Med Dir Assoc. 2015 Feb 18. [Epub ahead of print] PubMed PMID: 25703449
Capp R, Horton CL, Takhar SS, Ginde AA, Peak DA, Zane R, Marill KA. Predictors of Patients Who Present to the Emergency Department With Sepsis and Progress to Septic Shock Between 4 and 48 Hours of Emergency Department Arrival. Crit Care Med. 2015 Jan 30. [Epub ahead of print] PubMed PMID: 25668750
Wiler JL, Ginde AA. State laws governing physician assistant practice in the United States and the impact on emergency medicine. J Emerg Med. 2015 Feb;48(2):e49-58. PubMed PMID: 25453855
Burke RE, Juarez-Colunga E, Levy C, Prochazka AV, Coleman EA, Ginde AA. Rise of Post-Acute Care Facilities as a Discharge Destination of US Hospitalizations. JAMA Intern Med. 2015 Feb 1;175(2):295-6. PubMed PMID: 25437642
Mould-Millman NK, Rominski SD, Bogus J, Ginde AA, Zakariah AN, Boatemaah CA, Yancey AH, Akoriyea SK, Campbell TB. Barriers to Accessing Emergency Medical Services in Accra, Ghana: Development of a Survey Instrument and Initial Application in Ghana. Glob Health Sci Pract. 2015 Dec;3(4):577-90. PubMed PMID: 26681705
Kork F, Balzer F, Spies CD, Wernecke KD, Ginde AA, Jankowski J, Eltzschig HK. Minor Postoperative Increases of Creatinine Are Associated with Higher Mortality and Longer Hospital Length of Stay in Surgical Patients. Anesthesiology. 2015 Dec;123(6):1301-11. PubMed PMID: 26492475
Lum HD, Ginde AA, Betz ME. Older adult drivers living in residential care facilities. Ann Longterm Care. 2015 Jul;23(7):21-26. PubMed PMID: 26366125
Jones CD, Ginde AA, Burke RE, Wald HL, Masoudi FA, Boxer RS. Increasing Home Healthcare Referrals upon Discharge from U.S. Hospitals: 2001-2012. J Am Geriatr Soc. 2015 Jun;63(6):1265-6. PubMed PMID: 26096410
Capp R, Horton CL, Takhar SS, Ginde AA, Peak DA, Zane R, Marill KA. Predictors of patients who present to the emergency department with sepsis and progress to septic shock between 4 and 48 hours of emergency department arrival. Crit Care Med. 2015 May;43(5):983-8. PubMed PMID: 25668750
Vinton DT, Capp R, Rooks SP, Abbott JT, Ginde AA. Frequent users of US emergency departments: characteristics and opportunities for intervention. Emerg Med J. 2014 Jan 28. [Epub ahead of print] PubMed PMID: 24473411
Ginde AA, Moss M. Lung-protective Ventilation in Emergency Department Patients With Severe Sepsis. Acad Emerg Med. 2014 Jan;21(1):96-7. PubMed PMID: 24320970
Leaf DE, Raed A, Donnino MW, Ginde AA, Waikar SS. Reply: active and native vitamin D in critical illness. Am J Respir Crit Care Med. 2014 Nov 15;190(10):1194-6. PubMed PMID: 25398113
Pukurdpol P, Wiler JL, Hsia RY, Ginde AA. Association of Medicare and Medicaid insurance with increasing primary care-treatable emergency department visits in the United States. Acad Emerg Med. 2014 Oct;21(10):1135-42. PubMed PMID: 25308137
Pukurdpol P, Wiler JL, Hsia RY, Ginde AA. Association of Medicare and Medicaid insurance with increasing primary care-treatable emergency department visits in the United States. Acad Emerg Med. 2014 Oct;21(10):1135-42. PubMed PMID: 25308137
Burke RE, Jones CD, Levy C, Ginde AA. Electronic communication capabilities of residential care facilities at times of transition. J Am Geriatr Soc. 2014 Jul;62(7):1381-3. PubMed PMID: 25039508
Leaf DE, Raed A, Donnino MW, Ginde AA, Waikar SS. Randomized controlled trial of calcitriol in severe sepsis. Am J Respir Crit Care Med. 2014 Sep 1;190(5):533-41. PubMed PMID: 25029202
Ginde AA, Blatchford PJ, Trzeciak S, Hollander JE, Birkhahn R, Otero R, Osborn TM, Moretti E, Nguyen HB, Gunnerson KJ, Milzman D, Gaieski DF, Goyal M, Cairns CB, Rivers EP, Shapiro NI. Age-related differences in biomarkers of acute inflammation during hospitalization for sepsis. Shock. 2014 Aug;42(2):99-107. PubMed PMID: 24978893
Jovanovich AJ, Ginde AA, Holmen J, Jablonski K, Allyn RL, Kendrick J, Chonchol M. Vitamin D level and risk of community-acquired pneumonia and sepsis. Nutrients. 2014 Jun 10;6(6):2196-205. PubMed PMID: 24918697
Betz ME, Ginde AA, Southerland LT, Caterino JM. Emergency department and outpatient treatment of acute injuries in older adults in the United States: 2009-2010. J Am Geriatr Soc. 2014 Jul;62(7):1317-23. PubMed PMID: 24890363
Lum HD, Mody L, Levy CR, Ginde AA. Pandemic influenza plans in residential care facilities. J Am Geriatr Soc. 2014 Jul;62(7):1310-6. PubMed PMID: 24852422
Sawyer BT, Ginde AA. Scope of practice and autonomy of physician assistants in rural versus urban emergency departments. Acad Emerg Med. 2014 May;21(5):520-5. PubMed PMID: 24842502
Ginde AA, Moss M. Lung-protective ventilation in emergency department patients with severe sepsis. Acad Emerg Med. 2014 Jan;21(1):96-7. PubMed PMID: 24320970
Kedia S, Ginde AA, Grubenhoff JA, Kempe A, Hershey AD, Powers SW. Monthly variation of United States pediatric headache emergency department visits. Cephalalgia. 2014 May;34(6):473-8. PubMed PMID: 24335850
Capp R, Rooks SP, Wiler JL, Zane RD, Ginde AA. National study of health insurance type and reasons for emergency department use. J Gen Intern Med. 2014 Apr;29(4):621-7. PubMed PMID: 24366398
Vinton DT, Capp R, Rooks SP, Abbott JT, Ginde AA. Frequent users of US emergency departments: characteristics and opportunities for intervention. Emerg Med J. 2014 Jan 28. [Epub ahead of print] PubMed PMID: 24473411
Valley MA, Trotter JF, Thomas D, Ginde AA, Lownenstein SR, Honigman B. The relationship between hepatopulmonary syndrome and altitude. Can J Gastroenterol Hepatol. 2014 Mar;28(3):140-2. PubMed PMID: 24619635
Honigman LS, Wiler JL, Rooks S, Ginde AA. National Study of Non-urgent Emergency Department Visits and Associated Resource Utilization. West J Emerg Med. 2013 Nov;14(6):609-16. PubMed PMID: 24381681
Vogel JA, Ginde AA, Lowenstein SR, Betz ME. Emergency department visits by older adults for motor vehicle collisions. West J Emerg Med. 2013 Nov;14(6):576-81. PubMed PMID: 24381674
Capp R, Rooks SP, Wiler JL, Zane RD, Ginde AA. National Study of Health Insurance Type and Reasons for Emergency Department Use. J Gen Intern Med. 2013 Dec 24. [Epub ahead of print] PubMed PMID: 24366398
Kedia S, Ginde AA, Grubenhoff JA, Kempe A, Hershey AD, Powers SW. Monthly variation of United States pediatric headache emergency department visits. Cephalalgia. 2013 Dec 11. [Epub ahead of print] PubMed PMID: 24335850
Herring AA, Johnson B, Ginde AA, Camargo CA, Feng L, Alter HJ, Hsia R. High-intensity emergency department visits increased in California, 2002-09. Health Aff (Millwood). 2013 Oct;32(10):1811-9. PubMed PMID: 24101073
Nacht J, Macht M, Ginde AA. Interhospital transfers from U.S. emergency departments: implications for resource utilization, patient safety, and regionalization. Acad Emerg Med. 2013 Sep;20(9):888-93. PubMed PMID: 24033705
Gunville CF, Mourani PM, Ginde AA. The role of vitamin D in prevention and treatment of infection. Inflamm Allergy Drug Targets. 2013 Aug;12(4):239-45. PubMed PMID: 23782205
Ginde AA, Moss M, Shapiro NI, Schwartz RS. Impact of older age and nursing home residence on clinical outcomes of US emergency department visits for severe sepsis. J Crit Care. 2013 Oct;28(5):606-11. PubMed PMID: 23683561
Herring AA, Ginde AA, Fahimi J, Alter HJ, Maselli JH, Espinola JA, Sullivan AF, Camargo CA Jr. Increasing critical care admissions from U.S. emergency departments, 2001-2009. Crit Care Med. 2013 May;41(5):1197-204. PubMed PMID: 23591207
King RA, Liu KY, Talley BE, Ginde AA. Availability and potential impact of international rotations in emergency medicine residency programs. J Emerg Med. 2013 Feb;44(2):499-504. PubMed PMID: 23040675