Calen Steiner, MD
Assistant Professor, Medicine-Gastroenterology

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Medical School:
  • MD, University of Cincinnati College of Medicine (2015)
Graduate School :
  • MS, University of Cincinnati (2011)
Undergraduate School:
  • BS, University of California–Los Angeles (CA) (2007)
Residency:
  • University of Michigan Program, Internal Medicine (2018)
Fellowships:
  • University of Michigan Program, Gastroenterology (2021)
Department: Medicine-Gastroenterology

Publications

  • Berinstein EM, Sheehan JL, Jacob J, Steiner CA, Stidham RW, Shannon C, Bishu S, Levine J, Cohen-Mekelburg SA, Waljee AK, Higgins PDR, Berinstein JA. Correction to: Efficacy and Safety of Dual Targeted Therapy for Partially or Non-responsive Inflammatory Bowel Disease: A Systematic Review of the Literature. Dig Dis Sci. 2023 Dec;68(12):4540. PubMed PMID: 37891442
  • Steiner CA, Koch SD, Evanoff T, Welch N, Kostelecky R, Callahan R, Murphy EM, Nguyen TT, Hall CHT, Lu S, de Zoeten EF, Weiser-Evans MCM, Cartwright IM, Colgan SP. The TNF(?ARE) Mouse as a Model of Intestinal Fibrosis. Am J Pathol. 2023 Aug;193(8):1013-1028. PubMed PMID: 37169343
  • Berinstein JA, Steiner CA, Rifkin S, Alexander Perry D, Micic D, Shirley D, Higgins PDR, Young VB, Lee A, Rao K. A Predictive Model to Identify Complicated Clostridiodes difficile Infection. Open Forum Infect Dis. 2023 Feb;10(2):ofad049. PubMed PMID: 36820317
  • Berinstein EM, Sheehan JL, Jacob J, Steiner CA, Stidham RW, Shannon C, Bishu S, Levine J, Cohen-Mekelburg SA, Waljee AK, Higgins PDR, Berinstein JA. Efficacy and Safety of Dual Targeted Therapy for Partially or Non-responsive Inflammatory Bowel Disease: A Systematic Review of the Literature. Dig Dis Sci. 2023 Jun;68(6):2604-2623. PubMed PMID: 36807832
  • Steiner CA, Koch SD, Evanoff T, Welch N, Kostelecky R, Callahan R, Murphy EM, Hall CHT, Lu S, Weiser-Evans MC, Cartwright IM, Colgan SP. The TNF (?ARE) mouse as a model of intestinal fibrosis. bioRxiv. 2023 Jan 14. PubMed PMID: 36712048
  • Steiner CA, Cartwright IM, Taylor CT, Colgan SP. Hypoxia-inducible factor as a bridge between healthy barrier function, wound healing, and fibrosis. Am J Physiol Cell Physiol. 2022 Sep 1;323(3):C866-C878. PubMed PMID: 35912990
  • Cartwright IM, Dowdell AS, Hanson C, Kostelecky RE, Welch N, Steiner CA, Colgan SP. Contact-dependent, polarized acidification response during neutrophil-epithelial interactions. J Leukoc Biol. 2022 Dec;112(6):1543-1553. PubMed PMID: 35674095
  • Sheehan JL, Jacob J, Berinstein EM, Greene-Higgs L, Steiner CA, Berry SK, Shannon C, Cohen-Mekelburg SA, Higgins PDR, Berinstein JA. The Relationship Between Opioid Use and Healthcare Utilization in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis. Inflamm Bowel Dis. 2022 Dec 1;28(12):1904-1914. PubMed PMID: 35230420
  • Steiner CA, Rieder F. No Longer Stretching Credibility: Mechanical Force Meets Inflammation in Experimental Intestinal Stenosis. Dig Dis Sci. 2022 May;67(5):1702-1703. PubMed PMID: 34350517
  • Johnson LA, Rodansky ES, Tran A, Collins SG, Eaton KA, Malamet B, Steiner CA, Huang S, Spence JR, Higgins PDR. Effect of ABT-263 on Intestinal Fibrosis in Human Myofibroblasts, Human Intestinal Organoids, and the Mouse Salmonella typhimurium Model. Inflamm Bowel Dis. 2022 Feb 1;28(2):161-175. PubMed PMID: 34302470
  • Steiner CA, Berinstein JA, Louissaint J, Higgins PDR, Spence JR, Shannon C, Lu C, Stidham RW, Fletcher JG, Bruining DH, Feagan BG, Jairath V, Baker ME, Bettenworth D, Rieder F. Biomarkers for the Prediction and Diagnosis of Fibrostenosing Crohn's Disease: A Systematic Review. Clin Gastroenterol Hepatol. 2022 Apr;20(4):817-846.e10. PubMed PMID: 34089850
  • Steiner C. A commentary on: Complete endoscopic healing is associated with a lower relapse risk after anti-TNF withdrawal in inflammatory bowel disease. PracticeUpdate website. Available at: https://www.practiceupdate.com/content/complete-endoscopic-healing-lowers-relapse-risk-after-anti-tnf-therapy-withdrawal-in-ibd/141630/65/9/1. Accessed October 10, 2022
  • Steiner C. A commentary on: Ozanimod as Induction and Maintenance Therapy for Ulcerative Colitis. PracticeUpdate website. Available at: https://www.practiceupdate.com/content/ozanimod-as-therapy-for-ulcerative-colitis/132003/65/9/1. Accessed March 04, 2022
  • Steiner CA, Rodansky ES, Johnson LA, Berinstein JA, Cushing KC, Huang S, Spence JR, Higgins PDR. AXL Is a Potential Target for the Treatment of Intestinal Fibrosis. Inflamm Bowel Dis. 2021 Feb 16;27(3):303-316. PubMed PMID: 32676663
  • Berinstein JA, Cohen-Mekelburg SA, Steiner CA, McLeod M, Noureldin M, Allen JI, Kullgren JT, Waljee AK, Higgins PDR. Variations in Health Care Utilization Patterns Among Inflammatory Bowel Disease Patients at Risk for High Medical Service Utilization Enrolled in High Deductible Health Plans. Inflamm Bowel Dis. 2021 May 17;27(6):771-778. PubMed PMID: 32676638
  • Berinstein JA, Steiner CA, Higgins PDR. Reply. Clin Gastroenterol Hepatol. 2021 Jun;19(6):1303-1304. PubMed PMID: 33248182
  • Berinstein JA, Steiner CA, Roth KJ, Briggs E, Rao K, Higgins PDR. Association of Household Pets, Common Dietary Factors, and Lifestyle Factors with Clostridium difficile Infection. Dig Dis Sci. 2021 Jan;66(1):206-212. PubMed PMID: 32036514
  • Berinstein JA, Sheehan JL, Dias M, Berinstein EM, Steiner CA, Johnson LA, Regal RE, Allen JI, Cushing KC, Stidham RW, Bishu S, Kinnucan JAR, Cohen-Mekelburg SA, Waljee AK, Higgins PDR. Tofacitinib for Biologic-Experienced Hospitalized Patients With Acute Severe Ulcerative Colitis: A Retrospective Case-Control Study. Clin Gastroenterol Hepatol. 2021 May 25:S1542-3565(21)00576-0. doi: 10.1016/j.cgh.2021.05.038. Epub ahead of print. PMID: 34048936.
  • Steiner CA, Berinstein JA, Louissaint J, Higgins PDR, Spence JR, Shannon C, Lu C, Stidham RW, Fletcher JG, Bruining DH, Feagan BG, Jairath V, Baker ME, Bettenworth D, Rieder F; Stenosis Therapy and Anti-Fibrotic Research (STAR) Consortium. Biomarkers for the Prediction and Diagnosis of Fibrostenosing Crohn's Disease: A Systematic Review. Clin Gastroenterol Hepatol. 2021 Jun 2:S1542-3565(21)00593-0. doi: 10.1016/j.cgh.2021.05.054. Epub ahead of print. PMID: 34089850.
  • Steiner CA, Berinstein JA, Louissaint J, Higgins PDR, Spence JR, Shannon C, Lu C, Stidham RW, Fletcher JG, Bruining DH, Feagan BG, Jairath V, Baker ME, Bettenworth D, Rieder F. Biomarkers for the Prediction and Diagnosis of Fibrostenosing Crohn's Disease: A Systematic Review. Clin Gastroenterol Hepatol. 2021 Jun 2. [Epub ahead of print] PubMed PMID: 34089850
  • Berinstein JA, Sheehan JL, Dias M, Berinstein EM, Steiner CA, Johnson LA, Regal RE, Allen JI, Cushing KC, Stidham RW, Bishu S, Kinnucan JAR, Cohen-Mekelburg SA, Waljee AK, Higgins PDR. Tofacitinib for Biologic-Experienced Hospitalized Patients With Acute Severe Ulcerative Colitis: A Retrospective Case-Control Study. Clin Gastroenterol Hepatol. 2021 Oct;19(10):2112-2120.e1. PubMed PMID: 34048936
  • Johnson LA, Rodansky ES, Tran A, Collins SG, Eaton KA, Malamet B, Steiner CA, Huang S, Spence JR, Higgins PDR. Effect of ABT-263 on Intestinal Fibrosis in Human Myofibroblasts, Human Intestinal Organoids, and the Mouse Salmonella typhimurium Model. Inflamm Bowel Dis. 2021 Jul 24. [Epub ahead of print] PubMed PMID: 34302470
  • Steiner CA, Rodansky ES, Johnson LA, Berinstein JA, Cushing KC, Huang S, Spence JR, Higgins PDR. AXL Is a Potential Target for the Treatment of Intestinal Fibrosis. Inflamm Bowel Dis. 2021 Feb 16;27(3):303-316. PubMed PMID: 32676663
  • Berinstein JA, Steiner CA, Higgins PDR. Reply. Clin Gastroenterol Hepatol. 2021 Jun;19(6):1303-1304. PubMed PMID: 33248182
  • Berinstein JA, Cohen-Mekelburg SA, Steiner CA, McLeod M, Noureldin M, Allen JI, Kullgren JT, Waljee AK, Higgins PDR. Variations in Health Care Utilization Patterns Among Inflammatory Bowel Disease Patients at Risk for High Medical Service Utilization Enrolled in High Deductible Health Plans. Inflamm Bowel Dis. 2021 May 17;27(6):771-778. PubMed PMID: 32676638
  • Berinstein JA, Steiner CA, Roth KJ, Briggs E, Rao K, Higgins PDR. Association of Household Pets, Common Dietary Factors, and Lifestyle Factors with Clostridium difficile Infection. Dig Dis Sci. 2021 Jan;66(1):206-212. PubMed PMID: 32036514
  • Chen VL, Hawa F, Berinstein JA, Reddy CA, Kassab I, Platt KD, Hsu CY, Steiner CA, Louissaint J, Gunaratnam NT, Sharma P. Hepatic Steatosis Is Associated with Increased Disease Severity and Liver Injury in Coronavirus Disease-19. Dig Dis Sci. 2021 Sep;66(9):3192-3198. PubMed PMID: 32980956
  • Steiner CA, Rieder, F. No Longer Stretching Credibility: Mechanical Force Meets Inflammation in Experimental Intestinal Stenosis. Digestive Diseases and Sciences. (2021). https://doi.org/10.1007/s10620-021-07170-4
  • Steiner CA, Bishu S. Concise Commentary: Armchair Science Redux-How Advanced In Silico Analysis Revealed Novel Insights into the Pathogenesis of Acute Pancreatitis. Dig Dis Sci. 2020 Jun;65(6):1733-1734. PubMed PMID: 31993895
  • Chen VL, Hawa F, Berinstein JA, Reddy CA, Kassab I, Platt KD, Hsu CY, Steiner CA, Louissaint J, Gunaratnam NT, Sharma P. Hepatic Steatosis Is Associated with Increased Disease Severity and Liver Injury in Coronavirus Disease-19. Dig Dis Sci. 2020 Sep 27:1–7. doi: 10.1007/s10620-020-06618-3. Epub ahead of print. PMID: 32980956; PMCID: PMC7520076.
  • Xu D, Chen VL, Steiner CA, Berinstein JA, Eswaran S, Waljee AK, Higgins PDR, Owyang C. Efficacy of Fecal Microbiota Transplantation in Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis. Am J Gastroenterol. 2019 Jul;114(7):1043-1050. PubMed PMID: 30908299
  • Berinstein JA, Steiner CA, Regal RE, Allen JI, Kinnucan JAR, Stidham RW, Waljee AK, Bishu S, Aldrich LB, Higgins PDR. Efficacy of Induction Therapy With High-Intensity Tofacitinib in 4 Patients With Acute Severe Ulcerative Colitis. Clin Gastroenterol Hepatol. 2019 Apr;17(5):988-990.e1. PubMed PMID: 30458248
  • Jeffrey A Berinstein, MD, MSc, Calen A Steiner, MD, MS, Athos Bousvaros, MD, MPH, Felix P Tiongco, MD, Eugene Greenberg, MD, Robert Hardi, MD, Anthony J Lembo, MD, Keith Friedenberg, MD, Shahriar Sedghi, MD, Alison Fint, BS, David A Florez, MD, Ashutosh Kumar, MS, Razvan Arsenescu, MD, K T Park, MD, MS, Peter Kupchak, PhD, Alanna Grob, BS, MT, James Leavitt, MD, Peter D R Higgins, MD, PhD, MSc, The Clinical Accuracy of the BÜHLMANN fCAL ELISA in the Differentiation of Inflammatory Bowel Disease From Irritable Bowel Syndrome: A Multicenter Prospective Case–Control Study, Crohn's & Colitis 360, Volume 1, Issue 3, October 2019, otz037, https://doi.org/10.1093/crocol/otz037
  • Berinstein JA, Steiner CA, Higgins PDR. The IBD Therapeutic Pipeline is Primed to Produce. Practical Gastro, 2019 April; 43(4):24-26,30-32,38-40,42,44-45,52-54,56-60,52
  • Steiner C.A., Higgins P.D.R. (2018) Anti-Fibrotic Therapies from Other Organs: What the Gut Can Learn from the Liver, Skin, Lung and Heart. In: Rieder F. (eds) Fibrostenotic Inflammatory Bowel Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-90578-5_23
  • Steiner C.A., Whitfield E.P., Adler J., Higgins P.D.R. (2017) Anti-TNF Biologic Therapies Other than Infliximab. In: Mamula P., Grossman A., Baldassano R., Kelsen J., Markowitz J. (eds) Pediatric Inflammatory Bowel Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-49215-5_33
  • Serrone JC, Tackla RD, Gozal YM, Hanseman DJ, Gogela SL, Vuong SM, Kosty JA, Steiner CA, Krueger BM, Grossman AW, Ringer AJ. Aneurysm growth and de novo aneurysms during aneurysm surveillance. J Neurosurg. 2016 Dec;125(6):1374-1382. PubMed PMID: 26967775
  • Apostolova LG, Thompson PM, Rogers SA, Dinov ID, Zoumalan C, Steiner CA, Siu E, Green AE, Small GW, Toga AW, Cummings JL, Phelps ME, Silverman DH. Surface feature-guided mapping of cerebral metabolic changes in cognitively normal and mildly impaired elderly. Mol Imaging Biol. 2010 Apr;12(2):218-24. PubMed PMID: 19636640
  • Apostolova LG, Steiner CA, Akopyan GG, Dutton RA, Hayashi KM, Toga AW, Cummings JL, Thompson PM. Three-dimensional gray matter atrophy mapping in mild cognitive impairment and mild Alzheimer disease. Arch Neurol. 2007 Oct;64(10):1489-95. PubMed PMID: 17923632
  • Apostolova LG, Akopyan GG, Partiali N, Steiner CA, Dutton RA, Hayashi KM, Dinov ID, Toga AW, Cummings JL, Thompson PM. Structural correlates of apathy in Alzheimer's disease. Dement Geriatr Cogn Disord. 2007;24(2):91-7. PubMed PMID: 17570907
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Practice Locations

UCHealth Crohn’s and Colitis Center - Anschutz Medical Campus
1635 Aurora Ct
6th Floor
Aurora, CO 80045
720-848-2777

UCHealth Digestive Health Center - Anschutz Medical Campus
1635 Aurora Ct
5th Floor
Aurora, CO 80045
720-848-2777

Hospital Affiliation
  • University of Colorado Hospital

Specialty Information

Specialties
  • Internal Medicine, Board Certification (2018)
  • Gastroenterology
Conditions & Treatments
  • Digestive System
  • Digestive System - Inflammatory Bowel Disease (IBD): Crohn’s disease, ulcerative colitis, microscopic colitis
Clinical Interests
My many clinical interests include the medical and endoscopic management of patients with Inflammatory Bowel Disease (IBD) including Crohn's Disease and Ulcerative Colitis.

Care Philosophy
I strive to provide the best care for my patients. I believe in a multidisciplinary and comprehensive approach to care for the person as a whole and delivering cutting edge, evidence-based care for our patients.

General Information

Medical Schools:
  • MD, University of Cincinnati College of Medicine (2015)
Graduate Schools:
  • MS, University of Cincinnati (2011)
Undergraduate Schools:
  • BS, University of California–Los Angeles (CA) (2007)
Residency Programs:
  • University of Michigan Program, Internal Medicine (2018)
Fellowships:
  • University of Michigan Program, Gastroenterology (2021)
Department: Medicine-Gastroenterology
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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