Silvania Teixeira, PhD
Assistant Professor, Pediatrics-Nutrition
Professional Titles
- Assistant Professor
Recognition & Awards
-
Use of 3.3'-T2 and metformin co-treatment for late-stage Type 2 Diabetes (T2D), L'Oreal USA For Women in Science
(2020)
The L'Oréal USA For Women in Science (FWIS) fellowship program annually awards five women postdoctoral scientists grants for their contributions to Science, Technology, Engineering, and Math (STEM) fields and their commitment to serving as role models for younger generations.
Publications
- Beck J, da Silva Teixeira S, Harrison K, Phillips G, He Y, Sisley S. Paraventricular Vitamin D Receptors Are Required for Glucose Tolerance in Males but Not Females. Front Endocrinol (Lausanne). 2022;13:869678. PubMed PMID: 35620386
- Kozuka C, Efthymiou V, Sales VM, Zhou L, Osataphan S, Yuchi Y, Chimene-Weiss J, Mulla C, Isganaitis E, Desmond J, Sanechika S, Kusuyama J, Goodyear L, Shi X, Gerszten RE, Aguayo-Mazzucato C, Carapeto P, Teixeira SD, Sandoval D, Alonso-Curbelo D, Wu L, Qi J, Patti ME. Bromodomain Inhibition Reveals FGF15/19 As a Target of Epigenetic Regulation and Metabolic Control. Diabetes. 2022 May 1;71(5):1023-1033. PubMed PMID: 35100352
- Liu H, He Y, Beck J, da Silva Teixeira S, Harrison K, Xu Y, Sisley S. Defining vitamin D receptor expression in the brain using a novel VDR(Cre) mouse. J Comp Neurol. 2021 Jun;529(9):2362-2375. PubMed PMID: 33368246
- da Silva Teixeira S, Harrison K, Uzodike M, Rajapakshe K, Coarfa C, He Y, Xu Y, Sisley S. Vitamin D actions in neurons require the PI3K pathway for both enhancing insulin signaling and rapid depolarizing effects. J Steroid Biochem Mol Biol. 2020 Jun;200:105690. PubMed PMID: 32408067
- Prieto-Almeida F, Panveloski-Costa AC, Crunfli F, da Silva Teixeira S, Nunes MT, Torrão ADS. Thyroid hormone improves insulin signaling and reduces the activation of neurodegenerative pathway in the hippocampus of diabetic adult male rats. Life Sci. 2018 Jan 1;192:253-258. PubMed PMID: 29132997
- da Silva Teixeira S, Filgueira C, Sieglaff DH, Benod C, Villagomez R, Minze LJ, Zhang A, Webb P, Nunes MT. 3,5-diiodothyronine (3,5-T2) reduces blood glucose independently of insulin sensitization in obese mice. Acta Physiol (Oxf). 2017 Jun;220(2):238-250. PubMed PMID: 27770485
- Teixeira SD, Panveloski-Costa AC, Carvalho A, Monteiro Schiavon FP, Ruiz Marque AC, Campello RS, Bazotte RB, Nunes MT. Thyroid hormone treatment decreases hepatic glucose production and renal reabsorption of glucose in alloxan-induced diabetic Wistar rats. Physiol Rep. 2016 Sep;4(18). PubMed PMID: 27655796
- Panveloski-Costa AC, Silva Teixeira S, Ribeiro IM, Serrano-Nascimento C, das Neves RX, Favaro RR, Seelaender M, Antunes VR, Nunes MT. Thyroid hormone reduces inflammatory cytokines improving glycaemia control in alloxan-induced diabetic wistar rats. Acta Physiol (Oxf). 2016 Jun;217(2):130-40. PubMed PMID: 26748816
- Serrano-Nascimento C, Nicola JP, Teixeira Sda S, Poyares LL, Lellis-Santos C, Bordin S, Masini-Repiso AM, Nunes MT. Excess iodide downregulates Na( )/I(-) symporter gene transcription through activation of PI3K/Akt pathway. Mol Cell Endocrinol. 2016 May 5;426:73-90. PubMed PMID: 26872612
- Yonamine CY, Teixeira SS, Campello RS, Gerlinger-Romero F, Rodrigues CF Jr, Guimarães-Ferreira L, Machado UF, Nunes MT. Beta hydroxy beta methylbutyrate supplementation impairs peripheral insulin sensitivity in healthy sedentary Wistar rats. Acta Physiol (Oxf). 2014 Sep;212(1):62-74. PubMed PMID: 24962220
- Serrano-Nascimento C, da Silva Teixeira S, Nicola JP, Nachbar RT, Masini-Repiso AM, Nunes MT. The acute inhibitory effect of iodide excess on sodium/iodide symporter expression and activity involves the PI3K/Akt signaling pathway. Endocrinology. 2014 Mar;155(3):1145-56. PubMed PMID: 24424051
- Goulart-Silva F, Serrano-Nascimento C, Texeira SS, Nunes MT. Triiodothyronine (T3) induces proinsulin gene expression by activating PI3K: possible roles for GSK-3ß and the transcriptional factor PDX-1. Exp Clin Endocrinol Diabetes. 2013 Jan;121(1):14-9. PubMed PMID: 23147208
- Teixeira SS, Tamrakar AK, Goulart-Silva F, Serrano-Nascimento C, Klip A, Nunes MT. Triiodothyronine acutely stimulates glucose transport into L6 muscle cells without increasing surface GLUT4, GLUT1, or GLUT3. Thyroid. 2012 Jul;22(7):747-54. PubMed PMID: 22663547
- Goulart-Silva F, Teixeira Sda S, Luchessi AD, Dos Santos LR, Rebelato E, Carpinelli AR, Nunes MT. Potential contribution of translational factors to triiodo-L-thyronine-induced insulin synthesis by pancreatic beta cells. Thyroid. 2012 Jun;22(6):637-42. PubMed PMID: 22667453
- Brunetto EL, Teixeira Sda S, Giannocco G, Machado UF, Nunes MT. T3 rapidly increases SLC2A4 gene expression and GLUT4 trafficking to the plasma membrane in skeletal muscle of rat and improves glucose homeostasis. Thyroid. 2012 Jan;22(1):70-9. PubMed PMID: 22136156
- Saraiva PP, Teixeira SS, Padovani CR, Nogueira CR. Triiodothyronine (T3) does not induce Rankl expression in rat Ros 17/2.8 cells. Arq Bras Endocrinol Metabol. 2008 Feb;52(1):109-13. PubMed PMID: 18345403
- Saraiva PP, Teixeira SS, Conde SJ, Nogueira CR. The importance of hormone receptor analysis in osteosarcoma cells growth submitted to treatment with estrogen in association with thyroid hormone. Cell Biochem Funct. 2008 Jan-Feb;26(1):107-10. PubMed PMID: 17437320
- Perone D, Teixeira SS, Clara SA, Santos DC, Nogueira CR. [Genetic aspects in congenital hypothyrodism]. Arq Bras Endocrinol Metabol. 2004 Feb;48(1):62-9. PubMed PMID: 15611819
Public Speaking
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Yes